Health and Medicine Week

Autism - Scientists identify gene variant

Developmental Biology - Missing gene a potential risk factor for birth defects

Complementary & Alternative Medicine - Pilot program will develop CAM curricula for medical institutions

Environmental Toxins - Why passive smoking hinders healing

Injury Prevention - Motor vehicle crashes claim more than a million lives worldwide

Skin Infections - Australian "mud football" game sickens players

AIDS - NIH grant to be used to develop novel anti-HIV therapeutics

Abortion - More maternal deaths could be avoided if procedure was performed earlier

Abortion Ban - Court battle over federal abortion law begins in three cities

Abortion Ban - Federal abortion ban challenged in Lincoln, Nebraska

Abortion Trend - Kansas residents having fewer abortions in state

Abuse - Middle-aged women just as likely to suffer abuse as younger women

Accreditation - Central DuPage Hospital becomes second accredited chest pain center in Illinois

Accreditation - Cigna Behavioral Health earns URAC accreditation

Acne - Positive results reported from Velac phase III pivotal trials

Acute Coronary Syndrome - Improved treatments needed to prevent restenting in diabetic patients

Addiction Medicine - Adolescents at risk for drug abuse need to acquire self-control competencies

Adiposity - ASP/complement C3adesArg deficiency increases energy expenditure

Adolescent Health - Emergency contraceptive availability doesn't boost rate of teen unprotected sex

Adolescent Health - Progress to sex in new teen relationships seems determined by gender

Adverse Drug Effects - Alfacalcidol treats glucocorticoid-induced osteoporosis

Adverse Drug Effects - Flutamide produces liver toxicity and a death in Germany

Adverse Drug Effects - Tamoxifen might stimulate the growth of PCDGF/GP88-positive breast cancer

Aesthetic Medicine - Dallas plastic surgeon among the first in the U.S. to offer Restylane

Aging - Calorie restriction extends lifespan, reduces cancer

Aging - Majority of surveyed women over 35 unafraid of aging

Alcoholism - Time for coordinated action on alcohol, says U.K. group

Allergies - Advances in treatment, diagnosis of food allergy, colic presented

Allergy & Immunology - Lymphocyte transformation test useful to determine occupational hazards

Allergy Medicine - Allergy season can mean asthma trouble

Allergy Medicine - Impact of asthma major focus for AAAAI in 2004

Allergy Medicine - Kinetics of eosinophilopoiesis after allergen inhalation reported

Allergy Medicine - Lactic acid bacteria and allergen induce immune response in allergy model

Allergy Medicine - Study: Food allergies now believed to affect 1 in 25 Americans

Alliances - Pharma-biotech alliances prove to be good investments, states report

Alzheimer Disease - Brain amyloid imaging in Alzheimer disease with Pittsburgh Compound-B

Analgesia - Analgesic therapy may offer protection against bladder cancer

Anaphylaxis - Positive data presented for inhaled form of epinephrine

Anemia - Anemia among cancer patients can be treated with human erythropoietin

Angina - Status of percutaneous myocardial revascularization submission reported

Angiology - Contrast agent concentration in mouse blood used to determine tumor vascularity

Angiology - Early ligation of inferior pancreaticoduodenal artery reduces blood loss

Angiology - Sinusoidal capillarization is distinct from angiogenesis in benign liver tumors

Angioplasty - Restenosis inhibited by tissue factor pathway inhibitor

Ankylosing Spondylitis - Lipid peroxidation increased in patients with ankylosing spondylitis

Anthrax Vaccine - Guardsman who refused anthrax vaccine discharged from Army

Anthrax Vaccine - Needle-free skin patch vaccination method for anthrax developed

Anti-Infectives - Chlorhexidine comparable to hexachlorophane for neonatal S. aureus control

Anti-Infectives - Low rate of enterococcal/staphylococcal resistance against oxazolidinone AZD2563

Anti-smoking Measure - Detroit leader vetoes anti-smoking measure

Antioxidant - Ascorbic acid inhibits oxidative modification of apolipoprotein E

Assisted Reproduction - FDA approves Follistim AQ Cartridge

Assisted Reproduction - Pregnancy via IVF more likely in months with longer daylight hours

Asthma - Asthma influenced by race and genetic make-up, studies show

Asthma - Clinical data reported on Alvesco and on its intranasal formulation

Asthma - Data supports benefits of second-generation immunomodulatory oligonucleotides

Asthma - pH of exhaled breath condensate can predict asthma exacerbations in children

Asthma Epidemiology - Nine million U.S. children diagnosed with asthma, new report finds

Atherosclerosis - Lipoproteins inhibit cholesterol efflux to apolipoprotein A1

Atherosclerosis - Study: Eating walnuts improves endothelial function

Autism - Theory on brains sparks debate

Autism Risk Factor - Issues surrounding the MMR vaccine and autism discussed

Avian Influenza - Flu expert says ban hogs and chickens on same farm

Avian Influenza - Vaccination of infected flocks could backfire without proper surveillance

Bacillus Calmette-Guerin - Immunogenicity of recombinant BCG vaccine strains investigated

Bacterial Endotoxin - FDA approval granted to manufacture Pyrotell products at new facility

Bacteriology - Differences found between genomes of oral pathogens and related spirochetes

