Health and Medicine Week

Fibromyalgia - Study identifies three distinct clusters of the disease

Sclerodoma - Study offers genetic clues to causes of mysterious skin disease

Circadian Rhythm - Research builds link between sleep, cancer progression

Fitness - Fire fighters at high risk for heart attack

Injury Prevention - Health education can reduce leading cause of death among children

AIDS Policy - Analysis gives positive report on Nigerian president in fight against AIDS

AIDS Therapy - Anti-HIV drug continues development through pharmaceutical collaboration

Abortion - Manual, low-tech method for second trimester abortions found safe and effective

Abortion - Michigan bill would ban certain late-term procedures

Acute Coronary Syndrome - Second patient receives CardioPass coronary artery bypass graft

Acute Myocardial Infarction - Anemia drug may help lessen effects of heart attack

Acute Myocardial Infarction - Delay to care takes away angioplasty's benefit

Acute Otitis Media - Surprise: antihistamines may do more harm than good

Addiction Medicine - Drug abuse in the pregnant female creates a risk for peripartum complications

Address Correction - IL-18BP can bind IL-18, reduce IFNgamma effects of contact hypersensitivity

Adolescent Health - Study says parents are key to pregnancy desire among black teens

Advanced Breast Cancer - Anastrozole is preferable to tamoxifen in efficacy and tolerability

Adverse Effects - Transfusion-related acute lung injury can occur with IL-2, platelet transfusion

Aging - Driving performance declines with dementia and age

Aging - Minorities, women accept growing older more gracefully

Aging - Most of U.S.'s oldest old lack some basic assistance

Allergic Inflammation - Eosinophils have cysteinyl leukotriene receptors; one may be internal

Allergy - Chewable tablet and suspension syrup available to treat allergy and cold

Allergy Medicine - Anaphylaxis to pine nuts is not linked to other nut or pine pollen allergy

Allergy Medicine - Celiac disease is complex, involving genetic and nongenetic input to form

Allergy Medicine - Dexamethasone regulates interleukin-5 post-transcriptionally

Allergy Medicine - Early sesame sensitivity may include anaphylaxis; some children outgrow it

Allergy Medicine - Fc epsilon RI alpha-chain polymorphism -66T/T is associated with allergy

Allergy Medicine - More boys have asthma; more originally nonatopic girls get asthma as adults

Allergy Medicine - Persistent atopic dermatitis, asthma development in children is linked to mites

Allergy Medicine - Study shows link between antibiotics and allergies, asthma

Alopecia - Hair loss and alopecia can occur in women too, may be due to immune disease

Alopecia - Studies show cloned anti-sex hormone molecule cures baldness

Alzheimer Disease - Abeta precursor protein reacts with a recessive hypercholesterolemia protein

Alzheimer Disease - Alzheimer disease sample bank collection launched for genetic research

Alzheimer Disease - CSF markers useful for diagnosis in Alzheimer disease

Alzheimer Disease - Caregivers refuse medications when patient's quality of life threatened

Alzheimer Disease - FDA advisory committee recommends approval of Namenda

Alzheimer Disease - New ELISAs detects markers of neurodegenerative disease

Alzheimer Disease - New research technique provides unique glimpse into mind-disabling disease

Alzheimer Disease - Spheron discovery bolsters company's AD therapeutic pipeline

Ambiguous Genitalia - Surgical management of ambiguous genitalia discussed

Amyloidogenesis - Heparan sulfate proteoglycans may aid folding and fibril formation of amyloids

Amyotrophic Lateral Sclerosis - Healthy neighbors rescue degenerating motor neurons

Amyotrophic Lateral Sclerosis - New genetics research study under way

Analgesics - Company to reacquire rights to CINOD class of drugs from AstraZeneca

Anesthesia - Anesthetics inhibit high-affinity states of dopamine D2

Angiology - Coronary artery calcium levels linked to coronary heart disease

Angiology - Phase IIIa study of Neutralase in CABG halted

Ankylosing Spondylitis - Enbrel receives positive recommendation from European Committee

Anorexia - NDA submitted to FDA for norgestimate/ethinyl estradiol

Anorexia Nervosa - The Japanese Body Attitude Test doesn't distinguish major factors

Anthrax - Antibodies demonstrate efficacy against anthrax spore challenge

Anthrax - Antidotes to bioterror agent slow to arrive

Anti-Inflammatory Molecules - Chitosan acts on activated macrophage to lower PGE₂ , TNFalpha, increase IL-10

Antibiotics - Amended agreement signed to extend distribution of ciprofloxacin

Antibiotics - Antimicrobials ineffective for NTS eradication

Antibiotics - Azithromycin better tolerated that ABC in ABS patients

Antibiotics - Azithromycin for trachoma control doesn't increase streptococcal resistance

