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Antifungal Research
Gallerimycin, a moth-derived antifungal peptide, isn't active against yeast
September 1st, 2003
A new antifungal discovered in wax moth, gallerimycin, is not active against yeast. According to published research from Germany, "A novel defensin-like peptide was identified in the greater wax moth, Galleria mellonella. It was discovered in a hemocyte cDNA bank enriched with transcripts upregulated after immune challenge via subtractive hybridization and suppressive PCR. "The deduced amino acid (aa) sequence of the defensin-like peptide exhibits similarities to the antifungal peptides drosomycin from Drosophila melonogaster and heliomicin from Heliothis virescens. Therefore, it has been termed gallerimycin. Upregulation of...
Source: Health & Medicine Week (2003-09-01)
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