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Health and Medicine Week

Susan Hasty, Publisher

Table of Contents . . . March 29th, 2004

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Health and Medicine Week | Other Publications

Liver Disease - Hepatitis C virus carriers need access to quality, continuous care

Liver Cancer - Radiofrequency ablation liver treatment establishes reimbursement policies

Lipid Studies - Negative energy balance and exercise improves lipid profiles

Lipid Studies - Lipoproteina levels respond to life-style changes in obese adults

Licensing Agreement - Endo enters agreement to codevelop new drugs for pain

Leukemia Therapy - Unrelated cord blood transplantion feasible for adult AML patients

Leukemia Therapy - Effects of class I HLA NK epitopes on haploidentical SCT outcome determined

Leukemia Pathogenesis - E2a/Pbx1 triggers proliferation of SCF-dependent pro-T cells

Leukemia - TLX1 overexpression indicates a good prognosis for adults with T-cell ALL

Leukemia - Sibling donor for Ph- bone marrow transplantation does not increase survival

Leukemia - Bone marrow transplant from partially mismatched family donor is feasible

Leptin Studies - Leptin resistance in obesity related to defects in leptin signaling pathways

Leptin Studies - Cocaine transcript stimulates lipid metabolism to control body fat accrual

Leishmaniasis - Sesquiterpenes inhibit multidrug-resistance in Leishmania tropica

Legislative Issues - Kentucky seeking to lure more health insurers

Legislative Issues - Bill encourages retired physicians to volunteer services

Legislative Issues - Iowa Senate passes bill encouraging long-term care insurance

Legislative Issues - Any-willing-provider law back under wraps in Arkansas

Legal Issues - Woman with possible exposure to hepatitis A sues Taco Bell

Legal Issues - Suspended psychologist loses Ohio license

Legal Issues - Woman charged with identity theft after posing as licensed practical nurse

Legal Issues - Pharmaceutical dosage division transfers operating revenues to joint venture

Legal Issues - Pennsylvania sues drug makers over pricing practices

Legal Issues - Colorado committee backs second bill to stop fast-food lawsuits

Legal Issues - Ex-professor to be sentenced in missing plague vials case

Legal Issues - Analysis: Black-lung bill would double lawsuit awards

Laser Technology - Company announces nationwide implementation of 3D laser-scanning technology

Laryngeal Tumors - Early treatment of laryngeal lesions is necessary to achieve cure

Laparoscopic Surgery - Intracorporeal ribbon gauze can help maintain hemostasis in laparoscopic surgery

Langerhans Cell Histiocytosis - Common virus may contribute to uncommon bone disease

Laboratory Services - Swedish Medical Center inks lab-services agreement with LabCorp

Labor & Delivery - Traumatic delivery not likely cause of brain hemorrhage in month-old babies

Labor & Delivery - Occipito-posterior position deliveries won't impact subsequent pregnancies

Knee Replacement - New knee surgery offers speedy recovery

Kidney Disease - New treatment may help patients with kidney failure

Kidney Disease - African Americans unaware of high kidney disease risk

Ischemia - Effects of tPA and PAI-1 on blood vessel tone described

Invasive Aspergillosis - Zadaxin demonstrates anti-fungal efficacy in invasive aspergillosis study

Interstitial Cystitis - New drug combinations manage the symptoms of a painful bladder disorder

Internet - Online hospital access draws critics

Insulin Resistance - Research: Lower chromium levels linked to increased risk of disease

Insulin - Pfizer and Aventis seek approval to market Exubera in Europe

Insulin - Phase II trial of insulin sensitizer MBX-102 begins

Insulin -  Momordica charantia fruit suppresses blood glucose

Inspections - Medical device manufacturer reports conclusion of FDA inspection

Insomnia - Study: Indiplon effective in treating elderly patients with difficulties maintaining sleep

Insomnia - Company begins trial for extended release formulation of Sonata

Insomnia - FDA issues approvable letter for ESTORRA

Injury Prevention - Alcohol-related emergency department visits more frequent than believed

Information Technology - Web-based retail pharmacy network enrolls with RxScan to minimize errors

Information Technology - Wireless solutions help improve patient care

Information Technology - Polly Ryon Memorial Hospital selects Amelior ED patient care system

Information Technology - Pilot program aims to prevent Medicaid fraud, abuse, waste

Information Technology - New Jersey center joins ranks of ProSolv CardioVascular users

Information Technology - Network to allow electronic exchange of prescription information

Information Technology - Internet-based disease tracking system debuts in Michigan

Information Technology - MEDecision delivers integrated medical management to BCBS of Massachusetts

Information Technology - IASIS awards McKesson solutions $30 million IT contract

Information Technology - Healthaxis augments marketing and sales team with two new appointments

Information Technology - East Jefferson General Hospital to adds clinical IT solutions

Information Technology - HealthPartners Clinics introduce online appointment scheduling

Information Technology - Bradley Memorial Hospital selects Eclipsys Outsourcing

Information Technology - Anthem Blue Cross Blue Shield in Colorado Launches RelayHealth service

Information Technology - Allscripts announces new e-prescribing solution for physicians

Influenza Vaccine - Children with nephrotic syndrome have adequate response to influenza vaccine

Influenza - Targeted treatment could contain pandemic influenza

Inflammatory Bowel Disease - MRI useful tool in diagnosing IBD in children

Inflammatory Bowel Disease - IBD is a risk factor for thrombosis

Inflammation - Rosiglitazone reduces acute inflammation

Infertility Treatment - European Commission approves Gonal-f Filled-by-Mass prefilled pen

Infectious Disease - Epidemiology of human M. bovis infection in U.K. characterized

Infectious Disease - CIEF-WCID may enhance norovirus testing

In Vitro Fertilization - Study supports move toward single births

Immunology - Patient demographics influence granulocytic surface antigen markers

Immunology - Interleukin-1 beta stimulates persistent liver inflammation

Immunology - Interleukin 3 modulates etoposide toxicity on mouse macrophages

Immunology - CD4+CD25+ TR cells control anti-HIV, CMV T-cell activity

Immunology - Immature myeloid DCs predominant in umbilical cord blood

Immune System Disorders - Regulatory approval granted in Germany for Gamunex

Imaging - Grant will fund study of evolutionary computing for biomedical image analysis

ICU Standardization - Avera Health offers eICU care in Dakotas

Hysterectomy - Study reports the standard of care for radical hysterectomy in Europe

Hyperthyroidism - Propylthiouracil is preferred therapy for pregnant women with thyroid disease

Hypertension - Study looks at cost of high blood pressure therapy

Hypertension - High blood pressure is a poor predictor of heart disease

Hypertension - Obesity leads to high blood pressure in the young

Hypertension - High blood pressure in China looks like U.S. 25 years ago

Hypertension - Angiotensin II increases tyrosine hydroxylase production in rat adrenal medulla

Hypertension - Alagebrium chloride approved as generic name for ALT-711

Hypercholesterolemia - Study: Lower cholesterol helps save lives

Hypercholesterolemia - Group seeks ban of anticholesterol drug

Hyperbaric Oxygen Therapy - U.S. Army Corps of Engineers awards contract to supply hyperbaric chambers

Huntington Disease - CRE-mediated transcription increased in Huntington disease

Huntington Disease - Environmental enrichment lessens protein deficits in mouse model of brain disease

Hunter Syndrome - Patient enrollment completed in Hunter syndrome clinical trial

Human Papillomavirus - Data demonstrate HPV testing catches more serious cervical disease

Homosexuality - Biology is behind homosexuality in sheep, study confirms

Hospitalization - Questions raised about do-not-resuscitate orders and shorter hospital stays

Hereditary Antithrombin Deficiency - Company presents ATryn safety and efficacy data

Hepatology - Balanced cytochrome P4502E1 activity is key to treating steatohepatitis

Herbal Supplements - Select Himalaya products available in liquid formulation

Hepatitis Vaccine - Hepatitis B surface antigenemia occurs after hepatitis A and B vaccination

Hepatitis C Virus - Study shows highest sustained response rates reported in hepatitis C patients

Hepatitis E Vaccine - Hepatitis E virus-like particles protect monkeys against HEV infection

Hemophilia A - Marketing authorization granted from EC for Advate

Hematology - Protein 4.2 critical to CD47-membrane skeleton attachment in red cells

Hematology - Therapy containing adeno-associated virus type 8 corrects murine hemophilia A

Hematology - Prostaglandin E1 enhances inhibition of platelet aggregation

Hematology - Mechanisms downstream of P2Y12 ADP-receptor described

Hematology - Antisense knockdown in zebrafish models mammalian prothrombin deficiency

Hematology - Hepatic infiltration of leukemia cells leads to non-alcoholic steatohepatitis

Hematological Malignancies - Dacogen shows activity in hematological malignancy patients, study shows

Heart Failure - Twelfth implant of AbioCor replacement heart reported

Heart Failure Therapy - Biventricular pacing may induce electrical remodeling

Heart Failure - Interstitial purine metabolites elevated during post-MI LV remodeling

Heart Failure - Heartmate XVE shipping with new inflow valve

Heart Failure - Elevated LVEDP may induce myocardial cytokine release

Heart Disease Therapy - Baseline data from heart protection trial reveal dramatic shift in treatment

Heart Disease Therapy - At-home device would check blood thinning

Heart Disease Risk - Microalbuminuria is marker of heart and kidney disease risk in diabetes

