Saccharomyces

Saccharomyces cerevisiae transcription factor defective in spt7 mutants

Published in Health and Medicine Week, January 19th, 2004

Transcription of TIM9, a new factor required for the petite-positive phenotype of Saccharomyces cerevisiae, is defective in spt7 mutants.

According to a study from Australia and the United States, "TIM9 has been identified as an additional novel gene required for the petite-positive phenotype in Saccharomyces cerevisiae. tim9-1 was obtained through a screen for respiratory-deficient strains that are unable to survive in the absence of mitochondrial DNA. A point mutation found in the tim9-1 coding region converts codon 71 from Gly to Arg."

"Examination of genes encoding other Tim components indicated that the temperature-conditional...

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Source: Health and Medicine Week (2004-01-19)

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