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Health and Medicine Week

Susan Hasty, Publisher

Table of Contents . . . December 1st, 2003

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Health and Medicine Week | Other Publications

Smallpox - Immune memory from vaccination lasts more than 50 years

Stress - "Type A" parents may be creating hostility in children

Alcoholism - College kids underestimate alcohol consumption

CAD Risk - Survey shows significant gap between patient education and action

Heart Failure - Condition in elderly patients uses significant healthcare resources

Memory - Nicotine, or a similar substance, may improve memory

Mesothelioma - Blood marker for diagnosis shows early promise

Metastasis - Tumor growth follows same curve as animal growth

Occupational Health - Repetitive work tasks linked to bone damage

ADHD - Company works to amend its non-approvable New Drug Application

AIDS Epidemiology - Bisexuality, abuse, drugs behind AIDS spread among South's rural blacks

AIDS Prevention - China can use lessons from anti-SARS battle to take on AIDS, U.N. expert says

Acquired Hemophilia - Acquired factor VIII inhibitor-related can occur with myelodysplastic disorder

Acute Care - V.A.C. maker reports net revenue of $198.0 million for the third quarter

Acute Myeloid Leukemia - Farnesyltransferase inhibitors in AML and myelodysplastic syndromes

Acute Myocardial Infarction - Drug proved to benefit heart attack victims vastly underused

Acute Myocardial Infarction - Newer formulation of heparin improves outcomes for suspected MI patients

Acute Myocardial Infarction - Women and men differ in heart disease traits and treatment

Addiction Medicine - High-dose methadone linked to QT prolongation and Torsades de Pointes in HIV patients

Addiction Medicine - Methadone users need access to orthotopic liver transplantations

Addiction Medicine - Patients with alcoholic etiologies fare worse in a study of steatohepatitis

Adverse Drug Effect - Growth hormone therapy may kill; monocytes produce IL-1alpha, IL-6, TNFalpha

Adverse Drug Effects - Eprex induces reversible antierythropoietin antibodies and red cell aplasia

Agriculture Threat - Domestic animals may be bioterrorism targets; broad health, economic damage possible.

Airway Inflammation - Induced sputum can be used in PCR to assay for cytokines in airway inflammation

Alexander Disease - Alexander disease with glial fibrillary acidic protein mutation reported

Allergy Epidemiology - Study reveals dramatic rise in allergic diseases

Allergy Medicine - FDA approval granted for loratadine

Alzheimer Disease - Alzhemed open-label phase II extension study demonstrates cognitive benefits

Alzheimer Disease - Beta-AP1-40 and beta-AP40-1 possess different selectivities to oxidation

Alzheimer Disease - Data reported on monthly injectable sustained-release formulation of ZT-1

Alzheimer Disease - E2-25K/Hip-2 plays essential role in mediating amyloid-beta neurotoxicity

Alzheimer Disease - Herpes research uncovers possible clue to AD

Alzheimer Disease - Imaging damaged brain cells in living mice provides clues to dementia

Alzheimer Disease - Neprilysin inhibition raises amyloid beta levels in rabbit cortex

Alzheimer Disease - New vaccine tested in animals may hold hope for patients

Alzheimer Disease - Pravastatin does not decrease amyloid-beta in humans

Alzheimer Disease - Researchers find role RNA plays in progress of AD

Alzheimer Disease - Three disease compounds acquired from Sankyo

Anesthesia - Patients' concerns reviewed

Angina - Diabetics have worsening symptoms prior to acute cardiac event

Angiology - Protein S deficiency presents as deep vein thrombosis

Angioplasty - CREST study finds cilostazol reduces restenosis by almost 40%

Angioplasty - Michigan project cuts problems and deaths

Anorexia Nervosa - Role of adipocytokines in anorexia nervosa reviewed

Anthrax - Anthrax-laden USPS facility successfully fumigated

Anti-Oxidants - Adenosine receptors regulate oxidative stress in rat pheochromocytoma cells

Antifungal Therapy - Improved diagnosis of fungal infections no longer requires preventive therapy

Antiinflammatory - Bis-eugenol protects against inflammatory cytokine expression in macrophages

Antimicrobials - Human beta-defensin 3 possesses antibacterial activity against oral bacteria

Antisense Drugs - Company updates positive clinical data on multiple antisense drugs

Antitumor Drugs - Two CD95 tumor classes with different sensitivities to antitumor drugs

Aortic Valve Replacement - Clinical outcome of aortic valve replacement in the elderly is generally good

Apnea - Forehead Sensor assesses oxygen desaturation in anesthesia-induced apnea

Arrhythmias - Doctors use cryotherapy to treat irregular heartbeats

Assisted Reproductive Technology - Chinese Health Ministry bans test-tube technology for single women

Asthma - Air pollutants alone may cause asthma attacks

At-Risk Populations - Hispanics and limited-English speakers in California report worse health

Atherosclerosis - Excess body iron linked to elevated oxysterol levels

Atherosclerosis - Heat shock protein 60 mediates atherogenic effects of C. pneumoniae

Atherosclerosis - Infusions of synthetic HDL may remove plaque from coronary arteries

Atherosclerosis - Phase II data from study of ETC-216 show plaque accumulation can be reversed

Atherosclerosis - Stimulation of reverse cholesterol transport can result in regression of plaque

Atherosclerosis Research - Smooth muscle cells infected with Chlamydia pneumoniae increase MMP-1, MMP-3

Atrial Fibrillation - Nicotine exposure makes aging hearts more vulnerable

Atrial Fibrillation - Procedure cures AF by counteracting haywire electrical signals

Atrial Fibrillation - Scientists link heart condition with decrease in nitrous oxide

Atrial Fibrillation - Warfarin efficacy matched by new thrombin inhibitor ximelegatran

Atrial Myxoma - Myxoma of the right atrium could be due to fusion of giant cells

Atrial Septal Occluders - Evaluation of a large atrial septal occluder with cardiac MR imaging

Autoimmune Disease - Iloprost therapy given once a month at maximal dose improves systemic sclerosis

Awards - Moshe Oren named winner of NIH MERIT Award

Ayurvedic Medicine - Methanol extract of Bacopa monniera is antioxidant, protects from DNA damage

B Cell Maturation - Transgenic work shows lack of lambda5 doesn't fully impair pro-B cell maturation

B-Cell Function - Delta BAFF is an alternate splice isoform of BAFF that regulates B cells

Bacterial Taxonomy -  Nocardia puris characterized as a new species that can produce abscesses

Bacteriology - Fluorescent protein variants with enhanced brightness in bacteria developed

Bacteriology - Stannous chloride affects adhesive properties of C. diphtheriae strains

Benign Prostate Hyperplasia - URO-Stent approved in Russia

Benign Prostatic Hyperplasia - Uroxatral launched in U.S. to treat symptoms of benign prostatic hyperplasia

Benign Prostatic Hypertrophy - Benign prostatic hypertrophy drug available in U.S.

Bernard-Soulier Syndrome - Unresponsive thrombocytopenia patients may have GPIX mutation, Bernard-Soulier

Bile Duct Stones - Management of common bile duct stones: The state of the art in 2000

Bioinformatics - Genome-wide human genetic variation map complete

Bioinformatics Databases - IL-1, B7 protein families expanded due to sequence search; function is needed

Blood Glucose Monitoring - Results announced for continuous glucose monitor home-use trial

Blood Pressure and Cancer - Blood pressure and site-specific cancer mortality

Blood Safety - New Jersey blood bank shipping plasma to Scotland amid mad cow worries

Blood Substitute - Perfluorocarbon-based blood substitute undergoes phase I clinical trial

Body Composition - Methods to measure subcutaneous adipose tissue in children compared

Bone Loss - Simulated weightlessness changes bone characteristics in male and female rats

Bordetella Pertussis -  Bordetella pertussis CyaA binds CD11b at different site than catalytic one

Bovine Spongiform Encephalopathy - BSE test detects youngest case of Mad Cow disease in Japan

Brain Cancer Therapy - Ruta 6 induces selective apoptosis in glioma cells

Brain Mapping - Better imaging helps surgeons avoid damage to language functions

Breast Cancer - 14-3-3 Sigma positively regulates p53 and suppresses tumor growth

Breast Cancer - Bone sialoprotein overexpression fosters cancer cell metastasis in study mice

Breast Cancer - Breast cancer detection system receives marketing approval from FDA

Breast Cancer - Comparative transductions of breast cancer cells by three DNA viruses

Breast Cancer - Coping and posttraumatic growth in women with early-stage breast cancer

Breast Cancer - Danish researchers use image data software to help breast cancer research

Breast Cancer - Diagnosis of axillary nodal metastases by ultrasound-guided core biopsy

Breast Cancer - EZH2 is a marker of aggressive breast cancer

Breast Cancer - FDA gives approval for phase III registrational trial for breast cancer drug

Breast Cancer - Flavonoid intake and breast cancer risk: a case-control study in Greece

Breast Cancer - Health officials urge new mammograms for patients of New York clinic

Breast Cancer - Hpr6.6 protein mediates cell death from oxidative damage in MCF-7 breast cancer

Breast Cancer - Kodak gets FDA approval for mammography device

Breast Cancer - PET imaging still questionable as means of predicting chemotherapy response

Breast Cancer - Supreme Court justice battles disease from the bench

Breast Cancer - Surgical treatment for elderly breast cancer patients over age 70

Breast Cancer - The LeJour vertical mammoplasty pattern for skin-sparing mastectomy

Breast Cancer - iCAD, Inc. to distribute iQ Tabletop CAD System

Breast Cancer Screening - Cancer registry useful for Florida breast cancer early detection program

Breast Implant - Canadian study confirms women with implants require more medical care

Breast Implants - Causes of death among Finnish women with cosmetic breast implants, 1971-2001

Breast Reconstruction - Improving recipient vessel exposure during microvascular breast reconstruction

Breast-feeding - Fast-food chain apologizes to nursing mom

Breast-feeding - Lactation increases rate of wound healing, lowers stress hormone levels in mice

Burkholderia and Aspergillus -  Burkholderia cepacia pneumonia can occur in immunocompetent patients

Business & Finance - Blue Cross to reduce insurance rate hikes in Massachusetts

Business & Finance - County's health plan changed to boost local pharmacies

Business & Finance - Insurer continues to grow in shadow of federal fraud charges

Business & Finance - Insurer lowers earnings forecasts

Business & Finance - Medical office services co. acquired by healthcare technology & services firm

Business & Finance - Minnesota health plan to return $80 million in one-time rebate

Business & Finance - Minnesota insurer to lay off 130 workers

Business & Finance - Oklahoma city weighs hospital options

Business & Finance - Oklahoma ends three HMO contracts

Business & Finance - Pennsylvania hospitals announce merger

Business & Finance - State study finds commercial health insurers financially fit

Business & Finance - Two smaller New York health systems agree to merge

Business & Finance - Vermont hospital ending contract with large insurer

Business and Finance - Minnesota healthcare provider loses money again

CAD Risk - Higher blood levels of sitosterol may be dangerous

Cancer Caregivers - Measuring the burden, needs, and quality of life of informal caregivers

Cancer Cells - Choline phospholipid metabolism: A target in cancer cells?

