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Health and Medicine Week

Susan Hasty, Publisher

Table of Contents . . . October 4th, 2004

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Health and Medicine Week | Other Publications

ADHD - Atomoxetine is novel treatment for attention deficit-hyperactivity disorder

Diabetic Neuropathy - Medical treatment of diabetic foot infections reviewed

Gastroesophageal Reflux Disease - New proton pump inhibitor formulation using IV esomeprazole developed

Obesity Risk Factor - Homeostatic and hedonic risk factors for overeating investigated

Obesity Surgery - Laparoscopic gastric bypass possible after failed open gastroplasty

West Nile Virus - West Nile virus and poliomyelitis reviewed

ADHD - 11.5% of Biodyne acquired by technology company

ADHD - DataLex ADHD Indicator Report assessment tool introduced

ADHD - FDA approves Methylin Chewable Tablets, Methylin Oral Solution for ADHD

AIDS/HIV Pathogenesis - AIDS progression linked to Fok-I polymorphism of VDR gene

AIDS/HIV Therapy - Memory CD4+ T cell responses in HIV not restored by antiretroviral therapy

AIDS/HIV Vaccine - Gag CTL-positive vaccinees recipients do not have anti-gag p17 response

AIDS/HIV Vaccine - HIV vaccine combination safe and immunogenic in HIV-negative adults

AIDS/HIV Vaccine - Heat shock protein mediates cross-presentation of exogenous HIV antigen

AIDS/HIV Vaccine - Immune responses to hemagglutinin/SHIV-like particle vaccine reported

AIDS/HIV Vaccine - Immunization with Listeria controls virus load after FIV challenge

AIDS/HIV Vaccine - Methods to monitor oligomeric state of HIV vaccine antigen evaluated

AIDS/HIV Vaccine - Papillomavirus-HIV-1 gp41 virus-like particles induce HIV antibodies

AIDS/HIV Vaccine - Plasmacytoid dendritic cell activation augments SIV-specific T cells

AIDS/HIV Vaccine - Recruiting London gay men into HIV vaccine trial is feasible

AIDS/HIV Vaccine - Screening for HIV-specific T-cell responses recommended

Acute Myeloid Leukemia - Chromosomal translocations involving 6p22 breakpoint identified

Addiction Medicine - Nicotine patches enhance effects of alcohol

Adenovirus - DNA binding to viral enzyme may serve as new target for antiviral drugs

Adhesions - Paper describes new treatment for prevention of postsurgical adhesions

Adolescent Health - Prevention programs need to address black female teens' wish to be pregnant

Adolescent Health - Study looks at family predictors of girls' sex-typed activities

Adverse Drug Effects - Calbindin-D-28K protects renal tubular cells from cyclosporine toxicity

Adverse Drug Effects - Sevoflurane exposure is associated with a case of infant hepatitis

Aging - Social and environmental factors play important role in how people age

Agricultural Biotechnology - Monsanto enters collaboration to develop nematode-resistant soybeans

Air Pollution - Neural models are better than statistical models in measuring pig farm odor

Air Pollution - Study says air worse in smoky bars than on truck-choked roads

Alcoholism - Sweet tooth, behavioral problems tied to alcoholism

Alcoholism - Youth drinking trends stabilize, consumption remains high

Allergies - Food Allergy Buddy dining card launched

Allergy - Drug in phase 2 clinical trial for patients suffering from peanut allergy

Allergy Medicine - DNA vaccine reverses allergic airway inflammation and eosinophilia

Allergy Medicine - Mom's atopic disease modifies effects of prenatal risk factors on exhaled NO

Allergy Medicine - Side effects greater with aqueous than depot therapy for bee venom allergy

Alzheimer Disease - Age-related myelin breakdown may be regionally heterogenous

Alzheimer Disease - Colostrinin found to be potential major advance in Alzheimer disease treatment

Alzheimer Disease - Cyclooxygenase-3 expression is ancillary to COX-mediated neuropathogenesis

Alzheimer Disease - Immunoglobulins might be promising treatment for AD

Alzheimer Disease - Mild AD leads to errors on driving test

Alzheimer Disease - Murine cerebral amyloidosis models exhibit impaired vascular formation

Alzheimer Disease - S- but not R-enantiomers of flurbiprofen and ibuprofen are neuroprotective

Amyotrophic Lateral Sclerosis - Spermidine and spermine levels higher in female ALS patients than males

Anesthesia - Hazards of surgery and anesthesia for drug, alcohol abusers presented at meeting

Anesthesiology - Novel airway approach algorithm developed

Anesthesiology - Patients with cardiac RyR defects had general anesthesia without complications

Anesthesiology - Phosphorylation alters Xenopus Ca-activated Cl currents

Angiology - Cellular mechanisms that control regulation of TASK-1 by PAF are examined

Angiology - Combination may provide a potential treatment of arterial thrombotic disorders

Angiology - Fluid shear stress induces endothelial KLF2 gene expression

Angiology - Glycoproteins have a procoagulant role in collagen-dependent thrombus formation

Angiology - New treatments may soon include agents known as the metabolic modulators

Angiology - Rac1 GTPase is a strategic target for tumor elimination

Angiology - Responses to BK of peripheral arteries and coronary arteries correlated

Angiology - Serial surveillance of patients is vital after arterial switch operation

Angiology - Slowed VO2 kinetics occur only with exercise of the affected limbs

Angiology - Vascular and valvular calcium levels linked

Angiology - aPT IgG is a significant marker for deep vein thrombosis/pulmonary embolism

Angiotensin - Gene-targeting experiments have elucidated AT1 receptor functions

Angiotensins - Chymase and carboxypeptidase A have key roles in generating and degrading Ang II

Animal Health - Request submitted to FDA for designated new animal drug listing

Animal Models - Animal models are guiding development of new immunotherapies for cancer

Anthrax -  Bacillus anthracis identified by multiprobe microarray hybridization

Anthrax Vaccine - In vitro-based potency assay for anthrax vaccine developed

Anti-Infectives - Combination of amphotericin B formulations improves efficacy

Anti-Infectives - Electrophoretic assay devised for fosfomycin determination

Antidepressants - FDA advisers want stronger suicide risk warnings about child antidepressants

Antifungal Drugs - Company updates the European development status of micafungin

Antifungal Therapy - Novel antifungal protein from gold kiwi fruit active against Fusarium oxysporum

Antihistamines - Two-thirds of prescription antihistamine users test negative for allergies

Antimicrobials - Ecopia selects four new compounds for further profiling

Antipsychotic Therapy - Study shows ACP-103 improves clinical profile of haloperidol treatment

Antiretroviral Therapy - Novel podophyllotoxin derivatives have anti-HIV activity

Antiretroviral Therapy - Recommendations made for two versus three drugs for postexposure HIV prophylaxis

Antitrypsin Deficiency - Alpha-1 gene therapy safely tested in first three patients

Antiviral Therapy - Multiferon is an alternative for treating difficult chronic hepatitis C cases

Aortic Regurgitation - Conservative surgery suggested when isolated lesion causes aortic regurgitation

Arrhythmia - Study addresses concern about association with ventricular tachyarrhythmias

Arthritis - Inhibition of nitric oxide synthase exacerbates GBS sepsis, arthritis in mice

Artificial Heart - Smaller driver for artificial heart licensed by cardiac device company

Assisted Reproduction - Laser-assisted ICSI reduces oocyte damage, pilot study shows

Assisted Reproduction - Patient drop-out rate is an indicator of an IVF program's quality

Assisted Reproduction - Study: Oocyte cryopreservation is a biologically "realistic objective"

Assisted Reproductive Technology - Sugar-coated sea urchin eggs could have sweet implications for human fertility

Asthma - Hand-held device measures airway inflammation

Asthma - IFN-gamma induces apoptosis in allergen-activated T cells

Asthma - Injected corticosteroids reduce eosinophilic airway inflammation

Asthma - Potential asthma monoclonal antibody to enter phase I clinical trial

Asthma - Regular sustained combination therapy may reduce asthma exacerbations

Asthma - Scientists discover link between serotonin and airway allergic inflammation

Astronomy - Scientists discover first Neptune-sized planets outside our solar system

At-Risk Populations - South Africa: Rural woman risk HIV for employment

Ataxia Telangiectasia - Plk1 loss from DNA damage independent of ataxia telangiectasia mutated kinase

Ataxia Telangiectasia - Understanding biology of AT can lead to greater knowledge of its underlying processes

Atherosclerosis - Antioxidant function of high-density lipoproteins in atherosclerosis reviewed

Atherosclerosis - Contributions of the A3 AR do not control vascular response to injury

Atherosclerosis - Improved understanding of atherogenesis has resulted in assessment techniques

Atherosclerosis - Paired iliac artery stent model helps determine drug-delivery device effect

Atherosclerosis - Vascular grafting is effective in revascularization

Atherosclerosis Vaccine - Anti-atherosclerosis polypeptide vaccine expressed in E. coli

Atherothrombosis - Inhibition of tissue factor can improve outcomes in atherothrombosis

Attention Deficit Hyperactivity Disorder - Study finds risk of ADHD greater in boys

Avian Influenza - Thailand decides not to allow vaccine use in poultry

Awards - Baby products manufacturer presented the consumers' choice award

Awards - Defibrillator manufacturer receives leadership award for product line

Awards - Gold award recipient for excellence in design of kidney transport system named

Awards - Journalist from Jordan wins Novo Nordisk Media Prize

Awards - Materials technologies specialist nominated for World Technology Award

Awards - Winners of European Respiratory Society 2004 awards 2004 from U.K. and Italy

Back Pain - Backpack safety starting to pay off

Bacterial Genomics -  Listeria monocytogenes composed of at least three evolutionary lineages

Bacterial Genomics - Multidrug-resistant S. enterica serovar Typhimurium found in shellfish in Spain

Bacterial Inhibition -  L. monocytogenes in biofilms controlled by competitive-exclusion microorganisms

Bacterial Resistance - Bacterial resistance increased from 1998 to 2002 in hospital in Slovakia

Bacterial Resistance - Community MSRA isolates in Australia belong to five CHEF electrophoretic patterns

Bacterial Resistance - MRSA strains susceptible to aminoglycosides genotyped

Bacterial Toxin - astA gene transposed into prophage of S. enterica serovar abortusovis

Bacteriology - Germ study suggests bloodletting may work

Bacteriology - Heat-shock proteins and host-pathogen interactions reviewed

Bariatric Surgery - Surgeons incorporate ON-Q PainBuster into outpatient bariatric surgical program

Batten Disease - Protein is key to fatal disorder and normal cell function

Behavior - Gambling linked to good health in elderly

Benign Prostatic Hyperplasia - Pharma company announces positive prostate drug trial results

Biochemistry - Oligonucleotide aggregation is important for toll-like receptor 9 activation

Bioengineering - Protein scaffolds guide capillary sprouting using an elastic fiber matrix

Biofilms - Multispecies biofilm communities in oral cavity influenced by coaggregations

Bioinformatics - Central composite design optimizes the formulation of LPD gene vectors

Bioinformatics - Experts develop new literature search engine for biologists

Biomechanics - Robot quantifies limb mechanics using estimates of dynamic end point stiffness

Biophysics - Biophysics institute receives grant for first U.S-based 4Pi Nanoscale Microscope

Biosynthesis - Researchers identify a cardiolipin-remodeling enzyme in the mouse

Biotechnology - Sol gel-based electrochromatography chip developed

Bioterrorism - Biopharm firm plans to develop radioprotective agents against nuclear terrorism

Bioterrorism - Connecticut to get $13 million to train for attack response

Bioterrorism - Study finds few health effects on dogs exposed to September 11 terrorist sites

Birth Defects - Brazilian mothers' beliefs about congenital abnormalities hold sway

Birth Defects - Fathers' occupational exposures may be linked to birth defects

Bladder Cancer - Comparative study released on superficial papillary urothelial carcinomas

Blood Donation - New York blood center sought donations during national preparedness month

Blood Glucose Control - Freestyle Mini, Precision Xceed blood glucose monitors launched in Europe

Blood Pressure Monitoring - ABP monitoring can ease obstacles of obtaining accurate BP in dialysis patients

Blood Substitute - Phase II clinical trial for Hemospan initiated

Blood/Marrow Transplantation - National Marrow Donor Program adds three new cord blood member banks

Bone Development - Novel periostin isoforms promote bone cell differentiation

Bone Grafting - Study shows clinical efficiency key to success of bone graft substitutes market

Bone Implant Model - beta-TCP is biocompatible in a weight-bearing sheep model

Bone Implants - New beta-type Ti-12Mo-5Ta alloy may be successful for biomedical applications

Botulinum Toxin - Profile of continuous antigenic regions of botulinum H-chain reported

Brain Cancer - Biologic therapy for brain cancers reviewed

Brain Cancer - Decoupling the control of brain cancer cells may lead to better treatments

Brain Cancer - European marketing authorization issued for expanded use of Gliadel Wafer

Brain Glioma - Orphan drug designation granted for Antineoplastons A10 and AS2-1

Breast Cancer - Autoantibodies to annexin XI-A, other autoantigens have biomarker potential

Breast Cancer - Bonefos accepted for filing and granted priority review by FDA

Breast Cancer - Brachytherapy applicator introduced for treating early-stage disease

Breast Cancer - Breast cancer-focused imaging company signs licensing, distribution agreement

Breast Cancer - Chemokines linked to breast tumorigenesis

Breast Cancer - Dense breast patterns evaluated with other risk factors of cancer

Breast Cancer - Hedgehog signaling pathway is new therapeutic target for breast cancer

Breast Cancer - IDSI adds VP to commercialize laser mammography in global markets

Breast Cancer - Mammaglobin-A vaccine has therapeutic potential

Breast Cancer - Meta-analysis supports IGF-I and IGFBP-3 level link with premenopausal cancer

Breast Cancer - New test discovers breast cancer at early, most treatable stage

Breast Cancer - Noninvasive breast fluid tests aim to detect disease at most treatable stage

Breast Cancer - Prolactin acts as a potent survival factor for human cell lines

Breast Cancer - RNA inhibition counteracts the growth of human mammary tumor xenografts

Breast Cancer - The cyclooxygenase-2 inhibitor SC-236 stops mammary tumor metastasis

Breast Cancer - U.S. FDA grants review of post-tamoxifen drug for early breast cancer

Breast Implants - Silicone induces strong local T-cell immune response

Bronchial Cancer - Intrapleural prosthesis resolves post-pneumonectomy pneumothorax

Burn Medicine - Neuromuscular pharmacodynamics of rocuronium determined

Business & Finance - Biopharmaceutical company receives $1.5 million from exercise of warrants

Business & Finance - Consumer products company confirms first quarter guidance

Business & Finance - Financial results, clinical pipeline update provide by pharma company

Business & Finance - Hemaseel maker provides Q3 update

Business & Finance - Home infusion therapy company provides 2004 financial results

Business & Finance - Medical technology company acquires assets of Coalescent Surgical

Business & Finance - Monitoring company announces stock repurchase

Business & Finance - Pharmaceutical company reiterates commitment to Mylan Laboratories transaction

Business & Finance - Pharmaceutical firm reports best year ever for sales, profits

Business & Finance - Venture capital company closes Inaugural fund under management

Business Trends - Forecast: Generic erosion may stunt growth of bipolar disorder drug market

Business Update - 2004 Employer and Coalition Service Profiles Supplement released

Business Update - Authority continues to seek Weston Hospital investors in West Virginia

Business Update - Celerity signs business development agreement with Getting Ready Corp.

