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Sexual and Reproductive Health

Antibiotic-resistant strain of syphilis is spreading

Published in Health and Medicine Week, July 26th, 2004

A fast-spreading mutant strain of syphilis has proved resistant to the antibiotic pills that are offered to some patients as an alternative to painful penicillin shots.

Since the late 1990s, doctors and public health clinics have been giving azithromycin to some syphilis patients because the long-acting antibiotic pill was highly effective and easy to use. Four pills taken at once were usually enough to cure syphilis.

But now researchers at University of Washington in Seattle have found at least 10% of syphilis samples from patients at sexually transmitted disease clinics in 4 cities had a strain resistant to azithromycin.

"That...

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