Cancer Metastasis - Drosophila genetics can be a screening model for metastasis

Cancer Metastasis - Gene therapy containing p53 combines with CDDP to arrest liver tumor growth

Cancer Nursing - Onward in my journey - preparing nurses for a new age of cancer care

Cancer Proteomics - VEGF-C might act as a switch for tumor metastasis

Cancer Risk Factors - Hepatitis B virus genes promote liver cancer in chronic hepatitis C patients

Cancer Therapy - COX-2, cAMP and protein kinase A traverse integrins to regulate angiogenesis

Cancer Therapy - Genetic loci mark host response to angiogenic control

Cancer Therapy - Real-time imaging depicts how TRAIL can treat tumors

Cancer Therapy - Risk of second malignancy high after HDT and stem-cell autotransplantation

Cancer Treatment - Radiofrequency ablation being used to treat cancerous tumors

Cancer Vaccine - Tumoral immune resistance based on tryptophan degradation by enzyme

Cardiac Toxicity - Free radicals mediate cardiac toxicity induced by adriamycin

Cardiology - Electroporation improves DNAzyme delivery to vascular tissue

Cardiology - Ion channel-related gene expression during heart failure characterized

Cardiology - Menstrual cycle influences baroreflex heart rate control

Cardiology - Model for computing motion of mechanical heart-valve leaflets developed

Cardiology - Notch signaling activates heart regeneration in zebrafish

Cardiomyopathy - Cardiac patient with complications delivers healthy baby

Cardiomyopathy - Defibrillators may improve survival in nonischemic disease

Cardiovascular Disease - Adenosine receptor stimulation attenuates myocardial hypertrophy in mice

Cardiovascular Disease - Amino terminus of beta-ARK1 needed for beta-AR regulation

Cardiovascular Disease - Factors underlying social status-induced heart disease identified

Cardiovascular Disease - Oxidative stress assay predicts cardiovascular events in study

Cardiovascular Disease - Rho-kinase mediates angiotensin II-induced cardiovascular hypertrophy in rats

Cardiovascular Disease - Role of kinin system in cardiovascular disease reviewed

Cardiovascular Disease - Serum paraoxonase does not mediate cardioprotective effects of red wine

Cardiovascular Disease Therapy - Enoxaparin improves vascular reactivity in aged and diabetic rats

Carotid Artery Stenosis - CT angiography validates duplex sonography of carotid artery stenosis

Cell Biology - Endostatin uses specific sulphates for endothelial heparan sulphate binding

Cell Biology - Growth factor controls how endothelial cells recruit vascular muscle cells

Cell Signaling - Newly discovered pathway provides insight into heart disease

Cell Therapy - Study: Bone marrow may aid damaged hearts

Cell Therapy - World's first integrated system to increase safety of cell therapy

Cervical Cancer - KCl cotransport is an important modulator of cervical cancer growth and invasion

Cervical Cancer - National coverage initiated for DNAwithPap test

Cervical Cancer - Radical hysterectomy increases risk of impairing women's sexual function

Cervical Cancer - The development of high-dose-rate brachytherapy for cervical cancer in Japan

Chagas Disease -  Trypanosoma cruzi antigens elicit strong humoral immune response in mice

Chemotherapeutic Agents - Acid pH affects the distribution of chemotherapeutic agents in vitro

Childhood Cancer - Vitamin K is not associated with the development of childhood cancer

Children's Health Insurance - Tens of thousands of Texas children off CHIP insurance rolls

Cholera - PFGE analysis useful in epidemiological study of Vibrio cholerae

Cholesterol - Niaspan launched in the United Kingdom

Chronic Hepatitis C - Tissue regeneration may drive HCV recurrence after liver transplantation

Chronic Ischemia - Genetic background influences how VEGF promotes new vessel growth

Chronic Kidney Disease - Company launches trial of gene-modulated tissue production of protein

Clinical Trial - Challenges of recruitment and retention in multisite clinical research

Cloning - FDA urged to base animal cloning policy on long-term research

Cloning - Lots of animals cloned, but nature doesn't make it easy; Monkeys? Forget it

Cloning Policy - U.N. delays any consideration of treaty to ban human cloning for 2 years

Co-Morbid Disease - New TB vaccine shows promise in people with AIDS

Cognition - Ginkgo biloba may help improve memory

Colitis - Substance P regulates Th1-type colitis in IL-10 knockout mice

Collaborations - Alliance targets siRNA research using GeneChip technology

Collaborations - Alliance with the Cleveland Clinic uses imaging system in cancer research

Collaborations - AlphaNet to provide services to emphysema patients who rely on Zemaira

Collaborations - Company gets $20M from Bristol-Myers Squibb as part of Basulin project.

Collaborations - Haemonetics announces intent to sign distribution agreement with French firm

Collaborations - IDI inks agreements regarding its real-time diagnostic products

Collaborations - Joint development agreement signed for MRI devices

Collaborations - LION bioscience completes first joint products with partner

Collaborations - Marketing agreement signed for Collagenase Santyl Ointment

Collaborations - Medarex announces achievement of milestone in agreement

Collaborations - Miikana Therapeutics inks strategic alliance for antibody development

Collaborations - Partnership with Infectio Diagnostics restructured

Collaborations - Pennsylvania partnership announces agreement to build relationship with Roche

Collaborations - Preliminary agreement for Sucanon sales in Mexico concluded

Collaborations - Research agreement signed for testing of topical anti-herpes formulations

Collaborations - Research alliance to combine reverse transfection and siRNA

Colon Cancer - High expression of CD55 by colorectal cancers is predictive of low survival

Colon Cancer - Modified de Gramont with oxaliplatin in treatment of advanced colorectal cancer

Colon Cancer - Motility of colon cancer cells: modulation by CD44 isoform expression

Colon Cancer - Probiotic bacteria may inhibit colon cancer

Colorectal Cancer - 2003 survey shows limited awareness of cancer prevalence

Colorectal Cancer - Multivitamin use and colorectal cancer incidence in a U.S. cohort

Colorectal Cancer - NSAIDs inhibit colorectal neoplasia

Colorectal Cancer - Rates of colon and rectal cancers are increasing in young adults

Complementary and Alternative Medicine - Soy isoflavones help postmenopausal women with low bone mass retain density

Compliance - Diabetes management improves when patients, doctors agree on treatment goals

Congenital Heart Defects - Ethnicity does not affect accuracy of molecular test for 22q11.2 deletion

Congenital Heart Defects - Gene raises risk of neurologic problems after infant heart surgery

Congestive Heart Failure - Big cut in heart failure problems seen after 1 hour of education

Congestive Heart Failure - Care inconsistent for heart patients

Congestive Heart Failure - Future bright for cardiac care

Congestive Heart Failure - Low infection rate seen in Arrow Lionheart European trial

Conscious Sedation - Company reports positive phase II clinical trial results of Aquavan Injection

Contraception - A new WHO study shows hormonal male contraception prevents pregnancy

Contraception - FDA approves first chewable birth-control tablet for women

Coronary Artery Bypass - Intraoperative angiography for quality control in MIDCAB and OPCAW

Coronary Artery Bypass - Normal and delayed hospital discharge after index isolated Coronary Artery Bypass

Coronary Artery Bypass - Off-pump coronary artery bypass grafting: the myth, the logic and the science

Coronary Artery Bypass - Reconstruction of infected deep median sternotomy wound after coronary artery bypass

Coronary Artery Bypass - Successful intracoronary bone marrow cell transplant leads late-breaking clinical trials

Coronary Artery Disease - Variable distal microvascular resistance linked to heightened CAD severity

Coronary Heart Disease - Depressive symptoms - not disease severity - determine quality of life for CHD patients

Coronary Heart Disease - Simple tests could signal and prevent heart disease in women

Corporate Update - GenSci announces name change, delisting from TSX and listing on NEX

Corporate Update - Pharmaceutical company announces restructuring of operations

Corporate Update - Protein engineering firm moves facilities

Correctional Health - University to provide healthcare to jail inmates

Cosmetic Surgery - Study: Mandatory reporting of adverse incidents could enhance safety

Critical Care - Vital sign device improves resuscitation monitoring

Critical Care Medicine - Pressures' variations comparable as blood loss indicators in mechanically ventilated patients

Cystic Fibrosis -  Ralstonia respiraculi isolated from lungs of cystic fibrosis patients

Cystic Fibrosis - Genetic aberration helps explain variation in contraction of CF

Cytokines - TNF expression in TMJ inflammation determined using microarray analysis

Cytology Fixation Method - Cytology smears retain best antigen reactivity if directly fixed in 95% ethanol

DNA Damage - Mechanism of apoptotic resistance of human osteosarcoma cell line elucidated

DNA Vaccine - Candidates for immunization regimens using DNA vaccines described

DNA Vaccine - DNA vaccine induces protective capsular polysaccharide antibody response

DNA Vaccine - Heat shock protein-mediated antigen targeting increases DNA vaccine potency

DNA Vaccine - Mucosal immunization with DNA vaccines reviewed

DNA Vaccine - Technical issues in construction of nucleic acid vaccines reviewed

Dementia - New technique helps shed light on influence of ministrokes

Dementia - Role of matrix metalloproteinase-9 in dementia outlined

Dendritic Cell Subsets - CD11b+ DC from Peyer patch induce the highest B cell IgA secretion via IL-6

