Susan Hasty, Publisher
Table of Contents . . . January 19th, 2004
Non-Subscriber - Summaries OnlyRelated Areas: Other Issues in Health and Medicine Week | Other Publications
Depression - Research reveals social isolation boosts teen girls' suicide thoughts
Acne - New drug application submitted for Actiza
Bone Health - Inhaled corticosteroids found safe
Botulinum Toxin - Electrophoresis method to evaluate botulinum toxin activity developed
Bovine Spongiform Encephalopathy - FDA issues statement on new measures against BSE
Bovine Spongiform Encephalopathy - FDA issues statement on rendered products derived from BSE cow in Washington
Brain Injury - Depression, other psychiatric illnesses common following brain injury
Brain Tumor - Matrix metalloproteinases are tumor-specific markers in glioma patients
Brain Tumors - Individualized chemotherapy appears promising for glioblastoma multiforme
Brain Tumors - White matter fiber tracking is important for neurosurgical planning
Breast Cancer - Breast cancer patients of lower socioeconomic status may have poorer survival
Breast Cancer - Declining estrogen receptor-beta expression defines progression of breast cancer
Acute Myeloid Leukemia - PCR analysis can aid Aspergillus niger endocarditis diagnosis in AML patients
Breast Cancer - Exercise may reduce disease risk
Breast Cancer - Hemoglobin level may be related to tumor hypoxia and treatment resistance
Breast Cancer - Her-2/neu gene amplification in familial breast cancer predicts worse outcome
Breast Cancer - Higher dietary fat intake is associated with an increased breast cancer risk
Breast Cancer - Major milestone achieved in molecular diagnostics oncology program
Breast Cancer - Novobiocin reverses breast cancer resistance protein BCRP/ABCG2
Breast Cancer - Research paves way for individualized treatment
Breast Cancer - Tamoxifen has no effect on p27 protein expression in endometrium
Breast Cancer - The TGFB1 L10P polymorphism is not associated with breast cancer risk
Breast Cancer - Tumor size is likely unrelated to risk of recurrent breast cancer
Addiction Medicine - Amphetamines and cocaine regulate dopamine transporter function
Breast Cancer Therapy - Tumor cell contamination of stem-cell apheresis products has little clinical effect
Breast Tumors - Segmentation of breast tumor in 3-D ultrasound can obtain tumor volume
Breastfeeding - Advocacy groups in Oklahoma propose legislation
Breastfeeding - Continuing to nurse while dealing with viral infection is okay
Burkitt Lymphoma - Epstein-Barr virus is necessary for the survival of Burkitt lymphomas
Business & Finance - Healthcare provider launches online renewal service
Business & Finance - Insurer announces new physician advisory committee
Business & Finance - Two Passaic, New Jersey, hospitals consolidate
CNS Disease - Extracellular phospholipase A2 inhibitors can inhibit inflammation in CNS
Cancer - Phase III study for kidney cancer vaccine analyzed
Addiction Medicine - Bilirubin is a simple marker for alcoholic hepatitis treatment response
Cancer - Results from new cancer therapeutic published
Cancer Incidence - Parental exposure to the atomic bomb has not increased cancer in offspring
Cancer Mortality - Researchers report cancer incidence and mortality in the Netherlands
Cancer Prevention - College receives $10 million for cancer prevention trials
Cancer Prevention - National survey finds U.S. public enthusiastic about cancer screening
Cancer Risk - Cancer risks attributable to low doses of ionizing radiation reviewed
Cancer Therapy - Data presented on treatment to combat effects of chemotherapy
Cancer Therapy - Rho pathway inhibition produces glioma radiosensitization and oxygenation
Carcinogenesis - The major polyphenol from green tea may contribute to preventing carcinogenesis
Cardiac Rhythm Disorders - Alliance formed to offer broad electrophysiology solutions
Addiction Medicine - TWEAK identifies where intervention for alcohol use during pregnancy is needed
Cardiac Surgery - Company announces blood substitute studies for cardiac surgery
Cardiology - Biotech begins new Phase I study of cardiovascular drug
Cardiology - Cells with endothelial phenotypes have diverse origins
Cardiology - HDL therapy receiving heightened interest
Cardiology - Hypoxia-inducible factor 1 regulates several factors to control angiogenesis
Cardiology - Invasive measures of pulmonary artery pressure complement Doppler assays
Cardiology - New agreement signed for cardiac safety information services
Cardiovascular Disease - MTHFR mutation significantly raises hyperhomocysteinemia risk in children
Cardiovascular Disease - Biopharmaceutical company acquired to develop cardiovascular disease treatments
Cardiovascular Disease - Changes in skeletal muscle gene expression during CHF elucidated
Adenocarcinoma - Lung adenocarcinoma may be associated with atypical adenomatous hyperplasia
Cardiovascular Disease - Distribution of the NPY 1128C allele determined
Cardiovascular Disease - Genetic and environmental risk factors for extremely high cholesterol levels identified
Cardiovascular Disease - Losartan may reduce risk of platelet-induced pulmonary thromboembolism
Cardiovascular Disease - Novel transthyretin mutation linked to heart failure
Cardiovascular Disease - Paraoxonase gene cluster mutations can predict heart disease risk
Cardiovascular Disease - Protein kinase C changes RKIP target from Raf-1 to GRK-2
Cardiovascular Disease - Selenium may protect against heart attacks in men
Cardiovascular Disease - Study shows multivitamin offers cardiovascular risk factor protection
Cardiovascular Disease Therapy - Current and future antiarrhythmic treatment reviewed
Cardiovascular Disease Therapy - Prevention of SR alterations may underlie beneficial effects of heart failure treatments
Aesthetic Surgery - Cosmetic foot surgery to beautify feet has serious risks
Cardiovascular Disease Therapy - Suppression of cardiomyocyte apoptosis has little effect on efficacy of MI treatments
Cardiovascular Risk - Trial studies best ways to prevent heart problems in type 2 diabetes patients
Cartilage Repair - Fibrin-chondrocyte constructs can be used to perform cartilage repair
Cataracts - Zinc may play role in development of diabetic senile cataractous lenses
Catheter Insertion - Peritoneal dialysis catheters can be inserted via a peritoneoscope
Celiac Disease - Knowledge of gluten-processing path should help celiac disease therapy emerge
Cell Biology - A big surprise: Young nerve cells can rewind their developmental clocks
Cell Biology - Endothelial cell-specific response characterizes VEGF receptor stimulation
Cell Biology - Method could detect protein-binding events, without fluorescent labeling
Cell Biology - Nitric oxide modifies how low oxygen levels impact cell physiology
Aging - Pneumonia-caused cellular immunity damage is reversible
Cell Biology - Transcriptome and glycome regulation prepare endothelial cells for death
Cell Counting - An SAP staining procedure is equal or better than IF for HbF cell counting
Cell Death - Endoplasmic reticulum pathways contribute to apoptosis
Cellular Senescence - Cellular senescence may be a trustworthy tumor suppressor mechanism
Central Nervous System - Ap-1 targets in the brain reviewed
Charcot-Marie-Tooth Syndrome - Late onset Charcot-Marie-Tooth 2 syndrome caused by mutations in MPZ gene
Chemokine Receptors - The E3 ubiquitin ligase AIP4, Hirs, and Vps4 coordinate CXCR4 ubiquitination
Chemotherapy - Cellular pH regulators may be promising molecular targets for chemotherapy
Childhood Obesity - Nutritive factors influencing development of childhood obesity outlined
Childhood Obesity - Obesity in 3- to 7-year-old New Zealand children is serious concern
Agriculture - Federal court trumps local township restrictions on use of biosolids
Chlamydia - Delay in cell death may lower Chlamydia infection but increase pathology
Chronic Berylliosis - Beryllium is detected lung tissue using electron probe X-ray microanalysis
Chronic Hepatitis C - Hepatic reserve marks survival in those with HCV-related liver cancer
Chronic Hepatitis C - Sepsis heightens mortality after retransplantation for recurrent HCV infection
Chronic Pancreatitis - Bilateral thoracoscopic splanchnicectomy most effective surgery for pancreatitis
Chronic Pancreatitis - Pylorus-preserving pancreaticoduodenectomy is effective but not superior
Class Switch Recombination - Class switch recombination has unique DNA recognition structures for enzymes
Clinical Trials - New central lab business created
Clinical Trials - Update released on investigational device exemption for drug stent
Cocaine Testing - An anti-BZE coated sensor can detect residual cocaine vapor plumes in the air
Allergic Rhinitis - Pranlukast reduces levels of cytokines, eosinophils in rhinitis nasal mucosa
Cochlear Implants - Software tool can analyze multichannel cochlear implant signals
