Alcoholism

Neurosteroids May Be Missing Link

Published in Health and Medicine Week, January 15th, 2000

A natural brain compound called a neurosteroid may be the missing link between alcohol and a major neurotransmitter called gamma-aminobutyric acid (GABA).

Alcohol's effects on GABA receptors in the brain were known to cause the relaxing, sedative, anticonvulsant, and intoxicating effects of alcohol but, until recently, researchers didn't know exactly how. Now they believe, as outlined in the December 1999 issue of Alcoholism: Clinical & Experimental Research Symposium Proceedings, they have found the missing piece of the puzzle.

"Neurosteroids are steroid compounds that are called neurosteroids for two reasons," explained A. Leslie Morrow,...

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Source: Health and Medicine Week (2000-01-15)

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