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Stem Cell Transplantation

Delayed G-CSF stem cell mobilization after chemotherapy may be feasible

Published in Health and Medicine Week, September 15th, 2003

Delayed initiation of G-CSF after chemotherapy does not appear to affect the outcome of stem cell mobilization.

In a recent study, scientists in the United States "retrospectively compared the effects of two time points of G-CSF (Filgrastim) introduction for PBSC mobilization in 45 children with different malignancies."

"Seventeen patients received the first G-CSF dose on day 2 or 3 following chemotherapy (group 1)," while "twenty-eight patients received a 'flexible' G-CSF injection schedule when the G-GSF was started at the time of the first platelet count rise during post-chemotherapy recovery phase (group 2)," according to I. Dolgopolov and...

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