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Leishmaniasis

 Leishmania major chromosome 3 contains two gene clusters

Published in Health and Medicine Week, September 1st, 2003

Leishmania major chromosome 3 contains two long convergent polycistronic gene clusters separated by a tRNA gene.

According to a study from the United States and England, "Leishmania parasites (order Kinetoplastida, family Trypanosomatidae) cause a spectrum of human diseases ranging from asymptomatic to lethal. The {{approx}}33.6 Mb genome is distributed among 36 chromosome pairs that range in size from {{approx}}0.3 to 2.8 Mb."

"The complete nucleotide sequence of Leishmania major Friedlin chromosome 1 revealed 79 protein-coding genes organized into two divergent polycistronic gene clusters with the mRNAs transcribed towards the...

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