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Health & Medicine Week

Susan Hasty, Publisher
Table of Contents . . . October 27th, 2003
Non-Subscriber - Summaries Only
Related Areas: Other Issues in Health & Medicine Week | Other Publications

Pneumococcus - New vaccine for children reduces severe infection from common bacteria

Water-borne Illness - Home-treated water no better than plain tap in preventing GI illness

Complementary and Alternative Medicine - Diets largely based on plant foods are viewed more as improving health

Drug Marketing - Curious and confused: Prescription drug ads impact consumer health

Ethics - Minority children: Over- or under-represented in medical research?

Injury Prevention - Report: Home visits can reduce child abuse, gun control may not lessen violence

Shingles - Tai Chi class boosts shingles immunity

Vaccine Efficacy - Relation between vaccine efficacy and reproduction numbers explored

AIDS Epidemiology - A fifth of South Africa's military infected with HIV

AIDS Epidemiology - HIV/AIDS becoming a young person's disease, U.N. reports

AIDS Prevention - AIDS vaccines still elusive, but trials now include humans

AIDS Research - U.S.-Russian initiative to intensify cooperation in fight against disease

Accreditation - Arizona provider earns health plan accreditation from URAC

Acne - Positive Actiza phase III trial results reported

Acute Myeloid Leukemia - Mutations in FLT3 are the most common genetic lesions in AML

Addiction Medicine - Researchers receive $4.9 million grant to continue study of prenatal exposure

Adrenal Masses - Chemical shift MRI was found to be useful for identifying adenomas in most cases

Adrenal Tumors - Resection is the treatment of choice for adrenocortical tumors in childhood

Advanced Cancer - Oral tazarotene is well tolerated when administered daily for 12 weeks

Adverse Drug Effects - Apoptosis precedes necrosis in acetaminophen-induced liver injury

Airborne Pathogens - $8.4M NIH biodefense grants to be used for development of vaccines

Alcoholism - Correcting misperceptions can curb student drinking

Allergenic - DNA identification kit launched

Allergy - IMPAX receives approval for generic Claritin Reditabs

Allergy Medicine - Alpha-melanocyte-stimulating hormone kills mast cells; NF-kappa B can stop it

Allergy Medicine - Mast cell mediator increases bronchial macrophage-derived chemokine

Alzheimer Disease - Animal research points to new direction for AD therapy

Alzheimer Disease - Breakthrough cancer drug offers hope for Alzheimer patients

Alzheimer Disease - Consortium formed to advance state-of-the-art neurological research

Alzheimer Disease - Early, accurate diagnosis of AD possible with urine sample

Alzheimer Disease - Exercise and caregiver training can improve mood, physical health for patients

Alzheimer Disease - Insulin and IGF-1 may have therapeutic roles in Alzheimer disease

Alzheimer Disease - Physicist devises way to observe protein folding

Amyotrophic Lateral Sclerosis - Oxidative stress involved in neurodegeneration of ALS

Anal Fissures - Enrollment in Cellegesic phase III trial passes two-thirds mark

Angina - Demand grows for CO₂ laser angina therapy

Angiogenesis - Cancer center enrolling patients for colorectal cancer clinical trials

Angiology - Garlic attenuates time-dependent changes in reactivity of isolated aorta

Angiology - c-Jun N-terminal kinase inhibitor protects against cerebral ischemia

Anthrax - $3.5M grant from U.S. government used for drug to treat anthrax exposure

Anthrax - Taking aim at bioterrorism: Professor gets HHS funding

Anthrax - Year-long follow-up finds no further postal workers affected

Anthrax Vaccine - Biopharm company awarded $80.3M contract for anthrax vaccine candidate

Antibiotic Discovery - Mpex signs agreement with discovery chemistry company

Antibiotics - Licensing agreement reached for broad-spectrum antibiotic

Antibiotics - Ribosome binding thiazole antibiotics exhibit contrasting activities

Antibody Production - Immunoglobulin class switch recombination requires AID to affect dsDNA breaks

Anticancer Agents - Identification of best doses requires attention to dose limiting toxic events

Antifungals - Immunocompromised pediatric patients can be treated safely with caspofungin

Antigen Presentation - Recognition of antigens presented by HLA-A2 involves binding site recognition

Antigen-Presenting Cells - Even short rises to temperature increase hsp90, dendritic cell maturation

Antimicrobial Proteins - Human parotid secretory protein is an antibacterial in saliva and parotids

Antimicrobial Resistance - Multidrug transporters of E. coli play role in resistance to beta-lactams

Antimicrobial Resistance - Resistance to tiamulin caused by mutation of ribosomal protein L3

Antineuronal Antibodies - Anti-Ma2 antibody may occur in breast cancer expressing Ma1, Ma2, and Ma3

Antipneumococcal Activity - LPS binding protein also binds non-lipid sections of pneumococcal cell wall

Antisense Technology - Loop swapping changes the direction of helix progression in paired RNA

Antitumor Agents - Combretastatin A-4 analogues show potential as antimitotic antitumor agents

Apoptosis - Melatonin inhibits serum deprivation-induced apoptosis in rat hepatoma cells

Apoptosis Research - Cell-analysis company and University of Birmingham form research alliance

Array Technology - Single array launched for human genome expression analysis

Arterial Ischemic Stroke - Arterial ischemic stroke in neonates, infants, and children reviewed

Arteriovenous Fistulae - Treatment and outcome of spinal dural arteriovenous fistulas are examined

Arthritis - HLA region linked to heightened psoriatic arthritis risk

Asthma - Early-onset disease likely to recur

Asthma - Late asthma may be calmed by cyclosporin A; it eliminates Bcl-2 pos T cells

Asthma - Low-molecular-weight agents can cause non-IgE-associated occupational asthma

Asthma - Patients showed more improvement with ciclesonide compared with budesonide

Asthma Triggers - Asthma can be a risk in canary food handling; black seed may be responsible

Astrocytoma - PSC 833-inhibited cell growth and induced cell death in vitro in astrocytoma

Atherosclerosis - Endoplasmic reticulum is site of cholesterol-induced macrophage toxicity

Atrial Fibrillation - FDA grants premarket approval for ALERT Companion II

Autism - Autism rates drop in Denmark after removal of thimerosal from vaccines

Autoimmune Disease - Cathepsin V degrades thymic MHC-II peptides, increased in myasthenia gravis

Autoimmune Disease - Normally, autoantibodies produced by B cell precursors are eliminated at checkpoints

Autoimmune Disease - Protein microarrays guide DNA vaccine treatment of autoimmune disease

Awards - Agre Receives 2003 Nobel Prize in chemistry

Awards - American and Briton win Nobel for medicine

Awards - Cancer prevention pioneer receives award for ground-breaking research

Awards - MacKinnon wins 2003 Nobel Prize in chemistry

B-Cell Differentiation - Plasmacytoid dendritic cell cytokines induce plasma cell, antibody generation

Bacteremia - Completion of review of initial endocarditis/bacteremia data reported

Bacteriology - Bacterial class III adenylyl cyclases activated by bicarbonate ion

Bacteriology - Enzymatic DNA repair effective in bacteria with expanded genetic "alphabet"

Barrett Esophagus - There are questions remaining about reflux, Barrett esophagus, adenocarcinoma

Behavioral Health Care - More TennCare children get mental health services, but of lesser quality

Behcet Disease - Active Behcet disease has high IL-4, IL-10, IL-13; low IL-12, IFNgamma levels

Behcet Disease - Finding genetic, environmental factors in Behcet disease may help predict risk

Biliary Obstructions - Noncoronary stents introduced in U.S. and Europe

Bioengineering - Transfection points to the importance of crosslinking in engineered tissues

Biogenerics - Generic biologics to enter the U.S. market by 2008

Biogenic Amine Transporters - Lymphocytes transport neurotransmitters; transporter substrates alter immunity

Biological Agents - Biotech firm named finalist in U.S. Army competition for contract

Biological Weapons - Army study finds no illness link in biowarfare test subjects

Biopharmaceuticals - Biopharmaceutical company named as fast-growing company in Maryland region

Biosafety - University receives $18M for construction of biosafety facility

Biotechnology - A new technique offers oligonucleotide immobilization for hybridization

Biotechnology Research - New biotechnology research center for children's health to be built

Bipolar Disorder - College-age students do not associate untreated mental illness with risks

Blood Analysis - Medical device manufacturer closes blood analysis product line acquisition

Blood Coagulation - Protease-activated receptor-1 agonists mimic angiogenic activation

Blood Products - Prestorage leukocyte reduction advised for autologous donation

Blood Substitute - Oxygen binding of cross-linked bis-hemoglobins evaluated

Blood Testing - Serologic T. cruzi test suitable for field, blood bank use

Bone Fractures - Patients with vertebral compression fractures show improvement in pilot study

Brain Cancer - Novel therapeutic target identified for aggressive form of cancer

Brain Cancer - Study of brain tumors points to resection over biopsy as one key to survival

Brain Injury - Damage to the frontal lobes can affect a person's ability to "stay on the job"

Brain Injury - Traumatic brain injury treatment receives FDA fast track designation

Brain Tumors - Combination of 2D PAGE, MALDI-TOF-MS successful as global screening tool for CSF

Brain Tumors - New 3-D tortuosity metric seems to detect several kinds of abnormalities

Brain Tumors - New murine models enable scientists to decode brain tumor genetics

Breast Biopsy - A hybrid breast biopsy system combines ultrasound and MRI

Breast Cancer - Deaths on the decline, but survival gap differs by race

Breast Cancer - Food retailer and breast cancer foundation launch fundraising campaign

Breast Cancer - In vivo functions of the p160 steroid receptor coactivator family reviewed

Breast Cancer - Mammography use declines when breast cancer risk is greatest

Breast Cancer - New 10-year trial launched to study anastrozole

Breast Cancer - Over-the-counter pain relievers may block development of breast tumors

Breast Cancer - Research underlines importance of Modrenal as treatment option

Breast Cancer - Second part of rolling NDA submitted for RSR13

Breast Cancer - Simulation model used to predict doxorubicin activity in human breast cancer

Breast Cancer - Who and what are heard about the mammography screening controversy?