Depression - Among elderly, depression is more prevalent in Hispanics and blacks

Depression - Study links depression with sleep apnea

Dermatology - Nonresponsive bullous pemphigoid may be bullous scabies

Dermatology - Survey finds women overwhelmed by antiaging treatment options

Dermatology - Vesicular pemphigoid in children and teens may mimic herpes infection

Developmental Biology - Low lead levels can affect development of brain cells

Diabetes Genomics and Genetics - Novel gene for neonatal diabetes maps to chromosome 10p12.1-p13

Diabetes Risk Factors - Diabetes underdiagnosed in coronary artery disease patients

Diabetes Surgery - Immunological perspectives of islet transplantation reviewed

Diabetes Therapy - Lagerstroemin activates insulin receptors

Diabetes Therapy - Lessons from nurses' viewpoint on diabetes care programs presented

Diabetic Nephropathy - Oral cavity is source of infection in diabetic kidney recipients

Diabetic Neuropathy - Replacing C-peptide may delay development of diabetic neuropathy

Diagnostics - Guidelines for assessing immunotoxicity released

Diagnostics - Imaging company inks agreement with the Rumbaugh-Goodwin Institute

Diagnostics - In organ transplant complications, histology is often needed to assess cause

Diagnostics - Many tests for respiratory diseases are not based on good evidence

Diagnostics - Peripheral blood mononuclear cells express different genes in kidney cancer

Diagnostics - Program for predicting protein structures from amino acid sequence developed

Diagnostics - Tumor oxygen use, hypoxia, can be observed by MRI with FREDOM

Dialysis - Patient enrollment initiated in study of vascular sealant product

Diet and Nutrition - Effect of sugar consumption on regulation of food intake reviewed

Diet and Nutrition - IGF-I activity may be a key determinant of stroke risk

Diet and Nutrition - New research has identified zinc cutoff values for premenopausal women

Dilated Cardiomyopathy - Infection can lead to immune attack on heart

Disc Replacement - Long-term flexion-extension range of motion of the Prodisc disc replacement

Disc Replacement - Prospective study evaluating total disc replacement - preliminary results

Disease Management - Quality improvement program enhances heart care, closes gender gap

Disease Prevention - More risk factors for heart disease increase Medicare cost

Down Syndrome - Blood test screening reduces need for amniocentesis

Down Syndrome - Chromotest updates presented at American Society of Human Genetics meeting

Drosophila - Fruit fly scientists capture $20 million grant

Drug Abuse - Drug use climbed in the U.S. workforce in the first half of 2003

Drug Abuse - Family factors affect drug use by Mexican American teens

Drug Abuse - Inhalant nitrite alters hepatic angiogenic gene expression in mice

Drug Development - 8-Quinolinamines and their pro prodrug conjugates show promise as antimalarials

Drug Development - A new swine uterus perfusion system should advance physiological research

Drug Development - Antitubercular compounds isolated from Caesalpinia pulcherrima root

Drug Development - Devil's claw yields potent, selective antimalarial agents

Drug Development - HIF-1 may be target for future cancer and heart disease drugs

Drug Development - Midwest research looks at cows to produce vaccines

Drug Development - Positive study results released on GPCR targeted library

Drug Discovery - Company introduces IMAP Progressive Binding System and nine new substrates

Drug Discovery - Company reaches milestones in two research alliances with Baxter Healthcare

Drug Discovery - Lilly purchases integrated cellular screening system

Drug Discovery - Pharmaceutical company extends new R&D model with seventh CEDD

Drug Discovery - Research agreement supports computer-assisted molecular design of medicines

Drug Discovery - SBIR grant supports company's work with computer models of cellular metabolism

Drug Resistance - Leptin gene therapy doesn't overcome diet-induced obesity

Dyslexia - Reading problem may involve both vision and hearing

Dyslipidemia - Company announces results of clinical trial with HE2200

ER Overcrowding - Baptist launches campaign focused on emergency rooms

Early Detection - New systems could find chemical residues, mad cow disease and SARS

Early Lyme Disease -  Borrelia burgdorferi induces inflammatory cytokines during erythema migrans

Eating Disorder - Pharmacotherapy of eating disorders reviewed

Eating Disorders - Family dysfunction foreshadows bulimia nervosa and other psychoses

Electronic Medical Records - Ob-gyn practice says EMR improves workflow, patient care

Embryology - Human mucins 1, 3, 6 normal in fetal kidney; MUC3, MUC6 absent in diseased organ

Employer-sponsored Health Insurance - Healthcare inching up on West Virginia legislators' 2004 agenda

Employer-sponsored Health Insurance - Police union files grievance over insurance changes

End-of-Life Care - Assisted dying and end-of-life symptom management

Endocrinology - C-terminal pro-ghrelin peptides in human plasma; altered during cardiovascular disease

Endocrinology - Effects of aging and stress on hippocampal structure and function described

Endocrinology - Estrogen-induced vessel remodeling protects the cardiovascular system

Endocrinology - Genetic mutations resulting in delayed puberty are focus of study

Endocrinology - Interferon improves insulin dynamics in chronic hepatitis B and C responders

Endocrinology - Sex differences exist in effect of obesity on serum gonadotropin levels

Enterococcus Faecalis -  E. faecalis gains entry into enterocytes by means of Asc10 functional domain

Environmental Exposure - Skin aging is an area of concern in developed countries; therapy is available

Environmental Health - Individually tailored pest management programs reduce pediatric health risks

Environmental Health - Insecticide metabolites determined in human urine by GC-MS

Environmental Toxins - For smokers, air pollution is a drag on the heart

Epilepsy - Medicare reimbursement rates posted for VNS therapy

Epstein-Barr Virus - Severe pneumonitis, cerebral hemorrhage is a risk with Epstein-Barr virus

Erectile Dysfunction - Primary endpoints met in phase IIb study of erectile dysfunction drug

Evolutionary Biology - Two worms are better than one for studying divergence of species

Facilities - HMA completes acquisition of five nonurban hospitals from Tenet Healthcare

Fatty Liver Disease - Long-term rosiglitazone improves the markers of nonalcoholic steatohepatitis

Female Genital Mutilation - International conference calls for an end to circumcision practice

Femur Fractures - The prosthesis nail - a new, stable fixation device for periprosthetic fractures

Finance - Actimmune maker announces third quarter financial results

Finance - Ambulatory surgery centers report 19% increase in revenues

Finance - Assay maker reports loss of $0.14 per share

Finance - Biopharma company announces exercise of underwriter's over-allotment option

Finance - Biopharma company announces third quarter 2003 financial results

Finance - Biotech company reports 6% increase in sales

Finance - Biotech company reports loss of $0.21 per share

Finance - Biotech firm raises $22M in private equity transaction

Finance - CardioSEAL maker announces increased revenue, decreased losses in third quarter

Finance - Cell therapy company launches direct stock purchase program

Finance - Chemistry drug company reports 41.6% increase n revenue

Finance - Company authorizes up to $2 million for repurchase of its common stock

Finance - Company offers Cialis update and reports net loss for third quarter

Finance - Company reports record first quarter sales of VScan test kits

Finance - Device company's executives enter into Rule 10b5-1 trading programs

Finance - Diagnostic imaging center operator announces record third quarter revenues

Finance - Diagnostics company reports third quarter results; bladder cancer test revenues up 87%

Finance - Drug delivery company announces third quarter 2003 results

Finance - Drug delivery company reports loss of $0.31 per share

Finance - Drug-screening company announces third-quarter results on par with prior year

Finance - Electrosurgical products company's stock listed on Amex

Finance - Enzyme Therapy maker reports quarterly loss of $0.33 per share

Finance - Flavin Ventures announces funding of proteomic service provider

Finance - Follow-on offering reported by pharmaceutical firm; guidance issued

Finance - Gastrointestinal-focused pharma reports profitable Q3, with $1.2M in net income

Finance - Genaera announces third quarter 2003 financial results

Finance - Generic drug maker reports 38.9% increase in sales

Finance - Genomics company reports loss of $0.01 per share

Finance - Genomics company reports loss of $0.35 per share; provides pipeline update

Finance - Health Net's third quarter EPS income from continuing operations climbs 35%

Finance - HealthSouth in negotiations with bondholders; gets notice of technical default

Finance - Healthcare products provider reports record third quarter results

Finance - Hemodialysis company reports per share loss of $0.19

Finance - Immunology-focused company reports third quarter losses

Finance - Immunotherapeutics company reports $7.4M in revenue

Finance - Inamed announces 3-for-2 stock split

Finance - Inflammatory diseases drug maker files resale registration statement with SEC

Finance - Insulin system maker reports loss of $0.08 per share

Finance - Interleukin Genetics acquires equity interest in British start-up

Finance - Lipid-focused company reports improved results in third quarter

Finance - MAMSI announces third quarter earnings

Finance - Medical device company closes on $23.5 million of series D financing

Finance - Medical device firm reports 9% increase in revenue

Finance - Medical device maker announces move to Amex

Finance - Metabolic disease drug maker reports loss of $0.40 per share

Finance - Microcatheter maker reports increased sales in third quarter

Finance - Microfluidics company reports loss of $0.37 per share

Finance - Molina Healthcare reports positive results for third quarter

Finance - NHC reports third quarter earnings up 23.2%

Finance - National Research Corp. achieves highest quarterly revenues in its history

Finance - Neugene maker reports net loss of $0.15 per share

Finance - Neurological disease biotech company reports loss of $0.07 per share

Finance - Offering of 35M shares closed by pharmaceutical firm

Finance - Oncology company reports loss of $0.19 per share

Finance - Oncology drug maker reports $0.08 per share loss

Finance - Orthotics company reports profitable quarter

Finance - Pain management drug maker announces pricing of common stock

Finance - Pain medication maker reports royalty income increased 23%

Finance - Pain medicine company raises US$32 million in series C round

Finance - Pharmaceutical company announces third quarter 2003 financial results

Finance - Pharmaceutical company boosts sales by 13% worldwide

Finance - Pharmaceutical company reports 63% increase in net income in third quarter