Antibiotics - Linezolid safe for renal damage and hemodialysis patients

Antibiotics - Novel assay aids detection of antibiotics in water supplies

Antibody Refolding -  E. coli oxidoreductases may be useful for immunoglobulin refolding

Anticancer Agents - New platinum-based anticancer agents may be developed in the near future

Anticancer Preparations - Tea, Capsicum mixture shows anticancer activity

Antimicrobial Activity - Green tea catechins can act alone or with antibiotics on Helicobacter pylori

Antimicrobial Resistance - Streptococcal tet(O) gene linked to drug resistance

Antimicrobials - Viomycin biosynthesis gene cluster identified in Streptomyces strain

Antipsoriatic Drugs - Understanding the genetics of psoriasis may lead to more effective therapy

Antisense Oligonucleotide - Patent granted for GEM231

Antiviral Drugs - Human herpesvirus 8 is most susceptible to the antiviral drug cidofovir

Antiviral Therapy - Entecavir reduces hepatitis B virus DNA in the livers of animal models

Apoptosis - Catalysts initiate reactions that cause cancer to self-destruct

Apoptosis - La³⁺, Gd³⁺, Yb³⁺ change mitochondrial membranes, raise ROS level

Arthritis Therapy - Stem-cell transplantation may have limited benefit for RA patients

Arthrobacter - X-ray analysis of ATP-glucomannokinase from Arthrobacter KM reported

Aspirin Therapy - New report shows aspirin lowers risk of a first heart attack by one-third

Asteraceae - Ingestion of essential oils beta-myrcene and limonene can inhibit inflammation

Asthma - Airway scarring can be disrupted by targeting eosinophils

Asthma - Asthma susceptibility loci identified on chromosome 12q

Asthma - Beta-arrestin-2 regulates the development of allergic asthma

Asthma - Hepatitis A exposure lowers risk

Asthma - Some children at risk of respiratory problems when exposed to low-level ozone

Asthma Risk Factor - Obesity is risk factor for newly diagnosed asthma

Atherosclerosis -  Hibiscus sabdariffa extract inhibits development of atherosclerosis

Atherosclerosis - Antril phototherapy is well tolerated in phase I trial

Atherosclerosis - Leptin resistance may cause arterial disease in those with metabolic syndrome

Autoimmune Disease - Immune imbalance restored using prosorba column treatment

Autoimmune Disease - Rheumatoid arthritis patients have autoreactive T-cell subset expressing NKG2D

Autoimmune Markers - Company to develop and supply autoimmune tests for Beckman Coulter

Awards - Researcher wins lifetime achievement award for his efforts to battle leukemia

Bacillus - Amino acid sequences of new subtilisin from Bacillus isolate reported

Bacillus Subtilis -  B. subtilis lipoteichoic acid, LPS, endospores can induce IL-6 in macrophages

Bacillus Thuringiensis - Linear tectiviral plasmid prophage from Bacillus thuringiensis reported

Bacteria - The mitochondrial ornithine transporter characterized

Bacteriology -  Coxiella burnetii express type IV secretion system proteins

Benign Prostatic Hyperplasia - Patent expirations to stall benign prostatic hyperplasia drug sales between 2007-12

Biodefense - Government reports "tremendous progress" in research

Bioengineering - A new fibrin gel model paints a clearer picture of angiogenic mechanisms

Bioengineering - California universities partner to develop implantable electronics

Biomaterial - Company gets FDA clearance of expanded marketing claims for SurgiWrap

Biomimetics - Biomimetic design in microparticulate vaccines reviewed

Biotherapeutic Manufacturing - New clinical bioprocessing facility opened

Bipolar Disorder - Data: Risperdal produces continuous improvement of manic symptoms

Bladder Cancer - Integration of newer biologic agents should be a primary direction of research

Bladder Tumors - New WHO/ISUP classification for TA, T1 bladder tumors reviewed

Blood Product Risk - There is no proof of transmission of vCJD by blood supply, but no good test

Blue-Cell Tumors - Methods other than H&E staining can now distinguish the different blue-cell tumor types

Bone Cancer - Adenovirus-mediated B7-1/Fas chimeric gene transfer destroys osteosarcoma

Botulinum Toxin - Researchers identify botox receptor

Brain Tumors - Adoptive immunotherapy holds promise for effective therapy of malignant glioma

Brain Tumors - There was no correlation between Tc and Tl uptakes by malignant brain tumors

Breast Cancer - Breast cancer incidence and mortality trends in 16 European countries reviewed

Breast Cancer - Data warehousing used to create database for cancer research

Breast Cancer - Differences in activity of Sp3 can determine expression level of AP-2gamma gene

Breast Cancer - Disrupting two cell mechanisms suppresses aggressive disease in mice