Breast Cancer Risk Factor - No link between exercise and breast cancer risk in premenopausal women

Breast Implants - FDA reconsiders silicone-gel implants

Brucellosis - Agglutination tests distinguish brucellosis from TB and other disorders

Bypass Surgery - Computer model shows that bypass surgery is more cost-effective than stents

Cancer - Sleep may fight cancer progression

Cancer Development - The p53 pathway is an attractive target in the war on cancer

Cancer Patient Care - Many patients do not understand terms used in cancer consultations

Cancer Pharmacotherapy - Pharmacotherapy of elderly cancer patients is based on younger patient trials

Cancer Risk - Re-analysis of data finds no evidence of dioxin cancer threshold

Cancer Susceptibility - Researchers map cancer susceptibility genes in the mouse

Cancer Therapy - Company publishes results of gene therapy approach for colon cancer

Cancer Therapy - Extract from the Magnolia plant targets tumor proliferation

Cancer Therapy - First human clinical trial with CO-501 initiated

Cancer Therapy - Panzem formulation selected enhances bioavailability

Cancer Therapy - Study indicates antitumor activity of Ceplene and chemotherapy

Cancer Therapy - The membrane-bound alkaline phosphatase gene enhances etoposide activity

Cancer Treatment - Ceramide metabolism may produce metabolites shown to signal antiapoptosis

Candidiasis - Farnesol's mode of action studied with 40 farnesol analogs

Cardiac Data - Cardiac monitoring company inks agreement with pharmaceutical company

Cardiology - DDAH modulates several elements of angiogenesis

Cardiology - Fusion between recipient- and donor-derived cells is a rare occurrence

Cardiology Care - Edward Heart Hospital plans expansion

Cardiomyopathy - Echocardiography shows sustained improvement in PG, septal walls

Cardiopulmonary Bypass - Clinical trial with Neuprex in pediatric open heart surgery patients to begin

Cardiovascular - Texan foreign-body retrieval device launched in Europe

Cardiovascular Diagnostics - Heart-health scanning device brought to China

Cardiovascular Disease - Patent issued for variations in inflammation gene that indicate increased CVD risk

Caregiving - Assistance program for families of critically ill patients expands across U.S.

Cell Signaling - Mathematical modeling predicts cellular communication

Central Nervous System - FDA puts phase III trial of antianxiety product on hold

Central Nervous System - Myelin-associated inhibitors of axonal regeneration reviewed

Cerebral Aneurysms - NIH grant to be used for development of a collagen-based coil

Cerebral Malaria - Role of TNF-alpha in cerebral malaria pathogenesis reviewed

Cervical Cancer - HLA-DRB1*1602 allele linked to HPV cervical infection in Bolivian Andean women

Cervical Cancer - Increased Cu, decreased Zn and Se may increase risk of cervical cancer

Charcot-Marie-Tooth Disease - Inflammatory demyelination reported in a patient with CMT1A

Chemotherapy - Heterogeneity has an effect on optimal regimens in cancer chemotherapy

Chemotherapy - TNFR2 participates in cisplatin-induced renal injury

Childhood Immunization - New vaccines may address need to protect newborns in the developing world

Childhood Tumors - Clinical, cellular pharmacology in relation to childhood solid tumors reviewed

Chondrogenesis - Gene expression changes evaluated in an in vitro model of chondroinduction

Chronic Alcohol Use - Pancreatitis following chronic alcohol use may be caused by hypoxia

Chronic Kidney Disease - New guidelines on bone disease in CKD address deficiencies

Chronic Obstructive Pulmonary Disease - COPD patients improve with roflumilast

Chronic Venous Ulcers - Company reports results of clinical trial of repifermin

Clinical Genomics - HP collaborates on individualized medicine initiative

Cognitive Function - Biological basis for creativity linked to mental illness

Collaborations - Agreement signed for cardiac safety monitoring services

Collaborations - Agreement signed to develop antibodies for cancer treatment

Collaborations - Chemistry-based oncology alliance extended

Collaborations - Global influenza partnership signed with Sankyo

Collaborations - Library license agreement signed for discovery of therapeutic antibodies

Colon Cancer - Genetics supersedes epigenetics in colon cancer phenotype

Colon Cancer - Metastatic lesions from colorectal carcinomas don't show more somatic mutations

Colon Cancer - Novel gene therapy approach suppresses tumors in preclinical tests

Colorectal Cancer - Advanced colorectal cancer therapy to undergo phase I/II trial

Colorectal Cancer - Biologics license application filed for Avastin

Colorectal Cancer - Data submitted to FDA for clearance to market test to monitor colon cancer

Colorectal Cancer - InSure test significantly increases patient participation in screening

Colorectal Cancer - Novel derivatives of indomethacin may have an improved safety profile

Comparative Genomics - Mice have fewer CD1 proteins than humans due to a genomic deletion

Complementary and Alternative Medicine - Ayurvedic medicinal Withania somnifera appears to relieve chronic stress

Complementary and Alternative Medicine - Green tea catechins go through specific molecules to inactivate VEGF

Complementary and Alternative Medicine - Many different compounds isolated from Plantago are immunostimulatory

Complementary and Alternative Medicine - St. John's wort affects neuroendocrine responses to 5-T-2A agonist

Complementary and Alternative Medicine - Study shows tea consumption lowers blood cholesterol

Compliance - People are averse to taking drugs

Computed Tomography - Multidetector row helical CT provides valuable anatomical information

Congenital Disease - Bartter syndrome and immune complex nephropathy may be linked

Congestive Heart Failure - FDA approves Inspra for improving survival of patients after a heart attack

Congestive Heart Failure - Initial results of the TRISVR Multi-Center Registry reported

Consumer Products - Lubrizol completes personal-care ingredients acquisition

Consumer-Directed Healthcare - Company will offer new coverage option to employees

Consumer-Directed Healthcare - Health management company offers in-depth CDHC training resource

Consumer-Directed Healthcare - HealthTrust selects program to offer its public employer groups

Consumer-Directed Healthcare - Providers urged to focus on small to midsize market

Contraception - In Uganda, male community-based distributors enhance family planning

Contraception - New progestins offer multiple benefits to women's health

Contracts - E-communications security firm announces contracts with two hospitals

Cord Blood - Biotech company receives cord blood to enhance stem-cell expansion technology

Coronary Artery Bypass - Same-day discharge appears safe in majority of transfemoral coronary stentings

Corporate Update - Biotech company progress reported following mergers

Corporate Update - Device firm adds metered dose inhaler manufacturing capabilities

Corporate Update - Global sales, marketing organization launched for biologics testing

Corporate Update - HealthSouth divides ambulatory services into two separate divisions

Corporate Update - Nanotechnology company consolidates marketing efforts

Corporate Update - SLICES maker reports on operations

Coxsackievirus - Arginine-glycine-aspartic acids play role in pathogenesis of coxsackievirus

Coxsackievirus - Structure of swine vesicular disease virus reported

Critical Limb Ischemia - FDA panel recommends non-approval of laser angioplasty

Crystallography - Crystallography of TCR, MHC peptide complex don't support dual recognition model

Cytokine Expression - Monoallelic expression of IL-1 alpha occurs in normal, arthritic human T cells

DNA Research - Gaps in East Asian mitochondrial DNA phylogeny filled

DNA Research - Statistical technique improves PCR nucleic acid analysis

DNA Research - The detection of DNA damage by key proteins leads to nucleotide excision repair

DNA Vaccine - Vaccine encoding superoxide dismutase protects against brucellosis

Deep Vein Thrombosis - ActiveCare DVT System now available

Degenerative Brain Diseases - Squid research unlocking mysteries of the brain

Dendritic-Cell Activation - CD1 and MHC-II molecules are in mature DC, despite lysosome reorganization

Dendritic-Cell Formation - TNF controls monocyte differentiation; dendritic cells form versus macrophages

Dendritic-Cell Function - Dendritic cell apoptosis or expansion may be controllable by synthetic retinoids

Dengue Fever - Dengue fever outbreak occurs in Palau, Western Pacific

Dental Implants - Titanium surface topography affects behavior of osteoblast-like SaOS-2 cells

Depression - As antidepressant treatment increases suicide rates decrease among adolescents

Depression - Brain activity linked to treatment-resistant depression

Depression - Brain imaging helps to understand depression

Depression - FDA issues second approvable letter for Cymbalta

Depression - Regulatory plan reiterated after pre-PMA-S meeting with FDA

Depression - Researchers finds gene variations that alter antidepressant side effects

Dermatology - FDA approves generic lidocaine/prilocaine cream

Dermatology - MBI 594AN phase IIb acne trial complete

Dermatology - Partnership to raise awareness of dry skin conditions

Developmental Biology - Signaling molecule crucial in formation of heart valves

Developmental Biology - Study describes how genes orchestrate facial expressions

Diabetes - HLA haplotype influences diabetes risk in atomic bomb survivors

Diabetes - Heightened CBV antibodies seen in HLA DR3-, MICA5.1-positive Linkoping diabetics

Diabetes Epidemiology - Researchers find children stricken by both type 1 and type 2 disease

Diabetes Mellitus - Company completes phase IIa study of CS-917

Diabetes Pathogenesis - Fatty acids plus elevated glucose cause pancreatic beta-cell death

Diabetes Pathogenesis - Pancreatic-derived factor induces apoptosis of insulin-secreting beta-cells

Diabetes Pathogenesis - Transgenic mice expressing B7-1 in beta cells susceptible to diabetes

