Health and Medicine Week

Complementary & Alternative Medicine - Licorice extract significantly improves learning and memory

SARS - Physicians, nurses treating SARS patients at high risk of developing the disease

Sudden Cardiac Death - Heart enlargement is a common cause of sudden death in young people

Vascular Disease - Surgery best option for preventing recurrence of venous leg ulcers

AIDS Vaccine - Volunteers needed as more AIDS vaccines move into clinical trials

Abnormal Uterine Bleeding - Clinical trial compares hysterectomy with medical treatment

Abortion Ban - Federal judge says partial-birth abortion ban infringes on right to choose

Acute Coronary Syndrome - FDA clears new intended uses for Troponin T test

Adolescent Cancer - Researchers compare experiences with starting an adolescent cancer unit

Adverse Drug Effects - Lupus-like syndrome linked to simvastin therapy

Allergies - Full enrollment reported in phase II/III AIC trial

Allergy & Immunology - PAR-2-mediated activation enhances airway inflammation

Allergy Medicine -  Dermatophagoides atopy patch tests are highly reproducible

Allergy Medicine - Allergy to ovalbumin induces lymphocyte migration to intestinal mucosa

Allergy Medicine - PAF responsiveness in subjects with plasma PAF acetylhydrolase deficiency

Allergy Medicine - Test methods evolving for newly emerging allergy epidemics

Alzheimer Disease - Beta-secretase modulates processing of APLP2 in vivo

Alzheimer Disease - Carboxyl-terminus of amyloid protein precursor needed to activate MAPK

Alzheimer Disease - Deactivation of two genes could be the cause of AD

Alzheimer Disease - Diffusion tensor imaging detects white matter changes in mouse model

Alzheimer Disease - Estrogen receptor changes in hypothalamus are related to AD neuropathology

Alzheimer Disease - Hypoxia remodels Ca2⁺ homeostasis in type I cortical astrocytes

Alzheimer Disease - Increased level of beta-amyloid found in brains of bulbectomized mice

Anemia - Successful cord blood stem cell transplant reported

Anesthesia - Cox-2 inhibitors reduce complications after laparoscopic surgery

Angiology - Endovascular management effective for iliac vein occlusive disease

Angiology - Nitric oxide and GABA mediate adrenomedullin's hypotensive effects in brain

Angiology - Study of decellularized carotid artery vascular grafts released

Angiology - TAL-1 stimulates endothelial cell migration and morphogenesis

Anorexia - Megestrol acetate improves appetite and weight gain in cancer and AIDS patients

Anthrax - Handheld sensor offers anthrax detection capabilities for first responders

Anti-Infectives - Polycomplexes of poly(acrylic acid) and streptomycin sulfate characterized

Antibacterial Research - NMR evidence found for independent domain structures in zoocin A

Antibiotics - Antibiotic activity of field-collected Streptomycetes characterized

Antibiotics - Biopharmaceutical company announces additions to fungicide patent portfolio

Antibiotics - FDA approves amoxicillin and clavulanate potassium for oral suspension

Antidepressants - Serotonin increases neurotrophic factor release in glioblastoma cells

Antimicrobials - Structural motif of alpha-helical antimicrobial peptides identified

Antiphospholipid Syndrome - Endothelial microparticles may play role in thrombotic complications of APS

Apoptosis - Caspase-mediated cleavage of syntaxin 5 and giantin occurs in apoptosis

Apoptosis - Granzyme B encoded by RAH allele retains pro-apoptotic activity

Apoptosis - Labeled Annexin A5 detects programmed cell death in vitro and in vivo

Apoptosis - TopBP1 recruits Brg1/Brm to repress E2F1-induced apoptosis

Arrhythmia - New cardiac syndrome identified

Arthritis - Surprising new evidence highlights adverse effects of vitamin C on arthritis

Artificial Heart - Man-made heart provides woman new lease on life

Aspergillus - Method for purification of Aspergillus niger xylanase developed

Aspergillus - Production of melanin by Aspergillus fumigatus reviewed

Assisted Reproduction - Low-dose luteinizing hormone boosts ovulation but mitigates hyperstimulation

Assisted Reproduction - Medically assisted reproduction still risky in presence of chronic viral disease

Asthma - Alvesco (ciclesonide) has no effect on HPA-axis function

Asthma - Clinical trial to evaluate Xolair in pediatric allergic asthma patients

Asthma - FDA approves ANDA for Terbutaline Sulfate Injection

Asthma - Gene at root of urban air pollution's lung effects

Asthma - Neighborhoods may influence whether residents have asthma

Asthma - Study explores link between depression, anxiety and asthma in children

Asthma - Xopenex improves FEV₁ more than racemic albuterol in study patients

Atherosclerosis - PAD patients should be aggressively treated for atherosclerotic risk factors

Atherosclerosis - Vulnerable atherosclerotic plaque identified with novel texaphyrin compounds

Atherosclerotic Disease - Vitamin E in dialysis fluid may reduce endothelial damage

Atrial Fibrillation - Enrollment completed in first stage of atrial fibrillation study

Autoimmune Disease - Decreasing estrogen levels prompt increase in inflammation-regulating antibody

Autoimmune Disease - ELISA for detection of autoantibodies to BP230 developed

Autoimmune Disease - Mice made to express liver cell osteopontin model human autoimmune hepatitis

Avian Influenza - Biotech firm to make flu vaccine for U.S. National Institutes of Health studies