Heart Disease Risk - Diet, avoidance of smoking are primary ways for women to prevent heart disease

Cardiology - Safety, efficacy of endovascular intracoronary brachytherapy reviewed

Cardiothoracic Surgery - Grant to support education and innovation in cardiothoracic surgery

Cardiovascular Disease - AT1 receptors linked to insulin resistance-induced vascular dysfunction

Cardiovascular Disease - Angiotensin II causes oxidative stress in hypertension patients

Cardiovascular Disease - Antioxidant therapy helps manage diabetic cardiovascular disease

Cardiovascular Disease - Apolipoprotein risk factors for CVD reviewed

Cardiovascular Disease - CAC deposits linked to elevated LV mass in African-Americans

Cardiovascular Disease - GATA-4 transcription factor regulates cardiac myocyte apoptosis

Cardiovascular Disease - GP Ialpha genotype affects CHD risk

Cardiovascular Disease - Hypertension-induced cardiac remodeling reviewed

Cardiovascular Disease - Leukocyte counts may have prognostic value in acute CVD

Cardiovascular Disease - Myocardial perfusion not linked to peripheral endothelial function

Cardiovascular Disease - New pressure-volume systems launched

Cardiovascular Disease - PET can help determine regional sympathetic function during heart disease

Cardiovascular Disease - Post-revascularization contractile recovery in LV dysfunction patients evaluated

Cardiovascular Disease - Rate of LV hypertrophy progression to heart failure evaluated

Cardiovascular Disease - T wave alternans predicts mortality in congestive heart failure patients

Cardiovascular Disease - Urinary N-BNP suitable for heart failure diagnosis

Cardiovascular Disease Diagnostics - Biomarkers of acute coronary artery disease reviewed

Cardiovascular Disease Therapy - Atorvastatin and fluvastatin have plasma antioxidative activity

Cardiovascular Disease Therapy - Tedisamil has multiple cardioprotective effects

Catheter Care - Articles by nurses describe StatLock benefits

Cell Biology - Core 1-derived O-glycans command successful angiogenesis

Cell Biology - Integrin-linked kinase regulates VEGF-induced vascular morphogenesis

Cell Biology - Scientists publish details of how nutrients, other molecules get into cells

Cervical Cancer - Esoteric laboratory institute converts to ThinPrep Pap Test

Chest Trauma - Resuscitative transverse thoracotomy helps control circulatory arrest

Childbirth - Temperature at birth linked to health later in life

Children's Health Insurance - Participation limit lifted on Idaho program

Cholera - Research on pathogen's life cycle focuses on biofilm formation

Chronic Hepatitis B - Humanized anti-HBs Fab fragment may neutralize hepatitis B surface antigen

Cloning - Life science company introduces RapidTransit Transformation Kit

Collaboration - Agreement signed for Chagas disease blood screening technology

Collaborations - Agreement reached for development of biodefense pathogen, filtration device

Collaborations - Agreements inked to develop novel molecular imaging agents

Collaborations - Apollo Telemedicine Partners with MicroBrightField

Collaborations - Aventis provided with early access to high-throughput GeneChip platform

Collaborations - Biotech firm grants non-exclusive license on its DPD-process to Roche

Collaborations - Cardiovascular discovery collaboration signed with DMI BioSciences

Collaborations - CatchMabs enters commercial bacteriophage production collaboration

Collaborations - Deal signed for development of therapeutic antibodies for cancer

Collaborations - Heart valve maker to partner in deal for commercialization of laser technology

Collaborations - IT service contract signed by biotech firm

Collaborations - Imaging company announces agreement with GlaxoSmithKline

Collaborations - Lexington Medical Center signs cost-management agreement

Collaborations - Partner selected for Amoxicillin Pulsys product candidate

Collaborations - QMed, Inc. to provide diabetes and coronary disease management to WHA

Colon Cancer - FDA meeting to discuss RIGScan CR49 development

Colon Cancer - Panel recommends testing system for colon cancer metastatic to the liver

Colon Cancer - V3D-Colon virtual colonoscopy outperforms competitors in study

Colorectal Cancer - Close postoperative follow-up is needed following colorectal cancer resection

Colorectal Cancer - Pharmaceutical company announces in-licensing of colorectal cancer drug

Colorectal Cancer - Promising new trial investigates colorectal cancer

Complementary & Alternative Medicine - Green tea finds a tumor cell

Complementary & Alternative Medicine - Many women find homeopathic remedies resolve menopause-related symptoms

Complementary & Alternative Medicine - Study tests healing power of laughter

Complementary & Alternative Medicine - Team awarded grant to evaluate traditional Chinese medicine for cancer care

Complementary & Alternative Medicine - U.S. orders halt to sales of the supplement andro

Complementary & Alternative Medicine - Yoga offers tranquility for cancer patients

Congestive Heart Failure - Implanted defibrillator reduces heart failure deaths

Congestive Heart Failure - Multicenter trial compares three medications in patients with heart failure

Contraception - Antimycotics won't compromise the efficacy of contraceptive vaginal rings

Contraception - Denver branch of Catholic Charities cuts birth control insurance

Contraception - Essure approved for use by Planned Parenthood Federation of America

Contraception - Licensing agreement for fentanyl patch inked

Contraception - Nestorone-releasing implants offer women contraceptive protection

Contraception - Progestins mitigate thrombotic risk of contraceptive estrogens

Coronary Artery Disease - CARDIOsphere evaluated for diagnosing coronary artery disease

Coronary Artery Disease - Martin Leon to lead studies of Rubicon Filter

Correction - Nebraska aims to protect children from methamphetamine labs

Cosmetic Surgery - Positive results reported in phase III autologous cellular therapy study

Cosmetic Surgery - Study: U.S. cosmetic surgery products demand will reach $1.8 billion in 2007

Cough - Self-hypnosis is effective at quieting habit cough

Crohn Disease - Drug can heal, reduce recurrence of fistulas

Cytokines - Interleukin-4 inhibits preadipocyte proliferation

DNA Vaccine - Altering conditions of DNA immunization allows control of immune response

Decompression Sickness - Can exercise before diving prevent illness?

Dengue Fever - Epidemiology of dengue virus in French Guiana elucidated

Dengue Virus - Dengue virus receptor molecules isolated by affinity chromatography

Depression - Poor prognosis for depression linked to an autoimmune thyroid condition

Developmental Biology - Crucial brain development gene identified

Developmental Biology - Harm of prenatal exposure to secondhand smoke magnified for poor children

Developmental Biology - New method allows scientists to observe genes in action

Device Trends - Report: Coating technology is a key in the growth of the medical device sector

Diabetes - Company to advance LY519818 into phase III studies for type 2 diabetes

Diabetes - Pharmaceutical companies seek approval to market Exubera in Europe

Diabetes Pathogenesis - Apoptosis of insulin-secreting cells investigated

Diabetes Pathogenesis - Biotin enhances ATP synthesis in rat pancreatic islets

Diabetes Risk - Coffee drinking associated with reduced risk of diabetes

Diabetes Therapy - Hypoglycemic substance in Capsicum frutescens isolated

Diabetes Therapy - Sucanon production set to start

Diabetes Therapy - Vasopeptidase inhibition normalizes diabetic endothelial dysfunction

Diagnostic Imaging - Integrated analyses of tumor vessels and metabolism yield better data

Diagnostics - CT angiography and MDCT is a first-line tool for evaluating abdominal vessels

Diagnostics - Company intensifies testing of hepatitis B test kit

Diagnostics - Generex developing kit for early detection of type 1 diabetes in young children

Diagnostics - Genomics company enters license agreement for nucleic acid arrays

Diagnostics - Increased use of CT creates concerns about radiation exposure

Diagnostics - Multidetector CT scan permits systematic examination of the colon

Diagnostics - Recovery of radioactively labeled proteins from gels investigated

Diet & Fitness - Oklahoma Senate says no to restricting unhealthy vending snacks in schools

Diet & Nutrition - University of Tennessee gets $500,000 to help promote healthy eating habits

Diet &Nutrition - Former Atkins associate opens new health center

Diet &Nutrition - High-fiber Mexican-style diet improves dyslipidemia in type 2 diabetes

Diet &Nutrition - Vitamin D effects seasonal changes in serum 250HD levels in older women

Distribution Agreement - LSBC enters biomanufacturing and commercial distribution agreement

Distribution Agreement - Longport announces receipt of $525,000 distribution rights payment

Distribution Agreement - Maxxon announces worldwide marketing and distribution agreement

Drug Delivery - Company announces application for CE Mark for Prometra pump

Drug Delivery - New type of vesicle could approach capabilities of biological structures

Drug Development -  N6-substituted adenosine derivatives have antimalarial activity

Drug Development -  N,N'-spacer-linked oligomeric ergolines have antimalarial activity

Drug Development -  Wikstroemia indica biflavonoids active against drug-resistant Plasmodium

Drug Development - Agents derived from Central American medicine plants have antiprotozoal activity

Drug Development - Antimicrobial diflunisal hydrazide-hydrazones synthesized

Drug Development - Approval period for biopharmaceutical products comparable in U.S. and E.U.