Breast Cancer - Docetaxel-epirubicin regimen is effective in poor prognosis breast cancer

Breast Cancer - Evidence-based decision tool reduces adjuvant therapy use in low-severity tumors

Breast Cancer - Exercise lowers a woman's risk for breast carcinoma in situ

Breast Cancer - Extensive vascular formation in a fibrous breast tumor leads to malignancy

Breast Cancer - FDA approves RODEO breast MRI method

Breast Cancer - Foundation launches first virtual advocacy forum

Breast Cancer - Genetic counseling offers much-needed advice for high-risk women

Breast Cancer - High-energy shock waves (HESW) enhance paclitaxel cytotoxicity in MCF-7 cells

Breast Cancer - IL-8 is implicated in the osteolysis associated with metastatic breast cancer

Breast Cancer - MUC1 functions in cross talk between ErbB2 and Writ pathways

Breast Cancer - Massage therapy affect on immune function studied in breast cancer patients

Breast Cancer - Mental adjustment to cancer is a main contributor to psychological distress

Breast Cancer - New breast cancer treatment shows higher anti-tumor activity than competitor

Breast Cancer - New mannequin helps teach women how to differentiate breast lumps

Breast Cancer - New technique fails to detect noninvasive disease

Breast Cancer - Obesity not associated with efficacy of tamoxifen for early-stage disease

Breast Cancer - Peer-counseling helps black women improve quality of sex life after cancer

Breast Cancer - Pre-existing conditions and treatment are related to breast cancer survival

Breast Cancer - Researchers identify a novel growth inhibitor that is downregulated by estrogens

Breast Cancer - Results of Singapore National Breast Screening Program reviewed

Breast Cancer - Routine chest X-ray in the follow-up of breast cancer patients is of little use

Breast Cancer - Stamp raises money for research, but careful accounting needed

Breast Cancer - Study demonstrates improved survival in women treated with Taxotere

Breast Cancer - Study may have implications for aiding understanding of BC risks around world

Breast Cancer - Use of digital images may be justified in visual assessment of breast density

Breast Cancer - Welsh women's comments about breast problems and the care given are evaluated

Breast Cancer - White, Hispanic women might have lower p53 gene mutation prevalence

Breast Cancer Detection - FDA approves ImageCheckerDM CAD

Breast Cancer Risk Factor - Association between fatty acids and breast cancer remains controversial

Breast Cancer Therapy - Anti-HIV CXCR4 antagonists may also inhibit breast cancer

Breast Tumors - Computer-assisted detection of mammographic masses evaluated

Burn Care - Biomedical company to acquire skin cream product

Cancer - Antibody blockade of the Cripto CFC domain suppresses tumor cell growth in vivo

Cancer Cell Killing - Effectiveness of calothrixin A related to ring structure

Cancer Diagnostics - Call issued for early oral cancer detection

Cancer Immunotherapy - Electroporated dendritic cells are powerful cytotoxic T lymphocyte stimulators

Cancer Immunotherapy - Study prompts CMS decision to increase access to high-dose IL-2 treatment

Cancer Mortality - Benzene, exposure threshold factors for evaluating lymphohematopoietic risk

Cancer Therapy - Carboxyamido-triazole interrupts angiogenic stimulation to diminish tumor size

Cancer Therapy - Data from phase I trial of KOS-862 looks positive

Cancer Therapy - FLAG chemotherapy with SCT effective for myeloid metaplasia patient

Cancer Therapy - Laserphyrin recommended for Japanese market approval

Cancer Therapy - Lorus licenses NC 381 and library of clotrimazole analogs

Cancer Therapy - Novartis makes $10 million equity investment after oncogenesis milestone

Cancer Therapy - Phase I/II trial using HuMax-EGFr begins

Cancer Vaccine - Frontier of tumor vaccines has gone from gene therapy to dendritic cells

Cancer Vaccine - Melanoma-associated antigen DNA vaccine invokes anticancer protection

Cancer Vaccine - Structure of mammalian tumor-associated antigen UK114 elucidated

Cancer in Adolescents - Clinical trials involving adolescents with cancer are needed

Cardiac Resynchronization - Heart Failure Society: Evidence supports addition of CRT to future practice guidelines

Cardiac Safety - LifeSignals technology platform launched to address regulatory requirements

Cardiac Safety Monitoring - Cardiac monitoring company secures $1.1M in services for clinical trials

Cardiology - Kv1.5 gene transfer restores 4-aminopyridine-sensitive currents to heart cells

Cardiovascular Risk Factors - Early signs of heart disease detected in asymptomatic individuals

Carotid Artery Disease - Filter-stent combination trial data are reported to be promising

Catheter-related Infections - Micrologix, collaborator, further assess MBI 226 regulatory and market options