Collaborations - Agreement signed with Mitsubishi for irritable bowel syndrome compound
Collaborations - Alliance pledges to serve people with alpha-1 antitrypsin deficiency
Collaborations - Antibody deal with Amgen restructured
Collaborations - Biotech software company announces deal to distribute database
Collaborations - Cardiac safety monitoring, information distribution services deal signed
Collaborations - Cornerstone signs exclusive agreement with Amerinet
Collaborations - Deal signed for development of sustained release generic product
Collaborations - Deal with Johnson & Johnson expanded to include obesity
Collaborations - Intellectual property for antibodies binding to IL-12 licensed
Pediatrics - U.S. CDC releases annual summary of pediatric vital statistics for 2002
Allergy - Survey shows more allergy sufferers seek medical attention for symptom relief
Collaborations - License, supply agreement signed for osteoarthritis product
Collaborations - Marketing, communications contract extended with ChainDrugStore.net
Collaborations - Purchasing agreement signed for electrophysiology systems
Collaborations - Rights assigned from complement research to pharmaceutical company
Collaborations - VaxImmune vaccine adjuvant licensed to Chiron
Colon Cancer - Colorectal tumors are not caused by germline deletions of EXO1
Colon Cancer - Phenethylisothiocyanate induces GADD gene activation in colon cancer cells
Colon Cancer - Positive ursodiol disulfate study results reported
Colon Cancer Screening - Gastrointestinal specialists comment on new study on "virtual" colonoscopy
Colorectal Adenomas - Cigarette smoking and colorectal adenomas are associated
Allergy Medicine - Allergy to goat, sheep milk, but not cow, is due to greater casein homology
Colorectal Cancer - Four-drug regimen is feasible in advanced colorectal cancer
Colorectal Cancer - Study to evaluate photodynamic therapy for liver metastases from colorectal cancer
Complementary and Alternative Medicine - Green tea reduces body fat accretion caused by high-fat diet in rats
Complementary and Alternative Medicine - Licorice extract may stop cancer
Complementary and Alternative Medicine - Swaziland: AIDS toll leads to flood of bogus "miracle" cures
Complementary and Alternative Medicine - U.S. bans ephedra, drug linked to deaths
Conferences - Company announces participation in healthcare conference
Congestive Heart Failure - Encouraging signs follow muscle cell transplantation into damaged hearts
Coronary Artery Bypass - Coronary artery bypass graft patients have higher plasma, surface CD163 levels
Coronary Artery Bypass - Modified ultrafiltration benefits dialysis patients undergoing CABG
Allergy Medicine - Childhood allergies can be induced by the environment early in development
Coronary Artery Bypass - Study: Coronary bypass on beating heart results in more failed grafts
Coronary Artery Disease - European phase II trial of Hemopure initiated in angioplasty patients
Coronary Artery Disease - FDA panel underscores need for greater understanding of aspirin's benefit
Coronary Artery Disease - Utility of myocardial perfusion imaging for analysis of CAD patients reviewed
Corporate Update - Biotech company announces 2004 strategic initiatives
Corporate Update - Pronova Biocare sale announced
Correctional Health - Report says Ohio needs to improve inmate healthcare
Cough - Chronic cough is due to abnormal release of inflammatory mediators within the airway
Cowden Syndrome - Human Lhermitte-Duclos disease may be caused by mutation, dysfunction in PTEN
Cranial Lesions - Stereotactic radiosurgery is a viable option for performing neurosurgery
Allergy Medicine - Electrotransfer of interleukin-10 prevents bronchopulmonary hyperreactivity
Creutzfeldt Jakob Disease - "Human" mad cow usually not tied to diet
Creutzfeldt-Jakob Disease - In cerebellum of Creutzfeldt-Jakob patients, nestin increases with severity
Creutzfeldt-Jakob Disease - U.S. quarantines calves from diseased cow
Critical Care Medicine - Respirator weaning with adaptive support ventilation effective after heart surgery
Crystallography - Complement protein C1q has a trimeric, spherical shape that may aid binding
Cystic Fibrosis - The A561E cystic fibrosis mutation is a class II, protein trafficking defect
Cystitis - Pharmaceutical company receives second milestone payment for launch of Uracyst-S
Cytotoxic Drug Contamination - Low-level cytotoxic drug contamination found on the outside of drug vials
DNA Vaccine - Plasmid DNA activates dendritic cells via toll-like receptor 9
Deep Vein Thrombosis - Study finds 1% of air travelers develop injurious blood clots
Allergy Medicine - Five IgE epitopes in chicken egg ovalbumin cause allergy
Dendritic Cell Function - Cyclosporine may induce tolerogenesis by reducing dendritic cell IL-2, IL-12
Dental Healthcare - Kansas program to offer low-cost dentistry services in 3-year project
Depression - Depression may be linked to proinflammatory cytokine-serotonin interaction
Depression - Psychiatrist awarded grant to study effects of parental suicide
Depression - Study: Depression doesn't affect Chicanos
Dermatology - Vascular changes signal squamous cell carcinoma progression
Dermatology - Verapamil inhibits interleukin-6 and angiogenic growth factor in fibroblasts
Developmental Biology - New roles for protein modifications in cell migration
Developmental Biology - Sticky uterine coating helps embryo implant in uterus
Allergy Medicine - Gluten intolerance no longer considered rare
Diabetes - Magnesium may reduce risk for type 2 diabetes
Diabetes - Weight loss drug may reduce threat of type 2 diabetes
Diabetes Complications - Methods for preventing complications of diabetes reviewed
Diabetes Genetics - Researchers identify gene that causes insulin resistance in Mexican Americans
Diabetes Genomics & Genetics - Genetic predisposition to obesity and type 2 diabetes linked
Diabetes Pathogenesis - Beta cell death triggers priming of self-reactive T cells by dendritic cells
Diabetes Pathogenesis - Muscle-specific Pparg deletion causes insulin resistance
Diabetes Prevention - Diet high in magnesium lowers diabetes risk
Diabetes Risk Factor - No link found between preeclampsia or cesarean section and type 1 diabetes
Diabetic Retinopathy - Drugs capable of controlling angiotensin II may halt diabetic eye disease
Allergy Medicine - Job syndrome can be relieved by long-term oral penicillin treatment
Diagnostics - FDA approves molecular diagnostic test for sexually transmitted diseases
Diagnostics - TaqMan PCR suitable for quantification of EBV DNA in blood
Diet and Nutrition - Phenol levels and antioxidant activity measured in Turkish food
Disease Management - Study offers new findings on disease management effectiveness
Disease Prevention - Female OB/GYNs name obesity the greatest threat to women's health
Disease Tracking - New system provides disease and pathogen detection in food
Drug Abuse - Survey shows decline in teen drug abuse over past 2 years
Drug Delivery - "Smart bomb" destroys tumors in mice
Drug Delivery - Screening can identify chemicals that improve effectiveness of skin patches
Drug Development - Furamidine aza-analogues show promise as antiprotozoal agents
Allergy Medicine - Prevention of allergies by antigen avoidance may not always prove beneficial
Drug Development - New antibody collaboration announced
Drug Development - Nitric oxide donor-metronidazole hybrids have potent anti-H. pylori activity
Drug Development - Numbers of fish used in acute ecotoxicity testing of pharmaceuticals reduced
Drug Research - The norligan cis-Hinokiresinol curtails angiogenic response
Drug Resistance - Adefovir dipivoxil elicits a response in HBV-positive liver graft recipients
Drug Resistance - FLICE inhibitory protein supports chemoresistance in cervical cancer
Drug Resistance Reversal - Understanding drug resistance reversal may be complex and multifactorial
Embryonic Research - Slit3 protein involved in heart, kidney and diaphragm development
Employer-Sponsored Health Insurance - City workers in Gillette, Wyoming, unhappy with change in benefits
Employer-Sponsored Health Insurance - New Hampshire law changes health insurance rules for small-businesses
Allergy Medicine - Research suggests inverse relationship between rheumatoid arthritis and rhinitis
Employer-Sponsored Health Insurance - Plan to improve health insurance coverage stymied
Encopresis - Researcher finds that Internet-based treatment of childhood problem is effective
End-of-Life Care - Family members say dying patients need better emotional, medical support
Endocrinology - Ectopic ghrelin expression enhances growth
Endocrinology - Gravitational load modulates mammary metabolic function
Endocrinology - Hypoxia causes pituitary adenoma cells to stimulate new vessel growth
Endocrinology - Progesterone metabolite levels rise in women with chronic fatigue syndrome