Drug Development - Commercialization in drug development stage drives product success, study shows

Drug Development - Novel arylsulfonamides active against drug-resistant HIV

Drug Development - Novel piperidine-based CCR5 antagonists synthesized

Drug Development - Pertussis toxin B-oligomer is pleiotropic HIV Tat inhibitor

Drug Development - Resonance energy transfer monitors the delivery of angiogenic proteins

Drug Development - Selective inhibitors of mitochondrial F1 F0 ATP hydrolase synthesized

Drug Development - Thiolactomycin analogues show promise as antimalarial, antitrypanosomal agents

Drug Discovery - Biopharmaceutical company announces successful drug discovery collaboration

Drug Discovery - Drug discovery company announces expansion of strategic alliance

Drug Discovery - Harvard Bioscience completes acquisition

Drug Resistance -  N. gonorrhoeae protein mutant allows entry of antimicrobials

Drug Resistance -  Staphylococcus lentus gene encodes resistance to chloramphenicol

Drug Resistance - First VanB vancomycin-resistant Enterococcus faecium isolated in Spain

Drug Resistance - Ribosomes contribute to bacterial resistance against antibiotic

Dyslipidemia - Phase I trials for dyslipidemia drug commence in Canada

Edema - Dyrenium diuretic drug to be marketed to physicians online

Electronic Medical Records - CareCert electronic form processing agreement announced

Electronic Medical Records - Gamewood's EMR enhancements help with nephrology reimbursement

Electronic Patient Records - InforMedix selects healthcare IT veteran to roll out ePRO device

Electroporation Therapy - Head-and-neck cancer study to advance commercialization of the MedPulser

Employee-sponsored Health Insurance - Soaring costs prompt small firms to drop health benefits

Employer-sponsored Health Insurance - Businesses decry rising hospital costs in Maine

Employer-sponsored Health Insurance - General Motors says healthcare obligation hit $67.5 billion in 2003

Employer-sponsored Health Insurance - Self-insurance group sets legislative and regulatory agenda for 2004

Employer-sponsored Health Insurance - Senate bill would give small businesses government bargaining power

Endocrinology - Atypical protein kinase C is target of TC10 signaling pathways

Endocrinology - Chromogranin A offers vessels protection against TNF-alpha-induced leakage

Endocrinology - Lipid profiles are significantly related to bone mass in women and men

Endocrinology - Maternal melatonin is a selective regulator of fetal and neonatal cortisol

Endocrinology - Parathyroid hormone production diverges with surgical versus natural menopause

Endometriosis - New publication helps women get diagnosis and treatment they need

Environmental Health - Adsorption and clay-catalyzed degradation of erythromycin A reported

Environmental Health - Household activities increase exposure to particulate pollution

Environmental Health - Idaho house makes changes to field burning legislation

Environmental Health - Prenatal exposures to magnetic fields do not adversely affect murine fetuses

Environmental Health - U.S. EPA faulted for incorrect drinking water claims

Environmental Health - U.S. plans public health study on an Ohio power plant's emissions

Environmental Health - Washington, DC, to recheck schools with high lead levels

Enzymology - C-terminal Src kinase facilitates angiogenic sprouting and vascular remodeling

Enzymology - Protein kinase C negatively modulates integrin expression

Enzymology - The VEGFR 2 inhibitor SU1498 stimulates ERK kinase accumulation and inhibition

Epidemiology - Hepatitis C virus type 1 is the most prevalent genotype in central Italy

Erectile Dysfunction - Drug appears safe for some men with congestive heart failure

Erectile Dysfunction - Study shows use of Testim improves symptoms of ED, low libido

Esophageal Variceal Bleeding - New drug application submitted for Sanvar IR

Evolution Research - Brains of chimps, humans closely related in gene expression

Evolutionary Biology - Yeast geneticists get a 2-for-1 deal

Exercise - Post-workout natural anabolic activator available in chain nutrition stores

Eye Cancer - Rb protein's role in retina development is key to understanding retinoblastoma

Female Sexual Arousal Disorder - Company to launch Femprox clinical study in China

Female Sexual Arousal Disorder - Viagra clinical studies in women do not support regulatory filing

Femoral Head Necrosis - Nonvascularized bone grafting for femoral head necrosis avoids hip replacement

Fetal Diagnosis - Sonography accurately detects a case of choledochal cyst before birth

Finance - 22% increase in revenues reported by lab services company

Finance - American Stock Exchange lists common stock of generic drugs company

Finance - Australian biotech company receives second U.S. $3M milestone payment

Finance - Biomaterial developer reports 29% fourth quarter revenue increase

Finance - Bioscience company's shareholders authorize reverse stock split

Finance - Biosciences company reports $6.2M private equity placement

Finance - Biotech board approves conditional stock split

Finance - Biotech company announces exercise of underwriters' over-allotment option

Finance - Biotech company received Nasdaq delisting notice

Finance - Biotech company reports 28% revenue growth in Q4, 52% for the year

Finance - Biotech company reports fourth quarter earnings per share of $0.24

Finance - Biotechnology company completes sale of convertible debenture offering

Finance - Biotechnology company reports reduced net loss for 2003

Finance - Blue Cross and Blue Shield of North Carolina reports growth

Finance - Cancer diagnostics company closes round A funding

Finance - Cancer vaccine maker reports quarterly loss of $11.1M

Finance - Chairman enters into prearranged stock trading plan

Finance - Defibrillator maker reports revenue increase of 24%

Finance - Device company reports income of $0.26 per share

Finance - Device firm reports 13% increase in revenues

Finance - Device maker reports 16% growth in sales

Finance - Diagnostics company closes first round of debenture financing

Finance - Drug delivery company reports improved financial results

Finance - Drug delivery company's revenues up 61%

Finance - Drug-delivery company raises $1.764 million through private placements

Finance - Factive maker reports net losses for fourth quarter and fiscal year 2003

Finance - Generic drug maker reports earnings of $0.32 per share

Finance - Generics company completes sale of $400M of 1.5% senior convertible notes

Finance - HMS Holdings Corp. announces profitable fourth quarter and fiscal year 2003

Finance - HealthGate Data Corp. reports $1.4 million loss in 2003

Finance - Healthcare-products company reports fourth quarter diluted EPS of $0.79

Finance - Imaging firm terminates reporting obligation, stock registration

Finance - Immunotherapy company announces net losses for quarter, year

Finance - Instrumentation company reports strong sales

Finance - Insulin-delivery company attracts $35.5 million in financing

Finance - Lifestyle-drug-focused biotech announces 3-for-2 forward split

Finance - MIM reaches tentative agreement with founder; settlement to be recorded in Q4

Finance - Maker of products for newborns announces profitable third quarter

Finance - Medical device company enters definitive agreements for $6M private placement

Finance - Medical-products maker reports increase in sales and revenues for Q4 and year

Finance - Molecular diagnostics company announces $34 million common stock sale

Finance - NIH grant awarded to expand development of antianthrax antibodies

Finance - OTC pharmaceuticals firm reports 15% increase in sales

Finance - Odyssey reports annual revenue increases 41%; net income increases 48%

Finance - Ophthalmic products manufacturer reports 2003 financial results

Finance - Orthopedics company reports record revenue and operating income for Q4

Finance - PPO introduces financial services product

Finance - Pain relief company closes on $5 million financing

Finance - Pharmaceutical company announces $34M private placement

Finance - Pharmaceutical company announces 2003 financial results

Finance - Pharmaceutical company announces series A preferred financing

Finance - Pharmaceutical company files for initial public offering

Finance - Pharmaceutical company files registration statement for IPO

Finance - Pharmaceutical company reports 2003 financial results

Finance - Pharmaceutical company reports annual sales increase of 103%

Finance - Pharmaceutical company reports loss of $0.85 per share

Finance - ProCyte announces 2003 financial results

Finance - Proposed offering of convertible senior notes announced

Finance - Record revenues for fourth quarter produce first quarter of profits in company

Finance - SRI/Surgical Express, Inc., reports 2003 financial results

Finance - Schroder leads $10.2M venture capital financing

Finance - Specialty pharmaceutical company closes $25.8M round of financing

Finance - Specialty pharmaceutical company reports net loss

Finance - Specialty pharmacy completes $150 million credit facility

Finance - State-supervised rehabilitation ends for insurance company

Finance - Therapeutics company announces closing of $57.7M common share offering

Finance - U.S. Physical Therapy announces 2003 financial results

Finance - Unilens reports improved operating results

Fitness - Inviting neighborhoods encourage exercise

Fitness - Poor diet, physical inactivity may soon overtake tobacco as leading cause of death

Food-borne Illness - Fresh garlic, semi-dried tomatoes linked to Salmonella Virchow spread

Food-borne Illness - Indicator organisms for safety and quality reviewed

Food-borne Illness - Method to confirm chloramphenicol in seafood validated

Food-borne Illness - Method to determine putrescine and cadaverine in shrimp developed

Food-borne Illness - Report: FDA needs seafood safety fixes

Fraser Syndrome - Link found between the protein GRIP1 and Fraser syndrome protein Fras1

Friedreich Ataxia - Faulty DNA replication linked to neurological diseases

Funding - M.D. Anderson Cancer Center receives historical $25 million gift

Funding - Maryland, Johns Hopkins Health System receive millions in federal grants

Gastric Cancer - Gastric cancer patients benefit from combined, intermittent chemotherapy

Gastric Ulcer - Prevacid NapraPAC available in U.S.

