Health and Medicine Week

Healthcare Access - Hospitals' affiliation brings pediatric specialists to central New Jersey

Healthcare Access - Medical Center serving patients in remote areas through telemedicine technology

Healthcare Access - Tenet California and Blue Shield of California sign new hospital agreement

Healthcare Costs - Senate candidate calls for changes in medical and legal systems

Healthcare Coverage - Advocates in North Carolina want healthcare as a constitutional right

Healthcare Coverage - Oregon Health & Science University to take fewer low-income patients

Healthcare Coverage - Report says 17,000 immigrant kids have lost healthcare in Kentucky

Healthcare Coverage - Retirees fear drug benefit cuts, pushing them into costlier Medicare plans

Healthcare Coverage - Study finds many Arkansans are cautious of doctors

Healthcare Fraud - Ex-lawmaker, former Braves pitcher indicted in fraud case

Healthcare Funding - Advocacy groups offer alternate welfare cut plan in West Virginia

Healthcare Funding - Canadian opposition scornful as Prime Minister promises billions for healthcare

Healthcare Funding - Louisiana's House approves $18 billion spending bill

Healthcare Products - Ultra violet rays monitor and toothbrush purifier available to consumers

Heart Attack - North Carolina hospital receives Chest Pain Center accreditation

Heart Attack - U.S. FDA issues clearance for RAMP Cardiac Marker Test

Heart Disease - Approval sought for human implantation of self-expanding stented heart valve

Heart Disorders - Collaboration to develop 3D image technology for electrophysiologists

Heart Failure - AbioCor implant patient removed from life support due to liver, kidney failure

Heart Failure - Implantable cardioverter defibrillator study results released

Heart Failure - Nitroglycerin does not affect cardiac autonomic control in heart failure

Heart Transplantation - LF15-0195 inhibits NF-kappaB signaling through IKK suppression

Helicobacter - Relation of Chinese H. pylori genotype to gastric disease examined

Helicobacter Pylori - IL-1 genotype may determine clinical outcome of H. pylori infection

Hematologic Disease - Use of bortezomib in hematologic malignancies updated

Hematological Cancer - Molecular WT1 assay useful for minimal residual disease monitoring

Hematology - Forced Notch4 expression holds myeloid cell differentiation at bay

Hematology - Incidence of anemia increases with age

Hematology - Insulin-like growth factor is a comprehensive cytokine in multiple myelomas

Hematology - Lung cells give rise to lymphohematopoietic cells in irradiated animals

Hematology - Platelet cyclic 3', 5'-guanosine monophosphate inversely correlates with age

Hematology - Vascularizing tumors actively recruit bone marrow stromal progenitor cells

Hemodialysis - Convective-controlled double high flux hemodiafiltration shows promise

Hemodialysis - Tailored schedules may help retain residual renal function

Hepatitis - New preclinical results show prevention of liver injury by histamine

Hepatitis - Publication highlights antiviral activity of NEUGENE antisense compound

Hepatitis - Viramidine 24-week data presented from chronic hepatitis C phase II trials

Hepatitis B Virus - Spread of hepatitis B viruses in vitro requires extracellular progeny

Hepatitis C - 1,000 patients enrolled in phase III hepatitis C trials evaluating Zadaxin

Hepatitis C - Study: Nearly 30% of hepatitis C treatment candidates not receiving therapy

Hepatitis C - Trial data of hepatitis C patients after liver transplantation presented

Hepatitis C - Trial results for NM283 for the treatment of HCV reported

Hepatitis C Vaccine - Hepatitis C-derived lipopeptides induced antibody-producing T cells

Hepatitis C Virus Therapy - Interactions between HCV NS5A protein and 2-tAS counteract interferon

Hepatology - Anti-GST autoantibody could be an early marker of autoimmune hepatitis

Hepatology - DEC2 is potent suppressor for hepatic cytochrome P450s opposing DBP

Hernia - 15q26.1-26.2 is candidate locus for congenital diaphragmatic hernia

Herpesvirus - Protein kinase inhibitors are promising herpesviruses inhibitors

Herpesvirus Vaccine - Gamma-herpesvirus 68 protects IFN receptor knockout mice from infection

High Cholesterol - Approval granted to market a generic version of simvastatin in U.K.

Hip Replacement - Cementless total hip arthroplasty feasible for elderly patients

Hip Replacement - Ultralok uncemented femoral prostheses effective for young patients

Hip and Knee Arthroplasty - William Beaumont Hospital to utilize PhDx Orthopedic Application

Home Health Care - Berkshire Asset Management opens first home health care operation

Hormone Replacement Therapy - Researchers say HRT may still offer important health benefits

Hospital Closing - California shuts down Rancho Cucamonga hospital over alleged violations

Hospital Error - Hospital fined for violations in heart transplant program

Human Growth Hormone - Use of human growth hormone for biomedical enhancement examined

Human Papillomavirus - Study compares HPV prevalence among Muslim and Hindu women in India

Hyperactivity - Food colorings and preservatives have "significant" impact on preschool children

Hyperbaric Treatment - Hyperbaric institute to be used for research, training

Hypertension - IL-1beta gene influences risk in Chinese men

Hypertension - Study counters perceptions about treating hypertension in blacks

Illegal Drugs - Lake Charles man pleads guilty to selling unapproved drugs

Imaging - Fischer Imaging to offer PACS and VIParchive technology

Imaging - Rotating camera puts fresh spin on coronary angiography

Imaging Technology - New mass spectrometry-based tissue imaging technology launched

Immune Suppressant - Everolimus safe and effective immunosuppressant in organ transplantation