Diabetes Survival and Mortality - CT findings of unusual complications related to diabetes reported

Diabetes Survival and Mortality - Vascular NAD(P)H oxidase is target of therapy for diabetic complications

Diabetes Therapy - Inhibition of forkhead transcription factor improves fasting glycemia in mice

Diabetes Therapy - Novel thiazolidinedione antihyperglycemic agents synthesized

Diabetic Neuropathy - Peroxisome proliferator-activated receptors promote diabetic inflammation

Diagnostics - In situ-labeled cell surface proteins identified by mass spectrometry

Diagnostics - Inverness Medical acquires certain rapid-diagnostics assets

Diagnostics - Potentiometric method used to measure saccharin in sweeteners

Diagnostics - Preprocessing of tandem MS data supports automatic protein identification

Diet and Nutrition - Antiaging effects of caloric restriction involve macroautophagy stimulation

Diet and Nutrition - Creatine supplementation causes liver inflammation in mice but not rats

Disease Management - Compliance system developed for newly required cancer protocol checklists

Disease Management - Employers embrace approach to control costs, improve quality

Disease Surveillance - Study evaluates effectiveness of ED computers in identifying outbreaks

Disease Susceptibility - Recombinant mannan-binding lectin will soon be available to improve serum levels

Dog Genome - Illinois study seeking biomarkers of canine diabetes, other diseases

Domestic Violence - New federal grant program will help religious groups fight violence in the home

Down Syndrome - Fetal diagnostic test combo shows promise

Down Syndrome - Hypothalamic digoxin-mediated model for trisomy 21 proposed

Drosphila Genome - Companies set to distribute RNAi set

Drug Development - S. cerevisiae gene expression profiling clarifies drugs' antifungal activity

Drug Development - Novel cephalosporin shows promise

Drug Development - PET scanning is expanding the horizons of oncology drug development

Drug Development - Sulfanylbenzoic acid derivatives of salicylanilides have enhanced antimycobacterial activity

Drug Development - Two NIH biodefense grants to be used for vaccine development

Drug Discovery - Medarex enters collaboration to develop fully human antibody therapeutics

Drug Prices - Canada drug company opens doors to governors, mayors

Drug Resistance - Gene therapy and chemotherapy combine to stop breast cancer and its metastasis

Drug Resistance - Resistance patterns of pneumococcal diseases in adults with HIV reported

Echinococcus Multilocularis - Three immunoreactive antigens from Echinococcus multilocularis are found

Electronic Prescriptions - Massachusetts Senate approves e-prescribing

Emotion - Pathways of emotion - from cortex to peripheral organs - described

Emotion - Rejection really hurts, psychologists find

Emphysema - Results from preclinical study of Ilomastat presented

Employment Benefits - California workers get health insurance help

End-of-Life Issues - Couples therapy may be a useful adjunct to end-of-life care

Endocrinology - Estradiol does not appear to influence postpartum uterine involution

Endocrinology - Prenatal nicotine exposure sets the stage for future behavior

Endocrinology - The aldosterone antagonist spironolactone diminishes angiogenesis

Endometrial Infection - Complement regulatory proteins may protect endometrium from complement lysis

Endothelium - Flk-1 and Flt-1 receptors take a time-dependent course in rat brain expression

Enrollment - Preferred provider organization enrollment on the rise

Environmental Health - Global urbanization exerts significant impacts on health

Environmental Health - High burdens of 2,2',4,4'-tetrabromodiphenyl ether found in California women

Environmental Health - Impedance method detects bacteria and fungi in bottled purified water

Environmental Health - Metabolites of polychlorinated biphenyls reported in human tissues

Environmental Health - Polybrominated and polychlorinated compounds found in human breast milk

Enzymology - Matrix metalloproteinase inhibitors look viable for treating several ailments

Enzymology - Specific alpha v integrin receptors modulate murine melanoma activity

Epilepsy - Company receives tentative approval for generic Topiramate tablets

Epilepsy - Magnetic fields guide brain surgery

Epstein-Barr Virus - EBV-linked nasopharyngeal carcinoma does not have altered cytokeratins

Erectile Dysfunction - Could a specific protein contribute to impotence for diabetic, obese men?

Escherichia coli - E. coli O157:H7 and Shigella sonnei express green fluorescent protein

Esophageal Atresia - Researchers obtain clues to role of the Shh gene in esophageal atresia

Esophageal Cancer - German esophageal cancers are linked to Epstein Barr virus, not papillomavirus

Esophageal Cancer - Researchers review optimal therapy for esophageal cancer

Estrogen Receptor Modulators - SERM royalty agreement amended; Royalty Pharma exercises a $12.5M option

Exercise - Strength training is safe for healthy children and adolescents

FAcilities - HMA receives approval to build a 100-bed hospital in Collier County, Florida

Facilities - Hospital Partners of America acquires Houston facility from Tenet

Facilities - Ohio contract research organization opens Munich office

Fascioliasis - Fatty acids bound to Fasciola hepatica differ from those in adult flukes

Fertility - Male contraceptive trial results in no pregnancies

Fertility - Sperm from marijuana smokers move too fast, too early

Fetal Medicine - Toxemia, specific language impairment may be caused by low essential fatty acids

Finance - $4M to $7M budgets help business development teams win alliances

Finance - $9.2 Million financing to be used for launch of bone repair products

Finance - Alfalfa-extracts company reports a $24M investment deal, new president and CEO

Finance - Anti-infectives drug firm raises UKP 25M

Finance - Biotech company's chairman adopts Rule 10b5-1 trading plan

Finance - Cancer-focused biotech files $125-million shelf-registration statement

Finance - Cancer-screening company's shares relisted on OTC bulletin board

Finance - Cardiovascular drug maker reports decreased revenues

Finance - Cholesterol-monitoring company reports on FY03, predicts continued growth

Finance - Colorado device company announces financing commitment

Finance - Contract-research organization reports 47% increase in revenues in first quarter

Finance - Dental pharmaceuticals company to sell 2M shares of common stock

Finance - Device firm improves cash position by 16%

Finance - Diagnostic product manufacturer sells 5,000,000 shares of common stock

Finance - Diagnostics company announces $2M private placement

Finance - Diagnostics company announces exchange offer

Finance - Drug-discovery company raises $42.7 million in series B funding

Finance - Exercise of over-allotment option valued at approximately US$33M

Finance - Hearing diagnostics, infant screening sales benefit from marketing initiative

Finance - Home-care products company issues $100 million in senior notes

Finance - Hormone therapy company commences trading on AMEX

Finance - IMPATH files Chapter 11

Finance - Imaging company reports continued revenue increase

Finance - Imaging company updates fourth quarter guidance

Finance - Magellan reorganization plan gains support of largest unsecured creditor

Finance - Marr Technologies increases investment in maker of HIV-screening test

Finance - Medifast posts record revenues; YTD up 125% to $19.5M

Finance - Microarray company to trade on Amex

Finance - NDCHealth revenue increases, income drops in first quarter

Finance - Pharmaceutical firm announces $41M direct equity placement

Finance - Pharmaceutical firm announces revised exchange offer

Finance - Pharmaceutical firm's resale registration statement declared effective

Finance - Public offering reported by diabetes drug maker

Finance - Reagent company earns $3.7 million in net income in first quarter

Finance - Respiratory care products company reports earnings

Finance - SEC declares oncology company's resale registration statement effective

Finance - Supplements company reports increased operating income for the year

Finance - Vaccine company withdraws previously announced financing

Finance - Vision company obtains first tranche of interim financing

Finance - Wellbutrin maker provides guidance on third quarter 2003 results

Finance - Zicam developer increases guidance for FY2003

Finances - Biotechnology company raises $11.5M in private placement

Fitness - Exercise for elders: It's never too late

Fitness - Strength training may help elderly rebuild muscles, improve health

Flexible Spending Accounts - FSAs help consumers cover health, child care

Food Allergy - Peanut allergy characteristics and management reviewed

Food Safety - Lactate dehydrogenase immunoassay marks when beef cooking eliminates bacteria

Food-borne Disease - Steam pasteurization not sufficient for hygienic beef processing

Food-borne Illness - Bioassay and LC-MS methods compared for measuring enrofloxacin in whole eggs

Food-borne Illness - Tufts wins $25 million NIH contract

Forensic Medicine - DNA extraction techniques facilitate assault investigations

Fragile X Syndrome - Neurodegeneration caused by the fragile X premutation rCGG repeats

Fraud - Half of hospital's fine will fund health care for poor

Funding - Drug discovery company receives $300K in grants

Fungal Infections - Tinea infections may require topical antifungals or systemic therapy

Gastric Carcinoma - MBD4 mutations are rare in gastric carcinomas with microsatellite instability

Gastroesophageal Reflux - There is weak support for association between GER, both sinusitis, laryngeal Ca

Gastrointestinal Surgery - Low levels of mannan-binding lectin give higher risk of postsurgical infection

Gene Chips - Human genes made to fit on a chip the size of a dime

Gene Expression - What can digital transcript profiling reveal about human cancers?

