Susan Hasty, Publisher
Table of Contents . . . March 8th, 2004
Non-Subscriber - Summaries OnlyRelated Areas: Other Issues in Health and Medicine Week | Other Publications
Myocardial Infarction - Growth factor boosts heart cell production in damaged hearts
Complementary and Alternative Medicine - Ginkgo biloba extracts could be an alternative to hormone replacement therapy
Hypoxia - Project demonstrates inherited ability to adapt to life at high altitudes
Pediatric Obesity - National campaign to get kids physically active is working
AIDS Therapy - Data presented on potential new class of antiretroviral therapy
Abortion - Ramosetron prevents nausea and vomiting associated with pregnancy termination
Acne - Laser therapy prevents acne from graduating to scars
Acromegaly - Growth hormone disorder puts patients at risk for CAD, diabetes, hypertension
Acromegaly - Surgery leads to biochemical remission of acromegaly in 55% of patients
Acute Myeloid Leukemia - PCR asay aids Aspergillus endocarditis diagnosis in AML patients
Addiction Medicine - Publication addresses compulsive gambling
Addiction Medicine - Study uncovers how stress and hormones lead to smoking relapse
Adverse Drug Effects - In utero exposure to NSAIDS sometimes leads to neonatal renal failure
Age-Related Macular Degeneration - The macular pigment Raman detector assesses carotenoid status in the retina
Alcohol Abuse - Five million parents have alcohol problems, federal report says
Alcoholism - Better methods needed to treat people with both mental health, alcohol-use problems
Alcoholism - Brief interventions work best for problem drinking among young people
Alcoholism - Genetics may determine response to alcohol, subsequent behavior
Alcoholism - Proteomics may be able to help identify and treat alcohol's effects on the body
Allergy - Children with fever before age 1 less likely to develop allergies
Allergy - Contact dermatitis on face could be caused by variety of allergens
Alzheimer Disease - Broad patent granted for neurologic gene therapy
Alzheimer Disease - Cathepsin B identified as important in mediating nerve cell death
Alzheimer Disease - Cholesterol implicated in the development of Alzheimer disease
Alzheimer Disease - New study may explain how fats damage neurons
Alzheimer Disease - Possible mechanism for link between diabetes and AD discovered
Alzheimer Disease - Researchers describe how AD meds may reduce interference with learning, memory
Alzheimer Disease - Survey finds gaps in public's knowledge of treatments for AD
Amyloidosis - FDA grants fast track approval for Fibrillex
Amyotrophic Lateral Sclerosis - Metabolomics company awarded biomarker study collaboration
Amyotrophic Lateral Sclerosis - RNA interference represses mutated SOD1 genes in mammalian cells
Anastamosis - Multiple anastomoses may reduce risk of thrombosis in free-flap transfer
Anesthesia - FDA issues clearance of next generation anesthesia monitor
Anesthesia - Skin permeation device facilitates rapid skin anesthesia within 5 minutes
Ankle Fractures - Less-invasive surgery shows promise for foot and ankle fractures
Anthrax - B. anthracis spores can germinate, grow and reproduce in soil
Anthrax - Surface layer protein EA1 is not component of Bacillus anthracis spores
Anti-Infectives - Artemisinin alkylates human hemoglobin A0
Antiangiogenesis - THAM-derived cotelomers bearing thalidomide units stop new vessel growth
Antibiotics - Solid-phase synthesis of cyclic decapeptide antibiotic streptocidins reported
Antisense Technology - New lipophilic cation conjugates direct antisense agents to the inner cell
Anxiety - In-silico anxiety drug to undergo phase I clinical trials
Anxiety - Many Americans still upset, fearful after 9-11 attacks
Apoptosis - Sepsis drug also protects brain cells
Assisted Reproduction - Genetic screening counseling should be offered to infertility patients
Assisted Reproduction - Religion guides views of fertility treatment in Middle East
Assisted Reproduction - Surrogate mother legislation passes Oklahoma House committee
Asthma - Children's flu vaccination does not relieve exacerbations
Asthma - New diagnostic test developed
Asthma - One in five asthmatics highly sensitive to aspirin
Asthma - Survey finds many women stop or reduce asthma drugs during pregnancy
Atopic Dermatitis - Antisense molecules delivered by iontophoresis improves skin lesions in mice
Atopic Dermatitis - Infants exposed to dogs have reduced risk of developing atopic dermatitis
Atrial Fibrillation - U.K. facing costly "epidemic" of heart pump disturbance
Automated External Defibrillators - External defibrillators move into retailing via Walgreens online
Avian Influenza - Bird flu not going away soon, WHO says
Avian Influenza - Expert warns bird flu outbreak could evolve into SARS-like epidemic
Avian Influenza - Infection-control company launches fight against avian flu
Avian Influenza - Leopard reportedly dies of bird flu; study of patients shows short incubation period
Avian Influenza - New approach may provide prompt recovery from bird flu
Avian Influenza - New research could lead to potential treatment for avian flu
Avian Influenza - South Asia health officials hold emergency meeting on avian influenza
Avian Influenza - U.S. senators want task force to deal with avian flu
Avian Influenza - Vaccine could be made quickly if Asian bird flu goes global, U.S. officials say
Bacillus - BH1999 protein of Bacillus halodurans C-125 is a thioesterase
Bacillus Calmette-Guerin Vaccine - Intranasal BCG vaccine better than subcutaneous vaccine against pulmonary TB
Bacteriology - Community-acquired pyelonephritis is linked to drug-resistant E. coli
Bioinformatics - Ingenuity's products licensed for drug discovery
Biotechnology - Autologous fibrin glue useful for maxillofacial surgery
Blood Banking - Therapeutic company files five patent infringement lawsuits
Botulinum Toxin - Mouse bioassay and ELISA compared for detecting botulinum toxin in food
Bovine Spongiform Encephalopathy - New form of mad cow disease is discovered
Bovine Spongiform Encephalopathy - Researchers search for new mad cow test
Bovine Spongiform Encephalopathy - Slaughterhouse owners dispute USDA "downer" claims of its mad cow
Brain Cancer - Mouse brain cancer is monitored longitudinally with MRI
Brain Cancer - New scan could predict response to brain cancer treatment
Brain Research - Hong Kong, mainland scientists to set up Chinese brain bank
Brain Tumors - Higher spatial resolution of fMRI is needed for neurosurgical planning
Breast Cancer - Breast cancer risk significantly reduced in association with soy intake
Breast Cancer - Breast surgeons' group to lead MammoSite RTS patient registry
Breast Cancer - Community screening trials provide new answers about early detection
Breast Cancer - Deregulated EZH2 gene may be related to poorly differentiated breast carcinoma
Breast Cancer - Folate-targeted lipid-based gene vectors reduce breast adenocarcinoma volume
Breast Cancer - Gamma-tocotrienol can induce apoptosis in human breast cancer cells
Breast Cancer - Having an outlet for stress may lower patients' mortality risk
Breast Cancer - Imaging equipment provider broadens mammography product line
Breast Cancer - Invasive micropapillary breast carcinoma demonstrates high vessel density
Breast Cancer - Long-term use of antibiotics possibly linked with increased disease risk
Breast Cancer - Most general surgeons in Canada treat breast disease
Breast Cancer - New breast cancer test introduced
Breast Cancer - Nonattendance at breast cancer screenings may be due to socioeconomic factors
Breast Cancer - Phase III study of RSR13 initiated in women with brain metastases
Breast Cancer - Reproductive history is unrelated to progression to invasive breast cancer
Breast Cancer - Significant disparities still exist in screening mammography rates
Breast Cancer - Study finds nipple-sparing mastectomy is a reasonable option for certain patients
Breast Cancer - Women at high risk of breast cancer pleased with preventive mastectomy decision
Breast Cancer Risk Factor - Adipose PCB increases risk of breast cancer recurrence in women
Business & Finance - Connecticut hospitals still going through financial crunch
Business & Finance - Developing countries seek international system for biodiversity sharing
Business & Finance - Hospital essential to city's health has powerful help in dispute
Business & Finance - Hospital funding debated in Wyoming
Business & Finance - House committee narrowly passes cigarette tax increase
Business & Finance - Medical services tax dropped from bill approved by New Mexico house
Business & Finance - PatientKeeper mobile computing closes 2003 with record fourth quarter
Business & Finance - Pennsylvania hospitals show mixed results on finances
Business & Finance - Pennsylvania state police in favor of proposed law restricting medicine sales
Business & Finance - Pharmaceutical alliances result in greater profits, reports analyst
Business & Finance - Pharmaceutical company signs agreement to promote Riomet
Business & Finance - Private pharmacy companies complain about unfair competition
Business & Finance - Trospium maker reports net loss for first quarter 2004
Business Update - Agreement reached for workers at one of the nation's largest nursing home chains
Business Update - Biotech business donated to Pittsburgh medical center by Rohm and Haas Co.
