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Allergic Rhinitis
Mast cell product-antagonizing is short-term treatment, long-term solutions needed
September 1st, 2003
Allergic rhinitis treatment has been short term, based on mast cell product reduction; soon longterm therapy may be possible. "Mast cells not only function as effector cells, but also influence nearly every other cell involved in causing allergic rhinitis. Mast cell-derived mediators such as histamine, bradykinin, tryptase, and the arachidonic acid derivatives produce the symptoms of the early phase reaction of allergic rhinitis and also attract and activate other leukocytes involved in the late phase reaction," scientists writing in the journal Current Allergy and Asthma Reports report. "In addition, activated mast cells are known to secrete...
Source: Health & Medicine Week (2003-09-01)
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