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Bird Flu

Study results from University of Illinois provide new insights into bird flu

Published in Health Risk Factor Week, August 4th, 2009

According to recent research from the United States, "Avian influenza virus H5N1 is a major concern as a potential global pandemic. It is thought that multiple key events must take place before efficient human-to-human transmission of the virus occurs."

"The first step in overcoming host restriction is viral entry which is mediated by HA, responsible for both viral attachment and viral/host membrane fusion. HA binds to glycans-containing receptors with terminal sialic acid (SA). It has been shown that avian influenza viruses preferentially bind to alpha 2,3-linked SAs, while human influenza A viruses exhibit a preference for alpha 2,6-linked SAs. Thus it is believed the...

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