Gene Polymorphisms - Toxicogenetics pinpoints genetic polymorphisms responsible for adverse reactions

Gene Regulation - Propranolol induces gene expression in children treated for burn injuries

Gene Suppression - Antisense to urokinase-type plasminogen and its receptor stifles cancer

Gene Targeting - Lentiviral vectors have advantages for brain cell transfection

Gene Transfer - A new gene delivery method may ameliorate cancer recurrence after resection

Gene Transfer - The particle gun method ensures offspring transgene inheritance in fish

Generalized Anxiety Disorder - Lexapro gets approvable letter from FDA

Generic Drugs - Pharmaceutical company receives tentative approval to manufacture new generics

Generics - Drug makers hope to profit from WTO decision on medications

Genetic Disorders - Bayesian spatial statistics improve analysis of haplotype effects

Genetic Disorders - FISH analysis can identify marker chromosomes

Genetic Disorders - Familial cluster of dendriform pulmonary ossification reported

Genetic Disorders - Gene locus for novel form of Joubert syndrome identified

Genetic Disorders - Hereditary sensory neuropathy locus found on chromosome 3p22-p24

Genetic Disorders - Loci with possible effects on age of Huntington disease onset identified

Genetic Disorders - Novel ARS (component B) mutation linked to Mal de Meleda

Genetic Disorders - Novel spastin mutations and their expression reported in two Italian families

Genetic Mutation - Diagnostics company launches cystic fibrosis test

Genomics - Antisense molecules with specific thermodynamic values have high hit rates

Genomics - Invitrogen enters agreement to optimize gene-expression analysis

Genomics - The human genome still will play a large role in the future of medicine

Genomics and Genetics - Role of Prickle and Strabismus in planar cell polarity clarified

Genomics and Genetics - Role of histone H2A.Z in gene transcription elucidated

Geriatrics - Gender and apolipoprotein E are predictive factors for Alzheimer disease

Germ-Cell Tumors - High-dose carboplatin dosing strategy studied in patients with germ cell cancer

Glioma - ERBB receptor tyrosine kinases, cellular radiation responses reviewed

Gorlin Syndrome - Spectrum of PTCH1 mutations reviewed in French patients with Gorlin syndrome

Government Initiative - NIH announces strategy to accelerate medical research progress

Graft-versus-Host Disease - CD4+CD25+ T cells are potent regulatory cells

Group Purchasing - HealthSouth selects MedAssets HSCA as supply-chain partner

Gynecological Cancer - Group therapy improved mood disturbance and sexual dysfunction after cancer

Gynecology - Alternative cell entry allows oncolytic agents to target ovarian cancer

Gynecology - Cure for salpingitis often necessitates combination therapy

Gynecology - Gonadotropin-dependent ovarian follicle development depends on VEGF stimulation

Gynecology - Intermittent therapy can treat women with premenstrual dysphoric disorder

Gynecology - Outcomes after the repair of vesico-vaginal fistulas are usually good

Gynecology - Ovarian expression of the bradykinin B-2 receptor is usually static

Gynecology - Strict criteria define a finding of bacterial vaginosis upon Pap smear staining

HIV Prevention - $10M in milestone funding to be used for HIV fusion inhibitor

HIV Prevention - $16.7M NIH contract to develop HIV vaccine

HIV Therapy - Antiretroviral therapy reduces HIV-1 transmission when started after childbirth

HIV Therapy - Preclinical testing of second generation HIV viral entry inhibitor expanded

HIV Vaccine - Biopharmaceutical company awarded $19M contract to develop HIV vaccine

HIV Vaccine - Pharmaceutical company awarded contract to develop HIV vaccine

HIV Vaccine - Phase II study of Remune with HIV-infected patients begins in Italy

HIV-1 Antibodies - Approval sought for HIV-1 test that detects antibodies in oral fluid or plasma

HIV/AIDS Coinfection - HCV and HIV coat proteins collaboratively mediate hepatocyte IL-8 release

HIV/AIDS Gene Therapy - Modified promoter improves anti-HIV siRNA efficacy

HIV/AIDS Lipodystrophy - Predictors of HIV dyslipidemia identified

HIV/AIDS Neurotoxicity - Schwann cell chemokine receptors mediate HIV gp120 toxicity to sensory neurons

HIV/AIDS Pathogenesis - CD28-dependent HIV-1 transcription is associated with Vav, Rac, and NF-kappa B activation

HIV/AIDS Pathogenesis - Coinfection with X4 strain augments HIV infectivity

HIV/AIDS Pathogenesis - MBL inhibits DC-SIGN-mediated HIV "trans" infection of T cells

HIV/AIDS Pathogenesis - Virus-associated C-PKA regulates HIV infectivity

HIV/AIDS Theapy - CCR5-disrupting molecules can prevent HIV infection

HIV/AIDS Therapy - IL-15 levels may predict STI outcome in chronic HIV patients

HIV/AIDS Therapy - Neural networks can help identifiy HIV lopinavir resistance mutations

HIV/AIDS Therapy - Quadruple antiretroviral regimens compared

HIV/AIDS Therapy - Rapamycin downregulates CCR5 and heightens anti-HIV chemokine levels

HIV/AIDS Therapy - Ritonavir-boosted saquinavir and indinavir have similar efficacy

HIV/AIDS Therapy - Testosterone supplements can improve HIV patients' quality of life

HIV/AIDS Tuberculosis - FNAC useful for diagnosis in HIV patients with lymphadenopathy

HIV/AIDS Vaccine - Adenoviral vector HIV vaccine stimulates enhanced mucosal IgA response

HIV/AIDS Vaccine - Cytotoxic-T-lymphocyte responses elicited by multiepitope DNA vaccination

HIV/AIDS Vaccine - SHIV 89.6 proviral DNA and live virus elicit similar immune responses

HIV/AIDS Vaccine - SIV virus-like particles conjugated to cholera toxin elicit immune responses

Hantavirus Vaccine - DNA vaccine protects against hantavirus pulmonary syndrome

Haplotype Variability - Unequal crossing over of tandem KIR genes may promote haplotype variation

Head and Neck Cancer - Adenovirus-mediated p16 gene therapy combats radiation-resistant cancer cells

Headache and Migraine - ATP1A2 mutations linked to familial migraine with aura

Health Insurance - Consumers find opportunities to save on healthcare costs

Health Insurance - Insurance denied Swiss HIV patients despite reduced death rate

Health Management - I-trax and Horizon Blue Cross Blue Shield of New Jersey sign deal

Health Reimbursement Accounts - American Medical Security offers HRA program for small employers

Healthcare Access - Blue Cross of California to accept Mexican ID cardholders

Healthcare Access - Hawaii re-establishes its Office of Health Equity

Healthcare Access - Plan to distribute AIDS drugs presented to health minister

Healthcare Benefits - Blue Care Network of Michigan will cover Prilosec, Claritin

Healthcare Benefits - Groups clash over employer healthcare mandate

Healthcare Benefits - Survey reports over half of California employers support healthcare mandate

Healthcare Benefits - Survey reveals health insurance buying trends

Healthcare Costs - Disease management saves $36 million in 1 year

Healthcare Coverage - Cancer patients without insurance have lower survival rates

Healthcare Coverage - Census Bureau and Institute of Medicine reports spur call to action

Healthcare Coverage - Grants enable low-income uninsured in Arizona to gain access to medical care

Healthcare Coverage - Healthcare for Washington, DC, poor is way over budget

Healthcare Coverage - New clinic in Maine offers free health care

Healthcare Coverage - Pennsylvania sees big jump in residents without health insurance

Healthcare Coverage - States receive federal grants to study uninsured populations

Healthcare Coverage - Use of emergency departments for treatment of minor ailments increasing

Healthcare Economics - Governor's order will keep Kentucky workers' premiums equal statewide

Healthcare Economics - Market conditions can allow providers to shift costs to offset government cuts

Healthcare Economics - Open enrollment means maximizing benefits, minimizing costs

Healthcare Economics - Oregon governor backs off new state drug rule

Healthcare Economics - Other states look to Oregon's example to control drug costs

Healthcare Economics - Partnership aims to promote innovative solutions to keep health care affordable

Healthcare Economics - Report: Missouri's healthcare costs rising above national average

Healthcare Economics - State could lose locally owned pharmacies under new plan

Healthcare Economics - Study assesses the hidden costs of administering intravenous antibiotics

Healthcare Insurance - 2003 shows an increase of 13.9% in private health insurance

Healthcare Premiums - Hawaii health insurer seeking rate increase

Healthcare Reform - Consumer involvement urged in policy decision-making

Healthcare Reform - Workers worry about job health coverage; express interest for government plan

Hearing Disorders - Genes that regulate hearing link humans and fruit flies in new way

Heart Disease Initiatives - Commission launches new research projects to combat cardiovascular disease

Heart Disease Mortality - Women surpass men in heart disease deaths, U.N. health agency reports

Heart Failure - Blood volume analyzer purchased by New York medical center

Heart Failure - FDA approves humanitarian use device status for AbioCor implantable heart

Heart Transplant Risk - A regimen without prednisolone in heart transplant may lower bone disease

Hematology - Bone marrow angiogenesis is implicated in hairy cell leukemia progression

Hematology - Brain morphogenetic gene Otx1 plays unexpected role in hematopoiesis

Hematology - Glycosylation restores survival of chilled blood platelets

Hematology - Oxidized low-density lipoprotein stops VEGF-induced cell differentiation

Hematology - Platelet proteinase-activated receptors play a significant role in tumor growth

Hematology - Pro- and anticoagulant proteins decreased during childhood

Hematology - Quantum dot-based probes aid erythrocyte study

Hematology - The cdx4 gene specifies hematopoietic cell fate

Heme Oxygenase - Heme catabolism by heme oxygenase-1 yields 3 potential protective therapeutics

Hemodialysis - Service company receives clearance to market sorbent hemodialysis cartridges

Hepatitis B Vaccine - Seroepidemiology of hepatitis B virus in Addis Ababa reported

Hepatitis C Therapy - Ribavirin has an inhibitory effect on HCV polymerase-mediated RNA synthesis

Hepatocellular Carcinoma - COX-2 promotes hepatocellular carcinoma cell growth through AKT activation

Hepatocellular Carcinoma - Ultrasound findings, histopathology correlation evaluated in HCC

Hepatology - Upregulated transactivating factor may play a role in liver metabolism

Herbal Medicine - Elevated gamma glutamyl in kava consumers doesn't reflect liver injury

