Susan Hasty, Publisher
Table of Contents . . . February 9th, 2004
Non-Subscriber - Summaries OnlyRelated Areas: Other Issues in Health and Medicine Week | Other Publications
Nutrition - Eggplant found to have an antioxidant kick
AIDS Infection - Bulgarian medics trial postponed
Breast Cancer - Increased Bim mRNA and protein can cause apoptosis in breast cancer cells
Breast Cancer - Magnetic resonance imaging detects more tumors
Breast Cancer - Normal HC11 and ras-transformed mouse mammary cells are resistant retinoic acid
Breast Cancer - Pathologic study of reduction mammaplasty tissue should be performed routinely
Breast Cancer - Proteins and antibodies licensed for human cancer research
Breast Cancer - Radiotherapy improves survival after early stage, breast-conserving surgery
Breast Cancer - Review of patient-tailored cancer treatment completed
Breast Cancer - Symposium calls for improved access to screening, treatment across Europe
Breast Cancer - Trial seeks patients in Southern California
Breast Implants - Breast implant prosthesis may offer alternative to saline and silicone
AIDS Research - Thailand rejects criticism of AIDS vaccine trial
Breast and Lung Cancer - Salivary-type neoplasms of the breast and lung need further molecular study
Bronchogenic Carcinoma - Exercise testing may predict surgical risk of pneumonectomy
Burn Medicine - Pediatric burn patients need vitamin D supplements
Business & Finance - Blue Cross profits among fastest-rising in early 2003
Business & Finance - Firm acquires Nevada medical center from Tenet
Business & Finance - HMO's move could push more in Missouri, Kansas to high-risk insurance pools
Business & Finance - Managed care medical directors, execs rank drug firms by ability to meet needs
Business & Finance - NABN selects disease management programs and services provider
Business & Finance - Plan realizes major ROI with care-management decision support
Business & Finance - South Carolina healthcare nonprofit plans to file for bankruptcy
AIDS Therapy - IND application filed for protease inhibitor GS 9005
Business & Finance - Subsidiary question kills health insurance transfer
Business & Finance - Trustees reach agreement for company to operate Oklahoma hospital
Cancer Cell Biology - Scientists identify cell defects that limit immune system's impact on late-stage tumors
Cancer Databases - Center goal is to speed detection, treatment and prevention of cancer
Cancer Epidemiology - Using established epidemiological methods can best answer molecular questions
Cancer Fraud - Ohio woman sentenced for faking cancer and collecting donations
Cancer Incidence - Exposure to high levels of trichloroethylene may be increase risk of NHL
Cancer Metastasis - PTEN gene inactivation associates with breast cancer dissemination
Cancer Outcomes - Patients enrolled in cancer trials do not necessarily fare better
Cancer Research - U.K. program for clinical research launched in London
AIDS Treatment - AIDS activists fight for more affordable drugs
Cancer Surgery - Excisional surgery for cancer cure may have adverse effects
Cancer Symptoms - Researchers summarize mechanisms underlying cancer-induced symptoms
Cancer Therapy - CRADA inked for pancreatic, ovarian, and lung cancer antibody development
Cancer Therapy - Company reports on mechanism for immunotherapy cure of prostate cancer
Cancer Therapy - DFMO did not improve outcomes in superficial bladder cancer study
Cancer Therapy - Patent granted for humanized CEA antibody conjugates
Cancer Therapy - The cytocidal gene construct rexin-G arrests pancreatic tumor growth
Cancer Therapy - Therapies that control VEGF production look appealing for treating cancer
Cancer Vaccine - Cancer vaccine delivers antigen to dendritic cells
AIDS Treatment - Companies agree to drop price of AIDS-combating drugs sold to Brazil
Carcinogenesis - Arsenic is associated with increased cancer incidence
Cardiac Safety Testing - Company can help clients meet FDA cardiovascular requirements
Cardiac Surgery - Brain injury during adult cardiac surgery may be reduced
Cardiology - Clonal embryonic cardiac development characterized
Cardiology - Embryonic atrial function steers embryogenesis, cardiac growth, and angiogenesis
Cardiology - Enhanced permeability explains reduced calcium uptake in cardiac mitochondria
Cardiology - Function of FGF8 during embryonic development elucidated
Cardiology - GATA4 triggers cardiomyocyte development in Xenopus explants
Cardiology - Inotropic, chronotropic responses vary during dobutamine stress echocardiography
Cardiology - Nkx2.5 regulates Cx43 expression in neonatal cardiomyocytes
AIDS and HIV - Gene product restricts HIV-1 replication in resting CD4+ lymphocytes
Cardiology - Polyurethane implants deliver site-specific therapy with tethering systems
Cardiology - Sorcin gene therapy reverses cardiac function in diabetes-linked heart disease
Cardiovascular Disease - Aging, heart failure reduce cutaneous vascular reactivity
Cardiovascular Disease - Colchicine can cause kidney damage in heart failure patients
Cardiovascular Disease - D-dimer levels predict cardiovascular events in AF patients on OAT
Cardiovascular Disease - Late sequela of infective endocarditis possible
Cardiovascular Disease - NAD(P)H oxidase p22 phox mutations do not affect CVD risk
Cardiovascular Disease - Optimal CFVR cut-off for LAD stenosis diagnosis identified
Cardiovascular Disease - Role of P-selectin in atherogenesis reviewed
Catheter Systems - Company announces market release of two left-heart delivery systems
Accreditation - First Health receives URAC accreditation for health provider credentialing
Cell Biology - Angiomotin enables endothelial cells to respond to chemotactic cues
Cell Biology - Findings uncover workings of cell's energy machinery
Cell Biology - Gene causing tumors by "double-whammy" mechanism also reveals the key to a cure
Cell Biology - Vascular endothelial growth factor receptor-1 fosters matrix protein activity
Cell Biology - Wnt-1 signals could be major players in angiogenesis regulation
Cell Signaling - Complete picture of a human immune pathway revealed
Cell Transduction - A unique coculture system improves in vitro investigations of gene therapy
Cerebral Malaria - Misdiagnosis common in patients who die after coma
Cervical Cancer - Cervical cancer staging is based on clinical, anatomic disease extent
Cervical Cancer - Cervical neoplasia is an HPV-associated malignancy
Acute Myocardial Infarction - Research focuses on drug-free heart attack prevention
Cervical Cancer - Chemotherapy for carcinoma of the cervix has improved outcomes
Cervical Cancer - Clinical trial data show noninvasive technology could reduce false positives
Cervical Cancer - Combined therapy is standard treatment for Stage IIB-IVA cancer of the cervix
Cervical Cancer - DNA testing for HPV complicates management of atypical cervical cytology
Cervical Cancer - Hong Kong diva's death inspires Singapore women to screen for cervical cancer
Cervical Cancer - Role of injectable progesterones in cervical cancer remains unconfirmed
Cervical Cancer - System for cervical cytology reporting is updated
Cervical Cancer Screening - Self-sampling and direct sampling for HPV compared
Chemotherapy - Helsinn signs licensing agreement for palonosetron with Japanese firm
Child Protection - Utah legislators to make parents' rights an 'emotional' issue
Acute Myocardial Infarction - Scientists to study use of fat-derived regenerative cells for treating heart attack
Children's Health Insurance - Connecticut plan would drop kids from state insurance
Children's Health Insurance - Florida lawmakers haggle over funding care for uninsured children
Chiropractic Coverage - Insurers, chiropractic association meet to improve relations
Chlamydia - New screening programs launched in U.K. to reduce STD incidence
Cholera - First mass cholera vaccination begins
Chronic Liver Disease - Interferon-gamma-inducible protein 10 denotes HCV-linked liver status
Chronic Myeloid Leukemia - Marrow fibrosis indicates therapy failure in chronic myeloid leukemia
Clinical Trials - Patient recruitment company says its panel exceeds 6 million members
Clinical Trials - Proper metrics for clinical trials outlined
Addiction Medicine - Alcohol has a dose-dependent effect on endothelial adhesion molecules
Cloning - Leading researcher says anticloning bill would be a mistake
Coagulation Therapy - Is LAA elimination suitable for atrial fibrillation treatment?
