Health and Medicine Week

Acute Bipolar Mania - Risperdal reduces acute bipolar mania symptoms as early as day 3 of treatment

Allergy Medicine - National study shows 82% of U.S. homes have mouse allergens

Stem Cell Research - Stem cell transplants reactivate resolved hepatitis B virus infections

Vertebral Compression Fractures - Synthetic biomaterial restores function after vertebral compression fractures

Water-Borne Illness - Filtration protects patients from pathogens in hospital water

Abortion - Study compares data-collecting methods regarding attempted induced abortion

Accreditation - Bridgeport Hospital Chest Pain Center gets accreditation

Accreditation - Tennessee hospitals receive Chest Pain Center accreditation

Acquired and Inherited Diseases - Targeted Genetics signs exclusive license agreement with NIH

Acute Coronary Syndrome - Millennium, partner begin trial with INTEGRILIN (eptifibatide) Injection

Acute Lymphoblastic Leukemia - Family having hematopoietic cancers poses slight risk of offspring getting ALL

Acute myeloid leukemia - Fusion proteins overcome the hurdle of leukemia cell chemoresistance

Addiction Medicine - Liver function test results for naltrexone patients may be misleading

Addiction Medicine - Study finds greater severity in substance abuse in adolescent females

Adenovirus - Actin and its C-terminal peptide act as cofactors with adenovirus proteinase

Adipogenesis - Proteome analysis of adipogenesis conducted

Age-Related Macular Degeneration - SnET2 NDA accepted by FDA with priority review designation

Age-Related Macular Degeneration - Study will investigate safety, efficacy of PFTA as adjunct to Visudyne therapy

Allergy Medicine - Allergy vaccine disrupts structure of calcium-binding allergen

Allergy Medicine - Cytochrome P450 isoforms involved in oxatomide metabolism identified

Allergy Medicine - Lung proteome within airway mucosa following allergen challenge investigated

Allergy Medicine - Nanocrystalline silver cream potentially therapeutic for skin inflammations

Allergy Medicine - Total IgE measurement is valid surrogate for antigen-specific IgE

Alzheimer Disease - AApoAII amyloidosis induced by various heterogeneous amyloid fibrils

Alzheimer Disease - CD36 overexpression correlates with A-beta, not with Alzheimer disease

Alzheimer Disease - Infiltration of the brain by pathogens causes Alzheimer disease

Alzheimer Disease - Neurodegeneration and amyloid plaques occur in transgenic Drosophila

Alzheimer Disease - Olfactory dysfunction occurs in mice overexpressing human tau protein

Alzheimer Disease - Oxidative stress and mitotic changes necessary for Alzheimer disease progression

Alzheimer Disease - Reagan's death spurs renewed interest in AD, may lead to more donations

Alzheimer Disease - Scientist believes blood flow changes are key to understanding brain disease

Alzheimer Disease - Seeding specificity in amyloid growth induced by heterologous fibrils

Amyotrophic Lateral Sclerosis - Link suspected between soccer and amyotrophic lateral sclerosis

Anemia - Special protocol assessment agreed on for approval-enabling study of Ranexa

Angiographic Imaging - Study initiated for ferumoxytol under company's agreements with NCI

Angiology - Guidant to distribute technology designed to make heart bypass surgery easier

Angiology - Platelet-derived growth factor stimulates pericyte recruitment to tumors

Anthrax - CDC collaboration yields new test for anthrax

Anthrax - NIH supports phase I clinical trial of DNA-based anthrax vaccine

Anthrax - Public-private partnership extends Dutch-American cooperation in biodefense

Anthrax Vaccine -  B. anthracis antigens for testing anthrax immunity identified

Anti-Infectives - Antimicrobial drug development declining

Anti-Infectives - Thyroliberin controls murine candidosis

Antibiotics - Development and marketing agreement signed for novel formulation of amoxicillin

Antifungal Agents - New antifungal agents offer prospects for treatment

Apoptosis - PIDDosome activates caspase-2 in response to genotoxic stress

Arthritis Therapy - Short-stemmed modular shoulder prosthesis safe and effective

Artificial Heart - Diaphragm patch facilitates placement of AbioCor implantable replacement heart

Asthma - AT-101 device shows promising use for treating asthma

Asthma Epidemiology - Declining asthma rates in Mexico may indicate end of epidemic

Atrial Fibrillation - FDA issues non-approvable letter for Revelation Tx

Attention Deficit/Hyperactivity Disorder - Strattera provides full-day relief from ADHD symptoms in systematic study

Attention-Deficit Hyperactivity Disorder - Strattera now available in the United Kingdom

Autism - Maternal age and complications in pregnancy or birth may be risk factors

Autoimmune Disease - Link between vaccinations and autoimmune disease reviewed

Autoimmune Disease - MFG-E8 mediates removal of apoptotic germinal center B cells

Awards - Biotechnology company named on list of technology industry's top 100 companies

Awards - Doctor named young investigator of the year by gene therapy society

Awards - HIV/AIDS media campaign receives Peabody/Robert Wood Johnson Foundation Award

Awards - Memphis doctor wins cancer research award

B-Cell Lymphoma - c-FLIP mediates resistance of HRS cells to death receptor-induced apoptosis

Bacillus - Mosquito-larvicidal toxin produced by Bacillus sphaericus crystallized

Bacteria - Viral Antigens enters strategic collaboration

Bacteriology - ProSpecT EIA sensitive and specific for Shiga toxin I and 2 detection in stool

Bartonella - Diversity of Bartonella in rodents of Thailand determined

Behavior - Fights and vandalism shown to be related to drinking at school

Benign Prostatic Hyperplasia - Biotech firm submits response to FDA warning letter

Bile Duct Carcinoma - Retrograde portography shows important anatomy of the right caudate

Bioengineering - Can implants run on body heat?

