Melanoma
Melanocyte transformation to melanoma involves activation of certain oncogenes
Published in Health and Medicine Week, October 27th, 2003
"Solar ultraviolet radiation (UV) is a major environmental factor that dramatically alters the homeostasis of the skin as an organ by affecting the survival, proliferation, and differentiation of various cutaneous cell types," investigators in the United States report.
"The effects of UV on the skin include direct damage to DNA, apoptosis, growth arrest, and stimulation of melanogenesis. Long-term effects of UV include photoaging and photocarcinogenesis. Epidermal melanocytes synthesize two main types of melanin:...
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