Business Update - Centene launches CenCorp Health Solutions

Business Update - Clinical research organization implements quality management initiative

Business Update - Company announces US$24.4 million in sterols sales agreement

Business Update - Company focuses on regenerative medicine, sells blood conservation technology

Business Update - Denver Health settles with nurses, union

Business Update - Diagnostics company's CEO interviewed by wallstreetreporter.com

Business Update - ENT-103 maker provides progress report and litigation update

Business Update - Electrophysiology company enters relationship with Partners Equity Capital

Business Update - Endoscopy company comments on Israeli Health Ministry committee report

Business Update - Enterprise renames itself

Business Update - FDA completes inspection of stent-maker's Galway facility; no problems reported

Business Update - Financing for international distribution of Snorenz/SnoreAway announced

Business Update - Genomics company expands, relocates to new facility

Business Update - HealthTransaction Network announces network development/progress report

Business Update - Healthcare REIT closes new $300 million credit facility, declares dividend

Business Update - Healthlink opens U.K. office; National Health Service projects initial focus

Business Update - HearUSA realigns executive team to manage anticipated growth

Business Update - Hurricanes delay company's relocation plans

Business Update - ITT Industries to develop advanced imager for geostationary weather satellites

Business Update - ImpactRx selects wireless solution for data collection, transport needs

Business Update - Instrument maker announces new headquarters

Business Update - Ivy Tech, Indiana University to coordinate biotechnology programs

Business Update - Joslin affiliates with University of California, Irvine Medical Center

Business Update - Licensing agreement announced for hydrodynamic gene delivery technology

Business Update - MEDITECH and Zynx Health form strategic alliance

Business Update - MastaScope Mammary Ductoscopy System to be distributed in China

Business Update - Medical device company named to list of 100 fastest-growing companies

Business Update - Medical-technology company establishes U.S. operations

Business Update - Merit Medical Systems signs supplier agreement with Premier

Business Update - NHS Direct selects Bowne Global Solutions for interpretation services

Business Update - Nebraska Governor announces program for Hastings Regional Center

Business Update - Neighborhood Health Partnership selects ENS for E-Commerce services

Business Update - NitroMed up; to present trial data at conference

Business Update - Nonprofit hospitals alliance partners with Sinaiko Healthcare Consulting

Business Update - Nutritional supplements company reports a 34% increase in customers

Business Update - Operating income up at Fletcher Allen Healthcare in Vermont

Business Update - Partnership to promote R&D programs, technologies, products in Japan

Business Update - Pharma company unites divisions to become more R&D driven

Business Update - PillCam is the new brand name for video capsule product line

Business Update - Renaissance Medical Ventures formed to acquire distressed businesses

Business Update - Sonoma Health Care Center workers join union

Business Update - Surgery center owner expands with purchases in Ohio, Indiana and Louisiana

Business Update - VScan exposure increases in the Caribbean

Business Update - X-ray technology company announces productivity initiative

Calcium Channel Blockers - Different calcium channel blockers exert different effects on MMP-2 expression

Cancer Diagnostics - "Pill camera" to be developed to detect cancer, monitor body functions

Cancer Funding - MMA may result in 43%-54% loss in community-based cancer care funds in 2005

Cancer Research - PSA era is over for predicting prostate cancer risk, say Stanford researchers

Cancer Research - Phase I study of TNFerade for soft tissue sarcoma published

Cancer Screening - Tailored counseling may promote mammography among low-income rural black women

Cancer Suppression - Computationally predicted nucleotides halt bladder and breast cancer growth

Cancer Suppression - Lats2 boosts tumor apoptosis by down-regulating Bcl-2 and Bcl-x(L)

Cancer Therapy - Double drug combo attacks tumor and blood vessel development

Cancer Therapy - Gene therapy for bladder cancer shows strong results in animal studies

Cancer Therapy - Novel tumor antigen may be useful in osteosarcoma immunotherapy

Cancer Therapy - Peloruside A tubulin binding characterized

Cancer Therapy - Pharma company finds anticancer drug effective in reducing tumor size

Cancer Therapy - Radiation therapy center operator announces financing deal

Cancer Therapy - Radiation therapy management company expands into New Jersey

Cancer Therapy - Successful pre-IND meeting for AVR118 with FDA reported

Cancer Treatment - Afraid that cancer will return, doctors treat "cure" like a four-letter word

Cancer Vaccine - Antibodies in tumor immunotherapy reviewed

Cancer Vaccine - Dendritic cell-based immunotherapy for cancer reviewed

Cancer Vaccine - Gene-engineered T cells are superior adjuvant therapy for cancer

Cancer Vaccine - Heat shock proteins reviewed

Cancer Vaccine - Strategies to improve dendritic cell cancer immunotherapy outlined

Cancer Vaccine - Ubiquitin-fusion degradation pathway plays key role in DNA vaccination

Cancer Vaccine - Yeast-based immunotherapy causes mutation-selective tumor remission

Candidiasis -  Lactobacillus acidophilus-containing yogurt doesn't stop fungal infection

Candidiasis - Enrollment in phase 3 trial of anidulafungin for invasive candidiasis complete

Carcinogenesis - COUP-TFII encourages lung cancer cell invasion

Carcinogenesis - DMBA-induced mammary tumor progression depends on VEGF-dependent angiogenesis

Carcinogenesis - Defective gene thwarts cell talk, leading to breast and ovarian cancers

Carcinoma - Stromal bradykinin B-2 receptor signals foster tumor growth and angiogenesis

Cardiac Aging - Supplemental carnitine and lipoic acid improve the glutathione redox system

Cardiac Arrest - Cardiovascular drug cuts sudden cardiac death by 21%

Cardiac Arrest - Efficacy of biphasic defibrillators compared

Cardiac Arrest - Training key to defibrillator success

Cardiac Arrest - Where are we going with community defibrillation?

Cardiac Development - NT-3 may be important for cardiac development

Cardiac Function - Maintaining baroreflex function during 6 months of CyA treatment may be pivotal

Cardiac Hypertrophy - A3243G mtDNA mutation is linked to abnormal heart energetics and cardiomyopathy

Cardiac Side Effects - Alemtuzumab may have a role in inducing important cardiac side effects

Cardiac Surgery - Authors review cases of cardiothoracic surgery performed on Jehovah's Witnesses

Cardiac Surgery - Midazolam was a more effective antiemetic than ondansetron

Cardiology - Angiogenesis fosters the formation of aortic valve stenosis

Cardiology - C-reactive protein raises heart disease risk by impairing angiogenic function

Cardiology - Cannabinoid depresses respiration and enhances sympathetic tone and vagal tone

Cardiology - Cx43 and Cx45 connexins form diverse channels

Cardiology - Echocardiography is key to discussing indications for and timing of surgery

Cardiology - Effects of chronic hypoxia are described

Cardiology - Lysophosphatidic acid stimulates the adventitia to produce adrenomedullin

Cardiology - Mild exercise training does not increase MCT4; causes complex changes in MCT1

Cardiology - No evidence reported for phospholipase D activation by GI or IPC

Cardiology - Troponin sense and antisense interactions form the basis for a new hybrid RNA

Cardioprotection - Epo has untapped potential in cardiac treatment

Cardioprotection - Statins mobilize endothelial progenitor cells to improve cardiac function

Cardiotoxicity - Carbon monoxide may have two independent cardiotoxic effects

Cardiovascular Calcification - Calcium-free products bind phosphate without cardiovascular calcification

Cardiovascular Care - Cardiac rehab keeps heart patients fit, healthy

Cardiovascular Development - Endoglin plays a key role in cardiovascular development and vascular remodeling

Cardiovascular Devices - Radiological peritoneovenous shunt insertion feasible for intractable ascites

Cardiovascular Disease - Animal health company launches trials on dogs with heart diseases

Cardiovascular Disease - Giant coronary artery aneurysm rupture due to Kawasaki disease reported

Cardiovascular Disease - Par Pharmaceutical enters marketing agreement to its nitroglycerin lingual spray

Cardiovascular Disease - Treatment of intrastent restenosis reviewed

Cardiovascular Health - CV capacity, quadriceps muscle strength play modest role in rapid walking

Cardiovascular Health - Hemostatic factors did not correlate with functional TAFI levels in plasma

Cardiovascular Modulation - Medial prefrontal cortex has excitatory action on the sympathetic nervous system

Cardiovascular Stents - HAp stent coating successfully completes safety studies

Celiac Disease - Reproductive disorders associated with celiac disease in Brazilian patients

Cell Biology - Cell's gatekeeper for ammonia revealed in unprecedented detail

Cell Biology - New dye directly reveals activated proteins in living cells

Cell Biology - Novel myosin light chain kinase has unique structure

Cell Biology - Structure of clotting described in new study

Cell Biology - Targeted gene suppression delays senescence progression in human cells

Cell Development -  ZNF394 may play an important role in cardiac development, function

Cell Research -  Ligusticum chuanxiong and Angelica sinensis protect ECV304 cells

Cervical Cancer - Development of therapeutic nucleic acids is ongoing

Cervical Cancer - Interlaboratory results support Hybrid Capture 2 HPV test's reliability

Cervical Cancer - Mathematical model supports U.K. screening interval recommendations

Cervical Cancer - Non-European HPV type 16 variants more frequent in invasive disease

Cervical Cancer - Study reports "pronounced" chromosomal instability in advanced disease

Cervical Cancer - Upregulation of uPA by HER-2/neu appears to occur in early stage disease

Chemotherapy - Overexpressed dominant-negative FANCA helps cisplatin battle tumors

Chickenpox Vaccine - Rashes from Oka vaccine are derived from single clones of virus

Cholera - The flagellar motor controls exopolysaccharide expression in V. cholerae

Cholesterol Homeostasis - NPC1L1 may be useful for treating hypercholesterolemia and sitosterolemia

Cholesterol Research - Clinical benefit of statin-induced elevation of HDL-cholesterol is unclear

Chronic Fatigue Syndrome - Depression and CFS can be differentiated by psychophysiological measures

Chronic Hepatitis C Therapy - No patterns emerge with viral breakthrough during HCV combination therapy

Chronic Obstructive Pulmonary Disease - COPD patients prefer Respimat Soft MistTM Inhaler

Chronic Obstructive Pulmonary Disease - New research targets management of COPD

Chronic Obstructive Pulmonary Disease - Oxygen supplementation seems to be a promising treatment

Chronic Obstructive Pulmonary Disease - Spiriva reduces COPD exacerbations, related health resource burden, data shows

Claims Processing - Healthaxis and ppoONE formally announce expanded relationship

Claims Processing - Humana contracts with Availity

Cleft Palate - Researchers report new gene test for isolated cleft lip and palate

Clinical Trial - Study shows clinical trials last longer than expected

Clinical Trials - Clinical trials of drug for internal genital warts broadened

Clinical Trials - Companies initiate phase IIIb clinical trial of Tarceva in advanced NSCLC

Clinical Trials - Companies to commence second phase III trial for milnacipran in Q4

Clinical Trials - Diversa gets milestone payments for identifying protein therapeutic candidates

Clinical Trials - Patient enrollment begun for central precocious puberty phase 3 implant study

Clinical Trials - Phase 2 protocals submitted to U.S. FDA for clinical trials of synthetic blood

Clinical Trials Registry - Outline provided for developing national clinical trials registry

Clinical Trials Regulation - CRO group establishes global influence with Input to EMEA

Cognition - Nonword repetition tests the influence of genes or environment on learning

Collaboration - Alliance to discover, develop multiple small molecule oncology products

Collaboration - Financing agreement signed with HiProtech International

Collaboration - Strategic biopharm research, development and commercialization alliance formed

Collaborations - Additional drug discovery deal with Synaptic signed

Collaborations - American Healthways signs 3-year deal with Our Lady of Bellefonte Hospital

Collaborations - Blue Cross and Blue Shield of Illinois, Advocate extend relationship

Collaborations - Contractual agreement signed with Pfizer for cognitive tests

Collaborations - Development of new integrated PET/CT system reported

Collaborations - Diagnostics company enters broad diagnostic collaboration with Compugen

Collaborations - Distribution agreement signed for ReCell in Japan

Collaborations - Evotec enters agreement to help identify GPCR modulator-based new medicines

Collaborations - Pharmaceutical companies sign drug discovery deal

Collaborations - Pharmaceutical firm to license Accelrys software

Collaborations - Research agreement signed with Organon for assays

Collaborations - Supply agreement signed for needle-free vial adapter product

Collaborations - Update given on ICS technology development

Colon Cancer - Combination gene therapy reduces murine colon cancer cell growth

Colon Cancer - Positive results reported on colon cancer using its RECAF blood test

Colon Cancer - Strong association of ARK5 with tumor invasion and metastasis

Colon Cancer - Use of iron deficiency test as colorectal cancer screen feasible

Colonic Motility - Cocaine- and amphetamine-regulated transcript stimulates colonic motility

Colorectal Cancer - Colorectal neoplasm preoperative tattooing reliable for laparoscopic resection

Community Service - Search under way for tenth annual top youth volunteer awards

Complementary & Alternative Medicine - Kiwifruit and aspirin have similar effects for heart health, study shows

Complementary & Alternative Medicine - Oral surgeon warns: Herbals, surgery, and anesthesia don't always mix

Complementary & Alternative Medicine - PX3.102 appears to diminish chronic airway allograft rejection

Complementary & Alternative Medicine - Patient education about kava use in the perioperative period is suggested

Complementary and Alternative Medicine - Hibiscus flowers may prevent heart attacks

Complementary and Alternative Medicine - Screening test modified to identify herbals with sulfonylurea-like activity

Congenital Heart Block - Autopsy slides may provide clues to pathogenicity of maternal autoantibodies

Congenital Heart Disease - BNP concentration may be a useful tool in managing congenital heart disease