Immunizations - Definition of vaccine advocacy and plan for action proposed

Immunnology - Mouse bone marrow contains large numbers of functionally competent neutrophils

Immunology - Autoantigen Tpr demonstrates nuclear envelope staining by indirect IFA

Immunology - CD25+ CD4 cells have a distinct IL-2R signaling pattern

Immunology - COX-2 inhibition and AT₁ R blockade treatment for chronic nephropathy

Immunology - Class II transactivator isoform regulates cathespsin E activity

Immunology - Combined tamoxifen-quercetin therapy eliminates prostate cancer tumors

Immunology - Cooperative pre-TCR and Notch signaling crucial for thymocyte maturation

Immunology - EBV latent membrane protein 2A triggers CD5+ B₁ cell development

Immunology - Epitope-specific sorting method improves scFv characterization

Immunology - Exposure of phosphatidylserine is not a primary signal for RBC removal

Immunology - Formation of disulfide bonds in Ig Fc assisted by protein-disulfide isomerase

Immunology - Grafted BM only variable associated with increased risk of CMV antigenemia

Immunology - High BAb and NAb titers reduce clinical efficacy of IFNbeta in RRMS patients

Immunology - Humanized agonistic anti-human 4-1BB mAb developed

Immunology - IL-10 promoter polymorphism associated with multiple organ dysfunction

Immunology - IL-21 is a switch factor for B-cell production of IgG₁ and IgG₃

Immunology - Interleukin concentrations vary in peritoneal fluid of women with endometriosis

Immunology - MRP8 and MRP14 re-expressed by tissue macrophages in chronic infection

Immunology - Magnitude of TCR engagement predicts T-cell state

Immunology - Model helps clarify why some get sick after TB infection, while others don't

Immunology - Neem leaf extract induces significant tumor reduction in Ehrlich carcinoma

Immunology - Neutrophil proteases may participate actively during acute inflammation

Immunology - Platelets can costimulate antigen-presenting cells

Immunology - Presentation of pathogen-derived antigens in vivo reviewed

Immunology - Regulatory role of Blimp-1 clarified

Immunology - Role of gammadelta T cells in defense against HSV-2 clarified

Immunology - Simulect use results in significant reduction in transplant rejection

Immunology - Standardized whole-blood leukocyte function assay validated

Immunology - T cell-induced Bcl10 degradation regulates NF-kappaB signaling

Immunology - T cells and macrophages main BAFF-expressing cells in salivary glands from pSS

Immunology - Toll-like receptor 2 ligand stimulates Th2 responses in vivo

Immunology - Toll-like receptor 7 recognizes single-stranded RNA viruses

Immunology - Various immune modulatory molecules induced in CD34⁺ hematopoietic cells

Immunology - Virus-specific regulatory T cells counteract anti-hepatitis C virus response

Immunotherapy - Integrin chains beta 1 and alpha v prognostic factors in metastatic melanoma

Implantable Devices - Breakthrough attributes of biothermal battery highlighted

Infection - Patient enrollment commences for PPI-0903 antibiotic phase I trial

Infection Control - $1.5B annual cost of surgical site infections can be reduced

Infectious Disease - Hepatitis E virus causes non-A, non-B, non-C acute hepatitis in Japan

Infectious Disease - Linezolid effective against VREF in premature infant

Infectious Disease - Re-infection with Wuchereria bancrofti is common in Tanzania

Inflammation - Tumors stimulate cytokines that trump distant repair mechanisms

Inflammatory Bowel Disease - Data presented on two gastrointestinal disease treatments

Inflammatory Bowel Disease - Probiotic VSL#3 improves symptoms of common complications in IBD, study shows

Inflammatory Demyelinating Polyneuropathy - Clinical trial investigates treatment of neurological disorder Gamunex

Influenza Virus - M1 matrix protein controls filamentous phenotype of influenza A virus

Influenza Virus - NP- and PB1-binding sites of influenza A virus PB2 protein identified

Information Tech - Clinical data sharing solution available for healthcare providers

Information Technology - Interactive obesity management program introduced

Information Technology - Modis selected to support military health system

Information Technology - President Bush says Vanderbilt's electronic record system a 'leading light'

Insulin Resistance - Contractions induce phosphorylation of AMPK site Ser⁵⁶⁵ in muscle

Insulin Resistance - Insulin resistance and hypertension reviewed

Insulin Resistance - Molecular regulation of SREBP function investigated

Insulin Resistance - Offspring of hypertensives have greater insulin resistance than controls

Irritable Bowel Syndrome - Company presents preclinical data on IBS drug candidate

Irritable Bowel Syndrome - IBS-D study patients experience relief of pain, discomfort with cilansetron

Irritable Bowel Syndrome - IBSTracker launched to study changing IBS marketplace

Irritable Bowel Syndrome - SynBiotic formulas launched to treat variety of gastrointestinal problems

Ischemic Heart Disease - Coronary perfusion flow is larger in diastolic than systolic arrest in rats

Ischemic Heart Disease - Perioperative beta blocker use is inconsistent in heart disease patients

Ischemic Heart Disease - Urban air pollution may increase the risk of dying in Norway

Japanese Encephalitis - In vivo electroporation increases efficacy of encephalitis vaccine

Kidney Transplant - Once-daily Valcyte prevents CMV after kidney transplant in study

Kidney Transplantation - Electronic monitoring provides optimal measure of immunosuppression adherence

Knee Replacement - Variables affecting post-TKA range of motion identified

Laboratory Techniques - Tools for reliable "gene chip" measurements in development