Gastroenterology Vaccine - Progress made in vaccines against gastrointestinal helminth parasites

Gene Expression Analysis - RNAi, siRNA educational website launched

Gene Silencing - DNA-delivered RNAi products launched for research applications

Generic Drugs - FDA approves generic version of Claritin-D 24-Hour

Genomics - Molecular Staging provides whole genome amplification technology

Genomics & Genetics - Cardiac troponin I mutation linked to idiopathic dilated cardiomyopathy

Genomics & Genetics - Gene for vitamin K epoxide reductase identified

Genomics & Genetics - X-linked gene elements leave women vulnerable to primary biliary cirrhosis

Genomics Toolkit - Collection of functional gene knockouts in a multicellular organism published

Genotyping - Diagnostics company launches high-speed genotyping service

Geriatrics - Clinicians need better tools for identifying people at risk for fracture

Geriatrics - Obesity could wipe out older Americans' health gains

Geriatrics - Researcher reports on key antioxidant to slow aging

Geriatrics - Tennessee orders admissions halted at nursing home

Gout - Study clarifies impact of diet on the risk of gout

Gynecologic Cancer - Researchers evaluate the clinical needs of patients after pelvic exenteration

Gynecologic Cancer - Whole-body PET/CT enables greater detection of active gynecologic cancers

Gynecology - Ovarian cancer cells regain more normal phenotypes with simultaneous therapy

Gynecology - Steroid hormones are strong regulators of vaginal tissue contractility

Gynecology - Sublingual misoprostol is better than oral delivery for cervical priming

Gynecology - Tumor angiogenesis has no predictive value for epithelial ovarian cancer

HIPAA - National medical privacy law makes health research harder, more expensive

HIPAA Compliance - HMSA selects CA eTrust solutions to help with HIPAA compliance

HIV Diagnosis - CDC reports that OraQuick test produces fewer false positive HIV-1 results

HIV Therapy - IND filed with FDA for phase Ib/IIa trials for HIV viral entry inhibitor

HIV/AIDS - FDA authorizes a clinical study with Alferon LDO for HIV

HIV/AIDS - HIV/AIDS incidence rising faster among women in Mekong region than men

HIV/AIDS - Serostim decreases visceral adipose tissue in HARS patients, study shows

HIV/AIDS - Southern states cautioned to keep tabs on HIV outbreaks among college students

HIV/AIDS - U.S. senator pushes AIDS compensation for veteran families

HIV/AIDS - U.S., U.N. launch anti-AIDS project for army in Tajikistan

HIV/AIDS - Worldwide HIV/AIDS cases rising for women

HIV/AIDS Cancer - AIDS-associated oral plasmablastic lymphomas linked to HHV8, EBV infection

HIV/AIDS Dementia - CXCR4 mediates gp120 neurotoxicity in cerebellar granule cells

HIV/AIDS Dementia - Cocaine-enhanced gp120-induced neurodegeneration mediated by iNOS

HIV/AIDS Diagnostics - Incomplete peptide dissolution can lead to false-positive ELISPOT results

HIV/AIDS Drug Resistance - Crystal structures of NNRT-resistant HIV RT characterized

HIV/AIDS Epidemiology - HIV test interval information useful in progression studies

HIV/AIDS Epidemiology - Ottawa HIV "superinfection" case did not carry superinfection

HIV/AIDS Gene Therapy - Novel anti-HIV lentiviral vector efficiently selects transduced stem cells

HIV/AIDS Immune Control - TRIM5alpha restricts HIV infection in Old World monkeys

HIV/AIDS Pathogenesis - HIV matrix serine phosphorylation in early postentry replication clarified

HIV/AIDS Perinatal Medicine - HIV coreceptor expression determined in exposed but uninfected infants

HIV/AIDS Proteomics - Assembly properties of HIV CA protein determined

HIV/AIDS Proteomics - Effects of P-TEFb on HIV transcription elucidated

HIV/AIDS Proteomics - HIV Vif protein post-translationally modified by ubiquitin

HIV/AIDS Proteomics - Protease activity regulates Env-mediated membrane fusion

HIV/AIDS Proteomics - Tat from HIV subtype C has impaired chemotactic ability

HIV/AIDS RNA Research - Perinuclear HIV RNA release mediated by hRIP

HIV/AIDS RNA Studies - Antisense oligonucleotide scanning arrays reveal novel HIV leader RNA foldings

HIV/AIDS Therapy - Emtricitabine is option for once-daily antiretroviral therapy

HIV/AIDS Therapy - Protease inhibitors can induce lactic acidosis

HIV/AIDS Transmission - Medical injections do not spread HIV in rural Uganda

HIV/AIDS Treatment - Nigeria's AIDS treatment program back on track

HIV/AIDS Vaccine - HIV-1 Nef delivery to dendritic cells may stimulate immune response

HIV/AIDS Vaccine - HIV-neutralizing antibody fragment isolated from lupus library

Head & Neck Cancer - Angiogenic protein marks oral squamous cell carcinoma prognosis

Head & Neck Cancer - Interim data announced for Xcytrin and concurrent chemoradiation trial

Head & Neck Cancer - TNP-470 diminishes tongue cancer growth and lymphatic invasion in study models

Health Care - Regency Hospital Company announces long term acute care hospital

Healthcare & Politics - Australia's government announces major funds injection into healthcare

Healthcare & Politics - United HealthCare leads Minnesota in soft money donations

Healthcare & Politics - Vermont senate gives preliminary approval to hospital whistleblower bill

Healthcare Access - Detroit nursing facility offers compassionate care for uninsured

Healthcare Access - Medical benefits extended to employees' domestic partners in Tampa

Healthcare Access - Missouri committee votes to keep health labs open

Healthcare Access - New veterans' clinic to open in Mississippi

Healthcare Access - Termination of contract could hurt Phoenix-area Medicaid patients

Healthcare Benefits - Georgia insurer establishes high-deductible health plans compatible with HSAs

Healthcare Benefits - Insurer combines health, disability management for employer plans

Healthcare Benefits - Uninsured not willing to pay what it costs to insure themselves, economist says

Healthcare Coverage - Healthcare corporation to implement discounts for uninsured patients

Healthcare Coverage - Kryptiq unveils new solution for managing healthcare insurance contracts

Healthcare Coverage - Louisiana lawmakers looking again at insurance plans for the poor

Healthcare Coverage - Magellan Health Services awarded contract for Iowa Medicaid program

Healthcare Coverage - New Mexico's governor signs AFSCME contract, health bill

Healthcare Coverage - Premera Blue Cross and Molina Healthcare of Washington announce agreement

Healthcare Economics - Northwest U.S. businesses' healthcare costs predicted to rise 14% this year

Healthcare Economics - Prescription drugs inflation down from 6.2% to 2.2% in just over 2 years

Healthcare Economics - Rhode Island has highest insurance premiums in U.S., study says

Healthcare Economics - Rising cost of healthcare premiums may slow in North Carolina

Healthcare Fraud - Healthcare group proposes plan to fight unlicensed insurance scams

Healthcare Practice - General practitioners are more likely to prescribe technical aids to women

Healthcare Spending - Hospital CFOs predict double-digit increase in capital spending

Heart Disease - Study: Cholesterol lowering with atorvastatin halts progression of heart disease

Cardiology - High heart rate reduces arterial distensibility

Cardiology - AT2 -receptor antagonists block Ang II effects on atrial noradrenaline release

Candidiasis - Protease-inhibitor cocktail protects, increases antimicrobial action of new peptide

Candidiasis - New peptide derived from protein in saliva may be promising antifungal agent

Cancer Therapy - Spacer-containing doxorubicin prodrugs limit tumors without systemic toxicity

Cancer Vaccine - CG motifs in virus-like particles induce cytotoxic T cell responses

Cancer Therapy - Semaphorin-3F curtails tumor angiogenesis

Cancer Therapy - Polo-like kinase 1 is a viable target for the treatment of prostate cancer

Cancer Therapy - Higher doses would make taxane-mediated antiangiogenesis more effective

Cancer Therapy - First KOS-862 phase Ib chemotherapy combination trial begins

Cancer Therapy - Decoy receptor 3 can be suppressed to staunch tumor angiogenesis

Cancer Research - Movies of cells capture transmission of messages that control genes

Cancer Prevention - Advocacy group to accelerate the attack on cancer

Cancer Outcomes - New statistics show poverty gap in cancer survival has widened

Cancer - Pharmaceutical company provides update on second-generation TAPET vectors

Cancer Metastasis - Platelet-activating factor boosts the activation of proangiogenic cytokines

Cancer - FDA-approved X-ray imaging accessory to aid in image-guided cancer treatment

Cancer - Biopharmaceutical companies announce antibody collaboration

Cadaver Research - UCLA halts corpse donations until body part selling investigation is complete

Business Update - Wheelchair maker enters North American market

Business Update - Wellbutrin maker provides updated 2004 guidance

Business Update - Specialty insurance companies announce five-state renewal rights transaction

Business Update - Johnson & Johnson CEO's bonus jumped by more than half in 2003

Business Update - National Medicaid service provider buys Michigan Medicaid managed care plan

Business Update - Insurer offers new 3500 Deductible PPO Plan with no copays, coinsurance

Business Update - Initiate Systems provides fourth quarter healthcare-practice update

Business Update - HMO upgrades management software to offer members broader products, services

Business Update - Healthcare lobby group changes name

Business Update - Firm combines gene expression, proteomics and reagents businesses