Business Update - Collaboration provides financial services for consumer-driven healthcare
Business Update - European sales for expanded for oncology sales
Business Update - Hospital's appeal claims plan to build competing facility is illegal
Business Update - Las Vegas selects consumer-driven healthcare program
Business Update - Levulan PDT generates excitement at AAD meeting
Business Update - Mail-order contract from Medco Health taken over
Business Update - Nurse overtime bill passed by West Virginia house
Business Update - Strategic alliance formed to deliver new generation of healthcare
Cancer Diagnosis - Aging hepatitis C virus carriers should undergo screenings for liver cancer
Cancer Metastases - Tumor blood vessels forecast the risk of breast cancer travel to lymph nodes
Cancer Research Award - Pan-Mass Genomic Services grant awarded to help fund cancer research
Cancer Risk - Harvard study says aspirin may lower risk of Hodgkin disease
Cancer Risk - Large study to assess vitamin use and cancer risk
Cancer Suppression - Forced expression of connexin 26 arrests the growth of prostate cancer cells
Cancer Therapy - Amidox inhibits ribonucleotide reductase in human leukemia cells
Cancer Therapy - Clinical study to investigate the combination of GTI-2040 and gemcitabine
Cancer Therapy - Company announces publication of gambogic acid research
Cancer Therapy - Docetaxel may be an effective alternative to taxane in ovarian cancer
Cancer Therapy - Gutless vectors encoding transgenes enhance the effect of oncolytic viruses
Cancer Therapy - Norwegian Radium Hospital receive FUGE grant to develop new anticancer agents
Cancer Therapy - Novel triaryl methane derivatives fight cancer without injuring the liver
Cancer Therapy - Salvinal has antimitotic activity in drug-resistant human tumor cells
Cancer Therapy - Scientists overpower cancer's drug defenses
Cancer Therapy - Three Thai medicinal plants show toxicity to certain tumors in vitro
Cancer Therapy - Vascular targeting agent technology reviewed in medical journal
Cancer Therapy - p53 Gene transfer won't harm normal cells
Cancer Vaccine - Electrofusion of dendritic cells and tumor generates therapeutic vaccine
Cardiac Ischemia - New marker linked with heart disease in women
Cardiology - High heart rate reduces arterial distensibility
Cardiology - Modulation of potassium channels is dependent on protein tyrosine kinase
Cardiovascular Disease - APOA5 locus strongly influences plasma triglyceride levels in ethnic groups
Cardiovascular Disease - MTHFR mutation raises pediatric hyperhomocysteinemia risk
Cardiovascular Disease - Angiotensin II causes oxidative stress in hypertension patients
Cardiovascular Disease - Cardiac troponin I mutation linked to idiopathic dilated cardiomyopathy
Cardiovascular Disease - Effect of APOE gene variants on European life expectancy clarified
Cardiovascular Disease - Heart resynchronization can resolve pacemaker-induced mitral regurgitation
Cardiovascular Disease - Hypertension-induced cardiac remodeling reviewed
Cardiovascular Disease - Lower blood pressure credited for reduced CVD mortality in Israel
Cardiovascular Disease - Paraoxonase pharmacogenetics reviewed
Cardiovascular Disease - Post-revascularization contractile recovery in LV dysfunction patients evaluated
Cardiovascular Disease - Stem-cell transplantation can prevent lysosomal storage disease-induced CVD
Cardiovascular Disease Diagnostics - Biomarkers of acute coronary artery disease reviewed
Cardiovascular Disease Diagnostics - Hand-held ultrasound valuable for field CVD diagnosis
Cataract Surgery - A new technique for cataract surgery does not use preoperative eye drops
Cataracts - CollAm intraocular lens can be implanted during active uveitis
Catheter-Related Infections - U.S. Food and Drug Administration approves clinical trial for MethLock
Cell Biology - Chemical that turns mouse stem cells into heart muscles discovered
Cell Biology - DHEA boosts growth rate of human neural stem cells
Cell Biology - Equine cloning's triple play sheds light on calcium, cell signaling
Cell Biology - Hepatitis C virus relies on cellular proliferation for genomic replication
Cell Biology - Stem cell "ribbon" found in adult human brain
Cervical Cancer - Atypical glandular cells in HPV+ patients may indicate serious disease
Cervical Cancer - Cervical cancer prevention should include human papillomavirus testing
Cervical Cancer - Hycamtin-cisplatin regimen shows cervical cancer survival advantage
Cervical Cancer - Meta-analysis suggests HPV testing helps identify potential cases
Cervical Cancer - Optical detection system with colposcopy improves cervical cancer detection
Cervical Cancer - Overexpression of HER-2/neu uncommon in invasive carcinoma of uterine cervix
Cervical Cancer - Study characterizes gene silencing in precursor to disease
Chagas Disease - Role of chemokine receptors in chagasic cardiomyopathy evaluated
Chemoprevention - Lycopene and carotenoids may slightly reduce the risk of rectal cancer in women
Chickenpox - Effectiveness of vaccine decreases after 1 year
Childhood Cancer - Male fertility must be considered when evaluting treatment for childhood cancer
Childhood Immunization - Parents must get more information to counter immunization fears
Childhood Obesity - Pilot program aimed at preventing obesity in children did not reduce obesity
Childhood Obesity Risk Factor - British children become sedentary at young age
Children's Health Insurance - SCHIP provided health coverage to 5.8 million U.S. children in 2003
Chlamydia - Disease incidence set North Dakota record in 2003
Chocolate - Symposium yields good news for chocolate lovers
Chronic Beryllium Disease - Electrostatics affect antigen recognition in chronic beryllium disease
Chronic Liver Disease - Genome-wide scans could identify genes that present a risk for liver fibrosis
Chronic Myelogenous Leukemia - Lack of cytogenetic response after imatinib treatment predicts relapse
Chronic Obstructive Pulmonary Disease - Daxas submitted for European approval
Chronic Renal Failure - Effects of homocysteine on left ventricular hypertrophy in pediatric CRF clarified
Cloning - Cloned stem cells regenerate heart muscle following a heart attack
Cognitive Function - Fitness can improve thinking among aging
Collaborations - Development, sales, support agreement signed with Applied Biosystems
Collaborations - Emory, partner, identify topical microbicides for drug development
Collaborations - GPC Biotech achieves milestone in osteoarthritis alliance
Collaborations - High-throughput medicinal chemistry deployed in alliance
Collaborations - MDS Pharma Services announces strategic alliance
Collaborations - Manufacturing, business development partner named for m-doc technology
Collaborations - Merck enters alliance to develop and commercialize gaboxadol for sleep disorders
Collaborations - Milestone payment received from licensing agreement with Pfizer
Collaborations - Mouse genetics deal signed to generate mice for gene function analysis studies
Collaborations - Negotiations proceed on deal to formulate new type of aspirin
Collaborations - PET supplier reports renewal of supply, license agreements with Merck
Collaborations - Premier enters contract for supply of medical gases
Collaborations - Research milestone reached in deal with Amgen
Colon Cancer - Gender and location may be related to the pathogenesis of colon cancer
Colon Cancer - Osteopontin correlates with colon cancer tumor progression
Colorectal Cancer - Study shows RAY1/ST7 is not a colorectal cancer tumor suppressor gene
Complementary and Alternative Medicine - FDA approves acupressure wristband for nausea
Complementary and Alternative Medicine - Regulatory issues on safety and efficacy of herbal remedies discussed
Congestive Heart Failure - Nearly half of Americans experience delay in heart failure diagnosis
Congestive Heart Failure - Peptide may help predict heart disease
Congestive Heart Failure - Statin medications may markedly improve survival of heart failure patients
Consumer Information - Kiosk Information Systems and Healthnotes launch consumer health kiosks
Consumer-Driven Health Insurance - Survey: Programs encourage behavior changes that lead to healthier outcomes
Contraception - Bush advocates abstinence-only education
Contraception - Court says company's health benefits must cover prescription birth control
Contraception - FDA postpones morning-after pill decision
Contraception - Survey shows slow start for California's new "pharmacy access" program
Coronary Artery Bypass - Ischemic preconditioning cuts rhythm disturbances after coronary artery bypass
Coronary Artery Bypass - Pulsatile pump preserves platelets better
Coronary Artery Bypass - Simultaneous OPCAB and esophagectomy feasible for esophageal cancer patients
Coronary Atherectomy - A new plaque excision system for complex coronary lesions shows early success
Coronary Heart Disease - Apolipoprotein A phenotypes mark CHD familial aggregation
Cosmetic Surgery - Working party reports on feasibility of facial transplantation
Coughing - Chronic cough significantly impacts life quality in women
Critical Care - Study compares clinical diagnoses and autopsy diagnoses in ICU deaths
Cysticercosis - Taenia solium antigen diagnostic for cysticercosis characterized
Cytomegalovirus Vaccine - Glycoprotein B DNA vaccine prevents congenital cytomegalovirus transmission
DNA Variants - System introduced for DNA sequence variation studies
Dengue Fever - Dengue virus strains show promise for candidate vaccines
Dengue Fever - Factors affecting vector competence of dengue virus mosquitoes studied
Dengue Fever - Live-attenuated dengue virus vaccine stimulates TH1 immune responses
Dengue Fever - Safe and immunogenic monovalent attenuated dengue vaccines developed
Dengue Virus - Dengue virus envelope protein changes structure after membrane fusion
Depression - Can drugs prevent recurrence of depression? The news is depressing
Dermatology - Hair disorders: Dermatologists identify the top causes of tress distress
Developmental Biology - Fat and smart - the perfect combination?