Congestive Heart Failure - CD4+ and CD8+ are altered in dogs with congestive heart failure

Congestive Heart Failure - Company reports oxypurinol clinical results

Congestive Heart Failure - Inhibition of aldosterone is warranted in congestive heart failure and hypertension

Congestive Heart Failure - Older women with heart disease, diabetes have triple the risk of heart failure

Congestive Heart Failure - Prolonged, sustained exercise prevents precursor to heart failure

Consumer-Driven Healthcare - Companies turn to CDHPs to curb double-digit annual cost increases

Continuing Medical Education - Continuing medical education program offered for hospitalists

Contraception - Antimicrobial peptide nisin is safe vaginal contraceptive agent

Contraception - Personal lubricant has antimicrobial and sperm-inhibiting potential

Coronary Artery Bypass - Bill Clinton treated at accredited chest pain center in New York

Coronary Artery Bypass - Interrupted distal anastomosis uses clips instead of sutures

Coronary Artery Bypass Grafting - Novel variation of radial artery described

Coronary Artery Disease - FDA approves small vessel cobalt chromium coronary stent

Coronary Artery Revascularization - Changes must be embraced for improved outcomes after coronary revascularization

Coronary Bypass - Statin therapy is beneficial to patients undergoing coronary revascularization

Coronary Lesions - FDA conditional approval granted to use Petal Stent System in BOSS trial

Coronary Syndrome - Two classes of indicators are under investigation

Coronary Syndromes - Knowledge of components of remodeling provide potential therapeutic targets

Critical Care Medicine - 3-D CT facilitates tracheal rupture diagnosis and treatment

Critical Care Medicine - Morbidity from repeated tracheal intubation characterized

Critical Limb Ischemia - Utility of excimer laser-assisted angioplasty reviewed

Crohn Disease - NOD2 is negative regulator of Toll-like receptor-mediated T helper responses

Cystic Fibrosis - Novel therapy has positive effect on lipid uptake in cystic fibrosis patients

Cytogenetics - Defective CD34+ progenitors compromise myelodysplastic syndrome therapy

DNA Research - Integrated electrophoretic chip devised for improved mutation detection

DNA Research - Microscopy method enables dye-free observation of lone DNA molecules

DNA Research - Novel electrophoresis chip provides fast, accurate biogenic amine analysis

DNA Research - Novel preconcentration technique devised for MCGE

DNA Research - Possible sources of microarray signal correlation bias identified

DNA Sequence - Life sciences company teams with Fisher to sell its services and products

Deafness - Non-European groups have a lower frequency of deafness related 35delG mutations

Death Discussions - Study found no regrets among parents who talked to their dying children about death

Degenerative Disc Disease - Intradiscal thermal annuloplasty effective for discogenic pain

Dendritic Cell Vaccine - Efficacy of dendritic cell-induced tolerance dependent on delivery path

Dengue Virus - RNA interference may protect humans from vector-borne infections

Dental Health - AARP offers dental insurance

Dental Health - Anthem Foundation of Ohio grants $1.1M for preventive oral healthcare

Dental Health - CDC guidelines help increase dental offices' cleanliness, safety

Dental Health - Dental plan urges patients to share medical history with dentist

Dental Health - Employee benefits provider announces arrangement with Dental Health Services

Dental Health - Oral surgeons explore anesthesia care for complex patients at conference

Dental Implants - Co-Cr/Ti dental implant couples may experience galvanic corrosion

Dental Procedures - OsSatura Dental receives 510(k) approval from U.S. FDA

Depression - Link between suicide, child sexual abuse may persist well into older adulthood

Depression - No racial disparity in depressive disorder seen in elderly home care patients

Depression - Panel urges child antidepressants warning

Dermatitis - Phase 2a trial results reported for investigational drug in atopic dermatitis

Dermatology - Light-based skin rejuvenation company signs agreement with Johnson & Johnson

Dermatology - Pharma company changes name of dermatology business to Intendis

Dermatology - Treatment of chronic venous leg ulcers trial results announced

Developmental Biology - Molecule awakens and maintains neural connections

Developmental Biology - New mechanism discovered in the regulation of mesenchymal-epithelial transitions

Developmental Biology - Researchers clarify mechanisms for beta-cell formation

Diabetes - Combination therapy of AVANDIA plus Metformin proven effective for diabetics

Diabetes - Diabetes treatment continues to show great promise; diabetes web site launches

Diabetes - Presentations of Exenatide show improvements in glucose control

Diabetes Genomics and Genetics - CYP27B1 polymorphisms variants linked to type 1 diabetes in Germans

Diabetes Management - Glucerna Crispy Snack Bars launch

Diabetes Pathogenesis - Absence of the reductase NCB50R causes insulin-deficient diabetes

Diabetes Surgery - Islet transplantation and regeneration for treatment of diabetes reviewed

Diabetes Surgery - Transplantation of pseudo-islets reverses hyperglycemia

Diabetes Therapy -  Withania coagulans extract has hypoglycemic activity in diabetic rats

Diabetes Therapy - Flavonol glycosides from Eucommia ulmoides inhibit glycation

Diabetes Therapy - LAF237 oral antidiabetic improves glycemic control in type 2 diabetes study

Diabetes Therapy - Sulfonylurea and phosphodiesterase inhibitors increase insulin secretion

Diabetes Therapy - Technosphere/Insulin therapy properties presented at international meeting

Diabetes Treatment - New dosages of Avandamet approved for type 2 diabetes

Diabetic Nephropathy - Adrenoceptor subtypes contribute to renal vasculature of diabetic rats

Diabetic Neuropathy - Diagnosing foot infection in diabetes reviewed

Diabetic Neuropathy - Methods for off-loading of plantar surface of the diabetic foot described

Diabetic Neuropathy - Multidisciplinary approach optimizes surgical therapy of diabetic feet

Diabetic Neuropathy - Overview of foot problems in diabetes presented

Diabetic Neuropathy - Quality of life with diabetic foot ulcerations worse than with amputation

Diabetic Neuropathy - Techniques for debriding and off-loading diabetic foot wounds described

Diabetic Neuropathy - Wound dressings for diabetic foot disease reviewed

Diabetic Retinopathy - Early treatment of diabetic macular edema may minimize vision loss

Diabetic Retinopathy - Subclinical inflammation supports the vasculopathy of diabetic eye disease

Diagnostics - BNP can be used to differentiate causes of respiratory distress in children

Diagnostics - Biologics company now manufacturing LiPro on a large scale

Diagnostics - Biotech holding company receives endorsement of Infectech's Identikit

Diagnostics - Direct protein microarray detection strategies reviewed

Diagnostics - ELVIS plate method is effective in detecting and typing herpes simplex

Diagnostics - Helicase-dependent isothermal DNA amplification offers portability advantages

Diagnostics - Minimal residual disease assessment predicts survival and relapse in AML

Diagnostics - Needle lung biopsy offers children less risk, less recovery time

Diagnostics - New factory opens in China to produce ultrasound scanners

Diagnostics - Platelet function can predict heart damage in acute MI patients, study shows

Diagnostics - Real-time polymerase chain reaction is more reliable for assessing ancient DNA

Diagnostics - Recommendations to optimize detection of host antibodies presented

Diagnostics - Specific patient circumstances should be considered prior to liver biopsy

Diagnostics - Vaginal, cervical cancer differentiated by cluster analysis of protein patterns

Diagnostics - Vessels surrounding gliomas respond to hypoxia with major changes

Dialysis - Time-integrated analysis should be used to examine all parameters concurrently

Diet & Nutrition - Eating fish helps slow atherosclerosis in women, especially those with diabetes

Diet & Nutrition - Plasma selenium decrease in pregnancy associated with glucose intolerance

Diet & Nutrition - Study: Optimal vitamin D-3 requirement probably much higher than RDA

Diet & Nutrition - Survey finds folic acid vitamin use by women at all-time high

Diet Trends - Discovery of multiple binding sites for sweeteners announced

Diet and Nutrition - Chronic stress promotes palatable feeding and reduces signs of stress

Diet and Nutrition - Mother's low-protein diet programs defective beta-cell function in offspring

Dietary Supplements - Rat study suggests L-leucine, taken orally during pregnancy, doesn't harm fetus

Disease Associations - Chlamydia trachomatis associated with invasive cervical cancer

Disease Management - Chronic pediatric illnesses not adequately addressed by current policies

Disease Prevention - Highmark partners with community groups, expands access to preventive healthcare

Disease Prevention - Zinc deficiency impairs immune function and resistance to infection

Disease Transmission - Lack of contraception in developing counties leaves women susceptible to HIV

Drug Addiction - Cocaine use increased dramatically in the United Kingdom from 1996 to 2002

Drug Addiction - Substance abuse programs would slow HCV transmissions among homeless men

Drug Claims - FDA warns Johnson & Johnson unit on pain patch claims

Drug Delivery - Heat-controlled drug implants offer hope for future

Drug Delivery - New gel pill could mean an end to injections

Drug Delivery - PLGA/mesoporous silica hybrid promising as drug release material

Drug Delivery - Short catheter, less invasive insulin pump infusion set released

Drug Delivery - Software company files Canadian patent application for talking pill bottle

Drug Delivery - Systemic gene delivery outpaces organ-directed delivery in rodent tests

Drug Delivery - Transdermal quercetin delivery not yet feasible

Drug Development -  Chlamys farreri polypeptide helps prevent UVA-induced skin damage

Drug Development - 3-FABS NMR provides reliable high-throughput functional screening

Drug Development - 96-well Caco-2 cell system facilitates P-gp screening

Drug Development - Aprotinin injection during artery bypass graft surgery may reduce risk of stroke

Drug Development - Arsenic trioxide inhibits hepatitis C virus replication

Drug Development - Biotech company picked to purify Philadelphia's infamous odor

Drug Development - Collaboration agreement signed for development of non-antibody protein

Drug Development - Companies initiate $26 million drug discovery collaboration

Drug Development - Computer model predicts CYP3A4 enzyme stability of drug candidates

Drug Development - Discovery of analgesic that increases potency of morphine announced

Drug Development - Drug companies are searching for new uses for existing drugs

Drug Development - Highly water-soluble microtubule modulator isolated

Drug Development - Hormonal cause of short stature linked to insulin-like primary IGFD, study shows

Drug Development - Japan-based chemical company to collaborate in R&D of antibactirial agent

Drug Development - Monoclonal antibody augments tallysomycin S-10b potency

Drug Development - Novel 14-helical beta-peptides are potent bilayer disrupting agents

Drug Development - Novel furamidine prodrugs have potent anti-trypanosomal activity

Drug Development - Personal protective lubricant for women cleared by U.S. FDA for marketing

Drug Development - Pharmaceutical company initiates phase 3 study for female arousal product

Drug Development - Pharmaceutical company validates oral hearing loss prevention drug

Drug Development - Plasmids produce insulin-like growth factor in transgenic rice and tobacco

Drug Development - Predictive Diagnostics partners to advance biomarker discovery

Drug Development - The fungal derivative RK-805 inhibits proangiogenic activity

Drug Development - Type 2 diabetes market to exceed $15 billion in 2013, study shows

Drug Discovery - Avestha Gengraine Technologies enters research agreement

Drug Discovery - Biosciences company and Roche choose to screen more G protein-coupled receptor

Drug Discovery - Partnership provides high-content screening technology to China

Drug Discovery - Roche and biotechnology company enter antiviral drug discovery partnership

Drug Discovery - Technology company announces revenues for fourth quarter

Drug Importation - Healthcare symposium addresses Canadian drugs

Drug Importation - Oak Creek, Wisconsin, mayor says he plans to veto Canadian drug proposal

Drug Importation - Wisconsin senators ask FDA why it intercepted drugs from Canada

Drug Manufacture - Leukocyte chromosomal DNA backs interferon production in Escherichia coli

Drug Monitoring - Column-switching LC-MS assay enables fast analysis of fluid samples

Drug Resistance -  Streptococcus pneumoniae emerging with very high resistance to penicillin

Drug Resistance - Antisense repression of p53 raises cancer cell chemosensitivity

Drug Resistance - Current epidemiological measures might not be sufficient to contain MDRTB

Dyslipidemia - Crestor reaches 10M prescription milestone

Earth Science - NSF awards $6.75 million to Caltech for geodynamics computational facility

Eating Disorders - EDI's psychometric properties valid in China

Echocardiography - Cornell criteria are best for males; Sokolow-Lyon criterion best for females

Ecogenotoxicology - Mini organ cultures of human epithelia can be used in ecogenotoxicology

Education - South African women using beaded crafts to talk about HIV/AIDS

Electronic Medical Record - Alliance partner to market Notes' HealthyPass portable EMR

Electronic Medical Records - Renaissance Health selects EMR solution

Electronic Medical Records - Technology company provides storm protection for medical information

Electronic Medical Records - User group meeting highlights electronic health record system success

Embryology - Retinol deficiency mars embryonic vessel growth by hindering angioblasts

Embryonic Stem Cell Research - Cultivation of fetal human hepatocytes attempted in microfluidic environment

Embryonic Stem Cell Research - Noncommitted neuroectodermal SCs integrate into brain during tissue genesis

Embryonic Stem Cell Research - Src family of tyrosine kinases important for embryonic stem cell self-renewal

Emphysema - Measuring quality of life for emphysema patients

Encephalitis Vaccine - Microparticle encephalitis vaccine elicits mixed immmune response

Encephalomyelitis - Chemokine receptor plays key role in pathogenesis of encephalomyelitis

Endocrinology - Cell-specific betaC-activin expression characterized

Endocrinology - MPA downregulates cytokine gene expression in mouse fibroblast cells

Endocrinology - Protein is key for digestive function of the pancreas

Endometriosis - Ectopic growths develop autonomic and sensory innervation in rat model

Endometriosis - IGF2 gene Apa I polymorphism not associated with endometriosis susceptibility

Enterovirus Infection - Enteroviral meningitis outbreak in France is caused by human echovirus 30

Enterovirus Infection - Enterovirus 71 strain causes neurological disease after oral infection

Environmental Health - Extraction method to measure halogenated compounds in breast milk developed

Environmental Health - Sensitive immunoassay for urinary permethrin developed

Environmental Health - Study predicts human damages from Indian Point nuclear plant terror attack

Environmental Health - U.N. organization warns that pesticide waste is time bomb in poor countries

Environmental Toxins - 9/11 search-and-rescue dogs exhibit few effects from exposure to disaster sites

Environmental Toxins - New statement published on nonmalignant diseases related to asbestos exposure

Environmental Toxins - September 11-related cancers may take years to become apparent

Epidemiology - Inhalation of particular matter can increase cardiovascular disease incidence