Business Update - Delaware commissioner mulls dissolution of insurer affiliation

Business Update - American Retirement Corporation cooperates in Medicare probe

Business & Finance - WebMD reports increased fourth quarter revenue

Business & Finance - South Dakota state agency gets more funds for anti-tobacco efforts

Business & Finance - Rhode Island Governor creates a central Office of Health and Human Services

Business & Finance - Pharmaceutical company makes significant strides in 2003

Business & Finance - Pharmaceutical company announces vitamin E contract

Business & Finance - Pharmaceutical company enters agreement to sell MVI product business

Business & Finance - Network of rehabilitation providers posts $162 million in national claims

Business & Finance - Montana coalition proposes increasing tobacco taxes

Business & Finance - Kaiser achieves operating margin of 3.9%, announces upgrades

Business & Finance - Genetic research planned at Cincinnati's new $115 million research facility

Business & Finance - Hawaiian insurer reports $10.8 million profit, but still pushes rate hike

Business & Finance - EPA awards contract for development of anthrax decontamination product

Business & Finance - Drug development services provider expands facility and increases credit line

Business & Finance - Drug development company announces reduced loan principal

Business & Finance - Company opens new sales office in India for SLICES and distribution of shares

Business & Finance - Dermatology company emerges from Chapter 11 protection with new owners

Business & Finance - Biosciences company updates stock plan, gets patent

Business & Finance - Cigarette tax discussed by Kentucky farmers, health advocates

Business & Finance - Audit criticizes Hawaii Health Department's financial practices

Breast Implants - Implant products receive full EU Class III medical device certification

Business & Finance - Antibody company files for initial public offering

Breast Cancer - Women with familial cancer risk understand risk of prophylactic mastectomy

Breast Cancer - Variance exists in confidant and breast cancer patient reports of QOL issues

Breast Cancer - Study: Self exam increases women's concerns, has no effect on mortality

Breast Cancer - Patients switched from tamoxifen to exemestane more likely to stay cancer-free

Breast Cancer - Radiologists with higher mammogram "recall rates" find more early cancers

Breast Cancer - Estrogen interacts with estrogen receptor and SP proteins to control VEGF

Breast Cancer - Fulvestrant gains E.U. marketing approval

Breast Cancer - Eating habits early in life may affect cancer risk

Breast Cancer - Black women in U.S. more likely to have delayed diagnosis, treatment

Brain Tumors - Soluble factors from glioblastoma cells can disrupt the blood-brain barrier

Brain Tumors - Proton therapy offers advantages for children with brain tumors, study shows

Brain Cancer - IL-2-activated NK cells enhance effect of tumor vaccine in brain cancer

Bovine Spongiform Encephalopathy - Projections of beef production drop following mad cow disease scare

Avian Influenza - Avian flu threat prompts poultry group to cancel banquet

Awards - Medical device company announces internationally received awards

Awards - Technology company receives award for pharmaceutical automated sales tool

Bacillus - Method to identify protease genes from B. thuringiensis developed

Bacteriology - Acyl-homoserine lactone binding in Vibrio fischeri is reversible

Bacteriology - YefM antitoxin family carries novel antibacterial target

Benign Prostatic Hyperplasia - Uroxatral marketed in U.S. for benign prostatic hyperplasia

Bioengineering - The biosurfactant MEL-A cultivates vigorous liposomal transfection

Bioprostheses - Mosaic and Freestyle porcine-tissue heart valves reintroduced in Japan

Biosecurity - HHS will lead effort to enhance bioterror research in "dual use" funding

Biotechnology - Peptide array used to identify Ang II inhibitory peptide

Biotechnology - SdFFF system aids study of PFC emulsion particle stability

Bioterrorism - NIOSH approves mask for protection from biological, chemical, and nuclear attack

Body Composition - A large-sample QTL study in mice examined body composition

Bone Loss - Low vitamin B-12 levels linked to bone loss in older women

Bone Tumors - Cross-pin fixation helps maintain the stability of endoprosthetic stems

Parkinson Disease - Disposition of 1,2,3,4,-tetrahydroisoquinoline in rat brain reported

Partner Abuse - Nurses urged to increase safety-promoting behaviors of abused women

Patents - Additional patent granted on phenotype microarray technology

Patents - Company receives third ISA247 patent

Patents - Donation of patents may accelerate new treatment for global health problem

Patents - Preliminary injunction relating to Tannate 12d S will delay initial shipments

Patents - Tissue engineering company announces approval of Canadian patent

Patient Monitoring - FDA clears monitoring system

Patient Privacy - Group testifies against creating database of the disabled

Patient Privacy - Minnesota senate panel blocks bill to repeal parental notice law

Patient Privacy - New Mexico hospital criticized for patient information handling

Patient Safety - Care of patients who transition across healthcare settings needs improvement

Pediatric Epidemiology - Community issues diminish the effects of IMCI on infant mortality in India

Pediatric HIV/AIDS - HLA-A2-restricted anti-Nef CD8 cell response limited in children

Pediatric Obesity - America's teens are growing up and out

Pediatric Obesity - Dairy, moderate fat, carbohydrate intakes reduce obesity in young teens

Pediatric Obesity - Problems controlling anger lead to weight gain for teens

Pediatrics - Clinical judgment as good as guidelines for treating febrile infants

Pediatrics - Most preterm infants in Brazil need preventive antimicrobials

Pelvic Cancer - Genitourinary complications of pelvic radiation therapy can be severe

Peripheral Neuropathy - Sensory impairments from peripheral neuropathy improve in Anodyne study

Personnel - Aetna chief financial officer joins ophthalmology company board of directors

Personnel - Andrew M. Clarkson and J. Kenneth Glass join board of men's health company

Personnel - Ashley Bush signs 10-year consultancy agreement with biotech firm

Personnel - Baptist Health System chairman resigns

Personnel - Biomaterials company announces new vice president of sales

Personnel - Bioscience company appoints new chairman

Personnel - Biotech company reports board changes, new governance structure

Personnel - Biotechnology company elects Eric H. Bjerkholt to board of directors

Personnel - Canadian biotech company announces CFO change

Personnel - Carroll named chief business officer at firm developing nanofluidic systems

Personnel - Chief financial officer John McCarthy leaves genomics firm

Personnel - Consumer health organization names new chairman of the board

Personnel - DNA-test provider appoints experts to its medical advisory board

Personnel - Daniel Wiens named executive VP of operations, MED3OOO Group, Inc.

Personnel - Device company names new board member

Personnel - Device firm names new members of management, board

Personnel - Drug-discovery company names new CEO

Personnel - Genomics company appoints Paulette Dillon chief business officer

Personnel - Genomics company appoints financial expert to board of directors

Personnel - Glycoprotein company makes development appointment, opens new office

Personnel - Healthcare company announces new member of board of directors

Personnel - Jacque J. Sokolov, MD, named to MedCath board

Personnel - Joseph C. Connors, general counsel, plans to leave company.

Personnel - Joseph Harris named to board of EndoVenous laser treatment maker

Personnel - Leon E. Rosenberg, MD, joins biopharma's board

Personnel - Medical device manufacturer appoints new medical director

Personnel - Medical investment company appoints new member to its board of directors

Personnel - Medical technology company elects new board member

Personnel - Montgomery named VP of business development at pharmaceutical firm

Personnel - Neonatologist to join Pediatrix as vice president, research and education

Personnel - New Center for Medicare Management administrator named

Personnel - New chief administrative officer named for South Pointe Hospital

Personnel - New leader named for Nebraska's Health and Human Services Department

Personnel - Northwestern Memorial names Patrick McCarthy as chief of cardiac surgery

Personnel - Obourn named senior VP at health insurance firm

Personnel - Papadopoulos named to board of directors at genomics firm

Personnel - Pharmaceutical company announces new members of scientific advisory board

Personnel - Pharmaceuticals company announces new scientific advisory board members

Personnel - Pharmacy benefits management company names new vice president, customer care

Personnel - Plattner named head of research at anti-infectives pharmaceutical firm

Personnel - Promotion, appointment of regulatory affairs post reported at drug firm

Personnel - Protein therapeutics company adds to senior management team

Personnel - Research-based startup names first chief executive officer

Personnel - Spitz named marketing and sales VP at drug delivery firm

Personnel - VitalWorks appoints new member to board of directors

Pharmaceutical & Drug Development - Intestinal solute carriers improve oral drug absorption

Pharmaceutical & Drug Development - Microwave accelerated oligonucleotide labeling expands research possibilities

Pharmaceutical & Drug Development - Peptide ester conjugates for ester prodrug stability developed

Phytohormone - Newly discovered 8-prenylnaringenin is a strong angiogenesis inhibitor

Prescription Drug Benefits - United Methodist Church offers discounts on prescription medications

Preventive Medicine - Panel discusses new "before-onset care" paradigm

Prion Disease - Fibroblast cell lines susceptible to TSE agents

Privacy Issues - Judge denies request for abortion records

Professional Training - Insurer announces $3 million in nurse training scholarships

Prostate Cancer - Active surveillance is a new management strategy for early prostate cancer

Prostate Cancer - Finasteride adversely affects the early diagnosis of prostate cancer

Prostate Cancer - Metastasis-associated protein 1 signals prostate cancer progression

Prostate Cancer - Misonix to distribute prostate cancer product in Europe

Prostate Cancer - Peptide vaccine helpful for HLA-A2-positive patients with prostate cancer