Endocrinology - Skin temperature reflects changes brought on by hormones
Endometriosis - Nasal leuprolide product could offer noninvasive treatment for endometriosis
Enterobacter Sakazakii - Environmental presence of pathogen dangerous to infants is widespread
Alzheimer Disease - Abeta(1-42) can oligomerize into neurotoxins; Ginkgo extract inhibits it
Environmental Exposure - Atrazine contamination in water can be detected with a sensitive immunoassay
Environmental Health - Rice strains genetically engineered for mercury resistance may clean water
Environmental Toxins - Changes needed to reduce migrant farm worker exposure to pesticides
Enzymology - Calcineurin anchoring and cell signaling reviewed
Enzymology - Extracellular matrix signals collaborate to govern angiogenesis
Enzymology - Lipoxygenase makes transgenic tobacco less vulnerable to parasitic infection
Epilepsy - Companies enter broad agreement covering topiramate
Escherichia Coli - Latex agglutination, EIA are comparable tests for shiga toxin-E. coli
Esophageal Cancer - Aspirin trial launched to block heartburn's switch to cancer
Esophageal Candidiasis - EMEA marketing application filed for anidulafungin
Ethics - Study examines issues related to research involving prisoners
Alzheimer Disease - Cerebrospinal fluid markers function as predictors of Alzheimer disease
Exercise - Physical activity reduces depression in former elite athletes
Facilities - Maryland designated its first accredited chest pain center
Familial Cancer Risk - Familial risk of cancer is calculated
Fatty Acids - Omega-3 fats benefit people of many ages and health conditions
Fetal Medicine - Early recognition and treatment of fetal alcohol syndrome improves outcomes
Fetal Medicine - Infection prophylaxis improves odds after a prolapsed chorioamniotic membrane
Finance - Acquisition of cancer information registry business completed
Finance - Benefits management firm raises $8.6M
Finance - Biopharmaceutical company completes stock redemption; files shelf registration
Alzheimer Disease - HSPG2 A, APOE epsilon 4 alleles combined increase risk for Alzheimer disease
Finance - Cardiology company announces sale of Paulson stock
Finance - Cardiology company completes $3.1M private placement
Finance - Coventry Health Care announces three-for-two stock split
Finance - Credit facility renegotiated for health information company
Finance - DNA expression technology company to trade on Berlin Stock Exchange
Finance - Health technology and software company approves stock split
Finance - Home healthcare company revises quarterly outlook
Finance - Imaging company issues financial guidance for first quarter
Finance - Medical device company closes $12 million series B financing
Finance - Medical device company secures $2.2 million in financing
Alzheimer Disease - Imaging study pinpoints brain's myelin insulation as a key to AD
Finance - Medical device manufacturer announce closing of $12M total financing
Finance - Medical technology company to sell 3D visualization business
Finance - New registration statement filed for initial public offering
Finance - Pharmaceutical company announces change to earnings guidance
Finance - Pharmaceutical company announces exercise of over-allotment option
Finance - Pharmaceutical company announces year-end results
Finance - Pharmaceutical company completes $35M private placement
Finance - Pharmaceutical company files universal shelf registration statement
Finance - Shelf registration filed with SEC
Finance - Small protein company raises $1.2 million
Alzheimer Disease - In vivo reduction of amyloid-beta promoted by mutant copper transporter
Finance - Spinal access company announces research coverage by financial research group
Finance - Supply chain company pays off remaining debt
Finance - Taste receptor research company expands financing
Finance - Ultrasound systems manufacturer secures $25.6M in venture financing
Fitness - Full-bodied models highlight fitness ads
Fitness - Increased physical activity called priority for Americas
Fitness - Keeping resolutions for the new year
Food Allergy - Brownie mix recalled for pecan content
Food Supplements - NMR used to quantify ephedrine analogues from Ephedra species
Food Supply Safety - FDA and CBP announce their transitional compliance policy on food imports
Alzheimer Disease - Mayo Clinic receives $10 million gift to accelerate research
Food-borne Illness - Major cause of painful gastroenteritis under study at the Medical College of Georgia
Funding - 50 Washington, DC-area nonprofits receive health impact grants
Funding - Council would strengthen European research
Funding - Public-private collaboration to target new treatments for depression, nicotine addiction
Fungal Infection - Mycosis fungoides has changes in T-cell chemokine receptors that depend on stage
Fungal Infection - Severe alveolar echinococcosis can be controlled for years with benzimidazoles
GI Perforation - Radiologic approaches to diagnosing a variety of gastrointestinal perforations
Gastric Cancer - Cyclooxygenase-2 contributes to gastric carcinogenesis
Gastric Ulcer - Receptors play role in vascular effects of adrenomedullin in gastric ulcers
Gastroenterology - Carbon monoxide combines with nitric oxide to protect liver cells
Alzheimer Disease - No link found between TrkA polymorphisms and Alzheimer disease in Japanese
Gastroenterology - Estradiol treatment improves the healing of gastric and colonic injuries
Gastroenterology - Glucagon-like peptide-2 is not the only enterotrophin
Gene Expression - Companies renew commitment to gene expression tool
Gene Expression - Researchers describe a global toolkit for testing gene function
Gene Mutations - Polish families with ovarian and stomach cancer often have BRCA2 mutations
Gene Regulation - Non-small cell lung cancer cells are ideal targets for p53 gene transfer
Gene Suppression - Extended peptide nucleic acid conjugates have a greater capacity to bind DNA
Gene Therapy - Therapy containing hepatocyte growth factor gene improves hearing in rats
Gene Transfer - DNA encapsulation within polymeric sponges improves transfer efficiency
General Health - Survey shows flu tops germ concerns for 2004
Ambulatory Care - National standards sought for ambulatory care performance
Generic Drugs - Litigation status updated; FDA approves generic metolazone
Genetic Disorder - Familial Mediterranean fever with amyloidosis linked to mutation of MEFV gene
Genetic Disorder - Kinesin KIF21A mutations linked to congenital fibrosis
Genetic Disorder - Mutations in polyglutamine binding protein 1 gene cause mental retardation
Genetic Disorder - PANK2 mutations confirm HARP and Hallervorden-Spatz syndromes are allelic
Genetic Engineering - Reengineered dendritic cells readies cytotoxic T cells for select epitopes
Genital Herpes - Antibodies to HSV-2 glycoprotein G are not always there during primary infection
Genital Herpes - Researchers: Pill stops spread of herpes
Genomics - License for patented gene targeting technology granted
Genomics and Genetics - Mutations affecting lipoprotein phenotype in South European FH patients identified
Amycolatopsis - Cinnamaldehyde derivative inhibits nicotinoprotein alcohol dehydrogenase
Genomics and Genetics - Oxidative DNA damage underlies mitochondrial effects of cancer, HIV drugs
Geriatrics - Alliance to offer elder care program
Germ Cell Tumors - Infertility rates are low after chemotherapy for germ cell tumors
Glioma - P-glycoprotein mediates multidrug resistance in malignant glioma cell lines
Glucose Metabolism - Metabolism of D-glucose anomers in pancreatic islets reviewed
Gonorrhea - Louisiana has worst gonorrhea rate, in top 10 in two other STDs
Gout - New drug application submitted for Oxyprim
Gynecology - Adenovirus-mediated suicide gene therapy destroys ovarian cancer cells
Gynecology - Transvaginal ultrasound aids the diagnosis and treatment of urological disorder
Gynecology - VEGF-Trap is a potent ascites suppressor in ovarian cancer models
Amyloidosis - C-terminal of beta 2-microglobulin plays role in amyloid fibril formation
HIV Diagnosis - FDA OKs U.S. sale of 10-minute HIV test
HIV Epidemiology - Name-based reporting leads to better information in New York City
HIV Progression - Having a stable partner delays AIDS in HIV patients
HIV Testing - Uni-Gold Recombigen HIV test receives FDA approval
HIV Therapy - Best treatment for new HIV patients to be studied
HIV/AIDS - Infection with multiple HIV strains hastens disease progression
HIV/AIDS - Substantia nigra lesion-induced parkinsonism can mark AIDS onset
HIV/AIDS Cancer - Epidemiology of Kaposi sarcoma in Israel elucidated
HIV/AIDS Cancer - HAART improves outcome of HIV-related non-Hodgkin lymphoma
HIV/AIDS Coinfection - HIV coinfection does not alter efficacy of hepatitis C treatment
