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Asthma Therapy
Nramp gene determines efficacy of mycobacteria-based asthma treatment
September 1st, 2003
The human Nramp gene determines the efficacy of mycobacteria-based asthma treatment. "Genes controlling antibacterial resistance may be important in the hygiene hypothesis, which states that lack of bacterial infections during childhood would favor development of allergic disease," scientists in the Netherlands explained. With this in mind, J.J. Smit and colleagues at the University of Utrecht examined "whether Nramp1 (Slc11a1) alleles, which determine susceptibility (Nramp1(s)) or resistance (Nramp1(r)) to intracellular bacteria, affect the efficacy of heat-killed Mycobacterium vaccae in the treatment of...
Source: Health & Medicine Week (2003-09-01)
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