Avian Influenza - NIAID announces contracts to develop vaccine against H5N1 strain of bird flu

Awards - 2004 Analytical Instrumentation Company of the Year named by Frost & Sullivan

Awards - St. Mary Medical Center of Pennsylvania named one of U.S.'s 100 top hospitals

Back Pain - Virtual reality program to teach doctors, therapists about human back problems

Bacterial Meningitis - Choroid plexus involved in host defense

Bacteriology - Histopathologic changes in kidney and liver correlate with SPE B production

Bacteriology - White tea has an inhibitory effect on various pathogenic bacteria

Bardet-Biedl Syndrome - Oligogenic properties of Bardet-Biedl syndrome reviewed

Benign Prostatic Hyperplasia - FDA warning letter clarified by biotech firm

Bioengineering - 2'-O-methyl- groups stabilize the binding of phosphorothioate antisense ODNs

Bioengineering - Cell matrix-modified implants stimulate new vessel growth in animals

Biomarker Discovery - Advanced multiplexed protein labeling technology described

Biotechnology - Cytokine flow cytometry assesses cellular immune responses to viral antigens

Biotechnology - Glassy carbon microchip developed for electrospray mass spectrometry

Biotechnology - Microfluidic device enables rapid particle separation

Biotechnology - Splicing human genes into plants regains favor

Bioterrorism - Ohio hospitals will help monitor for signs of terrorist attack

Bladder Cancer - Carbonic anhydrase IX predictive of outcome in bladder cancer

Bladder Prolapse - FDA clears minimally invasive treatment for bladder condition

Bleeding - Application submitted to FDA to market autologous thrombin processing device

Blood Banking - Autologous FG by CryoSeal FS System suggestive for hypothetical blood saving

Blood Screening - Consensus determines principles of screening and prevention of vCJD

Blood Vessel Formation - Phase I trial of ATN-224 initiated in patients with solid tumors

Bovine Spongiform Encephalopathy - Japanese, U.S. scientists develop mad cow-resistant cow for medical research

Brain Cancer - Bispecific immunotoxin effective in murine model

Brain Cancer - Microspheres developed for 5-FU delivery to brain

Brain Cancer - RNAi delivery system crosses blood-brain barrier to target brain tumors

Breast Cancer - Adding Herceptin to chemotherapy regimen boosts response rates in early disease

Breast Cancer - Advanced diagnosis more likely for deprived women in the U.K.

Breast Cancer - Aromasin after Tamoxifen lessens breast cancer recurrence in study

Breast Cancer - Breast clinic established in Sri Lanka

Breast Cancer - Changing practices may raise African American women's cancer risk

Breast Cancer - Chemotherapy including epirubicin may improve survival for some patients

Breast Cancer - Concordance between HER-2 testing methods determined

Breast Cancer - Drug shrinks tumors or slows growth in up to half of women

Breast Cancer - Epirubicin and paclitaxel activity independent of adjuvant therapy

Breast Cancer - FDA grants approval for Gemzar in combination with Taxol

Breast Cancer - Gemcitabine/paclitaxel combination extends patients' overall survival

Breast Cancer - Gene expression ratio identifies recurrence risk in patients receiving tamoxifen

Breast Cancer - Gene mutation, use of certain antidepressants may decrease tamoxifen's effects

Breast Cancer - High school student adds to understanding of BRCA-1 gene

Breast Cancer - Increased false-negative rates reported with new breast cancer staging system

Breast Cancer - Mammography continues to be a highly effective screening tool

Breast Cancer - Online support improves psychosocial therapy for breast cancer patients

Breast Cancer - Overview of neoadjuvant endocrine therapy for breast cancer published

Breast Cancer - Patient's needs in follow-up after breast cancer therapy discussed

Breast Cancer - Possible new mechanism suggested for estrogen's promotion of disease

Breast Cancer - RT-PCR for mammaglobin genes detects sentinel lymph nodes micrometastases

Breast Cancer - Study looks at effect of reproductive factors and lactation on CIS risk

Breast Cancer - Tamoxifen stimulates tumor growth following alteration of estrogen receptor

Breast Cancer Survival and Mortality - CD105 identifies node-negative breast cancer patients with poor prognoses

Breast Cancer Therapy - Radiation and subsequent TRAIL/Apo-2L quells breast tumor xenografts in mice

Breast Cancer Vaccine - Electroporated DNA vaccine clears breast cancer in transgenic mice

Breastfeeding - Lactation intervention-program boosts breastfeeding

Business & Finance - Biopharmaceutical company achieves second milestone of license agreement

Business & Finance - Biopharmaceutical company announces participation in NASDAQ Biotechnology Index

Business & Finance - Biopharmaceutical company reports loss of $0.02 per share

Business & Finance - Biotechnology company receives first success-based milestone payment

Business & Finance - Device firm announces completion of a $35M series C financing

Business & Finance - Tenet sells acute care hospital in Barcelona, Spain, to BC Partners Ltd

Business Update - ASU, Mayo Clinic partner for research

Business Update - Collaboration to develop various dosage forms of cephalosporin antibiotics

Business Update - Detroit Medical Center hires five new heart doctors to boost cardiology program