Epidemiology - Social variables not affected by increasing BMI in African American women

Epilepsy - Effects of vagus nerve stimulation determined in GAERS rats

Epilepsy - Positive trial results for epilepsy treatment reported

Epilepsy - Survey reveals impact of some epilepsy drugs on normal brain function

Epilepsy - Uridine release correlates with seizure activity

Evolutionary Biology - Enzyme contributed to enhanced brain function in apes, and ultimately, in humans

Evolutionary Biology - Human chromosome 5 final sequence analysis released to public

Exercise - AMP-activated protein kinase regulates glucose transport

Exercise - Biochemical basis of health effects of exercise reviewed

Exercise - Regulation of GLUT4 gene expression during exercise investigated

Eye Disorders - RetCam retinal imaging systems now operational in 32 countries

Eye Health - JECFA sets acceptable daily intake for lutein and zeaxanthin

Fabry Disease - Company successfully completes phase IV study of Fabrazyme

Facial Rejuvenation - Reloxin brand name announced for Botulinum Toxin Type A product

Facilities - California Pacific Medical Center opens Kanbar Cardiac Center

Facilities - Real estate investment trust to develop $33.2 million surgical hospital in Texas

Facilities - Study results reported on cath lab activity

Factor XII Deficiency - Mutation identified as molecular basis of congenital coagulation FXII deficiency

Fibromyalgia - Two serotonin receptor subunit genes cleared in FMS etiology

Finance - Acute care hospital firm offers senior subordinated notes, senior discount notes

Finance - Argatroban maker announces common stock offering of 4 million shares

Finance - Bioscience company raises $1.5M in Series A financing

Finance - Biosciences company announces third quarter financial results

Finance - Biotech company reports first quarter fiscal year 2005 financial results

Finance - Biotech firm's shares to trade on NASDAQ SmallCap market

Finance - British pharma firm closes GBP29M third round financing

Finance - Cancer therapy company unveils prime initiatives after major cash infusion

Finance - Cardiology device maker announces underwriters' exercise of optional shares

Finance - Company declares 372nd consecutive dividend

Finance - Cooper successfully sells $80M in bonds - its largest financing ever

Finance - Early-stage pharmaceutical announces $1M grant, 2 new hires

Finance - Financial holding company enters health savings account market

Finance - Friesland Bank obtains minority interest in Dutch company

Finance - Health Care REIT announces pricing of 7.625% cumulative preferred stock

Finance - Health Management Associates updates 2004 financial objectives

Finance - Health-products company announces repurchase program of its common stock

Finance - Healthcare corporation issues third quarter update

Finance - Hill-Rom parent announces fourth-quarter 2004 dividend

Finance - IMC Global files amended 10-K and 10-Q reports

Finance - Immune-focused company closes $6.4M in second round of private financing

Finance - Israel-based biopharmaceuticals company reports on 6 months ended June 30, 2004

Finance - Lab company announces 24% increase in quarterly net revenues

Finance - LanVision Systems reports second quarter financial results

Finance - Lancer Orthodontics announces financial year-end results

Finance - McKesson anticipates first half EPS between 75-80 cents

Finance - Mediware reports third consecutive year of record revenue

Finance - Memry Corporation reports 2004 fiscal year revenue of $34.5M

Finance - National HealthCare Corporation announces new independent accountants

Finance - Neurologix completes reverse stock split, changes ticker symbol

Finance - Oncology company to engage new independent audit firm

Finance - Pharmaceutical company closes on $30M Series B financing

Finance - Pharmaceutical company obtains an unsecured $100M credit facility

Finance - Pharmaceutical company raises $44M in Series C financing

Finance - Pharmaceutical company reports a 31% sales increase for the quarter

Finance - Pharmaceutical firm reports fourth quarter net income up 36%

Finance - Pharmaceutical firm secures seed funding of $1.6M

Finance - Prudential group reaffirms earnings per share guidance, focus on growth

Finance - Purified protein maker completes $2,535,000 private placement

Finance - RBX approved for reimbursement in China, eligible for grants

Finance - Royalty option exercised on Seasonale extended-cycle oral contraceptive

Finance - Surgical device company closes $12 million round of funding

Finance - Tissue Connect's parent discloses insider buying

Finance - Tissue engineering company completes $7.25M round led by Vitalife

Finance - Wellbutrin maker narrows revenue guidance

Fitness - Humana offers Medicare members free exercise and wellness programs

Fitness & Wellness - Arkansas governor urges businesses to encourage workers to exercise

Fitness & Wellness - Doctors suggest tax breaks for people who exercise

Fitness & Wellness - Encouraging kids to run marathons, a quarter-mile at a time

Fitness & Wellness - Family finds health, happiness on farm

Fitness & Wellness - Local leaders, national experts 'activated' to combat obesity, chronic diseases

Fitness & Wellness - Natural saline nasal wash released to help airline passengers fight cabin germs

Fitness & Wellness - Study urges inexperienced weightlifters to lift heavier amounts

Fitness & Wellness - The way to a more productive employee may be through the gym

Fluorescent Microscopy - Flash lamps suppress autofluorescence in water concentrates

Fontan Circulation - Patients with Fontan circulation have a progressive reduction of HRV over time

Food Poisoning - PCR identifies enterotoxigenic S. aureus strains from food poisoning outbreaks

Food Safety - Bioscience company supports national food safety education month

Foodborne Disease - Uncooked deer meat consumption presents a risk for hepatitis E virus infection

Galactose Assimilation - Pathways provide phenotypes useful in treating defects of galactose assimilation

Gangliosidosis - Excess GM1-ganglioside in brain cells triggers neurodegeneration, retardation

Gastric Cancer - Acidic polysaccharides may inhibit H. pylori adhesion to gastric cells

Gastroenterology - Novel animal model may improve study of H. pylori infection

Gastroenterology - Pediatric company acquires Protein Therapeutics

Gastroenterology - TGF-beta depends on glypican-1 for signaling in pancreatic cancer cells

Gastroenterology Vaccine - Centrally injected GLP-1 prevents some types of gastric mucosal damage

Gene Profiles - Androgen-responsive genes blanket the epididymis

Gene Promoters - Tumor-specific gene therapy targets uterine cervical cancer

Gene Transfer - VEGF receptor-1 mutant gene therapy curtails solid tumor growth

Genetic Disorders - Antisense therapy targeting GluR3 delays neurodegeneration in murine models

Genomics - A substantial genetic component to pulse pressure is identified

Genomics - Bioscience company launches IDSecure DNA identity service

Genomics - Biotechnology company and University extend tobacco genome initiative

Genomics - Loci differences influence susceptibility to angiogenesis-linked disease

Genomics - Lynx announces articles on gene expression technology

Genomics and Genetics - Efficient BAC transgenesis protocol developed

Genomics and Genetics - Novel system accurately predicts exon-skipping without ESTs

Genomics and Genetics - Utility of microarray analysis in vision research reviewed

Geriatric Testing - Group applauds House passage of memory screening proposal

Geriatrics - Drug compound thought to enhance brain functions to counter Alzheimer disease

Geriatrics - Prion protein may be involved in early-onset Alzheimer disease

Geriatrics - Silver Haired Legislature passes security, health dominant agenda

Geriatrics - Survey shows recreational gambling linked to good health in older Americans

Ginseng - Dendritic cell maturation drives Th1 polarization

Glaucoma - New approach to assessing glaucoma risk may help decide treatment needs

Glaucoma - Ophthalmology company presented at ophthalmic convention

Glioma - Activation of Akt and NFkappaB linked to diffuse tumor progression

Global Health - Harvard: World Health Organization strategy to control TB ineffective

Global Health - U.S. child health worse than other industrialized countries

Gynecologic Cancer - Gynecologic Cancer Foundation releases report on detection, treatment advances

Gynecological Oncology - Vascular endothelial growth factor-C associates with cervical cancer metastasis

Gynecology - Study validates kanamycin therapy for recently described aerobic vaginitis

Gynecology - Suicide gene therapy makes ovarian cancer susceptible to chemotherapy

HIPAA - Complicated regulations hinder basic science and clinical studies

HIPAA Compliance - Compliance 360 announces partnership with Strategic Management Systems

HIV/AIDS Coinfection - Antiretroviral therapy is safe for women with HCV infection

HIV/AIDS Epidemiology - Factors associated with short delay between initial HIV test and AIDS elucidated

HIV/AIDS Epidemiology - HIV testing rate among African Americans not increasing due to low awareness

HIV/AIDS Epidemiology - Indigenous foods help mitigate the HIV/AIDS crisis in West and Central Africa

HIV/AIDS Epidemiology - South African youth using safe-sex practices

HIV/AIDS Healthcare - HIV specialists and oncologists differ in pain management and palliative care

HIV/AIDS Healthcare - HIV-affected families must deal with complex psychosocial issues

HIV/AIDS Healthcare - Patient-provider relationship must improve to increase long-term quality of life

HIV/AIDS Infection - Normal CD4 and CD8 values established in healthy Chinese adults from Shanghai

HIV/AIDS Prevention - IVDA cessation concomitant with decrease in other addictions and unsafe sex

HIV/AIDS Research - Bivalent miniproteins enhanced anti-HIV activity over monovalent miniproteins

HIV/AIDS Research - HIV-1 nef effects on CD4 expression/infectivity are independent of rafts

HIV/AIDS Research - HIV-specific CTL cultures + IL-7 and IL-15 does not improve cell growth/function

HIV/AIDS Research - Ligands for ICOS potentially suppress HIV-1 replication mainly at entry stages

HIV/AIDS Research - Low-level HIV replication in glial cells associated with p55 alterations

HIV/AIDS Research - Polyanions are able to modulate HIV-1 pathogenesis

HIV/AIDS Research - Presence of functional vif influences HIV-1 infectivity and disease

HIV/AIDS Research - RT residue 215 active in resistance of multidrug-resistant HIV containing i69SS

HIV/AIDS Research - Simple model simulates cellular changes in T cells following HIV-1 infection

HIV/AIDS Research - Trim5 alpha protein restricts HIV-1 and murine leukemia virus

HIV/AIDS Research - Vif expression controlled to be low and optimal by proteasome degradation

HIV/AIDS Therapy - Efavirenz discontinuation associated with multiple factors

HIV/AIDS Therapy - Improved procedures produce good yields of HIV-1 integrase inhibitors

HIV/AIDS Therapy - Traditional healers vital in AIDS prevention and control programs in Africa

HIV/AIDS Treatment - Biopharm company announces start of clinical trial for HIV therapy

HIV/AIDS Treatment - First lady of Zambia dedicates new AIDS treatment clinic in Chikankata, Zambia

HIV/AIDS Treatment - WHO evaluates progress in providing AIDS drugs to victims in developing world

HIV/AIDS-Related Disorder - HIV-related sexual dysfunction in women mainly driven by psychological factors

HIV/AIDS-Related Infection - OI prophylaxis reduces drug-related toxicity and pharmaceutical interactions

HIV/AIDS-Related Neuropathy - gp120 and NRTIs cause sensory neuron apoptosis through activation of JNK pathway

Head and Neck Cancer - An excellent response to BNCT treatment seen

Head and Neck Cancer - Head and neck cancer brochure helps patients understand treatment

Head and Neck Cancer - Interstitial photodynamic therapy is effective for some head and neck cancer

Health Care - Financial rewards offered to Pennsylvania practices providing diabetes care

Health Care - LabOne signs national agreement to provide lab testing for Humana Inc.

Health Care - Medco's online pharmacy named best interactive web site for seniors

Health Care - Mountain States Health Alliance to install wireless infrastructure

Health Care - National opinion survey findings reported on Americans and health care reform

Health Savings Account - Federal employees' 2005 health benefits program adds HSA option

Healthcare & Politics - Oregon senator, wife honored for legislative role in youth suicide prevention

Healthcare & Politics - Senate candidate unveils healthcare plan to Charlotte, North Carolina, voters

Healthcare & Politics - Vermont gubernatorial candidate proposes universal health plan

Healthcare Access - Health Net transitions into TRICARE's northeast and national capital areas

Healthcare Access - New Mexico Governor wants more school-based clinics

Healthcare Costs - Study documents high markups on hospital charges

Healthcare Costs - Study shows cost considerations driving U.S. formulary and clinical guidelines

Healthcare Coverage - Alabama task force makes recommendations on curbing healthcare costs

Healthcare Coverage - E-Board asked to cover rising state health insurance costs

Healthcare Coverage - Employer-sponsored health insurance premiums increase 11.2% on average in 2004

Healthcare Coverage - Feds propose extension of miner health plan funding

Healthcare Coverage - Feds provide cash to help uninsured, underinsured in Idaho

Healthcare Coverage - Florida Governor announces changes in KidCare health insurance program

Healthcare Coverage - Former Canadian Prime Minister says universal healthcare works in Canada

Healthcare Coverage - Generation gap widened in social spending for elders compared to children

Healthcare Coverage - IPA SBRB study indicates healthcare as fastest growing small business cost

Healthcare Coverage - Insurance company announces execution of agreement to acquire HealthMarket, Inc.