Cell Death - Cilostazol prevents tumor necrosis factor-alpha-induced cell death

Cell Line Transfer - MultiCell receives $1.5 million for XenoTech cell transfer

Cell Receptors - SR-PSOX/CXCL16 recognizes all bacteria and coordinates their phagocytosis by APC

Cellular Therapy - Five-year distribution agreement signed for cellular therapy products

Central Pain - CP with primary CNS tumors was higher with spinal cord tumors than brain tumors

Cerebral Aneurysm - Company announces receipt of NIH grant for aneurysm-filler device

Cerebral Palsey - Low and high birth weight increase risk of birth defect

Cervical Cancer - Exploration initiated into new super therapy for cancer

Cervical Cancer - MR imaging is reliable in evaluating carcinoma of the cervix

Cervical Cancer - Pap smear screening among Mexican-American women associated with beliefs

Childhood Immunization - Have parents behaved irrationally towards MMR?

Chronic Heart Failure - Medicare agrees to pay for implanted battery-powered pump

Chronic Hepatitis B - More evidence points to adoptive immunity as a means of clearing hepatitis B

Chronic Hepatitis C - High body mass index heightens risk for nonresponse to therapy for hepatitis C

Chronic Insomnia - Preliminary results reported on phase III indiplon trial

Cirrhosis - Obesity linked to death from liver disease in nondrinkers

Cloning - Aggregation of cloned mouse embryos improves survival rate

Cocaine Addiction - Anticonvulsant drug is promising therapy for drug abuse

Cochlear Implants - Program studies bilingual speech development in children

Collaborations - Agreement made for sales of infectious disease diagnostics in Pakistan and Afghanistan

Collaborations - Agreement signed for use of the ACE system to produce biologics

Collaborations - Aptamers for diagnostics, therapeutic uses targeted as part of alliance

Collaborations - Drug discovery alliance completed

Collaborations - Four-corporation collaboration offers system for gene expression analysis

Collaborations - Gene expression profiling license agreement signed

Collaborations - Genetics company expands pharmacogenomics research collaboration

Collaborations - Licensing agreement expanded for Humira

Collaborations - Licensing agreement signed for gene silencing methodology

Collaborations - Life science software company announces strategic distribution agreement

Collaborations - Novel anticancer drug licensed from Lorus

Collaborations - P&G enters obesity research collaboration

Collaborations - Proteomics drug discovery alliance milestones, progress reported

Collaborations - Reseller agreement signed for bioanalyzer

Collaborations - Strategic partnership created to make new telehealth services available

Colon Cancer - Adenovirus-mediated transduction enhances radiosensitivity in colon cancer

Colon Cancer - Lipoplexes containing interferon genes and poly I:poly C halt metastasis

Colon Cancer - MSI-H colorectal, MSI-L endometrial tumors result in marker for high-risk

Colonography - The unfolded cube projection method enhances the 3D endoluminal display

Colorectal Cancer - Antitumor activity of capecitabine is directly affected by DPD activities

Common Cold - Metabolic agents implicated in asthma and allergy also linked to common cold

Complementary and Alternative Medicine -  Momordica charantia extracts possess antihyperglycemic activity

Complementary and Alternative Medicine -  Terminalia catappa Linn fruits exhibit antidiabetic activity

Complex Disease Investigation - Multiple sclerosis and autoimmune diseases can be approached using new techniques

Congestive Heart Failure - Heart failure patients benefit from triage b-type natriuretic peptide testing

Congestive Heart Failure - Heart failure patients improve medication compliance with Web-based monitoring

Congestive Heart Failure - New insight into heart failure suggests novel drug target

Congestive Heart Failure - Outpatient treatment for congestive heart failure studied in pilot trial

Consumer-driven Health Plans - Skyrocketing healthcare costs prompt change in insurance options

Continuity of Care - Forced health plan switches have adverse affect on patients

Continuity of Care - New definition aims to make concept clearer for researchers

Continuity of Care - Provider continuity associated with lower total healthcare costs

Continuity of Care - Vulnerable patients value ongoing medical relationship more than others

Contraception - New Web site helps expand emergency contraception access

Coronary Artery Bypass - Computer model shows bypass surgery more cost-effective than stents

Coronary Artery Bypass - Sodium nitroprusside reduces cardiac inflammatory reaction and improves function

Coronary Artery Disease - Drug-eluting coronary stent receives private sector reimbursement in France

Corporate Update - Expanded U.S. sites planned by pharmaceutical company

Cystic Fibrosis - Gene mutations may prevent sperm from acting normally

Cystic Fibrosis - Safety and efficacy study planned for potential cystic fibrosis treatment