Amyotrophic Lateral Sclerosis - ALS disease stage related to changes in tau protein and S100 beta
HIV/AIDS Epidemiology - HIV-1 seroprevalence rates in women and relinquishment of infants to the state in Russia
HIV/AIDS Obstetrics - HIV testing acceptable to pregnant women and their husbands in India
HIV/AIDS Opportunistic Infection - Molecular blood test detects Penicillium marneffei
HIV/AIDS Opportunistic Infection - Pathogenesis and treatment of candidiasis-associated HLH reviewed
HIV/AIDS Opportunistic Infection - Solid phase cytometry test provides rapid Aspergillus fumigatus detection
HIV/AIDS Pathogenesis - Immune response to SIV infection in African green monkeys investigated
HIV/AIDS Proteomics - HIV Tat interacts with Notch protein EGF-like repeats and the EGF precursor
HIV/AIDS Proteomics - HIV Vif induces G2 /M arrest in feline and bovine cells
HIV/AIDS Proteomics - Mechanisms of HIV Vif-induced APOBEC3G degradation identified
Infertility - Men and women in infertile unions benefit from psychosocial intervention
Anesthetics - Protein kinase C plays role in action of volatile anesthetics
HIV/AIDS RNA Research - Homology requirements for optimal antiretroviral shRNA activity clarified
HIV/AIDS Therapy - Distal mutation cooperation needed for HIV multiprotease inhibitor resistance
HIV/AIDS Therapy - High viremia at start of triple-drug ART linked to increased mortality risk
HIV/AIDS Therapy - LC-MS method for measuring zidovudine and lamivudine in mice developed
HIV/AIDS Therapy - Levels of anti-p24 IgG1 may mark HAART efficacy
HIV/AIDS Therapy - Thymidine analogue mutation patterns identified
HIV/AIDS Tuberculosis - Rifampicin does not affect enfuvirtide pharmacokinetics
HIV/AIDS Vaccine - Antigen engineering promotes induction of HIV-neutralizing antibodies
Aneurysm - Neuroform stent shows good results for cerebral aneurysms
HIV/AIDS Vaccine - Candidate HIV-1 subtype C DNA vaccine for South Africa characterized
Haplotypes - Close look at gene shuffling spots copying
Head Trauma - Low-dose radiation in infancy may affect intellect
Health News - WebMD Health releases their top ten health stories of 2003
Health Statistics - Teen birthrate drops 7% in Arkansas
Healthcare Access - Church project would establish clinic and free medical care
Healthcare Access - Cut in Colorado medical fund has immigrant advocates concerned
Healthcare Access - New foundation supports healthcare for residents of Indiana
Healthcare Benefits - Study finds working Oklahomans uninsured
Healthcare Economics - Study tallies high costs of health-related lost work productivity
Aneurysm - Nonsurgical treatment may be most beneficial for older adults
Healthcare Economics - Vanderbilt study explores new ways to cut costs
Healthcare Economics - Working-age minorities face greater prescription drug affordability problems
Healthcare Information - Low-income Internet users in California benefit from online medical searches
Healthcare Insurance - BENU Washington expands products and access
Healthcare Reform - Maine's universal health plan takes shape
Hearing - New strategic plan in place for communications service provider for the deaf
Heart Attack Risk Factor - Platelet reactivity increased in patients with diabetes
Heart Disease - Primary endpoints met in phase I/II clinical trial of DX-88
Heart Disease Risk Factor - Time from diabetes diagnosis to therapy related to carotid artery thickness
Heart Failure - Triage B-type natriuretic peptide test approved for use on Beckman Coulter platforms
Angina - U.S. Food and Drug Administration advisory committee evaluates Ranexa
Heart Surgery - Proton magnetic resonance spectroscopy useful for pediatric brain imaging
Heart Transplantation - Questions about the safety and efficacy of cardiac gene therapy persist
Hematology - Elevated cobalamin levels may indicate severe liver disease
Hematology - Gene regulation could modify autosomal-dominant giant platelet syndromes
Hematology - Thrombin interaction with platelet membrane glycoprotein Ib alpha discussed
Hematology - Vectors encoding the heavy and light chains of FVIII correct hemophilia A
Hematology/Oncology - Effect of aging on hematopoietic system reviewed
Hemophagocytic Lymphohistiocytosis - Familial hemophagocytic lymphohistiocytosis has mutated hMunc13-4
Hepatitis B Vaccine - Immunity persists 4 years after hepatitis B vaccination
Hepatitis B Virus - Rates on the decline in the United States but not among adults
Angiology - Elastin induces myofibrillogenesis via VGVAPG domain
Hepatitis B Virus - Study will compare two antivirals for lamivudine-resistant disease
Hepatitis C Virus - Persistently abnormal liver function tests: Marker of liver disease?
Hepatitis Virus - Antiseptic hand spray formula proven to kill hepatitis A, B and C viruses
Hepatocellular Carcinoma - A novel lipophilic platinum complex is effective in treating HCC
Hepatocellular Carcinoma - Gemcitabine is equivalent to other cytotoxic agents when used alone for HCC
Hepatocellular Carcinoma - Growth of hepatocellular carcinoma cells is arrested by troglitazone
Herpes Simplex Virus - Myeloid, not hepatic, C3 controls effectiveness of antibody response to HSV
Hormone Replacement Therapy - Compound discovered that lacks estrogen's risks
Hormone Replacement Therapy - FDA teams up with women's health organizations to raise awareness about HRT
Hormone Replacement Therapy - Study results have altered how physicians prescribe, women use HRT
Animal Models - Heart and eye disorders in murine MPS IV model identified
Huntington Disease - Could a protein have saved Salem's witches from burning at the stake?
Hypertension - High blood pressure may cause increased sE-selectin, sVCAM-1 in serum
Hypertension - Remodulin receives preliminary notice of approval in Switzerland and Australia
Hypertension - Two milestones achieved in the development of DNA-based diagnostic tests
Hypertension - Use of drug declined following release of trial results
Hypertension Therapy - Effects of apomorphine in hypertensive rats clarified
Hypertension Therapy - Lipid-lowering drugs have limited efficacy in Japanese hypertensives
Hypertension Therapy - Pharmacokinetics of irbesartan examined in aortic coarctated rats
Hypoparathyroidism - Researchers discuss the diagnosis and treatment of iatrogenic hypoparathyroidism
Hypothalamic Tumors - Researchers describe tanycytomas, a newly characterized tumors
Anopheles - Synergy of insecticide applied to mosquito nets described
Hypothalamus - Chromatin-derived acidic peptide exert effects in hypothalamus
Hysterectomy - Nerve-sparing radical hysterectomy is promising in preserving bladder function
Imaging - Ultrasound allows better visualization of hyperthermia technique
Immune System Function - Study of the unique mechanisms in ocular immune privilege may help other areas
Immunology - Heat shock protein 70 gene therapy and hyperthermia boost antitumor immunity
Immunology - Leptin has differential effects on monocyte ROS activity during HIV infection
Immunology - Natural killer cell functions mediated by neuropeptide substance P
Immunology - New label-free immunosensor for proteins is based on imaging ellipsometry
Immunology - Phagocytosis accelerates maturation of polymorphonuclear leukocytes
Immunology - Phase I trials initiated for a compound to combat several inflammatory conditions
Anthrax - Anthrax mounts nuclear attack on glucocorticoid signaling
Immunology - Protein makes LIGHT of cancer
Immunology - Regulatory T cells play a role in hepatitis C virus persistence
Immunology Research - $1 Million gift helps establish immunology center
Infection - Sale of ocular infection drug completed
Infection Control - Rubbing hands with antiseptic may help prevent nosocomial urinary tract infections
Infectious Disease - Immunologic features during different stages of Chagas disease characterized
Inflammatory Bowel Diseases - Bowel disease complications can affect the eye; problem can be better managed
Influenza - BCBSNC gives North Carolina Health Departments $300,000 for flu vaccines
Influenza - Flu outbreak tests new federal law limiting release of medical information
Influenza - Flu treatment options offered
Anthrax - Calcium may play role in folding pathway of anthrax protective antigen
Influenza - Influenza virus envelope cholesterol is required for virus entry, infectivity
Influenza - Nasal spray flu vaccine may help prevent influenza in healthy children
Influenza - Officials hope break brings flu downturn
Influenza - Sales of thermometers up 20% due to flu epidemic
Influenza Vaccine - Aggregate content influences Thl/Th2 response to influenza vaccine
Information Technology - ER information system selected by California healthcare provider
Information Technology - Maine health alliance to uses telemedicine to share data
Information Technology - New partnership helps with HIPAA compliance
Information Technology - Orthopedic outcomes software provided to Minnesota Clinic