Prostate Cancer - Testing could better select patients for prostate-related radiation treatments

Prostate Cancer - VEGF plays a fundamental role in the promotion of osteoblastic metastasis

Protein Expression - Multi-affinity tag system to produce proteins in E. coli developed

Protein Mapping - Protein-protein interaction map of virulence-related genes published

Proteomics - Antithrombins suppress angiogenesis by down-regulating perlecan

Proteomics - Formin induces nucleation of actin filaments

Proteomics - Gene structure new member of Tieg family of proteins reported

Proteomics - Integrated lysis and affinity purification plates introduced

Proteomics - Ku86 deficiency reduces intrachromosomal homologous recombination

Proteomics - Tumor endothelial marker 8 interactions mediate tumor angiogenesis

Psychology - The Jefferson Scale of Physician Empathy is a reliable tool for assessing nurses

Public Health - AAA chief urges treating highway crashes as public heath epidemic

Public-Employee Health Insurance - Albuquerque city employees on military duty receive insurance warnings

Pulmonary Fibrosis - Study links lung disease with heart problems

Pulmonary Medicine - Excess placenta growth factor exacerbates pulmonary emphysema

Pulmonary Medicine - VEGF and proteolytic enzyme show a strong correlation with pleural effusions

Quality Assurance - Insurance complaints in Oregon for second year

Quality Assurance - STAT Care Inc. announces clinical software to reduce ER medical error risk

Quality Assurance - Stark differences in care revealed at top U.S. hospitals

Quality Assurance - Strategic alliance helps health plans monitor quality of network care

Radiation Therapy - Long-term risks of medical radiation often ignored

Radiology Resources - Cardiac imaging digital community launched

Rankings - Diagnostics company named best in people development by Training magazine

Rankings - MRI systems manufacturer named Boston area's fastest growing private company

Receptor Studies - G-protein coupled receptors in neuroendocrine pathways are oligomeric

Receptor Studies - ORL1 receptor modulation of calcium channels is agonist-independent

Regenerative Medicine - Interest in regenerative medicine heats up

Regulatory Issues - 'Certificate of Need' laws lead to improved patient outcomes for some procedures

Reimbursement - AMA panel agrees to establish Category I CPT code for Essure

Removable Stent - Stent maker receives regulatory clearance for benign indication

Renal Disease - HCV elicits abnormal immunology in a patient with kidney disease

Reproductive Biology - Finding refutes doctrine of a finite supply of eggs in mammals

Reproductive Medicine - Ovarian tissue transplant in monkey may hold promise for cancer survivors

Reproductive Medicine - Transcription factor required for lamina propria differentiation

Research Funding - Florida Governor approves $30 million for medical research

Respiratory Medicine - LTB4 promotes neutrophil recruitment to inflamed pleural space

Respiratory Therapy - Rotech Healthcare announces new agreements with Gentiva Health Services

Restenosis - FDA approval granted for Taxus Express2 paclitaxel-eluting stent system

Revision Hip Arthroplasty - Impacted cancellous graft added to cement in hip revision restores bone stock

Rheumatoid Arthritis - Lipid peroxidation decreased in patients with rheumatoid arthritis

Rheumatology - Interleukin gene therapy expands options for treating osteoarthritis

Rotavirus Vaccine - HIV-1 Tat peptide-rotavirus enterotoxin protein stimulates immune response

SARS - Company announces discovery of compound for the potential SARS treatment

SARS - Hong Kong health chief apologizes over SARS crisis handling

SARS - Hong Kong may drop some control measures against SARS

SARS - SARS without pneumonia could be common in outbreak areas

Schistosomiasis - IL-12 enhances immunity of Schistosoma mansoni fatty acid-binding protein

Schizophrenia - Brain model enhances understanding of schizophrenia

Schizophrenia - Impaired AKT1-GSK3 beta signaling plays role in schizophrenia

Sealant System - Trial completed on CryoSeal system in Japan

Sepsis - Inhibition of myocardial cytochrome C oxidase involved in sepsis

Sex Education - Health advocates rally against abstinence-only plan

Sexual & Reproductive Health - Patient demographics and provider differences affect abortion outcomes

Sexual & Reproductive Health - Pledging abstinence does not reduce teen STD rate, study finds

Sexual & Reproductive Health - Previous Chlamydia trachomatis infections adversely affect male fertility

Sexual & Reproductive Health - Research shows growing challenges in controlling STDs among gay and bisexual men

Sexual & Reproductive Health - Scientists defend government-funded sex health studies

Sexually Transmitted Diseases - Bush Administration weighs condom warning

Skin Cancer - Reconstructive surgery improves appearance, outcomes for patients

Skin Cancer - Topical celecoxib treatment can inhibit acute oxidative tissue damage

Sleep Apnea - New medical device company to focus on obstructive sleep apnea

Small-Cell Lung Cancer - Vinorelbine plus doxorubicin in relapsed small-cell lung cancer is highly toxic

Smallpox - Clinical trial of smallpox vaccines to be conducted in St. Louis

Smallpox - New inoculations show promise

Smallpox - Recommendations issued on development of drugs for vaccine side effects

Smoking Ban - New York health department studying effects of smoking ban on employees

Smoking Cessation - New drug helps smokers quit while limiting post-cessation weight gain

Spinal Surgery - Abington Memorial Hospital orthopedists testing new surgical materials

Spinal Surgery - Motor evoked potentials are improved by double-train electrical stimulation

Sports Medicine - Hormone supplement used by athletes may not increase testosterone

Staffing - MT Ultimate Healthcare signs with CABS Nursing Home

Staph Infections - Altastaph receives FDA fast track designation

State Medicaid - Budget tug-of-war threatens Medicaid program funding in Georgia

State Medicaid - Florida KidCare bill signed, removing 90,000 kids from waiting list

State Medicaid - Governor looks to university medical center to help reform TennCare

Stem-Cell Research - Endothelial progenitor cells are detected in infantile hemangioma

Stem-Cell Research - Four-color immunofluorescence enables mesenchymal stem cell identification

Stem-Cell Research - New human embryonic cell lines to be made available to researchers

Stem-Cell Research - OLIG2 inhibits astrocyte differentiation

Stem-Cell Research - Olfactory bulb neural stem cells lack hematopoietic potential

Stem-Cell Research - PU.1 supports proliferation of immature erythroid progenitors

Stem-Cell Research - SOCS3 negatively regulates granulopoiesis and G-CSF receptor signaling

Stem-Cell Research - TRAIL regulates erythroid maturation via ERK signaling

Stem-Cell Research - U.S. lawmakers want to ease stem cell research restrictions

Stem-Cell Research - Verotoxin and IFN-alpha have synergistic effect on erythropoiesis

Stem-Cell Transplantation - Fetal cytokine production during MLRs determined

Stem-Cell Transplantation - RIC SCT feasible for patients with advanced solid tumors

Stem-Cell Transplantation - Treosulfan-fludarabine conditioning regimen safe and effective

Stomach Ulcers - New 10-minute test for ulcer screening introduced

Stroke - Association tools help hospitals improve stroke care

Stroke - Early treatment confirmed as key to stroke recovery

Stroke - Folic acid fortification may have lowered stroke deaths

Stroke - Lack of awareness about stroke hinders use of life-saving drugs

Stroke - Neuroendovascular intervention shows promise for greater stroke patient outcomes

Stroke Epidemiology - Rural South Africa faces stroke crisis similar to affluent Western countries

Stroke Rehabilitation - Arm stimulation soon after stroke improves function years later

Substance Abuse - Inhalant abuse among younger children rising; new campaign announced

Surgery - Surgical training should be emphasized in gynecologic oncology fellowship

Thyroid Cancer - SAGE identifies genes that are differentially expressed in thyroid carcinoma

Thyroid Disease - Thyroid radiation doses "too high"

Tick-borne Disease - Antibodies to tick salivary antigens detected in patients from Spain

Tick-borne Disease - Cases of spotted fever rickettsioses in U.S. travelers summarized

Total Hip Arthroplasty - Alumina-on-alumina hip arthroplasty is effective in young patients

Total Hip Arthroplasty - Computer simulation improves preoperative planning for total hip replacement

Total Hip Arthroplasty - Fractures of ceramic bearings in total hip arthroplasty occur infrequently

Total Hip Arthroplasty - Large femoral canals and Type IV defects should not receive longer stems

Total Hip Arthroplasty - New, two-incision approach to total hip arthroplasty is described

Total Hip Arthroplasty - Stress shielding after porous-coated THA is not problematic

Total Hip Arthroplasty - The Charnley classification is the best predictor of THA long-term success

Total Joint Implants - One-dimensional porous hydroxyapatite is useful to evaluate bone ingrowth

Transfusion Medicine - Effects of cryopreservation on cord blood cell immunogenicity determined

Transplant Medicine - Depression is less common among married transplant recipients

Transplant Medicine - Living donor liver transplantations face technical challenges

Transplant Medicine - Mediastinal stiffening and chest wall scarring can restrict lung inflation

Transplant Medicine - Miniaturized heart pump for children approved by FDA

Transplant Medicine - New children's heart pump may save lives

Transplant Medicine - Percutaneous dilational tracheotomy is effective in solid-organ transplantation

Transplant Medicine - Study shows recipients' livers grow more than donors'

Transplant Medicine - Transplantation of tissues enhances quality of life in many patients