Bariatrics - Web-based resource launched for management of bariatric patients

Benign Prostatic Hyperplasia - Alfuzosin 10 mg shows beneficial effect in patients with urinary retention

Biological Therapy - Altered Rho GTPase signaling pathways potential target for breast cancer therapy

Biological Therapy - Silenced clusterin-apolipoprotein J gene causes cancer cells to implode

Biological Warfare - Funding secured for hand-held biothreat detection device

Biomaterials - Phosphobetaine-based copolymer coatings superior to sulfobetaine coatings

Biotechnology - "Infectivity PCR" enhances detection of replication-competent adenovirus vectors

Biotechnology - Novel protein A/nano-gold immobilization system improves antibody analysis

Bladder Cancer - Form of vitamin E appears beneficial in reducing cancer risk

Bladder Cancer - Intra-arterial chemotherapy relieves symptoms of advanced bladder cancer

Bladder Cancer - New phase II/III Bexidem trial launched

Bladder Cancer - Vitamin E linked to lower risk of bladder cancer, according to study

Blood Bank Management - Company announces updated version of Surround for blood centers

Bone Marrow Transplantation - Biotechnology company announces breakthrough in cord blood stem cell expansion

Bone Void Filler - FDA issues clearance for new bone void filler

Bovine Spongiform Encephalopathy - U.S. Agriculture Department investigators criticize mad cow lab security

Bovine Spongiform Encephalopathy - Washington Governor vetoes mad cow measure

Brain Cancer - Erthropoietin improves learning and memory impairment after brain irradiation

Brain Cancer - Invisible light and special goggles may improve brain tumor surgery

Brain Monitoring - DARPA funding awarded for advancement of brain monitoring device

Brain Tumors - Brain tumor patients may present with headache

Brain Tumors - EGF gene may be therapy target and prognostic marker for glioblastoma

Breast Cancer - Androgen receptor polymorphism alters breast cancer risk in hormone therapy

Breast Cancer - Angiogenesis gene linked to biomarkers of tumor-cell growth

Breast Cancer - Breast pain as the only presenting symptom is rarely associated with cancer

Breast Cancer - Circulating tumor cells in breast cancer reviewed

Breast Cancer - Cystic hypersecretory breast lesions encompass a spectrum of pathologic lesions

Breast Cancer - Data shows mammography rates are stagnant in Florida

Breast Cancer - Elliptical MammoSite balloon catheters receive FDA marketing clearance

Breast Cancer - Emmprin enhances several malignant properties of cancer cells

Breast Cancer - FDA clears to market breast cancer assessment applications

Breast Cancer - Fulcrum mammography film digitizer and technology issued two U.S. patents

Breast Cancer - Higher levels of certain proteins may have diagnostic use for breast cancer

Breast Cancer - Many women covered by Medicare are not having mammograms

Breast Cancer - Minimally invasive breast cancer treatment shows promise

Breast Cancer - New contrast agent aids MRI detection of lymph-node metastases

Breast Cancer - New findings published on treatment for late-stage breast cancer

Breast Cancer - New sponsor announced for 2004 Komen Race for the Cure Series

Breast Cancer - New tumor marker discovered

Breast Cancer - Prune cAMP phosphodiesterase binds nm23-H1 and promotes breast cancer metastasis

Breast Cancer - Regulatory approval sought for use of Taxotere in early stage breast cancer

Breast Cancer - Rho GTPases represent signaling convergence points and relay switches

Breast Cancer - Sentinel node biopsy may avoid complete lymph node dissection in breast cancer

Breast Cancer - Study says breast cancer survival improves if women stay active

Breast Cancer - Survey reports fall in stem cell transplants for breast cancer

Breast Cancer Prognosis - Poor responsiveness of breast cancer to chemotherapy explained by profile

Breast Cancer Prognosis - p53 expression does not play role in recurrent breast cancer

Breast Cancer Therapy - Bispecific antibody MDX-H210 with filgrastim highly effective in early trials

Breast Cancer Therapy - Exemestane and aromatase inhibitors play role in breast cancer management

Breast Implants - Company receives European approval for new silicone gel breast implant

Breast Implants - Timeline set for breast implants settlement deal

Bronchitis - Paroxetine effective as antitussive in opioid-resistant cough

Business & Finance - 89% of surveyed companies consider outsourcing a strategic tool

Business & Finance - Alliance Retail Management Group to represent O24 product line in Canada

Business & Finance - Biotechnology company receives $3M through private offering

Business & Finance - Company files 510(k) for its Atrilaze Soft Tissue Ablation System

Business & Finance - Drug discovery collaboration to develop novel small molecule therapeutics

Business & Finance - Medical device company announces sale of rotational thrombectomy technology

Business & Finance - Pharmaceutical company announces discontinuation of operations

Business & Finance - Pharmaceutical company comments on potential spin-off

Business & Finance - Report announces leader in neurology drug market

Business & Finance - Research collaboration extended

Business & Finance - Specialty pharmaceutical company acquires Fosrenol patent rights

Business & Finance - Squalamine maker reports 2003 net loss of $12.5 million

Business & Finance - Supply and license agreements signed for NeoVisc and Uracyst in U.S. markets