DNA Damage - DNA damage control in cells exposed to ionizing radiation reviewed

DNA Nanoparticles - Breakthrough reported in non-viral gene therapy

DNA Research - Microfabricated electrophoresis device aids DNA extraction

DNA Technology - New third quarter contracts signed for DNA fingerprint analysis

Dendritic-Cell Function - Dendritic-cell activation by lipopolysaccharide involves participation of Raf1

Dendritic-Cell Function - RNA interference reveals human dendritic cells need NF-kB1 to make IL-12

Dendritic-Cell Vaccine - Genetic tagging shows longevity of antigen-presenting dendritic cells

Dendritic-Cell Vaccine - Highly potent dendritic cell-tumor cell hybrid vaccines developed

Dengue Fever - Dengue fever vaccine best delivered at one year of age

Depression - Analysis of antidepressant studies demonstrate significant efficacy of Effexor

Depression - FDA approves generic nefazodone hydrochloride tablets

Depression - Gene variations alter antidepressant side effects

Depression - New understanding of treatment resistance reached

Dermatology - Interferon-alpha therapy for chronic hepatitis C causes skin color changes

Dermatology - Multiple spindle cell lipomas can occur on the tongue, not just back and neck

Developmental Biology - Sexual orientation "hard-wired" before birth

Diabetes - Biosensor company completes successful in-vitro proof-of-concept studies

Diabetes Genomics and Genetics - Angiotensin-converting enzyme gene increases microalbuminuria risk

Diabetes Genomics and Genetics - Novel phosphoenolpyruvate carboxykinase gene promoter variant found

Diabetes Genomics and Genetics - Zinc-finger gene ZNF236 unlikely to promote diabetic nephropathy

Diabetes Pathogenesis - 1,25-dihydroxyvitamin D₃ completely protects mice against diabetes

Diabetes Pathogenesis - Antioxidant levels lower in adults with the metabolic syndrome

Diabetes Pathogenesis - N-ethylmaleimide-sensitive factor required for exocytosis

Diabetes Risk - Estimated lifetime risk for developing diabetes is high

Diabetes Surgery - Human islet transplants more successful after culturing

Diabetes Therapy - Novel class of hypoglycemic agents identified

Diabetic Retinopathy - New database of eye diseases available for research

Diagnostics -  Burkholderia pseudomallei pneumonia only identified by groEL sequencing

Diagnostics - Celiac disease can be diagnosed by serologic test results; biopsy just confirms

Diet and Nutrition - Altered protein intake may affect calcium metabolism and cause bone loss

Diet and Nutrition - Nut consumption does not increase body weight

Disease Management - New contract adds asthma, COPD, ESRD to existing programs

Drug Abuse - 80% of participants complete online drug abuse treatment

Drug Delivery - European patent granted for aerosol formulations

Drug Delivery - Inhalation treatment for hypertension approved for marketing in Europe

Drug Delivery - Kurve secures development partnership with Italian company

Drug Delivery - Multidose inhaler offers pulmonary drug delivery

Drug Delivery - Tiny plastic particles deliver lifesaving medicine

Drug Delivery - Trojan Horse technique may slow growth of tumors

Drug Development - Chinese herbal medicine may be basis for anti-HIV agents

Drug Development - Lipid agents disrupt mycobacterial actin function

Drug Development - Tiny "test tubes" may aid pharmaceutical R&D

Drug Profiling - MDS collaborates on Pharmotif Solutions for chemogenomics profiling

Eating Disorders - Original EDI scales are reliable for assessing binge eating disorder

Electrocardiography - LifeSync Wireless ECG System receives 510(k) clearance

Embryology - KL-6, a MUC1 mucin, is expressed in normal fetal lung at >23 weeks gestation

Emergency Contraception - Drive to extend rape-victim contraception policy in U.S. slows

Emphysema - Medicare will cover lung volume reduction surgery for certain patients

Endocrinology - Structure of human bactericidal/permeability-increasing protein reported

Endometrial Cancer - Rapamycin inhibits telomerase activity by decreasing the hTERT mRNA

Endotracheal PVC Tubes - Plasticizer DEHP may cause lung disease in infants given endotracheal tubing

Environmental Health - Enzyme activity predictive of quality in mercury-contaminated soils

Environmental Toxins - Possible air pollution-brain cancer link to be studied

Environmental Toxins - Spectators discouraged from watching building demolitions

Enzymology - Inhibitory gene therapy abates the angiogenic character of endothelial cells

Enzymology - Perforin and granzyme B are differentially expressed in chronic hepatitis C

Epidemiology - A sandfly vector survey in Lebanon reveals potential Leishmania transmitters

Epidemiology - Gulf War service-ALS link confirmed

Epidemiology - Sporadic hepatitis E virus cases in Hokkaido, Japan appear to be food-borne