Finance - Pharmaceutical company reports net loss in third quarter 2003

Finance - Pharmaceutical company reports record third quarter revenues; total revenues up 24%

Finance - Physician services provider reports record third quarter results

Finance - Polymer implant maker reports record Q3 revenues; revenues increase 36%

Finance - Proteomics device maker reports 12% increase in revenue

Finance - Radiopharmaceuticals company reports 46% revenue growth

Finance - Seasonale maker reports 41% increase in revenue

Finance - Sexual dysfunction drug maker completes $2M financing

Finance - Small molecule drug developer reports income of $0.11 per share

Finance - Specialty pharmaceutical company reports record quarterly revenues

Finance - Third quarter service revenue rises 25% at imaging company

Finance - Tissue processing company reports loss of $0.24 per share

Finance - Tissue, bone repair company posts 27% increase in revenue

Finance - VAP-focused pharmaceutical company increases cash resources, meets milestones

Finance - Woman's health company reports increased third quarter revenues

Fitness - Researchers study physical and mental impacts of exercise on the brain

Food Safety - Amount and type of shadecovers slows degradation of insecticide carbaryl

Food Safety - The Bacillus subtilis strain used in biological control can infect cabbages

Food-borne Illness - Filtration membrane applied to IR spectroscopic discrimination of bacteria

Forensic Medicine - Laser microdissection enhances the recovery of DNA from sperm on lab slides

Fungal Infections - Ravuconazole, voriconazole, and albaconazole are active against Chaetomium

Gastric Cancer - Broad potential reported for R1549 highlighted by favorable tolerability profile

Gastric Cancer - Detection of p53 mutations in precancerous gastric tissue

Gastroenterology - Outcomes with hepatitis C- and B-core antibody-positive grafts are good

Gender and Medicine - Heart attacks appear to have more serious impact on women than men

Gene Delivery - Rearranged cell activity enhances how RAD50 gene therapy affects angiogenesis

Gene Expression - Company introduces Expression Snapshot mRNA Archiving Kit

Gene Rearrangement - TCR gene rearrangement can occur outside thymus, in the human small intestine

Gene Sequencing - First 60-mer microarray for rice commercialized

Gene Transfer - A novel amplicon system identifies obstacles to new therapies

Gene Transfer - SMAD4 gene therapy halts the invasiveness of pancreatic adenocarcinoma cells

Genetic Disorder - Capillary morphogenesis protein mutation causes juvenile hyaline fibromatosis

Genetic Engineering - ONYX-015 augments radiotherapy directed against thyroid cancer cells

Genetic Mutations - Genetic and epigenetic alterations as hallmarks of the intricate road to cancer

Genetic Screening - Genetics company presents new data relating to prenatal and genetic testing

Genetics - Study: Newborn screening cost-effective in detecting MCADD

Genomics - Bioarray service laboratory launches RNA isolation service

Genomics - Genomic instability and cancer

Genomics - NHGRI funds large-scale genomic sequencing project

Genomics and Genetics - Guidelines for demonstrating genetic causation in diseases proposed

Genomics and Genetics - Human genes involved in HIV life cycle have high alternate splicing rates

Genomics and Genetics - P2X7 receptor gene polymorphism does not affect survival in leukemia

Geriatrics - 10 common healthcare mistakes made by seniors

Geriatrics - Bisphosphonates prevent bone fractures in the elderly

Geriatrics - Significant shortfalls found in recommended medical care for vulnerable seniors

Giardiasis - Oral immunization with Giardia duodenalis protein inhibits shedding of cysts

Glucose Monitoring - FDA clears GlycoMark test for people with diabetes

Glucose Monitoring - Study data announced on continuous noninvasive glucose monitor

Gynecology - PTEN overexpression squashes the migration of ovarian cancer cells

HIPAA Compliance - MedAptus' Charges In Hand 4.1 released

HIV Diagnostic - Investigational device exemption application submitted for HIV-1 test

HIV Gene Therapy - Gene vector for HIV cleared to begin phase I/II trial

HIV Vaccine - Preclinical development program initiated for new HIV vaccine candidate

HIV and AIDS Prevention - HIV-related preventive behavior in U.S. improves in many population groups

HIV-1 Antibody Tests - HIV-1 antibody test receives award from science magazine

HIV/AIDS Dementia - Oxidative stress likely involved in early HIV Tat-related neurodegeneration

HIV/AIDS Diagnostics - Despite high cost, PCR assay for group O HIV suitable for use in endemic areas

HIV/AIDS Diagnostics - Heat-denatured signal-amplified HIV p24 assay suitable for use in developing areas

HIV/AIDS Diagnostics - Novel molecular HIV test has single-copy sensitivity for viral RNA

HIV/AIDS Epidemiology - Children left motherless by AIDS in U.S. drops from 1978 to 1998

HIV/AIDS Immunotherapy - IL-7 safely stimulates T-cell renewal in SIV-infected macaques

HIV/AIDS Lipodystrophy - Elevated cytokine levels in adipose tissue suppress adiponectin output in HALS patients

HIV/AIDS Proteomics - HIV Nef signaling - but not trafficking - underlies impaired T-cell development

HIV/AIDS Proteomics - HIV Nef's ability to downregulate MHC-I molecules key to viral immune escape

HIV/AIDS Proteomics - HIV Tat interacts with distinct proteasomal alpha and beta subunits

HIV/AIDS Risk Factor - Alpha1-antitrypsin gene mutations may raise HIV infection risk

HIV/AIDS Therapy - Educational program fails to improve adherence to HIV treatment in minority patients

HIV/AIDS Therapy - Expanded HIV care needed for aborigines and women in Canada

HIV/AIDS Therapy - HAART effective for pediatric HIV patients

HIV/AIDS Therapy - LC/MS/MS assay suitable for measuring atazanavir levels in peripheral blood

HIV/AIDS Therapy - Long-term HAART does not lead to full T-cell recovery

HIV/AIDS Therapy - Rituximab shows promise for HIV patients with Castleman disease

HIV/AIDS Transmission - Whole milk component of breast milk carries highest HIV load

HIV/AIDS Vaccine - Attenuated FIV vaccine protects against systemic or mucosal challenge

Hallucinations - Pale retina inclusions in dementia with Lewy bodies may cause hallucinations.

Hand Surgery - Society launches public awareness campaign

Hantavirus Epidemiology - Hantavirus in Brazilians may be asymptomatic or cause cardiopulmonary syndrome

Head and Neck Cancer - Physiological and molecular genetic alterations in head and neck cancer

Headache and Migraine - 5-HT1F receptor agonists effective for acute migraine treatment

Health Benefits - AdvancePCS enhances consumer-directed pharmacy benefit services

Health Education - Hairstylists recruited to promote good health

Health Insurance - Consumer-driven healthcare plan projects membership to exceed 320,000

Health Plan Benefits - Insurer launches nursing program directed at acute or chronically ill members

Health Statistics - Louisiana, Oklahoma rank low in new study of state social health

Health Statistics - Nevada lawmaker says state isn't good for women's health

Health Statistics - Study ranks Iowa tops for social health

Health Statistics - U.K. drops to 18th place in study of industrialized countries' health systems

Healthcare & Politics - Lieberman proposes tax credits, deductions for long-term care

Healthcare & Politics - Oklahoma governor eyes expanded healthcare coverage in 2004

Healthcare & Politics - Presidential-hopeful Edwards outlines healthcare plan

Healthcare & Politics - West Virginia's gubernatorial candidates divided over healthcare

Healthcare Access - China offers free treatment to AIDS patients with financial woes

Healthcare Access - Mexico asks state leaders to provide services for illegal immigrants

Healthcare Benefits - 85 million Americans had no health insurance at some point during 1996-1999

Healthcare Benefits - Grant will fund insurance for low-income Virginians

Healthcare Benefits - Health insurance an impossible dream for many

Healthcare Benefits - Healthcare safety net has significant limitations at hospitals

Healthcare Benefits - New health coverage offered for Montanans without insurance

Healthcare Economics - Alabama governor to propose changes in state worker insurance

Healthcare Economics - Availability drives use of medical technology and healthcare costs, study says

Healthcare Economics - Maryland summit meeting focused on seeking solutions to healthcare crisis

Healthcare Economics - Report says underfunding hampers healthcare delivery in Vermont

Healthcare Economics - Report: Premiums could push poor families off Medicaid

Healthcare Economics - Wyoming officials defend health department's high-cost budget items

Healthcare Fraud - Insurers stepping up fight

Healthcare Reform - City to prepare universal healthcare plan after residents pass referendum

Healthcare Reform - Groups try to jump start debate on universal healthcare in Minnesota

Healthcare Reform - U.S. healthcare cost, quality problems require government leadership

Healthcare Worker Injuries - Agreement signed to distribute NeedleZap to medical, dental markets

Heart Attack - Nitric oxide mediates relaxin-induced suppression of endothelial adhesion

Heart Attack - Unusual fatigue, other symptoms could warn of impending heart attacks in women

Heart Disease - Albumin reduces mortality in coronary artery bypass graft surgery

Heart Disease Risk Factor - Role of immune processes in diabetic macrovascular disease reviewed

Heart Disease Therapy - Novel methods for modifying coronary disease discussed at AHA conference

Heart Failure - ADHERE patient registry reaches 100,000-case milestone

Heart Failure - Endothelin has differential effects on Kv1.4 and Kv4.3 K+ currents

Heart Failure - Medicare approves permanent support from assist device for heart failure

Heart Failure - Neither carvedilol nor bisoprolol reduce oxidative stress in CHF patients

Helicobacter Pylori - Toxigenic and nontoxigenic H. pylori outer membrane vesicles increase IL-8

Hematologic Malignanc - Bone marrow evaluation in pediatric patients

Hematologic Malignancies - Chromosomal translocations in human malignant hematopoiesis

Hematologic Malignancies - Epoetin alfa therapy for patients with hematologic malignancies and mild anemia

Hematology - Endothelial progenitor cells respond to shear stress with accelerated activity