Cochlear Implant - Tuning the noise level optimizes performance of tasks in cochlear implants
Cochlear Implants - Penetrating electrode auditory device successfully implanted
Cognition - Long-term progesterone deficits improve spatial performance in older rats
Collaborations - Agreement signed with Atria Genetics for tissue typing tests
Collaborations - Agreement signed with J&J to validate GPCR targets using aptamers
Collaborations - Alliance focuses on development of nanotechnology-based chemical sensors
Collaborations - Alliance targets development of protein activity profiles
Collaborations - Alliance with Baxter to discover anti-MIF antibody
Systems Biology - Science needs a model of complex living systems, Sorger says
Adolescent Health - New reproductive health program informs girls in Nairobi slums
Collaborations - Biomaterials products, services orders exceed $2M in fourth quarter
Collaborations - Biopharmaceutical company enters joint SARS clinical program with Vanderbilt
Collaborations - Companies join forces to accelerate clinical trial recruitment for drugmakers
Collaborations - Deal signed with Fujisawa to develop AGI-1096 for transplant rejection
Collaborations - Drug discovery partnership to collaborate on cardiovascular therapeutics
Collaborations - Fosrenol licensing agreement expanded with Shire Pharmaceuticals
Collaborations - GPC biotech announces achievement of new milestones
Collaborations - Genedata expands genomics-based drug discovery collaboration
Collaborations - Grant received for drug development; enzyme deal signed
Collaborations - KV Pharmaceutical adds to pipeline via development and marketing agreement
Adolescent Health - Rio's mayor nixes teen birth-control plan
Collaborations - M&H Informatics enters agreement to provide packaging solution
Collaborations - Medco, UnitedHealthcare renew strategic relationship
Collaborations - Metabasis joins forces to develop hepatitis C therapeutic
Collaborations - NIH research agreement signed to develop rapid vaccine production system
Collaborations - New cancer vaccine program launched
Collaborations - NextGen Healthcare added to AccuSoft's customer roster
Collaborations - Partnership with Wyeth to develop therapeutics for neurological disorders
Collaborations - Pharmaceutical company announces research milestone with AstraZeneca
Collaborations - Pharmaceutical company identifies SARS antisense drug candidates
Collaborations - Pharmaceutical firms sign deal to develop drugs for Alzheimer disease
Adolescent Health - Survey finds 8,000 clandestine abortions occur yearly in Burkina Faso capital
Collaborations - Program launched to create whole-genome arrays
Collaborations - Research alliance, licensing agreement targets RNA interference
Collaborations - Systems biology company to develop hematology model for Johnson & Johnson
Colon Cancer - Eloxatin approved in U.S. for treatment of metastatic colorectal cancer
Colon Cancer - Larger colon tumors need more injected dye to identify sentinel lymph nodes
Colon Cleaning - Phase II study to begin on new purgative product
Colorectal Cancer - Aggrus expression is frequently upregulated in colorectal tumors
Colorectal Cancer - BRAF mutations associated with sporadic colorectal cancers
Colorectal Cancer - Beta-catenin has a role in invasion and metastasis of colorectal carcinomas
Adolescent Health - Teen abortion, pregnancy rates declining in Washington state
Colorectal Cancer - Clinical trials use gene therapy for GI cancer
Colorectal Cancer - Increased fiber intake is associated with a smaller risk of colorectal adenomas
Colorectal Cancer - Tumor-related Rac1b not regulated by Rho-GDP dissociation inhibitors
Complementary and Alternative Medicine - Aromatherapy offers plant-based nurturing and soul soothing
Complementary and Alternative Medicine - CAM treatments could hinder cancer treatment
Conference Announcement - Medicare drug legislation among emerging issues at healthcare law conference
Constipation - Second phase II trial initiated for opioid-induced constipation treatment
Aging - Getting older tied to lower self-esteem
Constipation - Second phase III efficacy study for constipation treatment completed
Consumer-Driven Healthcare - Blue Cross launches new plan for small-group employers
Contraception - Large clinical trial launched to test "male Pill" in 14 European centers
Contraception - Low-dose levonorgestrel is an effective emergency contraceptive
Contraception - Virginia university resumes distribution of emergency 'morning after' pill
Cord Blood - Singapore to ask mothers to donate cord blood
Coronary Artery Bypass - Veterans' healthcare agency has more care problems than private sector hospitals
Coronary Artery Disease - $1M milestone payment received for initiation of Binodenoson trial
Coronary Artery Disease - Statins prevent AF in chronic stable CAD patients
Airway Dysfunction - Device to improve breathlessness is focus of innovative program
Coronary Bifurcations - CE Mark granted for the Axxess bifurcated stent system
Corporate Update - Biotech device company launches in San Francisco bay area
Corporate Update - Genome5000 program has yielded more than 40 drug discovery programs
Corporate Update - HealthSouth further strengthens corporate governance and compliance practices
Corporate Update - Macrofluidics, microfluidics company changes name
Corporate Update - Oncology drug maker reports initial guidance for 2004
Corporate Update - Significant increase in Levulan Kerastick end-user sales
Corporate Update - Supplement maker discusses progress in refocusing business
Corporate Update - Urological device maker restructures both operating divisions
Correctional Health - Inmates increasing medical bills create budget shortfall
Allergy Drug Trends - Popularity of OTC allergy meds puts prescription drugs under price pressure
Counterfeit Drugs - Millions of fake drugs seized
Courts - Victims of cancer drug dilution scheme to receive checks soon
Cutaneous Lymphoma - Researchers propose guidelines for managing primary cutaneous T-cell lymphomas
Cutaneous Melanoma - p53 Arg/Arg genotype linked to higher risk of cutaneous melanoma over age 50
Cystic Fibrosis - Gene conjugates can be delivered to the airway of fetal sheep in utero
Cytomegalovirus - RNAi program initiated to develop therapies for diseases associated with CMV
DNA Vaccine - Hepatitis delta antigens cause varied immunity in mice
DNA Vaccine - RANK-L gene improves the T cell immune response to infectious agents
Deep-Vein Thrombosis - Study shows DVT preventative treatment not implemented in high-risk patients
Dental - Company gets nod to sell Endopore dental implant in Mainland China
Allergy Medicine - Inactivated split influenza vaccine safe in children with asthma
Depression - Mental illness tied to hypertension by family history
Depression - Nurses can play role in helping cancer patients keep the blues at bay
Depression - Paxil CR receives Canadian approval
Dermatology - FDA clears phototherapy technology developed in Israel
Dermatology - Gene targeting alters keratin 17 expression in murine hair follicles
Dermatology - Inamed acquires license rights to Juvederm
Developmental Biology - Researchers describe cell activity leading to disruption of neuron migration
Diabetes - Overweight Hispanic youth face increased risk of diabetes, metabolic syndrome
Diabetes Complications - Models project links between diabetic retinopathy and kidney disease
Diabetes Pathogenesis - Autoantibodies target beta cell retroviral protein in diabetic mice
Alzheimer Disease - A-beta single chain Fv antibodies isolated from immune phage library
Diabetes Pathogenesis - Co-transfer system in young prediabetic BB rats developed
Diabetes Pathogenesis - IL-18 promotes diabetes development in young nonobese diabetic mice
Diabetes Pathogenesis - Insulin resistance found in offspring of rats using alcohol while pregnant
Diabetes Pathogenesis - Mechanisms of oxidative stress in diabetes reviewed
Diabetes Surgery - Maternal pancreatic islet transplant prevents hypothalamic defect in rat pups
Diabetes Therapy - Transfer of flt-3L-derived dendritic cells delays diabetes development
Diabetic Nephrology - Bosentan protects against diabetic nephrology in diabetic rats
Diabetic Neuropathy - Hyperbaric oxygen is effective adjuvant therapy for diabetic foot ulcers
Diabetic Retinopathy - Gene mutations correlate with proliferative eye disease in diabetes patients
Diagnostics - New method for rapid protein sequence analysis developed
Alzheimer Disease - Gamma Secretase HTS Assay may help further Alzheimer research
Dialysis Catheters - Researchers describe a technique to correct migrated Tenckhoff catheters
Diet and Cancer - Researchers report common and country-specific dietary patterns in Europe
Diet and Nutrition - Chongkukjang improves glucose, lipid levels in diabetic rats
Diet and Nutrition - Maternal diet influences offspring longevity, murine study shows
Diet and Nutrition - Some tomatoes have antithrombotic effects
Dietary Cancer Exposure - Polycyclic aromatic hydrocarbons in foods increase cancer risk
Distribution Agreement - Lifeline to distribute Hexalon bioabsorbable ACL/PLC screw
Drug Abuse - Abuse-resistant form of oxycodone undergoes clinical testing
Drug Approvals - FDA grants approval for generic contraceptive, manic disorder drug
Drug Costs - FDA says U.S. generics a better bargain than many Canadian drugs
Depression - Friendships can help prevent teen suicide
Alzheimer Disease - Gene technique targets memory loss
Drug Development - Antimicrobial agents isolated from Turkish Pimpinella plants
Drug Development - Company signs NIH agreement to develop vaccines
Drug Development - FDA approves generic drug manufacturer based in India
Drug Development - Lavendamycin analogues show promise as antiretroviral agents
Drug Development - Liminoids strongly inhibit HIV protease activity
Drug Development - Pharmaceutical company chooses preferred chemical supplier
Drug Development - Report: FDA will be pressed to do more with less
Drug Development - UMass medicine hunter tracks plants with healing promise
Drug Discovery - Microfluidics firm introduces system to increase analytical HPLC throughput
Drug Discovery - Microplate standards expected to accelerate, streamline industry
Alzheimer Disease - Grants to fund studies of families caring for Alzheimer patients
Drug Discovery - Research collaboration and technology transfer agreement expanded
Drug Resistance - Liposome-based approaches can target drugs to tumor tissue
Drug Resistance - New advance to combat antibiotic-resistant pneumonia and malaria
Education - Agreement to admit HIV-positive children into Nairobi's public schools approved
Elastomeric Medical Devices - Device master file submitted to FDA for absorbable elastomeric biomaterial
Electronic Medical Records - Electronic health records system proposed to improve healthcare
