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Health & Medicine Week

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Anthrax Vaccine



Serological correlate of protection in rabbits for anthrax vaccine identified



March 22nd, 2004

Researchers have identified a serological correlate of protection in rabbits for a recombinant anthrax vaccine.

According to a study from the United States, "In these studies, a serological correlate of protection against anthrax was identified in New Zealand white (NZW) rabbits that had been given one or two injections of various amounts of recombinant protective antigen (rPA) combined with aluminum hydroxide adjuvant (Alhydrogel). Rabbits were subsequently challenged by the aerosol route with spores of the Ames isolate of Bacillus anthracis."

"Results suggested that the antibody response, as determined by the quantitative anti-rPA IgG ELISA...


Source: Health & Medicine Week (2004-03-22)

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