Business Update - Dow Corning emerges from bankruptcy

Business Update - Drug developer to realign product development strategy

Business Update - Genetic manufacturing company relocates

Business Update - Pharmaceutical company announces new name and ticker symbol

Business Update - Portfolio of OTC and personal care brands acquired from Pfizer

Business Update - Pozen shares plummet after migraine drug rejected

Business Update - Sierra Vista hospital gets certification for newborn care

Business Update - Triad Hospitals, Inc., to sell acute-care hospital in California

Business Update - U.K. pharmaceutical company to establish U.S. headquarters in Pennsylvania

Business Update - Universal Health Services, Inc., to sell Louisiana hospital

Business Update - Utah charity files for bankruptcy as probe continues over sale of fitness equipment

Business Update - Weight Loss Forever signs agreement for four new franchises

Cancer - First Minnesota hospital to use robot-assisted technology in prostate cancer surgery

Cancer - Life sciences research and information company launches new publication

Cancer - Ligand-based VTA technology presented at international conference

Cancer - Phase II clinical studies to study Pivanex in leukemia and melanoma

Cancer - Scope of breast duct to be distributed in the Middle East

Cancer Cell Biology - Perpetual cancer from leukemic stem cells described

Cancer Cell Biology - Researchers pinpoint unlikely ally in cancer fight

Cancer Diagnosis - Immunomagnetic separation depicts esophageal cancer micrometastasis

Cancer Diagnostics - S100C staining may aid diagnosis of thyroid lesions

Cancer Genetics - BRCA1/2 mutation spectra determined in Belgian breast/ovarian cancer families

Cancer Prevention - Men are dodging the doctor when cancer symptoms appear

Cancer Prognosis - High levels of serum VEGF predict poor outcomes after liver cancer therapy

Cancer Recurrence - The management of recurrent cancer after prostatectomy is not clear cut

Cancer Research - CEACAM6 crosslinking leads to increased extracellular matrix component adhesion

Cancer Risk - Exposure to light at night may increase cancer risk

Cancer Screening - Prostatic adenocarcinomas can be detected in men with low PSA values

Cancer Therapy - Algal toxin may disrupt the tumor fighting functions of E-cadherin

Cancer Therapy - Amifostine does not protect lungs from carmustine-containing chemotherapy

Cancer Therapy - Cannabis may help nausea, pain, and spasticity

Cancer Therapy - Electrochemotherapy may be a new treatment for solid tumors

Cancer Therapy - Genetically engineered virus targets "selfish" cancer cells

Cancer Therapy - Marine sponge Homaxinella sp. yields new cytotoxic metabolites

Cancer Therapy - New radiation safety audit program for a research institution is successful

Cancer Therapy - Radiotherapy toxicity linked to abnormal transcriptional responses to DNA damage

Cancer Therapy - Scientists block cellular enzyme activity involved in cancer progression

Cancer Therapy - The thalidomide analogue CC-5013 uses T-cell induction to fight cancer

Cancer Treatment - Study into suspected cancer cluster moves forward

Cancer Treatment - Utah doctors determine 'good, bad' chemo

Cancer Vaccine - Melanoma cells expressing CD83 induce antitumor immunity

Cancer Vaccine - NY-ESO-1 protein protects against NY-ESO-1+ tumors

Cancer Vaccine - Researchers turn tumor cells in situ into tumor epitope-presenters

Cancer-Related Anorexia - Study reviews cancer-associated anorexia

Candida Vaccine -  Candida albicans strain protects against systemic candidiasis

Carcinogenesis - Study cautions about compounds produced during cooking of meat, fish

Carcinogens - Exposure route dictates lung cancer type after arsenic contact

Carcinogens - New animal models show the carcinogenic synergy of UV radiation and arsenic

Cardiac Monitoring - Housecall Plus remote monitoring system launched

Cardiology - 30-day safety data available for coronary stent

Cardiology - Cardiology imaging and information company to manage stent trial

Cardiology - Cigarette smoking predicts reduced maximal FEV1 level in males but not females

Cardiology - E.U. approves two heart disease treatments

Cardiology - FDA issues marketing clearance for cardiac flat-panel detector

Cardiology - Heparin coating protects blood during open-heart procedures

Cardiology - Intrinsic implantable cardioverter-defibrillator now available in Europe

Cardiology - L-type calcium channel subunit expression clarified in developing heart

Cardiology - Medtronic launches InSync cardiac resynchronization therapy system in Japan

Cardiology - New clinical data on stent performance announced

Cardiology - New report shows diagnostics driving cardiovascular market

Cardiology - Potential treatment for aortic aneurysm repair surgery given FDA fast track status

Cardiology - Recreation of published results may confirm nanobacteria in arteries and valves

Cardiology - Technology company invests in catheter-based technology for heart valve repair

Cardiovascular Disease - Heat-inactivated C. pneumoniae is not atherogenic

Cardiovascular Disease - Homocysteine added to Poly-Chem analyzer testing menu

Cardiovascular Disease - Impaired apoptotic cell clearance enhances atherogenesis and autoimmune disease

Cardiovascular Disease - Lipophilic compounds in tomatoes protect against cardiovascular disease

Cardiovascular Disease - Metabolic syndrome positively associated with cardiovascular disease

Cardiovascular Disease - Moderate hepatic impairment has limited effect on azimilide pharmacokinetics

Cardiovascular Disease - Uric acid levels may be linked to cardiovascular risk factors in old Korean men

Carotid Stenting - CE Mark approval issued for Protege GPS Nitinol Self-Expanding Stent

