Malaria Pathogenesis
P. falciparum hastens red blood cell senescence
Published in Health and Medicine Week, September 1st, 2003
"Red blood cells infected with Plasmodium falciparum (IRBCs) undergo changes primarily in their membrane composition that contribute to malaria pathogenesis," researchers in Italy explained. "However, all manifestations (eg, anemia) cannot be accounted for by IRBCs alone."
"Uninfected erythrocytes (URBCs) may play a role, but they have been under-researched," noted F. Omodeo-Sale and colleagues at the Istituto di Fisiologia Generale e Chimica Biologica 'Giovanni Esposito' in Milan, who investigated "changes in the erythrocyte membrane that could contribute to URBC reduced life span and...
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