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Antiviral Therapy
Novel DSTP derivative inhibits growth of HIV and herpesviruses
September 1st, 2003
A novel DSTP derivative strongly inhibits the cellular activity of HIV and a variety of herpesviruses. According to a study from Germany, "N,N'-bisheteryl derivatives of dispirotripiperazine (DSTP) are a novel class of antiviral compounds with some of their representatives very effectively inhibiting the replication of herpes simplex virus type 1 (HSV-1) in cell culture." "Using one representative of these compounds, the N,N'-bis(1-oxido[1,2,5]oxadiazolo[3,4-d]pyrimidin-7-yl)-3,12-diaza-6,9-diazonia(5,2,5,2)dispirohexadecane dichloride (DSTP 27)," M. Schmidtke and coauthors at the University of Jena "further tried to elucidate the molecular...
Source: Health & Medicine Week (2003-09-01)
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