Developmental Biology - Jefferson researchers uncover biochemical clues to how cells migrate in embryos
Diabetes - Limb-saving procedures reduce diabetic foot amputations
Diabetes - People with diabetes warned of increased risk of heart disease, stroke
Diabetes - Young people prone to type 2 diabetes exhibit alterations in mitochondrial activity
Diabetes Genomics and Genetics - Rat Iddm4 mapped to segments on HSA7 and MMU6
Diabetes Management - FDA approves new Guardian Continuous Glucose Monitoring System
Diabetes Pathogenesis - Cross-priming of diabetogenic T cells dissociated from autoantigen shedding
Diabetes Pathogenesis - Leptin, TNF-alpha, and NO affect insulin resistance via different mechanisms
Diabetes Pathogenesis - Troglitazone prevents increased activity of 11-beta-HSD-1 in diabetic islets
Diabetes Risk Factor - Children with history of diabetes have reduced beta-cell function
Diabetes Therapy - Rehmannia glutinosa oligosaccharide is hypoglycemic in diabetic rats
Diabetes Therapy - Beta-carbolines potentiates insulin secretion from islets of Langerhans
Diabetes Therapy - Electronic monitoring can improve diabetes care
Diabetic Nephropathy - Cytomegalovirus ischemic colitis develops in renal transplant recipient
Diabetic Neuropathy - Cases of diabetic cervical radiculopathy with capsulitis of shoulder reported
Diabetic Neuropathy - Glycation end products accumulate in kidney, retina, and peripheral nerve
Diagnostics - A fully automated chemiluminescent microparticle immunoassay counts HBV antigen
Diagnostics - Bile carcinoembryonic antigen can be helpful in diagnosing bile duct cancer
Diagnostics - Blood test could avoid inappropriate use of antibiotics for respiratory infections
Diagnostics - Circulating markers are important in diagnosing neuroendocrine tumors
Diagnostics - FDG PET imaging is optimal for assessing head and neck carcinoma
Diagnostics - Frozen sections cancer diagnosis is quick and reliable for most tumors
Diagnostics - Orofacial pain syndromes can be evaluated by laser stimuli
Diagnostics - Rapid diarrhea test saves lives
Diagnostics - The LCx HCV RNA quantitative assay possesses several key attributes
Diagnostics - The in vivo chamber angiogenesis assay measures angiogenic activity in mice
Diagnostics - [18F]FDG-PET identifies patients ready for reconstructive surgery
Dialysis - FDA clears SpeedLyser infusion catheter
Diet and Nutrition - Amino acid composition of soybean protein affects carbohydrate oxidation
Diet and Nutrition - Breastfeeding longer is beneficial
Diet and Nutrition - Cysteine-containing garlic derivatives have antioxidative activity in mice
Diet and Nutrition - Dietary lignins are precursors of murine lignans
Diet and Nutrition - Fighting hunger today could help prevent obesity tomorrow
Diet and Nutrition - Lifestyle strongly influences immune function during hypercholesterolemia
Diet and Nutrition - Postpartum weight-loss classes work
Disease - Hospital confirms one Norwalk virus case, second hospital suspected
Disease Management - Computerized disease registries offer key to improving chronic disease care
Disease Prevention - Aging CDC labs will be improved with appropriation of $250 million
Disease Prevention - Federal panel recommends increased mad cow testing
Disease Prevention - Medicine may be handled by post office in national emergency
Drug Delivery - ANDA filed for Toprol-XL; generic version of Lotensin launched
Drug Delivery - Aeroneb Go Nebulizer introduced in U.S.
Drug Delivery - Anticompression therapies could open up tumors to anticancer drugs
Drug Delivery - Cell fusion could repair organs, deliver cancer vaccines
Drug Delivery - Company enters R&D agreement to develop a topical gel for treating pain
Drug Delivery - Intracoronary abciximab in coronary stenting may be better than i.v method
Drug Delivery - Study shows effective transdermal delivery of testosterone
Drug Design - Studies offer new insight into HIV vaccine development
Drug Development - Bacillus thuringiensis crystal proteins protect against malaria in mice
Drug Development - Amino acid-conjugated quinolinamines are potent antimalarials
Drug Development - Bicyclam-GalCer agents have disappointing antiretroviral activity
Drug Development - Cyclohexane derivatives strongly inhibit HIV integrase activity
Drug Development - Galactopyranosyl amino alcohols show promise as antimicrobial agents
Drug Development - Novel compounds reveal an ability to stem hepatitis C virus replication
Drug Development - Novel method improves bremazocine enantiomer synthesis
Drug Development - Novel trioxane derivatives have improved antimalarial activity
Drug Development - Water-soluble dipeptide HIV PI prodrugs synthesized
Drug Discovery - Drug discovery and pharmaceutical companies sign research agreement
Drug Discovery - Lab filters earn Zymark/Caliper exclusive certification
Drug Discovery - New, nonradioactive screen for antimalarial compounds developed
Drug Guidelines - Investigation focuses on payments to state agency, officials
Drug Safety - Group joins FDA effort to ensure integrity of drug supply
Drug Settlement - Banner Health Systems settlement money being distributed
Drug Use - New test could help reduce unnecessary antibiotic use
Ebola Virus - Ebola virus-like particles protect from lethal Ebola virus infection
Ebola Virus - Infection with Ebola virus persists under conditions of partial immunity
Ebola Virus - Novel Ebola virus-like particles produced from cDNAs
Encephalitis Vaccine - Nipah virus vaccine provides protection in hamster model
Endocrinology - ACE inhibitors ameliorate connective tissue growth factor-induced retinopathy
Endocrinology - Can early experiences predispose to hormonal disorders later in life?
Endocrinology - Female apolipoprotein E-knockout mice experience early cognitive decline
Endocrinology - Ghrelin promotes adipogenesis directly in vivo
Endocrinology - High neonatal 5HT levels antagonize the masculinizing effects of testosterone
Endocrinology - Phenotypic array of hypothalamic neuronal cell models generated
Endocrinology - Progestins have little impact on how estrogens influence bone health
Endocrinology - Treatment for endocrine disease: Is something missing?
Endometrial Cancer - Estrogen replacement therapy associated with low endometrial cancer recurrence
Endometriosis - Aromatase inhibitor shows therapeutic promise for endometriosis
Endoscopic Ultrasonography - Endoscopic ultrasonography is advancing to guide tissue sampling
Environmental Health - Environmentalists say President Bush, Florida governor are harming water quality
Environmental Toxins - Exposure to low-level magnetic fields causes DNA damage in rat brain cells
Environmental Toxins - High rate of respiratory symptoms seen in police at World Trade Center site
Enzymology - Matrix enzyme polices cellular proliferation by controlling IGF bioavailability
Enzymology - Peptidyl-alpha-ketoamide inhibitors take unusual steps to block HCV protease
Enzymology - Protease inhibitors detected by reverse zymography method
Epicardial Echocardiography - Intraoperative epicardial echocardiography can assess valve function
Epidemiology - Leukemia panel will meet once more in northern Nevada town
Escherichia Coli - GenProtEC provides improved analysis of E. coli K-12 protein functions
Ethics - Bioethicists take differing views on cloning breakthrough
Evolutionary Biology - Researcher offers a new perspective on human evolution
Exercise & Health - Retired gymnasts retain high levels of bone mass during early adulthood
Expansion - MedCath announces opening of 12th hospital
Fabry Disease - Replagal receives Canadian approval to treat Fabry disease
Facial Implants - Zygomatic implants restore function in patients with resorbed maxillae
Fetal Medicine - Fetal mouse brain cells self-destruct when maternal folate levels are deficient
Finance - Albuferon maker reports increased net loss in 2003
Finance - Band-Aid maker reports 40% increase in revenues
Finance - Biomaterials company reports 49% increase in product sales
Finance - Biopharma company to issue $150M of convertible notes in private offering
Finance - Biopharmaceutical company announces initial public offering
Finance - Biopharmaceutical company reports earnings of $1.44 per share
Finance - Bioscience company reports 2003 financial results
Finance - Biotech company reports 19% revenue growth for 2003
Finance - Biotech company reports 2003 and fourth quarter financial results
Finance - Biotech firm completes $2.5M revolving credit, security agreement
Finance - Blood products firm reports repayment of debentures
Finance - CVProfilor maker completes $2.75M equity financing announced in August 2003
Finance - Cancer drug maker reports loss of $0.18 per share
Finance - Cancer-focused biopharma reports second quarter net losses
Finance - Capsule endoscopy company announces record sales, positive cash flow in fourth quarter
Finance - Cardiovascular disease drug maker reports loss of $1.21 per share
Finance - Catalytic antioxidants maker reports net loss in first quarter
Finance - Consumer products company increased gross revenues in first quarter
Finance - Contract research services company reports 26% revenue increase
Finance - Defibrillator maker secures line of credit
Finance - Dental lab company reports increased sales for fourth quarter and full year 2003
Finance - Device company secures new financing, announces expansion
Finance - Device firm reports revenue growth, quarterly earnings
Finance - Device maker reports sales of $2.3M in fourth
Finance - Diagnostic products manufacturer announces positive 2003 financials
Finance - Diagnostics company reports first quarter net losses
Finance - Diagnostics company reports increased revenue in fourth quarter, full year 2003
Finance - Diagnostics company reports strong financial results for Q4 and full year 2003
Finance - Diagnostics maker reports 10.3% decrease in sales
Finance - Diagnostics maker reports 9.5% increase in revenue
Finance - Drug delivery company reports 8.6% decrease in contract revenue
Finance - Drug delivery company's debt upgraded by Moody's
Finance - Federal grant supports advances in infant heart disease
Finance - Gene-variation company reports fourth quarter and year end results for 2003
Finance - Genesis HealthCare Corp. reports first quarter fiscal 2004 results
Finance - Genomics company prices private placement of $100M notes
Finance - Gentiva reports fourth quarter and full year 2003 growth