Legal Issues - Aetna withdrawing lawsuit against Abbott over AIDS drug

Legal Issues - Animal-rights activists charged in actions against testing lab in New Jersey

Legal Issues - British American Tobacco's actions at document depository hinder research

Legal Issues - CremaLita and city reach agreement on frozen dessert claims

Legal Issues - Hearing officer rules New Hampshire Governor's former volunteer must pay fine

Legal Issues - Inhaled nitric oxide gas and gas delivery devices lawsuit settled

Legal Issues - Iowa couple sues hospital for releasing pregnancy records

Legal Issues - Manufacturer of generic Vicoprofen comments on Court of Appeals decision

Legal Issues - Minnesota man pleads guilty in hormones case

Legal Issues - New York City says nine police officers sue over World Trade Center toxins

Legal Issues - Two more former Rite Aid executives sentenced

Legal Issues - U.S. Attorney General Ashcroft loses second legal battle over assisted suicide

Legal Issues - Utah couple sues companies over ephedra-based dietary supplement

Legal Issues - Woman settles discrimination case against county health department

Legislation - Law would increase drug costs for consumers, employers, pharmacy group says

Legislation - Venture capital money backs California stem cell measure

Leishmaniasis - HLA class II alleles play role in protection from leishmaniasis

Leukemia - American Hospital helps South American community achieve improved survival rates

Leukemia - Clofarabine trial in adult acute leukemia exceeds expectations, closed early

Leukemia - Highly aggressive natural killer-cell leukemia has a distinct phenotype

Leukemia - Study looks at marrow stem cells and chemotherapy

Licensing Agreement - Medicis closes license of ORAPRED, with option to purchase

Lipid Studies -  E. coli lipocalin Blc plays role in phospholipid binding

Lipid Studies - Expression of genes in differentiating adipocytes characterized

Lipid Studies - Hepatic steatosis not due to impaired fatty acid oxidation capacities

Lissencephaly - Neuronal arrangement in LIS1 and DCX lissencephaly may be different

Liver Cancer - Hepatocellular carcinoma regresses spontaneously in some instances

Liver Cancer - Proteomics can be useful in researching hepatic diseases

Liver Cancer - Regional chemotherapy for liver tumors appears promising

Liver Cancer - Study reviews modern hepatic imaging

Liver Failure - New scintigraphy test could aid preoperative assessment of liver function

Liver Regeneration - Hepatocyte growth factor required for efficient liver regeneration and repair

Liver Resection - Laparoscopic liver resection is safe and feasible

Liver Resection - Segmental approach to liver resection reduces intraoperative blood loss

Liver Transplantation - Numerical simulation model of hypothermic machine perfusion effective

Liver Transplants - Positive results reported in comparative Prograf trial

Liver Tumors - Benign liver tumors are found more frequently with abdominal imaging

Liver Tumors - Parental cigarette smoking increases children's risks of hepatoblastoma

Liver Tumors - Portal vein embolization can increase the safety of hepatic resection

Longevity - Obesity and an early death? No Sir!

Lung Cancer - Study points to the prospect of "individualized" cancer treatment

Lung Disease - Role of Toll-like receptors in lung disease reviewed

Lyme Disease -  B. burgdorferi CRASP-1 protein characterized

Lymphangiogenesis - Lymphatic vessel proliferation commences under inflammatory conditions

Macular Degeneration - Update provided on trials of Retaane 15mg for eye disease

Malaria Therapy - Malaria therapy in infants and childhood vaccinations studied

Malaria Transmission -  Plasmodium vivax transmission and control reviewed

Malaria Vaccine - Malaria prime boost vaccines reviewed

Male Factor Infertility - Round spermatid injection not useful in ART, study finds

Managed Care - New research shows national HMO enrollment at 70 million

Marijuana Use - Cancer patient gets 3 years probation for smoking marijuana

Market Analysis - 5-HT receptor antagonists will account for 52% of IBS market in 2013

Market Analysis - Attracting top clinical investigators requires careful planning

Market Analysis - Cardiovascular drugs represent $12.5B exposed to generics

Market Analysis - Clinical trials outsourced overseas save time, money

Market Analysis - Type 1 diabetes drug market to expand with insulin analogs, inhaled insulins

Mass Spectrometry - New protein ID system helps researchers pinpoint more proteins

Measles Vaccine - Influence of HLA-DRB1 alleles on immune responses to measles examined

Measles Vaccine - Maternal vaccine status affects placental transfer of measles antibody

Measles Vaccine - Number of infectious measles viruses in vaccines estimated by PCR

Measles Virus - Region involved in binding of measles virus H protein characterized

Medical - Mentor licenses patent covering method for treating urinary incontinence

Medical Care - Translation company to help with tests

Medical Devices - Electron holography facilitates study of MTJ microstructure

Medical Misconduct - Alabama doctor facing sex charges worked in Mississippi

Medical Misconduct - Police say nurse arrested on child porn was 'predator' who worked in a daycare

Medicare - Humana executive named to MedPAC

Melanoma Diagnosis - Proteomic evaluation yields possible uveal melanoma markers

Melanoma Vaccine - Enhanced tumor response to dendritic cells without CD8+ cells reported

Memory - Remembrance of smells past: How the brain stores those meaningful memories

Meningitis Vaccine - Meningococcal PorA protein induces bactericidal immune response

Meningococcal Vaccine - Meningococcal conjugate vaccines reviewed

Menopause - Patients can check their hormones with quiz

Menstruation - Chinese girls' premenarcheal expectations, postmenarcheal experiences compared

Mental Health - Arkansas ends treatment for mentally ill acquitted of crimes

Mental Health - Arkansas to end program, send mentally ill acquitted of crimes for private treatment