Healthcare Coverage - Insurance department extends review and comment period on BCBS plans

Healthcare Coverage - Insurer managing healthcare for military families under DoD contract

Healthcare Coverage - Kentucky's Governor defends insurance plan before rowdy crowd

Healthcare Coverage - Language is top barrier for Hispanics to receiving medical care in the South

Healthcare Coverage - Majority of surveyed Americans consider health care costs "unreasonably high"

Healthcare Coverage - More Oregonians victims of health insurance fraud

Healthcare Coverage - New Hampshire Governor meets with Health and Human Services Secretary

Healthcare Coverage - New Health Plan NCQA Accreditation awarded to Unicare for Medicaid business

Healthcare Coverage - Oregon state worker benefit funding delayed

Healthcare Coverage - Poll finds 47% in New Mexico favor national health plan

Healthcare Coverage - Private health insurance premiums rose 11.2% in 2004, survey shows

Healthcare Coverage - Religious leaders want to discuss TennCare changes with Bredesen

Healthcare Coverage - Tennessee Governor gets support for TennCare reform from providers

Healthcare Coverage - Texas leaders call for elimination of teacher health reimbursement accounts

Healthcare Coverage - UMB Bank and prepaid card provider launch health savings account

Healthcare Coverage - Vermont Governor unveils healthcare package

Healthcare Coverage - Waiting list for cheap Pennsylvania-provided health insurance growing

Healthcare Coverage - Web-based software application provides certificates of insurance on demand

Healthcare Fraud - Burlington, Vermont, eye doctor charged with healthcare fraud

Healthcare Funding - Canada announces $31.6 billion, 10-year healthcare investment

Healthcare Funding - Clarksburg, West Virginia, hospital drops rate-setting appeal

Healthcare Funding - Five hospitals' rate increase requests reduced by Vermont officials

Healthcare Funding - Health agency officials discuss budget concerns with South Carolina Governor

Healthcare Funding - Ottawa rejects premiers' demand for $36.5 billion in new healthcare funding

Healthcare Funding - Prime Minister Paul Martin's healthcare gamble pays off, for now

Healthcare Funding - Virginia State Health Department gets $20 million

Heart Attack - Clinton was a "vulnerable patient"

Heart Disease - "Bill Clinton Effect" substantiated by bio-surveillance system

Heart Disease - Benefits of EECP therapy for heart disease presented

Heart Disease - Enrollment completed for trial studying unnecessary right ventricular pacing

Heart Failure - Expanded indication for cardiac resynchronization therapy defibrillators

Heart Failure - FDA approval sought for AbioCor replacement heart

Heart Failure - Myocytes with normal sinus rhythm were clearly differentiated

Heart Failure - SERCA2a restoration ignites transcriptional changes in the failing heart

Heart Rhythm - Power spectral analysis of heart rate variability is a useful method

Heart Surgery - Mended Heart's volunteers offer help to recovering heart surgery patients

Heart Transplantation - Thymic injection of anti-Fas mAb improves cardiac graft survival

Heart/Lung Function - Cardiovascular responses to hypergravity depend on the posture of the subject

Heat-Related Health Risks - Report says pattern of hotter days will cause more deaths in California

Helicobacter Heilmannii - MALT lymphoma occurs in an animal model of H. heilmannii infection

Hematology - Epigallocatechin-3-gallate interrupts leukemia cell survival signals

Hematology - Institutional transfusion programs have socioeconomic significance

Hematology - RHD 1227A is a genetic marker for people with the rare variant RhDel

Hematology - Thrombopoietin gene alterations may cause familial thrombocytosis

Hematopoiesis - GATA-1 controls neurokinin-B synthesis in erythroid cells

Hemochromatosis - Bilirubin may counteract the effect of oxidative stress from iron overload

Hepatic Resection - Bleeding avoided in hepatic resection with Tissuelink Monopolar Floating Ball

Hepatitis - Strategies to manage patients with viral hepatitis discussed at conference

Hepatitis A - Fully automated test for Hepatitis A virus released

Hepatitis B Vaccine - High-risk groups for hepatitis B need higher vaccine rates in France

Hepatitis C Virus - CCR5-Delta32 and CCR2-V641 polymorphisms not related to HCV infection response

Hepatitis C Virus - Cirrhosis and hepatocellular carcinoma increasing despite HCV infection decline

Hepatitis C Virus - Dosing complete in phase 1a study of oral HCV protease inhibitor for hepatitis C

Hepatitis C Virus - Reference laboratory network selects hepatitis C virus genotyping reagents

Hereditary Hemorrhagic Telangiectasia - Radiosurgery effective for cerebral arteriovenous malformations

Herpes Simplex Virus - IFN-gamma, TNF-alpha antiviral effects depend on indoleamine 2,3-dioxygenase

Herpesvirus - HVS Orf51 protein has role in viral pathogenicity/persistence/cell tropism

Herpesvirus - Post-transcriptional regulator of KSHV controls gene expression through IRES

Herpesvirus Vaccine - MAdCAM-1-expressing sacral lymph nodes provide site for immunity

Herpesviruses - Marijuana may be useful as an antiviral drug

Hip Replacement - Efficacy of total hip arthroplasty for hip osteonecrosis reviewed

Hookworm - Hookworm aspartic proteases reviewed

Human Behavior - The serotonin transporter gene does not link carbon dioxide to panic disorder

Human Immunodeficiency Virus - HIV-1 nef down-regulates antigen-presenting molecules

Human Papillomavirus Vaccine - HPV 16 L2E6E7 booster vaccine elicits immune response

Human Papillomavirus Vaccine - HPV type 16 L1 virus-like particle vaccine may prevent infection

Hypercholesterolemia - Data supports Fluvastatin's renal safety profile in high-risk patient population

Hypercholesterolemia - Rosuvastatin lowers asymmetric dimethylarginine in hypercholesterolemia

Hypertension - AT2 receptor results in lower blood pressures

Hypertension - Baseline and approaches to data analysis of hypertension trial presented

Hypertension - Clinical study to evaluate HCT 3012 effects on blood pressure initiated

Hypertension - Company announces priority review designation for Ventavis NDA

Hypertension - Control of extracellular volume and sodium normalize BP in dialysis patients

Hypertension - Effects of CYP11B2 and AT1R on heart rate depend on sodium excretion

Hypertension - Interventions to curb CV mortality of ESRD should target hypertension and LVH

Hypertension - Intravenously and subcutaneously administered treprostinil are bioequivalent

Hypertension - Notice of allowance received for synthetic, nonpsychotropic cannabinoids

Hypertension - Nutritional antioxidants have beneficial effects in stroke-prone rats

Hypertension - Perinatal factors could program an individual for risk of cardiovascular disease

Hypertension - Physicians want methods to integrate hypertension trial results into practice

Hypertension - Prolonged and frequent dialysis permits better control of hypertension

Hypertension - Researchers find new yogurt lowers high blood pressure

Hypertension - The renal medulla plays a pivotal role in long-term regulation of blood pressure

Hypertension - Transgenic models give a better understanding of the renin-angiotensin system

Hypertrophic Obstructive Cardiomyopathy - Left ventricular apex epicardial pacing can be effective for HOCM patients

Hypoxia - Enhanced fatty acid metabolism may spare carbohydrate for fuel in hypoxia

Hypoxia - Small molecule inhibitors counteract hypoxia-inducible transcription in tumors

Hypoxic Apnea - Thermal stress prevents autoresuscitation from hypoxic apnea

Imaging - Company introduces new Micro CT System

Imaging - Digital imaging company signs supplier agreement with U.S. Veterans Affairs

Imaging - Increased use of CT in past decade results in decreased costs for hospitals

Imaging - Molecular imaging annual meeting highlights ability to view disease in vivo

Imaging - Molecular imaging solutions demonstrated at conference

Imaging - Researchers develop assay for tracking internalization

Imaging - Systolic mitral annulus velocity not a reliable index of contractile performance

Imaging - Technique replaces intra-arterial digital subtraction angiography

Immunizations - Domestic violence threatens health of children with lower immunization rates

Immunizations - Parental vaccination beliefs in inner-city population described

Immunodeficiency - Jak3 evaluations will shed new light on human immune system disorders

Immunology - CCL2 underlies heightened infection risk in SIRS mice

Immunology - Fungerin arrests cell cycle by inhibiting microtubule polymerization

Immunology - Gamma-delta T cells expressing chimeric receptors offer antitumor control

Immunology - SLAM-SH2D1A plays role in regulation of T-dependent humoral immune responses

Immunology - Scientists explore biologicals as new approach for inflammatory diseases

Immunology - Small bowel intraepithelial lymphocytes isolated using magnetic beads

Immunology - TGF-beta1 may be involved in the pathogenesis of chronic liver disease

Immunology - TNF alpha-competing peptide mediates dendritic cell transfection

Immunosuppressive Therapy - Antisense approach to transplant acceptance works by regulating lymphocytes

Immunotherapy - Multikine immunotherapy drug lowers cholesterol in cancer study patients

Infant Mortality - Report says Alabama infant mortality at all-time low

Infectious Disease -  Giardia lamblia funis visualized

Infectious Disease - Immune responses suppress CMV reactivation in presence of pathogenic bacteria

Infectious Disease - NIH biodefense contract aims to unlock proteomes of salmonella, pox

Infectious Disease - Shiga toxin 1-neutralizing Fab fragment isolated

Inflammation - Markers of habitual inflammatory status in overweight women compared

Inflammatory Bowel Disease - Bacteria may be at root of Crohn disease

Inflammatory Bowel Disease - Genetically modified bacterium may remedy intestinal diseases

Inflammatory Bowel Disease - Growth hormone could promote growth and intestinal healing in children

Inflammatory Bowel Disease - High intake of red meat, alcohol may triple relapse rate in ulcerative colitis

Influenza - Biotechnology company begins shipping influenza vaccine to Canadian customers

Influenza - Flu is sending more and more to hospital

Influenza B Virus - New assay for antigenic characterization influenza B virus developed

Influenza Vaccine - Influenza and pneumococcal vaccination lower mortality in elderly

Influenza Vaccine - Roles of IgA and IgG in influenza control in respiratory tract studied

Influenza Virus - Immunokinetics in severe pneumonia due to influenza virus/bacteria coinfection

Information Management - Hispanic Commission plans to develop databank

Information Technology - ACS awarded fifth contract to administer Louisiana healthcare programs

Information Technology - Analysis software for chemical and biological data processing released

Information Technology - Bio information company adds proteomics division for research support

Information Technology - Bournemouth Hospital to install 3D imaging software for radiology services

Information Technology - Carefx joins the Citrix Alliance Partner Program

Information Technology - Claimsnet contracts with New York health plan

Information Technology - Daughters of Charity Health System selects the Ibex PulseCheck to automate ED

Information Technology - Digital content provider announces agreement with Mayo Foundation

Information Technology - Elsevier MDL collaborates to offer statistical visualization tool

Information Technology - Ernest Health inks contract for Keane's healthcare information system

Information Technology - Fiftieth healthcare customer chooses secure remote access

Information Technology - Gateway EDI chooses Claredi's in-stream transaction validation, routing system

Information Technology - Graham King joins Certification Commission for Healthcare Information Technology

Information Technology - India-based company signs agreement for distribution of life sciences software

Information Technology - Information technology solution selected by California hospital and clinic

Information Technology - New York Visiting Nurse Association awards wireless messaging contract

Information Technology - New lab software released

Information Technology - New software adopted by veterans group to improve process of informed consent

Information Technology - New website to help consumers with insurance complaints

Information Technology - North Texas Medical Center utilizes medication-use technology

Information Technology - Novel HIV glucosidase inhibitors developed with computer-aided technology

Information Technology - Partnership to increase nurses' knowledge of healthcare information technology

Information Technology - Pfizer selects company to provide Web-based learning solution

Information Technology - Pharma software provider announces appointment of outside auditor

Information Technology - Provider of analysis software for biotech investors announces Mehta partnership

Information Technology - Recently issued patent covers the use of support vector machines

Information Technology - Software provider and subsidiaries sign marketing agreements with InfraHealth

Information Technology - Solution launched to enable digital pathology

Information Technology - Surgical company recognized as leader in customer satisfaction

Information Technology - Tennessee healthcare company selects provider of HIPAA secure e-services

Information Technology - TrialMaster developer and Catalyst partner to expedite trial data

Information Technology - U.S. VA signs contract for audible prescription system

Information Technology - Vernier Adaptive Security Platform helps organizations meet HIPAA requirements

Insomnia - Positive results reported from Indiplon trial in elderly insomnia patients

Insulin - Discovery of fruit fly pancreas points to possible diabetes cure

Insulin Pumps - Health Canada approves Animas IR 1200 insulin pump for distribution

Interleukin - Expanded family of class II cytokines share IL-10 receptor-2 (IL-10R2) chain

Ischemia - Blocking the JNK pathway may be novel approach for treating myocardial ischemia

Isoforms - Fudion protein can promote myofibrillogenesis in hearts lacking tropomyosin

Joint Implants - New method measures the efficacy of bone cement X-ray contrast media

Joint Replacement - Researchers aim to create "living glue" for replacement joints

Kaposi Sarcoma - Peptide derived from eosinophil-derived neurotoxin induces apoptosis in KS cells

Klebsiella Pneumoniae - The Na+-citrate transporter CitS of K. pneumoniae has a pore loop structure

Knee Replacement - False aneurysm of the lateral superior genicular artery reported

Laboratory Techniques - New linear RNA amplification protocol works with very small samples

Language - Children follow same steps to learn vocabulary, regardless of language spoken

Learning - Study explores the machinery of forgetting fears

Legal Issues - Biotechnology company challenges validity of Benitec's Australian patent

Legal Issues - Blue Cross Blue Shield sues Missoula, Montana's only radiology practice

Legal Issues - Company adopts on-line registry for clinical studies; AG to close inquiry

Legal Issues - Court finds former baseball star not liable for endorsements in U.S. FTC action

Legal Issues - Court upholds MSNJ right to sue to stay acquisition of Oxford Health Plans

Legal Issues - Judge rejects suit on immigrants' healthcare in Los Angeles County

Legal Issues - Lee Regional Health System sues Univ. of Pennsylvania Medical Center

Legal Issues - Patent infringement complaint filed against analaytical instruments company

Legal Issues - Pharma company appeals court decision on human growth hormone patent

Legal Issues - Pharma company wins Lamisil patent infringement lawsuit against Dr. Reddy's

Legal Issues - Program for ill Hanford workers improved but still criticized by senators

Legal Issues - Self-insured surgeon sues Charleston Area Medical Center to keep privileges

Legal Issues - South Carolina man wins suit against state Department of Health

Leishmaniasis - Inhibitors of Leishmania mexicana CRK3 cyclin-dependent kinase screened

Leishmaniasis Vaccine - DNA-Salmonella vaccine protects against Leishmania major

Leukemia - Discovery of biological principle could lead to better cancer treatment

Leukemia - Mature B-cell acute lymphoblastic leukemia with t(9;11) translocation studied

Licensing - Schering AG pays $1 million option license fee to cardio-focused company

Life Science Resources - MichBio launches newly designed Resource Locator on web site

Limb Ischemia - Potential approaches to problems of critical limb ischemia are discussed

Lipid Studies - APOE*2 antiatherogenic lipid pattern is detected in a highly admixed population

Lipid Studies - Adlay seed extract has hypolipidemic effects in obese rats

Lipid Studies - Hypothalamic responses to long-chain fatty acids are nutritionally regulated

Listeria Outbreak -  Listeria monocytogenes isolated from cold-smoked fish products in Japan

Listeria Outbreak - Clone of L. monocytogenes serotype 4b implicated in food-borne listeriosis

Liver Cancer - Tumor genes cluster into two subsets that correlate to survival

Liver Fibrogenesis - Transforming growth factor-beta1 increases fibrillin-1 in rat liver cells