Cell Biology - Cells from fat tissue turned into functional nerve cells

Cell Biology - Malaria parasite's cellular "choreography' prolongs infection

Cell Biology - Nck and Crk adaptor proteins modulate VEGF-controlled cell migration

Cell Biology - Therapeutic strategies targeting telomere maintenance defeat immortality

Cervical Cancer - HPV oncoproteins expressed by foreskin cells alter the angiogenic environment

Cervical Cancer - Optical diagnosis of cervical dysplasia on the horizon

Cervical Cancer - Study compares radiation treatments

Cervical Cancer - Study findings support 2001 ASCCP disease management guidelines

Cervical Cancer - Three algorithms summarize management of low-grade SIL

Cervical Cancer - Women in Finland with 5+ children have higher risk of cervical cancer

Childhood Immunization - More work needed on national immunization registry

Childhood Immunization - Vaccines don't increase risk for asthma, eczema

Childhood Obesity - After school activities can reduce obesity among inner city youth

Childhood Obesity - Coping style in childhood not affected by obesity

Chirality - Method to determine chirality determination of amino acids developed

Chlamydia - Glycosaminoglycans protect against Chlamydia infection in vitro

Cholesterol - Cholesterol regulates GCase activity/stability in Niemann-Pick disease type C

Chronic Bronchitis - Avelox promotes rapid remission of chronic bronchitis symptoms in study

Chronic Constipation - Zelnorm demonstrates safety and efficacy in chronic constipation studies

Chronic Diseases - Beech Street launches disease management program

Chronic Hepatitis C - Diligence is important for managing patients with hepatitis C virus infections

Chronic Lymphocytic Leukemia - Rituximab called most promising emerging drug for chronic lymphocytic leukemia

Chronic Myeloid Leukemia - A few questions remain concerning chronic myeloid leukemia

Chronic Obstructive Pulmonary Disease - Tiotropium Bromide Inhalation Powder recommended for COPD in ATS guidelines

Cochlear Implant - Effects of pulse rate on Clarion cochlear implant performance determined

Cochlear Implants - Cochlea is surgically accessible through middle cranial fossa

Cognition - Cognitive performance varies after radiation therapy for brain tumors

Cognitive Function - Need for sleep indicates underlying cellular demands

Collaborations - $1.2M study awarded for cardiac safety monitoring

Collaborations - Cardiac-related software development and license agreement signed

Collaborations - Distribution agreement with ArthroCare completed

Collaborations - Exclusivity rights to 150mg generic Zyban relinquished

Collaborations - FTC clears reacquisition of intranasal influenza vaccine products

Collaborations - License agreement with Celera Diagnostics expanded

Collaborations - Licensing agreement signed to develop, market Lumigan in Japan

Collaborations - Option granted for rights to blood platelet modification technology

Collaborations - Pandemic influenza vaccine agreement signed

Collaborations - Pharmaceutical firm gets $21M award under expanded agreement

Collaborations - Rights acquired to retinoid portfolio

Colon Cancer - Multiple local IL-2 treatments effective in mice

Colon Cancer - Nitric oxide rules colon carcinoma angiogenesis markers differentially

Colorectal Cancer - Bio-pathological profile is prognostic in colorectal adenocarcinomas

Colorectal Cancer - Emotional support helps colorectal cancer patients make treatment decisions

Colorectal Cancer - Expression of p185 protein has prognostic value

Colorectal Cancer - Flavaglines induce apoptosis in colorectal cancer cells

Colorectal Cancer - Oral PSK with UFT reduced recurrence in colorectal cancer

Colorectal Cancer - Treatment options for liver metastases from colorectal cancer outlined

Common Cold - Low outdoor air supply in buildings increases exposure risk to cold viruses

Complementary & Alternative Medicine - Faith-based programs can improve health

Complementary and Alternative Medical -  Ganoderma lucidum slashes the growth of human prostate cancer cells

Compliance - Many don't get full dose of chemo

Congenital Heart Disease - Mouse model of Down syndrome has congenital heart disease

Congestive Heart Failure - Data published on study of blood volume measurement

Congestive Heart Failure - Study seeks to improve quality of life for heart failure patients

Constipation - Constipation treatment has no rebound effect after discontinuation

Contraception - Study finds no benefit to OCs for 2 months prior to ovarian hyperstimulation

Cornelia de Lange Syndrome - Researchers discover gene that causes rare disorder

Coronary Artery Bypass Surgery - Intraoperative metoprolol does not improve beta-adrenergic receptor function

Coronary Artery Disease - ABT-578-eluting stents may inhibit restenosis

Coronary Artery Disease - Carvedilol may reverse MDR1/P-glycoprotein-mediated multidrug resistance

Coronary Artery Disease - Coating and drug-eluting technology licensed for coronary stent system

Coronary Artery Disease - Socioeconomic status may be linked to heart disease

Coronary Blockage - Diabetic patients benefit from Cypher Sirolimus-eluting coronary stent

Coronavirus - Previously undescribed coronavirus associated with respiratory disease in humans

Correctional Health - Prison system's spiraling healthcare costs examined

Critical Care Medicine - Factors predictive of postextubation stridor identified

Critical Care Medicine - Radiologic-assisted endotracheal intubation described

Critical Care Medicine - Referrals to palliative care services should consider a patient's needs

Crohn Disease - Antegren to be submitted for approval in Europe

Crosslinking - RPA binds primer-template junction in absence of its major ssDNA-binding domains

Cystic Fibrosis - Patent application filed for potential cystic fibrosis treatment