Employer-sponsored Health Insurance - Business leaders meet with senator's staff on healthcare pools
Employer-sponsored Health Insurance - Lawmaker says North Dakota Legislature should reconsider employee benefits
Employer-sponsored Health Insurance - Small business groups have mixed feelings about association health proposal
Employer-sponsored Health Insurance - West Virginia businesses on board with new health plan
Alzheimer Disease - Namenda now available nationwide
End-of-Life Care - Arizona bill would create online medical-directive registry
End-of-Life Care - Psychologists can be helpful for end-of-life decisions
End-of-Life Care - Study: Most Nebraskans wish to die at home; few do
Endocrinology - Endocrine factors underlie bone disease in cirrhotic men and women
Endocrinology - High estrogen levels may make the brain more vulnerable to stress
Endocrinology - Race has little impact on adrenal hormone response to submaximal exercise
Endometrial Cancer - Surgical staging directs appropriate use of radiotherapy
Enterococcus - Glycopeptide-resistant Enterococcus faecium found in ICU
Environmental Health - Method for dual measurement of urinary bisphenol A and alkylphenols developed
Environmental Health - Study: Agent Orange linked to cancer risk
Alzheimer Disease - Pittsburgh Compound B gives unique view of amyloid plaques in living human brain
Enzymology - Lack of matrix metalloproteinase-9 ensures faulty bone formation
Enzymology - Non-apoptotic functions of caspase-3 in nervous tissue reviewed
Enzymology - RhoA stimulates signals conductive to endothelial cell invasion
Ephedra - Methods of addressing potential risks associated with ephedra use reviewed
Epidemiology - Hepatitis B virus pre-S mutants flourish in countries with HBV endemicity
Epidemiology - Prevalence of mental, physical disorders varies within U.S. black population
Epilepsy - Expanded indication for Lamictal offers additional treatment options
Epilepsy - Rights to epilepsy drug, DP-VPA, reacquired from Shire
Escherichia Coli - Expression of N-formylated proteins in E. coli described
Evolutionary Biology - Oxygen triggered the evolution of complex life forms
Alzheimer Disease - Potential tool would aid diagnostic and therapeutic research
Fabry Disease - Biopharmaceutical company to ceases to seek U.S. approval of Replagal
Facilities - Global Life Sciences acquires property in Berlin, Germany
Fatty Liver Disease - The etiology of liver steatosis is often virus-related
Fecal Incontinence - Published trial data demonstrates safety and efficacy of Secca procedure
Fertility Risk - Family faces risks in birth of sextuplets
Fertility Services - IntegraMed America announces new contract
Finance - $135M credit facility positions ResCare for growth in 2004
Finance - Benemax's global insurance pool reduces benefit costs
Finance - Biopharmaceutical company concludes $30M second round of financing
Finance - Biotech company reports strong revenue growth for fourth quarter and 2003
Alzheimer Disease - Researchers begin unique study of brain's tangles
Finance - Biotechnology company closes on initial round of seed funding
Finance - Blood pressure company raises $5 million of additional capital
Finance - Blood safety products company announces $6.6 million private placement
Finance - Company completes sale of therapeutic plasma business
Finance - Company proposes increase in number of authorized common shares
Finance - CompuMed maker announces a 1-for-3 reverse stock split
Finance - Device company reports $0.02 per share loss
Finance - Diagnostics company announces closing of private offering
Finance - Diagnostics company reports loss of $0.12 per share
Finance - Endoscope maker announces fourth quarter 2003 revenues of $12.5 million
Alzheimer Disease - Two proteins may help prevent brain plaques
Finance - Genetics company announces $2.15M private placement
Finance - Genomic-marker company completes $5.4 million series A financing
Finance - Horizon Health Corp. announces first-quarter results
Finance - LCA-Vision provides 2004 guidance; expects increase over 2003
Finance - Life sciences fund closes year with $211M commitment
Finance - Medical device company sees fourth quarter sales increase of 15%
Finance - Medical device maker increases revenue, earnings guidance for 2003
Finance - Medical device maker reports 3Q earnings per share of $0.13
Finance - Metabolic-focused company raises $4M in second close of private financing
Finance - Molecular regeneration company raises $18.875 million in series B financing
Amyotrophic Lateral Sclerosis - AEOL 10150 clears toxicology hurdle; company makes initial draw on financing
Finance - Nanoparticle drug developer reports loss of $0.12 per share
Finance - Nanotechnology developer secures $5M in second-round venture capital financing
Finance - Ophthalmic laser company reports record fourth quarter
Finance - Orders for heparin-coated cardiopulmonary products generate $250,000
Finance - Period extended for acquisition of up to 20% of device company's shares
Finance - Pharmaceutical companies reinvest 10% of revenues to extend product lines
Finance - Pharmaceutical company announces $15M financing, deal with Intel
Finance - Pharmaceutical company announces closing of $50M round C financing
Finance - Pharmaceutical company gets listing on the Frankfurt Stock Exchange
Finance - Pharmaceutical company launches third venture capital fund
Aneurysm - Study confirms good results of coil treatment for aneurysms
Finance - Pharmaceutical company raises $14 million in private offering
Finance - Pharmaceutical company raises $3.7 million in private placement
Finance - Pharmaceutical company raises $41 million in series B financing
Finance - Pharmaceutical company retires over 46% of outstanding common stock warrants
Finance - Pharmaceutical company secures $12M under new management
Finance - Research organization reports 33% increase in operating income
Finance - Veronate maker completes $20 million private placement
Financial Planning - AHA selects Kaufman Hall to provide financial planning tools, services
Fitness - Record number of people ran marathons in 2003
Food-borne Illness - Main bacteria contributing to histamine formation in seafood identified
Angiogenesis - Patent granted for antiangiogenic treatments using VEGF inhibition
Food-borne Illness - Results from viral monitoring of oysters in polluted estuary reported
Food-borne Illness - Rugged LC-MS/MS survey analysis developed for acrylamide in foods
Food-borne Illness - Vitamin E may be key to listeria-free turkeys
Foot Ulcers - Initial dosing complete in phase I chronic diabetic neuropathic foot ulcer trial
Gastric Cancer - A PI3K inhibitor holds promise as an antitumor agent for gastric carcinoma
Gastroenterology - Effects of CDX2 on ileal bile acid-binding protein promoter outlined
Gastroenterology - Gemcitabine halts ascites formation in patients with pancreatic cancer
Gastroenterology - Thymidylate synthase antisense blocks the oncogenic properties of colon cancer
Gene Delivery - PPE-EA attains sustained gene expression in the central nervous system
Gene Expression - Company announces six human genomes on a single BeadChip
Geriatrics - Combined analysis identifies elderly women who are at risk for hip fracture
Animal Models - Diets with different levels of soy affect toxicity assessments in rats
Gene Expression - Gene-disabling technique simplified by medical school team
Gene Expression - Roche to license Eberwine linear RNA amplification technologies
Gene Mapping - Oxford joins HapMap project
Gene Therapy - HIV vector T-cell transduction efficiency is not pseudotype-dependent
Gene Therapy - Phase I/II HIV gene therapy trial initiated
Generics - Innovative Cos. announces first generic drug; human version in pipeline
Genetic Disorders - Malays with distal renal tubular acidosis have high rate of SE Asian ovalocytosis
Genetic Engineering - California county to vote on banning genetically engineered plants, animals
Genetic Research - Asians could benefit from education about genetic research
Genetic Research - Transgenomic to distribute NanoChip Molecular Biology Workstation
Anthrax - Contract signed with Pentagon to supply vaccine
Genital Herpes - Healthy women volunteers sought for final trial phase of herpes vaccine
Genomics and Genetics - Genetic interaction controls intestine length in PRM/Alf mice
Genotyping - Reagent, software product launched for use with genetic analyzers
Geriatrics - The relationship between gender and well-being among older people is complex
Germ-Cell Tumors - Genetic, environmental factors evaluated in germ-cell cancer of three brothers
Gerontology - Vasomotor function loss in elderly linked to eNOS phosphorylation
Glaucoma - Company reports updates in glaucoma, arthritis trials
Global Health - To tackle poverty: Empower women and educate girls, U.N. leader says
Glucose Testing - Florida Medicaid selects provider of monitoring system
Gynecologic Oncology - CYP1A1 polymorphism unrelated to gynecological malignancies in the Japanese
Anthrax - Small-molecule inhibitors of anthrax lethal factor identified
Gynecologic Oncology - New surgical blood ordering system is efficient and saves money
Gynecology - Gynecological practice must include continuing education in relational roles
HIPAA - 90 Days after deadline, payers rejecting more physician claims
HIV Diagnosis - Prototype of a portable detector for protein diagnosis developed
HIV Transmission - Jury finds Iowa City man guilty of criminal transmission of HIV
HIV Treatment - New drug class may enable body's immune system to halt HIV infection
HIV/AIDS - HIV identification bill moves through committee
HIV/AIDS - India's Catholic Church issues guidelines for treating HIV/AIDS
HIV/AIDS Cancer - Low B-cell counts linked to heightened Kaposi sarcoma risk
HIV/AIDS Cancer - Serum preferable to plasma for KSHV load testing
Antibiotic Testing - Pharmaceutical company begins phase I clinical trial of inhaled doripenem
HIV/AIDS Coinfection - Liver transplantation feasible in HIV/HCV-coinfected patients
HIV/AIDS Dementia - PMG augments glutamate output from infected macrophages
HIV/AIDS Enzymology - Yeast system facilitates study of HIV integrase
HIV/AIDS Immunology - Role of CD40L dysregulation in HIV-related APC impairment reviewed
HIV/AIDS Opportunistic Infection - C. albicans cell wall adhesin identified
HIV/AIDS Opportunistic Infection - Molecular assay enables noninvasive PCP monitoring
HIV/AIDS Opportunistic Infection - Oral CMV therapy cost effective
HIV/AIDS Pathogenesis - HIV Nef activates macrophage STAT3 via soluble factors
HIV/AIDS Pathogenesis - Macrophages and lymphocytes have differential effects on anti-HIV RANTES activity
HIV/AIDS Pathogenesis - Nuclear transport of HIV integrase characterized
Anticancer Therapy - Recent developments in antitumor taxoids reviewed