Liver Hypoxia - Novel multifunctionality of oxyradicals indicated

Long QT Syndrome - ICD therapy appropriate for pediatric patients

Longevity - Record number of Japanese over 100 years old in 2004

Lou Gehrig Disease - IND allowed for ALS treatment

Lower Limb Ischemia - Subintimal angioplasty effective in many cases

Lung Cancer - Anticancer drug HGS-ETR1 advances to phase II clinical development

Lung Cancer - Fibronectin may stimulate human lung carcinoma cell growth

Lung Cancer - Further classification of lung tumors may better predict survival

Lung Cancer - Study finds volatile biomarkers in lung cancer blood

Lung Cancer - Tumoral VEGF-C status correlates with non-small cell lung cancer prognosis

Lupus - Free vascularized fibular grafting for femoral head osteonecrosis effective

Lymphoma - Environmental conditions in early childhood have long-term effect on immunity

Macular Degeneration - Investigational New Drug application filed for macular degeneration trials

Malaria -  Anopheles malaria mosquitoes increase in relation to housing conditions

Malaria - Malaria research collaboration makes progress with model-based drug discovery

Malaria - Serum malondialdehyde levels are increased in Plasmodium vivax infection

Malaria Therapy - Molecular methods determine resistance to antimalarial drugs during epidemics

Malaria Vaccine - Subdomain of Plasmodium apical membrane antigen 1 ectodomain produced

Male Infertility - Cancer scientists make unexpected discovery

Malpractice Insurance - Doctors opt out of surcharge plan

Managed Care - Healthcare information provider offers managed-care focused primary research

Market Analysis - A large majority of Americans favor drug importation

Market Analysis - Aging population drives European orthopedic braces, supports market

Market Analysis - Most pharma companies devote half of research to strategic opportunities

Market Analysis - Special report looks at medical HMO trends

Materials - "Intelligent" box can keep temperature stable for vaccine transport

Medical Devices - Children's Heart Center installs pediatric cardio data management software

Medical Devices - Clinical studies phase for hearing implant device started in U.S. and Germany

Medical Devices - Companies announce strategic distribution alliance

Medical Devices - Drug discovery, biotech companies sign licensing and supply agreements

Medical Devices - Manufacturing, marketing agreement for stress urinary incontinence tape signed

Medical Devices - Methods for preservation of tissue antigenicity compared

Medical Devices - Optics company announces fourth quarter year end results

Medical Devices - Testosterone replacement gel available in U.S. FDA-approved metered-dose pump

Medical Devices - U.K. patient is first to receive implant of heart failure management device

Medical Devices - U.S. FDA approves expandable prosthetic titanium rib for children with TIS

Medical Devices - U.S. patent for rapid nucleic acid amplification awarded to university

Medical Error - New Mexico physician pleads guilty, will give up license over patients' deaths

Medical Facilities - Ascension Health, surgical group partner to develop ambulatory facilities

Medical Liability - HealthGate releases risk containment solution for hospitals, health systems

Medical Research - Beta version of capillary micro-preparative device completed

Medical Training - Medical schools tighten conflict-of-interest standards

Medicare - Public interest group calls for investigation of communications contract

Melanogenesis - Biosynthesis and release of epinephrine may lead to melanogenesis

Melanoma Vaccine - Five dose levels of monoclonal antibody melanoma vaccine compared

Melanoma Vaccine - GD3-L-KLH vaccine elicits antibody response in melanoma patients

Melanoma Vaccine - Role of CD8+ T-cell immunity in progression of melanoma reviewed

Meningitis Vaccine - U.S. Centers for Disease Control lift limits on childhood meningitis vaccine

Meningococcal Vaccine - Meningococcal conjugate vaccine reduces mortality in Scotland

Menopause - Free kit developed for new ways to manage menopause

Menstruation - Persistent organochlorine compounds not proven to disrupt menstrual cycle

Mental Health - Alexithymia may be linked to CVD via autonomic dysregulation process

Mental Health - Attention deficit adults report AD/HD has kept them from achieving life goals

Mental Health - Boost in adrenal DHEA release may improve symptoms in women with PTSD

Mental Health - California behavioral health center awarded highest rated NCQA accreditation

Mental Health - Linkage between chromosome 21q22 and bipolar disorder points to allele 2

Mental Health - New law on mental health treatment for children has surprising result

Mental Health - Psychological effects of hurricanes discussed by trauma psychologist

Mental Health - Public service announcements address mental health myths

Mental Health - Receptor expression in brains of suicide victims characterized

Mergers & Acquisitions - Acquisition of Chinese state-owned pharmaceutical company completed

Mergers & Acquisitions - Amedisys acquires Freedom Home Health in Virginia

Mergers & Acquisitions - Biotech company announces $2,500,000 asset sale to Accentia

Mergers & Acquisitions - Biotech demerger completed, key appointments reported

Mergers & Acquisitions - Crdentia acquires Care Pros Staffing, closes on Arizona Home & Healthcare

Mergers & Acquisitions - Dental company mails offers to purchase all common shares of Innova LifeSciences

Mergers & Acquisitions - Device company acquires soft tissue repair technology company

Mergers & Acquisitions - Encore Medical, implant company terminate acquisition/merger agreement

Mergers & Acquisitions - Eye Care International inks LOI with Photoscreener patent-holder

Mergers & Acquisitions - Graffinity Pharmaceuticals and MyoContract merge

Mergers & Acquisitions - Hampton Berkshire Insurance to acquire cancer-focused pharmaceutical

Mergers & Acquisitions - Health food and wellness group finalizes merger with All For A Dollar Stores

Mergers & Acquisitions - Health system to transition Suburban General Hospital to northern campus of AGH

Mergers & Acquisitions - Healthcare company acquires the Halstead Hospital and Hertzler Clinic

Mergers & Acquisitions - Hospital corporation agrees to sell Los Angeles property to its physicians

Mergers & Acquisitions - Medical device company acquired by semiconductor firm

Mergers & Acquisitions - Pharma company completes sale of vaccines business to ID Biomedical

Mergers & Acquisitions - Tri Supreme prescription laboratory joins opthalmic optical products company

Mergers and Acquisitions - Biopharmaceutical company to acquire Zycos Inc.

Mergers and Acquisitions - Diagnostics company to merge in all-stock transaction

Mergers and Acquisitions - Medical technology company acquires Haverhill Technology Group

Mergers and Acquisitions - Mobetron manufacturer and distributor to be acquired

Mergers and Acquisitions - National Surgical Care acquires California-based multi-specialty surgery center

Mergers and Acquisitions - Registration Statement on Form S-4 filed for King Pharmaceuticals acquisition

Metabolic Syndrome - New data presented for Crestor in patients with metabolic syndrome

Metastases - The coxsackie and adenovirus receptor modulates cancer cell migration

Methaemoglobinaemia - Nitrate offers health benefits

Microbial Contamination - Microbial biofilms prevalent on fresh produce and household surfaces

Microencapsulation - Peptide-derivatized shell-cross-linked nanoparticles evaluated

Microsporidiosis - Conserved Encephalitozoon aminopeptidase may be drug target

Migraine - Study shows treating migraines early with eletriptan provides greater efficacy

Migraine Headache - OTC migraine remedy makers adds two regional chains to list of retailers

Migraine Headache - Wholesalers place orders for over-the-counter migraine headache drug

Misconduct - Travel expenses spark investigation at Arkansas Health Department

Mitral Valve Function - Viscoelastic properties of mitral valve chordae can be explained morphologically

Molecular Analysis - Laboratory technologies converge to examine protein-DNA interactions

Molecular Biology - Grant issued for universal restriction enzyme, large DNA fragment assembly

Molecular Biology - Pericyte-derived NG2 proteoglycan is an early promoter of neovascularization

Mood Disorders - Neurosteroids may have therapeutic potential in women with affective disorders

Mosquito-Borne Disease - Gains made in controlling mosquito-borne diseases in Australia from 1972 to 2004

Mosquito-Borne Disease - Population genetics of Aedes aegypti mosquitoes from Cambodia summarized

Mucosal Immunization - RelB mediates TNF-induced up-regulation of polymeric Ig receptor

Mucosal Immunization - Transgenic tolerized T cells cannot aid B cells upon mucosal challenge

Multiple Myeloma - Bortezomib shows promise in clinical trials

Multiple Myeloma - CDC awards grant to fund blood cancer education program

Multiple Myeloma - Early intensive therapy beneficial for primary resistant myeloma patients

Multiple Myeloma - Research consortium awarded $1.5 million grant to support tissue and data banks

Multiple Sclerosis - FK506 reduces axonal and myelin damage in autoimmune encephalomyelitis

Multiple Sclerosis - Pregnancy-induced shift toward Th2 cytokines may help reduce MS exacerbation

Multiple Sclerosis - Small changes in the lipid composition of myelin seen as disease progresses

Multiple Sclerosis - Vaccine may be associated with increased risk of MS

Mumps Vaccine - Vaccine failure contributes to mumps outbreak in vaccinated children

Mutagenesis - A neurotrophin receptor p75 gene polymorphism associates with attempted suicide

Mutagenesis - NRF2 gene mutations may be involved in the etiology of human diseases

Mutagenesis - Radiation spawns genomic instability through cytokine induction

Mutation - Base substitutions in Escherichia coli are distinctive after irradiation

Myocardial Infarction - Coronary angioplasty soon after medical therapy could be best treatment

Myocardial Infarction - Inflammatory marker may be early sign of blood vessel blockages

Myocardial Infarction - Sarafotoxin 6c reduces myocardial infarct size

Myocardial Infarction - Study examined the relation of atherosclerotic plaques to the onset of MI

Myopia - Implanted lens sharpens blurred vision

Name Change - Pharmaceutical-research company changes name to clarify line of business

Nanotechnology - NCI announces major commitment to nanotechnology for cancer research

Neck Pain - 'What To Do About Neck Pain' report discusses diagnosis, treatment, exercises

Neonatology - High-tech pacifier being tested in hospitals may help preemies

Neurobiology - Scientists: Rembrandt's self-portraits suggest he probably had lazy eye

Neurodegenerative Diseases - TANGO: toward faster prognosis of Alzheimer and Parkinson diseases?

Neurology - M4 muscarinic receptors regulate dopaminergic neurotransmission

Neurology - Nerve growth factor regulates axonal mitochondrial transport

Neurology - Network properties of teratocarcinoma cell line-derived neurons determined

Neurology - Neuronal migration patterns in embryonic cortex reviewed

Neuropathy - FDA approves antidepressant Cymbalta for diabetic peripheral neuropathic pain

Neuroscience - CO-induced striatal hydroxyl radical generation characterized

Neuroscience - Effects of nicotine on VTA dopamine release characterized

Neuroscience - Expression of the mu-opioid receptor may be influenced by age, sex

Neuroscience - Haloperidol impairs human learning and error-related negativity

Neuroscience - Nitroxide radicals may have neurotoxic effects

Neuroscience - Optimized vectors will improve central nervous system ex vivo gene transfer

Neuroscience - Role of nuclear accumbens dopamine in acoustic startle clarified

Neuroscience - VEGF predicts the outcomes of patients with leptomeningeal metastasis

Neutropenia - Manufacturing agreement announced for neutropenia drug candidate

Newcastle Disease - Restriction enzyme-based assay can rapidly identify NDV strains

Nicotine Addiction - Agreement with Rite Aid Corporation forged to reduce underage cigarette sales

Norovirus Outbreak - Norovirus gastroenteritis longer in healthcare settings than in healthy persons

Nosocomial Infection - Four prevalent types of S. marcescens predominant in two hospitals in Poland

Nursing Education - Expanded nursing continuing education program announced

Nutrition - Food study finds diets get healthier over time

Nutrition - Prize for modern nutrition from the Federation of Swiss Milk Producers awarded

Nutrition - Research shows almonds increase intake of several important nutrients

Nutrition - U.S. soft drink consumption grew 135% since 1977, boosting obesity

Obesity - Environmental factors influence food consumption in unknowing consumers

Obesity - Genes, biology important in obesity fight

Obesity - LifeWise Heart Truth Challenge prize awarded

Obesity - New obesity research looks to Europe for answers

Obesity - Obesity epidemic was focus of London symposium

Obesity - Rise in childhood obesity has raised concerns about school lunch nutrition

Obesity - eBay bans book "Why Is America So FAT?", according to author Ben Kennedy

Obesity Epidemic - Environmental changes can reduce the obesity epidemic

Obesity Genomics and Genetics - Common variants in 5' region of leptin gene associated with BMI in men

Obesity Genomics and Genetics - Genomics of body weight regulation reviewed

Obesity Pathogenesis - Diet-induced obesity downregulates apolipoprotein A-IV gene expression

Obesity Pathogenesis - Molecular and cellular correlates mechanisms of ingestive behavior reported

Obesity Pathogenesis - Obesity alters the dynamics of circulating ghrelin, adiponectin, and leptin

Obesity Pathogenesis - Roles of cholecystokinin A receptors in energy balance investigated

Obesity Risk Factor - Policies and consequences related to obesity in the U.S. reviewed

Obesity Therapy - Brazilian herbal medicines reduce weight gain or cholesterol levels

Obesity Therapy - Glucagon-like peptide 1 and eating reviewed

Obesity Therapy - Role of conjugated linoleic acid in obesity control outlined

Obesity Therapy - Tetrahydronaphthyl thioureas - potent appetite suppressants - synthesized

Obesity and Diabetes - Estrogen restores utero-ovarian indices in hypercytolipidemia

Obesity and Diabetes - Ghrelin gene expression higher in fetal pancreas compared with fetal stomach

Obesity and Diabetes - Interactions of hormones and ingestive behavior reviewed

Obesity and Diabetes - Mutant IRS expression inhibits metabolic and mitogenic signaling of insulin

Obstetrics - Elective cesarean delivery still a debatable issue

Obstetrics - Embolization for postpartum hemorrhage is efficacious, safe

Obstetrics - Ex utero intrapartum treatment procedure safe for mom and baby

Obstetrics - Increased adenosine primary factor for hyperuricemia in twin pregnancies

Obstetrics - Intrahepatic cholestasis of pregnancy is high-risk complication

Obstetrics - New perinatal program helps nurses reduce risks during delivery

Obstetrics - Selenium protects against environmental chemical stress in pregnant women

Obstetrics - Sensory block levels during cesarean section evaluated

Obstetrics - Stress during gestation induces lasting effects on emotional reactivity in rats

Obstetrics - Study suggests cannabinoids may be linked to ectopic pregnancy

Obstructive Sleep Apnea - Flow generators launched to treat OSA

Occupational Health - Bronchiolitis obliterans syndrome found in popcorn production plant workers

Oncology - Adenoviral p53 gene transfer and chemotherapy fight ovarian cancer cell growth

Oncology - Apoptosis induction therapy for breast cancer requires p21 signaling

Oncology - Heparin-binding epidermal growth factor-like growth factor stimulates cancer