Mental Health - More suicides than homicides in New Jersey

Mental Health - Survey: Confidentiality concerns among barriers to seeking psychological care

Mergers and Acquisitions - Acquisition offer announced for Profile Therapeutics

Mergers and Acquisitions - Fisher announces expiration of waiting period under Hart-Scott-Rodino

Mergers and Acquisitions - Global E Bonds, Inc., announces the acquisition of APANI I

Mergers and Acquisitions - HCPro acquires nurse aide training provider

Mergers and Acquisitions - Hepatitis drug maker acquired

Mergers and Acquisitions - IVAX receives clearance of Polish antimonopoly office for acquisition

Mergers and Acquisitions - Intermagnetics to acquire maker of RF coils

Mergers and Acquisitions - Johnson & Johnson acquires Egea Biosciences

Mergers and Acquisitions - MediCor announces acquisition of breast implant company

Mergers and Acquisitions - Medical device firm acquired for $2 billion

Mergers and Acquisitions - Medical device supplier acquires medical manufacturing firm

Mergers and Acquisitions - Nutraceutical completes acquisition of supplement maker

Mergers and Acquisitions - Province Healthcare to acquire hospital in Las Cruces, New Mexico

Mergers and Acquisitions - Technology development company acquires Impedance Cardiography technology

Mergers and Acquisitions - Tennessee company buying LaPlace hospital

Metabolic Diseases - Abdominal fat increases FFA distribution to liver, especially in women

Metabolism - eIF4AIII binds spliced mRNA in the exon junction complex

Metastasis - Repeat radiotherapy offers children with metastatic bone cancer palliation

Metastasis - Response to transforming growth factor beta evolves as breast cancer progresses

Methamphetamine - METH increases dopamine transporter higher molecular weight complex formation

Microencapsulation - Antigen delivery by polylactide co-glycolide microparticles developed

Migraine Headache - Phase III program commences for novel migraine treatment

Modeling - 3D models being used to determine gene development in heart

Morphology - Structure of healthy, but obese, young women's hearts is different

Mucosal IBD - Results of Probactrix study presented at Digestive Disease Week

Mucosal Immunization - Mucosal immunization with cholera adjuvant offers long-term immunity

Multiple Sclerosis - Researchers identify basis for irreversible damage in MS

Muscular Dystrophy - Variable reduction of caveolin-3 found in patients with LGMD2B/MM

Mutagenesis - UV-induced intermediate stage oxidative stress maintains genomic instability

Myasthenia Gravis - Myasthenogenicity of Torpedo nAChR determined

Myelodysplastic Syndrome - New drug for myelodysplastic syndromes to be manufactured in Michigan

Myelodysplastic Syndrome - Trisenox and thalidomide produce multi-lineage hematologic responses in MDS

Myeloma - Simvastatin inhibits growth of cultured human myeloma cells

Myocardial Infarction - Less than half of heart attack survivors take beta-blockers after first year

Myocardial Infarction - New standard to help diagnose heart attacks developed

Myocardial Infarction - The thyroxine analog DITPA modifies post-infarction myocardial remodeling

Narcolepsy - Orexin peptides prevent cataplexy in narcolepsy model

Narcolepsy - Xyrem study for EDS in narcolepsy shows positive data across all measures

Nasopharyngeal Cancer - Brachytherapy after chemoradiation for nasopharyngeal cancer reported

Neisseria - Epithelial cell expression upon Neisseria infection studied

Neurodegeneration - Estradiol regulates estrogen receptor, GSK3, and catenin interactions

Neurodegenerative Diseases - Unexpected similarities between raindrops and proteins

Neurology - Brain cholinergic pathway regulates microglial activation through nAChR

Neurology - Reduced opioid sensitivity under neuropathic pain-like state elucidated

Neuroscience - Caspase-2 involved in selective neuronal cell death in HD in striatum and cortex

Neuroscience - Cerebral cavernous malformations stem from primary vascular defects

Neuroscience - Fluorescent labelling method facilitates 3-D imaging of cochlear tissues

Neuroscience - Glycoprotein deficiency enhances cortical neuronal excitability

Neuroscience - Immune activity may underlie neurologic discitis symptoms

Neuroscience - Microdialysis useful for monitoring cannabinoid influence on cAMP levels

Neuroscience - Novel microelectrode array can isolate individual neurons

Neuroscience - Pituitary tumors with D-2 receptor activity respond to cabergoline therapy

Neuroscience - Portable system enables field recordings of primate single neuron activity

Neuroscience - Tissue transglutaminase likely plays important role in neuronal function

Non-Hodgkin Lymphoma - Radiotherapy alone for early-stage NHL is inferior to chemotherapy

Non-Small Cell Lung Cancer - Cisplatin combined with weekly paclitaxel is active against advanced NSCLC

Nuclear Factor - IAP expression induces intestinal epithelial cells to resist apoptosis

Nuclear Medicine - Lobectomy followed by radioiodine manages differential thyroid cancer

Nutrition - Incentive-based intervention improves health status of children in Mexico

Nutrition - Very-low-fat diet decreases "good cholesterol," does not improve heart health

Obesity - Cardiology expert comments on diet studies

Obesity - StayWell Weight Management Solution Center launched

Obesity - Study: CLA helps overweight adults safely reduce body fat

Obesity Genomics and Genetics - Genetic determinants of obesity-related lipid traits outlined

Obesity Pathogenesis - Neuropeptide Y presynaptic actions reduced in obese rat hypothalamus

Obesity Pathogenesis - PPAR-gamma required in mature white and brown adipocytes for survival

