Susan Hasty, Publisher
Table of Contents . . . September 1st, 2003
Non-Subscriber - Summaries OnlyRelated Areas: Other Issues in Health and Medicine Week | Other Publications
Adolescent Medicine - Relationship-based intervention improves maternal sensitivity in young mothers
Tissue Engineering - Carnegie Mellon develops new process for growing bone
Complementary and Alternative Medicine - Brain scans, blood tests show positive effects of meditation
Exercise - Women benefit from physical activity during and after menopause
Fitness - Physical activity definitions broadened to include daily activities
HIV/AIDS Epidemiology - Prevalence of HIV infection increasing in older Americans
Pain Medicine - Hypnosis doesn't improve pain relief strategies
Acute Leukemia - Targeting TNF pathway along with ATRA may represent route to treat leukemias
Adhesions - Biomaterials company receives U.S. patent on polymer technology
Algal Immune Effectors - Polysaccharide extracts from different algae produce different immune effects
Allergic Rhinitis - Mast cell product-antagonizing is short-term treatment, long-term solutions needed
Allergic Rhinitis - Rhinitis immunotherapy using specific subcutaneous allergen is better than drugs
Allergies - Latex allergy may create cross-reactive fruit allergies; kiwi is highest risk
Allergy Medicine - Protein digestibility related to allergenicity
Alzheimer Disease - As U.S. population ages, AD prevalence expected to increase substantially
Alzheimer Disease - Regulation of glucose by HIF-1 protects neurons from amyloid beta peptide
Amyotrophic Lateral Sclerosis - Catalytic antioxidant, AEOL 10150, selected for development as ALS treatment
Amyotrophic Lateral Sclerosis - Rights acquired to ALS gene therapy from Salk Institute
Anal Fissure Pain - Progress reported on Cellegesic phase III trial
Aneurysm Repair - Seniority of surgeon did not affect aneurysm surgery outcome
Animal Models - Research hampered by shortage of monkeys
Anorexia Nervosa - Genes showing differential expression in anorexia mutant mouse identified
Antiangiogenesis - Novel 1,3,4-trisubstituted pyrazole derivatives stifle tumor growth mechanisms
Antibiotic Research - Resistance may occur in bacteria if innate antibiotic proteins are used
Antibiotic Resistance - Newly discovered inhibitors of bacterial lactamases may prevent resistance
Antibiotic Resistance - World Health Organization: Farmers should cut antibiotic use
Antibiotics - N- and C-terminal modifications of negamycin affect antibacterial activity
Antiemetics - Swiss pharmaceutical group announces European drug submission for palonosetron
Antifungal Research - Gallerimycin, a moth-derived antifungal peptide, isn't active against yeast
Antimetastatic Action - TSLC1 gene in human lung cancer is probably a cell adhesion molecule
Antimicrobial Resistance - Vancomycin-resistant infections are low among liver transplant candidates
Antisense Technology - Egr-1 inhibition reverses the transformation of prostate cancer cells
Antisense Technology - New MAST technology has universal applications for tracking desired mRNA sites
Antiviral Therapy - Novel DSTP derivative inhibits growth of HIV and herpesviruses
Antiviral Therapy - Several factors contribute to treatment failure in chronic hepatitis C
Arousal - Researchers close in on scientific definition of arousal
Artificial Heart - Ventracor reports on first patient
Asthma - Airway epithelium is in constant repair; allergens create cyclic Th2 response
Asthma - Biomedical engineer receives $1.8 million grant to study lung damage
Asthma - Disodium chromoglycate doesn't help kids with asthma
Asthma - Food allergy may be a source to consider for asthma of unknown origin
Asthma - Labeling changes required for drug products that contain salmeterol
Asthma - Patent awarded for therapeutic uses of interleukin-9 receptor protein
Asthma - Revotar reports positive results with small molecule selectin antagonist
Asthma - Study links preschool snoring, asthma, and nighttime cough
Asthma - Study of glucocorticoid-receptor interactions may lead to new anti-asthma agents
Asthma Therapy - Nramp gene determines efficacy of mycobacteria-based asthma treatment
Atherosclerosis - Patient enrollment completed in phase IIb CART-2 study with AGI-1067
Atherosclerosis - Vitamins restore blood vessel performance in kids with high cholesterol
Atopic Dermatitis - FDA approves skin emulsion
Atrial Fibrillation - First patient dosed in phase III atrial arrhythmia studies
Autoimmune Disease - Array analysis of autoimmune disease leads to vaccine development
Autoimmune Disease - Autoreactive B lymphocytes may be removable by recombinant fusion proteins
Autoimmune Disease - Some MG seronegative patients may be MuSK antibody positive
Autoimmune Disease - Systemic lupus erythematosus is more prevalent than was previously thought
Autoimmune Disease - Targeted DNA vaccine may reverse disease
B Cell Function - Efficient Vav3 translocation to B cell membrane rafts requires Grb2 and BLNK
Back Injury - Can effective stress management prevent back injuries in nurses?
Bacteriology - Proteinases secreted by Bacillus intermedius during sporulation studied
Barrett Esophagus - FDA approves Photofrin for the ablation of high-grade dysplasia
Bee Venom - Breast cancer, metastasis, growth reduced with i.v. bee venom therapy in murine model
Beta-Thalassemia - Drug may eliminate transfusions in patients with blood disorder
Biliary Cirrhosis - Symptoms, cirrhosis disease progression are known; cause and cure remain elusive
Biliary Stent - Percutaneous transhepatic retrieval of a displaced biliary stent is feasible
Bioengineering - A novel skin model invites new ways to explore angiogenesis in vitro
Bioengineering - Hybrid fermentation devices increase the output of recombinant molecules
Biomarkers - New screening for CAR reveals transfection efficiency in cancer cells
Bipolar Disorder - Dopamine receptor genotype doesn't affect TSD efficacy for bipolar patients
Blood Safety - All donations now screened for West Nile in U.S.