Bioengineering - Collagenous matrices release exogenous growth factors for tissue regeneration

Bioengineering - Fluid dynamics research aids development of children's artificial heart

Biomedical Engineering - Human subjects play mind games

Biotechnology - Albumin-containing sol-gel glasses developed

Biotechnology - BioShield shortcomings subject of industry conference

Biotechnology - Experts warn that gene research could be used for warfare

Biotechnology - Four pH-dependent formation constants for free PSA elucidated

Biotechnology - Iowa governor says state is becoming a player in biotechnology

Bioterrorism - Defense Department starts first responder tech center at Pitt

Biowarfare - Vaccines for the prevention of diseases caused by potential bioweapons

Bipolar Disorder - Bipolar disorder study shows lack of treatment, frequent mistreatment

Bipolar Disorder - Seroquel combined with mood stabilizer may improve mania symptoms

Blood Glucose - Accuracy of blood glucose estimation by children with diabetes studied

Blood Glucose Monitoring - "All-in-one" blood glucose monitor and insulin pump receives FDA clearance

Blood Glucose Monitoring - TrueTrack Smart System receives FDA approval for alternate site testing

Blood Shortage - Annual summer blood shortage came early this year for Missouri

Blood Vessel - Company announces new intravenous gene-delivery method

Bone Repair - Calcium and thrombin trigger factors that spark endothelial cell proliferation

Bowel Incontinence - Secca clinical patient registry for bowel incontinence treatment

Brain Injury - Relation between stress and circulating levels of S100B protein reported

Brain Tumors - Diagnosis and treatment of brain tumors in children has improved

Brain Tumors - Microdissection-based genotyping aids reactive gliosis vs. glioma diagnosis

Breast Cancer - Active contour models help identify breast boundary in mammograms

Breast Cancer - Application filed for European marketing approval of RSR13 (efaproxiral)

Breast Cancer - Blood test detects genetic changes in progressive disease

Breast Cancer - Breast screening program in Australia detects more ductal carcinomas in situ

Breast Cancer - Combined mammography/MRI solution supports early detection of breast cancer

Breast Cancer - Complete nodal staging is beginning in men with breast cancer

Breast Cancer - ErbB3 is necessary for breast cancer proliferation

Breast Cancer - Follow-up data presented on autologous hemoderivative vaccine

Breast Cancer - Green tea may not decrease the risk of developing breast cancer

Breast Cancer - High mastectomy rates due to patients' choices, study finds

Breast Cancer - Increased access to high-quality mammography needed to reduce cancer deaths

Breast Cancer - Ipsilateral-mammogram computer-aided detection helps reduce false positives

Breast Cancer - MRI better than mammography for determining number, size of tumors

Breast Cancer - Nanoparticle form of paclitaxel is active in patients who failed taxane therapy

Breast Cancer - RARbeta P2 promoter methylation in RPFNA is biomarker for cancer risk

Breast Cancer - Researchers develop better understanding of tamoxifen resistance

Breast Cancer - Study casts doubt on Gail Model for predicting risk in African American women

Breast Cancer - Survivin, Bcl-2, p53 and bax expression increased in breast carcinoma

Breast Cancer - Vaccine containing multiple antigens generates higher immune response

Breast Cancer - Women treated for breast malignancies receive poor postoperative education

Breast Feeding - HealthPartners to study how to help mothers with decreased breast milk supply

Breast Implants - Article: Silicone implants not associated with connective tissue disease

Breastfeeding - FDA warns against women using domperidone to increase milk production

Budget Cuts - Some legislators upset two nurses not reinstated

Business Update - Biotechnology companies to co-develop DHA-rich safflower oil

Business Update - Bridge Pharmaceuticals Corporation launched

Business Update - Company acquires rights to novel proteasome inhibitors and related technology

Business Update - Company begins operation of 2500-liter bioreactor

Business Update - Company opens new preclinical pharmaceutical inhalation facility

Business Update - Company to acquire controlling interest in HBBenda

Business Update - Drug discovery company announces completion of two validation milestones

Business Update - HealthSouth reaches agreement with noteholders

Business Update - Hospira expands manufacturing capacity

Business Update - ImClone shares jump on favorable data on cancer drug

Business Update - Integrated BioPharma delivers update on paclitaxel API

Business Update - Legacy trauma center reopens

Business Update - MSSI-TeleScience receives $15M commitment

Business Update - Medical Media Systems changes name

Business Update - Mississippi hospital buys IV automation technology

Business Update - New HealthSouth CEO seeks to move firm past scandal

Business Update - Nutraceutical/pharmaceutical company selects Central American distributor

Business Update - Pharmaceutical firm announces move to new facility

Business Update - Pharmaceuticals firm acquires two new drugs for ADHD, completes financing

Business Update - Provider Synergies manages Medicaid pharmacy programs in Florida

Business Update - SEC finds Schering-Plough unit made bribes through charity

Business Update - Stem cell company announces plans for new facility

Business Update - Strategic Alliance formed for pulmonary delivery technologies

Business and Finance - Diagnostics company satisfies NASDAQ's initial listing requirements

Business and Finance - Psychiatric Solutions completes purchase of inpatient psychiatric facilities

Business and Finance - SunLink Health Systems completes sale of Mountainside Medical Center

Cachexia - Lipid-mobilizing factor protects tumor cells from oxidative damage

Caffeine - Mechanism of caffeine as psychomotor stimulant proposed

Cancer - Free electronic greeting cards offer encouragement to cancer patients

Cancer Biomarker - Epidermal growth factor receptor and Cerb-B2 fail to predict tongue cancer