Finance - Healthcare product supplier to China reports loss of $0.10 per share
Finance - Heath-products company reports positive third quarter earnings
Finance - Hemophilia treatment developer reports yearly loss of $1.28 per share
Finance - Higher revenue, earnings reported by medical device firm
Finance - Immunotherapeutics firm announces $25M in equity financing
Finance - Implant company's 2003 revenues increase by 20% over 2002
Finance - Inflammatory diseases drug maker reports quarterly loss of $0.43 per share
Finance - Laser maker reports 41% increase in fourth quarter 2003 revenues
Finance - Life sciences company raises an additional $1.15 million
Finance - LymphoCide maker reports net loss in second quarter
Finance - Medical device manufacturer announces 2003 financial results
Finance - Medical products manufacturer announces 2003 financial results
Finance - Metabolic/endocrine-focused company reports improved financial results
Finance - Mitsui makes equity investment in proteomics company
Finance - Molina Healthcare reports fourth quarter and year end results
Finance - Neurobiological Technologies receives $2.25M related to Memantine
Finance - Neuroscience company reports net loss of $0.02 per share
Finance - Nutritional supplements developer reports fiscal second quarter results
Finance - Ophthalmic pharmaceutical company announces completion of financing round
Finance - Ophthalmology company receives first round financing
Finance - Oscilloscope maker files registration statement for follow-on public offering
Finance - Pennsylvania biotech greenhouse invests $3M in regional enterprises
Finance - Pharmaceutical company announces 2003 financial results
Finance - Pharmaceutical company board announces stock split
Finance - Pharmaceutical company reports "challenging yet successful" year
Finance - Pharmaceutical company reports 2003 financial results
Finance - Pharmaceutical company reports increased losses, reduced revenues
Finance - Pharmaceutical company reports loss of $0.09 per share
Finance - Pharmaceutical company reports loss of $0.29 per share
Finance - Pharmaceutical firm moves to NASDAQ market under new symbol
Finance - Pregnancy-test maker completes private placement
Finance - Private equity financing to help fund development of KRX-101 and KRX-0401
Finance - Private pharmaceutical company receives $15.3 million in series A financing round
Finance - Product revenues increase 17% for cardiovascular device maker
Finance - Research company reports increased fourth quarter revenues
Finance - Respiratory care products company reports profitable 2Q
Finance - Respiratory-therapy company reports 19% increase in revenues
Finance - Robotics company reports record $27.6 million fourth quarter sales, up 30%
Finance - Sales grow 13.7% for pharmaceutical company
Finance - Senior care firm announces call of $4.5M of its 10% notes
Finance - Ultrasound technology company reports positive financial results for 2003
Fitness - Indoor school activity areas often closed to public
Fitness - Super Bowl ends many gym-goers' drive
Follicular Thyroid Carcinoma - A cell-mediated approach to sFlt-1 gene therapy targets thyroid cancer
Food Safety - Kansas panel endorses bill moving food safety duties to agricultural agency
Food-borne Illness - Yersinia pseudotuberculosis traced to fresh produce for the first time
Food-borne Illness - Effects of handling on biogenic amine formation in fish reported
Food-borne Illness - Putrescine indicates decomposition in penaeid shrimp
Food-borne Illness - World food safety experts offer new methods to assess risk
Gastric Cancer - Computer program helps with planning gastric cancer surgery
Gastroenterology - Helicobacter pylori has been implicated in the formation of liver cancer
Gastroenterology - VEGF might be a predictor of gastric cancer transformation
Gastrointestinal Tumors - Targeted molecular autofluoresence can detect murine intestinal adenomas
Gene Expression - Genetic diseases often caused by mutations in highly expressed genes
Gene Therapy - Scientist warns gene therapy could build superathletes
Gene Transfer - A new gene carrier steers interleukin-12 to solid tumors
Gene Transfer - An autogene-based cytoplasmic expression system improves gene expression
Gene Transfer - Insulin gene nasal inoculations improve diabetes in insulin-dependent models
Generic Drugs - Company announces approval and launch of benazepril hydrochloride tablets
Generic Drugs - FDA approves Benazepril Hydrochloride ANDA
Genetic Disorder - Contraception choices for woman with factor V Leiden outlined
Genital Cancer - Estrogen affects ultrastructure of testis germinal epithelium in Wistar rats
Genomics - A new cis-acting replication element will provide insight into HCV RNA action
Genomics and Genetics - Relation of Msx homeobox gene family and craniofacial development reviewed
Geriatrics - Elderly patients in Taiwan have quality of life changes after hip fracture
Geriatrics - What are your odds of surviving into your hundreds?
Germ Cell Tumors - Temozolomide proves ineffective in cisplatin-refractory germ cell tumors
Gluten Intolerance - Celiac disease may predict schizophrenia
Gynecological Cancer - Image fusion helps resolve discrepant findings between FDG-PET and MRI/CT
HIV Diagnosis - FDA clearances granted for ViroSeq HIV-1 genotyping system
HIV/AIDS - Billions budgeted in South Africa for fight against AIDS
HIV/AIDS - Controversial Nebraska bills would create new HIV-related crimes
HIV/AIDS - Iowa Hospice worker helps African hospice cope with AIDS
HIV/AIDS - Japanese doctor accused in HIV scandal unfit to stand trial
HIV/AIDS - Officials to experience life in Chinese AIDS villages
HIV/AIDS Diagnostics - Real-time SYBR green PCR useful for HIV viremia measurement
HIV/AIDS Drug Resistance - Genotypic resistance after abacavir, efavirenz salvage treatment characterized
HIV/AIDS Education - Grant to support HIV/AIDS education among religious cults in Brazil
HIV/AIDS Epidemiology - For first time since 1992, AIDS cases rise in Los Angeles County
HIV/AIDS Epidemiology - Illinois AIDS cases decline
HIV/AIDS Epidemiology - UN: HIV growth rates in Estonia, Russia and Ukraine among world's fastest
HIV/AIDS Pain - NGX-4010 demonstrates pain reduction in HIV-associated neuropathy study
HIV/AIDS Pathogenesis - Conformation of HIV gp41 during cell entry determined
HIV/AIDS Pathogenesis - HIV-1 trans-activator protein affects pathogenesis of HIV-1 infection
HIV/AIDS Pathogenesis - Immune failure occurs without CD4+ T-cell depletion in SIV-infected macaques
HIV/AIDS Pediatric - Cytotoxic T-cell CD38 expression predicts viral control in HAART-treated children
HIV/AIDS Perinatal Medicine - HIV coreceptor expression determined in exposed but uninfected infants
HIV/AIDS Prevention - Germany launches first HIV/AIDS vaccine trial
HIV/AIDS Proteomics - Effects of P-TEFb on HIV transcription elucidated
HIV/AIDS Proteomics - Entropic switch regulates myristate exposure in HIV matrix protein
HIV/AIDS RNA Research - Perinuclear HIV RNA release mediated by hRIP
HIV/AIDS RNA Research - Retroviral replication system aids HIV TAR study
HIV/AIDS Therapy - Adiponectin attenuates protease inhibitor-induced dyslipidemia
HIV/AIDS Therapy - Adiponectin levels linked to lipodystrophy, stavudine treatment
HIV/AIDS Therapy - CTP biosynthesis inhibitors augment 3TC efficacy
HIV/AIDS Therapy - Drug "cocktail" benefits women with advanced HIV/AIDS
HIV/AIDS Therapy - Efavirenz-induced sleep abnormalities evaluated
HIV/AIDS Therapy - No GPG-NH2 resistance mutations seen in vitro
HIV/AIDS Therapy - Once-daily lopinavir/ritonavir pill evaluated
HIV/AIDS Therapy - Sarcoidosis rate and severity reduced in HAART era
HIV/AIDS Therapy - Significance of residual lymphoid HIV RNA determined
HIV/AIDS Transmission - Heterosexual Hispanics, blacks account for high proportion of cases
HIV/AIDS Treatemnt - Human clinical trials of HIV maturation inhibitor to commence
HIV/AIDS Treatment - New data reported on Serostim treatment in HARS patients
HIV/AIDS Treatment - New data suggest potential for once-daily dosing regimen of Kaletra
HIV/AIDS Treatment - Phase II HIV study results of Reverset announced
HIV/AIDS Tuberculosis - Rifampin strongly reduces indinavir levels
HIV/AIDS Vaccine - Company presents model for a new therapeutic vaccination strategy against HIV
HIV/AIDS Vaccine - Vaginal infection with influenza A elicits immune response to HIV epitope
HIV/AIDS Vertical Transmission - Novel DNA extraction method enables HIV diagnosis via dried blood
HIV/AIDS Woman's Health - GBV-C infection has protective effect in HIV+ mothers
HIV/AIDS Woman's Health - Injected contraceptive use heightens acute HIV viremia
Head and Neck Cancer - Angiogenesis is difficult to quantify in oral cancers
Head and Neck Cancer - The angiogenic switch is an early event in esophageal squamous cell carcinoma
Health Prevention - Defibrillators donated to high schools in South Carolina
Health and Well-Being - New Jersey middle school puts a limit on bathroom breaks
Healthcare Coverage - Almost 1 in 5 South Carolinans have no health coverage
Healthcare Coverage - Catholic hospitals in California adopt policies to protect uninsured patients
Healthcare Coverage - Employee health insurance is looked over by South Dakota lawmakers
Healthcare Coverage - Florida lawmakers shape budget
Healthcare Coverage - Full Medicaid changes put on hold in Vermont
Healthcare Coverage - Health savings accounts: Interest high, knowledge low
Healthcare Coverage - HealthAmerica and HealthAssurance expand hospital network in Pennsylvania
Healthcare Coverage - HealthPartners plans to offer drug discount card for Medicare beneficiaries
Healthcare Coverage - Kentucky governor's health insurance plan draws complaints
Healthcare Coverage - KidCare money among main healthcare issues
Healthcare Coverage - McCoy says Mississippi House budget to fully fund insurance
Healthcare Coverage - Missouri's proposed Medicaid cuts could leave 48,000 without coverage
Healthcare Coverage - Nonprofit housing operator files for bankruptcy
Healthcare Coverage - Shawano County Rural Health Initiative created in Wisconsin
Healthcare Coverage - Ukraine criticizes U.N. decision to suspend funding for HIV/AIDS
Healthcare Economics - Finances, changing needs a challenge for rural hospitals in West Virginia
Healthcare Economics - Poll shows health, retirement costs weigh on Iowans' minds
Healthcare Trends - Report looks at healthcare leaders under pressure