Hookworm - Human hookworm maintained through 100 generations in golden hamsters

Hormone Replacement Therapy - Trial results have dramatically reduced HRT use

Hospitalization - Isolated patients may get less care

Hydrosurgury - SpineJet Curette handpiece gets FDA clearance

Hypercholesterolemia - Insurer declines to cover cost of new cholesterol drug

Hypertension - European approval of Remodulin delayed

Hypertension - Weight control throughout life key to reducing risk of raised blood pressure in middle age

Hypoxia - Agreement signed for access to eTag assay system

Imaging - Hospital for Special Surgery opens imaging center

Immune Deficiency - Initiative addresses primary immune diseases

Immune Epiduritis - Pediatric acute immune epiduritis is treatable with polyvalent immunoglobins

Immunization - Rural Britons consider drinking unpasteurized milk healthy

Immunology - Antibody responses to Wolbachia surface protein characterized

Immunology - HIV protein attacks body's innate protection system that could prevent virus' replication

Immunology - Interleukin-4 targets angiogenesis by arresting cell growth cycles

Immunology - Morphine suppresses p53-mediated lymphocyte apoptosis

Immunology - Paper highlights preclinical results of HIV peptide vaccine

Immunology - Self-antibodies in hepatitis C patients suggest immune response cross reactions

Immunology - The TNF2 allele is an independent risk factor for severe aplastic anemia

Immunology - The many human type I cytokines and their receptors are similar and coevolved

Immunosuppression - Radiotherapy patients given zinc supplementation have fewer oral infections

Immunosuppression Risk - Crystallography reveals structure of acyclovir-bound HsPNP

Industry Trends - After rough period, biotech industry on upswing in New Jersey, Pennsylvania

Infection - StaphVAX confirmatory-phase-III trial ahead of schedule

Infectious Disease - CDC partners with University of Liverpool for research alliance

Infectious Disease - Epidemic cholera strains reemerging in Bangladesh

Infectious Disease - Hantavirus epidemiology in Argentina characterized

Infectious Disease - Persistent infection impairs the immune system

Infectious Disease - Scottish foot and mouth epidemic reduces human cryptosporidiosis rate

Infectious Disease - Texas joins CDC's Emerging Infections Program network

Infectious Disease - Tim-3 molecule involved in fine balance of immune response

Infectious Disease - VZV meningitis can mimic lymphoma in HIV patients

Infectious Disease Therapy - Co-trimoxazole may be effective against MRSA

Infertility - FDA panel issues favorable recommendation for Luveris in follicular development

Inflammation - Insulin-like growth factor gene transfer assuages the effects of burn injury

Inflammation Suppression - New anti-TNF-alpha therapy will involve small molecule, oral inhibitors

Inflammatory Bowel Disease - Phase I clinical study of APAZA compound complete

Inflammatory Diseases - Crohn disease etiology has not been found; there are many treatment options

Inflammatory Myopathy - S100 proteins MRP8, MRP14 are secreted by macrophages, cause myocyte apoptosis

Influenza - CDC outlines racial/ethnic disparities in elderly vaccine recipients

Influenza - Immune response to flu shot different in people with mild symptoms of depression

Information Technology - Cleveland Clinic to deploy medication management solution

Information Technology - Electronic scheduling service wins contract with British health system

Information Technology - HIMSS and MS-HUG announce unification

Information Technology - Lawson launches healthcare grant-management application

Information Technology - MDS signs global-technology outsourcing agreement

Information Technology - New release expands administrative system software for health plans

Information Technology - Software helps reduce medication errors

Injury Prevention - Child restraint seats in airplanes could cause more deaths than they prevent

Injury Prevention - Guns may hold "unique allure" for young boys

Injury Prevention - Paper analyzes concussions in professional football

Innate Immunity Lectin - Transfusion of recombinant mannan-binding lectin may help treat many diseases

Insulin Resistance - Unrestricted metabolic research grant awarded to Beth Israel Deaconess

Interleukin - IL-6 gene expression increases in human adipose tissue after exercise

International Health - No link between hepatitis C and non-Hodgkin lymphoma can be found in Turkey

Irritable Bowel Syndrome - Company to discontinue U.S. development of dexloxiglumide

Ischemic Stroke - Herpes simplex virus-based gene delivery generates neuroprotective effects

Kaposi Sarcoma - Human herpesvirus-8 superinfection reported

Kidney Disease - A new decoy oligodeoxynucleotide blocks mesangial cell proliferation

Kidney Disease - Six professionals awarded $50K each in support of kidney disease research

Kidney Tumors - Renal epithelioid angiomyolipoma can metastasize, may be a malignant type tumor

Legal Issues - Doctors file lawsuit over slow returns on insurance claims

Legal Issues - Judge signs TennCare settlement involving home care

Legal Issues - State challenges ban on 'any willing provider' law

Legal Issues - Supreme Court debates states' ability to get out of healthcare settlements

Leiomyosarcoma - 13q14-q21 loss, 5p14-pter gain could identify patients with shorter survival

Leukemia - Gene profiling may lead to customized treatments for pediatric patients

Leukemia - New studies examine racial differences and outcomes for children

Lipid Studies - Lipoprotein distribution in type 2 diabetes described

Lithium Test - FDA clearance granted to market InstaRead rapid test for psychiatric use

Liver Cancer - Response after carbogen-based functional MRI yields tumor vasculature data

Liver Cirrhosis - Suppression subtractive hybridization characterizes the genetics of cirrhosis

Liver Damage - Research collaboration to identify biomarkers of choline deficiency

Liver Failure - Bioartificial liver support systems bridge the transplantation gap

Liver Failure - The premise of adoptive immunity via transplantation needs more exploration

Long-Term Care - Groups present ways to reform state's system

Longevity - Long, healthy life may be associated with larger size of lipoproteins in blood

Lung Cancer - Chemoradiotherapy treatment of unresectable, locally advanced NSCLC evaluated

Lung Cancer - FDA special protocol assessment review for Telcyta completed

Lung Cancer - Molecular mechanisms assist Rb2 gene in blocking cells

Lung Cancer - Myth could stop patients from getting care, researchers say

Lung Cancer - Non-small cell lung cancer treatment does not meet primary efficacy endpoint

Lung Cancer - Time course of postoperative CEA level changes can predict patient prognosis

Lyme Disease - Galactoside is immunogenic motif in Borrelia burgdorferi sensu stricto

Lymphoma - p21 Promoter methylation is involved in some low-grade MALT lymphomagenesis

MHC Genetics - Polymorphic regions, indels are clustered together in MHC frozen block area

Macrophage Activity - Increases in TNF-alpha by lovastatin can be blocked by inhibition of ERK

Macrophage Redox Functions - 17 Beta-estradiol affects Ca²⁺ transport in macrophages and thus ROS, NO

Magnetic Resonance Imaging - The formation of a cerebral mycotic aneurysm was captured by serial imaging

Malaria - Bilirubin levels rise during malaria-associated renal impairment

Malaria - Novel P. falciparum antioxidant protein identified

Malaria Epidemiology - P. falciparum in Colombia is genetically homogeneous

Malaria Epidemiology - Illegal Chinese immigrants bring malaria to Italy

Malaria Immunology - Javanese migrants to Indonesian Papua develop malaria immunity

Malaria Pathogenesis - Erythrocyte G protein-coupled receptor signaling involved in malaria infection

Malaria Therapy - Malarial hemozoin formation elucidated

Malaria Therapy - Paroxysm serum from P. vivax infection blocks P. falciparum maturation

Malaria Vaccine - Vaccine based on Pichia pastoris shows promise against malaria

Malignant Melanoma - Genistein enhances the cisplatin-induced inhibition of cell growth and apoptosis

Market Analysis - Drug market for multiple sclerosis will be driven by growth of patient population

Medi-Cal - Legislation signed to fight fraud by providers

Medicaid - Advocates for the poor say dental and eyeglass care not expendable

Medicaid - Federal judge rules in healthcare dispute

Medicaid - HMS to provide healthcare revenue-recovery services in Maryland

Medicaid - Health budget cut could knock thousands off public health program rolls

Medical Malpractice - Group forms medical liability company

Medical Malpractice Insurance - Australian government, doctors fail to avert health crisis in insurance

Medical Malpractice Insurance - California's largest insurer to slash rate hike after increase is challenged

Medical Malpractice Insurance - Physician responses to rising premiums may reduce access, increase costs

Medicare - Ad campaign encourages Congress to enact comprehensive reform in 2003

Medicare - Federal judge upholds limits on therapies covered by program

Medicare - Groups say proposed bills contain multibillion dollar cuts for cancer drugs

Medicare - Lawmakers to defray e-prescription costs

Medicare - Report: Private sector can provide seniors a high-quality managed drug benefit

Medicare - Study finds privately insured in N.H. pay for program's shortfalls

Medication Safety - Enhanced tamper-evident packaging features introduced

Mediterranean Spotted Fever - Mediterranean spotted fever risk in humans may increase with infected dogs

Melanoma - Adhesion-dependent activation of the ERK1/2 cascade is bypassed in melanoma

Melanoma - Grading of atypia in nevi has a correlation with melanoma risk

Melanoma - Immunological data from phase II cancer trials of vaccine published

Melanoma - Melanocyte transformation to melanoma involves activation of certain oncogenes

Meningitis - Even in WNV epizootic areas, enteroviruses still main cause of meningitis

Menopause - Genes for estrogen and vitamin D receptors associate with bone mineral density

Menopause - Subjective sleep quality improves in those who take combination hormone therapy

Menorrhagia - Desmopressin may not increase local fibrinolytic activity during menstruation

Mergers and Acquisitions - American Capital invests $49M in buyout of radiation dosimetry services

Mergers and Acquisitions - American Hospital Resources intends to acquire pharmacy provider

Mergers and Acquisitions - Centene to acquire Medicaid-related assets of Family Health Plan

Mergers and Acquisitions - Fisher's SPS is acquired by Medmark

Mergers and Acquisitions - Gene Logic announces postacquisition integration and market-alignment strategy

