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Reproductive Medicine

First pregnancy induced with vitrified zona-free blastocyst reported

Published in Health and Medicine Week, May 17th, 2004

For the first time, a vitrified zona-free human blastocyst has been successfully used to induce pregnancy.

In a recent case report, scientists in Japan described a "31-year-old woman" who, "after failed stimulated and thaw cycles, underwent short-treatment protocol stimulation," after which "oocytes were recovered transvaginally with ultrasound guidance.

"Eight mature oocytes were obtained and six were fertilized with conventional IVF," explained K. Hiraoka and coauthors at the Kinutani Women's Clinic in Hiroshima. "Consecutive embryo transfer was performed, in which two cleaved embryos were transferred on day 3 and a single blastocyst was...

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