Blood Screening - FDA license granted for new HIV test kit
Bone Marrow Imaging - Diffusion-weighted imaging can detect bone marrow alterations
Bone Marrow Transplant - Antithymocyte globulin lowers GVHD, worsens T-cell deficiency
Bone Regeneration - Collagen-hydroxyapatite/tricalcium phosphate microspheres deliver rhTGF-beta 1
Bone Tumors - Nuclear medicine bone scan can give a potentially misleading appearance
Bone Tumors - Rotationplasty may be an effective partial limb salvage procedure
Bone Tumors - Zoledronic acid will improve patients' quality of life
Borna Disease Virus - Seropositive schizophrenic patients respond to cerebrospinal fluid filtration
Brachytherapy - Company plans to increase sales of I-Plant prostate cancer seed
Brain Cancer - Welsh study set to accelerate search for new treatment
Brain Tumor - Research: GliaSite RTS is a safe and effective treatment for brain tumors
Breast Cancer - Breast cancer screening should be encouraged by general practitioners
Breast Cancer - Duke University's hyperthermia treatment acquired
Breast Cancer - First component of rolling NDA submitted for RSR13
Breast Cancer - Program for low-income women suggests vital importance of access to screening
Breast Cancer - Syngeneic stem cell grafts offer little improvement over autografts for breast cancer patients
Breast Cancer - Systemic redundancies may mask the effects of PAI-1 on cancer inactivation
Breast Cancer - Trial tests treatment for postmenopausal cancer patients who relapse
Breast Implant - De-epithelialized TRAM flaps are an alternative to autologous tissue use
Breastfeeding - Baby-friendly hospitals have positive impact on breastfeeding
Business and Finance - Tennessee insurers compete for customers
Cancer Biomarkers - Cytokine imbalances mark the pathogenesis of chronic lymphocytic leukemia
Cancer Cells - Antibody scFv fragments may be a nuclear delivery system in cancer cells
Cancer Immunotherapy - Diabody-based gene therapy represents a new strategy for cancer therapy
Cancer Metastasis - Prostate cancer invasion is influenced indirectly by TGF beta1 signals
Cancer Therapy - Carboxymethyl benzylamide dextran limits carcinomas in nude mice
Cancer Therapy - G-CSF raises GVHD but not mortality risk in matched sibling stem cell graft recipients
Cancer Therapy - ImClone, Bristol-Myers file application to approve Erbitux
Cancer Therapy - Isolated limb perfusion is feasible for treating cancer and other diseases
Cancer Therapy - Mitochondrial genes linked to tumor cell radiation resistance
Cancer Therapy - PEDF gene transfer suppresses angiogenesis and tumor growth
Cancer Therapy - The gef gene blocks the growth of breast cancer cells
Cancer Therapy - Vascular integrins are targets for cancer containment
Cancer Vaccine - Antibody fragments fused to IL-12 and to TNF-alpha exert anti-tumor effect
Cancer Vaccine - Current developments in cancer vaccines and cellular immunotherapy reviewed
Cancer Vaccine - IL-6 fused to antibody increases immune response against ovarian cancer
Cancer Vaccine - MUC1-derived glycopeptides are strong antigens for breast cancer vaccines
Cancer Vaccine - Peptide vaccine with adjuvant and CTLA-4 blockade elicits antitumor response
Cardiac Hypertrophy - Natural hormone could reverse heart damage
Cardiac Surgery - Intraoperative infusion of magnesium has beneficial effects on surgical outcome
Cardiology - Ex vivo gene transfer improves cardiac function in a swine ischemia model
Cardiology - Exogenous SERCA gene expression depends on CAR levels in cardiac myocytes
Cardiology - John Muir/Mt. Diablo selects TCS Symphony for cath image management/archiving
Cardiology - Premenopausal women have good outcomes after heart attacks with PTCA
Cardiovascular Disease - GATA4 mutation linked to congenital heart defects
Cataracts and Glaucoma - Cataract removal, nonpenetrating glaucoma surgery can be combined
Cell Biology - Endothelial cells overcome hypoxia-induced apoptosis because of CD105
Cell Biology - Scientists create new strain of yeast with 21-amino acid genetic code
Cervical Cancer - Genetically engineered plants produce vaccine components
Cervical Cancer - Papillomavirus E7 protein blocks pCAF's acetyltransferase, a p53 coactivator
Chemotherapy - Circulating VEGF levels change in response to therapy for metastatic cancer
Childhood Immunization - ACPM recommends research priorities for child and adolescent immunizations
Childhood Obesity - Peak heart rate low in obese girls
Chronic Hepatitis B - Thymosin-alpha 1 and interferon combination therapy controls HBV infections
Chronic Hepatitis C - Antigenic escape shifts the antibody balance in hepatitis C-infected patients
Chronic Myeloid Leukemia - Chronic-phase CML patients respond to imatinib, but questions remain
Citrobacter Braakii - LPS polysaccharide from strain PCM 1531 isn't same as others in group O6
Claims Management - Arkansas Blue Cross Blue Shield chooses Webify ClaimsNet
Clear Cell Carcinoma - Three immunohistochemical stains help distinguish clear cell cancer as ovarian or renal
Coagulation - Gln 192 from blood coagulation factor Xa plays key role in function
Cochlear Implant - CT can visualize temporal bone anatomic changes
Cognition - Amyloid-beta peptide impairs short-term but not long-term memory in rats
Collaborations - $50,000 development grant will support Oregon's bioscience industry
Collaborations - Alliance to deliver electronic clinical trial solution
Collaborations - Care management firm announces agreement with Carolinas HealthCare System
Collaborations - Chiropractic company enters agreements for Florida market
Collaborations - Liposome technology company initiates cooperative alliance
Collaborations - Partners HealthCare enters clinical research alliance
Collaborations - Research alliance centers on monoclonal antibody for inflammatory disease
Collaborations - ThinPrep imaging system agreement signed
Collection Management - Einstein Health Network to use HealthPay24 software to increase collections
Colon Cancer - Binding sites for Lewis antigens are expressed by human colon cancer cells
Colon Cancer - Immunochemical fecal occult blood testing can prevent advanced colorectal cancer
Colon Cancer - Moderate doses of vitamin B-6 suppress tumor growth in animal studies
Colorectal Neoplasms - Different genetic pathways may exist in the development of colorectal adenomas
Complementary and Alternative Medicine - Cordyceps pruinosa extract inhibits NF-kappaB gene expression
Complementary and Alternative Medicine - Study calls for major reforms in marketing of ephedra
Congestive Heart Failure - RABBIT trial started to evaluate b-type natriuretic peptide
Contact Lens - Contact lenses help poor visual acuity after unsuccessful refractive surgery
Contraception - Arabic language website launched on emergency contraception
Coronary Artery Bypass - Poverty increases risk of complications and death after CABG
Coronary Artery Disease - Study looks at role of intra-abdominal fat in heart disease in women
Coronary Grafting - Internal thoracic artery can be developed by an inferior epigastric AV fistula
Corporate Update - Chemistry-driven drug discovery company realigns business mission
Correctional Health - Tennessee company to provide healthcare to Pennsylvania prisoners
Crohn Disease - Anti-TNF-antibody therapy shows same results in IL-10 knockout mouse as humans
Cryogenics - Contract signed for exclusive provider for MRI magnet base
Cystinuria - Kidney stone patients can now be reliably tested, treated
Cytokine Control - Protein inhibitor of activated STAT3 and androgen receptor compete for STAT3
Cytomegalovirus - Host cell binding prevented for cytomegalovirus coated with AD-2 antibody
DNA Damage Response - Human Spy1 promotes survival of mammalian cells following DNA damage
DNA Research - Improved single nucleotide polymorphism-based genotype assays developed
DNA Research - Novel HIV-based cDNA cloning system may aid genetic research
DNA Testing - Amelogenin, 17 DNA loci effective as paternity markers in incest case
Dendritic Cell Function - Immature dendritic cells are largely unaffected by apoptotic T cells
Dermatology - Alpha-3-beta-1-integrin regulates hair follicle morphogenesis
Dermatology - EGF receptor may play critical role in suppressing keratinocyte inflammation
Developmental Biology - Clue found as to why small babies have increased risk of heart disease as adults
Diabetes Complications - Vascular endothelial growth factor is fundamental to diabetic retinopathy
Diabetes Epidemiology - Diabetes underdiagnosed in dialysis patients on renal transplant waiting list
Diabetes Epidemiology - Increased prevalence of diabetes - not all bad news
Diabetes Therapy - Allosteric activators of glucokinase show promise for diabetes therapy
Diabetic Nephropathy - Metabolic status affects markers for glomerular filtration rate
Diabetic Nephropathy - Prevention of the development and progression of renal disease reviewed
Diabetic Nephropathy - Study of genetic determinants of diabetic nephropathy launched
Diagnostic Markers - Trio of AFP, PIVKAII, GGTII increases accuracy of liver cancer diagnosis
Diagnostics - Effect of trabecular material on backscatter from cancellous bone reported
Diagnostics - Pediatric Lyme arthritis can be diagnosed using a recombinant IR6 assay