Tropical Medicine - Congenital Trypanosoma cruzi abounds in Bolivia despite reduced poverty

Tuberculosis - Biotechnology company licenses gene target identification technology

Tuberculosis - TB often underlies cervical lymphadenopathies in Mexican women

Tuberculosis - Tuberculosis cases increased in South Dakota in 2003

Tuberculosis - Unique proteins identified in Mycobacterium tuberculosis

Tuberculosis Diagnostics - Bactec MGIT 960 provides accurate TB drug resistance profiles

Tuberculosis Enzymology - Structural features of M. tuberculosis AKmt identified

Tuberculosis Enzymology - Structure of M. tuberculosis RpiB characterized

Tuberculosis Epidemiology - Factors linked to TB clustering in Spain identified

Tuberculosis Pathogenesis - STAT1 plays key role in defense against pulmonary TB in mice

Tuberculosis Proteomics - Structure of M. tuberculosis MPT51 protein characterized

Tuberculosis Therapy - Fast-flow EPR spectroscopy enables observation of isoniazid hydrazyl radical

Tuberculosis Therapy - Location of M. tuberculosis KatG radical formation identified

Tuberculosis Vaccine - Prospects for new tuberculosis vaccines reviewed

Tumor Classification - New system combines molecular biology and classic pathology

Type 2 Diabetes Pathogenesis - Reducing oxidative stress improves glycemic control in type 2 diabetes

Type 2 Diabetes Therapy - Protein tyrosine phosphatase inhibitor acts as antihyperglycemic agent

Urinary Incontinence - Bladder neck mobility increases the odds for post-pregnancy stress incontinence

Vaccine Development - Acetyl and phosphate groups quantified in vaccine polysaccharides

Vaccine Efficacy - Diphtheria-tetanus-pertussis vaccine booster effective in adults

Vector Development - Expression of exogenous genes in Trypanosoma cruzi improved

Vector Development - Lentiviral vector encoding NY-ESO-1 induces effective CTL response

Vector Development - Silk-elastin-like hydrogels convey genes to human cancer cells

Veteran Care - Donation accepted to build veterans clinic in Sumter County, Florida

Virology - A new continuous nonradioactive assay monitors RNA polymerase activity

Virology - Harmless virus associated with longer life for some HIV-positive men

Virology - Human TT virus variants may be associated with pathology

Virology - Key steps optimize the propagation of gene deleted Sendai virus vectors

Virology - Two-step purification confirms that RNA viruses replicate within RNP complexes

Weight Loss - Doctor's statement reveals dark side of low-carb diets

Weight Reduction - Group calls for comprehensive solutions to help reduce obesity

West Nile Virus - U.S. CDC warns Oregon could be hit with West Nile this summer

West Nile Virus - Virus is blamed on hybrid mosquito

Women's Health - AHA responds to findings from Women's Health Initiative

Women's Health - Brazil announces health, domestic violence measures

Women's Health - Chemo improves survival after cryoreductive surgery for ovarian, peritoneal cancer

Women's Health - Genetics may play part in miscarriages

Women's Health - Rape exploits women's increased vulnerability to HIV infection

Wound Care - Skin substitutes and wound healing reviewed

siRNA Targeting - siGENOME siRNA targets entire human genome

Parainfluenza Vaccine - Parainfluenza type 3 vaccine safe and effective in children

Palliative Care - Hawaii house tables measure on 'death with dignity' proposal

Pain Medicine - Drug safe and effective for the elderly

Ovarian Cancer - Combo paclitaxel/carboplatin is effective as second-line ovarian cancer therapy

Osteoporosis - When combined, alendronate and HRT have no added benefit for gaining bone mass

Osteoporosis - Vertebral fractures are under-reported in elderly patients

Osteoporosis - Risedronate reduces nonvertebral fracture risk within 6 months of initiation

Osteoporosis - Premenopausal women show specific chromosomal links to bone mineral density

Osteoporosis - Research services company announces osteoporosis contract

Osteoporosis - MMP-9 gene changes associate with bone mineral density in men but not women

Osteoporosis - Hydrocortisone increases the differentiation rate of human osteoblasts

Osteoporosis - Fitness and nutrition programs can reduce osteoporosis risk, doctor advises

Osteoporosis - Estrogen receptor genotypes explain perimenopausal bone loss rates

Osteoporosis - Assessments of medieval bones show activity mitigates osteoporotic fracture

Osteomyelitis - Acceptable treatment failure rates of osteomyelitis in diabetes listed

Orthopedics - FDA clears new biologic bone paste

Osteoarthritis - Clinical study confirms efficacy of Lyprinol in treating osteoarthritis

Orthopedics - Body composition associates with type of hip fracture among elderly women

Organ Donation - HIV patients could donate organs to others with the virus under Illinois bill

Organ Donation - Regulatory group seeks to caution living organ donors

Ophthalmology - Study documents incidence of and risk factors for dry eye in older people

Ophthalmology - Biochemical inhibitors may be able to prevent diabetic retinopathy

Oncology - Signals for c-erbB-2 and VEGF combine to assess breast cancer prognosis

Oncology - MMP-9 promoter screening could discern the value of cancer gene therapy

Oncology - C-Myc inhibition shows the potential for treating liver cancer

Oncogenesis - Protein tyrosine phosphatase gamma is a tumor suppressor gene in breast cancer

Oncogenes - Researchers find a protein that controls cell growth

Oligodontia - Missense mutation in PAX9 causes non-syndromic oligodontia

Obstetrics - The accuracy of reported preterm birth rates is questionable

Obstetrics - When lactation ends bones regenerate to prepare mothers for more reproduction

Obstetrics - Study finds abortion doesn't affect birth weight of future babies

Obstetrics - Mother-to-child transmissions of HTLV type I have fallen in Japan

Obstetrics - Fetal short femur length identifies babies at risk for skeletal dysplasias

Obesity Therapy - Web-based assessment tool targets bariatric surgery program analysis

Obesity Therapy - Exercise augments CB1-receptor inverse agonist effects on weight loss in mice

Obesity Therapy - 5-Hydroxy-L-tryptophan suppresses food intake in stressed rats

Obesity Epidemiology - Prevalence of obesity in southeast Spain increasing

Obesity Epidemiology - Obesity, diet, and physical activity in college students assessed

Obesity - Women with weight problems earn 30% less

Obesity - Iowa Senator vows to make obesity-related issues a top legislative priority

Obesity - Obesity could top smoking as No. 1 cause of preventable death in the U.S.

Nutrition - Parents need to set example by eating more fruit and vegetables

Nutrition - McDonald's stops super sizing and everyone pays attention

Nutrition - FDA to consider petition for more extensive health claims for calcium

Nursing Practices - Delnor-Community Hospital wins "magnet" designation from ANA

Nutrition - FDA gives favorable review for OmegaTech DHA

Nuclear Medicine - Company announces commercial availability of lutetium, rhenium

Non-Small Cell Lung Cancer - p53 gene mutations are found in exhaled breath condensate of NSCLC patients

Non-Hodgkin Lymphoma - Pivotal trial initiated for Pixantrone

Non-Hodgkin Lymphoma - Diets high in fat and animal protein linked to increased risk of lymph cancer

Non-Hodgkin Lymphoma - Long-term chemotherapy in children with NHL adversely affects teeth

Neurotoxin - Trimethyltin induces apoptosis via caspase activation in PC12 cells

Neuroscience - The symptoms of spinal cord infarction warrant caution in pregnant women

Neuroscience - Gender influences interhemispheric interconnectivity in the corpus callosum

Neuroscience - Erythropoietin cDNA protects rodent brains against hypoxia-ischemia

Neuroscience - A novel technique highlights the elements of early neuronal development

Neuroscience - Dopamine neurons mediate excitatory signals via glutamatergic synapses

Neurobiology - Neuroscience company raises $19.4 million in private equity financing

Myocardial Infarction - State-required continuing medical education does not affect heart attack care

Myocardial Infarction - State-required CME: No effect on heart attack care, boosts use of branded drugs

Myocardial Infarction - MCIP1 overexpression preserves post-infarction cardiac function

Myocardial Infarction - Hospitals following heart attack guidelines have better outcomes

Local Anesthetics - Company reports results of ENT-103 expanded preclinical testing

Lung Cancer - Adenovirus-mediated p53 expression uses other genes to stimulate apoptosis

Lung Cancer - Translational research seeks ways to avoid radiotherapy-induced lung toxicity

Lung Disease - EPA examines link between microwave popcorn and lung disease

Lupus Nephritis - New medicine offers hope to lupus patients with kidney disease

Lymphoid Cancer - European approval granted for once weekly NeoRecormon

Lymphoma Therapy - Post-SCT immunological recovery similar in CLL, NHL patients

Lymphoproliferative Disease - Reduced-intensity BEAM-alemtuzumab SCT effective

Macular Degeneration - Search for eye disease genes narrows

Macular Degeneration - Smoking linked to blindness

Malaria Drug Resistance - Crt and Mdr1 orthologues not involved in P. chabaudi chloroquine resistance

Malaria Therapy - ACT adherence low for pediatric patients in Zambia

Malaria Therapy - Mefloquine-artesunate effective for treating uncomplicated malaria

Malaria Transmission - No Plasmodium infection found in donated blood from Turkey

Male Pattern Baldness - Homspera deemed dermally nontoxic

Manufacturing Agreement - Ligand inks agreement for manufacturing and packaging of AVINZA