Hematology - Silver(I) ion exerts unusual aggregation effects on hemoglobin

Hematopoietic Cell Transplant - Keeping DC immaturity may induce tolerance for transplant of hematopoietic cells

Hematopoietic Cytokines - Cytokines are recognized by gp130 by thermodynamics, independent of structure

Hemolysis - Unfolding of Vibrio cholerae hemolysin induces toxin monomer oligomerization

Hemophilia - Supplement filed for approval of needless device used with Kogenate FS

Hemorrhagic Complications - Non-hemophiliacs can have acquired, temporary hemorrhagic factor VIII syndrome

Hepatic Cancer - The proto-oncoprotein c-Fos negatively regulates hepatocellular tumorigenesis

Hepatitis A Virus - New study finds universal vaccination would prevent disease and save lives

Hepatitis B Vaccine -  Aspergillus niger effective host for virus-like particle production

Hepatitis C Virus - Companies enter hepatitis C virus license agreement

Hepatitis C Virus - Pharmaceutical company to initiate phase III clinical trials for Viramidine

Hepatitis C Virus - Researchers reveal essential component of immunity to liver-destroying virus

Hepatitis Therapy - Nasal or rectal administration of glycyrrhizin offers good bioavailability

Hepatitis Virus - Interferon-alpha down-regulates collagen production and stems liver fibrosis

Histopathology - Transplant recipients may have relevant histological changes in all tissues

Hormone Replacement Therapy - MPA component of HRT counteracts cardioprotective effects of estrogen

Hormone Therapy - Survey validates women's confusion about safety of menopausal hormone therapy

Human Growth Hormone - A new LHRE reporter gene assay can measure human growth hormone bioactivity

Human Herpesvirus 7 - Glycoproteins B, H of human herpesvirus 7 appear to have few polymorphisms

Hunter Syndrome - Long-term phase I/II data from TKT's I2S trial offer promise

Hypertension - Birth weight does not influence blood pressure in childhood

Hypertension - ET-1 mediates cardiac MMP upregulation during onset of hypertension

Hypertension - Emory scientists find oral tetrahydrobiopterin can reduce high blood pressure

Hypertension - More aggressive treatment in women yields similar results to men

Hypertension - Overweight girls' blood pressure responds better to stress than overweight boys

Hypertension - Physicians report progress in two epidemics of secondary hypertension

Hypertension - Region of chromosome 1 important in blood pressure regulation

Imaging - Cardiac MRI detects thinned heart muscle previously deemed unsalvageable

Immune Thrombocytopenia - I.V. anti-D safe for pregnant moms with thrombocytopenia purpura; fetus okay

Immune Tolerance - Stat3 molecule can regulate switch from T cell activation to immune tolerance

Immunoglobulin - New IGIV, Gamunex, now available

Immunoglobulin Superfamily - Evolution has created many membrane proteins with immunoglobulin-like domains

Immunogold Histology - Mathematics helps determine colocalization of labeled proteins in EM

Immunology - Antisense blockade of Stat5a/b promotes the apoptosis of lymphoid cells

Immunology - IGSF4, a new intercellular adhesion molecule with diverse functions

Immunology - Ischemia, alloantigen, and gene transfer induce cardiac genes differentially

Immunology - Transparent fish provide window on blood formation and marrow transplantation

Immunosuppressants - Stevastelin synthesis advances; natural-like product yet to be achieved

Immunosuppressive Drugs - Immunosuppressants influence dendritic cells; can affect tolerance induction

Infant Mortality - Waiting 3 years between births could reduce infant mortality by 24%

Infectious Disease -  C. pneumoniae tyrP genotype determines respiratory, cardiovascular effects

Infectious Disease - Bacterial infection in pregnancy Pap smears signals a risk for complications

Infectious Prions - Prototype leukocyte reduction filter reduces infectious prions in study

Infertility - Chlamydial infection diminishes the acrosomal activity of sperm

Inflammatory Bowel Disease - Protein may play central role in IBD

Influenza - Report: Influenza drug market sales to reach $2.5 billion in 2012

Influenza - Team developing "Flu Chip" for fast, accurate diagnosis

Influenza - Test compound 100% effective in influenza A animal prophylaxis experiment

Information Technology - AllHealth offers interactive TV, reinvents patient care

Information Technology - AstraZeneca purchases in vitro technology application

Information Technology - Custom lab system designed for breast cancer project

Information Technology - Keane and ArcStream launch wireless healthcare solution

Information Technology - Licensing agreement signed for osteoporosis monitoring system

Information Technology - LifeTree launches enhanced electronic data capture system for clinical research

Inherited Fungal Susceptibility - Serum protein carbonyl groups are lower in familiar chronic nail candidiasis

Injury Prevention - Age-related decrease in physical ability may be in the genes

Injury Prevention - Introcan Safety IV Catheter helps reduce needle sticks

Injury Prevention - Parents favor speed bumps to protect child pedestrians

Injury Prevention - Parents' input, new license step may cut teen car wrecks

Injury Prevention - UF researchers say speeding associated with gambling, drug use in teens

Inoperable Liver Cancer - Liver cirrhosis with inoperable liver cancer treated by intratumor ethanol, IL-2

Insulin - Two novel fast-acting insulins engineered

Insulin Delivery - Positive results reported on long-acting injectable insulin

Insulin Delivery - Positive results reported on pulmonary-delivered insulin study

Insulin Infusion - Animas IR 1200 receives FDA approval

Interstitial Cystitis - Reduced proteoglycans could trigger interstitial cystitis; chondroitin sulfate may help.

Interstitial Cystitis - Researchers pinpoint possible cause of chronic bladder disease

Intestinal Disease - Celiac disease should be treatable by gluten-free diet and better immunotherapy

Intravascular Therapy - 510k market clearance granted for catheters with thermal regulation system

Islet Transplantation - Phase I/II study initiated treating diabetes with encapsulated replacement islets

Joint Development - Generic and branded products expected from joint development in next 4 years

Junk DNA - LINEs censor themselves to avoid trouble

Keratinocyte Carcinoma - Keratinocyte carcinoma is the most common cancer in the United States

Kidney Cancer - Reduced-intensity stem-cell transplantation may slow RCC progression

Laser Eye Surgery - Pennsylvania medical groups warn consumers against procedure at mobile clinics

Laser Vision Correction - Study: Better results achieved when femtosecond laser replaces microkeratome

Lassa Fever - Researchers receive $1.68M grant for research on Lassa fever treatment

Left Ventricular Failure - Trial planned for left ventricular assist systems as destination therapy

Legal Issues - Five ex-HealthSouth workers to be sentenced for accounting fraud

Legal Issues - Florida Medicare fraud case cost taxpayers $14 million

Legal Issues - Former Blue Cross official sentenced to prison for $14.1 million billing scheme

Legal Issues - Insurer's CEO fined $250 for lobbying

Leishmania - Surface metalloprotease gp63 is released by Leishmania species into culture

Leishmaniasis - Present status of antileishmanial vaccines reviewed

Leptin Studies - Leptin and insulin modulate nutrient partitioning and weight loss

Leptin Studies - Leptin polymorphism in cows increases meat fat but not milk fat

Letter to the Editor - WellPoint/Anthem proposed merger

Leukemia - Chromosomal abnormalities in secondary myelodysplastic syndromes and leukemias

Leukemia - Cytogenetic findings in adult de novo acute myeloid leukemia

Leukemia - DNA microarray stem cell analysis can differentiate de novo and MDS-related AML

Leukemia Therapy - Cyclosporine and IFN-gamma treatment after auto-SCT improves outcome

Leukemia Therapy - Cytoreduction may be needed for curative SCT in CML patients

Leukemia Therapy - Imatinib treatment can improve SCT outcome in Ph+ ALL patients

Leukemia Therapy - Persistent iron overload common in long-term AML survivors after stem-cell autografting

Leukocyte Function - Some integrin antagonists bind the beta2 subunit I domain, directing signals

Lipid Studies - Role of HDL receptor SR-BI reviewed

Liver Transplantation - Liver transplantation across ABO blood groups in children

Lung Cancer - Adenoviral overexpression coupled with lab assays can uncover gene profiles

Lung Cancer - Bronchoscopic insertion of Gianturco stents for the palliation of lung cancer

Lung Cancer - Chymase positivity may predict outcomes in patients with localized lung cancer

Lung Cancer - Gemcitabine with cisplatin or epirubicin in advanced non-small-cell lung cancer

Lung Cancer - Group highlights what women don't know about their top cancer killer

Lung Cancer - Menthol cigarettes and risk of lung cancer

Lung Cancer - Proteomic approaches to biomarker discovery in lung cancers by SELDI technology

Lung Cancer - Safety and efficacy of low-dose docetaxelin advanced non-small cell lung cancer

Lung Cancer - Tumor dimension and prognosis in surgically treated lung cancer

Lung Cancer - Tumor size predicts survival in patients with lung cancer

Lung Cancer - Weekly carboplatin and paclitaxel in elderly non-small-cell lung cancer patients

Lung Cancer Mutation - Lung tumor suppressor TSLC1 binds MPP3; mutation in TSLC1 disrupts cell adhesion

Lymphoma - Waldeyer ring lymphomas: Treatment results and prognostic factors

Lymphoma Therapy - Involved field radiation therapy raises TRM risk in stem-cell transplant recipients

Lymphoma and Myeloma - Cytogenetic abnormalities in malignant lymphoma and multiple myeloma

MHC-I Antigen - Chaperonin TRiC is essential for antigen presentation, protecting MHC-I antigen

Maesa Lanceolata Benzoquinones - Antitumor, antioxidant effects seen in vitro for some alkylated benzoquinones

Malaria Diagnostics - Fluorogenic assay provides improved P. falciparum genotyping

Malaria Pathogenesis - Hemazoin augments nitric oxide production by macrophages

Malaria Proteomics -  Plasmodium falciparum Rad51 homologue identified

Malaria Therapy - Combination antimalarial therapy can slow spread of drug resistance

Malaria Therapy - Novel beta-diketonate improves synthesis of trioxane antimalarial agents

Malaria Therapy - Oxidative stress underlies antitumor activity of artesunate

Malaria Vaccine -  P. falciparum SERA protein peptide analogues protect against malaria