Cytomegalovirus - Inverse correlation between CD27 quantitation and cytotoxic effector function

DNA Research - 53BP1 links DNA damage response to Ig heavy chain class-switch recombination

DNA Vaccine - Inoculation of plasmid DNA induced expression of LacZ gene

Dementia - Virologist receives NIH grant to continue investigation of HIV dementia complex

Dengue Fever - IgG avidity test can distinguish primary from secondary dengue infections

Depression - NIH awards $1.8 million for study on coping with HIV/AIDS

Dermatology - Lanceolate hair rat phenotype results from missense mutation

Dermatology - Nephrogenic fibrosing dermopathy characterized

Detection - RAPD analysis useful for genotyping clinical Candida spp. isolates

Diabetes Pathogenesis - B cell selection defects promote diabetogenic antigen-presenting cells

Diabetes Pathogenesis - Bovine serum albumin in cow's milk not likely cause of diabetes

Diabetes Pathogenesis - Cytokine disruption shared by macrophages from diabetic and lupus mice

Diabetes Pathogenesis - IL-10-resistant PGS2 expression found in type 1 diabetic monocytes

Diabetes Pathogenesis - Increased islet antigen presentation leads to type1 1 diabetes

Diabetes Pathogenesis - Prior 5-HT exposure on rat islet insulin responses investigated

Diabetes Research - New DNA technology used by tissue-banking firm to study diabetes

Diabetes Therapy -  Fraxinus excelsior and Silybum marianum are hypoglycemic

Diabetes Therapy -  Syzigium cumini seeds are antidiabetic and antihyperlipidemic

Diabetes Therapy - Diabetes in older adults reviewed

Diabetes Therapy - K+ stimulates proinsulin biosynthesis in rat pancreatic islets

Diabetes Therapy - Language used in relation to diabetes may undermine therapy efforts

Diabetic Nephropathy - Rapid change in glucose level aids mesangial cell proliferation

Diagnostic Imaging - PET may become invaluable for diagnosing and treating brain tumors

Diagnostics - Adaptive mechanical index can shorten color blooming in Doppler flow imaging

Diagnostics - Agreement adds positron emission tomography to medical center's imaging menu

Diagnostics - Automated schistocyte counting method evaluated

Diagnostics - FDA requests and approves new name for infection imaging product

Diagnostics - Flow cytometry is utilized to study natural killer T cells

Diagnostics - Impalpable prostate tumors should be graded T1c regardless of TRUS visibility

Diagnostics - In vivo bioluminescence imaging reveals tumor elements in animal models

Diagnostics - Lab-on-a-chip detects ammonia in human breath

Diagnostics - Metastases may not always come from the primary tumor

Diagnostics - Method to minimize interference of silver staining with MS developed

Diagnostics - Molecular assay detects RSV, influenza, and parainfluenza viruses

Diagnostics - New ClinProt products launched for proteomics, biomarker discovery

Diagnostics - Radioiodinated MMP inhibitor tracers may enhance tumor imaging

Diet & Nutrition - Dietitians issue position statement on women's nutritional needs

Diet and Nutrition - Arabinogalactan offers no long-term benefits on serum lipids or glucose

Diet and Nutrition - Dietary proteins in regulation of food intake and body weight reviewed

Diet and Nutrition - S-adeno-syl-L-methionine in dietary supplements characterized

Diet and Nutrition - n-3 Fatty acid supplements raise exercise levels in pancreatic cancer patients

Disease Diagnostics - New agreement will help develop diagnostic tests in oncology and other diseases

Disease Prevention - North Carolina House bill would extend health isolation periods

Domestic Violence - Training video helps health professionals help pregnant victims

Drug Access - New campaign against reimportation launched

Drug Advertising - FDA warning letter issued on promotional materials for Advate

Drug Approval - New survey highlights FDA's successes and failures

Drug Delivery - Behavior of drug-loaded "microballoons" in stomach characterized

Drug Delivery - Biodegradable thermoplastic depot maintains camptothecin stability

Drug Delivery - Chitosan membrane shows promise for transdermal dosing

Drug Delivery - Crystallization of NEA in transdermal patch characterized

Drug Delivery - Gel-entrapped tamoxifen offers sustained drug release at tumor sites

Drug Delivery - New drug delivery system allows for combination of drugs

Drug Delivery - Optimal conditions determined for impinging jet-based drug dispersal

Drug Delivery - PLGA microspheres suitable for ocular peptide delivery

Drug Delivery - Patent awarded for new measurement system for pharmaceutical sprays

Drug Delivery - Scientists smuggle drugs into tumors

Drug Delivery - Transdermal Delta₈ -THC system developed

Drug Development - Advances in understanding autism may lead towards effective treatment

Drug Development - Chitosan microspheres potential carrier for drugs

Drug Development - Class-action suit filed over brain cancer drug

Drug Development - Collaboration to develop pegylated formulation of Zadaxin

Drug Development - Conditionally replicating adenoviruses with short hairpin RNAs silence genes

Drug Development - Endotoxin testing not needed for inhalation grade lactose

Drug Development - Han fangji extract inhibits granulocyte activity in rheumatoid arthritis

Drug Development - Hepatitis C virus NS3 protease inhibitors need select elements for efficacy

Drug Development - Isoflavone metabolite inhibits ERK-1 activity in vascular smooth muscle cells