Business & Finance - Therapeutics company announces reincorporation to Delaware

Business & Finance - Three U.S. health plans to implement InformedRx pharmacy benefits services

Business & Finance - Xopenex co-promotion agreement announced

Business Update - ANDA filings pending for Concerta; Wellbutrin marketing rights relinquished

Business Update - Company announces first results of antiwrinkle study; gets private financing

Business Update - Consultants less critical but still not recommending Washington insurer's plan

Business Update - Eastern Washington hospitals threaten to cancer contract with insurer

Business Update - Embrex opens biotech plant in Scotland County

Business Update - Genomics company "sharpens" focus, announces layoffs; CEO to retire

Business Update - Humana finalizes purchase of Louisiana managed-care business

Business Update - Hydroxyapatite coating technology passes key systemic injection test

Business Update - Insurance company president's benefits included loan forgiveness

Business Update - Nurses, Cooper Hospital reach tentative contract

Business Update - Preferred provider organization launches fee negotiation program

Business Update - Proteomics company announces mission statement

Cancer - European patent grants claims covering vascular targeting agent technology

Cancer - Proteins exploit disorderliness to perform a variety of different jobs

Cancer Fraud - Woman says she faked daughter's cancer to keep husband from leaving

Cancer Metastasis - Ezrin may promote tumor metastasis

Cancer Prevention - West Virginia University cancer program gets top rating

Cancer Risk - Studies fail to find link between cancer and a common fried food chemical

Cancer Risk Factor - Human papillomavirus infects all ages of women in Nigeria

Cancer Therapy - Chemotherapy of anaplastic oligodendroglial tumors outlined

Cancer Therapy - Company reports additional positive data from MBT-0206 phase I trials

Cancer Therapy - Conjugates containing HPMA copolymer and TNP-470 target tumor angiogenesis

Cancer Therapy - Expanded roles for checkpoint kinases suggest target modification

Cancer Therapy - Multimodality therapy for rectal cancer led to massive iliac artery bleeding

Cancer Therapy - New radiation treatment system installed at UC Davis Cancer Center

Cancer Therapy - Oocytes from children and young adults undergoing radiation can be preserved

Cancer Therapy - Thrombospondin-1 predicts how tumors respond to low-dose cyclophosphamide

Cancer Vaccine - Exosomes act as potent cell-free peptide-based vaccines

Cancer Vaccine - High efficiency of low-affinity epitopes in cancer therapy reported

Cancer Vaccine - Natural killer T-like cells induced by thymoma expressing alpha-fetoprotein

Cancer Vaccine - Peptide-based vaccines for cancer immunotherapy reviewed

Carcinogenesis - Prenatal exposure to combustion-related pollutants damages DNA

Carcinogenesis - Tobacco toxins present in pregnant smokers' amniotic fluid in first trimester

Carcinoma - Adverse prognosis for renal cell carcinoma resection with esophageal metastases

Cardiology - Protein kinase C-alpha is a nodal integrator of cardiac contractility

Cardiology - Simvastatin employs VEGF in the regeneration of arterial endothelial cells

Cardiology - Ultrasound-guided ablation eliminates an acardiac twin

Cataracts - Calpain inhibitors show promise as targets of cataract prevention

Cell Signaling - Researchers solve 30-year puzzle of nerve cell function

Cerebral Malaria - Western neuropsychological tests can be modified to fit Kenyan children

Cerebral Palsy - Fetal heart monitoring ineffective at diagnosing brain injury

Cerebrovascular Diseases - Endovascular treatment is feasible for some cerebrovascular diseases and tumors

Cervical Cancer - Researchers involve underserved women in a cervical cancer prevention trial

Cervical Cancer - User-friendly recruitment strategy increased prevention study participation

Chemoresistance - Genomic alterations make cells more or less resistant to drug therapy

Childhood Obesity - Food stamp program linked to overweight in young children

Childhood Obesity - Soft tissue facial morphology different in obese adolescents

Cholestatic Hepatitis - Liver graft failure occurs despite antiviral prophylaxis

Chronic Hepatitis B - Interferon therapy restrains wild-type and precore mutated HBV equally

Chronic Lymphocytic Leukemia - Geldanamycin and herbimycin A make leukemia cells sensitive to chemotherapy

Chronic Myelogenous Leukemia Therapy - Cytogenetic CE alone does not reduce post-SCT imatinib efficacy

Chronic Obstructive Pulmonary Disease - Spiriva predicted to corner the COPD drug market

Clinical Trial - Company awarded $1.2M for cardiac safety monitoring and services

Clinical Trial - Positive results announced for pharmacokinetic trials with oral cladribine

Cognition - Cognitive dysfunction and subjective complaints of cancer patients studied

Cognition - Three variants of primary progressive aphasia described

Collaborations - Agreements signed for acquisition of rights to Loestrin oral contraceptives

Collaborations - Contract signed with pharmaceutical customer for assay development

Collaborations - Deal signed to develop bird influenza research program

Collaborations - Disease management firm announces StatusOne agreement

Collaborations - Distribution agreement signed for imaging products

Collaborations - Drug discovery technology licensed from Texas Tech University

Collaborations - Generex Biotechnology announces letter of intent for joint venture

Collaborations - Morton Grove signs exclusive agreement with company in India

Collaborations - NeoGenesis Pharmaceuticals announces drug-discovery collaboration