Diagnostics - Primary ocular lymphoma is often diagnosed late, following brain metastasis
Dialysis - Blue Cross unit decides to fully cover drug that prolongs patient survival
Diarrhea - Intestinal polypeptide antagonists considered as antidiarrhea agents
Diet and Nutrition - Some dietary fat reducing behaviors difficult to change in Arab women
Diet and Nutrition - The tendency to overeat predicts food consumption
Disease Management - Balanced outlook helps patients manage depression
Downsizing - Reduction in work force announced at lab-on-a-chip company
Drug Abuse Screening - Agreement signed for use of chemical assay
Drug Assistance Program - Pharmaceutical firm to help state AIDS programs
Drug Benefits - Congressional proposals offer little help to low-income Medicare recipients
Drug Delivery - Company's system helps reduce medication errors
Drug Design - Drugs must target particular compartment where protein they act upon is located
Drug Development - PEDF could potentially treat a variety of angiogenesis-related disorders
Drug Discovery - Inpharmatica secures ADME service agreement with European pharmaceutical company
Drug Importation - Montana moves to halt Canada drugs by mail
Drug Importation - Ohio county's prescription drug program halted
Drug Resistance - Epidemiology of sporadic bloody diarrhea in rural Western Kenya reported
Duodenal Carcinoma - Primary duodenal carcinoma can show divergent growth patterns
Early Learning - Babies determine shapes, objects at early age
Eating Disorders - Anorexia afflicting children as young as 8
Electronic Claims Processing - Claimsnet signs new contract with third party administrator
Electronic Medical Records - Michigan system selects company for connecting patient health data
Emergency Medicine - Dedicated trauma program improves patient outcomes
Emergency Medicine - Disaster relief fund in jeopardy
Emergency Medicine - Neighborhood factors are an independent risk for childhood injury
Employee Benefits - HealthMarket offers consumer driven health plans in Nevada
End-of-Life Care - Michigan group to review hospital "futile care" policies
Endocrine - Intermittent estrogen stimulates cell differentiation and bone formation
Endocrinology - Blue fox handling during pregnancy generates fetal gonadal stress
Endocrinology - First of three phase III exenatide studies achieves positive results
Endocrinology - Hormone replacement has no effect on the bladders of ovariectomized rats
Endometrial Cell Marker - Cold-inducible RNA-binding protein is downregulated in endometrial carcinoma
Environmental Health - Aerosolized mycobacteria may underlie respiratory disease outbreaks
Environmental Health - New method available for detecting toxic mold
Environmental Health - PAH exposure linked to DNA damage in human blood cells
Epidemiology - Black women still hardest hit by fatal breast cancer
Epidemiology - Risk of human ehrlichiosis in Germany present despite no clinical cases
Epidemiology - Sickness records can predict employee deaths
Epidemiology - Work done by Emerging Infections Programs outlined
Epilepsy - Foundation welcomes FDA approval of new monotherapy treatment for children
Epilepsy - Ketogenic diet raises cholesterol, lipid levels in children
Epstein Barr Virus - Inflammatory pseudotumor due to clonal EBV-infected cells can occur in spleen
Escherichia Coli - The StcE gene was probably acquired by E. coli O157:H7 via plasmid
Evolution - An MHC-like region of 19 genes is conserved between humans and fruit flies
Evolutionary Biology - Key genes prompt species to converge
Evolutionary Genomics - Pioneering study compares 13 vertebrate genomes
Expansion - Desert Medical Group to take larger role in FDA-based clinical research
Fat Substitute - FDA eliminates current label requirement on snack foods made with Olean
Fertility Medicine - Boston firm close to commercializing a way to freeze human eggs
Fetal Medicine - Midaortic syndrome and cardiomyopathy can give nonimmune fetal hydrops
Fetal Monitoring - Scientists develop greater accuracy in recording baby's heart rates in the womb
Fibroblasts - Autologous cellular therapy company receives license to manufacture in Australia
Finance - ADHD drug maker reports earnings of $0.31 per share
Finance - APF112 phase II submitted for FDA review; royalty income increases 11%
Finance - Actimmune sales increase; company meets guidance
Finance - Allergan collaboration leads to increased revenues for pharmaceutical company
Finance - American Physicians Capital reports income of $0.12 per share
Finance - Biosurgical device company reports net loss of $22.3M
Finance - Biotech company reports $0.36 per share loss
Finance - Biotherapeutics company reports loss of $0.24 per share
Finance - Board authorizes $1B share-repurchase program at medical products firm
Finance - Body monitoring device company raises $4M
Finance - CRO announces second quarter results, reports steadily improving results
Finance - Cell imaging systems provider secures equipment financing line
Finance - Coagulation monitoring systems company closes latest funding round
Finance - Company provides second quarter update, reports on CCR2 receptor antagonist program
Finance - Company receives extension of waivers from EPIL noteholders
Finance - Company updates Cialis progress, reports results for second quarter of 2003
Finance - Company's second quarter marked by record revenues, improved operating results
Finance - Corvas acquisition helps strengthen company's second quarter
Finance - Cross Country Healthcare reports 5% increase in revenue
Finance - Development of Affinitak contributes to company's decreased revenues
Finance - Device company reports 129% increase in net income
Finance - Dialysis company reports net loss of $0.19 per share
Finance - Dialysis company reports second quarter and 6-month results for 2003
Finance - Drug delivery company reports $0.47 per share loss
Finance - Drug discovery company meets second quarter expectation, initiates trials
Finance - Drug discovery firm meets analysts' estimate for revenues, earnings
Finance - Electrophysiology company achieves several milestones in second quarter
Finance - Epilepsy device maker reports 16% increase in sales
Finance - Equity firm to buy stake in nurse staffing company
Finance - Expenses to commercialize PowerLink AAA technology affect 2Q results
Finance - Genomics technology company provides update on its second quarter
Finance - Gentiva reports second quarter net revenue growth of 6.6% and diluted EPS of $0.19
Finance - German biotech reports 11% revenue increase in first half of 2003
Finance - Gliadel Wafer sales increase; company reports net loss in second quarter
Finance - Grants to fund rapid, portable detection systems for HIV, blood lead
Finance - Health Care Property Investors to redeem 7.875% series A preferred stock
Finance - Health Grades reports strong ratings and advisory revenue for second quarter
Finance - Health Net's second quarter EPS climbs 24% to $.63 per diluted share
Finance - Health system cites improved financials as basis for rating upgrade
Finance - HealthSouth sells Florida hospital to generate cash
Finance - Healthcare consulting, management services firm announces 2Q 2003 financial results
Finance - Healthcare supplier reports second quarter diluted EPS up 18% to $0.74
Finance - Hearing-care company has second consecutive quarter of profitable operations
Finance - Heart valve company raises $12.3M in private placement of common stock
Finance - Hormone therapy company raises $10.3M in private placement
Finance - Humana completes offering of $300 million of senior notes
Finance - Imaging company pleased with third quarter progress
Finance - Immunology company reports financial results, discusses Aventis collaboration
Finance - Information technology company pays dividend, launches product
Finance - Information technology company reports fourth quarter of profitability
Finance - Lab services company has a record-setting second quarter
Finance - Lab testing service reports increased patient volumes, revenues in second quarter
Finance - MDE acquisition highlights medical device company's fourth quarter
Finance - Massachusetts HMOs' profits up or about even in 2Q 2003
Finance - NeighborCare helps drive third quarter growth for Genesis Health
Finance - New products contribute to second quarter increases for medical products company
Finance - Oncology drug maker reports 66% increase in revenue
Finance - Pharmaceutical company reports net loss of $0.01 per share
Finance - Pharmaceutical distributor reports earnings of $0.29 per share
Finance - Pharmaceutical firm reports earnings of $2.43 per share
Finance - Pharmaceutical firm reports loss of $0.14 per share
Finance - Phoenix firm completes new $275 million credit facility
Finance - Pneumo Sleeve maker reports second quarter loss of $536,000
Finance - Pricing of note financing announced by occupational health firm
Finance - Pulsatile drug company files with SEC for IPO
Finance - Ribapharm parent reports second quarter 2003 net income of $14.9 million
Finance - Robotics company has profitable second quarter, thanks to record sales
Finance - Rosacea drug maker increases guidance for 2003
Finance - Status of stock offering reported by laser company
