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Vaccine Efficacy
Relation between vaccine efficacy and reproduction numbers explored
October 27th, 2003
A scientist has proposed expressions involving relations among transmission, vaccine coverage and reproduction numbers. According to recent research published in the journal Mathematical Biosciences, "We consider the impact of a vaccination program on the transmission potential of the infection in large populations. We define a measure of vaccine efficacy against transmission that combines the possibly random effect of the vaccine on individual susceptibility and infectiousness. This definition extends some previous work in this area to arbitrarily heterogeneous populations with one level of mixing, but leads us to question the usefulness of the concept of...
Source: Health & Medicine Week (2003-10-27)
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