Obesity Pathogenesis - Total ghrelin remains unchanged after short-term energy restriction

Obesity Risk Factor - Gourmet coffee consumption increases obesity risk in college women

Obesity Therapy - Amantadine did not affect weight gain induced by olanzapine

Obesity and Diabetes - Dietary protein impact on glycemic control during weight loss reviewed

Obstetrics - Eating some types of fish during pregnancy may protect baby from future asthma

Obstetrics - Ectopic pregnancy is uncommon in U.K.; cases have excellent prognosis

Obstetrics - Pregnant woman's asthma is likely to be worse if baby is a girl

Obstetrics - Radioimmunoassay developed to measure 3,3'-T2S in maternal serum

Obstetrics - Women who have children after age 45 likely to have had several pregnancies

Oncogenesis - Genetics show that aberrant mRNA translation may be related to cancer

Oncogenesis - Protein synthesis is necessary for oncogenic cellular transformation

Oncology - Drugs directed towards nuclear factor kappa B could assist chemotherapy

Oncology - Platelets reinforce tumor angiogenesis and invasion

Oncolysis - Autophagy is a newly recognized tumor suppressor modality

Ophthalmology - Check children under 5 early for vision problems

Ophthalmology - Expression and refolding of keratoepithelin in BL21 optimized

Ophthalmology - Wearable low-vision device gives the sight-impaired a cyber helping hand

Oral Cancer - Status of margins in mouth squamous cell cancer and recurrence examined

Organ Transplants - Registry data demonstrate superior long-term organ transplant outcomes

Orthopedic Surgery - Anterolateral mini-incision total hip replacement reviewed

Orthopedic Surgery - Posterior cruciate-retaining and posterior stabilized TKA compared

Orthopedic Surgery - Posterolateral minimal incision effective for total hip replacement

Orthopedics - Cementless femoral stem bone support compared with novel method

Orthopedics - Patient and tumor factors are reflected in synovial sarcoma survival rates

Orthopedics - Synthetic ligament prosthetic effective for recurrent THA dislocation

Orthopedics - Two acetabular cement pressurizers compared

Osteoporosis - Accurate bone-loss classification methods lacking

Osteoporosis - Bone anabolic agents revolutionize bone loss and bone disease therapies

Osteoporosis - Exercising after menopause may help reduce bone loss

Osteoporosis - New product launched for balloon kyphoplasty

Osteoporosis - Ospemifene effective in reducing bone turnover in postmenopausal women

Otorhinolaryngology - Novel technique improves outcome of laryngeal microsurgery

Ovarian Cancer - First case of complete remission reported

Ovarian Cancer - Inexperienced surgeons operate on most ovarian cancer patients in Maryland

Ovarian Cancer - LOH at chromosome 9q22-31 is a frequent, early event in ovarian tumors

Ovarian Cancer - Mechanism of enhanced TRAIL-mediated apoptosis hold treatment promise

Ovarian Cancer - U.S. Preventive Services Task Force recommends against routine screening

Ovarian Tumors - Ovarian cystadenofibromas can have malignant features on CT and MRI

Ovarian Tumors - The accuracy of frozen section in diagnosis of ovarian masses is generally good

Paget Disease - Single infusion of zoledronic acid effective in Paget disease trial

Paget Disease of Bone - Paget disease myopathy caused by mutant valosin-containing protein

Pain Medicine - Cold compresses effective for pain relief after total hip replacement

Pain Medicine - Doctors prescribe painkillers less often to African Americans, Latinos

Pain Medicine - Opioid receptors up-regulated in spinal cord of morphine-tolerant rats

Pain Therapy - Many patients take more pain relievers than recommended

Pain Treatment - FDA approves DepoDur for treatment of pain following major surgery

Pancreas - Pax2 mutant mice have increased numbers of islets of Langerhans

Pancreas Transplantation - Donor obesity does not affect outcome after cadaver pancreas transplant

Pancreatic Cancer - Pancreatic carcinoma reviewed

Paralysis - 19-year-old undergoes rare procedure to reverse paralysis

Parasitology - Gene encoding ribosomal protein of Taenia solium characterized

Parenting - Study shows that genes can protect kids against poverty

Patents - Broad U.S. patent issued for computational drug design technology

Patents - Company receives patent for LOMUCIN as mucoregulator

Patents - Genetics company receives two patents related to inflammation

Patents - Patent granted for germicidal device to prevent nosocomial infections

Patents - U.S. issued patent covers emollient-foam technology

Patient Care - 60 Michigan hospitals receive award for improving patient care

Patient Safety - N.J. hospital purchases Misys Optimum clinical information management solutions

Pediatric Cancer - RAS mutation status is not linked to acute lymphoblastic leukemia outcomes

Pediatric Cancer - Survey assesses complementary and alternative medicine among pediatric patients

Pediatric Cancer - Taiwanese parents whose children have cancer cope equally

Pediatric Obesity - Air pollution especially harmful to lungs of obese children

Pediatric Research - NIH awards Baylor, Texas Children's No. 1 spot in research funding

Penile Cancer - Penile carcinoma in developing world reviewed

Personnel - Allen Andersen named to board of supplement/personal care company

Personnel - Allina Hospitals & Clinics names new president

Personnel - Bioinformatics company adds personnel in business development and marketing

Personnel - Biopharmaceutical company appoints chief financial officer

Personnel - Biopharmaceutical company appoints new executive director, regulatory affairs

Personnel - Biotechnology company president and CEO appointed to BayBio board of directors