Information Technology - Physicians use the Internet to remotely monitor heart failure patients
Anthrax - FDA clears lab culture test for anthrax
Information Technology - Smokers get cutting edge technology to help kick the habit
Inhaled Insulin - Human trials of Alveair insulin pulmonary technology about to begin
International Health - Paternal status affects pediatric mortality in Mozambique
Jaundice - Chinese herbal preparation speeds clearance of bilirubin
Kidney Transplant - Antibody-mediated kidney rejection can now be diagnosed, may soon be treatable
Klebsiella - Klebsiella oxytoca harbors carbapenem-hydrolyzing beta-lactamase KPC-2
Lactation - Several factors determine whether urban women elect to breastfeed or not
Laparoscopic Ureteral Injury - Researchers review laparoscopic ureteral injury occurring during pelvic surgery
Leg Ulcers - Premarket approval application to be filed for venous leg ulcer treatment
Legal Issues - Biotech patent dispute settled
Pediatrics - Strategies for assessing child neglect reported
Anthrax - FDA issues final order on safety of bacterial vaccines and toxoids
Legal Issues - Doctors, employees seek to keep Philadelphia hospital open
Legal Issues - Insurer fires back at state claims in lawsuit
Leptin Studies - Rats have defective central leptin signaling before obesity onset
Leukemia - ALL leads to reduced bone volume and trabecular thickness in children
Leukemia - LISA set to transform children's cancer care
Leukemia - One-fifth of infectious deaths in children with ALL are due to fungal infections
Leukocyte Function - Tetraspanins form functional cell surface microdomains in leukocytes
Liver Cancer - A high percentage of liver cancers have elevated liver-intestine cadherin
Liver Disease - Caveolins regulate bile salt and cholesterol metabolism
Liver Transplantation - ICAM-1 is not linked to liver allograft ischemia-reperfusion injury
Anthrax Vaccine - Flow cytometric assay for responses to anthrax vaccine developed
Liver Transplantation - Imaging can detect complications of liver transplantation
Liver Transplantation - Splenic aneurysm after liver transplant may be treated by embolization, glue
Long QT Syndrome - New genetic "hit list" may underlie susceptibility to sudden cardiac death
Low Birth Weight - Heart rate irregularities in some babies may signal the onset of sepsis
Lumbar Spine Density - Researchers evaluate the clinical utility of dual-energy vertebral assessment
Lung Cancer - Aspirin use does not reduce lung cancer risk in men
Lung Cancer - Certain GST genetic polymorphisms are related to increased lung adenocarcinoma
Lung Cancer - Clinical trial under way for patients with brain metastases
Lung Cancer - NSCLC tumor response to chemotherapy can be assessed using RECIST guidelines
Lung Cancer - Researchers detect lung cancer in plasma with multiple genetic markers
Anti-Infectives - FDA approves manufacturing and marketing of Cefaclor Tablets, Chewable
Lung Cancer - Risk factors for acute lung injury after lung cancer surgery are identified
Lung Cancer - SOCS-3 is suppresses cell growth in human lung cancer
Lymphocyte Activation - Paracaspase is involved in B cell and T cell NF-kappa B-dependent activities
Lymphocyte Maturation - Activated Notch2 is involved in CD8 T-cell maturation, selects for B1 B cells
Lymphocyte Migration - IL-16 acts on CD4 associated with CCR5, inducing Th1 cell migration
Lymphoma - BRAF mutation may aid tumor development in some non-Hodgkin lymphoma
Lymphoma - Researchers assess expression of B-cell markers in classical Hodgkin lymphoma
Malakoplakia - Cervical malakoplakia is treatable by excision, antibiotics for E. coli
Malaria Diagnostics - Abbott Cell-Dyn 4000 useful for therapeutic monitoring of malaria patients
Malaria Drug Resistance - Novel pfcrt mutations seen in P. falciparum from the Philippines
Anti-Inflammatory - Binding site for anti-inflammatory tripeptide feG identified
Malaria Enzymology - Lipid-binding domain of PfCCT characterized
Malaria Immunology - In asymptomatic patients, IL-12 suppresses parasitemia and NOS activity
Malaria Therapy - Antiviral effects of chloroquine reviewed
Malaria Therapy - Combination drug therapy offers hope for millions
Measles - Health official plays down reports of Central African Republic epidemic
Measles Vaccine - ELISA and virus neutralization assay yield same measles antibody titers
Medical Devices - New agreement signed for "smart pump" devices
Medical Malpractice Insurance - Insurer raises malpractice rates in Florida by 45%
Medical Malpractice Insurance - Pennsylvania doctors to continue paying insurance
Medical Malpractice Insurance - University hospital, doctors form malpractice insurance company in Kentucky
Anti-Inflammatory Agents - CX-659X uracil compounds have topical anti-inflammatory potency like tacrolimus
Medical News - Harvard rates top 10 health/medical stories of 2003
Medical Technology - Global healthcare technology company chooses parts management company
Medical Technology - High technology trade fair to be held in Germany
Medical Waste - Joint venture negotiations for diagnostic software initiated
Melanoma - Agents directed at actin assembly would stop tumor aggression
Melanoma - Carboplatin and temozolomide have high toxicity in advanced melanoma patients
Melanoma - PET scanning can assess extent of disease in patients with metastatic melanoma
Meningioma - RT-PCR assay can rapidly identify telomerase RNA in intracranial meningiomas
Meningococcal Meningitis - BLA submitted for approval of Menactra
Menopause - Aromatase activity helps to maintain bone health after menopause
Antibiotic Research - Study of E. coli given cecropin B reveals antibiotic's mode of action
Menopause - Parathyroid hormone gene therapy may stop osteoporosis in postmenopausal women
Menopause - Some women turn to antidepressants to quell hot flashes
Mental Health - FDA approves medication for bipolar depression
Mental Health - Gestational stress harms maternal behavior in rodent models
Mental Health - Milestone payment resulting from depression and anxiety drug collaboration
Mental Health - The GHQ-12 assessment tool can't score pregnant and postpartum women adequately
Mergers and Acquisitions - Biopharmaceutical service company acquired
Mergers and Acquisitions - CRC Health Group acquires National Specialty Clinics
Mergers and Acquisitions - Drug discovery companies announce merger
Mergers and Acquisitions - European pharmaceutical sales, marketing business sold for $120M
Antibody Drug Conjugates - Exclusive antigen license taken under antibody drug conjugate collaboration
Mergers and Acquisitions - Express Scripts, CuraScript announce acquisition agreement
Mergers and Acquisitions - Healthcare management and healthcare services companies announce $80 million merger
Mergers and Acquisitions - Implant product manufacturer announces termination of acquisition negotiations
Mergers and Acquisitions - Insurer acquires provider of health insurance coverage to college students
Mergers and Acquisitions - Lab services and instrumentation company makes acquisition
Mergers and Acquisitions - Nutrition company completes acquisition
Mergers and Acquisitions - Pharmaceutical firms receive FTC request for information on transactions
Metabolic Syndrome - Genetic markers may signal a predisposition to metabolic syndrome
Metastatic Melanoma - Nitric oxide-mediates hypoxia-induced B16F10 melanoma metastasis
Molar Pregnancy - High-resolution vaginal ultrasonography may detect molar pregnancy
Antifungals - Terbinafine HCl Tablets receives tentative FDA approval
Monoclonal Gammopathy - IgM monoclonal gammopathy increases the risk for lymphoma and other diseases
Mosquito-borne Disease - Marsupials help prevent establishment of Japanese encephalitis in Australia
Multiple Myeloma - Breakthrough discovery puts researchers closer to cure for multiple myeloma
Multiple Myeloma - Survey shows low enrollment of multiple myeloma patients into clinical trials
Multiple Myeloma - Thalidomide Pharmion approved in New Zealand
Multiple Sclerosis - A genome screen of multiple sclerosis reveals 22 associated markers
Multiple Sclerosis - A genome-wide screen in HLA-DRB1*1501 positive MS patients yields three new links
Multiple Sclerosis - A genomic screen reveals 191 genes, 11 in the MHC region, linked to MS
Multiple Sclerosis - A linkage disequilibrium screen reveals 12 possible multiple sclerosis markers
Antigen Presentation - Full T-cell expansion, function require days of exposure to antigen complex
Multiple Sclerosis - A whole genome screen including families reveals only one sure gene linked to MS
Multiple Sclerosis - A whole genome study associates 91 markers with multiple sclerosis
Multiple Sclerosis - A whole genome study reveals 108 markers associated with multiple sclerosis
