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Renal Disease

Reports summarize renal disease research from Yonsei University, Medical Department

Published in Health Risk Factor Week, February 2nd, 2010

"Angiotensin II receptor blockers (ARBs) reduce proteinuria, however, with large inter-individual variability. The present study investigated whether urinary transforming growth factor-beta 1 (TGF-beta 1) might predict the antiproteinuric efficacy of ARB in non-diabetic chronic renal disease," scientists in Seoul, South Korea report.

"Non-diabetic patients with proteinuria (>1 g/day) received 50 mg of losartan daily followed by 100 mg in two treatment periods, each lasting 12 weeks. Clinical parameters and urinary TGF-beta 1 levels were measured at baseline and during the treatment period. In the whole group of patients, losartan treatment effectively decreased...

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