Personnel - CEO Ronald W. Dollens to retire after 32 years at Lilly, spin-off

Personnel - Canadian pharmaceutical firm nominates new member to board

Personnel - Cardiac diagnostics company announces election of new director

Personnel - Cline tapped as Oklahoma health secretary

Personnel - Device company reports resignation of chief financial officer

Personnel - Device firm names Ronald L. Greene as VP, sales and marketing

Personnel - Diagnostic imaging services provider announces new chief executive officer

Personnel - Drug discovery supplier hires Charles Powell as VP of sales, marketing

Personnel - E-learning company names Hugh Rienhoff and Thanos Triant to board

Personnel - Geneva B. Johnson appointed to VistaCare board of directors

Personnel - Gerard E. Puorro and Brian F. Sullivan join board of SonoPrepmaker

Personnel - HCA appoints Charles R. Evans eastern group president

Personnel - Japanese life sciences firm names new CEO

Personnel - Jasjit Suri, PhD, becomes director of applied R&D for imaging company

Personnel - Jeffrey Hatfield named CEO at pharmaceutical firm

Personnel - John Post named COO of company focused on neonatal and pediatric therapeutics

Personnel - Litx company names John Marshall to scientific advisory board

Personnel - Long-term acute care hospital announces new chief executive officer

Personnel - Marilyn O'Hara, American HomePatient, Inc.'s, CFO, to retire

Personnel - Mark Little elected to board; John Tarello retiring

Personnel - McGillicuddy elected chairman of WellChoice board

Personnel - Medical Staffing Network names Kevin Little president and COO

Personnel - Medical waste company taps Cummins as new CEO and president

Personnel - Michael Tognotti named director of sales at microarray company

Personnel - New chief executive officer to lead company in spinal implant product launches

Personnel - New president named at diagnostics firm, divestiture announced

Personnel - Palmetto GBA announces medical director of regional Medicare contract

Personnel - Patrick Balthrop named CEO of xMap company

Personnel - Pharmaceutical company announces changes to its board of directors

Personnel - Pharmaceutical company announces election of directors

Personnel - Pharmaceutical company announces new senior VP, commercial operations

Personnel - Pharmaceutical company appoints chief medical officer

Personnel - Pharmaceutical company elects John L. Higgins to board of directors

Personnel - Rolf Stahel named as nonexecutive chairman of immunology company

Personnel - Supplement maker collaborates with nutritional expert

Personnel - Thomas H. McLain named chairman of the board of StaphVAX maker

Personnel & Finance - Biopharmaceutical company elects directors, approves stock option plan

Pertussis Vaccine - Effect of pertussis vaccines on pulmonary immunology via aerosol reviewed

Pertussis Vaccine - Rapid purification method for pertussis toxin developed

Pharmacy Practice - Severe conditions drive consumers to brand medications over generics

Physician Practice - Chronic care medicine: Physicians say 'help'!

Phytotherapy - A new anthocyanin-rich berry extract suppresses cancer growth mechanisms

Pipeline Update - Neuroscience drug development firm emphasizes progress in clinical pipeline

Pneumonia - Phase III Trial for Tifacogin initiated

Poison Ivy Allergic Reaction - Pamphlet offers tips to prevent and treat allergic reactions to poison ivy

Polio Vaccine - Analysis of poliovirus isolates from patients and vaccinees reported

Polycystic Ovary Syndrome - Study suggests more women have PCOS than previously estimated

Post-Traumatic Stress Disorder - Prevalent mental health problems seen 3 years after NATO bombing of Serbia

Prenatal Testing - Novel technique brings prenatal testing from maternal blood closer to reality

Prescription Drug Cost - Panel hears arguments over cost of AIDS drug

Prescription Drug Costs - West Virginia Agency considers options to cut drug cost increases

Prescription Drugs - Stolen drugs weren't generic OxyContin

Preventative Medicine - Iowans taking more prescription heartburn pills

Primary Care Practice - GPs' beliefs about patients influence treatment

Prion Disease - Squalestatin cures prion-infected neurons

Privacy Issues - Attorney says he'll comply with court order in arsenic case

Prognostics - p53 over-expression correlates with local treatment failure in oral carcinoma

Prostate Cancer - Antioxidant system activation is important for prostate cancer patients

Prostate Cancer - Chromosome 16q analysis reveals tumor suppressor gene candidates

Prostate Cancer - FDA grants approval for Taxotere in prostate cancer

Prostate Cancer - Hormonal therapy and radiotherapy improve survival for prostate cancer patients

Prostate Cancer - Quality of life declines in the year before death in men with prostate cancer

Prostate Cancer - Registry to observe recurrent prostate cancer patients' management and outcomes

Prostate Cancer - Sexual disorders after radical prostatectomy involve the couple

Prostate Cancer - Study finds no connection between prostate cancer and atrazine exposure

Prostate Cancer - Zinc levels fall in prostate cancer cells with androgen-independent progression

Prostate Cancer Vaccine - Prostate tissue-specific vaccine candidate identified

Protein Kinase C - Mechanical pressure-induced phosphorylation of protein kinase reported

Proteomics - CREB binds to multiple loci on chromosome 22

Proteomics - Clinical proteomics is revolutionizing disease detection

Proteomics - Heightened tissue factor expression is implicated in oncogenic events

Proteomics - High-throughput assay measures tumor cell S-phase progression

Proteomics - Molecular perspectives on p97-VCP reported

Proteomics - Protein secondary structure analyzed by vacuum-UV circular dichroism

Proteomics - The N-terminal region of hepatitis C virus core protein generates nucleocapsids