Collaborations - NursesSTAT adds services to maximize new business opportunities

Collaborations - Sublicense granted to Roche Diagnostics for cardiac marker

Colon Cancer - Beta-catenin may indirectly impact colorectal tumor progression or dormancy

Colon Cancer - Bilateral adrenal metastasis from colorectal cancer should be managed surgically

Colon Cancer - CPMP recommends approval of Erbitux

Colon Cancer - Existing therapies applied to new use in broader spectrum of cancer care

Colon Cancer - Researchers discover novel gene profile that may identify colon stem cells

Colon Cancer - Study reveals 52 differences in protein expression using DIGE technology

Colon Cancer - Urokinase plasminogen activator is increased during colon tumor transformation

Colonoscopy - Company begins phase II study of INKP-102, a purgative product

Colorectal Cancer - A new gene for familial cancer is found

Colorectal Cancer - FDA issues approval for colorectal cancer diagnosis and treatment system

Complementary & Alternative Medicine -  Ginkgo biloba extract stimulates endothelial progenitor cells

Complementary & Alternative Medicine - Efforts to standardize herbal supplement stymied by lack of research

Complementary & Alternative Medicine - Many Taiwanese homebound cancer patients use complementary therapy

Complementary & Alternative Medicine - Oriental medicine may inhibit mast cell activity in arthritis patients

Complementary & Alternative Medicine - U.S. government issues public briefing on safety of dietary supplements

Congestive Heart Failure - First MicroMed/DeBakey child ventricular assist device implanted

Contraception - Birth-control sponge near U.S. return

Coronary Artery Bypass - Desmopressin does not reduce postoperative bleeding in patients taking aspirin

Coronary Artery Bypass - Devices that facilitate anastomoses may revolutionize coronary artery bypass

Coronary Artery Disease - New growth factor protein helps damaged hearts

Coronary Artery Disease - Phase II trials initiated for pharmacologic stress agent for heart studies

Coronary Stents - Company sells $42M in stent systems in 10 days

Criminology - Rise in stranger homicides not linked to mental illness

Critical Care Medicine - End-of-life ICU use may require re-evaluation, study suggests

Crohn Disease -  M. paratuberculosis infection common in patients

Crohn Disease - Insurer updates reimbursement policy for capsule endoscopy

Cryptosporidium - Genetic diversity of Cryptosporidium species in reptile pets reported

Cystic Fibrosis - Diagnostics firm receives product of the year award

DNA Research - SCF component Skp2 degraded by anaphase-promoting complex

DNA Vaccine - Bacteria-mediated DNA transfer in gene therapy and vaccination reviewed

DNA Vaccine - Methylated CpG-containing plasmid activates immune system

Daytime Sleepiness - Enrollment complete for excessive daytime sleepiness trial

Decontamination Technology - Fumigation technology inactivates chemical, biological agents in research

Dendritic Cell Vaccine - Activation of dendritic cells translates innate into adaptive immunity

Dental Care - South Carolina rules may keep students from getting dental care in schools

Depression - Asian suicide rate higher in women

Depression - Employees with depression view illness as roadblock to career success

Depression - Generic bupropion hydrochloride sustained-release 150 mg launched

Depression - Home-based program effective in treating minor depression in older adults

Dermatology - Anti-p200 pemphigoid autoantigen characterized

Dermatology - CD4+ and HLA-DR+ T cells reduced in vitiligo patients

Developmental Biology - Researchers conduct first comprehensive proteomic analysis of developing animal

Diabetes - Navajo Health officials hope conference will make impact on diabetes

Diabetes - U.S. Health secretary holds town hall meeting on diabetes

Diabetes Epidemiology - Diabetes prevalence among Puerto Ricans affected by age, education

Diabetes Genetics & Genomics - PC-1 Q121 allele associated with type 2 diabetes

Diabetes Genetics & Genomics - Similarity in genomics of types 1 and 2 diabetes reported

Diabetes Link - Danish study finds no link between childhood vaccinations and diabetes

Diabetes Mortality - High death risk found among young people in hospital with diabetes

Diabetes Pathogenesis - Protein tyrosine phosphatase alpha not involved in insulin signaling

Diabetes Therapy - National trial to study best treatment of type 2 diabetes in youth

Diabetes Therapy - Peptide allows successful allogeneic islet transplantation in mice

Diabetes Therapy - Researchers one step closer to creating oral insulin

Diabetes Therapy - Success of new drug that may halt progression of type 1 diabetes

Diabetes Therapy - Treatment for insulin resistance in diabetes accompanying obesity is patented

Diabetic Nephropathy - GFPT1 variations not linked to diabetic nephropathy

Diabetic Neuropathy - Axon reflexes are diminished in diabetic small-fiber neuropathies

Diabetic Neuropathy - Neuropathy in type II diabetes mellitus by multimodal evoked potentials

Diabetic Neuropathy - Poly(ADP-ribose) polymerase inhibitors may treat diabetic neuropathy

Diabetic Retinopathy - Hyperglycemia thwarts angiogenesis without diminishing VEGF activity

Diabetic Retinopathy - Lilly to support screening for diabetic retinopathy

Diabetic Retinopathy - VEGF -460C polymorphisms predict diabetic eye disease

Diagnostic Imaging - High-field MRI provides a wealth of information when contrast is used