Epilepsy - Drug developed at Hebrew University to undergo Phase III clinical trials

Epilepsy - Epilepsy treatment to be developed through collaborative effort

Epilepsy - Exclusive rights to Gabapentin GR acquired

Epithelial Ovarian Cancer - Head-to-head study shows CAELYX prolongs survival

Epstein-Barr Virus - Epstein-Barr virus nuclear antigen co-localizes with lamin B1 in nucleoplasm

Epstein-Barr Virus - Epstein-Barr virus-encoded EBNA1 self-inhibits antigen presentation

Erectile Dysfunction - New pharmacologic, nonpharmacologic treatments for erectile dysfunction reviewed

Escherichia Coli -  E. coli enterohemolysin can be inhibited most by high density lipoprotein

Escherichia Coli - An Escherichia coli strain was found with 4 microcin, MCC V immunity genes

Escherichia Coli - Curliated E. coli generate proinflammatory fibrinopeptides from fibrinogen

Exercise - Pulmonary function predicts anaerobic exercise performance in cystic fibrosis

Eye Health - Many chronic eye disease patients neglect annual eye exams

Facilities - Company opens new tray manufacturing and assembly facility

Facilities - NIAID funds construction of biosafety laboratories

Facilities - Pharmaceutical company signs lease for new facility

Fancomi Anemia -  Fanca mutations linked to FA identified in mice

Fetal Assessment - Company launches "next generation" hand-held Dopplers

Fibroids - Some hysterectomies may be prescribed unnecessarily

Finance - Acquisition of Q-One Biotech completed

Finance - Consumer healthcare company declares 100% stock dividend

Finance - Contract service company updates outlook for 2003

Finance - Diagnostics company revises 2003 guidance

Finance - Food safety company reports 21% increase in net income

Finance - Genetic discovery tools provider secures $22.5 million in financing

Finance - Genomics analysis company completes $3 million private equity financing

Finance - Hormone maker is approved for listing on the American Stock Exchange

Finance - Imaging company announces extension of loan agreement

Finance - Investment management firm closes $300 million health care venture fund

Finance - LCA-Vision files for public offering of common stock

Finance - Life-sciences company files shelf registration statement

Finance - Orthodontics company reports "turnaround year"

Finance - Orthopedic products company completes private placement

Finance - Periostat maker reports anticipated revenue increase of 22-25%

Finance - Pharmaceutical company announces offering of convertible senior debentures

Finance - Pharmaceutical company announces reverse stock split

Finance - Pharmaceutical company reports loss of $0.01 per share

Finance - Pharmaceutical firm prices public offering

Finance - Stock trading halted pending FDA review of Provigil sNDA

Financing - $6.5M private equity investment made in UK drug discovery company

Financing - Pharmaceutical firm announces US$16.3M financing

Financing - Protein therapeutics company raises $12.5M

Fitness - "Good" chemical, neurons in brain elevated among exercise addicts

Food Allergy - Protein from poultry, legumes can also induce infant enterocolitis syndrome

Food-borne Disease - Hepatitis A outbreak linked to blueberries in New Zealand

Forearm Flap Surgery - Fail-safe drainage procedure successful in free radial forearm flap transfer

Franchise Agreement - Chiropractic USA continues expanding, enters agreements for Texas

Funding - Pathologist awarded $1 million grant to study virus assembly

Gastric Bypass - Obesity surgery resolves or improves diabetes in most patients

Gastroenterology - Circulating IL-8 might be a marker for recurrent gastric cancer

Gastroesophageal Reflux Disease - Endoscopic therapy for gastroesophageal reflux disease reviewed

Gene Deletion - The disruption of endothelial cell-selective adhesion molecule reduces tumors

Gene Mapping - Company awarded $500K Phase II SBIR grant from National Science Foundation

Gene Therapy - HIV-2 vectors suitable for treatment of Parkinson and Fabry disease

Gene Therapy - High-level of polyclonal antibodies generated by genetic immunization

Gene Therapy - Molecular basis for gene vaccines against autoimmune disease developed

Gene Therapy - SIV vectors expressing vMIP-II show promise

Gene Transfer - A new synthetic gene carrier may enhance current options for gene delivery

Gene Transfer - Inhibitors and modification make recombinant baculoviruses efficient vectors

Generalized Anxiety Disorder - Prediction: Five new GAD drugs will arrive to market by 2008

Generic Drugs - Canadian government looking to ease drug restrictions

Genetic Disorders - Better-than-expected prognosis for recessive X-linked myotubular myopathy

Genetic Disorders - Clinical features of complex III deficiency due to BCS1L gene mutations

Genetic Disorders - Novel mutation seen in beta-thalassemia patient

Genetic Disorders - Novel mutations found in infantile onset glycogen storage disease type II