Malaria Vaccine - Protective effect of 6746 SERA peptide against malaria linked to alpha helix

Malignant Melanoma - Company files for European approval to market Ceplene

Manufacturing - Company announces medical device assembly equipment contracts

Market Analysis - Aging boomers are moving target in $17B U.S. arthritis market

Market Analysis - Anesthesia monitoring technology leading market growth

Market Analysis - Drug development costs reach all-time high

Market Analysis - Medicaid-focused plans, commercial plans find similar uses for IT

Market Analysis - Pharmaceutical companies are capitalizing on biomarker potential

Market Analysis - Report identifies needs in preventive healthcare

Marketing and Distribution - Mikro-Tip maker signs sales and marketing pact with ADInstruments

Mast Cell Function - Human mast cells have Toll-like receptor 4, innate and adaptive immune responses

Mediastinal Tumors - Surgical treatment for giant solid tumors of the mediastinum

Medicaid - Administration's drug-record proposal criticized

Medicaid - Oklahoma lawmakers hope proposed rate increases will improve healthcare access

Medicaid - Repayment terms could sink struggling hospitals

Medical Malpractice Insurance - Florida state officials say law should lower doctors' insurance 7%

Medical Malpractice Insurance - More than 3,400 West Virginia doctors haven't paid required fee

Medical Malpractice Liability - Doctors' group votes for cap on damages from state-run health plan patients

Medical Malpractice Liability - Maryland governor to propose limits on claims

Medical Malpractice Liability - Massachusetts drawing up plan lawsuit-limiting plan

Medical Malpractice Liability - West Virginia panel faces deadline on compensation

Medical Malpractice Liability - Wyoming doctors, lawmakers debate damage caps

Medicare - Conservative groups pledge support for bill with health savings accounts

Medicare - Specialty hospitals say proposed prescription drug bill would hurt them

Medicare - Wheelchair scam amounts to $167 million in fraudulent claims

Medication Safety - Website alerts consumers about mixing medications with herbal supplements

Memory - Enzyme may turn fleeting experience into lasting memory

Meningococcal Vaccine - Doses of meningococcal C-tetanus toxoid vaccine can be reduced

Menopause - Local estrogens relieve postmenopausal lower urinary tract dysfunction

Menopause - Raloxifene decreases new fractures in women with vertebral cracks at baseline

Menopause - Study helps explain relationship between weight gain and female hormones

Menopause - Weekly doses of ibandronate improve postmenopausal osteoporosis

Mental Health - Postpartum psychosis can be managed with standard therapy

Mental Health - RNA structure of trinucleotide repeats linked to human neurological diseases

Mental Health - Study finds new mothers are resistant to stress

Mental Healthcare - System is one of most overburdened of community resources

Mergers and Acquisitions - Amedisys continues expansion in Texas market

Mergers and Acquisitions - Huber Engineered Materials announces acquisition of Micro Powders and Braig

Mergers and Acquisitions - Iowa company to be acquired by Omni Medical

Mergers and Acquisitions - Medifast acquires Hi-Energy Weight Control Centers

Mergers and Acquisitions - Merger of drug delivery, biotech firms valued at $515M

Mergers and Acquisitions - Net Force signs letter of intent to acquire Chinese biotech company

Mergers and Acquisitions - Ophthalmology company completes purchase of manufacturing facility

Mergers and Acquisitions - Pharmaceutical company acquires exclusive North American rights to Azasan

Metabolic Syndrome - Elementary signs of heart disease found in children

Microarray - Fully customizable DNA array platform launched

Microbiology - A quick diagnosis of toxic shock syndrome is critical for avoiding mortality

Minority Health - University center to study chronic disease among American Indian elders

Mitral Valve Surgery - Chordal-sparing mitral valve replacement: pitfalls and techniques

Molecular Dynamics - IgG light chain differs in side chain mobility depending on electrostatics model

Mosquito-borne Disease - Genomics spawns novel approaches to mosquito control

Mosquito-borne Disease - Peritrophic matrix limits blood digestion rate in malaria-carrying mosquitos

Multiple Myeloma - MIP-1 alpha levels correlate with survival in multiple myeloma patients

Multiple Sclerosis - MS autoantigen myelin oligodendrocyte glycoprotein found in Schwann cells

Multiple Sclerosis - Molecular dynamics exposes alpha-helices in myelin basic protein

Multiple Sclerosis - Preclinical data shows promise for multiple sclerosis and spinal cord injury

Muscular Dystrophy - Blood cells could build muscle in neuromuscular diseases

Muscular Dystrophy Diseases - Muscular dystrophy of the calves after age 30 is distinct from Miyoshi myopathy

Mutagenesis - Thrombospondin 1 restoration by low-dose doxycycline may control angiogenesis

Myasthenia Gravis - New drug treats autoimmune disease that weakens eye and body muscles

Mycobacterium - Microfluidic labchip instrument used to identify Mycobacterium species

Myelodysplastic Syndrome - The role of erythropoietin in the anemia of myelodysplastic syndrome

Nerve Damage - Nerve prosthesis developed in Umea

Nerve Damage - Scientists use enzymes to enhance regeneration of damaged peripheral nerves

Nerve Regeneration - Following spinal cord injury, humans may produce nerve regenerators transiently

Network Expansion - Humana adds 20 HCA facilities in Georgia

Neurodegeneration - Loss of huntingtin disrupts axonal transport in Drosophila

Neuroimmunology - CD137, ligand are expressed in human neurons, astrocytes; upregulated by FGF-2

Neuroscience - Angiogenic protein encourages secondary damage after spinal cord injury

Neuroscience - Antisense knockdown of the p75 neurotrophin receptor delays motor neuron disease

Neuroscience - Booster genes may give a lift to the muscles of muscular dystrophy patients

Neuroscience - Breastfeeding may trip mother's "reward system," stimulating bonding with baby

Neuroscience - Clinical mass spectrometry in neuroscience proteomics reviewed

Neuroscience - Faulty dynamic cerebral autoregulation prevails in women with eclampsia

Neuroscience - Most women experience heightened chemical senses during pregnancy

Neuroscience - Neurexin-related protein terminates axonal branches in C. elegans

Neuroscience - Neurotransmitter release regulated by phosphorylation

Neuroscience - Neurotrophin family of neurotrophic factors regulates axonal growth

Neuroscience - Syntrophin gene of C. elegans related to dystrophin and dystrobrevin

Non-Hodgkin Lymphoma - Data release from phase III ECOG 4494 study of Rituxan

Nosocomial Infection - Pennsylvania now requires hospital-acquired infections to be reported

Nutritional Supplements - Biopharmaceutical company introduces six new nutritional health supplements

Obesity Surgery - Bariatric surgery affects plasma ghrelin level activity

Obesity Therapy - MCH-1 receptor modulation alters appetite, body weight, and adiposity

Obstetrics - Blood flow in the pregnant uterus is protected during moderate exercise

Obstetrics - Brachial artery flow-mediated dilation assessments predict pre-eclampsia

Obstetrics - Changing partners increases risk of preterm birth

Obstetrics - Fluoroscopically assisted treatment for hip fracture minimally exposes fetuses

Obstetrics - Insulin-like growth factor II foments vascular adaptation to pregnancy

Obstetrics - Intrafetal ablation is best for managing acardiac twins

Obstetrics - The corpus luteum vasculature of pregnancy does not undergo apoptosis

Obstetrics - U.K. agency urges gender selection ban

Obstetrics - Women feel unprepared for operative deliveries, study says

Occupational Exposure - Aromatic hydrocarbon-DNA adducts are higher in leukocytes of rickshaw drivers

Occupational Health - Acute occupational disinfectant-related illness among youth reported

Occupational Health - Healthcare workers experience a decline in blood and body fluid exposures

Ocular Diseases - NEI selects protein biochip system for the study of diseases of the eye

Ocular Infections - FDA accepts NDA for ophthalmic anti-inflammatory/antibiotic

Oncology - Enzyme upregulation in the T cells of mammary tumor bearers points to invasion

Oncology - Reactive oxygen species exacerbate the effects of hepatitis B virus X protein

Oncology - The angiostatic properties of STI-571 may be valuable therapy for many disorders

Oncology Trials - Clinical trials in pediatric cancer: Parental perspectives on informed consent

Ophthalmology - Groups warn against mobile eye clinics

Opportunistic Infection -  Mycobacterium xenopi treatment is unnecessary for HIV patients on HAART

Orthopedic Medicine - Hip arthroplasty is unlikely to cause obstetrical problems in young women

Osteoporosis - Estrogen stops experimental hyperthyroidism from reducing bone density

Osteoporosis - Habitual tea consumption has a minimal effect on fracture risk

Osteoporosis - Sheep are useful models for studying bone density

Osteoporosis - Vertebral deformity characteristics predict subsequent risk for bone fractures

Osteosarcoma - p53 mutations in osteosarcomas correlate with high levels of genomic instability

Ovarian Cancer - A phase II trial of bryostatin-I in recurrent epithelial ovarian carcinoma

Ovarian Cancer - Granulosa cell tumor of the ovary - Retrospective analysis of 45 cases

Ovarian Cancer - Liposomal doxorubicin and gemcitabine in the salvage treatment of ovarian cancer

Ovarian Cancer - Reproductive factors and epithelial ovarian cancer risk by histologic type

Oxycodone Abuse - New drug candidate being developed to deter oxycodone abuse

Pain Medicine - Antidepressants decrease chronic pain by inhibiting TNF production in brain

Pain Medicine - Environmental influences found to have role for development of adult pain system

Pain Medicine - Newly revealed cellular mechanisms underlie memories of pain

Pain Medicine - Patients with liver diseases report having upper abdominal pain symptoms

Pain Medicine - Postoperative pain after hysteroscopy and D and C is usually minimal

Pancreatic Cancer - BRAF and K-ras gene mutations in human pancreatic cancers

Parachlamydia Acanthamoeba - Free-living amoebic pathogen P. acanthamoeba replicates in macrophages

Parkinson Disease - IND application filed with FDA For AV201

Parkinson Disease - Implanted stimulator impairs cognitive function

Parkinson Disease - Several commonly used pesticides are toxic to mitochondria

Parkinson Disease - Study links bats to brain disease

Parkinson Disease Therapy - Levodopa therapy in Parkinson disease does upregulate serum IL-15 and RANTES