Market Analysis - Americans might be getting better deal on pharmaceuticals than Europeans

Market Analysis - Biotech was up nearly 2% in February

Market Analysis - Twenty-two year analysis shows overall media coverage of HIV/AIDS decreasing

Market Trends - Report: Key opinion leaders trend toward specialization

Medical Devices - Nonprofit medical device organization formed

Medical Errors - Analysis, biopsy of sarcomas should be done by experienced professionals

Medical Errors - New Mexico doctors face license loss

Medical Errors - Patients may have received wrong results for HIV, hepatitis tests

Medical Errors - Talking chips invented for prescription bottles

Medical Ethics - Research ethics and placebo use debated

Medical Malpractice - Chiropractor sentenced to 18 months in prison for patient death

Medical Malpractice - Debate over limiting jury awards comes to Pennsylvania Senate

Medical Malpractice - Doctor suspended after allegedly showing up for surgery drunk

Medical Malpractice - Insurer to leave Wyoming

Medical Malpractice - Pennsylvania Senate approves bill to cap liability awards

Medical Malpractice - Pennsylvania doctor convicted in drugs-for-sex trial

Medical Malpractice - Prosecutors say dentist performed unnecessary surgery

Medicare - Florida doctor convicted of fraud

Medicare - Health insurance plans moving forward on drug discount card for beneficiaries

Medication - Doctors say take medication with milk when food is unavailable

Medulloblastoma - ERBB2 protein might identify medulloblastoma patients resistant to treatment

Menopausal Symptoms - Research validates efficacy of herbal remedy MenoCare

Menopause - Many variables affect hair thickness and its other properties in aging women

Menopause - Ovarian failure changes reproductive mechanisms, not energy balance

Menstruation - Prostacyclin plays a pivotal role in normal and dysfunctional menstruation

Mental Health - Child soldiers are the subject of study on hidden trauma

Mental Health - Judge approves murderer's release from Wisconsin mental health facility

Mental Health - Maine's court master says courts should no longer manage psychiatric facilities

Mental Health - Mental healthcare accreditation debated in Louisiana

Mental Health - Missouri Governor signs bill to improve mental health care for kids

Mental Health - Oregon settlement sends 69 patients home from mental hospital

Mergers & Acquisitions - Amedisys finalizes deal to purchase home care agencies from Tenet

Mergers & Acquisitions - Analytical technology company completes acquisition of NuGenesis Technologies

Mergers & Acquisitions - Anthem-WellPoint merger wouldn't hurt consumers, regulators say

Mergers & Acquisitions - Assets of Hematronix purchased by diagnostics services company

Mergers & Acquisitions - Assets of biotech firm involved in immune regulation, hepatitis acquired

Mergers & Acquisitions - Attentus Healthcare reiterates interest in acquisition of SunLink

Mergers & Acquisitions - Biotech company initiates mergers and acquisitions plan for cord blood bank

Mergers & Acquisitions - Cancer therapy systems manufacturer to acquire medical software supplier assets

Mergers & Acquisitions - Equity interest taken in Detekt Biomedical

Mergers & Acquisitions - Fisher completes acquisition, expands its portfolio of proprietary products

Mergers & Acquisitions - Holding company acquires Skyline Orthopedics, Inc.

Mergers & Acquisitions - Invacare acquires California seating-products maker

Mergers & Acquisitions - LabOne completes acquisition of Northwest Toxicology

Mergers & Acquisitions - Molina Healthcare to acquire Health Care Horizons in New Mexico

Mergers & Acquisitions - MultiPlan closes acquisition of BCE Emergis U.S. provider network operations

Mergers & Acquisitions - National Health Services, Inc., acquisition completed

Mergers & Acquisitions - Neutron Enterprises, Inc., completes merger; retains legal, accounting firms

Mergers & Acquisitions - Pure Encapsulations acquired for $50 million in cash

Mergers & Acquisitions - RehabCare Group, Inc., announces acquisitions

Mergers & Acquisitions - Respiratory products developer announces acquisition

Mergers & Acquisitions - SHPS Holdings, Inc., and Landacorp, Inc., sign merger agreement

Metastatic Breast Cancer - CNS metastases from breast cancer can occur after trastuzumab treatment

Migraine - Off-label use of drug gives children relief

Military Health - Report says U.S. Defense Department failed to bill private insurers for millions

Mitral Regurgitation - Clip device accomplishes endovascular, nonsurgical repair of faulty heart valve

Molecular Biology - Microchambers and interconnecting plumbing automate the gene isolation

Multiple Endocrine Neoplasia - Parathyroidectomy is needed to prevent recurrent hyperparathyroidism in MEN 1

Multiple Sclerosis - Stress of losing a child increases risk of MS

Myelodysplastic Syndrome - Protein 4.1 deficiency linked to acquired elliptocytosis

Myelodysplastic Syndrome - Revlimid receives orphan drug designation by the European Commission

Myocardial Infarction - Beta blockers usage low despite insurance

Myocardial Infarction - Community hospitals do not transfer high-risk heart patients for aggressive therapy

Myocardial Infarction - Emory researchers find race and gender gaps in treatment of heart attack

Myocardial Infarction - Following care guidelines reduces risk of death within 1 year of heart attack

Attention Deficit Disorder - Better driving by teens with ADHD may be due Concerta

Atrial Fibrillation - Studies reinforce potential benefits of new stroke-prevention drug

Atherosclerosis - Progenitor cells predict heart disease severity

Asthma - Inhaled steroid therapy does not reduce fetal growth

Atherosclerosis - Endothelial catalase overexpression attenuates oxidant-mediated injury

Assisted Reproduction - Study to explore use of PGD in lowering multiple birth rates

Artificial Blood - Progress in development of blood substitutes reported

Arterial Blockage - AccuMist Stent Coating System sales announced

Arrhythmias - New technique tracks irregular heartbeats

Arrhythmias - World Trade Center attack linked to rise in irregular heartbeats in Florida patients

Arrhythmias - Implanted defibrillators not covered for patients who could benefit

Antibiotics - Partnership to develop novel formulation of amoxicillin

Antibacterials - FDA approves Cecure anti-bacterial spray for poultry

Antibiotics - Major determinants of activity of antibiotic peptide described

Anthrax Vaccine - Phase I clinical trial results of anthrax vaccine candidate reported

Anthrax Vaccine - FDA-licensed anthrax vaccine supplied to Taiwan

Angiotensin - Angiotensin II attenuates caspase-3 activation in cortical neurons

Angioplasty - Drug-coated stents aid heart procedure

Angiology - Polymorphism in gene promoter linked to increased bilirubin and HDL levels

Anemia - Detecting vitamin B12 deficiency prevents anemia and memory loss

Angiology - Matrix metalloproteinase-9 is needed for revascularization after ischemic injury

Amyotrophic Lateral Sclerosis - Studies support role of glutamate, RNA processing in muscle-wasting disease

Alzheimer Disease - Vaccine shows promise in animal model

Alzheimer Disease - Physiological role of beta-amyloid peptide explains Alzheimer disease

Alzheimer Disease - New study shows need for quick Alzheimer test

Alzheimer Disease - Common bacteria linked to brain disease

Alzheimer Disease - ACE gene polymorphism linked to damage in Alzheimer disease

Alzheimer Disease - A-beta antibody levels not changed in patients with Alzheimer disease

Allergy Medicine - Phase II/III trial initiated for ragweed allergy immunotherapy

Allergy Medicine - Increased thrombin activity occurs after allergen challenge

Alcoholism - Babies born to alcoholic mothers may suffer permanent nerve damage

Alcoholism - Alcoholism and obesity may involve overlapping neuropeptide pathways

Adolescent Health - Teens taking home pregnancy tests may be hoping for baby

Age-Related Macular Degeneration - Macugen data presented at Aspen Retinal Detachment Society meeting

Adolescent Health - Study links teens' "sense of self" to alcohol, drug use, and sex

Adolescent Health - Six states plan anti-huffing program for teens that get high on inhalants

Adipose Tissue - Preadipose cell changes into smooth muscle-like cells investigated

Addiction Medicine - Women, drinkers, and older people are at risk for prescription drug misuse

Adipose Tissue - Beta-adrenergic receptor agonists increase apoptosis of adipose tissue

Addiction Medicine - Study: Alcohol treatment meds, behavioral therapy effective for cocaine addiction

Addiction Medicine - GABAB receptor agonists exert bidirectional effects on dopamine

Acute Coronary Syndrome - Analysis from TACTICS-TIMI 18 trial published

Actinic Keratosis - FDA approval granted for immune response modifier for precancerous skin lesions

Abortion - Ultrasounds are advised for all women who request pregnancy termination

Abortion - Florida senate panel okays parental notice measure for minors seeking abortions

Abortion - Judge orders University of Michigan to turn over abortion records

Nutrition - Will an apple a day keep the doctor away?

Geriatrics - Tai chi training may help reduce falls in the elderly

Cognitive Function - Evidence suggests that the brain can switch to "automatic pilot" during learning

Angina - Daily aerobic activity treats chest pain, at half the cost of stenting

Sleep Apnea - "White coat hypertension" common among sleep apnea patients

Post-traumatic Stress Disorder - Losing consciousness can stop you from getting PTSD

Pediatric Obesity - Metabolic "footprint" may be new measure of heart risk in obese kids

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