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Graves Disease

Studies from University of Duisburg-Essen provide new data on Graves disease

Published in Health Risk Factor Week, September 8th, 2009

"Genotypes of the T393C SNP of GNAS1, a gene that encodes for the G alpha s subunit of G proteins have been significantly associated with the clinical course in a variety of cancers. Since this SNP may also influence the course of Graves' disease (GD) and, especially, Graves' ophthalmopathy (GO), we determined genotype and allele frequency in a series of 359 patients, which were referred to our clinic within 6 months of the onset of GO," scientists writing in the journal Hormone and Metabolic Research report.

"Among them, 336 patients also suffered from associated hyperthyroidism. Data on relapse and remission rates 12 months after termination of a 1 year...

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