HIV/AIDS Pathogenesis - Opioid-regulated lymphocyte genes identified
HIV/AIDS Pathogenesis - PKA signaling underlies gp120-induced T-cell anergy
HIV/AIDS Pathogenesis - Role of dendritic cell C-type lectin receptors in HIV pathogenesis reviewed
HIV/AIDS Pathogenesis - Serum SDF-1 inactivated during HIV infection
HIV/AIDS Prevention - Incorporating HIV prevention into the medical care of persons living with HIV
HIV/AIDS Proteomics - Nuclear targeting of HIV Rev transport signals clarified
HIV/AIDS Risk Factor - Transmission risk data lacking in HIV/AIDS surveillance system
HIV/AIDS Therapy - Phototherapy ameliorates nanobacteria-related peripheral neuropathy
HIV/AIDS Therapy - STAT1 blockade shows promise for clearance of latent HIV reservoirs
HIV/AIDS Therapy - Treatment-induced recovery of HIV-specific immunity more extensive in children
Antioxidants - Curcumin has properties known to shutter diabetes complications
HIV/AIDS Therapy - Viral AAC resistance mutations identified
HIV/AIDS Tuberculosis - MDR-TB common for HIV patients in Peruvian hospitals
HIV/AIDS Vaccine - Multispecific mucosal cytotoxic T cells fail to control SIVmac239
Head Injury - "Ding" concussions require removal from the game
Head and Neck Cancer - Audiotaped patient consultations are used to survey patient attitudes
Health Funding - Public health spending drops as anti-terrorism funds soar
Health Management - Mutual of Omaha chooses American Healthways for disease management
Healthcare Access - AIDS activists hail victory as U.S. drug company relinquishes patent
Healthcare Access - Foundation helps expand care for uninsured, low-income Massachusetts residents
Healthcare Access - Poor AIDS patients forced to make life-and-death choices
Antisense Technology - Antisense oligonucleotides depend on reliable delivery for therapeutic success
Healthcare Access - Survey says nation's healthcare system is ill
Healthcare Benefits - BCBS proposes options to reduce number of uninsured
Healthcare Benefits - Idaho counties receive $1 billion in healthcare fusion through state agency
Healthcare Benefits - Indonesia proposes plan to provide free insurance to its poor
Healthcare Benefits - More funds approved to expand benefits for Michigan's uninsured
Healthcare Benefits - North Dakota groups work to improve reach of public health insurance
Healthcare Branding - Highmark Blue Shield's HealthGuard now carries the "Blue" brand
Healthcare Economics - AP poll reveals Americans' top concerns; healthcare moves up the list
Healthcare Economics - Iowa officials say budget cuts could destroy long-standing program for poor
Healthcare Economics - Marylanders' healthcare spending was up 11% in 2002
Arthroplasty - Elbow replacements are effective for the rheumatic elbow joint
Healthcare Economics - Police working longer due to health insurance costs in retirement
Healthcare Economics - Vermont's governor proposes health spending initiatives
Healthcare Funding - Budget plans for space exploration instead of health, education questioned
Healthcare Reform - First steps in New Mexico plan controversial
Healthcare Reform - Kennedy proposes major federal expansion for U.S. healthcare
Healthcare Reform - Minnesota lawmakers aim to improve the system
Healthcare and Politics - Presidential candidate Clark would lift stem cell restrictions
Heart Attack - Carvedilol enhances mitochondrial function during myocardial ischemia
Heart Attack - NHE-1 blockade ameliorates postinfarction remodeling
Heart Attack - NIH grant awarded to study the use of adipose-derived regenerative cells
Heart Attack - National training agreement signed for defibrillator use
Heart Disease - Data shows hospital ER use for heart problems increases on snow days
Heart Disease - Registry demonstrates positive outcomes after heart valve implantation
Heart Disease Therapy - Rosuvastatin cost-effective for U.K. National Health Service
Heart Failure Therapy - Carvedilol may be superior to metoprolol tartrate
Heart Transplantation - Tolerogenic mechanisms of LF15-0195 characterized
Hematologic Disease - Platelet membrane glycoprotein mutations do not affect VWD severity
Hematology - Effects of gamma radiation on hemoglobin characterized
Hematology - Intracellular signal inhibitors block H2 O2 -induced platelet aggregation
Assisted Reproduction - Analysis shows babies conceived via ART face high risk at birth
Hematology - Lamivudine prevents HBV flare in leukemia patients treated with campath-1H
Hepatitis A Vaccine - Two-dose hepatitis A vaccine effective in Thai children
Hepatitis B Virus - CHO cell clones expressing hepatitis B surface protein screened
Hepatitis B Virus - Hepatitis B infection appears to trigger adult-onset Still disease
Hepatitis B Virus - Preliminary testing of hepatitis B test kit meets expectations
Hepatitis C Therapy - Hepatitis vaccine collaboration signed
Hepatitis C Therapy - Phase I trials of Actilon initiated
Hepatitis C Virus - Company announces development of two new molecules to battle virus
Hepatitis E Vaccine - HEV-neutralizing antibodies recognize antigen of ORF2 protein vaccine
Hepatology - Alcohol dehydrogenase 6 and apolipoprotein E constructs propel liver transgenes
Psycho-Oncology - Psycho-oncology now has a recognized role within the oncologic community
Assisted Reproduction - Trial begins in lawsuit over embryo pregnancy
Hereditary Angioedema - Positive phase II study results with Icatibant
Hodgkin Lymphoma - Increased serum levels IL-9 may contribute to Hodgkin lymphoma development
Human Papillomavirus - Vaccines for cervical cancer reviewed
Human Papillomavirus - Women's Health Connecticut adopts DNAwithPap test
Huntington Disease - Abnormalities develop early in R6/2 Huntington disease transgenic mice
Huntington Disease - Different phenotype found in monozygotic twins with Huntington disease
Hypertension - B-type natriuretic peptide levels have limited value for diastolic HF diagnosis
Hypertension - Genomic influence of angiotensin II elucidated
Hypertension - Glucocorticoids act in dorsal hindbrain to increase arterial pressure
Asthma - Asthma drug program licensed from Abbott Laboratories
Hypertension - Melatonin may have an effect on nocturnal blood pressure
Hysterectomy - Hysterectomy may not result in impaired sexual arousal
Idiopathic Myelofibrosis - Thalidomide yields success in patients treated for idiopathic myelofibrosis
Imaging - Ultrasound-guided liposomes boost imaging, target drug/gene therapy
Immune Reconstitution - Phase I trial of CYT 99 007 initiated
Immunology - Effects of TCR activation on naive cord blood T cells characterized
Immunology - Fat cells fight disease
Immunology - Hepatitis C virus NS4 uses subversive tactics to thwart Th1 response
Asthma - Controlled-release treatment for asthma and COPD to be developed
Immunology - Pathway for cell-associated antigens by dendritic cells characterized
Immunology - Peripheral blood should be used for flow cytometry T-cell counts
Immunology - Researchers retract part of paper on source of HIV defense
Immunology - Roles of TLR2 and -4 in antimycobacterial host defense characterized
Immunology - Soluble TLR2 isoforms present in plasma, breast milk
Immunology - Soluble adhesion factor marks microvascular changes in arthritis patients
Immunology - To avoid detection, HIV disrupts immune cell migration
Immunology - Viral interleukin-10 gene transfer suppresses genes upregulated by inflammation
Industry Certification - Device manufacturer achieves ISO quality system standard
Infection - Patent granted for nonlive FluINsure vaccine
Asthma - Disappointing phase IIa clinical trial results reported for oral asthma drug
Infection Control - Current hospital infection control methods merit updates
Inflammatory Bowel Disease - Depression may affect bowel disease relapse
Inflammatory Bowel Disease - Phase I trial of Traficet-EN initiated
Inflammatory Bowel Disease - Plantain extract may be future treatment
Inflammatory Diseases - Small molecule collaboration extended
Inflammatory Response - Interleukin-18-binding protein staunches inflammatory response in mouse livers
Influenza - Flu continues to decline; just five states now reporting widespread illness
Influenza - Flu shots last winter not perceived as effective prevention, surveys show
Influenza - Flu shots questioned in study of healthcare workers
Influenza - FluMist to be donated to public health agencies
Asthma - Doubling of steroids before severe asthma attacks ineffective
Information Technology - Anthem supplies tools to help members choose hospitals, prepare for treatments
Information Technology - Baylor Health Care selects DocuData to implement medical record digitization
Information Technology - CMS strengthens initiatives with clinical evidence-based criteria
Information Technology - Catholic Medical Center uses ibex PulseCheck ED system
Information Technology - Children's Hospital Boston, Cerner to deliver pediatric research to clinicians
Information Technology - Company launches S-PLUS validation and clinical reporting solutions
Information Technology - Company launches enhanced Drug Information Framework
Information Technology - Computer resources help doctors answer patient care questions
Information Technology - Computerized records surmount a medical emergency
Information Technology - Duke University Health System selects mobile computing infrastructure
Asthma - Pregnant smokers put babies at increased risk for asthma
Information Technology - Hoag Memorial selects Premier's Clinical Advisor
Information Technology - Horizon BCBS, AdvancePCS begin recruiting for electronic prescribing program
Information Technology - Hospitals choose picture archiving and communications system
Information Technology - Program helps improve ED patient throughput, documentation
Information Technology - Software helps Oklahoma heart hospital to securely install PCs in patient rooms
Information Technology - WellPoint jumpstarts physician participation in electronic medical community
Kidney Dialysis - Advanced glycation end product role in uremia and dialysis outlined
Kidney Stones - Project initiated for biodegradable stents in ureteral, prostate applications
Kinetic Research - Short rest periods stimulate some bone formation in active female mice
Laboratory Tests - LabOne to provide testing for Anthem Blue Cross and Blue Shield
Avian Flu - U.N. FAO seriously concerned about spread of avian flu in East Asia
Language - Monkey calls light language centers
Laparoscopic Nephrectomy - Hand-assisted laparoscopy reduces operative time and improves outcomes
Laryngeal Cancer - Angiotensin-converting enzyme might be a marker for laryngeal cancer
Leg Ulcers - Researchers discuss wound bed preparation for treating venous leg ulcers
Legal Issues - Colorado lawmakers want to head off barrage of fast food lawsuits
Legal Issues - Court to decide: Should murderer of pregnant mom be prosecuted for fetus' death?