Cancer Death Rates - Study finds rising death rates from prostate cancer after 15 years

Cancer Epidemiology - Annual report finds cancer incidence and death rates on the decline

Cancer Epidemiology - Men with vitamin D receptor polymorphisms are at risk for prostate cancer

Cancer Genomics and Genetics - Role of hMLH1 and HPP1 in adenocarcinomas determined

Cancer Prevention - Cancer risk lowered in those taking statins to prevent heart attacks

Cancer Prevention - More women opt for preventive surgery when they fully assess risks

Cancer Prevention - Warfarin does not prevent bladder cancer formation

Cancer Prognosis - Calcitonin gene hypermethylation marks the progress of leukemia

Cancer Risk - Cancer cause still a mystery in Vermont town

Cancer Risk - Illinois holding international conference on PCBs

Cancer Risk Factor - Familial tooth agenesis signals the risk for colorectal cancer

Cancer Risk Factor - Genetic shifts emerge during hepatitis C virus-linked carcinogenesis

Cancer Screening - U.S. National Cancer Institute in vitro drug screening has expanded

Cancer Suppression - Disrupted STAT3 signaling opens the door to tumor cell invasion

Cancer Surgery - Tumor cells can be removed from blood salvaged during cancer surgery

Cancer Therapy - ADVEXIN and INGN 241 featured at international scientific conference

Cancer Therapy - Alternating electric fields have potent antitumor activity

Cancer Therapy - Biomarker predicts response of colon cancer patients to chemotherapy regimen

Cancer Therapy - CMS and NCI collaborate to bring new drugs, better treatment to cancer patients

Cancer Therapy - Celecoxib is a potent chemopreventive agent

Cancer Therapy - Ceplene 36-month malignant melanoma survival data published

Cancer Therapy - Clinical safety, efficacy data of Advexin featured at scientific meeting

Cancer Therapy - Companies end Genasense expanded-access program in melanoma

Cancer Therapy - Drug treatment first big improvement in brain cancer in decades

Cancer Therapy - Endothelial cell-specific human antibodies might retard tumor growth

Cancer Therapy - Gene therapy tested to protect bone marrow during chemotherapy

Cancer Therapy - Hsp90 inhibitors enhance complement-induced tumor cell lysis

Cancer Therapy - Liver cancer expert presents new data on SIR-Spheres

Cancer Therapy - Loco-regional interferon after tumor irradiation regresses metastatic melanoma

Cancer Therapy - M2BP-derived CTL epitopes with possible use in cancer immunotherapy identified

Cancer Therapy - Medical product manufacturer to support CME program on RFA for cancerous tumors

Cancer Therapy - Near-infrared labeled endostatin localizes at tumors in animal models

Cancer Therapy - PTK/ZK completes enrollment for phase III metastatic colorectal cancer trial

Cancer Therapy - Patients' genes may influence how they experience fatigue and quality of life

Cancer Therapy - Phase I trial for anticancer compound Xl647 initiated

Cancer Therapy - Preclinical drug studies in rodents can predict phase I starting dose

Cancer Therapy - Researchers show potential of fighting angiogenesis

Cancer Therapy - Some drugs effective in rodent tumor models fail to perform clinically

Cancer Therapy - When combining new oral agents with standard chemotherapy, timing may be crucial

Cancer Threat - Study focusing on cancer link to creek in north Memphis

Cancer Treatment - Gene activity may change as breast cancer progresses

Cancer Treatment - Genetic differences explain severity of chemotherapy side effects

Cancer Treatment - Study shows virus can indicate cancer's aggressiveness

Cancer Vaccine - Antitumor immunity determined by the tumor not vaccine

Cancer Vaccine - B7-2 expression elicits anti-tumor immunity in B-cell lymphoma

Cancer vaccine - Cross-talk between dendritic and NK cells examined

Carcinogenesis - DNA methylation of integrin alpha 4 gene supports gastric cancer formation

Carcinoma - Bcl-2 expression decreases in endometrial carcinomas

Cardiac Arrest - FDA issues marketing clearance for AED Plus pediatric capability

Cardiac Monitoring - U.S. patent issued for methods and systems for processing ECGs

Cardiac Safety Monitoring - $1M study awarded for cardiac safety monitoring, information distribution

Cardiovascular Disease - Implantable defibrillator effective against hypertrophic cardiomyopathy

Cardiovascular Disease - Polyphenols in the diet may help prevent cardiovascular diseases

Cardiovascular Disease - The inflammatory response may be important in cardiovascular disease

Cardiovascular Disease - Urine albumin considered independent marker for kidney, cardiovascular disease

Cardiovascular Stents - U.S. patent issued relating to biocompatible HAp coating technology

Caregiving - Caring for breast cancer patients takes economic, emotional toll

Cell Biology - Bead-based assay is a poor model of apoptotic cell phagocytosis

Cell Biology - Researchers discover new way to identify cell growth

Cell Biology - Yale professor receives Johnson & Johnson Focused Giving award

Central Nervous System - Regulation of myelin proteolipid protein gene expression reviewed

Cervical Cancer - Genital HPV infections very low in northern Greece

Cervical Cancer - Human papilloma virus testing should precede cervical biopsy

Cervical Cancer - SOC1 inhibits HPV-E7-mediated transformation via degradation of E7 protein

Cervical Cancer - U.K. survey shows most people aren't aware of cancer/STD link

Cervical Cancer - Women having children by multiple partners have increased cancer risk

Charcot-Marie-Tooth Disease - New locus for Charcot-Marie-Tooth disease type 2 maps to chromosome 12q24