Mergers and Acquisitions - Gene silencing company acquired for gene, protein studies

Mergers and Acquisitions - Genesis Bioventures, Inc., provides merger update

Mergers and Acquisitions - Hycor files registration statement on Form S-4

Mergers and Acquisitions - IGEN announces early termination of the waiting period under Hart-Scott-Rodino

Mergers and Acquisitions - IsoTis merger almost complete

Mergers and Acquisitions - Kendle completes acquisition of Mexican contract-research organization

Mergers and Acquisitions - Letter of intent signed to acquire Plan B

Mergers and Acquisitions - LifePoint Hospitals and Norton Healthcare finalize Spring View transaction

Mergers and Acquisitions - Net Force gains controlling interest in vaccine company in Mainland China

Mergers and Acquisitions - Nutra Pharma Corp. to acquire diagnostic-kit company

Mergers and Acquisitions - Pharmaceutical company acquires vessel closure technology firm

Metastatic Bone Disease - Bisphosphonates, radiation therapy can be used for metastatic bone disease

Microarray Technology - Company to launch first whole human microarray by end of year

Migraine - FDA approves new Zomig (zolmitriptan) nasal spray formulation

Migraine Headache - Sumatriptan succinate tablets effective in treating menstrual migraines

Military Defense - Company may get $3M more from Defense Department for health-monitoring vest

Molecular Imaging - Research collaboration optimizes molecular imaging techniques for oncology

Mosquito-borne Disease - More A. gambiae genes expressed after blood meal identified

Mosquito-borne Disease - Veterinary vaccine candidate ChimeriVax-West Nile virus grown in mosquitoes

Multiorgan Disease - IVIG and clarithromycin resolve pediatric macrophage activation syndrome

Multiple Myeloma - Agreement reached on STR phase III registration trial

Multiple Myeloma - DNA microarrays may have scientific, clinical applications in multiple myeloma

Multiple Myeloma - IL-6-induced proliferation of myeloma cells is associated with CD45 molecules

Multiple Myeloma - Pathogenetic mechanism of anemia based on persistent erythroblast cytotoxicity

Multiple Myeloma - Proteasome inhibitors suppress IRE1alpha, lower XBP-1, leading to apoptosis

Multiple Myeloma - Therapeutic implications of apoptotic signaling in multiple myeloma reported

Multiple Sclerosis - Detection of antibodies could identify patients who do not respond well to interferon beta

Multiple Sclerosis - Licensing rights to Fampridine-SR expanded

Multiple Sclerosis - MS has four subtypes, histologically; demyelination may be from different causes

Multiple Sclerosis - Reduction of MS lesions by interferon-beta may involve MMPs, adhesion molecules

Multiple Sclerosis - Research: Copaxone slows accumulation of disability and reduces relapse rate

Myelodysplastic Syndrome - Bone marrow B lymphocytes undergo apoptosis in myelodysplastic syndrome

Myeloma Therapy - Treosulfan shows promise for multiple myeloma treatment

Myocardial Infarction - Genetic markers linked to heart attacks

Nanobacterial Infections - Study will evaluate nanobacterial endotoxin in patients undergoing angioplasty

Narcolepsy - Sodium oxybate has gone from club drug to orphan drug to treat cataplexy

Nasu-Hakola Disease - Osteoclasts depend on TREM-2 to fully differentiate; lack of TREM-2 produces NHD

Natural-Killer Subtype - NK in the maternal decidua have chemokine receptors influenced by local cells

Nausea - Schering-Plough inks licensing agreement for palonosetron

Needlestick Injury - Healthcare product supplier awarded contract for drug delivery system

Neonatology - Company launches family of neonatal oxygen-delivery hoods

Nephrectomy - Laparoscopic radical nephrectomy has outcomes equivalent to open nephrectomy

Nephrogenic Diabetes - Sugar coupled to protein causes kidneys to save water

Neurologic Disease Genetics - Multiple sclerosis, even after whole genome screens, has had few genetic hits

Neurology - 14-3-3 Proteins in the nervous system reviewed

Neurology - BACH function elucidated

Neurology - Disease mechanisms in inherited neuropathies reviewed

Neurology - Distal motor and residual latency are markers of anti-MAG polyneuropathy

Neurology - Osmotic swelling induces p75 neurotrophin receptor expression

Neurology - Structure of JNK3 in complex with small molecule inhibitors reported

Neuropathic Pain - Positive results reported in phase II trial with cannabinoid compound

Neuroprotective Drugs - Parkinson disease drug pramipexole functions by speeding dopamine uptake

Neuroscience - MARS alleviates neurological progression in liver disease-related coma

Neuroscience - MRI of the spinal-cord helps to confirm multiple sclerosis diagnoses

Neuroscience - Parturition activates proteins that initiate maternal behavior

Neuroscience - Role of dopamine D4 receptor gene mutations in ADHD clarified

Neuroscience - Zic2 plays key role in binocular vision

Neurotoxin - Toxic phospholipase from venom of Vipera ammodytes meridionalis reported

Nicotine Addiction - At current rate of decline, smoking prevalence will not meet 2010 goal

Nicotine Addiction - New study shows genes may influence smoking cessation

Non-Hodgkin Lymphoma - Company initiates NDA submission for Onco TCS

Non-Hodgkin Lymphoma - Innovative strategies challenge conventional thinking about lymphoma therapy

Non-Hodgkin Lymphoma - Phase II/III clinical development program initiated for anti-cancer agent

Nutrition - Study: Increased multivitamin use by the elderly could save Medicare $1.6B

Nutrition - Vitamin D deficiency emerges as new epidemic

Nutrition Education - Changes to dietary guidelines will be futile without improved education

Obesity Epidemiology - Obesity associated with occupation in Madagascar

Obesity Epidemiology - Prevalence of severe obesity increasing faster than obesity in the U.S.

Obesity Pathogenesis - Salt increases oxidative stress in rat model of diet-induced obesity

Obesity Risk Factor - Stress promotes weight gain in certain rats on medium-fat diet

Obesity Surgery - Surgical obesity treatment reduces risk of musculoskeletal pain

Obesity Survival and Mortality - Obese patients have lower survival rates while undergoing hemodialysis

Obesity Therapy - Atkins' medical practice closes

Obstetrics - Alloimmune thrombocytopenia can be detected and even treated in utero

Obstetrics - Conservative management for uterine rupture is ill advised

Obstetrics - One-third of women feel distant from partner post-miscarriage

Obstetrics - Pregnant asthmatic women can limit newborn complications using beta2 agonists

Obstetrics - Pregnant women at risk for thrombosis should be given prophylactic heparin

Obstetrics - Premature birth has lifelong effects

Obstetrics - Targeted food supplementation helps pregnant women meet nutrition goals

Obstetrics - UCLA study finds healthier babies born to immigrant mothers

Oncology - Cryopreservation allows women to preserve fertility despite chemotherapy

Oncology - Extra chromosome 12 material associates with tumor aggression

Oncology - Genes on 17q may be involved in the pathogenesis of classical Hodgkin lymphoma

Oncology - Suppression of the oncoprotein c-Myc sends melanoma into a tailspin

Oncology - Tight regulation of transferred plasmids leads to cancer inhibition

Oncoproteins - Interactions of p21 ras oncoproteins with cellular receptors modeled

Ophthalmology - CNTF gene transfer rescues photoreceptors from antibody-induced death

Opthalmology - Genes are a major factor in the onset of age-related macular degeneration

Oral Carcinogenesis - High risk HPVs 16 and 18 increase in prevalence as oral cancer progresses

Oral Carcinoma - Topical inhibition of oral cancer cell occurs with polymer-delivered celecoxib

Oral Lesions - Human papillomavirus types produce different oral tumors and lesions

Oral Lesions - Oral mucous membrane pemphigoid should be recognized early by dentists

Orthopedics - Exercises may help to prevent knee injuries

Orthopedics - Feedback loops regulate bone morphogenic protein, SMAD genes, and chondrocytes

Orthopedics - Grant will further research on healing bone injuries

Osteoporosis - Hormone therapy reported effective in fracture prevention

Osteoporosis - Long-term pamidronate reduces bone resorption by limiting osteoclast function.

Osteoporosis - Menatetrenone ameliorates loss of bone mineral density in immobilized rats

Osteoporosis - Observational analysis: Risedronate reduced nonvertebral fracture risk

Osteoporosis - Oral salmon calcitonin phase IIa data presented

Osteoporosis - Study results prompt ACOG statement on HRT for bone loss prevention, treatment

Otorhinolaryngology - PLUNC proteins may be antibacterials that protect mouth, nose, lung epithelium

Outbreaks - Candida rugosa may be emerging human pathogen

Outbreaks - Automated, laboratory-based system to detect disease outbreak developed

Outbreaks - Laboratory electronic reporting inadequate for bioterrorist attack

Ovarian Cancer - Statistical model may preoperatively distinguish benign from malignant tumors

Over-the-Counter Medication - Group counsels patients on self-treatment

PET Technology - New three-dimensional examination technology introduced

Pain Medicine - Glial cell-derived neurotrophic factor genes relieve neurotrophic pain

Pain Medicine - Natural chemical curbs neuropathic pain

Pain Therapy - Progress report provided on the development of ENT-103

Pancreatic Cancer - Company announces global expansion of Virulizin phase III trial

Pancreatic Cancer - Further characterization may lead to better understanding of cellular pathways

Pancreatic Cancer - Microarrays may advance understanding of pathobiology of pancreatic cancer

Pancreatitis - Clinical uses for duodenoscope-assisted cholangiopancreatoscopy reviewed

Parasitology - Malaria parasite takes advantage of liver

Parkinson Disease - Animal models offer insight into role of alpha-synuclein in Parkinson disease