Patents - Court upholds stem-cell patents

Patents - Molecular Devices settles infringement suit

Patents - Patent expands adeno-associated virus manufacturing processes and technology

Patents - Stem cell expansion technology receives patent in Australia

Patents - Two patents granted for treatment of inflammatory diseases

Pediatric AIDS - Potential low-cost options for monitoring disease status described

Pediatric Depression - Bullied children at risk of depression, antisocial behavior

Pediatric Hypertension - Patient enrollment completed in Altace pediatric clinical trial

Pediatrics - Birthweight standards need to be locally and ethnically congruent

Personnel - Bill Arthur named president and COO of diabetes management company

Personnel - Blood products company adds Dr. Steven Gerber and Robert Chilton to team

Personnel - Bristow named general counsel at dermatology company

Personnel - Colorado-based device company announces organizational changes

Personnel - Corporate VP of global quality management named at pharmaceutical firm

Personnel - Diagnostic testing company promotes Paul Touhey

Personnel - Eric von Hofe named VP of technology development

Personnel - Immunotherapeutics company hires new VP

Personnel - Innovex appoints new head of U.S. operations: Anthony Yost

Personnel - James Olmstead, John Zurbach join HealthAmerica as vice presidents

Personnel - John Park to lead XCEL Healthcare and BioSelect Innovations divisions

Personnel - Kerry Segal named VP, business development at cellular immunotherapy company

Personnel - LivHOME appoints Martin Ramseck as senior vice president, sales and marketing

Personnel - Mark Evenstad assumes responsibilities of president and COO of lab company

Personnel - McCabe joins board of advisors at nanotechnology company

Personnel - Michael Hope becomes VP and is named to board of directors

Personnel - NeuroSource names new chairman of the board: Thomas W. Hodson

Personnel - Pharmaceutical company names Charles W. Cramb to board of directors

Personnel - Physicist, inventor named to board at bioinformatics firm

Personnel - Richmond to resume duties as interim CFO at drug delivery firm

Personnel - Schering-Plough appoints Robert Bertolini as chief financial officer

Personnel - Stent-coating company names Dr. Arun Chockalingam as a special advisor

Personnel - Taylor named chief operating officer at disease management firm

Personnel - Timothy P. Fitzgerald named CEO and president of therapeutic patch company

Personnel - Two new members added to board at drug delivery company

Personnel - VP treasury, financial operations named at oncology drug company

Personnel Appointments - State hospital authorized to hire new director

Personnel Appointments - Wyoming Medical Center names new CEO

Pertussis Therapy - Azithromycin is an effective treatment for pertussis

Phagemid System - Cre-mediated recombination efficiency determinable with immediate visual system

Pharmacokinetics - Narapril and Renitec are bioequivalent brands of enalapril

Pharmacy Benefits - MBI and Familymeds announce on-line pharmacy partnership

Pharmacy Benefits - Medica announces affordable drug benefit for Medicare beneficiaries

Pharmacy Technology - Huntington Hospital purchases Pharmacy IV automation technology

Phobias - Drug may help people unlearn fears

Phytotherapy -  Centella asiatica derivatives evoke genetic changes linked to wound repair

Phytotherapy - Saikosaponins from Bupleurum exhibit antiviral and anticancer properties

Pituitary Tumors - The Kruppel-like transcription factor 6 gene in sporadic pituitary tumors

Policy - AIDS epidemic should be treated as a disaster

Policy - Clinical use of embryonic stem cells jeopardized by Bush's funding

Policy - Open-access publishing: The debate continues

Policy - Physician organizations urge Secretary Thompson to defend NIH review process

Policy - UNAIDS welcomes Canada's move to implement WTO pact on generic medicines

Portosystemic Shunts - Survival in patients undergoing transjugular intrahepatic portosystemic shunt

Post-operative Pain - Clinical results released for pain medication using the Saber delivery system

Postinfluenza Seizures - Influenza A virus can cause encephalopathy after respiratory improvement

Premature Menopause - Half of premature menopause and ovarian failure patients still have follicles; can conceive

Preparedness - U.S. plans to grade states' bioterrorism plans

Prescription Drug Importation - Canada cracks down on drugs for Americans

Prescription Drug Importation - North Dakota officials eye prescription drugs from Canada

Prescription Drug Importation - Vermont continues Canadian drug access

Prion Disease - Treating dental patients with prion diseases discussed

Prion Protein Function - Copper, zinc are shuttled by prion protein from membrane to endosomes and Golgi

Probiotic Benefit -  Bifidobacterium DNA induces PBMC IL-10; reduces gut IL-1, increases IL-10

Prospective Health Modeling - I-trax selected by MedCost to forecast future health costs

Prostate Cancer - Functional results of various surgical techniques for radical prostatectomy

Prostate Cancer - Genetic mapping of allelic loss on chromosome 6q in prostate carcinoma

Prostate Cancer - Improving quality of life in men with prostate cancer

Prostate Cancer - Indications for and results of radical prostatectomy

Prostate Cancer - No association of germline alteration of MSR1 with prostate cancer risk

Prostate Cancer - Transrectal ultrasound-guided punch biopsies of the prostate

Protein Processing - Hepatitis C virus core protein assembles in the nucleus of yeast

Proteomics - 3D NMR spectrum of protein reconstructed from set of plane projections

Proteomics - Duro-pleural fistula diagnosed by beta2 -transferrin

Proteomics - Method to recognize single amino acid polymorphism in proteins developed

Proteomics - NMR allows high-throughput screening of structural proteomics targets

Proteomics - NMR of sensory domain of fumarate sensor DcuS of E. coli reported

Proteomics - Perlecan play role in skeletal development and diseases

Proteomics - Protein conformational dynamics probed by single-molecule electron transfer

Proteomics - Protein modifications determined by ion cyclotron resonance mass spectrometry

Proteomics - Semi-automated approach to protein NMR resonance assignments developed

Proteomics - Size exclusion chromatography used to measure protein-protein interactions

Proteomics - The osteopontin-derived peptide SVVYGLR encourages angiogenic activity

Proteomics - Thyroid stimulating hormone regulates VEGF from alternative tissues

Psoriasis - 10-year study leads researchers to psoriasis genes

Public Health - Blood center warns that increasing donor deferrals threatens blood supply

Pulmonary Cancer - Ultrasonographic localization of occult pulmonary nodules during VATS

Pulmonary Medicine - Caesarean delivery impacts younger infants with hyaline membrane disease

Pulmonary Medicine - Endostatin and vascular endothelial growth factor are imbalanced in emphysema

Pulmonary Medicine - Pulmonary surfactant protein SP-A interacts with DPPC/Egg-PG bilayers

RNA Research - Agreement signed for RNA interference studies

Radiation Therapy - Report from the SWOG Radiation Oncology Committee 2003

Rankings - Hearing aid manufacturer ranked among fastest-growing technology companies

Rectal Cancer - Endocavitary radiation therapy for rectal adenocarcinoma - 10-year results

Rectal Cancer - Rectal carcinoma in Egyptian patients less than 40 years of age

Recurrent Respiratory Papillomatosis - Data presented from phase II trial on recurrent respiratory papillomatosis

Regulatory Issues - WHO steps up action against fake medicines

Reimbursement - Medicare to cover annual InSure testing for colorectal cancer screening

Renal Cancer - Surgical treatment of pulmonary metastases from renal cancer

Renal Failure - Dietary calcium lowers plasma cholesterol and improves vascular tone in CRF patients

Renal Tumors - Molecular subclassification of renal tumors and discovery of diagnostic markers

Reproductive Medicine - Different views challenge how leucocyte quantity in semen should be defined

Reproductive Medicine - Fetal bone retained after pregnancy termination doesn't always alter fertility

Reproductive Medicine - Seminal oxidative stress is a plausible explanation for infertility

Reproductive Medicine - Seminal reactive oxygen species hamper fertilization and embryo development

Research Studies - Methods for comparing the results of different studies

Resuscitation Devices - Norwegian organizations contract with U.S. defibrillator service company

Retinal Imaging - HRT II offers new options for detecting retina conditions

Retinopathy - Measurements of ocular oxygen tension are expected to advance eye research

Rheumatoid Arthritis - Survey shows that Europeans underestimate the impact of rheumatoid arthritis

Rheumatology - Once-weekly clodronate prevents steroid-induced bone loss in arthritis patients

SARS - Canada lab to use monkeys for SARS research

SARS - Hospital officials say degenerative bone disorder found in 49 patients

Sarcoma - PET with fluorine-18-deoxyglucose in detecting recurrent and metastatic sarcoma

Scleroderma Diagnostics - Pulmonary fibrosis, hypertension may be due to anti-endothelial antibodies

Seasonal Affective Disorder - Light-treatment increases biopterin level in seasonal affective disorder (SAD)

Sex Hormones - Delayed neutrophil apoptosis occurs with female sex hormones, also increased ROI

Sexual Dysfunction - Study: Female sexual dysfunction drug market to grow 10% over next 5 years

Skin Cancer - New and emerging topical approaches for actinic keratoses reported

Skin Cancer - Nonmelanoma cancer associated with other cancers

Skin Infections - New antibiotic - Cubicin - shipped to U.S. institutions

Small Cell Lung Cancer - Inactivation of Trp53 and Rb1 in lung endothelial cells creates SCLC in mice

Squamous Cell Carcinoma - First commercially licensed gene therapy drug approved for production

Staffing - Hospitals develop incentives to attract and keep nurses

Staffing - Most newly hired nurses are over 50

Staffing - Nursing shortage eases in Georgia, but experts look ahead

Staphylococcal Enterotoxins - New staphylococcal enterotoxin SER may be related to SEG; found in 2 plasmids

State-Subsidized Healthcare - Audit shows Texas is owed millions from managed care contracts

State-Subsidized Healthcare - Changes in Connecticut plan becoming more costly

State-Subsidized Healthcare - Comptroller issues scathing report on TennCare appeals process

State-subsidized Healthcare - Utah's health plan for the poor goes to enrollment application