Genetic Disorders - Novel mutations identified in McArdle's disease patients

Genetics - Novartis Institutes for BioMedical Research selects partner for drug validation

Genomics - A novel RNA-specific PCR method detects recombinant virus vector expression

Genomics - A novel single-stranded DNA expression vector generates intracellular enzyme

Genomics - Activity of ABthrax described at ICAAC

Genomics - GlaxoSmithKline licenses computable biological knowledge base

Genomics - Novel genomic software aids ortholog group identification

Genomics and Genetics -  PON1 genotype variations have heightened influence in neonates

Geriatrics - Elderly patients with fecal incontinence have several treatment options

Geriatrics - Several elements are linked with the impaired angiogenesis of aging

Glioma Xenografts - Disabling EGFRvIII needs to be considered if using EGFR for radiosensitization

Grants - Biotechnology company receives grants from NIAID, NIAAA

Growth Phase Antibodies - Cancer proliferation index is higher when using the MIB-1 type of Ki-67 antibody

Gynecologic Cancers - Group issues first annual report on advances in detection, treatment

Gynecology - Calcium deficiency may be linked to premenstrual syndrome

Gynecology - Characterizations of ovarian follicular wave dynamics show varying patterns

Gynecology - Chronic pelvic pain requires a multidisciplinary treatment approach

Gynecology - Endometrial cancers produce angiogenic growth factor genes

HIPAA - Blues of Florida releases plans to accept noncompliant provider claims

HIPAA - Insurer makes provisions for providers who can't meet deadline

HIV Diagnosis - Urine-based HIV-1 test to be studied in Tanzania, Rwanda, Burundi, Botswana

HIV Inhibitor - Boosted saquinavir shows significant safety benefit over boosted Crixivan

HIV Therapy - HIV antiviral platform expanded through development of Thiovir

HIV/AIDS - Lymphocyte HSP70 expression altered during HIV infection

HIV/AIDS Gene Therapy - Latency-inducing gene therapy may be effective for HIV patients

HIV/AIDS Immunology - Plasma levels of B-lymphocyte stimulator rise with HIV disease progression

HIV/AIDS Lipodystrophy - Adipose tissue metabolism characterized in HIV patients

HIV/AIDS Pathogenesis - Apelin-13 interactions with APJ receptor characterized

HIV/AIDS Pathogenesis - Cyclophilin A modulates HIV sensitivity to host restriction factors

HIV/AIDS Proteomics - Cellular internalization of HIV Tat fusion proteins characterized

HIV/AIDS Proteomics - Protease-cleaved Tat needed for efficient HIV reverse transcription

HIV/AIDS Proteomics - Radiation analysis clarifies HIV RT structure

HIV/AIDS Public Health - Antiretroviral DOT improves outcome for drug-abusing HIV+ women

HIV/AIDS Therapy - Definition of virologic failure in HIV drug trials questioned

HIV/AIDS Therapy - E44D and V118I mutations in HIV RT play distinct roles in drug resistance

HIV/AIDS Therapy - Expert GRT assistance improves HIV treatment outcome

HIV/AIDS Therapy - Factors linked to long-term plasma HIV RNA suppression reported

HIV/AIDS Therapy - HIV protease inhibitors may lower vitamin B-12 serum levels

HIV/AIDS Therapy - HIV subtype C mutation confers hypersusceptibility to lopinavir

HIV/AIDS Therapy - HIV treatment interruptions linked to thrombocytopenia

HIV/AIDS Therapy - Mutations in HIV env explained discordant HAART outcome

HIV/AIDS Therapy - Xerostomic agents don't alter salivary gland function in HIV patients

HIV/AIDS Transmission - Carrageenan formulation prevents macrophage trafficking from vagina

HIV/AIDS Transmission - Some HIV phenotypes preferentially transmitted through breast milk

Head and Neck Cancer - E48 real-time quantitative RT-PCR can detect micrometastases in lymph nodes

Head and Neck Cancer - Lifelong follow-up suggested to prevent radiation-induced malignancies

Head and Neck Cancer - Stromal syndecan-1 induction associates with squamous cell carcinoma metastasis

Head and Neck Cancer - The pedicled occipital artery scalp flap can be used to reconstruct neck defects

Head and Neck Carcinoma - SCH66336 is a potent apoptosis inducer and it may suppress the Akt pathway

Health Coverage Tax Credit - Nearly 3,000 unemployed workers in Tennessee eligible for new insurance program

Healthcare Access - Grants awarded to improve access to services for low-income population

Healthcare Access - PNM pulls out of HMO coverage

Healthcare Access - Thailand begins distributing free AIDS drugs to 50,000 sufferers

Healthcare Coverage - Backers of small business plan point to numbers of uninsured