Diagnostic Imaging - Synchronous lymphoma and renal cell carcinoma may not be so rare

Diagnostic Imaging - Triple fusion reporter vectors identify gene expression in living subjects

Diagnostics - Highly specific probes detect hepatitis C virus in liver tissues

Diagnostics - IDI-MRSA receives FDA approval

Diagnostics - Methods for HAV detection in shellfish compared

Diagnostics - Normative data provide a baseline for screening first trimester Korean fetuses

Diagnostics - Prior biopsy scheme impacts pathologic features of cancers on repeat biopsies

Diagnostics - Rapid Medical acquires TB-related patents

Diagnostics - The relationship between diet and cancer is evaluated in 10 European countries

Diet & Nutrition - Dietary energy restriction may prevent skin carcinogenesis

Diet & Nutrition - Meat supplements make a favorable impact on the bone health of older people

Diet & Nutrition - Postprandial suppression of ghrelin does not predict intermeal interval

Disciplinary Action - South Dakota Board releases list of disciplined doctors

Disease Outbreak - Officials still mystified by cause of Pennsylvania school sickness

Disease Prevention - Bill requires Iowa students to get information on meningitis

Disease Transmission - Program teaches health workers about preventing mother-to-child HIV infection

Drug Ban - Oklahoma to be first to ban over-the-counter pseudoephedrine

Drug Delivery - B12 influences NF-kB survival signaling and antitumor activity of Apo2L/TRAIL

Drug Delivery - Consulting firm reports that transdermal drug delivery continues to grow

Drug Delivery - Patent issued for protein delivery

Drug Delivery - Researchers creating polymers that act like biomolecules

Drug Development - Anti-HIV activity of linear peptide gp120 inhibitors characterized

Drug Development - Company announces sale of Congers, New York, assets

Drug Development - Company reports advances in targeting Hypoxia-Inducible Factor

Drug Development - Definitive Phase 1 QT ECG trial required for drug safety assessment

Drug Development - Drug development provider inks multiyear contract with pharmaceutical company

Drug Development - Fatty acid pathway, glucose combine to produce triacetic acid lactone

Drug Development - Human anti-neuroblastoma antibody cloned

Drug Development - Lipophilic substitutions improve benzylpyrazole CCR5 antagonists

Drug Development - Novel C-10 non-acetal trioxane dimers show antimalarial, anticancer activity

Drug Development - Pharmaceutical firm awarded SBIR grant for antibody development

Drug Development - Targeting inactive RNA conformation effective drug design strategy

Drug Development - Technology company awarded fourth electronic data capture study

Drug Development - Timing of R&D/marketing efforts effect drugs' market performance, report shows

Drug Development - Transgenomic to provide manufacturing support for novel drug

Drug Discount Cards - CMS selects Medco for Medicare discount drug card program

Drug Discount Cards - Elderplan expands prescription drug benefits for members

Drug Discovery - Collaboration to develop and co-market focused libraries for kinase targets

Drug Discovery - Holding corporation reports 25% increase in 2003 revenues

Drug Discovery - Research collaboration to study matrix metalloprotease inhibitors

Drug Resistance - Cancer-altered apoptosis leads to tumor progression and therapy resistance

Drug Resistance - Interleukin-6 stimulates a protein known to cause chemoresistance

Drug Resistance - MUC1 transforming protein confers resistance to genotoxic anticancer agents

Eating Disorder - Simplistic explanations regarding women and body image neglect other factors

Eating Disorders - Body image "education" should start in middle school

Electronic Health Records - Initiative to provide affordable, standards-based EHRs enters next phase

Electronic Medical Records - Kryptiq joins AAFP Partners for Patients in EHR movement

Electronic Medical Records - Software developer to provide EMR technology for medical practices

Electronic Patient Records - Memorial Hermann implements Quovadx technology

Emergency Medicine - California emergency departments have maintained patient access, capacity

Emergency Preparedness - Biothreat detection device funding secured by public-private collaboration

Employer-Sponsored Health Insurance - Cap on premiums for small business insurance criticized

Employer-Sponsored Health Insurance - North Carolina paper mill will open in-house clinic to control health costs

Employer-Sponsored Health Insurance - Senator says small businesses should be able to pool insurance

Employer-Sponsored Health Insurance - Small businesses launch initiative for bare-bones health plan

Endocrinology - Cholecystokinin stimulates aldosterone from adrenocortical cells

Endocrinology - Function of mitogen-activated protein kinases in ovarian cells reported

Endocrinology - Genetic mutations associate with spontaneous ovarian hyperstimulation syndrome

Endocrinology - Growth hormone has reduced ability to activate kinase pathway

Endocrinology - Hormonal regulation of atypical absence seizures investigated

Endocrinology - Japanese licensee obtains approval for drug delivery technology in Japan

Endocrinology - PPAR-delta regulates intestinal adenoma growth in mice

Endocrinology - Parathyroidectomy improves depression in patients with hyperparathyroidism

Endocrinology - Role of CREB in CCAAT/enhancer-binding protein beta gene described

Endometrial Cancer - Active lifestyle reduces risk of most common gynecologic malignancy