Finance - Strong Euro affects urological device maker's second quarter results
Finance - Ther-Rx branded pharma business contributes to increased first quarter revenues
Finance - Venture capital group invests in chloroplast DNA company
Finance - Women's health drug maker reports loss of $0.12 per share
Financing - Series B financing raises $26.4M to fund infectious disease program
Fish Immunomodulator - Shark cartilage has proteoglycans that stimulate macrophage and B, not T cells
Fitness - Counseling helps older adults add exercise to their lives
Fitness - Exercise may prolong men's sex lives
Fitness - People over 40 need frequent exercise to prevent or treat type 2 diabetes
Food Allergy - Pediatric hypersensitivity requires full elimination of the suspected food
Food Allergy - Recent recommendations for food allergen avoidance in children are reconciled
Food Allergy - Treatment for peanut-induced anaphylaxis may soon involve anti-IgE
Food-borne Disease - Vibrio vulnificus strains vary seasonally in the Galveston Bay estuary
Food-borne Disease - All Vibrio vulnificus isolates from market oysters are virulent
Food-borne Disease - Antimicrobial cocktail may reduce bacteria in fresh-cut produce
Food-borne Disease - Bacteriophage: Poultry's welcome virus
Foot Ulcers - OrCel data results published
Fungal Therapy - Caspofungin is first approved agent in new class of antifungals
Gastric Wall Tumors - One trocar method can be used for endo-organ resection of gastric wall tumors
Gastroenterology - Hepatitis C virus patients often form elevated serum lipase levels
Gastroenterology - Organelles of Giardia lamblia trophozoite contain cathepsin C activity
Gastroparesis - Data show Enterra therapy reduces persistent nausea, vomiting
Gene Delivery - The new nonviral GE7 vector system takes advantage of overexpressed receptors
Gene Probes - Spotted long oligonucleotide arrays allow for larger scale gene analysis
Gene Regulation - Specific factors direct iNOS-targeted antisense knockdown in endothelial cells
Gene Therapy Vectors - pTF-FC2 plasmid efficiently transfers genes to plants
Gene Transfer - Adenoviral fiber knob modifications overcome refractory transgene expression
Generic Antibiotic - Cefuroxime axetil tablets - generic equivalent of Ceftin - launched
Genetic Disorders - CAIS may be caused by androgen receptor gene disruption
Genetic Disorders - Folic acid food fortification may not reduce Down syndrome risk
Genetic Disorders - Visual-spatial deficits suitable for neurofibromatosis type-1 diagnosis
Genomics - Tumor and drug-resistant genomes can be shaped by instability and selection
Genomics Agreement - Human Genome Sciences announces license agreement
Genomics and Genetics - Evolutionary history of Australian and New Guinean aborigines described
Genomics and Genetics - Human autosomal nonsyndromic male infertility gene, CATSPER2, identified
Genomics and Genetics - Novel retroviral plasmid library may improve genome research
Genotyping - Hopkins is first U.S. institution to obtain powerful technology
Geriatric Influenza Risk - Influenza A recurrence in myocarditis may cause cardiogenic shock
Geriatrics - Proteins that signal amyloid changes in Alzheimer disease are found in PEX
Glioma - SLIT2 may be glioma tumor suppressor gene
Glucose Control - Open label extension study of Metformin GR reinforces positive phase III results
Guillain Barre Syndrome - Acute flaccid paralysis may be caused by West Nile virus infection
Gynecology - Estradiol implants don't improve the urge syndrome in postmenopausal women
Gynecology - Estrogen receptor expression is differential in gynecological tissues
Gynecology - Oxytocin and estrogen receptor mRNAs change during the rodent estrous cycle
Gynecology - Patient position affects the analysis of pelvic organ prolapse
Gynecology - Spinal neurons involved in the urethrogenital reflex have been identified
Gynecology - Women with urinary tract dysfunction may have bouts of constipation
HIV/AIDS - Kappa-opioid, prostanoid EP3 receptors mediate HIV gp120-induced allodynia
HIV/AIDS Animal Models - Novel SHIV chimera may improve simian HIV models
HIV/AIDS Coinfection - SPECT imaging may replace liver biopsies in HIV/HCV coinfected patients
HIV/AIDS Diagnosis - Finger-stick HIV test is accurate and acceptable to women in Thailand
HIV/AIDS Diagnosis - Novel less-sensitive EIA may improve HIV infection tracking
HIV/AIDS Drug Resistance - Resistance mutation patterns different in subtype B and E HIV strains
HIV/AIDS Gene Therapy - Small interfering RNAs protect stem cells from HIV infection
HIV/AIDS Immunotherapy - Anti-gp41 antibody and interleukin-16 have synergistic anti-HIV effects
HIV/AIDS Neurotoxicity - Neuronal heat shock defenses not activated by HIV gp120
HIV/AIDS Opportunistic Infection - EGFR is a human cytomegalovirus receptor
HIV/AIDS Opportunistic Infection - Neutralizing antibodies don't prevent gB2 CMV reactivation in HIV patients
HIV/AIDS Opportunistic Infection - Substance P expression linked to diarrhea severity during cryptosporidiosis
HIV/AIDS Pathogenesis - Downregulation of cell surface CD4 needed for efficient HIV replication
HIV/AIDS Pathogenesis - HIV nef gene linked to vertical transmission
HIV/AIDS Pathogenesis - No direct interaction between Sp1 and HIV Tat proteins
HIV/AIDS Risk Factor - Sexual behavior labels usefulness limited in sexually active gay men
HIV/AIDS Risk Factor - TNF-alpha-inducible mutation in interferon gamma gene linked to rapid HIV progression
HIV/AIDS Therapy - HIV p24 levels linked to CD4 count change in successfully treated patients
HIV/AIDS Therapy - Novel HEPT analogs show improved antiretroviral activity
HIV/AIDS Therapy - Novel stavudine derivatives synthesized
HIV/AIDS Therapy - Proflavine disrupts HIV Rev protein activity
HIV/AIDS Tuberculosis - Active case-finding needed to identify HIV patients with TB in Africa
HIV/AIDS Vaccine - BlockAide trial to begin in fourth quarter; scientific advisory board formed
HIV/AIDS Vaccine - Tat-expressing Sendai viral vector-booster does not increase protection
Head and Neck Cancer - Endostatin also effective for head and neck cancer
Headache Management - Migraine management program appears to be effective while cutting costs
Health Coverage Tax Credit - Displaced workers in Virginia to get insurance help
Healthcare Access - Aetna signs contract with Cleveland Clinic Florida
Healthcare Access - Insured people with usual source of care are more likely to seek healthcare
Healthcare Access - OHSU sees spike in uninsured emergency visits
Healthcare Access - South Africa's health ministry to work up plan for distributing AIDS drugs
Healthcare Insurance - Task force in Wyoming tackles insurance problem
Heart Disease Risk - Most CHD patients have at least one major risk factor
Heart Failure - CardioPass synthetic coronary artery bypass graft implanted in baby
Helicobacter Pylori - VirB8 homologue essential to secretion system of H. pylori analyzed
Helicobacter Pylori - Mechanisms of action of Helicobacter pylori virulence factors studied
Helper T Cells - Inducible costimulator ICOS is involved in T cell activation, IL-4 production
Hematology - Factor VII gene intronic mutation in a lethal factor VII deficiency studied
Hematology - Novel suicide fusion genes stem T cell reactions after transplantation
Hemodialysis - PMA approval granted for ProCol vascular bioprosthesis
Hepatic Lesions - Researchers propose guidelines for liver imaging with multidetector CT
Hepatitis C Virus - TNF-alpha -308 genotype does not affect HCV infection risk or treatment efficacy
Hepatitis Vaccine - Hepatitis vaccines: Recent advances
Hepatocyte Antigen - Hepatocyte antigen may be a marker of intestinal metaplasia
Hepatology - PHKA2 gene analysis useful for X-linked liver glycogenosis diagnosis
Hernia Repair - Laparoscopic repair of paraesophageal hernia with mesh has good results
Herpes Simplex Virus - The HSV ICP8 DNA-binding protein becomes altered upon viral replication setup
Herpesvirus - Herpes simplex virus VP16-induced complex investigated
Herpesvirus - Herpesvirus 8 infection linked to hepatitis B and HIV infections in Ugandans
Hip Arthroplasty - Spiral CT technique can measure bone defects adjacent to acetabular components
Hippocampal - Poly(ADP-ribose) polymerase reduction occurs during stress-related cell death
Hirschsprung Disease - Stem cell defect underlies common genetic disorder
Histamine Receptor Function - Histamine receptors can bind many molecules, resulting in diverse actions
Hospital Acquisition - Dynacq agrees to acquire hospital in Dallas, Texas, area
Hospital Approval - HMA gets recommendation for approval for proposed Florida hospital
Human Tumors - Cyclin E is overexpressed and amplified in many different human tumor types
Huntington Disease - Degree of movement loss reflects brain damage
Hypercholesterolemia - FDA approves new therapy
Hypertension Risk Factor - Activation of central baroreceptor pathway sustained in hypertension
Imaging - Cardius-1, upgradable single-head gamma camera, released
Imaging - Eline Entertainment Group announces formation of imaging sub
Imaging - Researchers distinguish between kinds of dementia using brain imaging
Imaging Purchase - InSight completes purchase of mobile imaging assets in eastern U.S.