Healthcare Coverage - El Paso residents without insurance weigh on hospitals, doctors

Healthcare Coverage - Middle Georgia's uninsured turning to volunteer clinics, indigent care programs

Healthcare Coverage - Minnesota less generous with healthcare for childless, low-income adults

Healthcare Coverage - Number of those without insurance up 2 years running

Healthcare Coverage - Numbers of Americans with and without health insurance rose in 2002

Healthcare Demographics - Gender and geography increase racial disparities in health care

Healthcare Economics - California tax credit covers less than half average insurance premium

Healthcare Economics - New Hampshire employers issue groundbreaking proposal to state's insurers

Heart Disease Risk Factor - Favorable dietary fatty acid composition decreases heart disease risk

Heart Failure - Data show ultrafiltration is safe, effective and reduces hospital length of stay

Heart Failure - Five impedance cardiography studies presented

Heart Failure - Oxypurinol meets primary endpoints in recently completed trial

Heart Failure - Protein implicated in decline of aging hearts

Heart Pump - FDA approves AB5000 Ventricle

Heartburn - FDA approves prescription strength Pepcid AC for OTC

Helicobacter - Preliminary X-ray studies of ClpX from Helicobacter pylori reported

Hematological Cancer - NPM/MLF1 fusion linked to t(3;5) MDS and AML

Hematology - Gene studies show extramedullary tumor cell growth is highly regulated

Hematology - Nonanemic iron deficiency not associated with oxidative damage

Hematology - Pregnancy is not a contraindication for lipoprotein apheresis

Hemophilia - Acquired hemophilia A still has no standard for disease management

Hemophilia - Activated factor VII given to treat hemophilia can be checked by FVII:C assays

Hemophilia - New reconstitution kit launched

Hepatitis - Panel: Long-term efficacy of hepatitis A vaccination means no need for booster

Hepatitis A Virus - Excessive host response is a major cause of HAV-related liver failure

Hepatitis C Virus - Enrollment completed for new hepatitis C therapy clinical trial

Hepatitis C Virus - First head-to-head study of hepatitis C therapies in planning

Hepatocellular Carcinoma - PPAR delta plays an important role in the development of HCC

Hepatocellular Carcinoma - Telomere dysfunction differentially impacts initiation and progression of HCC

Herpes Simplex Virus - Recurrent HSV-1 blepharitis can occur for years without corneal involvement

Herpesvirus - Codon-optimization greatly improves U51 orf protein expression by HHV-6, HHV-7

Herpesvirus - HSV-1 pol exonuclease activity facilitates strand displacement

Herpesvirus - Herpes simplex virus 1 protein binds NFB42

High Cholesterol - Multicenter study to evaluate cholesterol ratios of patients treated with Lo-Chol

Hip Arthroplasty - Early loosening in Charnley total hip arthroplasty is linked to HLA A31₁₉

Hodgkin Disease - Mononucleosis doubles risk of lymphoma

Hodgkin Lymphoma - Antibody-cytokine fusion protein anti-CD30/IL-12 induces NK lysis of HL cells

Hospital Quality - Hospital care quality differs markedly by state, says annual study

Human Cytomegalovirus - HCMV's US2 induces degradation in epithelial, glial cells of both MHC-I, MHC-II

Human Genome - Analysis of gene knockouts yields more than 20 drug discovery programs

Human Immunodeficiency Virus - Virus entry is potential target for anti-HIV intervention

Human Serum Proteins - Tartrate-resistant acid phosphatase 5B is found in human serum in a complex

Humanized Yeast - $1M NIH grant to aid in the production of therapeutic proteins in yeast

Huntington Disease - Huntingtin induces tyrosine phosphorylation of N-methyl-D-aspartate receptors

Hypertension - Does body's synthesis of certain substances affect the relationship to obesity?

Hypertension - Does new hypothesis explain higher blood pressure among African Americans?

Hypogonadism - Testim testosterone gel improves bone mineral density in men

Hysterectomy - Sexual pleasure improves after procedure

Immune Evasion - Lyme disease Borrelia species bind factor H, thus cleave C3b complement

Immune Modifiers - Antimicrobial drugs may have immunomodulatory functions that could be used

Immune Tolerance - ADP-ribosylation factor-6 may be responsible for making human T cells anergic

Immunology - Coupled cytokine gene therapy increases tumor immunogenicity

Immunology - Genes selectively expressed by dendritic cells elicit specific immune response

Immunology - MBL may opsonize malaria-infected red blood cells

Immunology - Study: FK778 efficacious, well tolerated, safe in kidney transplant patients

Immunomodulators - Alpha-galactosylceramide may stop carcinogenesis by keeping NK, T cells active

Incontinence - FP1097 gets IND approval; company to open phase IIa trial