Endometriosis - Peritoneal fluid macrophages jumpstart endometrial inflammation

Environment & Health - Better understanding of sex differences in environmental exposure needed

Environmental Health - Prenatal organochlorine exposure linked to low cord blood TNF-alpha levels

Environmental Toxins - Early exposure to environmental agents predicts adult tumors in animals

Environmental Toxins - Secondhand smoke levels dip in households with kids

Enzymology - Aminopeptidase A is a functional vascular target

Enzymology - Matrix metalloproteinase-8 plays a key role in cancer metastasis

Epidemiology - Study: Asian suicide rate higher in women

Epilepsy - Mutation in synapsin I reported in family with epilepsy

Erectile Dysfunction - Levitra refill rates three times higher than most recent entry in ED market

Erectile Dysfunction - Study: LEVITRA improved erectile function, reduced depressive symptoms

Esophagoscopy - Diagnostic Trans-Nasal Esophagoscope with Slide-On EndoSheath System CE Marked

Ethics - Dementia's moral maze explored

Euthanasia Trial - Euthanasia campaigner found guilty on charge of attempted murder

Evolutionary Biology - A bird "language" gene pinpointed

Evolutionary Biology - Bioinformatics experts help reconstruct the genomic makeup of our ancestors

Ewing Sarcoma - Long-term follow-up necessary for non-metastatic Ewing sarcoma

Family Medicine - Study produces recommendations to transform and renew family medicine

Femur Fractures - Subtrochanteric femoral nonunions heal with appropriate grafting and implants

Finance - Automated instrument reagent company fails to meet guidance

Finance - Biologics company raises financing for working capital

Finance - Biomaterials company receives $2.8 million through warrant exercise

Finance - Biopharmaceutical company announces 2003 financial results

Finance - Biopharmaceutical company announces sale of common stock

Finance - Biopharmaceutical company reports 2003 financial results

Finance - Biotechnology company completes $5.5M equity private placement

Finance - Blood-products company reports improved 2003 income

Finance - Cardiac device maker reports a $1.1M expense adjustment

Finance - Cell-therapy company raises $10.7 million in series B financing

Finance - Company reports financial impact of U.K. judicial decision

Finance - Device company announces $21M private placement of common stock

Finance - Device company commences trading of common stock on OTCBB

Finance - Device maker announces 16% sales-revenue growth in 2003

Finance - Drug-delivery company announces public offering of common stock

Finance - Flavin Ventures announces start-up for life sciences company

Finance - Food-safety company reports 29% revenue increase

Finance - Fund manager names likely healthcare stock winners in wake of Medicare reform

Finance - Genomics services provider announces 10b5-1 stock trading plan

Finance - Gentiva Director Stuart Olsten adopts 10b5-1 trading plan

Finance - Glucose monitor maker reports income of $1.01 per share

Finance - HIV test developer reports loss of $0.04 per share

Finance - HMOs in Missouri gain record profits

Finance - Health-technology company reports increased profits

Finance - Hearing aid company reports record $70.5 million 2003 revenues - up 23%

Finance - Hepatitis drug developer announces initial public offering

Finance - Hepler appointed to board of directors at biotech firm

Finance - Highmark healthcare operations post loss in 2003; vision and dental post gains

Finance - I-trax announces actual and pro forma results for 2003

Finance - Imaging company completes common stock offering

Finance - KRX-101 maker reports decreased net loss for year

Finance - Maker of neurological/psychiatric drugs announces $250M financing

Finance - Medical device manufacturer completes extended share repurchase program

Finance - Medical product developer reports 2003 financial results

Finance - Medical supply distributor reports increase in net loss

Finance - Metropolitan Health Networks reports full year of profitability

Finance - Michigan managed-care plans' gains may temper premium increases in coming year

Finance - Neurological-device company raises $10 million in additional venture financing

Finance - Neuroscience pharmaceutical firm reports 4Q loss of $0.25 per share

Finance - Omega Healthcare announces closing on private offering

Finance - Oncology company raises $12.8M in private placement

Finance - Pharmaceutical company files statement for common stock offering

Finance - Pharmaceutical company renews revolving term credit facility

Finance - Pharmaceutical company reports loss of $0.68 per share

Finance - Pharmaceutical firm announces pricing of common stock offering

Finance - Pharmaceuticals company reports quarterly loss of $0.19 per share

Finance - Revenue guidance of $40-50M given for skin disorders drug Cubicin

Finance - Rule 10b5-1 stock trading plans announced

Finance - Safescript Pharmacies, Inc., files for Chapter 11 bankruptcy protection

Finance - Theranostics company completes $750,000 private financing

Finance - Thermotherapy developer expects record second quarter results

Finance - Uniphyd engages advisor to raise debt and equity financing

Finance - Valve maker reports revenue up 42% through third quarter fiscal year 2004

Finance - Wound-healing company notified that its shares will be delisted

Finance - X-ray technology company announces filing of S-3 registration statement

Fitness - Martial arts good alternative to the gym for boosting fitness in middle age

Fitness - Study finds no evidence that stretching prevents injuries

Fitness - Wrestling boosts immune system of adolescent boys

Fitness & Wellness - Children sleeping less than recommended

Fitness & Wellness - Manchester, New Hampshire, schools launch effort to help students slim down