Drug Resistance - Different mechanisms produce VX-950 and BILN 2061 resistance

Drug Resistance - Short-term morphine exposure doesn't subdue multidrug resistance

Drug Resistance - Topoisomerase II alpha foils the effectiveness of etoposide in myeloma cells

Drug Resistance - c-Jun NH₂ -terminal kinase opposes prostate cancer apoptosis

Drug Safety - Study will use bioinformatics to examine genetic causes of adverse drug reactions

Eating Disorders - New instrument helps detect risk factors in Mexican women

Eating Disorders - Survey of cheerleaders suggests this may be an at-risk group

Eczema - Current smallpox vaccine can be harmful to people with skin disorder

Electronic Medical Records - Grant will help implement electronic health records in family practice medicine

Emphysema - Pivotal trial initiated for new emphysema therapy

End-of-Life Care - Some hospice patients and families talk of hastening death

Endocrinology - Androgen insufficiency found in premenopausal women with sexual dysfunction

Endocrinology - Androgen levels in women continuously decline, but SHBG doesn't

Endocrinology - Androgens work through prohibitin to steer prostate cancer growth

Endocrinology - Breast cancer cell CD36 expression ebbs in response to estradiol

Endocrinology - Human glucose transporter-like protein-9 characterized

Endocrinology - Intestinal secretion regulation involving neurotransmitters reviewed

Endocrinology - Metabolic products measured by NMR analysis of one glucose derivative

Endocrinology - Noradrenaline and neuropeptide Y from hypothalamus high in diabetes

Endocrinology - Obese or diabetes single gene mutations induce hyperglycemia-hyperinsulinemia

Endocrinology - Researchers design potent retinoid X receptor alpha agonists

Endocrinology - Study looks at early menopause changes in E₂ , FSH by ethnicity, age

Endometrial Cancer - Doctors don't agree on diagnosis of uterine cancer

Endometrial Cancer - Prognostic indicators of hyperplasias analyzed in postmenopausal women

Endometrial Cancer - Recurrent disease with a molecular alteration may respond to targeted therapy

Endometriosis - Mouse model developed as tool for drug testing, gene target validation

Endoscopy - FUSION biliary duct accessories with IDE technology introduced

Environment & Health - Air pollution affects preterm delivery and intrauterine growth restriction

Environment & Health - Dioxin exposure during pregnancy impairs mammary gland differentiation

Environment & Health - Maternal exposure to environmental pollutants affects fetal development

Environmental Health - Immunologic effects of perinatal PCB, dioxin exposure persist into school age

Environmental Health - Insulin-like growth factor 1 increased in people exposed to pollutants

Environmental Risk - Bacteria level closes Huntington Beach

Environmental Toxins - Air pollution is serious cardiovascular risk

Environmental Toxins - CDC offers $1.5 million for thyroid study of downwinders

Enzymology - ELISA methods for enzymes in cancer tissues developed

Enzymology - Evans Blue acts as protein tyrosine phosphatase inhibitor

Enzymology - High-throughput screening detects heat-shock protein 90 ATPase inhibitors

Enzymology - Seprase encourages tumor and microvessel growth in breast cancer models

Epidemiology - Postmenopausal Health Disparities Study looks at alcohol consumption

Epidemiology - Study finds high rate of genetic mutation in Korean women with breast cancer

Epilepsy - Distribution agreement announced for epilepsy treatments

Erectile Dysfunction - Erectile dysfunction may portend cardiovascular problems

Esophageal Candidiasis - Anidulafungin NDA does not support labeling claim for esophageal candidiasis

Etiology - Maternal-fetal interactions, birth order impact risk factors for adult diabetes

Evolution Genetics - Mathematical model used to determine course of HIV infection

Ewing Sarcoma - Ewing sarcoma of bone metastasizes to the lung

Exercise - Mechanism of cardioprotection studied in ovariectomized rats

Expression Analysis - Mouse genome microarray launched

Facilities - New proteome research center opens in Dublin

Facilities - Yale-New Haven considers $350 million cancer center

Fatty Liver Disease - Nonalcoholic steatohepatitis histologically resembles alcoholic liver disease

Female Genital Mutilation - Burkina Faso: Circumcisers are operating on baby girls to evade law

Fertility - Positive phase II data reported on Cetrorelix

Fibromyalgia - Cognitive difficulties studied in patients with rheumatic disease and FMS

Fibrosis - Syndecan-2 regulates transforming growth factor-beta signaling

Finance - $3.7M Series B financing to advance development of total artificial heart

Finance - $3M private placement to fund Oxycyte blood substitute clinical trials

Finance - Bio-filtration company reports 158% increase in revenues

Finance - Biopharmaceutical company announces pricing of IPO

Finance - Biopharmaceutical company announces subsidiary's bridge debt financing

Finance - Biotech company announces pricing of initial public offering

Finance - Biotech company complete $4 million funding arrangement

Finance - Biotech company delisted by Nasdaq

Finance - Biotechnology company approved for American Stock Exchange listing

Finance - Device company announces pricing of public offering

Finance - Device company focused on obesity secures $12M

Finance - Device firm reports 8% decrease in sales

Finance - Diagnostic products firm announces $1M private placement

Finance - Endoscopic product manufacturer announces financial results

Finance - Information management company reports first quarter results

Finance - Japanese company receives $600,000 investment from two Far East distributors

