Health & Medicine Week
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Angiology
Insulin-like growth factor I plasmids augment vessel growth where needed
March 22nd, 2004
Insulin-like growth factor I plasmids augment vessel growth where needed. "Angiogenesis, the formation of neovessels from the endothelium of preexisting vessels, is stimulated by soluble angiogenic factors. Insulin-like growth factor I (IGF-I) stimulates myogenesis and induces nerve regeneration after injury, and it has been shown to stimulate angiogenesis. However, the in vivo angiogenic effects of IGF-I in regenerating and diabetic muscle have yet to be described," scientists in the United States report. "Therefore, we studied the effects of human IGF-I (hIGF-I) delivered by a plasmid-mediated therapy on angiogenesis in mouse models of these two...
Source: Health & Medicine Week (2004-03-22)
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