Endocrinology
Hormone replacement has no effect on the bladders of ovariectomized rats
Published in Health and Medicine Week, September 1st, 2003
"The authors quantified the collagen and elastic fibers in the bladder wall of ovariectomized rats with and without estradiol replacement. This study was conducted on 60 3-month-old Wistar rats," investigators in Brazil reported.
"Group 1 remained intact; group 2 underwent bilateral ovariectomy and were sacrificed after 30 days; group 3 were sham operated and sacrificed after 30 days; group 4 had a bilateral ovariectomy and after 30 days were started on subcutaneous injections of 17beta-estradiol (10 microgram/kg body weight) for 90 days; group 5 were sham operated and after 30...
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