Finance - Life sciences company delists from Berlin stock exchange

Finance - Medical device company announces fourth quarter results

Finance - Medical information company in danger of NASDAQ de-listing

Finance - NASDAQ biotechnology index adds new company

Finance - NCI $1.9M grant awarded for GeneXpert platform research

Finance - New biotech public offering

Finance - Ophthalmology company announces secondary offering

Finance - Pharmaceutical company completes first phase of investor conferences

Finance - Pharmaceutical firm announces $25M underwritten stock offering

Finance - Pharmaceutical firm raises $51M in series C financing

Finance - Pharmaceuticals announces initial public offering

Finance - Pharmacy benefit and health care company announces annual results

Finance - Psychiatric drug maker reports loss of $0.36 per share

Finance - Quality Systems reports profitable fourth quarter

Finance - Vista Medical announces completion of private placement

Fitness - Panel: Count footsteps and calories

Fitness - Study: Driving longer means larger waists

Fitness & Wellness - Baby boomers pushing sales of comfortable, speedy recumbent bikes

Fitness & Wellness - Chick-fil-A offers healthier alternative with fresh fruit cups

Fitness & Wellness - Driving longer means larger waistlines

Fitness & Wellness - PETA launches child-friendly campaign in land of fried chicken

Food-Based Disease - United Nation's agencies call food safety a risk in Asia and the Pacific

Fungal Infection - FDA clears new fungal infection diagnostic test

Gastric Bypass - Seventeen chosen so far for $1 million gastric bypass experiment

Gastric Cancer -  Helicobacter pylori is associated with gastric cancer

Gastric Cancer - Results of phase II study of G17DT vaccine reported

Gastroenteritis - Efficacy results announced for gastroenteritis-causing rotavirus vaccine

Gastroenteritis - Licensing agreement will further research into norovirus treatments

Gastroenteritis - New license agreement for norovirus detection technology

Gastroenterology - ABCG2 may be involved in the evolution of colon cancer drug resistance

Gastroenterology - Etodolac staunches colitis-induced tumors in rodent models

Gastroenterology - Promising therapies available for the treatment of Crohn disease

Gastrointestinal Disease - FDA approves gastrointestinal selective antibiotic

Gene Delivery - Novel imaging assesses non-viral transfer systems

Gene Expression - Junk DNA yields new kind of gene

Gene Induction - Inducible promoters aid gene expression in head and neck cancer cells

Gene Silencing - Epigenetics may offer new approach to aging, cancer

Gene Transfer - 2-Amine is major bystander metabolite when CB 1954 is activated by NTR in tumors

Gene Transfer - High-capacity hybrid viral vectors garner transduction stability

Genetic Engineering - Stem cell factor gene-modified natural killer cells overwhelm tumor cells

Genital Herpes - Study shows herpes is common in U.S. suburban populations

Genomics - FBI awards contract for DNA analysis

Genomics - Gene encoding C. stercorarium beta-xylosidase Xyl43B in E. coli sequenced

Genomics - Genetic differences in ethnic groups affect the chronicity of hepatitis C

Genomics - Loss of heterozygosity on chromosome 12 concurs with lung cancer induction

Genomics - Premier issue of Zebrafish peer-reviewed journal launched

Genomics - RT(2) Real-Time PCR Gene Expression Assay Kits launched

Genomics - p16(INK4a) and p53 tumor suppressor genes altered in hTERT-immortalized cells

Genomics and Genetics - ChromoViz software graphically maps genomic data onto chromosomes

Genomics and Genetics - Estrogen-related genes identified in murine uterus

Geriatrics - Amide molecular clocks in Drosophila proteins may regulate aging

Geriatrics - Doctors offer their own health plan for seniors

Geriatrics - Dyspnea at rest may predict heart failure in older adults

Geriatrics - Nursing home residents spend most of their day bedridden

Ginkgo Biloba -  Ginkgo biloba protects liver against diabetes and hypoxia damage

Graves Ophthalmopathy - Role of cytokines in pathogenesis elucidated

Guillain-Barre Syndrome - Winston-Salem woman on the mend, after bout with rare nerve disorder

Gynecologic Surgery - Development of an adhesion-reducing substance would be helpful

Gynecologic Surgery - Postsurgical fibrosis regulated by programmed death-1 inhibitory pathway

Gynecology - Ovarian reserve tests might enable screening for early ovarian aging

Gynecology - Polycystic ovary follicular excess may be main culprit for follicular arrest

HIV Diagnosis - HIV-1/2 oral fluid rapid tests under development

HIV Prevention - CDC awards $49 million to support HIV efforts in communities across the U.S.

HIV/AIDS - (+)-Inophyllum B and (+)-calanolide A candidates for anti-HIV therapy

HIV/AIDS - AIDS-related NHL is treated traditionally as supportive care improves

HIV/AIDS - Argininamide binding arrests global motions in HIV-1 TAR RNA

HIV/AIDS - Ezrin/CD95 linkage key role regulating susceptibility to CD95-mediated apoptosis

HIV/AIDS - Intracellularly expressed HIV-1 Tat protein inhibits neural cell proliferation

HIV/AIDS - New protease inhibitors offer improved clinical effectiveness

HIV/AIDS - Pharmaceutical company launches second wave of Global Health Fellows Program

HIV/AIDS - Researchers explore gene treatment to make cells resistant to HIV infection

HIV/AIDS Gene Therapy - TAT-pK/DNA complex useful way to package therapeutic genes for cell transduction

HIV/AIDS Progression - Timed ablation of regulatory CD4+ T cells prevents AIDS progression