Oncology - Putative tumor suppressor RASSF1A modulates microtubule dynamics

Oncology - Suicide gene therapy containing recombinant viral vector attacks sarcoma

Orthopedics - Joint-specific instruments provide better arthroscopic access to the hip

Orthopedics - Medical device company acquired by ArthroCare

Orthopedics - Partnership to launch publication for U.S. orthopedic surgeons

Osteogenesis - Vascular endothelial growth factor encourages graft-induced bone formation

Osteomyelitis - A novel hydroxyapatite has high antibiotic release

Osteomyelitis - Controversies in managing osteomyelitis of the foot in diabetes reviewed

Osteoporosis - "Mighty mouse" helping find ways to build bone, prevent bone loss

Osteoporosis - Disease better understood by more highly educated, younger in Polish group

Osteoporosis - Economic burden of osteoporosis calculated in Latin America

Osteoporosis - Improved BMD in soy isoflavone/high calcium regimen due mostly to calcium

Osteoporosis - Maintaining body weight in postmenopause protects against bone loss

Osteoporosis - Rib fracture predicted to double elderly Finns' hospitalization in 3 decades

Osteoporosis - Risk factors identified for low BMD of calcaneus, distal radius in Korean group

Osteoporosis - Soy isoflavone + moderate exercise prevents increased body fat, bone loss

Osteoporosis - Stiffness is best predictor of hip fracture among ultrasound parameters

Osteoporosis - VDR gene polymorphisms and bone loss rate association investigated

Otitis Media - Researchers quantify active Eustachian tube function

Otorhinolaryngology - Cone-beam CT system facilitates maxillary implant treatment

Otorhinolaryngology - ESPN mutations are linked to autosomal recessive deafness

Otorhinolaryngology - Simple technique devised for tracheo-esophageal fistula closure

Outsourcing - Report: Drug-discovery technology is next offshore service

Ovarian Cancer - EGFR-1 not a prognostic indicator in advanced primary ovarian epithelial cancer

Ovarian Cancer - Fund invests to develop ovarian cancer early detection technology

Ovarian Cancer - Lower ERbeta and PR immunoreactivity observed in cancerous epithelial tissue

Ovarian Cancer - Novel target found for detecting ovarian cancer in blood

Ovarian Cancer - Potential biomarkers identified by gene expression technique

Pain Management - Biopharmaceutical company completes phase III enrollment for low back pain study

Pain Management - Pain drug market offers companies significant commercial opportunity

Pain Management - Patient-controlled analgesia feasible during burn dressing changes

Pain Management - Poll finds back pain sufferers waiting for approval of artificial discs

Pain Management - Use of regional anesthesia in orthopedics reviewed

Pain Medicine - Nursing home companies, QI groups, Medicare work together to reduce pain

Pain Medicine - Splitting muscle relaxant could cause inconsistent dosing, unpredictable relief

Pancreatic Cysts - Cyst fluid analysis useful for differential diagnosis of pancreatic cysts

Pancreatic Insufficiency - TheraCLEC selected for FDA's Continuous Marketing Application Pilot 2 program

Parainfluenza Virus - Nucleolin plays important role during parainfluenza virus type 3 cellular entry

Parasitology - Microarray-based assay detects and genotypes protozoan parasites

Parkinson Disease - Laboratory releases of polyclonal antibody to predict emergence of Parkinson

Parkinson Disease - Pharma companies launch Parkinson disease study

Patents - Bariatric surgeons granted U.S. patent for gastric bypass surgical procedure

Patents - Company granted European patent for DX-88

Patents - GTG reports on the current status of legal action to protect its patents

Patents - Medical technology company announces favorable patent infringement decision

Patents - Pharma announces settlement in HIV patent dispute with Roche

Patents - Tissue engineering firm announces approval of patent in Japan

Patents - U.S. Patent Office agrees to re-examine PharmaStem cord blood stem cell patents

Patient Education - Evanston Northwestern Healthcare promotes breast cancer early detection

Pediatric Cardiology - Repolarization abnormalities studied in children with structurally normal hearts

Pediatric Eye Maladies - Excimer lasers safe, effective for pediatric eye maladies, study shows

Pediatric Myocarditis - Study describes predictors of outcome of myocarditis in pediatric patients

Perception - Brain has center for detecting sound motion

Perception - Features or creatures: visual expertise taps same neural networks

Peripheral Arterial Disease - Patients with peripheral arterial disease are currently being undertreated

Peripheral Arterial Disease - Study reports on peripheral arterial disease related amputations

Personnel - Alastair Wood joins immunotherapeutics company board of directors

Personnel - American Healthways' board of directors appoints new member

Personnel - Biopharmaceutical company announces appointment of chief financial officer

Personnel - Biopharmaceutical firm announces new management, board members

Personnel - Biopharmaceutical firm board of directors appoints Evan Levine president, CEO

Personnel - Biopharmaceutical firm's new marketing team to focus on product innovations

Personnel - Biotech company appoints Donald J. Santel CEO

Personnel - Biotech company appoints Richard Wills to board of directors

Personnel - Biotech company names Charles R. Eyler VP of finance

Personnel - Biotech company names Peter Savas as board chairman and CEO

Personnel - Biotech names Graham Strachan chairman of the board

Personnel - Blue Cross, Blue Shield of Florida appoints senior VP, human services group

Personnel - Canadian biotech firm appoints new CFO

Personnel - Cancer therapy company announces resignation of VP/medical director

Personnel - Cancer-focused biotech company names Randall B. Riggs VP of business development

Personnel - Christopher Hannon appointed to board of healthcare real estate investment trust

Personnel - Company specializing in autologous cellular therapies appoints president and CEO

Personnel - David Henderson, chief executive of AEGON UK to retire in March 2005

Personnel - David M. Kreiss joins the leadership team at Health Dialog

Personnel - Device company forms scientific advisory board

Personnel - Diagnostics company announces new chairman of the board

Personnel - Douglas E. Williams named executive VP, chief scientific officer by biotech firm

Personnel - Dr. Allon Guez joins board of directors; Paul Guez resigns

Personnel - Dr. Peter Lee to leave AgriGenesis

Personnel - Eric von Stetten named VP of densitometry by radiology services company

Personnel - Former Clemson dean appointed to mental health commission

Personnel - GTESS Corp. names VP, key accounts

Personnel - Generic pharmaceutical firm announces management appointments

Personnel - Genetics company announces that chief scientist is stepping down

Personnel - Genomics company adds Brill to business development advisory board

Personnel - Genomics company hires senior UCLA cancer researcher

Personnel - Glucose-monitoring company appoints new U.S.-based CEO: Daniel Goldberger

Personnel - Gregory A. Arms appointed senior vice president of healthcare services company

Personnel - Hillenbrand names Mark D. Ketchum and Eduardo R. Menasce to board

Personnel - Horizon Health Corporation announces resignation of chief financial officer

Personnel - Imerica Life and Health Insurance announces new chief insurance officer

Personnel - Indiana man appointed as Nebraska's new behavioral health administrator

Personnel - James Harper appointed to board of directors of pharmaceutical company

Personnel - Jeremy Hindle appointed as ceded reinsurance and underwriting risk manager

Personnel - Jim W. Kramer named VP of business development by medical device company

Personnel - John H. Freeman named COO of life science consulting company

Personnel - Life sciences IT firm appoints new VP of marketing

Personnel - Managed care company names executive vice president of central Pennsylvania

Personnel - Marilyn Norman named VP of marketing, distribution management by insurance group

Personnel - Matthew W. Emmens appointed to pharmaceuticals board of directors

Personnel - Medical laser manufacturer announces new company president

Personnel - Michael Klein named human resources director by anesthesia services company

Personnel - Molecular diagnostics company announces new board member

Personnel - Nationwide Health Properties names new senior VP, chief portfolio officer

Personnel - North American sales manager hired by nanotechnology company

Personnel - Nutrition technology company names president and CEO

Personnel - Oncology company expands board, appoints new independent director

Personnel - Oncology company names chief medical officer

Personnel - Online doctor-patient communication services provider appoints COO

Personnel - Oral spray vitamins manufacturer announces interim chief executive officer

Personnel - Pharma company appoints chairman, CEO and president to its board of directors

Personnel - Pharma company reports changes to executive management team

Personnel - Pharmaceutical company appoints vice president clinical development

Personnel - Pharmaceutical firm appoints H. Ward Wolff as chief financial officer

Personnel - Pharmaceutical firm elects Sandra Fenwick to board of directors

Personnel - Pharmaceutical firm makes hundreds of new appointments

Personnel - Pharmaceutical firm names new VP, global quality and regulatory compliance

Personnel - Pierre Tran appointed VP, chief medical officer by biopharmaceutical company

Personnel - Sleep disorder treatment provider announces promotion

Personnel - Specialty pharmaceutical manufacturer names chief executive officer

Personnel - Steven D. Skolsky named chief executive officer of viral disease-focused company

Personnel - The Mosaic Company names executive vice president, chief financial officer

Personnel - V. Randy White named chief executive officer by applied genomics company

Personnel - William Heiden appointed CEO of metabolic disorders-focused pharmaceutical firm

Personnel - Wilson Totten appointed CEO of merged, re-named pharmaceutical company

Personnel - With Celltech merger complete, Jacobs steps back, becomes chairman

Personnel - eClinical research organization expands business development team

Pertussis - Bispecific monoclonal antibody detects causative agent of whooping cough

Pertussis - South Dakota sees increase in whooping cough cases

Pertussis - Whooping cough cases at 635 in North Dakota

Pharmaceutical Branding - Research shows modifying treatment guidelines propels brands to No. 1

Pharmaceutical Research - Data on alternative for pulmonary arterial hypertension patients presented

Pharmacology -  ME10092 cardioprotective effect may be mediated by modulation of NO production

Philanthropy - Trick-or-Treat for UNICEF campaign 2004 to help children in Latin America

Plague Vaccine - Genetics of variations of Yersinia pestis biovars presented

Pneumococcal Vaccine - Anti-polysaccharide IgG linked to pneumococcal disease risk in HIV-1

Policy - More attention needed to translate research into health improvements

Polyamines - Studies of polyamines could extend their application to cancer diagnosis and treatment

Polycystic Syndrome - Review: Primary clinical end points should be focus of clinical trials

Post-traumatic Stress Syndrome - Korean War veterans still affected by war trauma

Postoperative Ileus - FDA accepts Entereg (alvimopan) NDA for review

Poxvirus Vaccine - 4-1BB and OX40 stimulation enhance T-cell responses to poxvirus vaccine

Preeclampsia - Early changes in IGF-I synthesis in pregnancy may be involved in hypertension

Prenatal Health - PrimaCare ONE prescription prenatal product launches

Prescription Drug Costs - Arkansas program cuts medications to save money

Product Licensing - Cardiovascular-focused company expands license agreement with Genzyme Corp.

Product Licensing - Companies announce revision of licensing agreement for cancer cell line vaccines

Product Licensing - Company licenses exclusive rights to cinnamylidene-anabaseines compounds

Product Licensing - Company licenses promising cancer detection technology from UMMS

Product Licensing - Crucell and DSM announce PER.C6 licensing agreement for antibody production

Product Licensing - GTESS to license Medstat-Thomson Healthcare decision-support solution

Product Licensing - Rights to proteins with antiviral and anti-inflammatory disease licensed

Production Distribution - HemoSense inks distribution agreement for point-of-care coagulation diagnostics

Prostate Cancer - "Hedgehog" signal distinguishes lethal from localized prostate tumors

Prostate Cancer - Foundation reports new partnerships for prostate cancer awareness month

Prostate Cancer - New York Yankees legend Lou Piniella works to raise prostate cancer awareness

Prostate Cancer - Report links elevated levels of hedgehog signaling to metastatic prostate cancer

Prosthetic Care - Chicago receives new 3D laser-scanning technology

Protein Analysis - Fluorescent puromycin conjugates explore protein expression in vivo

Protein Inhibition - Dual-function decoy Met receptor blocks tumor angiogenesis and proliferation

Protein Kinase C - Agonists protect cells in vitro, exert little protection in an in vivo model

Protein Synthesis - Inhibition may be a key mechanism by which hypertrophic growth can be controlled

Protein Synthesis - Recombinant baculovirus activates VEGF production in silkworm larvae

Proteomics - GDF9 regulates granulosa cell gremlin expression

Proteomics - Protein concentration at laser-patterned nanoporous membranes characterized

Psychiatric Disorder - Mutations in major neuroligin genes are not frequent in autism

Psychiatry - Maternal schizophrenia and affective psychoses affects offspring's development

Psychological Stress - Changes in rats correspond to changes relevant to CV diseases in humans

Public Health - Health officials search for culprit behind mysterious, itchy bites

Pulmonary Arterial Hypertension - Enrollment target reached for STRIDE-2, pivotal phase III trial for Thelin

Pulmonary Medicine - Electroporation-mediated HGF gene transfer ameliorates pulmonary fibrosis

Pulmonary Medicine - Pigment epithelium-derived factor is a critical mediator of pulmonary fibrosis

Quality Assurance - Medical transcriptionists endorse raising professional standards

Quality Assurance - Most eligible hospitals are reporting quality-of-care data

RNA Research - Hepatitis C virus NS3 helicase RNA aptamers further diagnosis and research

RNA Vaccine - Messenger RNA-based vaccines reviewed

RNA Virus - Calicivirus 3C-like proteinase inhibits cellular translation by PABP cleavage

Radiotherapy - Heat shock protein 27 protects human cells against ultraviolet C-mediated death

Rankings - Medco ranked No. 1 pharmacy benefits manager, research results show

Receptor Kinases - GRK 3 may have a role as a negative feedback regulator

Receptor Studies - Activity of Plexin-A1 receptor regulated by Rac

Reconstructive Surgery - Effective technique devised for reconstruction of ischemic digits

Reconstructive Surgery - Revascularization of nose alar wing feasible after near-complete amputation

Rectal Cancer - Reactive oxygen species detected during H2 O2 decomposition in rectal cancer

Regulatory Issues - FDA testing limits of medical technology

Regulatory Review - Pharmaceutical firm reports on meeting with FDA about manufacturing facilities

Reimbursement - AAHomecare examines OIG report on Medicare payment for home oxygen

Reimbursement - Increased use of generic drugs cuts states' healthcare costs

Renal Arteriovenous Fistula - Novel TAE technique devised for fistula closure

Renal Failure - Oxygen-regulated protein 150 protects renal cells from injury

Renal Therapy - Prismaflex, a new system for renal intensive care, launched

Renal Transplant - Automated test to monitor Rapamune (sirolimus) submitted to FDA

Renin - The diversity of renin actions is reflected by its complex control

Reproductive Medicine - Activity of p38 MAPK during oocyte maturation characterized