Imaging Trends - PET census shows fast growth in PET procedures
Immune Evasion - Peptostreptococcus magnus protein L has immunoglobulin binding domains
Immunology - "Macrophageless" mice have near-normal wound healing
Immunology - Hoxa5 gene loss linked to transient setback in murine thyroid development
Immunology - Chromatin antibodies associate with autoimmune hepatitis pathology
Immunology - Inactivated parapoxvirus ovis protects against hepatitis and herpes viruses
Immunology - Patent granted for ISA247, a calcineurin inhibitor
Immunology - Shark cartilage protein stimulates antitumor immunity in murine models
Immunosuppression - Bone marrow transplant has characteristic risks for pulmonary complications
Immunosuppression Risk - Embryonal rhabdomyosarcoma can occur following liver transplant
Infection Control - Company expands Ramoplanin program with launch of infection control study
Infection Control - E Med Future begins NeedleZap distribution in Uganda
Infection Susceptibility - Mannose-binding lectin quantity, thus infection resistance, may be genetic
Infectious Disease - Aeromonas pathogens carry cagA gene from H. pylori
Infectious Disease - Clostridium species not significant cause of pediatric diarrhea in Brazil
Infectious Disease - Dengue virus serotype 3 viral evolution elucidated
Infectious Disease - Gilead inks nonexclusive HCV licensing agreement, initiate research programs
Infectious Disease - Integron-bearing but drug-susceptible E. coli strains found in Rio Grande
Infectious Disease - New patents granted on oral-dosed, broad-spectrum immune activators
Infectious Disease - The structure of a key enzyme solved
Infectious Disease Diagnostics - Dried blood suitable for immunological RNA testing
Infectious Disease Diagnostics - Novel molecular assay improves E. coli detection in beef products
Infertility - Different techniques can manage ovarian hyperstimulation syndrome
Infertility - Sperm mobility and oocyte number predict multinucleate formation in human IVF
Inflammatory Immunoglobulin - Triggering receptor on myeloid cells can cause sepsis, acute inflammation
Inflammatory Responses - Sex differences in asthma and atopy may relate to hormones
Influenza - Biostatisticians demonstrate method to bolster accuracy of vaccine studies
Influenza - GHRH receptor gene involved in NREMS response to influenza infection in mice
Information Technology - Cancer research organization selects Blue Coat for secure proxy appliance
Information Technology - Children's Hospital of Pittsburgh converts to SET oximetry
Information Technology - Courion delivers identity management support for healthcare applications
Information Technology - Drug information available in handheld database
Information Technology - Foundation Surgery Affiliates to deploy SunriseXA financial solutions
Information Technology - LanVision announces new product installations at medical center
Information Technology - Lee Memorial Health System chooses Sprint for gigabit ethernet system
Inherited Disease - The cathepsin C gene now has 2 mutations linked to Papillon-Lefevre syndrome
Insect Sting Allergy - Insect sting anaphylaxis appears related to mastocytosis, urticaria pigmentosa
Interlukin Expression - IFN-alpha induces binding of IRF-1 and Stat3 to the IL-10 promoter
Interstitial Cystitis - Study finds limited benefit from two oral drugs
Intracranial Aneurysms - FDA approves expanded use of MicroCoil System family of embolic coils
Kidney Disease - Anemia prevalence is extremely high in renal transplant recipients
Kidney Disease - Autosomal recessive Alport syndrome can be a cause of different kidney problems
Kidney Transplant - The use of IVIG in renal transplant may help suppress panel reactive antibodies
Laparoscopic Instruments - Baylor Medical Center commits to AEM surgical instruments
Laryngeal Cancer - Components of fibrinolytic pathways occur in situ in laryngeal cancer
Laser Imaging - Kodak inks global sales agreement for imaging products
Left Ventricular Hypertrophy - New treatment for enlarged heart effective
Legal Issues - Florida investigates Tenet for hospital ties
Legal Issues - Pharmacy groups sue prescription managers
Leishmaniasis - Leishmania major chromosome 3 contains two gene clusters
Leptin Studies - Ins and outs of leptin receptor activation reviewed
Leukemia - Childhood survivors not receiving radiation have same life expectancy as general population
Leukemia - Targeted approaches may lead to better treatment of chronic lymphocytic leukemia
Leukemia - Tumors with a high proliferation index have a poor prognosis
Leukemia - User-defined assays may have applicability in management of leukemia
Leukemia Therapy - AML karyotype strongly influences benefits of pre-HSCT consolidation chemotherapy
Lipoprotein Testing - Doctors Laboratory to offer VAP expanded cholesterol test
Liver Cancer - Organ allocation criteria for hepatocellular carcinoma need review
Liver Failure - Hybrid artificial liver support systems can stem hepatic decline
Liver Lesions - Method for quantifying volumetric lesion change in liver CT scans discussed
Liver Transplantation - Left liver grafts are successful for patients with MELD score less than 15
Liver Transplantation - Monitoring blood samples may be a better way to optimize cyclosporine A dosage
Liver Transplantation - Sonography has poor sensitivity in detecting hepatocellular carcinoma
Liver Tumors - Coded harmonic imaging, Levovist can differentiate hepatocellular carcinoma
Longevity - Brain cell research spawns hope for longer life
Lung Cancer - ALG-2 may be a player in survival pathways in lung cancer
Lung Cancer - New test improves chance of survival
Lung Cancer - Surgical resection of liver metastases may be justified in certain cases
Lung Cancer - Surgical techniques, perioperative care permit more resections in lung cancer
Lung Cancer - Tumor-associated antigen L6 is involved in cancer invasion and metastasis
Lymphoma - Brief chemotherapy plus rituximab is an option for elderly patients with NHL
Lymphoma - Mesenteric malignant lymphoma detected by routine color Doppler ultrasonography
Lymphoma - The anti-CD20 monoclonal antibody rituximab is generally well tolerated
Lymphoma Therapy - R-HDS regimen with stem cell autografting effective against mantle cell lymphoma
Macular Degeneration - Cholesterol lowering drugs may prevent degenerative eye disease
Macular Degeneration - Clinical trial: Squalamine improves vision in wet AMD
Malaria - Exoerythrocytic stages of Plasmodium inui shortti shown in new world monkeys
Malaria - Novel activated C kinase receptor helps regulate plasmodial life cycle
Malaria Diagnosis - Neutrophil lipocalin levels linked to malaria severity
Malaria Pathogenesis - P. falciparum hastens red blood cell senescence
Malaria Therapy - Amodiaquine with SP superior to chloroquine for first-line malaria treatment
Malaria Therapy - Antimalarial action explained by new report
Mandibuloacral Dysplasia - Researchers identify second gene responsible for rare syndrome
Market Analysis - Burn injury management product sales will double
Market Analysis - Coronary heart disease market to reach $23B in 2012
Mathematical Modeling - There are three different models for schistosomiasis transmission
Medicaid - Nebraska must resume payments
Medicaid - New national and state-by-state fact sheets released
Medicaid - Report finds spending rules hurt California, Florida, New York
Medical Equipment - FDA approves stair-climbing wheelchair
Medical History - Genetic risks for disease often missing from patient charts
Medical Malpractice - Doctors, politicians wait to see if plan works
Medicare - CAMC participates in bonus program
Medicare - CMS proposes new rules to pay appropriately for covered drugs
Medicare - Coverage boosts disease screening for previously uninsured adults
Medicare - Federal funding preserved for hospital pharmacy residencies
Medicare+Choice - Enrollees face continued cost increases in 2003
Medulloblastoma - Cancer research center reports that retinoids kill childhood brain tumor cells