Heart Disease - FDA requests additional information on decellularized heart valves
Heart Disease - Minority women in U.S. unaware of higher risk
Heart Disease Mortality - Cheap, four-drug combo saves heart patients' lives
Heart Disease Risk - For heart disease, efforts that click are better than changes that never stick
Heart Disease Risk - More needs to be done to fight heart disease in young people
Heart Disease Risk - Routine tests, scans not recommended for patients at low risk for heart disease
Heart Disease Therapy - Improved medical treatment of serious heart problems focus of study
Heart Failure - QRS prolongation prevalence in hospitalized HF patients evaluated
Heart Failure - Rate of LV hypertrophy progression to heart failure evaluated
Heart Failure - Rights acquired to a key cardiac marker, NT-proBNP
Heart Failure Therapy - Nesiritide superior to nitroglycerine treatment
Heart Failure Therapy - Superiority of ACE inhibitors remains questionable
Heatstroke - Wearable air-conditioners: Hot, new microtechnology keeps GIs cool
Hematology - Peripheral blood lymphocyte reference for Asian populations developed
Hemodialysis - Dialysate iron therapy for hemodialysis patients receives patent
Hemodialysis Catheter - A new catheter introducer sheath is an improvement but has some problems
Hemophilia Therapy - FVIII gene-carrying SIV vectors show promise
Hepatitis - VIR201 data presented at conference
Hepatitis B Virus - Nabi signs international distribution agreement for Nabi-HB
Hepatitis C Virus - Results reported in landmark study evaluating Ribavirin in HIV/HCV patients
Hepatitis C Virus - Vaccine possible for multiple strains of hepatitis C, evidence shows
Hepatitis E Vaccine - Hepatitis E virus DNA vaccine protected cynomolgus macaques against infection
Hepatocellular Carcinoma - Splenectomy in patients with HCC and secondary hypersplenism can improve staging
Hepatocellular Carcinoma - Surgery for biliary tumor thrombus prolongs survival in hepatocellular cancer
Hepatology - Viral DNA remains in the chronically infected liver despite viral clearance
Herpesvirus - Glycoprotein M need in herpes morphogenesis varies among virus family members
Hodgkin Disease - Modified cytotoxic T cells ferry interleukin-12 to local tumor sites
Hodgkin Lymphoma - Hodgkin lymphoma treatment should focus on improving late morbidity, mortality
Hormone Replacement Therapy - HRT pros, cons should be considered for women with severe menopausal symptoms
Hyperglycemia - Insulin-producing cells found in a variety of tissues in diabetes
Hyperparathyroidism - Some types of familial isolated hyperparathyroidism have unknown cause
Hypertension - Benazepril Hydrochloride Tablets approved for marketing
Hypertension - Black and green tea polyphenols lower blood pressure in rats
Hypertension - Causes of fibrosis in hypertensive heart disease patients reviewed
Hypertension - Company receives final approval on benazepril HCl/HCTZ tablets
Hypertension - FDA plans expedited evaluation of AmVaz NDA
Hypertension - Phase II trial of ALT-711 initiated in endothelial function
Hypertension - Superior blood pressure control reported with use of treatment algorithm
Hypertension - Vasodilation, improved endothelial function underlie effects of quercetin
Idiopathic Dilated Cardiomyopathy - Myocardial perfusion not linked to peripheral endothelial function
Imaging - Medical Media Systems buys tumor-imaging technology
Immunizations - A-Fujian strain tentatively added to influenza vaccine for next year
Immunizations - Committee approves mandatory hepatitis vaccines for Indiana high schools
Immunizations - Short supply of booster shots forcing delay in baby vaccinations
Immunoassays - Eleven diagnostic assays approved for hepatitis, PSA, alpha-fetoprotein
Immunology - Autoimmune tendencies spark inflated immune response to adeno-associated virus
Immunology - Bucillamine uses dual pathways to regulate VEGF in systemic fibrosis patients
Immunology - FDA grants orphan drug designation for Altastaph
Immunology - Immunogene therapy prevents angiogenesis in study animals
Immunology - Swift production of neutralizing antibody halts hepadnavirus infection
Infant Care - Contact lenses could help some infants
Infectious Disease - Epidemiology of human M. bovis infection in the U.K. characterized
Infectious Disease - Medical examiner database useful for fatal infectious disease surveillance
Influenza - Flu vaccine's results leave experts uncertain of next season preparations
Influenza - Report finds inactivated influenza virus vaccines effective in children
Influenza - Vaccine development against H5N1 virus "should be made a priority"
Influenza - WHO adds Fujian flu to vaccine list for next winter
Influenza Vaccine - Benefit of new influenza vaccine in healthy children investigated
Influenza Vaccine - Signed consent requirement for influenza vaccination should be eliminated
Information Technology - Antibacterials developer selects software for chemical reaction planning
Information Technology - CIBEX contains experimental data on gene expression research
Information Technology - Cottage Health Care System selects ibex PulseCheck
Information Technology - Hershey Medical Center selects MedAssets-OSI Systems
Information Technology - Lawson signs contract with Palmetto Health
Information Technology - New patient-monitoring system helps improve patient care
Information Technology - Researchers develop a retroviral tagged cancer gene database
Information Technology - SNP500Cancer database helps researchers map diseases
Information Technology - Use of IT in hospitals bodes well for future, report says
Insomnia - FDA allows IND for extended-release formulation of Sonata
Irritable Bowel Syndrome - Awareness, understanding of IBS key to promoting new drugs
Kaposi Sarcoma - Mechanisms of HHV-8 IL-6 mimicry determined
Kidney Cancer - Tumor-based vaccine shows promise
Kidney Disease - Cardiovascular disease risk factors may also predict development of kidney disease
Kidney Disease - Leptin, ghrelin, and cytokines have nutritional impact in kidney disease
Kidney Disease - Many vaccines are safe and effective in patients with chronic kidney disease
Kidney Failure - BMP-7 prevents bone disease in a model of chronic kidney failure
Klippel-Trenaunay Syndrome - Gene for rare vascular disorder identified
Laboratory Systems - Johns Hopkins installs six BenchMark XT systems
Laryngoscopy - The merits of suspension laryngoscopy should be reexamined
Legal Decisions - Florida legislature still unclear on end-of-life laws
Legal Issues - Arkansas insurer files notice of appeal in 'any-willing-provider' case
Legal Issues - Attorney given prison sentence for City of Hope theft case
Legal Issues - Federal appeals court upholds dismissal of Zoloft lawsuit
Legal Issues - German doctor arrested in connection with eight cases of "mercy killing"
Legal Issues - Hospital in Pennsylvania settles suit against Independence Blue Cross
Legal Issues - Kindred Healthcare announces settlement with Kentucky Attorney General
Legal Issues - Methadone clinics tackled by West Virginia house
Legal Issues - Restrictions pursued for OTC cold medications containing meth ingredient
Legal Issues - U.S. Justice Department demands abortion records
Legal Issues - Washington state lawmakers push 'three strikes and you're out' for doctors
Legal Issues - Women accuse chiropractor of rape
Leishmaniasis - New antibiotic improves treatment of parasitic infection
Leishmaniasis - RAPD method allows Leishmania species differentiation
Leptin Studies - Local, systemic angiotensin II regulate adipocyte leptin release differently
Leptin Studies - Melanocortin receptors mediate leptin effects on hypothalamic neurons
Letter to the Editor - Domestic violence, guns among topics of women's health conference
Leukemia - GATA1 mutations are common children with Down syndrome
Leukemia - Generic Purinethol tablets receive marketing clearance
Leukemia - Immature B cell cancers generate proangiogenic growth factor
Leukemia Pathogenesis - E2a/Pbx1 triggers proliferation of SCF-dependent pro-T cells
Leukemia Therapy - BAVC SCT conditioning comparable to BuCy regimen
Leukemia Therapy - Novel regimen effective for JMML patients without stem-cell donors
Leukemia Therapy - SCT with voriconazole treatment feasible for AML with pulmonary aspergillosis
Leukemia Therapy - Utility of STR markers for post-SCT chimerism evaluated
Limb Ischemia - Cutting balloon angioplasty is feasible for symptomatic limb ischemia
Liposuction - Liposuction improves cholesterol, glucose, and insulin metabolism
Liver Cancer - Management of inferior vena cava injury during hepatectomy is discussed
Lung Biopsy - Contrast-enhanced sonography guides transthoracic biopsy of lung lesions
Lung Cancer - Lung cancer compound phase II trial commences
Lung Cancer - Peroxisome proliferator-activated receptor-gamma activation inhibits NSCLC
Lymphoma Therapy - Mantle cell lymphoma treatment reviewed
Macromolecular Modeling - Insight II and Catalyst now available on Linux
Malaria - P. vivax heightens erythrocyte deformability
Malaria - In African highlands, climate extremes are critical factor in malaria epidemics
Malaria Drug Resistance - Molecular basis of P. jirovecii atovaquone resistance clarified
Malaria Genomics & Genetics - Fc gamma receptor IIa polymorphism linked to severe malaria in West Africa
Malaria Genomics & Genetics - Murine plasmodial ABC genes identified
Malaria Pathogenesis - Platelets reorient endothelial adhesion of infected RBC
Malaria Pathogenesis - Some malaria parasites are capable of HA and CSA adhesion
Malaria Vaccine - Polymorphism reducing P. falciparum rosetting protects against malaria
Market Analysis - Advanced wound care dressings to be growth engine of European market
Market Analysis - Healthcare costs tops list of Americans' concerns
Market Analysis - Healthcare spending growth projected to nearly double in next decade
Maternal Mortality - WHO: More effort needed to cut the half-million annual deaths in childbirth
Medicaid - Auditors say Houston school district should repay federal funds
Medical Malpractice - Doctors leaving nursing-home patient care because insurers won't cover them
Medical Malpractice - Gynecologist sentenced to 45 years for sexually abusing patients
Medical Malpractice - Kentucky House panel approves proposal for medical malpractice insurance
Medical Malpractice - U.S. Treasury secretary calls for lawsuit damage cap
Medicare - Analysis explains why advantage rate increases for 2004 will vary across U.S.
