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Hypoxia

Project demonstrates inherited ability to adapt to life at high altitudes

Published in Health and Medicine Week, March 8th, 2004

Tibetans' muscles are better protected against hypoxia at high altitudes than those of lowland dwellers since Tibetans produce more of the enzymes that neutralize free radicals in muscle tissue.

This ability to adapt to life at over 3500 meters above sea level is at least partly inherited. This was the finding of a Swiss National Science Foundation project undertaken by the sports physician Hans Hoppeler from the University of Berne.

High-altitude expeditions are physically demanding because the oxygen content of the air decreases as altitude increases. At 5000 meters there is just one-third the amount of oxygen that there is at sea level. This...

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