Memory T Cells - Killing is much more efficient than previously thought, upon virus re-exposure
Meningitis - CIE, LA are best tests for pneumococcal antigen detection
Meningitis - West Nile possible, but not probable, cause of aseptic meningitis
Menopause - Grape components lower triglycerides and cholesterol levels in menopause models
Mental Health - APOE genotype joins fetal or neonatal malnutrition as a risk for schizophrenia
Mental Health - Stress moderation model variables provide clues to surgery-related psychology
Mental Health - Structure of schizophrenia-linked gene characterized
Mental Stress - Stress can affect heart rate, NK cell numbers, and subsequent cytokine release
Mergers and Acquisitions - Baptist Health to purchase HealthSouth Doctors' Hospital
Mergers and Acquisitions - Community Health Systems acquires hospital in Petersburg, Virginia
Mergers and Acquisitions - FTC clears Biogen merger
Mergers and Acquisitions - Gen-Probe announces acquisition
Mergers and Acquisitions - Genesis Bioventures announces merger
Mergers and Acquisitions - Home health nursing company acquires home care agencies
Mergers and Acquisitions - Letter of intent signed for merger with diagnostics company
Mergers and Acquisitions - Pharmaceutical research company buys Clinical Pharmacology Associates
Mergers and Acquistions - InnaPhase finalizes acquisition of laboratory automation operations
Metastatic Cancer - Interferon-gamma suppresses S100A4 transcription
Microfluidic Device - Microfluidic device can be programmed for adsorption and release of proteins
Microfluidics - Big pharma orders make for successful commercial launch for Dynaflow
Middle Ear Imaging - MRI of the ear is important for preoperative work-up and diagnosis
Midwifery - Study shows that midwives provide equivalent maternity care for less money
Migraine Headache - Screener found highly reliable in undiagnosed patients
Minority Health - Hemoglobin levels affect outcomes in pregnant African-American adolescents
Molecular Biology - Scientists report why taste and smell differ among individuals
Monkeypox - Researchers to take blood samples from victims for study
Morphogenesis - Class 3 semaphorins mediate vascular growth through integrin inhibition
Mosquito-borne Disease - Aedes albopictus mosquitos do not spread dengue virus
Mosquito-borne Disease - Maize pollen improves Anopheles development
Multicellular Spheroids - Thermo-reversible gelation polymer is very useful for three-dimensional cultures
Multiple Myeloma - Myeloma cell contamination minimal in melphalan-mobilized stem cell grafts
Multiple Myeloma - Thalidomide has been found to be effective for relapsed or refractory myeloma
Mutagenesis - Baculovirus expression vector system allows mutant actin protein studies
Mutagenesis - Deletion in endocytic receptor gene Endo180 impairs collagen uptake
Mutagenesis - Enzyme changes cause different abnormalities in oocytes and bone marrow cells
Mutagenesis - SOX9 gene mutation effects are not necessarily linked to XY sex reversals
Mutagenesis - Suppressor mutations define Cbp1 protein regions important for mRNA stability
Myocardial Infarction - Antidepressant reduces clotting factors after heart attack
Myocardial Infarction - FDA clearance granted to market defibrillator
Myocardial Infarction - Healing the heart with stem cells
Myocardial Infarction - Preliminary results of phase III PRIMO-CABG trial reported
Nasal Reconstruction - Results vary for nasomaxillary epithelial inlay skin graft for saddle nose
National Health Insurance - Thousands of doctors support proposal of single-payer system
National Healthcare Insurance - Louisiana joins push against federal insurance regulation
Neonatology - A modified variance index provides clues about preterm infant development
Neurodegenerative Disease - Scientist links brain disorders to tradition of eating bats
Neurological Activity - CART peptides can act as psychostimulants and reduce some cocaine effects
Neurology - Early endosomes carry nerve growth factor retrograde signals
Neurology - Stroke group announces new program in Dallas
Neuropsychiatric Drugs - Phase I clinical testing of ACP-103 complete
Neuroscience - Hoxb1-expressing neural crest cells play key role in glia development
Neuroscience - Gli2 required for Shh signaling and oligodendrocyte maturity in spinal cord
Neuroscience - MCK-driven dystrophin ameliorates muscular dystrophy in murine fast muscles
Neuroscience - Phosphorylation of calsenilin at Ser63 regulates its cleavage by caspase-3
Neuroscience - RhoG activates Rac1 by interaction with Dock180-binding protein Elmo
Neuroscience - Serial analysis of gene expression provides insight into nervous system
Neurotransmission - The central portion of Bassoon is involved in synaptic targeting, CAZ anchoring
Non-Hodgkin Lymphoma - Delaying chemotherapy could be best treatment option
Nutrition - Cereal maker cites study: Eating breakfast shown to help manage weight
Nutrition - Eating fish may lower heart rate, reduce risk of sudden death
Nutrition - Peanuts that keep hearts healthy on way to grocery stores
Obesity Risk Factor - Children just as likely to choose toys as candy on Halloween
Obesity Therapy - Exendin-4, a GLP-1 receptor agonist, suppresses food intake in rats
Obesity Therapy - Inverse agonism provides insight into obesity control
Obesity Therapy - Medicare and Medicaid pay half of costs for overweight and obesity
Obstetrics - Delaying treatment for an ectopic pregnancy is unethical
Obstetrics - Factors influencing choice of prenatal genetic screening by Israeli women identified.
Obstetrics - Leptin and hCG modulate new vessel growth at the maternal/fetal interface
Obstetrics - Lifestyle changes aid pregnant women with nausea and vomiting
Obstetrics - Monoamine transporters are involved in several reproductive processes
Obstetrics - Physical activity during pregnancy improves psychological well-being
Obstetrics - Taking painkillers during pregnancy increases risk of miscarriage
Obstructive Sleep Apnea - Hyoid myotomy with suspension under local anesthesia is safe and effective
Oncogenesis - Collagen XVII expression is reduced, then increased en route to oral cancer
Oncogenesis - Host angiotensin II type 1 receptor signals foster tumor angiogenesis
Oncology - Assay sensitivity sways the results of gene distribution analysis
Oncology - COX-2 causes prostaglandin E2 to modulate pancreatic cancer angiogenesis
Ophthalmic Therapy - Company announces submission of second Vitrase NDA to the FDA
Oral Lichen Planus - Infiltrating CD8+ T cells express CCR5, CXCR3 and their chemokine ligands
Osteogenesis - Hydroxyapatite particles promote osteogenesis
Osteoid Osteoma - Tibialis spastic varus foot can be caused by osteoid osteoma of the calcaneus
Osteoporosis - Ten surprising facts about bone health every woman should know
Osteoporosis - Therapy that prevents bone loss also reverses cholesterol transport
Outsourcing - South Carolina hospital selects business office outsourcer
Ovarian Cancer - Autoschizis is the principal form of cell death from in vitro vitamins
Ovarian Cancer - Bcl-2 down-regulation is a novel mechanism of paclitaxel resistance
Ovarian Cancer - Transcriptional and transductional targeting improve gene delivery to ovaries
Pain Management - Well-designed trials are needed to determine management of opioid side effects
Pain Medicine - Compound that acts on peripheral receptors may be promising treatment
Pain Medicine - First Flexogan order delivered to Canadian retailer
Pain Medicine - Study: Patient-controlled analgesia in hospitals must be made safer
Pancreatic Cancer - Novel targets for aberrant methylation in pancreatic carcinoma found
Pancreatic Islets - Islet volume increased while islet number remains unchanged in ob/ob mice
Pancreatitis - Acute pancreatitis can occur during painful sickle cell vaso-occlusive crisis
Pancreatitis - Mutation in SPINK1 gene linked to idiopathic pancreatitis in Italian patients
Parasitic Disease - Schistosomiasis symptoms in Nigeria include gynecological manifestations
Parasitology - Trypanosomes lacking pre-mRNA, gRNA still form functional RNA-editing complexes