Multiple Sclerosis - A whole genome study reveals 46 genes associated with multiple sclerosis
Multiple Sclerosis - Confounding factors need to be worked out of MS whole genome linkage mapping
Multiple Sclerosis - Genetic screens reveal nine markers potentially related to multiple sclerosis
Multiple Sclerosis - Genomics research reveals 10 genes associated with multiple sclerosis
Multiple Sclerosis - Linkage analysis of families with MS shows chromosome 10, 10p15 involved
Multiple Sclerosis - MMP-9 degrades endogenous, therapeutic IFNbeta in MS; may be therapeutic target
Multiple Sclerosis - MS patient PBMC have decreased mRNA of apoptosis regulators CD95, caspase-8
Antigen Presentation - Uptake of polioviral RNA creates antigen by neosynthesis, specific CTL result
Multiple Sclerosis - Targeting of chemokine receptors may be able to control multiple sclerosis
Multiple Sclerosis - Two genome-wide screens of high risk Sardinians show five genes linked with MS
Multiple Sclerosis - Whole genome study of consanguineous Turkish MS families finds linked regions
Mumps - Mumps can be detected by IFA or shell vial culture of throat swab, urine
Murine Ehrlich Ascites Tumor - Tumor growth was delayed 4-6 days by treatment with 5-FU and ultrasound
Murine Melanoma - Fyn and cortactin cooperate in cell migration of metastatic murine melanoma
Muscle Diseases - Mixed connective tissue disease may have pathology due to lymphoid follicle
Myelodysplasia - Study looks at immune-suppressing treatments
Myelodysplastic Syndrome - Enrollment stopped for myelodysplastic syndromes monotherapy trial
Myelodysplastic Syndrome - New drug application submitted to market myelodysplastic syndromes therapy
Reproductive Biology - Researchers find gene key to production of egg and sperm
Antigen-Presenting Cells - APC-expressed indoleamine 2,3-dioxygenase degrades tryptophan; lowers atopy
Myelodysplastic Syndrome - Trial will compare Daclizumab to ATG to treat the cytopenia of myelodysplastic syndrome
Myocardial Infarction - Company seeks new drug indication for treatment of heart attack survivors
Nanoscience - University lands role in $70 million network for nanotechnology research
Narcolepsy - Hypocretin receptor 2 may be attacked in high-axon regions in human narcolepsy
Nausea - Addition of aprepitant to cisplatin improves chemo patients' quality of life
Nearsightedness - Review date set for phakic intraocular lens premarket approval application
Necrotizing Vasculitis - Respiratory problem testing for ANCA may find early Wegener granulomatosis
Needlestick Injury - LiftLoc safety infusion set product receives ISO Certification and CE Mark
Needlestick Prevention - ECRI, Novation team up to provide needlestick prevention information
Neurodegeneration - Role of CREB in neurodegeneration reviewed
Antimicrobial Peptides - Cathelicidins vary in resistance to proteolysis; some have sustained activity
Neurology - Epilepsy drug candidate begins phase I clinical development
Neurology - Lumbar epidural hematoma, falling, other trauma can cause acute paraparesis
Neurology - Neurotrophic and angiogenic growth factors augment electroconvulsive therapy
Neurology - Research may help stroke survivors with uncontrolled emotions
Neuroscience - Anoxic births foreshadow dopamine-related behaviors after puberty
Neuroscience - Gender and employment environment correlate with Parkinson disease epidemiology
Neuroscience - Layering defect linked to improper neuronal-glial interaction
Neuroscience - Neuropsin is novel opsin identified in mammalian neural tissue
Neuroscience - Overexpressed antioxidant enzymes protect nerve cells from necrotic insults
Neuroscience - Sickle red blood cells prefer to accumulate in tumor vessels
Antimicrobials - Analyst report recommends pharma company
Neutrophil Cytotoxicity - SLP-76 is essential for reactive oxygen intermediate formation in neutrophils
Norovirus - CDC: Nearly 65 passengers on cruise ship get stomach illness
Nutrition - Nearly one in four women make New Year's resolution to eat healthier
Obesity - Researcher gets $1 million to study thin people
Obesity - Researcher links rising tide of obesity to food prices
Obesity - Role of ectopic lipids in the metabolic syndrome reviewed
Obesity Diagnosis - Screening recommendations for obesity in adults released
Obesity Risk Factor - Early intrauterine exposure to tobacco increases obesity risk
Obesity Surgery - New techniques available for open-surgery management of morbid obesity
Obesity Therapy - Peripheral GLP-2 has no effect on gastric emptying or satiety
Antimicrobials - Lentivirus lytic peptide derivatives selectively toxic to airway pathogens
Obstetrics - Full placenta previa worsens pregnancy outcomes
Obstetrics - More episiotomies performed by private doctors than residents, hospital faculty
Obstetrics - Short-term exercise has little impact on fluid regulation during pregnancy
Obstetrics - Social and psychological factors predict alcohol use during pregnancy
Obstetrics - The Cambridge Worry Scale is reliable for assessing pregnant women
Obstetrics - Two midwives to run center in Iowa
Obstetrics - Urgent action required to prevent half a million maternal deaths annually
Occupational Safety - Hands may contain clues about fluorine poisoning
Oncology - Antisense inhibition of VEGF blocks leukemia angiogenesis and growth
Oncology - Cyclooxygenase 2 and survivin are often coexpressed in lung cancers
Antimicrobials - New classes of antibacterial oxazolidinones reported
Oncology - Multimodal therapy works well for treating caudate hepatocellular carcinoma
Ophthalmology - Different eye area DC have different abilities to react, be tolerant of antigens
Ophthalmology - FDA issues approval letter for dry eye treatment
Ophthalmology - Gender-specific gene polymorphisms associate with uveitis symtomatology
Ophthalmology - Intact sensory nerves are required for vascular remodeling after sympathectomy
Ophthalmology - Laser system selected for LASIK centers nationwide
Ophthalmology - Study: Primary care physicians not sending children with vision problems to the eye doctor
Ophthalmology - Vitamin E may combat macular degeneration
Opportunistic Infection - Etest suitable for Aspergillus voriconazole resistance testing
Oral Cysts - MR imaging of oral and maxillofacial cysts gives more information than X-rays
Antineoplastic Agents - A closed-system protective device reduces exposure to antineoplastic agents
Osteoarthritis - Chondrocyte HO-1 is regulated by cytokines depending on inflammatory properties
Osteoporosis - ANDA submitted for hormonal nasal spray that may combat osteoporosis
Osteoporosis - Agreement extended to collaborate on selective androgen receptor modulators
Osteoporosis - Calcium and sodium regulation supports osteoporosis and hypertension therapies
Osteoporosis - Extracts of Cortex Eucommiae augment bone growth and suppress bone loss
Otology - Major developments to improve hearing health reported
Outbreaks - Enrichment culture could aid laboratory detection of C. perfringens
Outbreaks - Rate and severity of serogroup X meningococcal meningitis in Niger clarified
Ovarian Cancer - Oral capecitabine is safe and effective in recurrent ovarian cancer
Ovarian Tumors - B-scan ultrasound is effective in evaluating ovarian masses
Antisense Technology - Antisense oligodeoxynucleotides to p53 and p21 augment cancer radiotherapy
Pain Management - FDA approves generic oxycontin
Pain Medicine - A woman's beliefs about childbirth rules labor anesthesia choices
Pain Medicine - Economic impact of back pain substantial
Pancreatic Cancer - Irinotecan plus cisplatin in advanced pancreatic cancer had severe toxicity
Pancreatic Carcinoma - Pancreatic head carcinoma may be difficult to differentiate from pancreatitis
Pancreatic Islets - Interactions of polymeric sulfonylurea with pancreatic islets examined
Parkinson Disease - Alpha-synuclein interacting protein gene and Parkinson disease studied
Patents - Patent announced for chewable oral contraceptive
Pediatric AIDS - More effective prenatal care could halt perinatal transmission of AIDS
Antitumor Agents - Vitamin E succinate may be a prototype for selective antitumor activity
Pediatric Obesity - Panel set to rid Florida schools of junk food
Pediatric Obesity - U.S. has highest prevalence of overweight teens in 15-country study
Pediatrics - Parental alcohol abuse has long-term consequences for offspring
Pediatrics - Reduced vitamin K doses would still benefit premature infants
Peptides - Vasoactive intestinal peptide blocks chemokine receptors
Perinatal HIV - Rapid HIV tests for women in labor studied
Perinatal Medicine - Neonatal care and practices have improved over the last 25 years
Personnel - Administration changes made at trade association
Personnel - American Physicians Capital board appoints new president, CEO
Personnel - Biopharma announces two executives