Stem Cells - Company receives U.S. patent for stem-cell culture medium

Stem-Cell Research - Bone marrow-derived cells offer little hope for repairing damaged livers

Stem-Cell Research - First analysis of hematopoietic stem cell proteome completed

Stem-Cell Research - Key components of hematopoietic stem cell niche identified

Stem-Cell Research - Lysophospholipids synergistically promote primitive hematopoietic cell chemotaxis

Stem-Cell Research - Osteoblastic cells regulate hematopoietic stem cell niche

Stem-Cell Research - Stat5 involved in hematopoietic commitment of embryonic stem cells

Stem-Cell Research - The power of adult stem cells can be harnessed for tissue repair

Stem-Cell Transplantation - Allogeneic RIST could be outpatient procedure

Stem-Cell Transplantation - CXCR4 antagonist mobilizes CD34+ cells

Stem-Cell Transplantation - Conditioning regimen strongly influences post-SCT IPS risk

Stem-Cell Transplantation - Data on AMD3100 to be presented at ASH

Stem-Cell Transplantation - Despite complete chimerism, post-BMT mesenchymal stem cells lack donor genotype

Stem-Cell Transplantation - Infliximab raises post-SCT risk of non-Candida invasive fungal infections

Stem-Cell Transplantation - Low CsA levels, methotrexate use linked to heightened aGVHD risk in children

Stem-Cell Transplantation - Natural killer cell chimerism may mark children with high graft rejection risk

Stem-Cell Transplantation - Post-PBSCT leukocyte and cytokine profiles determined

Stem-Cell Transplantation - Results of bone marrow and PBSC donation compared

Stock Offering - Maker of da Vinci Surgical System completes public offering

Streptococcus Pneumoniae - Brain ciliated ependyma appear to sustain damage during bacterial meningitis

Streptococcus Pneumoniae - Penicillin therapy for S. pneumoniae can create an inflammatory reaction

Streptococcus Pyogenes -  Streptococcus pyogenes HtsA, upregulated in blood, binds one heme molecule

Streptococcus Vaccine - CDCP recommends pneumococcal polysaccharide vaccine for adults older than 65

Stress - Caregivers of family members with dementia have more health problems than noncaregivers

Stress - Cognitive function declines during interracial interaction

Stress - Motherhood appears to induce protective cognitive responses

Stress - Research shows women crime victims fear crime less than men

Stress Urinary Incontinence - Data: SPARC Sling System is a safe and effective treatment for women

Stroke - Inflammation kills new brain cells

Subarachnoid Hemorrhage - High caseload hospitals show lower subarachnoid hemorrhage mortality rates

Substance Abuse - Rutgers awarded $6 million grant to develop innovative prevention programs

Substance Abuse - SAMSA: Many substance abusers "not ready" to seek treatment

Substance Abuse - School-based prevention program reduces smoking and alcohol use in children

Substance Abuse - Yerkes researchers discover natural brain chemical reduces effects of cocaine

Sudden Cardiac Death - Public-access defibrillator use increasing

Synthetic Human Secretin - Clinical trial initiated for subcutaneous dosage form of secretin

Systemic Lupus Erythematosus - Company reports results of phase I clinical trial of Lymphostat-B

Systemic Lupus Erythematosus - Heart risk tied to blood vessel cell death

T-Cell Anergy - Chronic exposure to antigen induces IFNgamma-dependent TCR downregulation

T-Cell Function - Intron 3 of TNF-alpha gene controls cytokine expression by specific cell types

T-Cell Homeostasis - All CD8+ T cells respond to IL-15 with expansion and cytotoxic function

T-Cell Maturation - IKK2 is necessary for development of regulatory, memory, peripheral T cells

Teen Pregnancy Risk - Folate, vitamin B-12, and iron can all be compromised in pregnant adolescents

Telemedicine - Memorial Sloan-Kettering signs with telemedicine company

Telemedicine - Motion Media forges alliance with telemedicine company

Telemedicine - USDA grant enables project expansion in rural Oklahoma

Television - Physicians to spread word on negative effects of TV, drug ads

Temporomandibular Disorders - Osteoprotegerin is lower in synovial fluid of patients with osteoarthritic TMJ

Tendon Vasculature - Endothelial cells can be visualized in tendons immunohistochemically with CD-31

Terminal Cancer - Effect of nebulized furosemide in terminally ill cancer patients with dyspnea

Thrombosis - Aspirin may not be strong enough to prevent clots in some heart patients

Thyroid Cancer - Antitumor compound to be tested in newly diagnosed cancer patients

Thyroid Tumor Diagnostics - Galectin-3 is expressed in higher amount only in papillary thyroid carcinomas

Tobacco Use - Low monoamine oxidase B in peripheral organs in smokers

Tolerance Induction - High ILT3, ILT4 expression characterizes dendritic cells that are tolerized

Tolerance Induction - Recognition of antigens on regulatory CD4+ T cells aid tolerance induction

Toxicology - Pesticide-specific analysis will show how pregnant women in California fare

Transfusion Medicine - Granulocyte transfusions effective against drug-resistant infection in neutropenic patient

Transplant Medicine - Crystalline particles seen in University of Wisconsin perfusion solution

Transplant Medicine - Eicosanoids could be used to control inflammation, allograft acceptance

Transplant Medicine - Key-hole surgery makes live-donor kidney donation safer

Transplantation - HCV recurrence reflects low sequence diversity after liver transplantation

Transplantation - Neither liver transplantation nor HCV contraindicate renal transplant

Transplantation - Transplantation society releases guide for immunosuppressive drug use

Transplantation - Where livers and kidneys are both needed liver transplants should be done first

Tuberculosis - IFN-gamma-inducible LRG-47 plays key role in anti-TB immune defense

Tuberculosis Diagnostics - Amplified ribosomal DNA restriction analysis useful for identifying M. tuberculosis

Tuberculosis Diagnostics - Fluorogenic assay enables rapid and accurate TB diagnosis

Tuberculosis Diagnostics - Modified luciferase reporter phages enable rapid detection of TB drug resistance

Tuberculosis Diagnostics - Molecular assay enables rapid, accurate detection of mutant mycobacterial katG

Tuberculosis Diagnostics - Molecular assay suitable for high-throughput mycobacterial identification

Tuberculosis Drug Resistance - Fully automated assay suitable for identifying pyrazinamide-resistant TB

Tuberculosis Epidemiology - Amplified-fragment length polymorphism typing can complement RFLP

Tuberculosis Immunology - MyD88 primes macrophages for IFN-gamma activation, but has limited role in TB defense

Tuberculosis Proteomics - Mycobacterial heat shock protein HSP16.3 characterized

Tuberculosis Risk Factor -  IL-12B UTR mutation does not affect TB risk

Tuberculous Meningitis - MRI useful for detecting asymptomatic spinal arachnoiditis in TBM patients

Tumor Hypoxia - Hypoxia-inducible transcription factors influence cell types differentially

Tumor Suppression - The quest for a tumor suppressor gene phenotype

Type 2 Diabetes - 21-Week program guarantees to get blood sugar within normal ranges

Type 2 Diabetes - Glycemic control monotherapy granted tentative approval by FDA

Type 2 Diabetes - Study demonstrates improved glucose control in study of patients

Type 2 Diabetes Pathogenesis - Adipocytokins, obesity, and type 2 diabetes development reviewed

UV Exposure - Enzymes for melanin production in Koreans increase for a week after UV exposure

Ultrasound Screening - The evolving role of ultrasound in obstetrics/gynecology practice

Ultraviolet Exposure - Polymorphisms in DNA repair genes may be linked to immunosuppression, cancer

Ultraviolet Irradiation - UVB, UVC irradiation damage is detectable with antiserum in histology or ELISA

Urinary Tract Abnormalities - Genetic disorders of human congenital anomalies of the kidney and urinary tract

Urology - Doctors lack the major facts about urinary incontinence in women

Urology - Duloxetine significantly reduces stress incontinence episodes

Urology - Some doctors take a more proactive approach to treating urinary incontinence

Vaccine Adjuvant - Natural antibodies and complement are endogenous adjuvants for vaccines

Vaccine Development - Methods for identification of bacterial vaccine candidates reviewed

Vaccine Safety - Bioterrorism vaccination is contraindicated in some drug-allergic patients

Vascular Disease - Company initiates multidose phase I clinical trial with GH9001

Vascular Medicine - Leg blood flow decreases during moderate exercise in healthy older women

Vector Development - Fusion gene products facilitate the study of enzyme-mediated gene therapy

Vectors and Zoonoses - Angiogenic proteins accumulate in the brains of patients with cerebral malaria

Venous Insufficiency - Duplex ultrasound evaluation of lower extremity venous insufficiency

Venous Thromboembolism - Epidemiology and management of venous thromboembolism in patients with cancer

Ventricular Tachycardia - Implantable cardioverter defibrillator receives FDA approval and CE marking

Vertebrobasilar Ischemic Stroke - Stents combined with clot-busting drugs effective in limiting stroke impact

Viral Genomics - Alternative translation schemes control hepatitis C ARFP/F/core +1 coding

Viral Proteomics - Hepatitis C envelope glycoprotein E2 requires heparan sulfate for cell binding

Virology - Sodium stibogluconate inhibits authentic hepatitis C virus replication

Vital Signs Monitoring - California center converts to Masimo SET oximetry

Von Willebrand Disease - Evolutionary link proposed between WARP and FACIT-like collagens

Weight Control - Appetite stimulation by exercise uncertain

Weight Loss - Almonds help dieters lose weight, according to study

Weight Loss - Glucerna weight loss shakes for people with diabetes wins award

Weight Loss - Low-starch, high-fat diets appear to work

Wellness Programs - Online poll shows only 9% of employees enroll in corporate wellness programs

West Nile Fever - Substantia nigra involved in West Nile virus-induced encephalitis

West Nile Virus - First human trial of West Nile vaccine to begin

West Nile Virus - West Nile virus assay detects more than 800 infected blood donations

Women's Health - Dietary folate can counteract effects of alcohol on chronic disease risk

Women's Health - Mastopathy occurs as result of diabetes

Yersinia Enterocolitica - Some Yersinia enterocolitica biotype 1A appear to have virulence factors

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