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Health & Medicine Week

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Anorexia Nervosa



Genes showing differential expression in anorexia mutant mouse identified



September 1st, 2003

Genes showing differential expression in the anorexia mutant mouse model have been identified.

According to published research from South Korea, "Differential display (DID) PCR was applied to identify genes regulated by anorexia (anx) in mouse brain. Of the four apparently differentially expressed genes, three (H2-H4) had high homology with known genes such as apoptotic protease activating factor I (Apaf 1), adenylate cyclase 6 (Adcy 6), and myelin proteolipid protein (PLP). H1, designated as HIPA1, had a homology with unknown function gene fragments."

"Northern blot analysis confirmed HIPA1 expression induced by anorexia," reported Hong Sung...


Source: Health & Medicine Week (2003-09-01)

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