Proteomics - Thrombomodulin localization in rat duodenum characterized

Pseudobulbar Affect - Symposium addresses pseudobulbar affect in geriatric patients

Psychotropic Drugs - Pediatric spending spike on drugs to treat behavioral problems

Public Health - Chronic diseases need global health attention

Public Health - World surveys find mental disorders highly prevalent and often untreated

Pulmonary - CE Mark approval granted new delivery system for surgical adhesive

Pulmonary Arterial Hypertension - Remodulin approved in Australia for treatment of pulmonary arterial hypertension

Pulmonary Fibrosis - Research: 55% of IPF patients may be initially misdiagnosed

Pulmonary Medicine - Hepatoma-derived growth factor encourages lung remodeling after injury

Pulmonary Medicine - Intraperitoneal nicotine alters lung morphometry in rodents

Pulmonary Medicine - Redox balance shifts remodeling processes during pulmonary hypertension

Quality Assurance - Concerns about California hospital surfaced a year ago

RNA Virus - Human DNA polymerase-eta is a reverse transcriptase

Radiation Therapy - Ceramide restoration overcomes cancer cell radioresistance

Radiology - Dangers of MRI in patients with neurostimulators reviewed

Radiotherapy - Exclusive distribution agreement signed for OneDose surface dosimeter

Receptor Studies - Expression of Notch receptors and ligands in the adult gut outlined

Receptor Studies - Histone acetylation level may be marker for chromatin structure

Receptor Studies - Patients with chronic lymphocytic leukemia host unique antigen receptors

Renal Disease - Phase I/II trial of E2F Decoy begins for prevention of AV graft failure

Renal Function - Myeloablation and autotransplant reverses renal failure in myeloma patients

Reproduction - Proteasomes in human sperm have extracellular localization

Reproductive Biology - Ceruloplasmin and iron interact during pregnancy, human study shows

Reproductive Biology - Protein expression studied in monkey endometrium

Respiratory Syncytial Virus - Respiratory syncytial virus proteins suppress induction of interferons

Restenosis - Carbon monoxide from smoking helps keep arteries open following angioplasty

Restenosis - Drug ineffective in reducing complications after irradiation

Restenosis - Implanted stents with c-myc suppressant engender arterial healing

Restless Legs Syndrome - Study says uncomfortable condition common cause of sleeplessness

Rheumatoid Arthritis - HLA-DQ/DR double transgenic mice are valuable as RA model

Rheumatoid Arthritis - Novel hypothesis of RA pathogenesis presented

Rheumatoid Arthritis - Phase I/IIa arthritis clinical trial results published

Rotavirus - Surveillance planned in Asia for devastating diarrheal disease in children

Rubella Virus - Rubella virus capsid protein modulates virus infectivity

SARS - Chinese scientists begin testing SARS vaccine on humans

SARS - New method may detect virus in minutes

Safety Equipment - DTAPS Protective suits certified for chemical/biological terrorism incidents

Salmonella - Anti-Salmonella typhi Vi ELISA developed

Salmonellosis - Reptile and amphibian contact increases risk of salmonellosis

Saphenous Vein Grafts - Rubicon Filter study in Europe yields positive 30-day follow-up results

Sarin - Company readies sarin-gas neutralizing enzyme for first responders

Sepsis - Novel porcine model of neonatal sepsis developed

Sepsis - Treatment may reduce mortality from major systemic infection

Sexual & Reproductive Health - British woman gave birth using 21-year-old frozen sperm

Sexual & Reproductive Health - Canada proposes access to "morning after pill" without a prescription

Skin Cancer - Retinoid-modulated proteins identified in squamous carcinoma cells

Skin Infections - Physician finds promise in study of novel injectable antibiotic

Sleep Apnea - Sleep Solutions announces agreements with U.S. Department of Veterans Affairs

Smallpox - The search for a safer smallpox vaccine: new data on promising candidate

Smoking Ban - Louisiana legislative panel snuffs out anti-smoking bill

Smoking Ban - Malibu City Council gives final approval to smoking ban on beaches

Spinal Cord Injury - Combination therapy dramatically improves function in rats

Spine Surgery - Analysis shows non-fusion spine procedure revenues to total $27M in 2005

Squamous Cell Cancer - Concomitant docetaxel, carboplatin, and radiotherapy treat head and neck cancer

Staffing - Diagnostics company enters strategic agreement with Physicians On-Call

Staffing - Healthcare unions urge mandatory overtime ban

Staffing - University of Maryland School of Medicine adding 100 scientists

Stem Cell Research - Cxcr4 receptor may exert trophic influences on precursor cell proliferation

Stem Cell Research - Evidence found for fusion between cardiac and skeletal muscle cells

Stem Cell Research - Interwoven mechanisms regulate endothelial progenitor cells

Stem Cell Research - Self-renewal capacity is a widespread property of neural crest precursor cells

Stem Cell Transplantation - Low-dose alemtuzumab reduces GVHD following myeloablative ASCT

Stem Cell Transplantation - Nipent may facilitate hematopoietic stem cell transplantation, study shows

Streptococcus - Streptococcal inhibitor of complement interactions investigated

Substance Abuse - Combination of drug therapies reduces cocaine use in primates

Substance Abuse - Drug dealers in eastern Kentucky beat pharmacists to new form of Oxycontin

Substance Abuse - Influence of prenatal cocaine exposure, home environment examined

Sudden Cardiac Death - FAMILION Test for genetic mutations associated with arrhythmia

Surgery - NIM-Spine System released; designed to reduce spinal-surgery risk

Surgical Technology - Anterior cervical plate system effective for cervical stabilization