Chemical Danger - University study finds chemical not as harmful as state EPA says

Chemotherapy - Oral RDP58 permits CPT-11 dose escalation and relieves gastric tract toxicity

Childhood Obesity - Preschool policies and practices affect children's physical activity

Cholesterol - Reducol nears approval in New Zealand and Australia

Chronic Hepatitis C - Cellular compartmentalization is a trait of hepatitis C virus-host interactions

Chronic Liver Disease - A four-step model outlines the progress of non-alcoholic steatohepatitis

Chronic Obstructive Pulmonary Disease - Flu vaccine may prevent respiratory illness in patients with COPD

Clinical Studies - Company initiates Diquafosol phase III dry eye trial

Clinical Studies - Panel recommends CHARITE artificial disc for FDA approval

Clubfoot - Clubfoot with survival of motor neuron 1, telomeric gene deletion reported

Collaboration - Collaborative services agreement expanded by microarray company

Collaborations - AED distribution pact signed for People's Republic of China

Collaborations - Aegis enters into agreement with North Hills Hospital

Collaborations - Agreement signed for development of phase I HDAC inhibitor for cancer

Collaborations - Agreement signed to distribute BladderScan for urological diagnostics

Collaborations - Agreement signed with Althea Technologies for gene expression technology

Collaborations - American Healthways expands deal with Principal Financial Group

Collaborations - Biotech firms conclude agreement regarding manufacturing of cancer drug

Collaborations - Company begins exploratory collaboration with Novartis Institutes

Collaborations - Contract signed with Lockton Companies to control healthcare costs

Collaborations - Development of a Centocor therapeutic protein candidate advances

Collaborations - Distribution deal signed for Aeroneb Professional Nebulizer System

Collaborations - Dutch biopharma enters collaborative agreement with NMRC

Collaborations - Haemonetics extends partnership for body-warming systems in Japan

Collaborations - Iconix announces chemogenomics collaborative relationship

Collaborations - Joint marketing, assay validation agreement signed

Collaborations - Joint venture to target cardiac repair

Collaborations - License agreement completed for worldwide rights to hepatitis B product

Collaborations - Manufacturing, commercial rights to trandolapril acquired from Aventis

Collaborations - Middle East distribution deal signed for ActiPatch therapy

Collaborations - Sports medicine/exercise group joins Indiana's life sciences initiative

Collaborations - Systems biology company enters licensing agreement with Invitrogen Corp.

Colon Cancer - Eloxatin study demonstrates benefit over standard colon cancer therapy

Colon Cancer - Red meat ingestion is likely responsible for increased colon cancer in Japan

Colon Cancer - States awarded grant for colorectal cancer prevention educational program

Colorectal Cancer - Alternative genetic pathway to human colorectal cancer found

Colorectal Cancer - Assessment of lymph nodes in colorectal cancer specimens needs improvement

Colorectal Cancer - Avastin study shows extended survival in metastatic colorectal cancer patients

Colorectal Cancer - Cytochrome C depletion intensifies the immunogenicity of colon cancer cells

Complementary & Alternative Medicine - Salicin derivatives from H. cochinchinensis have antiviral activity

Complementary and Alternative Medicine - Lowly weeds may hold promise for curing host of common health woes

Complementary and Alternative Medicine - Many cancer patients turn to complementary therapies for healing

Constipation - SennaPrompt introduced for overnight relief of constipation

Contraception - Pregnancy more likely from one act of unprotected sex than previously believed

Cord Blood - Cancer research foundation offers advice on freezing and saving cord blood

Cord Blood Stem Cells - U.S. Patent Office requested to re-examine cord blood stem cell patent

Coronary Angioplasty - FDA does not approve application to amend existing Angiomax label

Coronary Artery Bypass Surgery - Fatal complications after symmetry aortic connector use described

Coronary Artery Bypass Surgery - Pre-op IgG therapy facilitates off-pump CABG in ITP patient

Coronary Artery Disease - Clinical trials of invasive coronary interventions have unanswered questions

Coronary Heart Disease - Cholesteryl ester transfer protein gene may protect elderly from heart disease

Coronary Heart Disease - Glucose-cholesterol may increase heart disease risk in hypertensive patients

Cosmeceutical Trends - Merging health and beauty trends drive cosmeceutical growth

Critical Care - Study examines deaths at pediatric ICUs

Critical Care Medicine - Detector-induced acute endotracheal tube occlusion reported

Critical Care Medicine - Management of postintubation stenoses in children reviewed

Crohn Disease - Diffuse alveolar hemorrhage reported after infliximab therapy

Cytomegalovirus - CMV viral load can guide clinical management of transplant recipients

Cytomegalovirus - Human cytomegalovirus large terminase subunit pUL56 characterized

DNA Damage - Attenuated p53 response in preneoplastic lesions growth advantage under stress

DNA Manufacturing - Company announces DNA fermentation breakthrough

DNA Repair - DNA double-strand break repaired by homologous recombination

DNA Research - Melatonin protects against oxidative stress in Chinese hamster B14 cells

DNA Research - XPC protein plays key role in cell cycle regulation during cisplatin treatment

Deep-Vein Thrombosis - Clot-busting drug-device combination provides effective treatment

Dementia - Prognosis estimations for advanced dementia patients

Dendrites - Dendritic guidance reviewed

Dengue Fever - IgG1 antibody for neutralization of dengue type 4 virus identified

Dengue Virus - Neugene antisense shows inhibition of tropical virus

Depression - School-based interpersonal psychotherapy effective for depressed adolescents

Depression - Study links chromium picolinate supplementation, reduced carbohydrate cravings

Depression - Study: Brain monitoring predicts treatment response in depressed patients

Diabetes - Pro-inflammatory cytokines not risk factors in older Korean women

Diabetes - Studies: Expanded population of stem cells successfully reverses diabetes

Diabetes Epidemiology - Prevalence of diabetes in the province of Girona, Spain reported

Diabetes Genomics and Genetics - IRS1 variant linked to type 1 diabetes in families from U.S. and U.K.