Patents - Biotechnology corporation granted patent for gene delivery technology

Patents - New U.S. patent issued for vascular targeting agents

Patents - Oxidant scavengers patent may affect amyotrophic lateral sclerosis

Patents - Through-hole array intellectual property portfolio purchased

Patents - U.S. patent granted for bifunctional compounds

Patents - Xencor Granted Patent on Optimized Pharmaceutical Protein

Pathogen Recognition - Pattern-recognition receptors may initiate inflammation in lung infection

Patient Recruitment - Participation in clinical trials improves women's health

Patient-Centered Healthcare - Marketing expert thinks approach is more effective, efficient

Pediatric Chemotherapy - Pediatric leukemia patients have a risk of herpes simplex virus ulcerations

Pediatric Mental Health - Relief of poverty associated with improvement in some psychiatric disorders

Pediatric Obesity - Don't rely on BMI to indicate weight problem in children

Pediatrics - Environmental factors during late pregnancy influence infant growth components

Pediatrics - Multidisciplinary approaches benefit children with neuromuscular disorders

Pediatrics - Surgical drainage is key to resolving bacterial cervical lymphadenitis

Personnel - Ari E. Bizimis resigns; Charles Galetto to assume CFO duties

Personnel - British drug-discovery company assembles chemistry team

Personnel - Cardiovascular company names Beverly H. Lorell, MD, to new VP position

Personnel - Clinical trials management company appoints new chief executive officer

Personnel - Contract-research organization announces executive appointments

Personnel - Drug-discovery company appoints David C. Hastings as chief financial officer

Personnel - Frances Nolan joins life-science consultancy

Personnel - George Paz to become president of Express Scripts

Personnel - Haruhiko Hirate becomes president of Banyu Pharmaceutical

Personnel - Joe Lahti, Gary Griffin join cell-therapy company's technology board

Personnel - Karen A. Dawes named to board of directors of gene-variation company

Personnel - Leung named VP, quality and manufacturing at genetic diagnostics company

Personnel - Lipid company names Rosemary L. Walzem, PhD, as visiting scientist

Personnel - Medical device company appoints new president and chief executive officer

Personnel - Mitchell Kronenberg, PhD, named president of allergy institute

Personnel - Molecular regeneration company names Matthew Gantz president and CEO

Personnel - Noonan named to board of directors at devic firm

Personnel - Paterson joins pharmaceutical firm

Personnel - Positron emission tomography equipment supplier names new president and CEO

Personnel - Reinhard Koenig, MD, named to biotech management team

Personnel - Senate confirms ex-Lilly executive as White House AIDS coordinator

Personnel - Spence Young named as director of reimbursement and national accounts

Personnel - Starr named to board of directors at RNA company

Personnel - VP of business development named at pharmaceutical firm

Personnel - Vancouver Biotech expands management team

Personnel - Vice chairman, president named at biotech company

Personnel - Warthen named VP of sales, business development at lab IT company

Pharmacology - Controllers of adrenergic receptor subtypes heighten placental blood flow

Physician Practice - Doctor's communication style may sway cancer patients

Poliovirus - Poliovirus VPg uridylylation not required for negative-sense genome synthesis

Postoperative Pain - FDA accepted DepoMorphine NDA for filing

Preeclampsia - Increased debris from apoptotic syncytiotrophoblasts may induce preeclampsia

Preeclampsia - Th1 profile in preeclampsia is related to inflammation and poor placentation

Pregnancy - High CRP in first trimester increases preeclampsia, growth restriction risk

Pregnancy Complications - Early membrane rupture in twin pregnancy may be caused by neonatal infection

Prenatal Care - AME churches spread family planning message in South Carolina

Prenatal Testing - Company announces milestone in development of noninvasive Down syndrome test

Prescription Drug Importation - Rx Depot case one of savings vs. safety

Preventive Medicine - Study says managed care insurers should offer more prevention programs

Preventive Medicine - To prevent heart disease, many would rather change lifestyle than take drugs

Prion Diseases - RNA may boost rogue prions

Prison Healthcare - Moore Medical signs multiyear distribution agreement

Prostate Cancer - Distribution of prostate carcinoma foci in the peripheral zone is homogeneous

Prostate Cancer - Epirubicin alone should not be used to treat hormone-resistant prostate cancer

Prostate Cancer - Integrated biologic-based therapy may be key in management of prostate cancer

Prostate Cancer - Long-chain polyamines exhibit strong cytotoxicities against prostate cancer

Prostate Cancer - Major study indicates complexed PSA test more accurate than traditional PSA test

Prostate Cancer - Phase III registrational trial of satraplatin in begins

Prostate Cancer - Pin1 enzyme shown to predict severity of prostate cancer

Prostate Cancer - Preclinical data on Mdm2 antisense oligonucleotide published

Prostate Cancer - Relation between body mass index and risk of prostate cancer is complex

Prostate Cancer - Research may aid cancer diagnosis

Prostatectomy - Evolution of endoscopic extraperitoneal radical prostatectomy (EERPE) reviewed

Protein Regulation - Promyelocytic leukemia protein is a positive p53 regulator; Mdm2 is negative

Protein Regulation - The influence of angiotensin II on angiogenesis is vessel dependent

Proteomics - Luteococcus japonicus protein reactivates cells inactivated by UV

Proteomics - Albumin characterized with matrix-assisted laser desorption ionization TOF-MS

Proteomics - Echistatin and RGD peptide reduce orthodontic tooth movement

Proteomics - Extracellular matrix patterns diverge in neonatal and adult liver fibrosis

Proteomics - Functional analysis of C-TAK1 substrate binding reported

Proteomics - GDF-5 deficiency stymies angiogenesis, proliferation, and other cell activities

Proteomics - Integrin-mediated Ras-ERK signals use two pathways to stimulate angiogenesis

Proteomics - Nafamostat mesilate is extremely potent inhibitor of human tryptase

Proteomics - Non-covalent protein complexes analyzed by electrophoresis-MS

Proteomics - Novel mechanism of protein phosphatase specificity and activity proposed

Proteomics - Spondyloepiphyseal dysplasia tarda protein studied

Pseudomonas - Monomeric pilin adhesion molecule for P. aeruginosa crystallizes as a dimer

Pseudomonas - Researchers find promising new avenues for treating infections

Pseudorabies Virus - Pseudorabies infection not affected by spermine, spermidine, or DFMO

Psoriasis - Fumaderm - oral psoriasis therapy - licensed from Fumapharm

Psoriasis - New light unit assembly expands phototherapy applications

Psychology - Behavioral contracting motivates athletes with eating disorders

Psychosis - Spending on psychotropic drugs for youths increased in the late 1990s

Public Health - Survey: Public misjudges greatest threat to the nation's health

Pulmonary Arterial Hypertension - Remodulin study data show reductions in mean pulmonary arterial pressure

Pulmonary Tumor Embolism - Microscopic pulmonary tumor embolism is rarely recognized before death

Pulse Oximetry - Advocate Health Care converts to Masimo SET oximetry

Purchasing - Trade group says innovation, competition stifled by group purchasing schemes

Quality Assurance - Kaiser Permanente earns top ratings in 2003 national quality watchdog report

RNA Research - BC1 RNA stimulates exploration in mice

RNA Research - HIC protein modulates P-TEFb-dependent HIV transcription

RNA Research - Histone H5 integration has little effect on nucleosome

RNA Research - Intellectual property, expertise reported in hepatitis research

RNA Research - PSF regulates HIV expression via viral mRNA instability elements

RNA Research - RLM-RACE sequencing modified for use with double-stranded viral RNA

RNA Research - RNA polymerase II CTD needed for pre-snRNA 3' end formation

RNA Research - RNA primer activation signal needed for efficient HIV reverse transcription

RNA Targets - Scientists seek to find out function of microRNAs

Rabies - Skunk and raccoon rabies in the eastern United States followed

Rabies Virus - Variants of rabies viruses found with distinct epidemiological origins

Radiosensitivity - Identifying common signal may uncover targets for developing protocols

Reactive Oxygen Species - Reactive oxygen species play role in regulation of intrinsic prion protein

Recall - Nationwide recall issued for device used to determine blood-clotting time

Regulatory Issues - FDA stops sale of supplements making misleading claims about obesity, impotence

Regulatory Issues - Missouri HMO pays fine for payment violation

Regulatory T-Cell Deficiency - Foxp3 is the gene critical for development of regulatory T cells

Reimbursement - CMS awards $5M contract to SRA

Reimbursement - Maxim to use codingANYware, Lanvision's remote coding workflow solution

Reimbursement - Medicare expands coverage of left ventricular-assist devices

Reimbursement - Permanent code assigned for reimbursement of capsule endoscopy

Relocation - Biotech contract-research organization moves headquarters to Colorado

Renal Cancer - Renal imaging important in diagnosis and staging of renal cell carcinoma

Renal Cancer - [¹⁸F]FDG PET efficiently detects distant metastases from renal cancer

Renal Cell Carcinoma - Chemotherapeutic strategies need to be discovered for renal cell carcinoma

Renal Cell Carcinoma - Monoclonal antibodies may be key in treatment for renal cell carcinoma

Renal Cell Carcinoma - Partial nephrectomy reduces risk of chronic renal insufficiency

Renal Cell Carcinoma - Researchers compare MR imaging of renal cell carcinoma to pathologic findings

Renal Cell Carcinoma - Researchers discuss prognostic factors in renal cell carcinoma

Renal Cell Carcinoma - Researchers review current staging of renal cell carcinoma

Renal Cell Carcinoma - The genetic basis of renal cell carcinoma reviewed

Renal Cell Carcinoma - Three-dimensional spiral CT can assist in planning nephron-sparing surgery

Renal Cell Carcinoma - ZD1839 treatment did not result in complete, partial responses in renal cancer

Renal Transplantation - Nonmitogenic CD3 antibody can be used to treat acute kidney allograft rejection