Surgical Technology - NICE guidance has limited effect on procedure performances

Surgical Technology - Painless suction drain removal technique developed

Synovial Sarcoma - Factors predicting synovial sarcoma recurrence and metastasis reported

Systemic Lupus Erythematosus - Company reports first clinical results with epratuzumab in lupus

Tachyphylaxis - Motilin agonists show minimal tachyphylaxis in preclinical models

Thromboembolism - Venous thromboembolism is a well-known complication affecting cancer patients

Thyroid Tumors - Cyclin D1 overexpression is significant in thyroid tumors

Tissue Donation - FDA sets new rules on who can donate human tissue

Tissue Engineering - Crosslinking determines degradation rate and regeneration of acellular tissue

Tissue Engineering - Denatured collagen used as support for FGF-2 delivery system

Tobacco Policy - Japan Tobacco's strategies regarding evidence of tobacco health harms

Tobacco Use - Fewer students smoking as prices increase

Tobacco Use - Surgeon general expands list of diseases linked to smoking

Transfection - Expression system secretes TAT fusion proteins

Transfusion Medicine - Method developed to measure red blood cell survival following transfusion

Transgenics - Cx36-EGFP associated with AMPA-type glutamate receptor subunit GluR1

Transplant Medicine - Adult living donor liver transplantations have been slow to gain acceptance

Transplant Medicine - Center for International Blood and Marrow Transplant Research created

Transplant Medicine - Hepatocyte growth factor expands outcomes after islet transplantation

Transplant Medicine - High schooler graduating on 18th anniversary of liver transplant

Transplant Medicine - Insight into transplant rejection might lead to novel prevention therapies

Transplant Medicine - Research may reduce blood clot formations in artificial organs

Transplant Medicine - Study may improve survival of transplanted livers

Transplantation Medicine - LEA29Y may provide new option for preventing organ rejection

Transplantation Medicine - Recovery after HCT for leukemia or lymphoma can take 3-5 years

Treacher Collins Syndrome - Additional exons linked to Treacher Collins syndrome gene reported

Tremors - Phase III study of Altropane to differentiate tremors

Trial Management - LifeTree and PHT announce business development alliance

Tumorigenesis - Chromosome segregation and genomic stability may be related to tumorigenesis

Tumorigenesis - Rosmarinic acid inhibits epidermal inflammatory responses

Tumorigenesis - Sodium gluconate protects animal models from large bowel cancer

Tumorigenesis - Stat3 activation may be a critical event during skin tumor promotion

Type 1 Diabetes - Immune cells may play important role in progression of diabetes

Type 1 Diabetes Pathogenesis - No link found between NeuroD gene variants and type 1 diabetes

Type 2 Diabetes - Diabetes study demonstrates new paradigm for finding disease-associated genes

Type 2 Diabetes - Inositol hexakisphosphate helps regulate beta-cell protein phosphatases

Type 2 Diabetes Pathogenesis - Hypothesis for type 2 diabetes pathogenesis proposed

Ulcerative Colitis - Daclizumab does not meet primary endpoints in ulcerative colitis trial

Ultrasound - Company launches new line of ultrasound probes for the replacement market

Urinary Tract Infection - Conditions favoring E. coli cause greater UTI risk in some diabetics

Uterine Fibroid Tumors - Effective radiation dose calculated for uterine artery embolization

Vaccine Adjuvant -  Asparagus racemosus extract shows potential as vaccine adjuvant

Vaccine Adjuvant - Host factors affecting response to vaccine adjuvants reported

Vaccine Development - DNA shuffling and screening technologies overcome antigenic diversity

Vaccine Development - Method to load antigen-presenting protein with glycolipids developed

Varicella Vaccine - HMO varicella vaccination program decreases incidence of varicella

Vascular Disease - Evidence could indicate bacteria-like etiology of vascular calcification

Vasculopathy - Epidermal progenitor cells help restore blood flow in diabetic ischemic limbs

Vector Development - Herpesvirus-based vector systems provide for efficient transduction

Ventilator-Associated Pneumonia - Company gets grant for development of P. aeruginosa vaccine

Vertical Disease Transmission - Chemokine receptor may not play direct role in placental HIV transmission

Veterans Care - Veterans officials to build clinics, add psychiatric beds

Viral Assembly - Lysine 72 acetylation influences hepatitis delta virus RNA synthesis

Virology - Book says monkey virus contaminated polio vaccine

Virology - Hepadnavirus assembly diminishes with impaired protein glycosylation

Virology - Human lymphocytes not susceptible to simian virus 40 infection

Virology - Study suggests double punch could more efficiently kill viruses

Virology Vaccine - Cytokine responses to inactivated viruses fail to default without IL-12

Water-Borne Illness - Silver plus UV radiation may prove more effective at disinfecting water systems

Weight Loss - Randomized trials study low-fat vs low-carbohydrate diets for weight loss

West Nile Virus - Arkansas town rolls out new ordinance for West Nile prevention

West Nile Virus - First confirmed case of West Nile virus in Los Angeles County mosquitoes

West Nile Virus - New Mexico has first human West Nile case of 2004

West Nile Virus - North Dakota State Univ. lab to start testing for West Nile

West Nile Virus - Scottsdale, Arizona, goes after disease-carrying mosquitoes

West Nile Virus - Survivors tell of crippling pain, sleepless nights

West Nile Virus - West Nile cases confirmed in Arizona, New Mexico; bad season ahead?

West Syndrome - Guideline evaluates treatment of infantile spasms

Women's Health Research - Group hails introduction of Women's Health Office Act

Wound Care - V.A.C. GranuFoam Heel Dressing earns APMA seal of approval