Diabetes Pathogenesis - Deficiencies in gut NK cell number and function precede diabetes onset

Diabetes Pathogenesis - Helper requirements for effector CTL to beta cell antigens outlined

Diabetes Pathogenesis - Insulin-like growth factors and pancreas beta cells reviewed

Diabetes Pathogenesis - Transcriptional networks controlling beta cell function identified

Diabetes Pathogenesis - pdx1 and HNF6 play roles in proliferation of endocrine precursors

Diabetes Therapy - Alliance to identify factors important to stem cell differentiation

Diabetes Therapy - Diabetes care and complications in remote health care setting described

Diabetes Therapy - Diabetes prevention using transgenic plants requires GAD and IL-4

Diabetes Therapy - Oral amino acids constitute metabolic therapy in patients with diabetes

Diabetes Therapy - Regenerated islets to be used to create supply for diabetes treatment

Diabetes Therapy - Sucanon marketing agreement signed for Mexico

Diabetes Therapy - Ticlopidine beneficial for hypercoagulability in diabetic patients

Diabetes Therapy - Treatment of type 1 diabetes by preserving insulin secretion reviewed

Diabetic Nephropathy - Glucose regulates glomerular endothelial cell proteoglycans

Diabetic Nephropathy - Streptozotocin injections cause early onset of glomerulosclerosis

Diagnostic Imaging - Multishot and single-shot fast spin echo sequences enhance tumor imaging

Diagnostics - A new quantitation assay details human papillomavirus load

Diagnostics - Breathalyzer offers new diabetes test potential

Diagnostics - Cedars-Sinai Medical Center to incorporate PNA FISH tests

Diagnostics - Collaboration to deliver 3D imaging applications for vascular X-ray systems

Diagnostics - Company receives orders for tuberculosis test kits

Diagnostics - ELISA for glial fibrillary acidic protein developed

Diagnostics - FDA approves Second Look 200 for breast-cancer detection

Diagnostics - FDA approves expanded labeling claims for SurePath Liquid-Based Pap Test

Diagnostics - Fixed-trypomastigote EIA may be a suitable candidate for blood bank screening

Diagnostics - Human urine contains colorectal cancer detection markers

Diagnostics - Intraoperative ultrasonography use is increasing in urologic oncology

Diagnostics - Novel immunoassay devised for HM-1 killer toxin measurement

Diagnostics - Pin1 may link signal transduction to cancer and Alzheimer disease

Diagnostics - Reactivity of yeast phase lysate Blastomyces antigens compared

Diagnostics - Synthetic peptide ELISA for rubella virus neutralizing antibodies effective

Diagnostics - Tag-It Mutation Detection Kits launched for P450-2C9 and P450-2C19 genes

Diagnostics - Zargis Acoustic Cardioscan cleared for marketing

Diet - LifeStyle Sensor Monitors to provide instant feedback on diet control

Diet and Nutrition - Effect of fiber types on digestibility of nutrients in cats reported

Diet and Nutrition - Food restriction reduces age-related sensitivity to oxidized lipids

Disease Management - New ways to deliver savings without compromising participant satisfaction

Disease Prevention - Connecticut receives $3 million for Lyme disease study

Disease Threat - Motel 6 denies hepatitis claim

Disease-Management Trends - Report explores adoption of pharma company's disease management programs

Drowning - PoolSafetyNetwork.org launched to help prevent drowning incidents

Drug Addiction - Probuphine effective in clinical trial as opiate addiction treatment

Drug Benefits - Employers adopting employee cost-shifting, wellness initiatives

Drug Benefits - Even among those who need them most, statin prescriptions go unfilled

Drug Compliance - Improving patient adherence integral to expanding antipsychotic market

Drug Delivery - Budesonide precipitation conditions affect aerodynamics

Drug Delivery - Carrageenan-based delivery of ophthalmic drugs shows promise

Drug Delivery - Degarelix-loaded PLGA microparticles may enhance prostate cancer treatment

Drug Delivery - Endothelial proteins accessible to drugs injected intravenously

Drug Delivery - Flow cytometry useful for measuring PLG microsphere protein loading

Drug Delivery - New polymer technologies introduced for site-specific drug delivery

Drug Delivery - Percutaneous intra-arterial catheter implantations transport liver cancer drugs

Drug Delivery - Researchers win Kaye prize for gastro-retentive sustained-release system

Drug Delivery - Uniform microspheres for drug delivery devised

Drug Development - Bispecific antibody shows promise as lymphoma therapy

Drug Development - Immunomodulatory activity of FIP-fve protein characterized

Drug Development - Immunomodulatory flavone glucosides isolated from Pleioblastus amarus

Drug Development - Immunomodulatory oxazolone derivatives synthesized

Drug Development - Multicellular tumor spheroids model HSVtk/ganciclovir systems in vitro

Drug Development - Puupehenone and associated compounds are angiogenesis inhibitors

Drug Development - Recombinant anti-MUC1 scFv has improved stability

Drug Discount Card - Blue Cross Blue Shield of Missouri offers drug card

Drug Discovery - FLIPR Tetra launched; offers 1536 kinetic measurements simultaneously