Legal Issues - Florida court rules that fetuses can't have guardians
Legal Issues - HealthSouth sees 2004 revenue of $4 billion, says fraud at least $3.8 billion
Legal Issues - Husband plans court challenge in wife's cesarean delivery case
Legal Issues - Intuitive Surgical settles pending litigation
Avian Influenza - Bird flu vaccine not likely for 6 months
Legal Issues - Law firms, hospital agree to change website name
Legal Issues - Makers of OxyContin made unsubstantiated claims, report says
Legal Issues - Malpractice suit for botched appendectomy settled
Legal Issues - Oregon man files lawsuit against ephedra manufacturer, marketer
Legal Issues - R.J. Reynolds tries to overturn $15 million tobacco liability award
Legal Issues - Seven charged with diverting healthcare funds to campaign fund
Legal Issues - Sports doctors settle Medicare fraud suit for $2.6 million
Legal Issues - Switzerland investigators say two dozen patients murdered by male nurse
Legal Issues - Texas commission seeks to move Medicaid case to federal court
Legionnaires Disease - Type I secretion system in Legionella pneumophila described
Avian Influenza - Bird flu's rapidly changing genetic makeup likely behind its rapid spread
Legislation and Prevention - Bill proposed to prosecute those who spread HIV
Leprosy - Genetic underpinnings described
Leptin Studies - Leptin may play direct role in bone metabolism
Leptin Studies - Leptin overexpression decreases basal lipolysis, PKA activity, and perilipin
Leukemia - Adaphostin can damage both myeloid and lymphoid leukemia cells
Leukemia - Dosing commenced in trial of Clofarabine first line treatment
Leukemia - Hematopoietic reserve in B-cell CLL evaluated
Leukemia - High spontaneous colony growth in CMML predicts short survival
Leukemia - Rare combination of genes cause leukemia
Leukemia - Resistance to different classes of chemo agents indicates a poor outcome in ALL
Avian Influenza - Threat to humans is significant
Leukemia - SIN lentivectors can transfer the CD40L gene to leukemia precursor cells
Leukemia - Somatic mitochondrial DNA mutations are associated with adult-onset leukemia
Leukemia - TP53 is frequently altered in acute lymphoblastic leukemia
Leukemia Therapy - Dendritic cell recovery slow after allo-SCT
Leukemia Therapy - Filgrastim stem-cell mobilization safe and effective during imatinib treatment
Licensing Trends - Study looks at maximizing in-licensing opportunities in leading organizations
Limb Ischemia - Treatment for critical limb ischemia submitted to FDA
Lipid Studies - Intramyocellular lipid levels decrease during aerobic exercise
Lipid Studies - Lycopene enhances lipid accumulation in macrophages
Smoking Cessation - Cutting down on cigarettes promotes quitting, Yale study said
Avian Influenza - Vietnam last on vaccine list
Lipid Studies - Mice lacking ARID transcription factor Mrf-2 resist weight gain
Lipid Studies - Thiazolidinediones effective for dyslipidemia in type 2 diabetic patients
Liver Cancer - Antisense suppression of DDEFL1 blocks hepatocellular carcinoma cell growth
Liver Cancer - P-glycoprotein may have a role in liver cancer development
Liver Cancer - Preoperative transcatheter arterial chemoembolization may limit tumor recurrence
Liver Carcinoma - Osteopontin enhances metastatic behavior in hepatocellular cancer cells
Long-Term Care - Groups say national debate needed to set course for senior care
Long-Term Care - Hawaii lawmakers back to square one on tax-funded insurance program
Lung Cancer - Endostatin prevails in nonmalignant and malignant pleural effusions
Lung Cancer - Gemcitabine and vinorelbine combination has a high response rate in NSCLC
Avian Influenza - WHO says SARS helped Asia on bird flu
Lung Cancer - Hypermethylation of p16 in sputum and plasma may indicate lung cancer
Lung Cancer - Welding fumes cause lung impairment, including cancer
Lymphoma Therapy - Stem-cell transplantation is only known cure for CTCL
Malaria - Scientists accuse international agencies of approving useless malaria programs
Malaria Enzymology - Crystal structure of P. falciparum FabZ characterized
Malaria Proteomics - Expression of functional plasmodial fp2 in E. coli achieved
Malaria Therapy - Effects of PKC on artemisinin-induced leukemia cell differentiation clarified
Malaria Therapy - Trends in antimalarial drug deployment in sub-Saharan Africa reported
Market Analysis - "Flanking generics" enables drug makers to retain market share
Avian Influenza - WHO suggests quarantine for bird flu
Market Analysis - Big pharma, biotech look to combinatorial chemistry for future pipelines
Market Analysis - Drug companies spend 46% of marketing budgets on product launch
Market Analysis - Drug discovery spending declining in face of changing market dynamics
Market Analysis - Hesitancy to adopt new technologies restrains dressings market
Market Analysis - OTC switching could be a reality for statins
Marketing Agreements - ICU Medical announces amendments to Abbott agreement
Medicaid - Louisiana plan protects workers counting on Medicaid
Medicaid - Medicaid cuts would stop services to 84,000 Georgians
Medicaid - Montana begins new, 3-year, disease management program
Medical Devices - Transoesophageal echocardiography valuable during non-cardiac surgery
Bacterial Viruses - Bacteriophage genomics method to antimicrobial drug discovery published
Medical Error - Legal papers claim New York hospital gave child fatal mix of painkillers
Medical Errors - South Dakota neurosurgeon, already on probation, faces additional lawsuits
Medical Errors - Young cancer patient's family announces plans to sue Johns Hopkins
Medical Malpractice - Analysis shows premiums lower in states with caps on damage awards
Medical Malpractice - Demonstrators in Utah protest mandatory arbitration
Medical Malpractice - Doctors, victims in Maryland gather as debate heats up
Medical Malpractice - Families sue hospitals that employed a nurse charged with overdosing patients
Medical Malpractice - Follow-up audit in South Carolina finds changes to compensation fund
Medical Malpractice - Group says CBO study fails to consider full impact of rising liability costs
Medical Malpractice - Judge orders information on malpractice lawsuit data
Bacteriology - Accuracy of six systems for Vibrionaceae identification compared
Medical Malpractice - Kentucky's Senate passes malpractice amendment by minimum margin
Medical Malpractice - Minnesota ER doctors say they're facing insurance crisis
Medical Malpractice - New Jersey Democrats vow to address liability insurance, caps
Medical Malpractice - Pennsylvania lawmakers hope third time is charm for malpractice tort reform
Medicare - AHCA faults skilled-nursing facility recommendations again
Medicare - Discount card to emerge from new retail pharmacy, benefit manager alliance
Medicare - Drugstore chains seek discount card
Medicare - Organization's support for legislation leads at least 45,000 members to quit
Medication Compliance - 40% of American adults report difficulty in swallowing pills
Melanoma - Canvaxin therapeutic polyvalent vaccine shows promise against melanoma
Bacteriology - DNA damage recognized by Escherichia coli Fpg protein
Melanoma Vaccine - Allogeneic melanoma tumor cell lysate vaccine benefits patients
Melanoma Vaccine - Melanoma vaccines evaluated by monitoring of tumor-specific T cells
Memory - Scientists discover protein in brain affects learning and memory
Meningitis - Echovirus type 13 emerging as prominent enterovirus
Menopause - Clinical trial data reported for first, oral, plant-derived conjugated estrogen
Menopause - Mobility range holds implications for quality of life in women with osteoporosis
Menopause - Tail-temperatures of estrogen-deficient rats simulate menopausal hot flushes
Mental Health - National study indicates obesity is linked to major depression
Mental Health - State offers help to better identify Creutzfeldt-Jakob, other brain diseases
Mental Illness - Bill would aid children with mental illness
Bacteriology - Mycobacterial consumption of carbon monoxide, hydrogen reported
Mergers and Acquisitions - Acquisition enhances financial services firm's healthcare practice offerings
Mergers and Acquisitions - FTC closes review of Novazyme acquisition
Mergers and Acquisitions - IPVoice to acquire Medical Office Software
Mergers and Acquisitions - Invacare Corp. acquires the assets of ACS
Mergers and Acquisitions - KaloBios, therapeutics company, announce merger
Mergers and Acquisitions - Kimberly-Clark wound care assets acquired
Mergers and Acquisitions - NADAG and SiREEN merge to form drug discovery/development company
Mergers and Acquisitions - Pain relief company completes acquisition
Metabolism - Japanese men but not women carry gene polymorphisms for bone loss
Metastasis - New research technique may help scientists understand tumor spread
Bacteriology - Neutrophil activation regulates Forkhead transcription factors
Metastasis - Simple microbes give insight into the development and spread of cancer
Middle Ear Infection - Patient trials to begin with middle ear infection treatment
Minority Health - Racial, social events can impact healthcare of African American male homosexuals
Mitosis - Phase II trial launched for SB-715992
Molecular Biotechnology - Company acquires technology from Fraunhofer Center
Mosquito-borne Disease - Use of recombinant bacteria for mosquito control reviewed
Multiple Sclerosis - Collaboration to develop multiple sclerosis drug candidates
Multiple Sclerosis - Collaborative research initiative aims for new drugs in half the time