Parkinson Disease - New drug reduces advanced disease symptoms
Parkinson Disease - Some over-the-counter pain relievers may reduce risk
Patents - Patent pending for antibodies to treat solid organ, cell transplant rejection
Pathogenic Microorganisms - Burkholderia cepacia complex and other pseudomonads are phage-infectable
Patient Safety - Results of utilization management and patient safety study released
Pediatric Endosurgery - Port-site recurrence of malignancy is rare after pediatric endosurgery
Pediatric Radiology - Causes of lower-extremity bowing must be distinguished for proper management
Pediatrics - Groups collaborate in development of pediatric core measures
Personnel - Anderson joins scientific advisory board at cancer drug firm
Personnel - Bernard Questier becomes chief business officer of drug discovery company
Personnel - Buccal drug delivery company hires GunnAllen Financial as advisor
Personnel - Daniel Levitt named VP, chief medical officer of biopharmaceutical company
Personnel - Dr. Farkad Ezzet joins science/IT consulting firm
Personnel - Durrant named president of pediatric drug firm
Personnel - First Coast Service Options announces new medical director
Personnel - Martone appointed head of medical affairs at pharmaceutical firm
Personnel - McClanathan named VP for behavioral health firm
Phagocytosis - Bacterial threat must be gauged during recognition, destruction by macrophages
Pharmaceutical Care - Pharmacist-physician partnership reduces healthcare costs, bad drug interactions
Pharmaceutical Marketing - Physicians using online marketing content, spending less time with sales reps
Pharmaceutical Research - NIH awards grant to Florida A&M
Pharmacokinetics - FDA incentive program improves study of medications for children
Pharmacy - Web-based self-assessment tool helps pharmacy managers improve quality
Pharmacy Management - Kodak to provide service and support to Parata customers
Photodynamic Therapy - Sulfonamide derivatives of porphycene are candidates for treating nasal cancers
Physician Compensation - Several specialties saw decline in 2002
Physiology - Findings in frog oocytes may help study of chromosomes
Plasmodium Falciparum - Study reveals genetic activity of key step in malaria parasite's cycle,
Pneumococcal Vaccine - 23-Valent polysaccharide pneumococcal vaccine not effective in Navajo adults
Prader-Willi Syndrome - Surgery successful in morbidly obese Prader-Willi syndrome patient
Pregnancy Complications - Hormone imbalance and anti-thyroid antibodies may cause postpartum depression
Pregnancy Complications - Placental villotrophoblastic pulmonary emboli can occur following abortion
Pregnancy Tests - Human chorionic gonadotropin is used to test pregnancy but has complications
Preventive Medicine - Macrophage migration inhibitory factor acts in septic shock, may be good target
Prion - Small interfering RNAs inhibit pathological prion protein accumulation
Product Marketing - Imaging company establishes direct sales in Europe's largest markets
Prostate Cancer - Beta-catenin induces hyperplasias and squamous transdifferentiation
Prostate Cancer - Chronic prostatitis may increase risk of BPH and prostate cancer
Prostate Cancer - Chronic zinc oversupply may play a role in prostate carcinogenesis
Prostate Cancer - Drug that mimics vitamin D hormone may boost effectiveness of treatment
Prostate Cancer - Gene profiling and clinical data can predict prostate cancer recurrence
Prostate Cancer - Improvements in radical prostatectomy yield better results
Prostate Cancer - Osteoporosis needs to be managed in men with prostate cancer
Prostate Cancer - Rare MSR1 mutations related to increased prostate cancer in African-American men
Prostate Inflammation - Chronic pelvic pain syndrome could be produced by pressure, nerve aggravation
Proteomics - Egr-1 expression elevated during hyperoxia
Proteomics - late expression factor-8 gene necessary for optimal baculovirus function
Proteomics - Analysis of E. coli W3110 expressing heterologous sigma factor reported
Proteomics - Annexin I interaction "unmasked" from structure of apo-S100A11
Proteomics - Bax and Bak localize to endoplasmic reticulum to initiate apoptosis
Proteomics - Casein kinase 2 is found in brain cell extracts; it binds occludin
Proteomics - FMRP interacting protein shows intracellular localization
Proteomics - Human protein TIN2 stimulates interactions between telomeric DNA tracts
Proteomics - Increase in NO production by bradykinin mediated by protein kinase A pathway
Proteomics - Oxidative stress induces 1-cys peroxiredoxin expression in lung cells
Proteomics - Phosphinic acid-based MMP-13 inhibitors spare MMP-1 and MMP-3
Proteomics - Proteasome-interacting motif found in ubiquitin-like domain of parkin
Proteomics - Researchers search for new cyclic AMP-binding proteins
Proteomics - Sum1 and Ndt80 proteins compete for binding to sporulation element sequences
Proteomics - The true bioactive conformation of anginex is the beta sheet
Proteomics - Up-regulation of elastin gene expression related to increase in transcription
Pseudomonas Syringae - Leading bacterial pathogen is sequenced
Psoriasis - FDA gives green light to U.S. phase I clinical trials for Psoraxine
Psoriasis - Treatment passes Phase II clinical trials
Psoriasis Research - VitD3 downregulates CXCR2, thus inhibiting keratinocyte proliferation
Public Health - Death rate from heart disease improving, but is still higher among black Americans than white
Public Health - Illiterate and poor in Brazil have lower life expectancy
Public Offering - Biotech company announces common stock offering, second quarter results
Public Offering - MRI pharmaceutical company announces pricing of 4,300,000 shares of common stock
Pulmonary Tuberculosis - Adjunctive interleukin-2 does not improve anti-TB treatment efficacy
Quality Assurance - Critics say call center's staff unqualified
RNA Research - Reverse Hoogsteen base pair 54-58 important for tRNA function
RNA Research - Translational efficiency helps regulate expression of RNA binding protein
Rabies - Rabies reported among infrequently affected mammalian carnivores in U.S.
Radiology - Beer-derived beta-pseudouridine protects against radiation-induced chromosome damage
Radiotoxicity - Aegle marmelos extract prevents radiation damage in blood cells
Receptor Signaling - Different adapter proteins help create different microbe-specific TLR signals
Receptor Signaling - Toll-like receptor 4 has MyD88-independent pathway for inducing interferons
Receptor Signaling - Toll-like receptor signaling is dependent on adapter proteins such as MyD88
Recurrent Breast Cancer - Whole-body PET imaging can detect distant metastasis in breast cancer
Regulatory Issues - FDA pledging get-tough stance with drug over-promotion
Reimbursement - PET equipment supplier comments on proposed APC rates for 2004
Renal Artery Aneurysm - Nephrectomy, ex vivo repair, autotransplantation are safe, successful
Reporting - Activists oppose state proposal to report names of HIV patients
Reproductive Medicine - "Minisequencing" can improve detection of genetically defective embryos
Reproductive Medicine - Fertility specialists back warnings on human reproductive cloning
Reproductive Medicine - Identification of allele drop-out risk factors may aid single-gene disorder PGD
Reproductive Medicine - Novel PGD strategy improves muscular dystrophy diagnosis
Research Funding - Breast, prostate cancers focus of new Cancer Society research professorships
Research Funding - Lipids get the spotlight in new NIGMS "glue grant"
Respiratory Disease - Nasal vaccine may increase protection
Respiratory Medicine - Both gender and race influence nasal breathing during exercise
Respiratory Syncytial Virus - Respiratory syncytial virus fusion inhibitor escape mutants characterized
Restenosis - Happy Valley Medical strikes deal to evaluate Ceracor
Rheumatology - Propolis has stronger effects against IL-1 beta in cartilage than indomethacin
SARS - Did rats spread disease in apartment complex?
