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Health & Medicine Week

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Alzheimer Disease



Insulin and IGF-1 may have therapeutic roles in Alzheimer disease



October 27th, 2003

Insulin and insulin-like-growth-factor 1 (IGF-1) may have therapeutic roles in the treatment of Alzheimer disease.

According to a study from Italy, "Aging is characterized by a significant decline of metabolic and hormonal functions, which often facilitates the onset of severe age-associated pathologies."

"One outstanding example of this is the reported association of deranged signaling by insulin and insulin-like-growth-factor 1 (IGF-1) with Alzheimer's disease (AD)," said Laura Gasparini and Huaxi Xu at the Nicox Research Institute in Milan. "Recent compelling biological data reveal effects of insulin and IGF-1 on molecular and cellular mechanisms...


Source: Health & Medicine Week (2003-10-27)

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