Antitumor Therapy - RNA aptamers can bind and inhibit CTLA-4, increasing antitumor activity
Personnel - Biotech firm appoints renowned biochemist to scientific advisory board
Personnel - Cardiovascular drug development company announces election of directors
Personnel - Chief financial officer resigns from biotech firm
Personnel - Cron named VP of surgical division at device firm
Personnel - Healthcare information management firms announced board resignation
Personnel - Imaging company technology officer steps down
Personnel - Medical device manufacturer announces new member to board of directors
Personnel - New consultant in transfusion science appointed
Personnel - New executive named for Illinois foundation
Personnel - New genomics executive named
Anxiety - Effexor XR provides long-term treatment of generalized anxiety disorder
Personnel - New health information company executive named
Personnel - New president named for biometric signature authentication firm
Personnel - Oregon BCBS announces executive changes
Personnel - Pain management company announces executive appointments
Personnel - Pharmaceutical company announces new chief business officer
Personnel - Pharmaceutical company founder and chairman steps down to nonexecutive role
Personnel - Risk management company names head of investigative services
Personnel - Rosa named VP, strategic development at molecular fingerprinting company
Personnel - Silverstein joins board of directors at pharmaceutical company
Personnel - Spineology names Jim Rybicki as vice chairman of the board
AIDS Epidemiology - American Indians see rapidly climbing AIDS infection rates
Apoptosis - Peptide increases arachidonic acid release and apoptosis of muscle cells
Personnel - Surgical company announces change in board of directors
Personnel - Therapeutics company announces management changes, promotions
Personnel - Tissue regeneration company appoints new board member
Personnel - Two new board members named at drug delivery company
Personnel - U.S. Dept. of Health & Human Services appoints National Advisory Council member
Pharmaceutical & Drug Development - The lambda-dynamics method improves analysis of HCV protease inhibitors
Photomedicine - Early-stage photodynamic therapy doesn't harm outer retinal function
Podiatric Surgery - Study shows reduced pain and narcotic use following foot and ankle surgery
Policy - Mozambique: U.N. human rights expert decries discrimination against AIDS patients
Population Descendance - Genetic markers show Iranian speakers in Azerbaijan related most to Azerbaijanis
Apoptosis - Targeting lipid raft protein distribution may control apoptosis
Preeclampsia - High PLA2 levels in decidual tissue may underlie acute atherosis
Pregnancy Complications - Mast cell degranulation supports anaphylaxis as result of amniotic embolism
Premature Birth - Alliance to provide care management for high-risk neonates
Prescribing Practice - Researchers update Beers criteria for medications to avoid in the elderly
Prescription Drugs - Companies announces new prescription information alliance
Prion Disease - Helix 1 peptide elicits antibodies against prion protein in mice
Professional Development - Cultural training increases competence of nonminority psychologists
Prostate Cancer - Adenoid cystic/basal cell carcinoma of the prostate requires ablative treatment
Prostate Cancer - CHEK2 gene variants play a role in hereditary prostate cancer
Prostate Cancer - Canadian company announces Phase II clinical study of prostate cancer treatment
Arthritis - Study identifies biological markers among patients with high risk of joint damage
Prostate Cancer - Cancer vaccine manufacturer obtains rights to Biogen Idec LFA-3 patents
Prostate Cancer - Erectile dysfunction affects quality of life after radical prostatectomy
Prostate Cancer - Green tea may be protective against prostate cancer
Prostate Cancer - Mayo Clinic presents results from the familial prostate cancer study
Prostate Cancer - Repeating the measurement of PSA symptomatic men can avoid unnecessary biopsy
Prostate Cancer - Scan of hereditary prostate cancer families finds dominant locus at 6p22.3
Prostate Cancer - Too much, too little vitamin D both increase prostate cancer risk
Prostate Cancer - p300 is important in prostate cancer proliferation and progression
Prosthetics - Hydraulic knee frame reintroduced to market
Proteomics - Approach to unnatural insertion of amino acids into proteins proposed
Arthritis Pathogenesis - Arthritis-regulating quantitative trait locus on rat chromosome 6
Proteomics - JNK and ERK activation in rabbit hippocampus is regulated by lithium
Proteomics - Neovastat stimulates tissue plasminogen activator activity
Proteomics - RACK1 gene regulated by nuclear factor-kappa B and promotes cell survival
Proteomics - Screening platform for protein analysis in intact cells developed
Proteomics - The death effector domain protein family may control life and death of cells
Pseudomonas - Scaffolds increase activity of efflux pump inhibitors against Pseudomonas
Psoriasis - Immunotherapeutic treatment for psoriasis discontinued
Psoriasis - PVAC program is discontinued due to lack of clinical benefit
Psoriasis - Study may indicate a new direction for psoriasis research
Psychology - Demographics link alcohol consumption risk and use by pregnant women
Assisted Reproduction - A CD16+CD56DIM NK cell increase may lead to idiopathic infertility
Psychology - Negative marriage interaction prefaces inadequate transition to parenthood
Psychology - Sense of Coherence surveys of college students lead to questions of validity
Pulmonary Embolism - MR angiography is useful for diagnosing pulmonary embolism
Pulmonary Medicine - Death certificate underestimates impact of obstructive lung disease on mortality in U.K.
Rabies - Disease remains a costly public health threat, says virologist
Receptor Studies - Gastrointestinal functions of proteinase-activated receptors reviewed
Receptor Studies - Role of proteinase-activated receptors in nervous system reviewed
Regulatory Issues - Paper: U.K.'s new National Health Service act will restrict choice of treatment location
Rehabilitation Medicine - Running a-fowl: Researchers measure energy used by leg muscles
Renal Medicine - Link between hyperhomocysteinemia and CVD in renal patients reviewed
Asthma - Corticosteroids do not appear to prevent early bronchial remodeling
Renal Transplantation - Renal transplant patients with headache may have intracranial hypertension
Reproduction Medicine - More use of sex-diagnostic techniques might change the gender ratio in India
Research Bias - Researchers find bias in radiologic studies
Respiratory Illness - Human metapneumovirus is responsible for many respiratory tract illnesses
Respiratory Syncytial Virus - Palivizumab and RSV-IGIV indications for respiratory syncytial virus revised
Restenosis - Positive phase II clinical results reported in trial of Resten-NG
Retinopathy - Thrombospondin-1 is essential for appropriate retinal vascular remodeling
Rheumatoid Arthritis - HLA-DRB1*04 mutations disrupt stem-cell function
Rheumatoid Arthritis - Heat shock proteins for immunotherapy of rheumatoid arthritis reviewed
Rheumatoid Arthritis - Long-term study suggests vitamin D may help reduce older women's risk
Asthma - Exposure of babies to mite, cat can lead to asthma; repeat rhinitis lowers risk
Rosacea - Finacea 15% gel approved in E.U. countries
SARS - Angiotensin-converting enzyme 2 acts as receptor for SARS virus
SARS - Researchers assess putative protein targets derived from the SARS genome
SARS - Severe acute respiratory syndrome -associated coronavirus vaccine shows promise in monkeys
SARS - WHO wants China's suspected SARS case tested overseas
Saccharomyces - Saccharomyces cerevisiae transcription factor defective in spt7 mutants
Salmonella Enterica - SopE, encoded outside the Salmonella SPI-1, is still chaperoned by InvB
Salmonellosis - U.S. outbreak of Salmonella enterica linked to mango consumption
Sarcoidosis - Refractory sarcoidosis may improve with infliximab therapy
Asthma - Long-term childhood asthma is likely to carry into adult asthma or wheezing
Schizophrenia - Human frizzled-3 gene on chromosome 8p21 linked to schizophrenia
Schizophrenia - Yeast two-hybrid screens implicate DISC1 in brain development and function
Senior Fitness - Pennsylvania insurance plan offers senior fitness program
Short Bowel Syndrome - Cell proliferation and survival occur via activation of GLP-2 receptors
Simian Immunodeficiency Virus - Development of SIV in sooty mangabey monkeys characterized
Simian Immunodeficiency Virus - Origins of mandrill- and drill-derived SIV reviewed
Sinusitis - Trichoderma longibrachiatum can be a cause of sinusitis, atopy, and asthma
Sinusitis - OTC nasal wash shown helpful in treatment of sinus sufferers
Skin Cancer - Researchers measure daily UVB exposure in students using digital dosimeters