Fitness & Wellness - Vermont Governor issues challenge to state's kids

Food-Borne Illness - Acid exposure improves enrichment of enterohemorrhagic E. coli

Forecast - Study: CerAxon will corner the neuroprotectant drug market in 2013

G Lymphatic Insufficiency - Stanford inks Fractal Genomics Modeling agreement

Gastric Cancer -  H. pylori CagA proteins may raise risk of gastric cancer in East Asians

Gastric Cancer - Second-line chemotherapy contributed to favorable outcome in gastric cancer

Gastroenteritis - Novel PCR assay enables norovirus genotyping

Gastroenterology - Inducible nitric oxide synthase sensitizes colorectal cancer to radiation

Gastroenterology - Results of 100-patient M2A capsule endoscopy outcome study published

Gene Analysis - Altered caveolin and thrombospondin reveal liver cancer vessel status

Gene Analysis - New RNA libraries can inactivate human genes selectively

Gene Expression - Single rat array launched for whole-genome expression analysis

Gene Expression - Study validates first universal microarray RNA expression system

Gene Therapy Vectors - Sheep retrovirus Env efficiently pseudotypes HIV-based lentiviral vectors

Gene Transfer - A new cleavage product gives real-time information about transgene activity

Gene Transfer - Vectors encoding for angiostatin and endostatin surpass single-encoded vectors

Generic Drugs - Company receives FDA approval and 180-day exclusivity for nitrofurantoin

Generic Drugs - Company receives tentative approval for Felodipine ER

Generic Drugs - FDA approves generic versions of Declomycin, Wellbutrin

Generic Drugs - FDA approves hydrocodone bitartrate and ibuprofen tablets 5/200 mg tablets

Genetic Disorder - Neuroretinal dysfunction found in heterozygote for CLN3 defect

Genetic Disorder - Prevalence of hypercholesterolemia mutation in Quebec reported

Genetic Disorders - Umbilical and placental veins of babies with HHT1 thrive despite low endoglin

Genetic Engineering - Genetically altered mice predict toxicity for individual targeted cancer therapy

Genetic Mapping - Lab rat's genetic code should yield insight into human evolution and disease

Genomic Biomarkers - Company contributes drug signatures to promote biomarker research

Genomics - Direct analysis of single molecules without amplification announced

Geriatrics - Caloric intake, body weight independently affect longevity

Geriatrics - Scientists develop new drug treatment for memory loss in old age

Gestational Diabetes - Glucose values improve throughout gestation in triplet pregnancies

Gifts - Retired doctor pledges $1 million to Southwestern College

Glanzmann Thrombasthenia - Factor VIIa restores aggregation of platelets

Gynecological Surgery - Patients should consent to medical student pelvic exams before anesthetization

Gynecology - Angiostatic agents look promising for treating endometriosis

Gynecology - Nomograms help identify abnormality of ovaries during sonographic examination

Gynecology - The ceruloplasmin promoter shows an affinity for ovarian tumors

HIPAA - Judge tosses out lawsuit challenging medical privacy rules

HIPAA Compliance - Employers offering health plan benefits subject to HIPAA deadline

HIV Prevention - FDA accepts IND for unique HIV vaccine

HIV/AIDS - At-Home hepatitis C, instant cholesterol, allergen, and HIV test announced

HIV/AIDS - Australian doctors lose appeal against woman who caught HIV from her husband

HIV/AIDS - Cambodian sex workers turn down Bill Gates-funded HIV drug

HIV/AIDS - Companies receive European positive opinion for Telzir

HIV/AIDS - Company ships 100,000 Rapid HIV test kits to China, first of 1.3 million order

HIV/AIDS - Efforts to get AIDS medications to developing countries may be near breakthrough

HIV/AIDS - FDA approves test to detect HIV-2 antibodies

HIV/AIDS - HIV/AIDS prevention efforts increase in Wyoming

HIV/AIDS - South Carolina gets $19 million for AIDS research and treatment

HIV/AIDS Diagnosis - Doubly indeterminate HIV Western blot results are negative

HIV/AIDS Drug Resistance - Fitness loss caused by HIV resistance mutations may account for low viremia

HIV/AIDS Drug Resistance - Prevalence of HIV resistance mutations in Brazil determined

HIV/AIDS Genomics and Genetics - "Somatic hypermutation" hypothesis for HIV R5-X4 switch proposed

HIV/AIDS Genomics and Genetics - Mutation rates of HIV genomes clarified

HIV/AIDS Immune Control - IL-15 levels elevated in patients with discordant response to treatment

HIV/AIDS Immune Control - Scavenger function of CCR5Delta32 protein involved in protection from HIV

HIV/AIDS Opportunistic Infection - Aeration augments Aspergillus fumigatus gliotoxin production in vitro

HIV/AIDS Opportunistic Infection - Antisera-based immunoassay effective for aspergillosis diagnosis

HIV/AIDS Pathogenesis - Ability of HIV LysRS to bind tRNA determines virion packaging efficiency

HIV/AIDS Pathogenesis - Expansion of tumor antigen-specific T cells in transgenic mice reported

HIV/AIDS Prevention - AIDS virus is vulnerable in initial stage of infection

HIV/AIDS Protein Research - Chimeric HIV/SIV provides stable trimeric HIV Env for study