HIV/AIDS Research - Central domain of HIV-1 matrix protein influences virus infectivity

HIV/AIDS Research - Channels formed by Vpu result from the self-assembly of monomers

HIV/AIDS Research - FIV env-mediated fusion mechanism and kinetics are similar to HIV env

HIV/AIDS Research - Overexpression of Oct-1 or -2 has no effect on HIV-1 transcription in CD4 cells

HIV/AIDS Risk - One in three HIV-positive gay men unaware they are infected

HIV/AIDS Transmission - Improving perceived self-efficacy reduces HIV transmission behaviors

HIV/AIDS Treatment - Cell surface targets identified for HIV-1 therapeutics using genetic screens

HIV/AIDS Treatment - New protease inhibitors offer improved tolerability and safety

HIV/AIDS Treatment - State HIV funding in crisis

Haemophilus Vaccine -  Haemophilus influenzae meningitis in immunodeficient girl reported

Head & Neck Cancer - Docetaxel is active against squamous cell carcinoma of the head and neck

Head & Neck Reconstruction - Researchers use an innovative technique for cutting the pectoralis major muscle

Head and Neck Cancer - The loss of RASSF1A expression propels nasopharyngeal cancer proliferation

Health Education - Walgreens launches consumer health education program

Health Risk - Boy dies of blood infection; friends, relatives treated

Health Risk - Constitutional end sought to Adirondack water problems

Health Risk - Dogs are new tool in battle against mold

Health Risk - How to avoid mosquito bites and West Nile virus

Health Risk - Local governments hope to head off mosquito attacks

Health Risk - Nursing home reports three new Legionnaires disease cases

Health Risk - Pollutants drop 76% in bars and restaurants after smoking ban

Health Risk - Soap, insect nets over beds shown to be simple disease-fighting tools

Health and Fitness - Multiple myeloma patients commit to exercise based on a number of factors

Healthcare - WebMD Health launches Medicare Rx Benefits Resource Center

Healthcare & Politics - North Carolina senator raises concern over healthcare costs for state retirees

Healthcare Access - "VA-style' prescription drug benefit won't work in Medicare, pharmacy group says

Healthcare Access - Louisiana officials push for federal health clinics for uninsured

Healthcare Access - Significant increases in co-payments may reduce patients' use of needed drugs

Healthcare Benefits - Connecticut governor signs bill mandating wig coverage

Healthcare Costs - Controlling healthcare costs key to competitiveness, business leaders say

Healthcare Costs - Hospitals save $22M through supply chain improvement collaborative project

Healthcare Coverage - Arizona opts for self-insurance, starting this fall

Healthcare Coverage - Forum takes up interim Maine state health plan

Healthcare Coverage - Midwest bank and patient assistance program to offer loans for hospital bills

Healthcare Coverage - North Carolina Smart Start leaders rally at legislative building

Healthcare Coverage - Rhode Island's hospitals second least expensive in area

Healthcare Coverage - Texas CHIP program cuts outreach to families

Healthcare Demands - Official says baby boomers' health needs will hit hard in Indiana

Healthcare Funding - A look at proposed healthcare cuts for Louisiana in 2004-05

Healthcare Funding - Mexican tobacco companies to contribute $350 million to health system

Healthcare Funding - North Carolina repays $1.8 million in Medicaid overcharges

Healthcare Policy - A rise in hepatitis C-related diseases will impact managed care in the U.S.

Heart Attack - First international shipment made of automated external defibrillators

Heart Attack - The Methodist DeBakey Heart Center receives chest pain center accreditation

Heart Disease - Data demonstrate cardiovascular impact of weight loss with sibutramine

Heart Disease - Details of pacemaker study indicate efficacy of biomedical technology

Heart Disease - Enrollment in Taxus registry completed

Heart Disease - Mammograms may help predict cardiovascular disease?

Heart Disease - Positive results presented from PISCES stent trial

Heart Disease - StarClose vascular closure system launched

Heart Failure - AbioCor replacement heart implanted in 14th patient

Heart Failure - Anemia adversely affects outcome of diastolic heart failure patients

Heart Failure - B-type natriuretic peptide is useful in diagnosing heart failure

Heart Failure - B-type natriuretic peptide levels are associated with mitral regurgitation

Heart Failure - Illinois man is 10th in U.S. to survive for year or more with heart pump

Heart Failure - Mechanical support pumps can be a bridge to cardiac transplantation

Hematology - Age and packed cell transfusion volume act synergistically to increase mortality

Hematology - Bfl-1/A1 is a potent antiapoptotic stimulant in myeloma cells

Hematology - Cryoprecipitate-removed plasma is factor IX source for treatment of hemophilia B

Hematology - Updated results presented from phase III study of Dacogen in MDS

Hemophilia A - Linkage analysis and antigen assay detects 50% of carriers

Hepatitis - Hepatitis A virus cDNA-transfected Ltk-cells might reveal viral pathogenesis

Hepatitis - Hepatitis C virus NS3 and NS4A interactions modulate RNA unwinding activity

Hepatitis - New Phase II trial slated for chronic hepatitis C

Hepatitis A - Rates down dramatically among American Indians/Alaska Natives

Hepatitis A Vaccine - Benefits of hepatitis A vaccination for drug users investigated

Hepatitis A Vaccine - Immunogenicity data on Aventis Pasteur hepatitis A vaccines compiled