Medicare - Canadian analysts say new U.S. law hurts seniors, helps drug firms, insurers
Medicare - Cancer experts ask Congress to hold chemo reimbursement rates at 2004 level
Medicare - Choosing hospice care raises federal program costs for last year of life
Medicare - State pharmacy assistance programs help reduce costs, improve patient safety
Melanoma - Data on autologous cell vaccine published
Melanoma - Nodal nevi are more frequent in patients with melanoma-associated cutaneous nevi
Melanoma - The Libechov minipig model is suitable for studying human melanoma
Meningitis - Health groups recommend temporary suspension of pediatric vaccine dose
Menopause - FDA approves EstroGel transdermal gel for estrogen therapy
Menopause - Hot flashes, night sweats treatment now available in U.S. pharmacies
Menopause - Progestins can be a hindrance or a help to women with certain disorders
Mental Health - Amnesia blamed on nightmare, though skeptics remain
Mental Health - Depression and anxiety relate to alexithymia in women with eating disorders
Mental Health - Hundreds of coins found in patient's belly
Mental Health - Late-night mental health niche filled in Maryland
Mental Health - Law to force treatment for mentally ill upheld by New York high court
Mental Health - Mental health reform plan nothing new
Mergers and Acquisitions - Acquisition gives Nanogen foothold in point-of-care diagnostics market
Mergers and Acquisitions - Acquisition of Applied Molecular Evolution complete
Mergers and Acquisitions - Agreement signed to be acquired by Fisher Scientific
Mergers and Acquisitions - Amedisys provides update on purchase of home care agencies
Mergers and Acquisitions - Attentus Healthcare to negotiate acquisition of SunLink Health Systems
Mergers and Acquisitions - China-based pharmaceutical company acquired
Mergers and Acquisitions - FTC clears way for merger of drug benefits companies
Mergers and Acquisitions - GTCR Golder Rauner announces acquisition
Mergers and Acquisitions - Genome Therapeutics merger complete; merged company focused on anti-infectives
Mergers and Acquisitions - Harvard inks letter of intent to acquire assets of antibody development company
Mergers and Acquisitions - HepatoTech's cell culture business acquired
Mergers and Acquisitions - Invitrogen completes acquisition
Mergers and Acquisitions - Microwave surgical cardiac ablation developer acquired by Guidant
Mergers and Acquisitions - Neurologix completes merger
Mergers and Acquisitions - SJ Strategic Investments will not pursue acquisition proposal
Mergers and Acquisitions - University of Pittsburgh Medical Center acquires biotechnology firm
Mesothelioma - CT, MR, and PET imaging should be used to assess malignant pleural mesothelioma
Metastatic Cancer - CT and MRI can identify inferior vena caval thrombus in metastasis to the kidney
Methadone - Nebraska aims to protect children from methadone laboratories
Molecular Biology - Computer scientists develop tool for mining genomic data
Morbid Obesity - Kidney transplants can be successfully performed in morbidly obese patients
Mowat-Wilson Syndrome - Frameshift mutation involved in syndromic corpus callosum agenesis
Multiple Sclerosis - Neutralizing antibodies negatively impact MS therapy's effectiveness
Multiple Sclerosis - Widespread nerve fiber damage associated with fatigue
Muscle Injury - Quadriceps femoris function is restored with a latissimus dorsi muscle transfer
Mutagenesis - Altered iron associates with mutations in those with chronic hepatitis C
Mycobacterium - Luminex profiling system applied to M. tuberculosis genotyping
Myelodysplastic Syndromes - Low-dose topotecan in myelodysplastic syndromes has no effect
Myelodysplastic Syndromes - Treatment monitoring in MDS patients reviewed
Myocardial Infarction - Insulin decreases inflammation, aids clot-busting drugs in heart attack patients
Nanomedicine Trends - Nanobiotech pioneers predict nanomedicine impact within 5 years
Nanotechnology - Synthetic DNA strand could be copied easily
Nerve Damage - Key advance reported in regenerating nerve fibers
Nerve Damage - Stem cells found in adults may repair nerves
Neuroendocrine Tumors - Genetic abnormalities are related to neuroendocrine tumor progression
Neuroendocrine Tumors - Specialty nurses benefit patients with neuroendocrine tumors
Neurology - In utero exposure to alcohol appears to boost risk of psychiatric disorders
Neurology - Mother's exposure to lead linked to schizophrenia in children
Neurology - Small amounts of alcohol or anesthetics may damage the developing brain
Neuroscience - 5HT3 receptors quantified in brain of serotonin-transporter-deficient mice
Neuroscience - Gender should be noted when emotions are mapped on functional brain images
Neuroscience - Mast cells localize near blood vessels in the human area postrema
Neuroscience - Protein synthesis necessary for dendritic spine proliferation in adult brain
Neuroscience - Small interfering RNA's curtail the Huntington disease gene in cell cultures
Neurotoxins - Method to measure toxicity of polypeptides on neuroblastoma cells developed
Nicotine Addiction - Maternal smoking compromises lung function of offspring in several ways
Nicotine Addiction - Tests suggest some predisposed to smoke
Non-Hodgkin Lymphoma - Hair dye use increases blood-cancer risk in women
Nursing Care - Violations found at nursing home where nurse charged after patient death
Nursing Shortage - Plan announced to aid nursing students in Iowa
Nutrition - Food pyramid recommendations made to U.S. Congress
Nutrition - Government computerizes calorie plan
Nutrition - Group suggests dietary intake levels must be realistic for consumers
Nutrition - Wild Oats Markets removes all products containing hydrogenated oils
Obesity - Grant aims to battle obesity in Honolulu
Obesity Genomics and Genetics - Dissection of multigenic obesity traits in congenic mouse strains reported
Obesity Risk Factor - Hypothalamic genes implicated in Psammomys obesus obesity identified
Obesity Survival and Mortality - Mild obesity increases risk of anastomotic leakage after organs transplant
Obesity Therapy - Salix matsudana leaves exhibit antiobesity action
Obesity Therapy - Anorexigenic fatty acid synthase inhibitor is nonspecific neuronal activator
Obstetrics - Continuous spinal anesthesia feasible for C-section in CHF patients
Obstetrics - Epidural analgesia relieves pain caused by acute symphysis pubis dysfunction
Obstetrics - Factors identified that may contribute to higher stillbirth risk on weekends
Obstetrics - Infants of women who used SSRIs while pregnant show variety of neurobehaviors
Obstetrics - Maternal selenium deficiency increases oxidative stress in fetuses
Obstetrics - Number of cesarean deliveries in Pennsylvania continue to rise
Obstetrics - Prophylactic ondansetron won't alleviate fentanyl-induced itching during labor
Occupational Therapy - Virtual play boosts disabled children's self-image
Oncogenesis - The proto-oncogene hSecurin is highly expressed in some myeloid leukemias
Oncology - COX-2-derived prostaglandin E-2 is a potent breast cancer stimulant
Oncology - Effusions from patients with cancer harbor high levels of angiostatin
Ophthalmic Antibiotic - FDA approves Neomycin, Polymyxin B Sulfates, Bacitracin Zinc ophthalmic ointment
Ophthalmology - Agents aimed at wound healing elements could treat choroidal neovascularization
Oral Cancer - Decades of surgical, therapeutic advances have improved oral cancer survival
Oral Cancer - Smoking black tobacco and drinking alcohol increases risk of oral cancer
Orthopedics - Rapid bone loss is a transient and unfixed phenomenon
Orthopedics - Soluble VEGF isoforms are essential for epiphyseal vascularization
Osteoarthritis - Seniors with best drug coverage more likely to use prescription pain medication
Osteoporosis - Bias clouds attempts to assess quality of life in women with hip fractures
Osteoporosis - Education is key to preventing vertebral compression fractures in the elderly
Osteoporosis - Few women regard spinal fractures as a sign of bone thinning
Osteoporosis - Growth hormone appears to limit fracture risk in people with acromegaly
Osteoporosis - Hormone found to protect bones
Osteoporosis - Patients hospitalized for fracture are being under-treated for osteoporosis
Osteoporosis - Specific bone loss interventions help patients after hip fracture
Osteosarcoma - Noninvasive approach to salvaging limbs helps young bone cancer patients
Ovarian Cancer - Anticancer drug Phenoxodiol produces promising results
Ovarian Cancer - COX-2 and angiogenic status yield ovarian carcinoma prognosis
Ovarian Cancer - Experimental drug used to treat recurrent disease shows promising results
Ovarian Cancer - Guidelines help ovarian cancer patients receive proper treatment referrals
Ovarian Cancer - Raf is necessary for Ras transformation of ovarian epithelial cells
Packaging - Agreement inked for prefilled dual chamber pharmaceutical mixing device
Pain Medicine - Accidental dural puncture during epidural anesthesia causes subdural hematoma
