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Health & Medicine Week

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Bacteriology



Preliminary X-ray analysis of human-specific toxin intermedilysin reported



March 22nd, 2004

Researchers report results of a preliminary X-ray analysis of the human-specific toxin intermedilysin in a recent issue of Acta Crystallographica Section D - Biological Crystallography.

"Intermedilysin is a human-specific toxin from Streptococcus intermedius, which is part of normal human oral flora. The bacterium is an opportunistic pathogen with a tendency for deep-seated infection in the brain and liver. Intermedilysin belongs to the cholesterol-dependent cytolysin (CDCs) family of toxins, which have been identified in several different bacteria including the serious human pathogens S. pneumoniae and Clostridium perfringens," scientists in...


Source: Health & Medicine Week (2004-03-22)

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