Multiple Sclerosis - Neurological disease not as progressive or disabling as once thought
Mutagenesis - Gene modification increases yields of a yeast used for astaxanthin production
Mutagenesis - Keratin polypeptide gene deletions heighten susceptibility to liver injury
Mycobacteria - Analysis of mycobacterial rpoB gene suitable for RGM identification
Mycobacteria - Clinical management of Mycobacterium fortuitum skin infection outlined
Mycobacteria - IFN-gamma autoantibodies can increase susceptibility to mycobacterial infection
Mycology - Antigens shared by Aspergillus and Penicillium species identified
Narcolepsy - Phase III trials on schedule for R-modafinil; NDA to be filed in 4Q
Nasopharyngeal Cancer - TSLC1 gene is one of the target tumor suppressor genes of nasopharyngeal cancer
Nerve Damage - Scientists reveal key part of nerve regeneration mechanism
Neurodegenerative Disorders - Bioscientists to lead research into brain diseases
Neuroendocrine Tumors - Study shows in vivo phosphorylation of the somatostatin 2A receptor in vivo
Basal Cell Carcinoma - Cancer treatment gets mixed review
Neurology - Alpha V beta 8 integrin is Schwann cell receptor for fibrin
Neuroscience - A new hybrid promoter enhances neuron-specific transgene expression
Neuroscience - Angiogenic growth factor could be used for the treatment of neonatal stroke
Neuroscience - Elevated GDNF levels increase nerve cell death after ischemic stroke in rats
Nutrition - Children at higher risk for hunger if mother has poor mental or physical health
Nutrition - Experimental product boosts immune function and reduces flu symptoms in elderly
Nutrition - One-size-fits-all approach to nutrition recommendations may soon be outdated
Nutrition - Schools asked to aid in ending junk food craze; implementing healthy diets
Nutrition - Utah students may get longer lunch periods
Obesity - CDC: Obesity costs states billions in medical expenses
Women's Health - Greater patient-doctor dialogue may improve a women's healthcare
Baylisascaris - Baylisascaris procyonis found in metropolitan Atlanta area
Obesity - Physical fitness, nutrition are hot topics for West Virginia coalition
Obesity - U.S. Surgeon General calls obesity "the terror within"
Obesity Genomics & Genetics - -308 Nco I polymorphism of TNF-alpha does not affect weight loss
Obesity Genomics & Genetics - Analysis of obesity in diabetes confirms loci on chromosomes 1q and 11q
Obesity Genomics & Genetics - SLC6A14 gene linked to obesity
Obesity Prevention - Governments back WHO's anti-obesity plan
Obesity Surgery - Laparoscopic adjustable gastric banding effective for massive superobesity
Obesity Surgery - Massachusetts probing death of man following obesity surgery
Obstetrics - Combined prenatal exposure to second-hand smoke, urban air pollutants harmful
Obstetrics - Fertility experts' group strengthens commitment to reducing multiple births
Biosample Archiving - BioServices division wins contract to establish NIDDK biosample repository
Obstetrics - Researchers identify enzyme that helps make uterus stretchy
Obstetrics - Study calls for end to age thresholds for prenatal genetic testing
Occupational Health - The face and eyes provide a means for occupational acquisition of hepatitis C
Oncogenesis - Beta3Gal-T5 counteracts malignancy-related glycosylation in cancer cells
Oncology - A switch to the lymphangiogenic phenotype typifies CIN stage 3 cervical lesions
Oncology - Combined gene regulatory elements select for melanoma suicide gene expression
Oncology - Genes noted for aggressive phenotypes can be found within malignant melanoma
Oncology - Hepatitis B virus X protein is involved in the etiology of liver cancer
Oncology - Interleukins-1 alpha and beta have differential effects on tumorigenicity
Oncology - Thalidomide prolongs disease stabilization in those with recurrent glioblastoma
Biosensors - Artificial membranes can reveal biological weapons
Oncology - Viral gene therapy shows promise for treating sarcoma
Oral Health - Gene therapy in salivary glands could lead to promising applications in oral diseases
Oral Implants - Alveolar distraction can increase the height of the alveolar ridge
Oral Implants - Early loading of endosseous implants is 95.6% successful at 1-year
Oral Implants - Study compares direct digital and conventional intraoral radiography
Orbit Tumors - Definitive surgery is the goal for orbital schwannomas and neurofibromas
Organ Transplant - Grants to fund new organ transportation devices and cryopreservation methods
Osteoarthritis - Study confirms efficacy of Lyprinol in treating osteoarthritis
Osteoporosis - Angiogenic cytokine modulates bone remodeling in steroid-treated animal models
Osteoporosis - Folate has a strong link to bone mineral density in postmenopausal women
Bipolar Disorder - FDA approves Zyprexa to delay relapse into mania, depression
Osteoporosis - Microarchitectural changes explain the benefits of antiresorptive therapy
Osteoporosis - New phase III study shows positive results for oral monthly Boniva
Osteoporosis - Oral bone forming drug candidate acquired
Osteoporosis - Selenium, vitamin E, and vitamin C combinations prevent bone decline
Outbreaks - Vibrio cholerae outbreak linked use of chlorinated water source
Ovarian Cancer - Data: Drug candidate MPI-176716 causes ovarian tumor remission
Ovarian Cancer - Fact/GOG-Ntx questionnaire offers valid assessment of neuropathy
Ovarian Cancer - Researchers study non-epithelial ovarian cancer in Mexican women
Oxygen Monitoring - Brigham and Women's Hospital implements SET oximetry hospital-wide
PET Imaging - Neuroimaging company inks agreement with GlaxoSmithKline
Bipolar Mania - FDA grants approval for Seroquel
Pain Management - Pain treatment decisions may be influenced by physician gender
Pain Management - Third-party billing program available for ambulatory surgery centers
Pain Medicine - FDA launches consumer campaign on safe use of OTC pain products
Pain Medicine - High bone mineral density associates with low back pain in middle-aged women
Palliative Care - Groups provide $300,000 grant to fund fellowships
Panic Disorder - Emotion-regulating protein lacking in panic patients
Parasitology - 14-3-3 Protein is key molecule in parasites as in other organisms
Parkinson Disease - Down-regulation of DJ-1 enhances cell death
Parkinson Disease - Parkin is recruited to centrosome in response to proteasome inhibition
Patents - Geron receives favorable ruling in nuclear transfer patent interference matter
Birth Defects - Ohio begins work on registry to track birth defects
Patents - MRI contrast agent patent strengthens company's proprietary position
Patents - Patent granted for treatment of psoriasis
Patents - Pharmaceutical company is issued U.S. patent for cancer therapy
Patient Education - Better info could help American Indians/Alaska Natives receive recommended care
Patient Education - Heart patients want more information from their doctors
Pediatric Cardiology - Fusion of technologies improves infant survival rates after heart surgery
Pediatrics - Development of rational therapeutics in children reviewed
Perception - Study shows that senses are tied to movement
Peri-Implant Bone Loss - Gelatinase B is associated with peri-implant bone loss
Periodontal Disease - Blood test may reveal factors that relate to gum disease, especially in men
Bladder Cancer - Smoking plus drinking water with arsenic increases risk of bladder cancer
Peripheral Arterial Disease - Diabetics are urged to check legs
Personnel - Aviel Faliks, PhD, majority stock holder, becomes new CEO
Personnel - Batkin joins board of directors at infection control device company
Personnel - Biopharmaceutical company names new vice president, clinical affairs
Personnel - Biotech company names senior VP, general counsel, secretary
Personnel - Biotechnology company appoints new chairman of the board of directors
Personnel - Blose named board director at microarray company
Personnel - Chip maker names executive to head new clinical diagnostics division
Personnel - Dennis M. Keane named CEO of CNS-focused pharmaceutical
Personnel - Drug discovery company names Frank Karbe CFO
Blood Transfusion - Prosecutors proceed cautiously with stabbing victim who refused transfusion
Personnel - Drug-eluting stent maker reports 15% increase in sales
Personnel - Five Star announces election of new director
Personnel - Former HIAA executive named URAC senior VP of planning and operations
Personnel - Gastroenterological expert joins board of nutraceutical company
Personnel - Genetic assessment company announces a change in board of directors
Personnel - Genomics company announces two new appointments
Personnel - Gregory S. Ballish named vice president of sales and marketing
Personnel - HMS strengthens leadership team, prepares for future growth
Personnel - Healthcare staffing company names CEO
Personnel - Healthcare veteran Patrick G. LePore joins board
Bloodstream Infections - Once-weekly Dalbavancin shows superiority for bloodstream infections in study
Personnel - Imaging company names Dennis Mulroy CFO
Personnel - John C. Parmigiani joins QuickCompliance as senior VP for consulting services
Personnel - John Hamer named VP of drug delivery company
Personnel - Kevin S. Moore named to board of neurological device company
Personnel - Kristina M. Johnson, PhD, elected to board of directors
Personnel - M. Renee Simar, director of pediatrics, becomes VP
Personnel - MacDonald named president, COO at biotech company
Personnel - Magnus Precht named president of Phyton, Inc.
