Malaria Risk Factor
IL-1 gene variants have limited effect on malaria susceptibility
Published in Health and Medicine Week, March 22nd, 2004
IL-1 is "a potent endogenous pyrogen and inducer of the acute phase response, and these innate immune responses are an important part of the human host's initial reaction to infection by the malaria parasite," scientists in England explained. "In addition, several single-nucleotide polymorphisms (SNPs) in this region have previously been demonstrated to be associated with susceptibility to infectious disease."
"Therefore, a possible association with malaria susceptibility was investigated," in a study conducted by A.J. Walley and colleagues at the Wellcome...
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