Skin Cancer - Winter outdoors fans urged to use sunscreen
Asthma - Recurrent wheezing higher in infants who show reduced interferon, plus less IFN-gamma
Smallpox - Researchers intrigued by century-old smallpox scabs
Sociology - Gender influences perceptions of social support
Spine Lesions - F-18FDG PET is highly predictive for spinal metastases or benign lesions
Squamous Cell Carcinoma - Smad7 cooperates with oncogenic ras in malignant conversion of murine SCC
Stem-Cell Research - Artemisinin staunches angiogenic effects in murine embryoid bodies
Stem-Cell Research - Candidate genes for maintenance of embryonic stem cell pluripotency identified
Stem-Cell Research - Embryonic stem cells can replace ear "hair" cells
Stem-Cell Research - Hematopoietic stem cells provide superior repopulation in mice
Stem-Cell Research - Main-population cells account for vast majority of Sk-34 cell activity
Atherosclerosis - Gene worsens artery disease
Stem-Cell Research - Modified stem cells relieve motor symptoms in a Parkinson disease model
Stem-Cell Research - P-selectin and ICAM-1 influence regulatory T-cell development
Stem-Cell Research - Serum-free medium with SCF can produce mature cord blood-derived mast cells
Stem-Cell Research - Thrombopoietin regulates early neutrophil differentiation
Stem-Cell Research - Types and activity of mammary epithelial progenitor cells reviewed
Stem-Cell Transplantation - Rhinolalia can mark dangerous post-SCT pulmonary complications
Stroke - Intra-arterial clot-dissolving therapy improves results of early stroke treatment
Systemic Lupus Erythematosus - Knowledge of the genetic basis for SLE has helped analysis of complex disease
AIDS Prevention - Mauritania: Imams join low-key campaign against AIDS
Atrial Fibrillation - ACP and AAFP release joint clinical guidelines to manage common heart condition
Systemic Lupus Erythematosus - Thromboembolism in pediatric lupus linked to anticoagulant
T-Cell Function - Venezuelan EEV replicons increase CD56+ T cells with NK-like activity
T-Cell Proliferation - T-cell apoptosis can be induced by cell cycle regulator p21 or peptide DQ 65-79
Testicular Cancer - Testicular microlithiasis is associated with germ cell tumors
Thrombosis - FDA approves lab tests for genetic clotting risk
Thrombus - Pronto extraction catheter receives 510(k) clearance from FDA
Thyroid Cancer - PP1 inhibitor targets RETMEN2A and RETMEN2B oncoproteins
Thyroid Cancer - Radioiodine increases risk of solid tumors, leukemias in thyroid cancer patients
Thyroid Cancer - Well-differentiated thyroid cancer can transform into an anaplastic tumor
Thyroid Tumors - Hurthle cell tumors composed of onocytes remain to be defined
Autoimmune Disease - Autoreactive B cells infected with EBV may be key to chronic autoimmune disease
Thyroid Tumors - Researchers explore the molecular basis of thyroid epithelial tumorigenesis
Tonsillar Cancer - HPV is not found in all tonsillar squamous cell carcinoma patients
Total Joint Arthroplasty - Researchers analyze ground reaction forces before and after TKA & THA
Total Knee Arthroplasty - Bone cement induces an increase in serum astroglial S-100B protein in TKA
Toxicology - "Homegrown" relief may aid victims of arsenic poisoning in South Asia
Toxicology - Bisphenol A metabolite levels in urine are gender-dependent
Transplant Medicine - Synthetic "antifreeze" could better preserve human cells and tissues
Transplant Medicine - Tacrolimus levels increase as a result of steroid withdrawal
Transplant Medicine - Transplant clinic expands services
Transplantation - Donations of both blood and tissue may yield better liver graft results
Autoimmune Disease - CNS autoimmune disorders may benefit from the statin anticholesterol drugs
Transplantation - Maintenance lamivudine lowers risk from HBV antibody-positive liver grafts
Transplantation - Refractory acute rejection thwarts some living liver graft implantations
Travel Medicine - U.K. public health agency issues reminder to travelers over malaria
Trypanosoma - Structure of thioredoxin from Trypanosoma brucei brucei determined
Trypanosomiasis - Diagnosing sleeping sickness outside Africa is difficult
Tuberculosis - M. tuberculosis ethA and inhA gene mutations linked to ethionamide resistance
Tuberculosis - Lupus vulgaris can mimic wide array of conditions
Tuberculosis - TB-induced gastroduodenal artery pseudoaneurysm reported
Tuberculosis Genomics & Genetics - M. tb strains have differential PE, PE_PGRS gene expression
Tuberculosis Immunology - Novel CD8 cell epitope shared by M. tuberculosis ESAT-6 proteins
Autoimmune Disease - EEA1 has many B cell epitopes; neurological disease may occur if at C terminal
Tuberculosis Pathogenesis - Differential mycobacterial gene expression seen in mice and humans
Tuberculosis Pathogenesis - Factors involved in failure of anti-TB immunity identified
Tuberculosis Therapy - CDC study will compare short versus long-term TB treatment regimens
Tuberculosis Therapy - Voltammetric assay provides accurate measure of isoniazid levels
Tuberculosis Vaccine - recA deletion mutant of M. bovis BCG confers protection
Tumor Angiogenesis - Delivering cationic liposomes to tumors improves antiangiogenic therapy
Tumor Growth - Small molecule shown to inhibit tumor growth in preclinical models
Tumor Necrosis Factor - There are several multimeric forms of RANKL involved in osteoclastogenesis
Tumorigenesis - The Bcl-2 family primarily determines cell survival
Type 1 Diabetes - Lymphocytic choriomeningitis virus infection stops diabetes in mice
Autoimmune Disease - Parasite lipids could be used against asthma or diabetes
Ulcers - The nitrite anion has role in mucous production
Urinary Tract Infections - Phase III trial begins with Doripenem in complicated urinary tract infections
Uveal Melanoma - MC1R variants do not appear to be related to uveal melanoma
Vaccine Adjuvant - CpG-containing oligodeoxynucleotides increase adjuvant effects
Vaccine Development - Tumor cell vaccines containing nonviral vectors offer cancer prevention
Vaccine Efficacy - Cost-utility analysis of vaccine strategies in Switzerland released
Vaccine Safety - Vibrio cholerae toxins activate proinflammatory immune response
Vaccines - Investigational new drug application to be filed for HIV vaccine
Varicella Vaccine - Incidence of herpes zoster in children reported
Vascular Endothelium - Activated lymphocyte, neutrophil migration may be regulated by L-selectin
Autopsy - Autopsy imaging may provide more precise information about final diagnosis
Vector Development - Moderate retroviral transduction limits the potential for multiple insertions
Vectors and Zoonoses - Genetic variation in Aedes aegypti characterized
Vectors and Zoonoses - Single gene encoding VDAC protein identified in Anopheles gambiae
Venous Thromboembolism - New drug application submitted to FDA for Exanta
Viral Genomics - Common antivirals can't totally block hepatitis B virus infection
Viral Genomics & Genetics - South American dengue-1 viral genotypes determined
Viral Hepatitis - Estrogen exposure may confer protection against liver cancer
Viral Proteomics - Antivirals are tools for analyzing hepatitis B virus genomic replication
Viral Proteomics - Hemagglutinin uses "leash in the groove" mechanism for membrane fusion
Virology - Effects of GBV-C co-infection on HIV progression reviewed
Awards - Thompson honored for his contributions to medicine, public health
Waste Treatment - Recycling company looks to expand business in China
Water-borne Disease - Novel assay improves detection of Cryptosporidium in water
Weight Loss - Pilates and paella: Gyms selling food plans to help members lose weight
Wound Care - Oxygen exposure improves wound healing rate
Bacteriology - Amino acids and peptides may help protein removal and innate lung defense
Bacteriology - Chemical signaling among bacteria and its inhibition reviewed
Bacteriology - DNA-membrane interactions can localize bacterial cell center
AIDS Therapy - DSMB recommends continuation of phase I trial with VRX496 modified T cells
Bacteriology - Needle length of bacterial injectisomes determined by molecular ruler
Behavior - Kids exposed to violence have more behavioral problems
Behavioral Medicine - Factors affecting validity of self-reports among adolescents determined
Biodefense - Landmine sensor to be tested by U.S. Army
Biodefense - Safe room kit available for home protection
Bioengineering - Continuous delivery of microencapsulated interleukin-1 diminishes angiogenesis
Bioengineering - VEGF gene transfer enhances the function of implantable sensors
Blood Pump - Researchers test a centrifugal blood pump with a magnetic bearing
Blood Safety - Japanese transfusion recipient infected by HIV-tainted blood
Blood Substitute - Patient enrollment begins for urban ambulance/blood substitute trial
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