Personnel - McCarthy joins IT firm as senior scientist, clinical consultant
Personnel - McGuire named chief medical officer at gene therapy company
Bone Cancer - Orthopedic implant designed to restore function
Personnel - Medical device company announces management succession
Personnel - Medical product manufacturer names new chief technology officer
Personnel - Medical products company appoints interim chief executive officer
Personnel - Nancy Larkin joins Courage Center as vice president of healthcare development
Personnel - New director appointed for Mississippi Medicaid program
Personnel - Osagie Imasogie named to board of directors of biotech company
Personnel - Pharmaceutical company adds two new board members
Personnel - Pharmaceutical company announces new member of board of directors
Personnel - Pharmaceutical company announces retirement of co-founder and CEO
Personnel - Pharmaceutical company appoints Theresa Bischoff to board of directors
AIDS - Man accused of falsely telling woman he gave her AIDS
Bone Density - Some bone sites in the humerus may provide stronger fixation for implants
Personnel - Pharmaceutical company names two new vice presidents
Personnel - President James T. Lenehan retires
Personnel - Robinson joins board of biotech company
Personnel - Swartz promoted to VP, controller at device firm
Personnel - Vogel named to biotech company's board of directors
Personnel - Winger named to board of directors
Peutz-Jeghers Syndrome - Antibiotics related to geldanamycin could promote development of carcinoma
Pharmaceutical Care - McKesson renews agreement with Omnicare
Pharmacy Management - Jackson Memorial selects Cardinal Health for pharmacy management services
Pineal Region Tumors - Researchers describe a new tumor forceps for removal of pineal region tumors
Bone Fractures - Bone graft clinical trial initiated at lead U.S. site
Pituitary Tumors - Researchers discuss mechanisms for pituitary tumorigenesis
Poliomyelitis - Nigerian state upholds ban on polio vaccinations
Poliomyelitis - WHO considers rapid response to halt polio spread in Africa
Postoperative Ileus - Results reported in Entereg phase III study
Practice Management - Orthopedic practice selects outsourced practice systems management solution
Prenatal Medicine - Prenatal diagnosis impacts the parental psyche
Prescription Benefits Management - Bills introduced in Michigan Legislature to lower drug costs
Prescription Benefits Management - Contract renewal has firm continuing to provide pharma distribution services
Prescription Drug Abuse - Petition requests FDA to require risk management plans for OxyContin generics
Prescription Drug Benefits - Program helps Louisiana seniors save on purchases
Bone Grafts - Endoskeleton structural device for the spine issued FDA 510k clearance
Prescription Drug Benefits - Program shows informed consumers decide to save on medication
Prescription Drug Importation - FDA scrutinizing county's plan to bring in drugs from Canada
Prescription Drug Importation - Iowa governor seeks HHS authorization for pilot program
Preventive Healthcare - Georgia hospital wins $100,000 prize for work in building coalitions
Prion Disease - Improved method for detecting PrPc in peripheral nerves developed
Prion Diseases - Physicists study mad cow-type diseases
Privacy Issues - Britain to end egg, sperm donor anonymity
Product Safety - U.S. regulators uphold ban on silicone gel breast implants to market
Prostate Cancer - Elderly men need more education about prostate-specific antigen screening
Prostate Cancer - Maximum tumor diameter is a predictor of tumor volume
Bone Grafts - Further studies of transplanted composite bone grafts-implants are needed
Prostate Cancer - Pan-European marketing partner named for prostate cancer products
Prostate Cancer - Provenge extends survival in advanced prostate cancer
Prostate Cancer - TRPS1 may play a role in androgen regulation of PSA gene expression
Protein Competition - Shifting protein signals allow VEGF receptor-1 to flourish on adult cells
Protein Synthesis - Scientists describe new strategy to make glycoproteins
Proteomics - Embryonic handedness in C. elegans involves G alpha protein
Proteomics - Novel member of protein phosphatase 2C family cloned
Proteomics - OX-43 deficits mark the invasive phenotype of endothelial cells
Proteomics - Structure and regulation of Che-1, a novel partner of Rb, reported
Proteomics - Thioredoxin stamps out microvascular endothelial capillary tubule formation
Bone Grafts - Vitoss bone graft material receives FDA clearance
Psychosomatic Medicine - Century of research confirms impact of psychosocial factors on health
Public Health - Study: Health gap between blacks and whites in Chicago widening
Public Health Practice - Viral hepatitis rates in Lower Saxony reflect common disease risk factors
Pulmonary Medicine - CRP testing cannot exclude pulmonary embolism
Quality Assurance - Hospital star ratings in U.K. are misleading the public, report says
RNA Research - Techniques for study of ribonucleoparticle complexes reviewed
Rabies Vaccine - DNA vaccine more effective against rabies than culture-derived vaccine
Rabies Virus - Novel lyssaviruses isolated from bats in Russia
Radiation Exposure - New study finds no link between cancer and cell phone use; more research needed
Radiopharmaceuticals - Company enters into $3 million supply agreement for oxygen-18
Bone Loss - Spinal and radial analyses are best for determining bone health
Rat Brain Tumors - Arsenic trioxide enhances radiation response of 9L glioma in the rat brain
Receptor Studies - Interaction of vasopressin analogs with vasopressin receptors modeled
Receptor Studies - Neutral histamine H-1-receptor antagonists synthesized
Receptor Studies - Structural organization of receptor associated protein characterized
Reconstructive Surgery - Osteocutaneous flap prefabrication preserves bone viability in rabbits
Rectal Cancer - Tumor treatment blocks blood vessels
Reducing Risk - 2004 cancer report card for California a mixed bag
Referrals - Florida HealthSource adds more than 25 providers to network
Regulatory Approval - Diagnostics company gets CE mark certification
Regulatory Issues - FDA implements broader requirements for tissue bank registration
Bone Marrow Transplant - Researchers discover secret for recalling stem cells
Regulatory Issues - FDA sees rebound in approval of innovative drugs in 2003
Regulatory Issues - FDA takes actions against illegal drug import operations
Regulatory Issues - Guidant CRM division deploys EDC and eResearch Community solutions
Regulatory Issues - Medical sanctions on rise in West Virginia
Regulatory Issues - Pennsylvania insurance agency orders Blues to justify large cash reserves
Renal Cell Cancer - Interim clinical results of GTI-2040 in combination chemotherapy announced
Reovirus - Histidines needed for reovirus guanylyltransferase activity identified
Reproductive Health - Experts examine Europe's population, health, and social concerns
Reproductive Medicine - Neurotrophin receptors are critical to female germ-cell survival
Research Technology - Computer application "reads" medical literature, finds significant data
Bone Repair - Angiogenic factors increase during distraction osteogenesis
Respiratory Distress - Kappa B may initiate respiratory distress in the septic surgical patient
Respiratory Therapy - Collaboration announces initiation of human trials for respiratory indication
Rheumatoid Arthritis - Does RA-related inflammation induce cardiovascular disease?