Drug Manufacturing - Pharmaceutical firm commences cGMP manufacturing of Thiovir

Drug Resistance - Bleomycin resistance stems from faulty transport mechanisms

Drug Resistance - Downregulated Bcl-2 or xIAP enhances the efficacy of breast cancer chemotherapy

Drug Resistance - Wild-type p53 polymorphisms anchor chemotherapeutic response

Eating Disorders - German version of the EDE is valid tool

Electronic Medical Records - Montrose Memorial Hospital selects PGP Universal to secure patient information

Emergency Medicine - University awarded patent for "date rape" drug test

Emergency Medicine - Women seem to tolerate traumatic injury better than men

Employee Health - Employers should provide wellness programs, according to survey respondents

Employee Health - ThedaCare, pharma, collaborate on employee health and productivity initiative

End-stage Liver Disease - De novo liver cancer in liver transplant candidates warrants list advancement

Endocrinology - Aldosterone signals modify bone marrow endothelial cell organization

Endocrinology - Hypothalamic glutamate decarboxylase expression cuts rodent feeding behavior

Endocrinology - Selenoprotein SelS is novel glucose-regulated protein

Endocrinology - Synthetic hormone in contraceptives, HRT causes negative effects in monkeys

Endocrinology - Vitamin D-mediated prostate cancer inhibition requires androgen signals

Endografts - FDA approves Zenith FLEX AAA endograft

Endometrial Cancer - Case report shows adenocarcinoma producing only free beta subunit of hCG

Endometrial Cancer - Clinicopathologic differences identified between EC and benign disease

Environmental Health - Dioxin-like compounds and endometriosis studied in Italian and Belgian women

Environmental Health - MS method to measure toxaphene congeners in human serum developed

Environmental Health - Novel assay provides rapid detection of 2,4-D and simazine pesticides

Environmental Toxins - Groups tout study showing lives lost to power plant pollution

Environmental Toxins - Lead levels not as safe as previously thought

Environmental Toxins - New ORNL project takes aim at heart of air quality, health issue

Environmental Toxins - Perchlorate may be acceptable in water at higher-than-recommended levels

Enzyme Stabilization - Water-based buffer for enzyme stabilization, storage available

Enzymology - Histone deacetylation is involved in ras-induced suppression of RECK

Enzymology - Nitric oxide is a negative regulator of endothelial cell migration

Epidermolysis Bullosa - Thymosin Beta 4 receives Orphan Drug designation for Epidermolysis Bullosa

Epilepsy - Anti-epilepsy drugs can increase rate of bone loss in older women

Epilepsy - Loss of circadian genes results in epilepsy

Epilepsy - Majority of epilepsy patients can work in competitive jobs

Epilepsy - Study confirms that Keppra provides opportunity for patients to be seizure free

Epilepsy - Transplanted stem cells do their job - new approach to epilepsy therapy

Erosive Esophagitis - Prevacid IV for Injection approved by the FDA for erosive esophagitis

Ethics - Age, race and sex disparity found in cancer research trial participation

Eye Cancer - New laboratory model can be used to test new treatments for pediatric eye cancer

Eye Health - Eye health information resource announced

Facilities - MaineGeneral board to build cancer center

Fertility - Autotransplantation of ovarian tissue recommended for trials only

Fertility - Oocyte cryopreservation gives cancer patients hope

Fibrinolysis - Plasma D-dimer identifies lymph node metastasis in breast cancer patients

Finance - $4.6M private placement completed for obesity disease management firm

Finance - American Stock Exchange lists common stock of islet transplantation firm

Finance - Antimicrobial-drug company announces exercise of over-allotment option

Finance - Assisted Living Concepts explores strategic financial alternatives

Finance - Cancer immunotherapies company announces closing of public offering

Finance - Cancer vaccine maker reports $1M net loss

Finance - Chinese biotech firm issues update on AMEX listing

Finance - Company focused on lipids announces sale of real estate assets totaling $5.4M

Finance - Device firm announces new financing

Finance - Diagnostics company files secondary registration statement

Finance - Disposables supplier reports record fourth quarter net income

Finance - Drug discovery firm completes series D financing

Finance - Eye-disease focused company completes secondary public offering

Finance - Fischer obtains $4.25M accelerated payment of remaining patent funds owed

Finance - HIV diagnostic test maker raises $9.3M in private placement

Finance - HealthExtras' executives adopt 10b5-1 plan

Finance - Increase in number of authorized shares of stock approved at pharmaceutical firm

Finance - MRI pharmaceuticals company prices $75M offering

Finance - Mark J. Gainor invests in medical device company

Finance - Med-Emerg commences closing of equity investment

Finance - Metropolitan Health files registration statement

Finance - Milestone payment issued from Amgen as part of drug R&D deal

Finance - Ophthalmics company's stockholders approve $16.5 million financing

Finance - Ophthalmology company increases stockholders' equity through debt reduction

Finance - Oral insulin developer retains financial advisory firm

Finance - Pain therapy device firm announces stock repurchase plan

Finance - Pharmaceutical R&D company completes $55M Series D financing

Finance - Pharmaceutical company reports loss of $0.69 per share

Finance - Transfusion company announces 3-for-2 stock split and stock repurchase program

First Aid - SEAL-ON launched; designed to stop bleeding fast

Fitness & Obesity - Pediatricians urged to advise patients on obesity

Fitness & Wellness - Fitness classes for babies may improve health

Fitness & Wellness - Greenville County, South Carolina, schools go healthier

Fitness & Wellness - Pregnant women now encouraged to stay fit

Fitness & Wellness - U.S. candy makers slim down their treats

Fitness & Wellness - Wellness program working at Southfield, Michigan, hospital

Food Safety - AccuPoint ATP sanitation monitoring system launched

Food-Borne Illness -  E. coli O157:H7 outbreak linked to salami in British Columbia