Pain Medicine - Empathy, placebo's power studied
Pain Medicine - Epidural analgesia for labor may be linked to breast-feeding problems
Pain Medicine - Quinolizidine template for opioid receptor ligands synthesized
Pain Medicine - Some patients want to know more than typically offered about labor analgesia
Pain Medicine - Synacthen Depot offers no advantages for treating postdural puncture headache
Pain Medicine - Women with temporomandibular disorder show a cervical lordorsis angle link
Pancreatic Cancer - Multidetector CT may improve imaging of pancreatic adenocarcinoma
Parasitology - Discovery could lead to better treatment for cryptosporidum infections
Parkinson Disease - Link found between parkinsonism and dementia
Patents - Company announces notice of allowance on key AOD9604 obesity patent
Patents - Company granted United States patent for cyclosporine antibodies
Patents - Company receives patent for its adenoviral formulation technology
Patents - Key nanotechnology patent issued
Patents - Locus Pharmaceuticals wins drug-design patents
Patents - New patent on gene targeting broadens genetics company's portfolio
Patents - Patent issued for exosome technology - a new approach to immunology
Patents - Ruling invalidating University of Rochester pain-drug is upheld
Patient Privacy - Judge orders patients names to be turned over by agency
Patient Safety - Minneapolis-St. Paul Children's Hospitals convert to Masimo SET Oximetry
Pediatric Cancer - Computer program aids chemotherapy regimen planning
Pediatric Cancer - MYCN oncogene mediates multidrug resistance-associated protein in neuroblastoma
Pediatric Urology - Croatian and American children bear similar-appearing kidney stones
Pediatrics - Centrality indices characterize fat deposition in youngsters
Pediatrics - Dental and minor physical anomalies reveal youth with developmental disorders
Pediatrics - Premature babies of anxious moms more likely to have worse development outcomes
Pelvic Reconstruction - Transpelvic vertical rectus flaps can cover complex perineal wounds
Perception - Food tastes stronger when you're hungry
Peripheral Artery Disease - IND Application filed for peripheral artery disease therapy
Personnel - Ahmed named senior VP of global productivity at drug discovery firm
Personnel - Ashleigh Palmer named new chief business officer at biotech company
Personnel - Biomaterials company announces sales and marketing organization changes
Personnel - Biopharmaceutical company names Shirley Liu Clayton chief executive officer
Personnel - Biotechnology company announces appointment of new independent director
Personnel - Boess named VP, chief financial officer at pharmaceutical firm
Personnel - Brewer named to biotech company's board of directors
Personnel - Company names new chief technology officer and VP, development
Personnel - Daniel S. Lynch named CEO and director of Erbitux maker
Personnel - David B. Karpf, MD, named chief medical officer
Personnel - Dennis J. Allingham named president and CEO of biomaterials company
Personnel - Device company names Vartan Ghazarossian president and CEO
Personnel - Device firm announces management team changes
Personnel - Device firm names John Grotting chairman, CEO
Personnel - Diabetes company names Michael Mawby as chief government affairs officer
Personnel - Dr. Pradeep Sanghvi to join drug-delivery company
Personnel - Former McKesson executive joins Opus Healthcare Solutions
Personnel - Gary Beil named interim CFO of DaVita
Personnel - Hawkins named new CEO at biotech firm
Personnel - Hythiam names David Smith, MD, as senior vice president of medical affairs
Personnel - Integrated Healthcare Systems appoints Jay C. Grant as vice president, sales
Personnel - James Pennington, MD, joins biopharmaceutical company as chief medical officer
Personnel - John H. Jungbauer joins cardiothoracic-device maker as CFO
Personnel - Kuo, Sedlack named to board of directors at vaccine development company
Personnel - Life sciences company announces new director of business development
Personnel - Manny Villafana to step down as chairman of board of directors
Personnel - Medical device manufacturer announces product advisory board
Personnel - Medical products company names new senior vice president
Personnel - Men's health company taps Greg Deener to head marketing and sales team
Personnel - Mississippi Health Department names new state epidemiologist
Personnel - Mozambique premier to take up research post at U.N. health agency
Personnel - New member appointed to U.S. Health & Human Services advisory committee
Personnel - Pharmaceutical company announces new chief financial officer
Personnel - Pharmaceutical firm announces promotions, management changes
Personnel - Protein therapeutics company announces additions to management team
Personnel - Regence names new executive vice president, health care services
Personnel - Systems regulatory compliance company names new VP, quality assurance
Personnel - Venter to chair scientific advisory board at genomics firm
Personnel - Vice chairman at company resigns at clinical lab firm
Phacoemulsification - Iris hooks can stabilize the capsular bag during phacoemulsification
Pharmaceutical & Drug Development - Novel class of non-covalent cathepsin K inhibitors reported
Physical Activity - Massachusetts girls lag behind boys in sports participation
Physical Fitness - Health plan introduces wellness program in Arizona
Plasma - Scientists tackle human blood plasma proteome
Poliomyelitis Vaccine - Vaccine-derived polioviruses decline in patients with poliomyelitis
Post-thrombotic Syndrome - Post-thrombotic syndrome often complicates deep venous thrombosis
Postoperative Pain - LogPad electronic patient diary to be used in postop pain clinical trial
Postpartum Depression - Magellan identifies barriers to diagnosis, treatment of postpartum depression
Premenstrual Syndrome - New premenstrual syndrome supplement pack launched
Presbyopia - FDA panel recommends approval of CK System for near vision improvement
Prescription Drug Costs - New Hampshire leader suggests state buy drugs in bulk and pass on savings
Prescription Drug Importation - House votes to let Washington state buy drugs from Canada
Preventive Medicine - Practice-based education for doctors improves delivery of preventive childcare
Product Licensing - Nuvelo licenses rNAPc2, an anticoagulant
Prophylactic Antibiotics - Antibiotic prophylaxis in aseptic orthopedic surgery is evaluated
Prostate Cancer - Beta-catenin nuclear signaling molecule may be an oncogene in prostate cancer
Prostate Cancer - New view of recurrent prostate cancer proposed
Prostate Cancer - Sulforaphane reduces PC-3 xenografts in vivo in a murine model
Prostate Cancer - Vibroacoustography holds promise for brachytherapy metal seed imaging
Prosthetics - Cadence HP prosthetic foot now rated up to 350 pounds
Protease Inhibitors - Boosted saquinavir demonstrates superior lipid safety profile vs. Kaletra
Proteomics - Divalent cations augment endostatin after heparin and heparan sulfate binding
Proteomics - Lilly makes $3.2 million commitment to new research center
Proteomics - Phe*-Ala-based pentapeptide mimetics are BACE inhibitors
Proteomics - ProTherm, version 4.0, is thermodynamic database for proteins and mutants
Proteomics - Prostaglandin-J2 has oxygen-dependent effects on VEGF expression
Proteomics - Recombinant human erythropoietin fuels intussusceptive microvascular growth
Proteomics - TrSDB is a proteome database of transcription factors
Proteomics - Update on the 2004 Database of Interacting Proteins reported
Psoriasis - Amevive with common treatments improves chronic plaque psoriasis outcome
Psoriasis - Studies: Tazarotene is well tolerated
Psoriasis - U.S. Soriatane (acitretin) product rights acquired from Roche
Psoriatic Arthritis - Remicade shows promising results in psoriatic arthritis study
Psychology - The coping and defense styles of women with postnatal depression diverge
Psychology - The gravity of one's pregnancy is reflected by certain temperamental traits
Public Health - Infant deaths up in U.S. for first time since 1958
Pulmonary Medicine - Rapid preoxygenation is more effective for women with acute obstetric emergency
Quality Assurance - Respiratory products manufacturer receives FDA warning letter
Quality Assurance - Senate committee OKs medical translator bill
Quality Assurance - Study finds problems with access to credible health information online
Quality Assurance - Sweep of Texas nursing home results in seven arrests
RNA Research - Poly(A) binding protein binds AU-rich RNA via RNA-binding domains 3 and 4
Radiation Oncology - New technology may help doctors more accurately target tumors
Receptor Studies - Cytoskeletal protein 4.1G binds to loop of A1 adenosine receptor
Receptor Studies - RNA editing of serotonin receptor disrupts transactivation of G-protein RhoA
Reproduction - Study: Small newborns indicate higher risk of later stillbirths
Reproductive Medicine - Study finds vasectomy reversal highly effective, even after 15 years
