Health & Medicine Week
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of Health & Medicine Week
We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.
Autoimmune Disease
Some MG seronegative patients may be MuSK antibody positive
September 1st, 2003
MG seronegative patients may be atypical and some can be identified by MuSK antibody positivity. "Serum antibodies to muscle specific receptor tyrosine kinase (MuSK) were detected in 12/32 patients with generalized seronegative MG. All were women, with onset between ages 21-59. Seven had prominent neck, shoulder, or respiratory muscle weakness, and little or delayed ocular muscle involvement," scientists in the United States report. "The response to cholinesterase inhibitors was variable, and electromyographic findings suggested myopathy in several. None improved after thymectomy. All patients improved after plasma exchange, and most had a good...
Source: Health & Medicine Week (2003-09-01)
|