Food-Borne Illness - Bioassay suitable for screening of enrofloxacin residues in chicken

Food-Borne Illness - LC/MS analysis of brevetoxin metabolites in Eastern oyster reported

Food-Borne Illness - Plant pathologists present research on food safety

Fragile X Syndrome - FRAXA premutation correlated with premature ovarian failure

Fungal Infection - Voriconazole may prevent fungal relapse during at-risk periods of leukemia

Gastric Carcinoma - Histologically diverse lymph node lesions signal poor outcome in gastric cancer

Gastroenterology - Aurora-2 is a potential target for the treatment of pancreatic cancer

Gastroenterology - Clofazimine in lipiodol diminishes liver tumors in rodent cancer models

Gastroenterology - Diagnosis of gastroesophageal reflux disease reviewed

Gastroenterology Vaccine - Progress in enteric vaccine development outlined

Gastroesophageal Reflux Disease - Stretta procedure highly effective for GERD in obese patients, data shows

Gene Expression - Heterochromatin protein-1 affects dynamics of heterochromatin maintenance

Gene Therapy - New research on the progress of gene therapy presented at meeting

Gene Transfer - A new quantitative method measures the magnitude and volume of transgenes

Gene Transfer - NK4 transfection generates several modes of antitumor activity

Generic Drugs - Metronidazole Cream 0.75% introduced

Genetic Disorder - Aminoglycoside rescues disease-causing mutation in vasopressin receptor gene

Genetic Engineering - Administration route shapes the effects of IL-12-expressing dendritic cells

Genetic Engineering - Hematech develops way to use cow's blood to fight disease

Genetic Mutation - Germline mutations in Chernobyl cleanup workers' offspring are modest

Genetics - Company adds cell-based knockins to its vector application services

Genetics - Human Genome Project looks beyond man

Genital Herpes - Vaccine in final phase of testing

Genomics - Company announces genetic-detection advance in nature biotechnology

Genomics - FDA, NIH drive clinical genomics: Is widespread application in the near future?

Genomics - Pharmacogenomic profiling of PI3K/PTEN-AKT-mTOR pathway in tumors elucidated

Genomics - U.S., Australian researchers team to tackle marsupial mapping

Genomics and Genetics - 5' nuclease assay with minor groove binder probes effective

Genomics and Genetics - Cryptic 6q subtelomeric deletion characterized

Genomics and Genetics - Myc-associated zinc finger protein activates murine RAG-2 promoter

Genomics and Genetics - Stress-induced cellular gene expression characterized

Geriatrics - New research hints at genetic changes in brains that could explain aging

Geriatrics - Plasmid-based hormone therapy could improve disease or age-induced wasting

Global Health - Referral to district hospitals key to improving care for severely ill children

Growth-Hormone Deficiency - Companies agree to discontinue commercialization of Nutropin Depot

Guillain-Barre Syndrome - Mutations in CD14 or TLR4 not linked to GBS risk

Gynecology - Bikunin plus paclitaxel trims tumor burden and ascites in ovarian cancer models

HARS - Phase III trial to study Serostim as treatment, maintenance therapy for HARS

HIV & Cancer - EBV may play role in pathogenesis of head and neck cancers in HIV infection

HIV and Cancer - Prevalence of lung cancer increased in HIV-infected patients

HIV/AIDS - Co-administration of lopinavir decreases amprenavir concentration

HIV/AIDS - HIV-1 variant in patient with low viral load exhibits RNA dimerization defect

HIV/AIDS - Online health resource announces establishment of HIV Leadership Awards

HIV/AIDS - RNAi is gene-specific therapeutic option to control HIV-1 replication

HIV/AIDS Genetics - Multiple viral genes contribute to HIV-associated neuropathy

HIV/AIDS Genetics - Mutations at position 184 of HIV-1 RT affect virus titer and viral DNA synthesis

HIV/AIDS Genetics - Random genetic drift influences HIV-I env evolution during chronic infection

HIV/AIDS Pathogenesis - HIV-1 Vpr promotes ubiquitination and turnover of Vpr mutants

HIV/AIDS Prevention - Experts say AIDS prevention and treatment should be integrated to fight epidemic

HIV/AIDS Prevention - Misconceptions regarding condom use have implications for HIV prevention

HIV/AIDS Research - Atazanavir and tipranavir quantified in plasma by HPLC plus MS/MS

HIV/AIDS Research - CD4+ and CD8+ T-cell CDR3 clonotype expansion do not correlate with SIV viremia

HIV/AIDS Research - Conserved bulky hydrophobic residues help stabilize HIV gp120-gp41 complex

HIV/AIDS Research - Dendrites cross-present HIV antigens from live and apoptotic infected CD4+ cells

HIV/AIDS Research - Fas and FasL polymorphisms and haplotypes do not correlate with AIDS progression

HIV/AIDS Research - HIV-1 virions induce apoptosis through a CXCR4- or CCR5-dependent pathway

HIV/AIDS Research - Interaction between HIV-1 RT and dNTP substrate contributes to viral mutagenesis

HIV/AIDS Research - Major 5' site mutation renders CMV-driven HIV-1 proviral clone Tat-dependent

HIV/AIDS Research - SHIVKU-2 infects brain early after infection and persists until the AIDS stage

HIV/AIDS Research - Unusual ''senseless'' 2',5'-oligoribonucleotide has potent anti-HIV activity

HIV/AIDS Therapy - Research agreement renewed for development of novel HIV entry inhibitors

HIV/AIDS Therapy - Single-dose phase I trial of first-in-class HIV maturation inhibitor completed