SARS - Virus will appear again, as will other viruses incubating in "Pandora's boxes"
Sales - Genesis Technology launches drug registration program with U.S. sales force
Schizophrenia - A treatable form of the psychosis was found in Hashimoto thyroiditis patient
Schizophrenia - Illness could cause patients to forget their medication
Schizophrenia Therapy - Mood stabilizers do not affect GSK-3 beta protein levels or GSK-3 activity
Sepsis - NF-kappa B increases occur with organ failure; targeting it may reduce risk
Sexually Transmitted Diseases - Pregnancy centers initiate program to reduce spread of STDs
Sexually Transmitted Diseases - Report finds low condom use, HIV testing in NYC
Sleep Disorders - Report tells older Americans how to fight sleeplessness
Slide Adhesive - Novel microscope slide adhesive for poorly adherent tissue sections is developed
Smallpox - Vaccine provides lifelong immunity
Smallpox - Voluntary shots may not protect
Smallpox Vaccine - Encephalitis is complication of smallpox vaccination
Smallpox Vaccine - Many aspects of smallpox vaccination reviewed
Solid Tumors - Manipulation of the vasculature with TNF improves response
Spinal Disorders - FlexiCore Intervertebral Disc clinical trial begins
Staffing - Small hospitals struggling to recruit, retain pharmacists
Statistics - "Diamond graph" corrects long-standing errors of 3-D bar graphs
Stem Cell Research - Bone marrow cells aid repair of necrotic renal tubules
Stem Cell Research - Bone marrow derived cells could heal organs through wound entry
Stem Cell Research - Diclofenac is toxic to neural stem cells
Stem Cell Research - Hypoxia enhances bone marrow hematopoietic cell activity
Stem Cell Research - Novel P2Y receptor regulates primitive hematopoietic cell activity
Stem Cell Research - Slug transcription factor needed for SCF/c-kit-mediated stem cell radioresistance
Stem Cell Research - TCRbeta enhancer activity characterized in T-cell progenitors
Stem Cell Transplantation - Airflow obstruction common after myeloablative stem cell transplants
Stem Cell Transplantation - Common lymphoid progenitors enhance immune recovery in stem cell graft recipients
Stem Cell Transplantation - Donor DNA chimerism monitoring useful in high-risk stem cell graft recipients
Stem Cell Transplantation - Donor memory T cells do not induce graft-versus-host disease
Stem Cell Transplantation - GVHD, glucocorticoid treatment impair IPC recovery in stem cell recipients
Stem Cell Transplantation - Murine hematopoietic stem cells engraft with near-absolute efficiency
Stem Cell Transplantation - Proteasome activity underlies alloimmune response to HA-3 antigen in stem cell recipients
Stem Cells - First U.K. line generated
Stem Cells - Scientists find that stem cells in the bone marrow become liver cells
Stock Market - Biotech firm reports conditional continued listing on NASDAQ SmallCap
Stock Market - Infectious disease-focused company approved for AMEX
Stock Sale - Biopharmaceutical company raises $2.7 million in private placement financing
Streptococcus - Gene linked to Streptococcus pyogenes in asymptomatic carriers
Stroke - Brain patterns the same whether doing or just watching
Stroke - Penicillin may help prevent strokes in the elderly
Substance Abuse - Legal hallucinogen a dangerous "roll of the dice," warns expert
Substance Abuse - Researchers urge advances in methamphetamine abuse treatment
Suicide - Parents may be less likely to take their own lives
Suicide - Same-sex twins have lower risk than general population
Systemic Lupus Erythematosus - A wide variety of treatments being researched for lupus are more targeted
T Cell Function - CD30 is not only in lymphoma, it is an important regulator of T cell functions
T-Cell Activation - Rho kinase is involved in structural and related activation functions of T cells
T-Cell Epitopes - Proteasomal cleavage sites of proteins for cytotoxic T cells may soon be fully predictable
Targeted Therapy - Complement inhibitor-CR fusion proteins inhibit complement activation better
Technology - DNA beats human challenger in tic-tac-toe
Technology - Hardware, software will enable immunology collaboration
Thoracic Cancer - Spinal cord circulation is an important consideration for thoracic surgeons
Thrombin Inhibition - Ximelagatran is safe given twice daily in a fixed dose regimen
Thromboembolism Risk - Thrombosis risk varies according to primary tumor site
Thrombogenesis - Beta-2-glycoprotein I is higher in lupus, antiphospholipid syndrome macrophages
Thromboprophylaxis - Are patients with cancer receiving adequate thromboprophylaxis?
Thromboprophylaxis - Dalteparin reduces the risk of recurrent thrombosis in cancer patients
Thromboprophylaxis - Some cancer patients do not receive adequate treatment for thrombosis
Thromboprophylaxis - There is an expanding role for antithrombotic therapy in cancer patients
Thrombosis - Drug-coated red blood cells destroy blood clots from within
Thrombosis - Inhibitors of tissue factor VIIa complex designed as antithrombotic drugs
Thrombosis - Thrombosis risk is higher due to increased apoptosis during treatment
Thyroid Cancer - Using cytology with histology has practical predictive value
Total Hip Arthroplasty - New multilayer coating system improves strength of the cement metal bond
Total Joint Arthroplasty - Melagatran/ximelagatran effective in preventing VTE after orthopedic surgery
Transplant Medicine - Absolute lymphocyte count recovery at 30 d associated with CD34+ graft survival
Transplant Medicine - Complement C4d in graft capillaries may mean rejection; it may be controllable
Transplant Medicine - Homograft endocarditis can be caused by Rhodotorula mucilaginosa
Transplant Medicine - Researchers developing new ways to store tissue, organs
Transplant Medicine - Study to rate methods of kidney storage
Transplant Risk - Intestinal transplant recipients can develop calicivirus enteritis
Trends - Devices and prescription drugs driving growth in U.S. pain management market
Trends - Early-stage pharmaceuticals: R&D spending doubles, NDAs plummet
Tuberculosis Diagnosis - MRI may improve osteoarticular TB diagnosis
Tuberculosis Enzymology - Mycobacterial RecA intein acts as DNA-, Mn2+-dependent ATPase
Tuberculosis Genomics and Genetics - DNA repair gene mutations may improve mycobacterial adaption
Tuberculosis Therapy - Mangosteen-derived agents have potent anti-TB activity
Tuberculosis Vaccine - Recent progress in development of vaccines against tuberculosis reviewed
Tumor Suppressor Gene - Identifying Rb function loss may help researchers understand tumor development
Type 2 Diabetes Therapy - Management of obese diabetic patient discussed
Type 2 Diabetes Therapy - Thiazolidinediones play increasing role in metabolic syndrome therapy
Umbilical Cord Blood - Differences identified in T- and B-cell activity from adults and neonates
Upper Airways - Pain, itch, and perhaps other nociceptive nerve types exist in the upper airway
Urban Pollutants - Diesel fumes in particulate air pollution linked to increased atopy and allergy
Ureaplasma - Ureaplasma multiple banded proteins exhibit phase-shifting mechanism
Urinary Tract Infection - Crystallization, calculus formation depend on type of Proteus endotoxin
Urinary Tract Infection - Toll like receptors and IL-8 receptors are involved in disease pathogenesis
Urogynecology - Moderate cystocele patients are the best candidates for four-corner correction
Urologic Symptoms - Prostatitis and interstitial cystitis may have similar symptoms
Urology - A new animal model will further the study of stress urinary incontinence
Urology - Female urethra perception threshold evaluations yield valuable data
Utilization - Aging boomers drive up doctor visits
Vaccine Adjuvant - Mixture of CpG oligodeoxynucleotides may be needed for effective vaccine
Vaccine Delivery - Bacillus spores show promise for vaccine delivery
Vaccine Development - Effort to develop vaccines against helminth diseases reviewed
Vaccine Efficacy - HIV-1-infected children have impaired immunological memory
Vaccine Efficacy - Implications of genetic traits on vaccine efficacy outlined
Vascular Medicine - The matrix protein Del-1 initiates angiogenesis in ischemic tissues
Vault Prolapse - Burch procedure with abdominal sacrocolpopexy is less effective than Burch alone
Vector Development - Better gene expression can be attained with modified adeno-associated virus
Vector Development - Polyethylene glycol FGF2 conjugates retarget adenoviruses to select domains
Vector-borne Disease - Heterologous flaviviruses alter the outcomes of human yellow fever infections
Vectors - Fundamental patent gained for lentiviral gene therapy technology
Viral Epidemiology - Hepatitis B virus genotypes on India's islands arrived with penal settlers
Viral Hepatitis - GBV-B infections in marmosets closely resemble human hepatitis C virology
Virology - Combinatorial approaches enhance the selection of receptor-specific vectors
West Nile Virus - Clinical trial cleared for NeuGene against virus; financial results reported
West Nile Virus - Vaccine said to be effective in mice
Wound Care - Nutritional and pharmacological strategies can enhance wound healing
Wound Care - Ultrasound aids wound bed preparation of chronic wounds
Wound Repair - Duke investigators develop a clinical model of dermal wound angiogenesis
Wound Treatment - V.A.C. Therapy GranuFoam Heel Dressing launched at APMA meeting
Yttrium-90 - Company improves global security of isotope supply
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