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Multiple Sclerosis

Detection of antibodies could identify patients who do not respond well to interferon beta

Published in Health and Medicine Week, October 27th, 2003

Danish research highlights how the detection of antibodies to interferon beta - the first-choice treatment for multiple sclerosis patients - could be important in identifying patients who do not respond well to interferon beta, with implications for the provision of alternative drug therapy.

Interferon beta is the first-line treatment for relapsing-remitting multiple sclerosis, but the drug can induce neutralizing antibodies against itself, which might reduce its effectiveness.

Per Soelberg Sorensen from Copenhagen University Hospital, Denmark, and colleagues measured neutralizing antibodies every year for up to 5 years among 541 patients with...

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