HIV/AIDS Treatment - Alabama prison system settles suit as judge decries care of AIDS inmates

HIV/AIDS Treatment - Antiretroviral therapy adherence issues are elucidated

HIV/AIDS Treatment - Drug interactions occur between opioids and antiretroviral medications

HIV/AIDS Treatment - Drugs donated by AIDS patients in U.S.helps prolong lives worldwide

HIV/AIDS Treatment - G-8 adopts plan to speed HIV vaccine development

HIV/AIDS Treatment - Sociocultural barriers impede complementary and alternative medicine use for HIV

HIV/AIDS Treatment - Vif-resistant mutant APOBEC3G may provide gene therapy approach to HIV infection

HIV/AIDS Trends - Cases of HIV-infected newborns decline in New York

HIV/AIDS Virology - Virologic failure in HIV patients associated with poor adherence to NNRTIs

Head and Neck Cancer - STK15 polymorphism correlates with esophageal squamous cell cancer occurrence

Health - FDA certificate to export products to Japan granted for RespAide

Health Insurance - Benefits brokers see employer interest in HSAs growing

Health Risk - Teacher fired after student pricks finger on insulin needle

Healthcare & Politics - Missouri candidate says he opposes Medicaid cuts sought by House republicans

Healthcare Costs - HIRC's drug copay service shows trend toward increased patient cost-sharing

Healthcare Coverage - ACCC calls on CMS to allow for exceptions to ASP reimbursement

Healthcare Coverage - Detroit City Council OKs plan for a city-county health agency

Healthcare Coverage - Half of California voters support healthcare initiative

Healthcare Coverage - Health groups oppose a for-profit Premera

Healthcare Coverage - Humana introduces SmartAssurance, a consumer-engagement program

Healthcare Coverage - Humana introduces health offering that caps premium increases

Healthcare Coverage - Idaho's expanded children's health insurance plan approved

Healthcare Coverage - Making sure your health insurance company isn't curbing your medical treatment

Healthcare Coverage - Number of North Dakota residents without health insurance falls

Healthcare Coverage - State eliminates some co-pays in the Oregon Health Plan

Healthcare Coverage - Two companies to offer health insurance in South Dakota

Healthcare Financing - Growth in health care spending again drops

Healthcare Market - Survey reflects positive outlook for healthcare industry for remainder of 2004

Healthcare Workers - Deal reached with some New York City healthcare aides; others continue

Hearing Loss - Ceptor Corporation receives grant for hearing loss study

Heart Attack - Genetic markers linked to increased risk of heart attack

Heart Attack - River Park Hospital of Tennessee designated Accredited Chest Pain Center

Heart Disease Risk - Nitric oxide deficiency raises cardiovascular disease risk in African Americans

Heart Disease Risk Factor - Role of anchoring proteins in cardiac sudden death investigated

Heart Failure - Nuclear targeting may inhibit death of cardiomyocytes

Heart Failure - Oxidative stress may cause endothelial and myocyte dysfunction

Heart Failure - QMed provides heart failure management to Humana South Florida Medicare members

Heart Failure - Third heart sound can occur in patients with heart failure

Heart Failure - Ventricular assist can bridge heart failure patients until transplantation

Heart Surgery - Bivalirudin superior to heparin for thrombosis prevention

Heart Surgery - Expanded pouch enables safe intra-abdominal placement of Novacor device

Heart Surgery - Novel technique devised for pediatric mitral valve annuloplasty

Heart Surgery - Stenting can enhance treatment for cervical artery dissection

Heel Pain - Shockwave therapy offers non-invasive treatment for heel pain

Helicobacter -  H. pylori-specific antibodies counteract resistance against infection

Hematology - 1,8-Anilinonaphthalene sulfonate binds to central cavity of human hemoglobin

Hematology - Low-molecular-weight heparins may interfere with tumor growth and metastasis

Hematology - Split-signal FISH detect chromosome aberrations in acute lymphoblastic leukemia

Hemophilia - Foundation says it's not deterred by Avigen gene-transfer therapy announcement

Hemophilia - Immunosuppressive therapy can rapidly resolve acquired postpartum hemophilia

Hemorrhagic Fever - West Nile virus trial expands to include additional lethal viruses

Hepatitis B Virus - Low-level viremia of hepatitis B found in antibody-positive blood donor

Hepatitis C - Genetic vaccine promising against chronic hepatitis C

Hepatitis C Vaccine - Vaccine encoding hepatitis C antigens elicits specific immune response

Hepatitis D Virus - Hepatitis delta virus antigenomic RNA transcripts undergo alternate processing

Hepatocellular Carcinoma - Recent imaging techniques are helpful in detecting hepatocellular carcinoma

Hepatocellular Carcinoma - Selective resection margins attempt to contain liver cancer micrometastases

Hepatology - Cancer drugs and irradiation combine to overcome liver cancer proliferation

Hepatology - Expression of CYP3A4 mRNA correlates with metabolic activity in human liver

Hepatology - Forkhead box transcription factor is essential to liver cancer formation

Hereditary Angioedema - FDA permission granted to resume DX-88 clinical trials

Hip Replacement - Bone sialoprotein-coated femoral implants subject to loosening

Hip Replacement - Creep is main component of fatigue damage at cement-bone interface

Hip Replacement - Taper-design uncemented femoral stem may reduce bone loss

Hodgkin Disease - B7-2 protein levels reduced in HD tumor cells

Hodgkin Disease - Cigarette smoking is not associated with a risk of developing Hodgkin disease

Hormone Replacement Therapy - Long-term tibolone therapy appears to benefit lipid profile