HIV/AIDS Risk - Biology, not behavior, could explain reduced risk of HIV for circumcised men

HIV/AIDS Therapy - Enfuvirtide is new fusion inhibitor for HIV infection treatment

HIV/AIDS Therapy - MALDI-TOF MS assay provides improved NRTI monitoring

HIV/AIDS Vaccine - Assays with extended incubation phases needed to monitor HIV vaccine trials

HIV/AIDS Vaccine - HIV-1 infection blocked via CCR5 and CXCR4 receptors

HIV/AIDS Vertical Transmission - Girls may have heightened risk of intrauterine HIV infection

HIV/AIDS Vertical Transmission - Mortality from formula use and vertical HIV transmission comparable

HIV/HCV Coinfection - Undetectable HCV viremia and normal liver enzyme levels may not mark cure

Head and Neck Cancer - High rates of mitochondrial DNA instability mark squamous cell carcinoma

Head and Neck Cancer - RASSF1A hypermethylation is an early sign of thyroid cancer tumorigenesis

Headaches - Company receives purchase order from Eckerd for OTC migraine therapy

Health-Risk Behaviors - Death shows danger of silicone injections

Healthcare & Politics - Price tag of Kerry health plan drops in new analysis

Healthcare Coverage - Aetna introduces PPO plans for individuals, families in Pennsylvania, Delaware

Healthcare Coverage - Alabama Governor loses in Senate committee on health insurance issue

Healthcare Coverage - Auditor gives Vermont mixed review of insurance premium program

Healthcare Coverage - Benemax provides online second-opinion service

Healthcare Coverage - California Governor has no position on key health care initiative

Healthcare Coverage - HealthPartners to offer Medicare-endorsed drug discount card

Healthcare Coverage - Insurer tailors website to give members more control over healthcare benefits

Healthcare Coverage - Lottery winnings must be reported by TennCare enrollees

Healthcare Coverage - Maine becomes model as universal health plan takes shape

Healthcare Coverage - Maryland House votes to offer medical care to 280,000 uninsured

Healthcare Coverage - Medicare to cover wound-treatment system

Healthcare Coverage - Missouri legislators endorse bill expanding high-risk health insurance pool

Healthcare Coverage - Papers compare costs of universal coverage with social costs of uninsurance

Healthcare Coverage - PreferredOne offers TriZetto consumer-directed application

Healthcare Coverage - Program for chronically ill elderly patients cuts healthcare costs

Healthcare Coverage - UnitedHealth Group issues electronic benefits cards

Healthcare Coverage - Walgreens Health Initiatives to offer Medicare-approved drug discount card

Healthcare Coverage - WellCare to offer Medicare drug discount cards in Florida and New York

Healthcare Coverage - Wisconsin BadgerCare extension approved

Healthcare Economics - Co-pays for brands, generics up along with employee deductibles, contributions

Healthcare Economics - South Dakota legislator wants healthcare providers to publicly list prices

Healthcare Models - Family physicians in group model HMO feel powerless, undervalued

Healthcare Protection - Federal legislation introduced to protect health of ground zero crews

Healthcare Services - Revenue drying up for nonprofit agencies

Healthcare Training - Additional online training available for Triage Cardio ProfilER

Hearing Loss - Sprint launches CapTel Relay Service for hard of hearing community

Heart Attack - Blood-forming stem cells fail to repair heart muscle

Heart Attack - Cardiac device firm launches completely automatic AED

Heart Disease - Central Ohio hospital granted designation of Accredited Chest Pain Center

Heart Disease - Drug delivery firm completes trial for optimization of paclitaxel stent

Heart Disease - PPAR-gamma role in cardiovascular disease reviewed

Heart Disease Mortality - Combination of two common heart tests is strong predictor of death in patients

Heart Disease Risk - New tool predicts and manages cardiovascular disease risk

Heart Disease Risk - Repeated treatment of gum disease reduces levels of inflammatory factors

Heart Disease Risk - Study questions value of inflammation test

Heart Disease Risk Factor - Evolving targets for cardiovascular risk reduction in diabetes reviewed

Heart Disease Risk Factor - Signs of cerebral amyloid angiopathy-related inflammation reported

Heart Disease Therapy - Antarctic fish study may aid cardiac research

Heart Failure - Company reports preliminary results for EMOTE; doesn't reach primary endpoint

Heart Failure - Positive results reported in preclinical trial of Anginera

Heart Health - Research questions value of test to predict heart attacks

Heart Valve Prosthesis - Researchers develop a porcine model for a bileaflet heart valve prosthesis

Hematology - Automated Hematology Analyzer Body Fluids application cleared by FDA

Hematology - Central role of the P2Y₁₂ receptor in platelet activation

Hematology - Cynomolgus macaques model the effects of hemophilia B gene therapy

Hematology - Mediators of cytokine-induced stem-cell survival identified

Hematology - New therapies help patients beat cancer-related anemia

Hematology - Stem cells in the spleen rely on neoangiogenesis for relocalization

Hematology - Thalidomide helps endothelial cells escape doxorubicin-induced apoptosis

Hematology - Thrombin can predict response to tissue factor challenge

Hematology - Unrelated bone marrow transplants treat patients with non-Hodgkin lymphoma