Rheumatology - Intravital fluorescence microscopy assesses angiogenesis in arthritic mice
Rheumatology - Osteoarthritis and pain constrict hand function in postmenopausal women
Robotics - Robotic mitral valve surgery reviewed
Rotavirus - Virulence region of rotaviral nonstructural protein NSP4 characterized
SARS - Flu season helps U.S. prepare for SARS
SARS - Real-time PCR enables rapid diagnosis
SARS - WHO finds evidence that animals play SARS role
Bone Tumors - Endoprosthetic extremity reconstruction in children can be successful
Salivary Duct Carcinoma - Salivary tumor features in 15 patients described
Salmonella - Salmonella enterica isolated from humans and food animals characterized
Schistosomiasis - IL-10 regulates immune responses induced by schistosome vaccine
Schizophrenia - Common genetic influence found in mental illnesses
Seborrheic Dermatitis - Results reported from phase III studies of Sebazole
Sexually Transmitted Disease - Many men would rather cope with STDs than use condoms, study finds
Sinus Surgery - Sinus lift surgery is safe for regenerating the atrophic posterior maxilla
Sleep Apnea - Upper airway EMG responses to acute hypoxia impaired in diabetic rats
Smallpox - Smallpox vaccines to be delivered to CDC
Smoking - Inmate smoking ban moves ahead in California
Bone Tumors - Free vascularized fibular graft is an option for limb-sparing surgery
Smoking Cessation - Shopping-voucher system rewards quitters instantly
Social Attachments - Reward mechanism involved in addiction likely regulates pair bonds
Spinal Cord Injury - Scientists grow neurons using nanostructures
Spine Surgery - New anesthetic techniques for spinal surgery in adults are discussed
Staffing - Rural doctors in western Kentucky await reinforcements
Staffing - West Virginia nursing overtime bill still alive
State Medicaid - Budget proposal for New York could include higher rates for program recipients
State Medicaid - Medicaid losses in Michigan painful for some adults
Stem Cells - Human embryo stem cells produced in Japan
Stem-Cell Research - Bcl-xL-transduced stem cells provide better bone marrow transplantation
AIDS - Media organizations unite to fight HIV/AIDS
Bone Tumors - Rotationplasty is useful for tumors with a large soft-tissue component
Stem-Cell Research - CD41 expression defines hematopoiesis onset in murine embryo
Stem-Cell Research - Effects of NF-kappaB/Rel on leukemic cell apoptosis reviewed
Stem-Cell Research - Embryonic stem cell-derived glial precursors show promise for transplantation
Stem-Cell Research - IL-21 triggers rapid maturation of natural killer cell precursors
Stem-Cell Research - MEK-1/ERK signal effects on erythroid progenitor self-renewal clarified
Stem-Cell Research - Matrigel-based cultures promote neuronal differentiation of mesenchymal stem cells
Stem-Cell Research - Novel model of hematopoietic cancer cell kinetics proposed
Stem-Cell Research - STI571 inhibits mast cell development in vitro
Stem-Cell Research - Serum hepatocyte growth factor rises during stem cell mobilization
Stem-Cell Research - Ultraviolet light facilitates better transduction of bone marrow stem cells
Bone Tumors - Surgical role in treating primary malignant bone tumors under debate
Stem-Cell Transplantation - Risedronate prevents bone loss in allo-SCT survivors
Stock Market - Nutrition bioscience company faces possible NASDAQ delisting
Streptococcus - Enolase from Streptococcus sobrinus is immunosuppressive protein
Streptococcus - Researchers map pneumococcal surface protein A of strain Rx1
Stress - Grant funds stress reduction program for women cancer patients
Stress - Unemployment strikes a harder blow on men's mental health
Stroke - Anticlotting drug may be better than aspirin in preventing third stroke or heart attack
Stroke - Burden of plaque is lower in women than men
Stroke - Professional groups review best treatment and management of ischemic stroke
Stroke - Rising cholesterol levels in Asia may increase stroke risk
Bone Tumors - Telecommunication and telepathology optimizes treatment of malignant bone tumors
Subdural Hematoma - CO2 insufflation for chronic subdural hematoma helps recovery
Suicide - Suicide prevention, education services available in Washington county
Supply Chain Management - Medwave updates on progress for purchasing agreement
Surgical Infections - New system rapidly identifies patients with nasal colonization of S. aureus
TB Prevention - Plans underway to launch U.S. study of tuberculosis vaccine
TB Prevention - WHO launches program to curb TB/HIV co-infection
Telemedicine - Product gives patients access to pediatric specialty care without the drive
Testicular Cancer - Combination chemo offers high cure rates for most metastatic testicular cancer
Thyroid Cancer - Change of urinary glucocorticoids level may play a role in thyroid cancer
Tobacco Settlement - Counties want money for ill nursing home patients
Botulinum Toxin - Hemagglutinin element of toxin from Clostridium botulinum identified
Tobacco Settlement - Smoker's widow awarded $20 million in damages
Toxicology - A new in vitro assay tests earlier for toxic effects during oogenesis
Transfusion Medicine - Better treatment of porcine RBCs needed before human transfusion is feasible
Transgene Expression - Radiolabeled FIAU monitors the progress of cancer gene therapy
Transplant Medicine - Adult live-donor liver transplants resume at New York City hospital
Transplant Medicine - Drug prevents diabetes recurrence after islet cell transplantation
Transplant Medicine - Hospital resumes adult live-donor liver transplants 2 years after donor's death
Transplant Medicine - Issues related to donor altruism examined
Tuberculosis - Epidemiology of extrapulmonary TB in San Francisco clarified
Tuberculosis - Oklahoma seeks court order to keep TB patient isolated
Bovine Spongiform Encephalopathy - Premortum test for mad cow disease under development
Tuberculosis Animal Models - Lung cell responses in genetically resistant mice clarified
Tuberculosis Diagnostics - TaqMan PCR assay enables rapid mycobacteria counts
Tuberculosis Enzymology - Crystal structure of M. tuberculosis PPAT characterized
Tuberculosis Epidemiology - Genetic distance useful as measure of ongoing TB transmission
Tuberculosis Epidemiology - Size of TB clusters not linked to symptom duration
Tuberculosis Immunology - CD57+ CD4 cells play key role in host defense against TB
Tuberculosis Immunology - HLA class I-restricted CD8 cells help control TB infection
Tuberculosis Pathogenesis - CD44 expression affects type but not efficacy of anti-TB immune response
Tuberculosis Therapy - Isoniazid toxicity characterized
Tularemia - PCR assay for enhanced detection of Francisella tularensis developed
Brain Disorders - Program addresses disabling neurological, mental illness in developing world
Tumor Ablation - Radiosurgery company gets Japanese regulatory clearance for CyberKnife
Tumor Marker - Silenced MAT-8 genes make prostate cancer cell proliferation decline
Tumor Suppression - Heterozygous disruption of the beclin 1 autophagy gene promotes tumorigenesis
Ultrasound - Three-dimensional ultrasound technology available in Houston, Texas, area
Urethral Cancer - Report reviews the treatment of urethral cancer
Urinary Incontinence - Materials used for pubovaginal slings remain strong in rodent studies
Urinary Tract Infection - Scientists film bacteria changing, collaborating to defeat bladder cell defenses
Urinary Tract Infection - Video details how bacteria invade and overwhelm bladder cells
Urology - Bladder screening device approved in U.S.
Vaccine Delivery - Bacterial spores as heat stable vaccine vehicles reviewed
Brain Tumors - No environmental, chemical link found in Rohm and Haas brain tumor cases
Vaccine Safety - Infant develops Kawasaki disease after hepatitis B vaccination
Vaccines - Plant-based vaccines to be developed by Dow
Vector Development - Electroporation facilitates gene transfer into adult skeletal muscle myofibers
Vector Development - Magnetofection is a useful tool for transfecting endothelial cells
Vector Development - Vaccine adjuvant vector, CTA1-DD/ISCOM, designed
Vectors - One dose of "designer" gene therapy may target specific body area
Vectors and Zoonoses - Anopheles funestus dinucleotide microsatellite markers identified
Vegetarian Diet - All-vegetable vitamin E pill introduced
Venous Bypass Grafting - Stent implantation better than balloon angioplasty in de novo saphenous vein graft
Veterans Affairs - Group is suing Veterans Affairs' secretary over "rationing" of healthcare services
Breast Cancer - Areola-sparing mastectomy with immediate reconstruction is feasible
Veterans Affairs - Tennessee men no longer have to give up smoking for Viagra
Viral Genomics - The INNO-LiPA HBV identifies mixed genotypes in difficult samples
Virology - Borna disease virus infection reported in immunocompromised patients
Virology - Recombinant constructs revive p53 tumor-suppressor activity in tumor cells
Virology - Scientists create chip that detects viruses quickly
Virology - Several genetic loci are known to regulate adenovirus-based gene therapy
Vulva Reconstruction - Modified VRAM flap can resurface a large vulvoperitoneal defect
Vulvar Pathology - Laser Doppler perfusion imaging can map vulva microcirculation
Weight Gain - Adolescents tend to gain excessive weight during pregnancy
Weight Loss - Dieting for weight loss decreases memory ability
Breast Cancer - CAD workstation reference library to aid in early breast cancer detection
Weight Loss - Ephedra alternatives reviewed
West Nile Virus - CDC: 2003 West Nile outbreak largest yet
Workers Compensation - Senator goes after compensation for Cold War-era nuclear workers
Wound Care - New dressing developed
Wound Healing - Mitogenic protein in latex from Carica candamarcensis identified
Wound Healing - Wound healing may be accelerated with a traditional scalpel blade
Wound Repair - Angiotensin peptides accelerate wound healing in diabetic mice
X-Ray Technology - SuperSpeedSolutions launched for materials research, nanostructure applications
Breast Cancer - FDA grants clearance to market Ariol HerSight
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