Research Ethics - The link between funding and the disclosure of clinical trial results
Respiratory Medicine - Two formulations of ambroxol hydrochloride tablets are bioequivalent
Respiratory Syncytial Virus - IL-2 expression during RSV infection improves memory CD8 T cell development
Retinopathy - Intravitreal triamcinolone has no impact on VEGF mRNA expression
Salmonella - Assay for detecting salmonella in water used for sprout seeds developed
Schizophrenia - Risperdal Consta significantly reduces need for institutional psychiatric care
Schizophrenia - Ziprasidone improves cognitive function in schizophrenic patients
Scleroderma - Preliminary results reported from phase I/II trial of Cat-192
Sepsis - Docs aim to reduce blood infection deaths
Sepsis - Nitric oxide blockade's role in treating septic shock unclear
Sexual Dysfunction - Future pill for premature ejaculation under study
Sexual and Reproductive Health - Kentucky Senate passes fetal homicide bill
Signaling Networks - Use of its BioMAP technology demonstrated to determine functions of genes
Skin Cancer - Link between tanning devices and skin cancer still unproven but worrisome
Skin Cancer - More patients protect themselves from the sun after skin cancer surgery
Skin Cancer - Sun exposure behaviors correlated with dose of ultraviolet radiation received
Sleep Apnea - Modified surgical procedure appears effective for treating sleep disorder
Smallpox - Few cases of vaccinia transfer reported
Smallpox - Surveillance and containment would be effective against deliberate attack
Smoking Ban - Ireland will outlaw smoking in pubs and other workplaces
Spectroscopy - Laser method identifies, counts toxic molecules
Spinal Cord Injury - Neurologists create a font of human nerve cells
Spinal Cord Injury - Single neurons found to control whisker movement in rats
Spinal Surgery - The risk of acute pancreatitis is increased in children after spinal fusion
Sports Medicine - Gene therapy could lead to super athletes
State Medicaid - Financing measures sent to New Mexico's governor
State Medicaid - Massachusetts governor to propose new way to care for elderly
State Medicaid - Tennessee governor hits the road to promote plan
Stem-Cell Research - Four-color immunofluorescence enables mesenchymal stem cell identification
Stem-Cell Research - Hedgehog-independent pathway identified for oligodendrocyte development
Stem-Cell Research - OLIG2 inhibits astrocyte differentiation
Stem-Cell Transplantation - Minisequencing useful for SNP analysis
Stem-Cell Transplantation - Post-SCT immunological recovery similar in CLL, NHL patients
Stem-Cell Transplantation - Proteasomal cleavage analysis useful for mHps prediction
Stem-Cell Transplantation - Rituximab effective against post-SCT autoimmune hemolytic anemia
Stensen Duct Repair - A vein graft is used as a conduit for Stensen duct defect reconstruction
Stress Urinary Incontinence - Study: More than one out of three women with urinary incontinence have SUI
Stroke - Brain cooling technology may reduce stroke damage
Study Ethics - Unusual study tests artificial blood without patients' consent
Survival & Mortality - Most deaths after hospitalization for vertebral fracture are due to comorbidity
Systemic Lupus Erythematosus - Enrollment complete in confirmatory phase III clinical trial of Prestara
Teratomas - Gonadal teratoma behavior depends upon tumor site and patient age
Thrombocytopenia - Thrombotic thrombocytopenic purpura linked to mutation in ADAMTS13
Thrombopoietin - TPO and anti-FLAG antibodies differentially affect receptor signaling
Thyroid Cancer - Ultrasonography can help guide fine needle aspiration biopsy of thyroid nodules
Thyroid Carcinoma - Quality of life lower during periods of hypothyroidism in thyroid carcinoma
Tick-borne Encephalitis - Widespread immunization reduces incidence of tick-borne encephalitis
Tissue Engineering - Cultured alumina ceramics could prevent aseptic loosening of joint implants
Tissue Engineering - Pioneering techniques may overcome some current challenges
Tobacco Proposal - Congress urged to link buy out of farmers with health regulations
Tobacco Use - Smoking ban proposed at Kentucky capitol
Total Hip Arthroplasty - BiCONTACT revision stems with distal interlocking screws prove satisfactory
Total Hip Arthroplasty - COX inhibitors compared for heterotopic ossification following arthroplasty
Total Hip Arthroplasty - Cementless femoral stems are improved by a high-offset design
Total Hip Arthroplasty - Hydroxyapatite-coated stems may be better than porous-coated stems
Total Knee Arthroplasty - 10-Year survival of PCL-substituting TKA in young rheumatoid patients nears 100%
Total Knee Arthroplasty - Osteolysis in posterior stabilized TKA is best detected with oblique films
Toxicogenomics - FDA supporting toxicogenomic research through ArrayTrack
Toxicology - More women are using atypical antipsychotics during pregnancy
Toxoplasmosis - SAG2 internal image of anti-idiotype antibody protects against toxoplasmosis
Transplant Medicine - Database on blood and marrow stem cell transplants now available online
Transplant Medicine - Hepatocyte growth factor gene therapy improves islet transplantation outcomes
Transplant Medicine - Physicians predict risks of deadly infections after cord blood transplants
Trends - Market growing for energy-based therapeutic technologies
Tuberculosis - Gates Foundation commits $82.9 million to develop new tuberculosis vaccines
Tuberculosis - Nitric oxide mediates anti-TB effects of vitamin D
Tuberculosis Diagnostics - Antibody response to mycobacterial ESAT-6 characterized
Tuberculosis Diagnostics - Glycolipidic antigens can improve TB serodiagnosis
Tuberculosis Diagnostics - Novel mass spectrometry assay aids genotype identification
Tuberculosis Diagnostics - Serum ferritin levels marking iron deficiency in TB patients determined
Tuberculosis Drug Resistance - IS6110 augments phoP transcription in MDR TB
Tuberculosis Epidemiology - TB genotypes in Casablanca characterized
Tuberculosis Pathogenesis - Cholesterol-specific receptor enables mycobacterial cell entry
Tuberculosis Prevention - Clinical trial of new TB vaccine begins
Tuberculosis Proteomics - Structure of M. tuberculosis MPT51 protein characterized
Tuberculosis Therapy - Celiac disease can impair TB therapy
Tuberculosis Therapy - Isoniazid more cost-effective than rifampin-pyrazinamide for latent TB treatment
Tumor Growth - Amine oxidases and tumors are correlated
Type 1 Diabetes Pathogenesis - Expression of MHC molecule leads to thymic deletion of diabetogenic T cells
Type 1 Diabetes Pathogenesis - Self-peptide with superagonist activity blocks type 1 diabetes
Universal Healthcare - Group applauds Massachusetts doctors for supporting single-payer system
Vaccine Development - Tumor-pulsed dendritic cells activate antitumor protection
Vaccinia Virus - Protein kinase has essential catalytic role in vaccinia virus morphogenesis
Varicella-Zoster Virus - Pathogenetic tropism of varicella-zoster virus to human hepatocytes reported
Vascular Dilatation - Vascular dilatation in the pelvis can be due to obstruction or tumor
Vector Delivery - Single photon emission computed tomography tracks genes in minute lung tumors
Vector Development - Coupled carriers may offer a better way to transfer genes to tumor cells
Vector Development - Hybrid vectors generate cells that sustain long-term transgene expression
Vector-borne Disease - E.U. research aims for prevention, control of highly transmissible animal diseases
Vectors and Zoonoses - Multiple anopheline digestive trypsins identified
Venous Leg Ulcers - Frozen OrCel promotes superior healing in venous leg ulcers, study shows
Venous Thromboembolism - Sodium fondaparinux, heparin compared for preventing VTE
Veteran Care - Staffing at Mississippi veterans' homes questioned
Viral Genomics - Denaturing high-performance liquid chromatography can do HCV genotyping
Viral, Bacterial Detection - SMD technology plus lab card device to provide diagnosis of organisms
Virology - A new expression vector augments the cloning of full-length HBV genomes
Virology - Multiply modified retroviral vectors carry high titers in lab evaluations
Virology - gp64-Pseudotyped vectors are appealing because of narrower cell attraction
Vitreoretinal Disease - Horizontal suture fixation of an intralocular lens should be avoided
Wasting Syndrome - Ghrelin upregulated in cachectic nude mice bearing human melanoma cells
Wiskott-Aldrich Syndrome - Wiskott-Aldrich syndrome protein provides little selective benefit to B cells
Women's Health - Clip markers can migrate after imaging-guided directional vacuum-assisted biopsy
Women's Health - Digital mammography has not yet improved cancer detection rates
Wound Care - Angiogenic growth factor is required for wound healing but not wound closing
Wound Care - Ascorbic acid modulates the effects of radiation-delayed wound healing
NewsRx also is available at LexisNexis, Gale, ProQuest, Factiva, Dialog, Thomson Reuters, NewsEdge, and Dow Jones.