Reproductive Medicine - Aging brain adversely affects fertility of female rats

Reproductive Medicine - Socioeconomics associate with vaginosis risk in pregnant women in Bangladesh

Respiratory Syncytial Virus - Company files Numax investigational new drug application

Respiratory Syncytial Virus - Milestone achieved with filing of IND application for Numax

Retinal Ischemia - Pentoxifylline may have protective effect in retinal ischemia/reperfusion injury

Retinitis Pigmentosa - The genetics of blindness disease uncovered

Rheumatoid Arthritis - Beneficial effects of antibodies to interferon-gamma presented

Rheumatoid Arthritis - Bonding in rheumatoid arthritis model reported

Rheumatoid Arthritis - Company launches shortage product for early-stage rheumatoid arthritis

Rheumatoid Arthritis - IgG fusion protein BAFF-R-Fc may be better at antagonizing BAFF than BCMA-Fc

Rheumatology - Gene transfer in SCID mice provides a new way to assess disease models

Rotator Cuff Repair - Rotator cuff tendon has vascularity present 2.5 mm from the tear margin

SARS - CDC: SARS fear may swamp emergency rooms

SARS - Contract awarded from NIH for development of SARS vaccine

SARS - Singapore developing disease-detecting microchip

SARS - Study shows disease in kids tends to be mild

Salmonella - Enhancement of procedure to detect Salmonella in foods reported

Sarcomas - Mechanisms of sarcoma development reviewed

Schizophrenia - Density-95-associated protein-1 gene not linked to schizophrenia

Seborrheic Dermatitis - Malassezia yeasts may be responsible for seborrheic dermatitis; antifungals work

Secondhand Smoke - New clinical studies show accuracy of TobacAlert

Sexually Transmitted Disease - Chlamydia trachomatis regulates genes that reinforce its viability

Sjogren Syndrome - Kikuchi-Fujimoto disease can develop secondary to prolonged Sjogren syndrome

Sleep - U.S. patents filed to reformulate sleep drugs into lingual sprays

Smallpox - Epidemiologic, clinical, and preventive aspects of smallpox outlined

Smallpox - First big success seen in smallpox treatment research project

Smallpox - Grant will be used to develop vaccine against smallpox

Smallpox - Researchers examine models for outbreak severity prediction

Smoking Cessation - Effect of smoking reduction on later cessation evaluated

Spasticity - FDA grants approval for tizanidine hydrochloride

Spinal Cord Injury - Macrophage therapy improves function of damaged spinal cords in study

Spinal Cord Injury - Thoughts translate to actions

Spinal Surgery - New implant designed to treat spinal degeneration and support spinal mobility

Sports Injuries - Survey shows that almost 1/3 of runners did not seek medical help for injuries

Squamous Cell Carcinoma - A genetically based tumor classification system will soon be possible

Staphylococcal Infection - High clonal diversity seen in Norwegian MRSA isolates

Stem-Cell Research - A58 oncogene can immortalize hematopoietic cells

Stem-Cell Research - Embryonic stem cells produced via nuclear transfer of human somatic nuclei into rabbit oocytes

Stem-Cell Research - HOXB4 increases cell regeneration after in vivo stem-cell selection

Stem-Cell Research - Hematopoietic and mature blood cells can differentiate into cardiomyocytes

Stem-Cell Research - MyoR inhibits embryonic cell differentiation

Stem-Cell Research - Overexpressed hepatocyte growth factor treats the heart following ischemia

Stem-Cell Research - Positional identity gene expression codes not preserved in cultured neural stem cells

Stem-Cell Research - SDNSF helps maintain lifelong neurogenesis

Stem-Cell Research - Use eggs, not embryos, to derive stem cells, say researchers

Stem-Cell Research - WiCell earns national designation

Stem-Cell Transplantation - Costimulation blockade induces hematopoietic chimerism, central tolerance in SCT patients

Stem-Cell Transplantation - HLA class I and II typing may improve SCT outcome

Stem-Cell Transplantation - Rituximab active against refractory chronic GVHD

Stem-Cell Transplantation - SCT schedule affects post-transplant T-cell repertoire

Stock Market - Purification company receives NASDAQ notice of noncompliance

Stress - Chronic stress increases glucocorticoids, catecholamines

Stress - Life in a fearful global climate affects the health of many Americans

Stroke - Researchers uncover the brain's stroke protection system

Stroke - Vision restoration therapy to be launched in U.S. and Europe

Stroke Rehabilitation - Imagining movement of affected limbs aids stroke recovery

Sudden Infant Death - Deadly decision: Where should baby sleep?

Surgical Instruments - Arthroscopic shaver handpiece provides new level of performance

Systemic Lupus Erythematosus - Human endogenous retroviral peptides could be responsible for SLE

Systemic Lupus Erythematosus - Lower TCR zeta-chain in SLE is due to alteration, reducing the halflife

T-Cell Adhesion - Attachment of T cells to collagen is altered by lovastatin, phospholipase C

T-Cell Attachment - CD28 and small Rho GTPase Cdc42 are involved in actin rearrangement by T cells

T-Cell Differentiation - Repressor of GATA may be involved in differential development of Th2, Tc2 cells

T-Cell Function - K+ channels involved in immune functions may be future therapeutic targets

T-Cell Function - The cytotoxic T-cell surface, even when resting, contains over 100 antigens

T-Cell Receptor - TCR activation doesn't need multimerization; heterodimerization model may work

Technology - PC computing grid extends research and development capabilities

Telemedicine - Devices enable healthcare providers to remotely interact with patients

Telemedicine - Grant will put tiny Vermont home-health agency in technology forefront

Tendon Function - Dancer's tendinitis study shows areas with low vascularization can rupture

Therapeutic Proteins - NRC Biotechnology Research Institute enters strategic alliance

Thromboembolic Disease - Protein C pathway in infants and children reviewed

Thrombosis - Antiphospholipid syndrome has specific risks depending on beta2GPI antibody type

Thymocyte Development - BAF chromatin remodeling occurs at all stages of thymocyte development

Tobacco Use - Cigarette smoke exposure induces large increases in oxidative stress markers

Tonsillar Mononuclear Cells - Immature cytokine type 1 responses occur in RSV bronchiolitis, atopy cases

Total Hip Arthroplasty - Polyethylene wear acetabular cup monitoring by digitized radiography evaluated

Toxicology - Acetaminophen restriction curbs new emergency liver transplants in the U.K.

Toxoplasmosis - Dendritic cells provide protection against Toxoplasma gondii

Transdifferentiation - Stem cell versatility questioned

Transfusion Medicine - Dipyridamole improves efficacy of plasma exchange in TTP patients

Transfusion Medicine - Internet-based global apheresis registry initiated

Transfusion Medicine - MDS Nordion licenses x-ray blood irradiation technology

Transgenics - Effective promoters identified for high-level transgene expression in tobacco

Transplant Medicine - Docetaxel may have role in treatment of cancer arising in transplant recipients

Transplant Medicine - Spleen transplantation may induce tolerance, but GVHD can occur too

Transplantation - HMO approves kidney transplant for HIV patient

Transplantation - Interferon therapy prior to liver transplant curbs hepatitis C recurrence

Tuberculosis - Growing HIV-1 epidemic reducing multidrug-resistant TB control in Latvia

Tuberculosis Epidemiology - Low genetic diversity seen in Turkish TB isolates

Tuberculosis Latent Infection - NO-induced respiration inhibition triggers tuberculosis latency

Tuberculosis Pathogenesis - MBL gene mutations linked to TB resistance

Tuberculosis Pathogenesis - Mycobacterial transcriptome used to characterize infected phagosome biochemistry

Tuberculosis Pathogenesis - Role of CR3 in macrophage-mycobacteria interactions clarified

Tuberous Sclerosis - TSC2 regulates VEGF through mTOR-dependent and -independent pathways

Tumor-Cell Invasion - MT1-MMP may be a collagenase essential for tumor cell invasive growth

Type 2 Diabetes - Altered kidney regulation of COX-2 occurs at very early stage in nephropathy

Type 2 Diabetes Therapy - Drug therapy of diabetes in the elderly outlined

Typhus - First cases of north Asian tick typhus among North Americans reported

Ulcerative Colitis - Immunosuppressant sales for treatment of ulcerative colitis to double by 2012

Ureteral Defect - Reconfigured colon segments can be used as a ureteral substitute

Uterine Fibroids - Uterine fibroid embolization may be safer than abdominal myomectomy

Vaccine Development - Smallpox Research Grid delivers research results to U.S. Defense Department

Vaccines - Defense appropriations bill dedicates $3M to anthrax/plague vaccine

Varicella-Zoster Virus - Herpes zoster takes larger toll than varicella in Australia

Vascular Therapy - Enrollment completed in phase III trial of E2F Decoy

Vector Development - Ablation of CAR- and alpha(V) integrin-binding doesn't abort Ad5 tropism

Vertebral Tumors - Vertebroplasty is safe, beneficial, and improves functional status

Viral Infection - Enveloped viruses may enter host using lipid raft cholesterol, sphingolipids

Virology - Recombinant vesicular stomatitis virus is effective against metastatic cancer

Virology - The 5' untranslated region of GB virus C highlights genotypic differences

Weight Management - Kaiser, HealthMedia to study effectiveness of tailored online weight management

West Nile Virus - Most patients with West Nile virus encephalitis responded rapidly to ARB

West Nile Virus - Purdue team solves structure of virus

West Nile Virus - Season saw screening weaknesses, a rash of polio-like cases

Women's Health - Components of comprehensive evaluation of the older female patient discussed

Women's Health - Estrogen induces CRABP(II) gene expression in rat uterus

Women's Health - Oregon hospital honored for excellence tailoring care specifically for women

Wound Healing - Platelet-derived growth factor has influence on wound healing microcirculation

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