Reproductive Medicine - Support high for insured family planning services in U.S., but not abroad

Research Funding - Garfield County, Colorado, recommends spending oil company fine on research

Respiratory Synctial Virus - RSV outbreak in pediatric ICU caused by persistent viral shedders

Restensosis - Moderate alcohol consumption cuts rate of further narrowing after heart surgery

Restless Legs Syndrome - Ropinirole reduces sleep disturbances for patients with restless legs syndrome

Retinopathy - Interleukin-18 knockout mice display abnormal retinal vascular development

Retrovirus - TRIM5 alpha genes encode Ref1 and Lv1 retroviral restriction factor activities

Retrovirus Research - FIV nuclear protein Orf-A expresses properties similar to HIV-encoded Vpr

Rett Syndrome - Alteration of NGF levels may explain altered ventricular repolarization

Rheumatoid Arthritis - Agreement announced for rheumatoid arthritis genotyping study

Rheumatoid Arthritis - EBV, CMV in synovial tissue determined by RNA-, DNA-in situ hybridization

Rheumatoid Arthritis - FDA approves VIOXX for once-daily treatment of JRA

Rheumatology - Primary total prostheses for rheumatoid elbow compared

Ricin Vaccine - Novel route to an anti-ricin vaccine reported

Robotics - Muscle activity at the elbow is modified to reduce elbow positional deviations

Robotics - Robotically positioned transcranial magnetic stimulation system is accurate

SARS - Chemical genetics identifies SARS inhibitors

SARS - NIH awards grant to develop new antibodies targeting SARS

SARS - Phase I human clinical testing of SARS vaccine update offered

SARS - Severe acute respiratory syndrome may be complicated by spontaneous pneumothorax

SARS Coronavirus - Novel cell lines identified for SARS-CoV diagnostics or basic research

SARS Vaccine - Glycan arrays lead to discovery of autoimmunogenic activity of SARS-CoV

SARS Vaccine - Severe acute respiratory syndrome in China reviewed

Salivary Gland Cancer - Novel gene amplifications identified via CGH microarray

Salivation - M-3 muscarinic acetylcholine receptor is a target for xerostomia gene therapy

Schizophrenia - Link with RGS4 gene confirmed in Irish high-density families

Seasonal Affective Disorder - People with SAD have lower retinal sensitivity than normal controls

Sendai Virus - Phosphoprotein binding site on Sendai virus protein mapped

Senescence - Exposure to CrVI alters human cell senescence biomarkers in vivo and in vitro

Sexual & Reproductive Health - Company reports more than 2800 Vasclip implantable devices shipped

Sexual & Reproductive Health - Drug delivery technology company announces upcoming presentations

Sexual & Reproductive Health - Elders says churches should promote sex education

Sexual & Reproductive Health - Film, documentary, novel focus attention on Kinsey Institute

Sexual & Reproductive Health - U.N. says billions more dollars needed to meet goals on sexual health

Sexual Dysfunction - Interim results reported for phase II study using Tostrelle gel

Sexual Dysfunction - Researcher offers promising treatment for premature ejaculation

Shigellosis Vaccine - Novel immunogenic proteins of Shigella flexneri identified

Shortness Of Breath - CE Mark granted for new emergency department diagnostic test

Skin Care - Anti-aging tips for wrinkles issued from cosmetic surgery group

Sleep Disorders - Sleep specialist offers new tips

Sleep Disorders - Snoring risk differs between boys and girls

Sleep-Related Breathing Disorders - Sleep-related breathing disorders are a prognostic factor after stroke

Smallpox - FDA clears IND for an attenuated smallpox vaccine candidate

Smallpox Vaccine - Agent-based analysis of smallpox preparedness performed

Smoking Cessation - Health insurance plans extend efforts to end tobacco use, study shows

Smoking Cessation - Quitting smoking has more success with clinician support

Smoking Cessation - Study finds youth in tobacco states receptive to ads to reduce smoking

Sociology - Is volunteering the blueprint for bliss?

Sociology - Researcher looks at racial identity as part of healthy lifestyle

Spinal Cord Injury - Biotechnology company welcomes newest member to Procord Study Steering Committee

Spinal Degeneration - Study evaluates mechanical damage in the intervertebral disc annulus fibrosus

Spinal Injury - Florida program improves quality of services for traumatic brain injury patients

Sports Medicine - Anticipatory response ensures that thermal homeostasis is maintained

Sports Medicine - Eating and menstrual disorders affect BMD in elite female runners

Staffing - Kaiser Permanente, Florida Hospital, and orthopedics company to use Hire.com

Stem Cell - Public support for stem cell research increases according to poll

Stem Cell Research - BMP signaling initiates neural crest differentiation in embryonic CNS stem cells

Stem Cell Research - Donor cell CD26 expression negatively regulates homing and engraftment

Stem Cell Research - Fetal sheep model assesses full differentiative potential of human stem cells

Stem Cell Research - Magnetic nanoparticles used for mesenchymal stem cell expansion

Stem Cell Research - Mesenchymal stem cells can differentiate into retina-like structure

Stem Cell Research - Novel method allows axons to regenerate across the dorsal root entry zone

Stem Cell Research - Osteoclasts produced in three-dimensional bone marrow culture system

Stem Cell Research - Rituximab improves HSCT response in rheumatoid arthritis patients

Stem Cell Research - mTOR essential for early embryo and embryonic stem cell growth and proliferation

Stem Cell Transplantation - Allogenic SCT patients have more fatigue compared with autologous SCT patients

Stem Cell Transplantation - Implanted stem cells tracked using radio-labeled transferrin scintigraphy

Stem Cell Transplantation - Mental, physical decline after stem cell transplant is temporary, study shows

Stents - Company gives positive report of AMS at 6 months follow-up

Stock Market - Pharmaceutical company regains NASDAQ listing compliance

Stock Market - Zonagen Stock to Trade on NASDAQ Small Cap Market

Streptococcus - Major EU project shows "killer bacteria" more common than expected

Streptococcus Vaccine - Cholera toxin-pneumococcal surface adhesin fusion protein characterized

Streptococcus Vaccine - Group A streptococcal pharyngitis serotype surveillance reported

Streptococcus Vaccine - Influenza vaccine protects against lethal Streptococcus superinfection

Stroke - Discovery is gateway to new stroke treatments for brain disorders

Stroke - FDA approves new carotid stent system

Substance Abuse - Marijuana use continues to decline in 12-13 age group, 2003 abuse survey shows

Substance Abuse - Marijuana-like chemicals in the brain calm neurons

Suicide - Study highlights potential link between schizophrenia and suicide in China

Supplements - Nutritional-products maker earns certification from NFL and NFLPA

Systemic Lupus Erythematosus - Cancer drug shows promise against lupus

Systemic Lupus Erythematosus - Company announces publication of Prestara GL95-02 clinical trial results

Systemic Lupus Erythematosus - Rituximab drug shows promise against lupus

Tachycardia - The clinical approach should always consider the clinical context of arrhythmia

Tele-health - Wireless care improves monitoring of elderly and disabled people

Telomeres - Expression of telomerase RNA template is limiting

Tendon Repair Model - Running peripheral sutures increase strength of oblique tendon repairs

Testosterone - Drug for men with low testosterone tested in phase 1/2 safety, efficacy study

Thrombogenesis - The platelet integrin alphaIIb beta3 has three-dimensional features

Thrombosis - Guidelines offer new recommendations for travelers

Thyroid Surgery - Predictors of difficult tracheal intubation identified

Tick-Borne Disease -  Anaplasma re-infection produces milder disease than initial infection

Tissue Engineering - Novel culture system improves quality of neotissues

Tissue Regeneration - Hydroxyapatite hybrid coatings on a bone scaffold can release drugs

Tobacco Use - ACP1 genotype in infants modifies harmful effects of maternal smoking

Tobacco Use - Epac gene variations may contribute to the risk for nicotine dependence

Tobacco Use - Gender affects long-term efficacy of nicotine replacement therapy

Tobacco Use - Gender, smoking expectancy, and readiness to quit in smokers studied

Tobacco Use - Polysaccharide excipients in adhesive tablets tested for nicotine release

Tobacco Use - Prenatal nicotine exposure causes persistent changes in cell development

Tobacco Use - Smoking before birth of first child not linked to higher breast cancer risk

Tobacco Use - Smoking results in low plasma levels of vitamin C in mother and newborn

Total Hip Arthroplasty - Antimicrobial therapy is needed to treat infected joints

Total Hip Arthroplasty - Hip implant wear simulator is valid for comparing wear particles

Total Hip Arthroplasty - Swing phase loads affect wear of metal-on-metal hip implants

Total Joint Arthroplasty - Titanium implant surface can be modified to promote bone ingrowth

Toxicology - Aprotinin protects against BT venom-induced cardiopulmonary toxicity

Toxicology - Bisphenol A irreversibly inhibits some cytochrome P450 forms

Toxicology - Environmental estrogens can cross easily into placenta

Toxicology - Genomic effects of AzaC and dioxin characterized

Toxicology - Kinetics of DEHP and metabolite characterized

Toxoplasma - Novel strategy detects Toxoplasma gondii oocyst in water

Toxoplasmosis Vaccine - GRA4 or ROP2 protein partially protects against toxoplasmosis

Tracheal Stenosis - Self-expanding nitinol stents useful for non-surgical treatment

Transfusion - Acute lung injury is the third most common cause of transfusion-associated death

Transgenics - Lentiviral gene transfer into oocytes produces transgenic cattle

Transplant Medicine - Fruit fly model of diabetes has future implications for islet transplantation

Transplant Medicine - NIAID forms clinical consortium to improve success of organ transplants

Transplant Medicine - Risk of developing cancer after transplantation reduced with mTOR inhibitors

Tremor - Agilect reduced tremor and severity of "off" time in Parkinson patients

Trends - Cholesterol drugs may open door for more OTC switches

Tuberculosis - Tuberculous spondylodiscitis diagnosed in the absence of pulmonary disease

Tuberculosis Vaccine -  M. tuberculosis peptide recognized by T cells characterized

Tuberculosis Vaccine - Microparticles adsorption enhances protection of TB vaccine

Tuberculosis Vaccine - Two-plasmid system for expression of mycobacterial proteins developed

Tumorigenesis - Nutrients regulate cell cycle progression

Turner syndrome - Rate of prenatal detection by ultrasound high in European population

Type 2 Diabetes - Exubera controls blood glucose levels over 2-year period in diabetes study

Urinary Incontinence - 3D-US reliably measures postpartum urine retention

Urinary Incontinence - Gynecologists: Suburethral tape via obturator route is best insertion method

Urinary Tract Infection -  Proteus mirabilis structural fimbrial proteins elicit antibody response

Urinary Tract Infection - Anti-bacterial responses in urinary tract infections investigated

Urinary Tract Infection - Antimicrobial susceptibility of UTI pathogens has improved in northern Israel

Urology - Technology firm kidney stone technology highlighted at urology conference

Uterine Leiomyomas - Clinical trial for drug therapy has completed enrollment

Vaccine Delivery - Influenza virosomes are efficient for adjuvanted vaccine delivery

Vaccine Development - Quality of CD8+ T-cell memory is important

Vaccine Safety - Human exposure to raccoon pox vaccine vector leads to limited infection

Vaccinia Virus Vaccine - Mitogen-activated protein kinase pathway needed for vaccinia growth

Vaginal Yeast Infection - Ferring, Inc., receives approval to market Gynazole-1 in Canada

Vascular Contractility - Vascular smooth muscle does not react to titanium dioxide

Vasodilators - Cellular mechanisms underlying relaxant effect of urocortin are characterized

Vector-Borne Disease - Proteins show promise for mosquito control

Vector-Borne Disease - Research uncovers new facts about odor detection in insects

Vector-Borne Disease - Study cautions against using sunscreen-DEET combinations

Ventricular Tachyarrhythmia - ICD treatment may not prevent postoperative recurrence

Veterinary Medicine - Fort Dodge Animal Health to voluntarily recall ProHeart6

Violence - European Union urges U.N. inquiry into allegations of genocide in Sudan

Viral Genomics - Genetic suppressor elements offer a new approach for treating rabies virus

Viral Genomics - Genome studies question the origin of Dominican Republic dengue virus strains

Viral Genomics - Human TT virus not related to intravenous viral transmission in Portugal

Virology - A strategy of combining antiangiogenesis with oncolysis eradicates cancer

Virology - C-type lectins capture and transfer hepatitis C virus infectious virions

Virology - HIV-1 Vif: Multiple ways to outsmart the body's defenses?

Vitiligo - PUVA therapy-induced lentigine development reported

Water Pollution - Biosensor detects seven sulphonamides in drinking, ground, and surface water

Water Pollution - Nickel may affect structure and function of river biofilm communities

Water Quality - IJC releases Twelfth Biennial Report on Great Lakes Water Quality

Water-Borne Illness - Byproduct of water-disinfection process found to be highly toxic

Weight Control - Adiposity signals, genetics, and body weight regulation in humans reviewed

Weight Control - PPAR-gamma agonism increases capacity for thermogenesis

Weight Loss - Dental practice brings weight loss device to Boulder/Denver area

West Nile Virus - Company begins treatment of West Nile Virus

West Nile Virus - Drop in West Nile cases could signal worst is over for Texas

West Nile Virus - Elkhart County, Indiana, resident dies after West Nile infection

West Nile Virus - Immunity to West Nile virus reviewed

West Nile Virus - Kansas reports West Nile death, first of year in the state

West Nile Virus - Michigan's fourth, fifth human cases of West Nile confirmed

West Nile Virus - More West Nile virus cases reported in South Dakota

West Nile Virus - Seventeen people test positive for West Nile in Nebraska

West Nile Virus - St. Louis County woman is first West Nile-related death in Missouri

West Nile Virus - Tehama resident is 15th Californian to die of West Nile

West Nile Virus - Third Idaho man tests positive for West Nile virus

West Nile Virus - Third West Nile death reported in New Mexico

West Nile Virus - Three more cases of West Nile virus confirmed in North Dakota

West Nile Virus - Twenty-three new cases of West Nile in past week in Arizona

West Nile Virus - West Nile infections down to three this year in Ohio

West Nile Virus - West Nile not direct cause of man's death in Wisconsin

Women's Health - Electronics company and health association announced distribution agreement

Women's Health Research - Univ. of South Dakota program targets women's health issues

Wound Care - Alpha(v) integrin overexpression causes abnormal scarring

Wound Care - Dendrimer conjugates offer immunomodulation and reduced scar tissue formation

Wound Care - Maggot therapy linked with reduced postoperative wound infections

Wound Care - Microfoams the best treatment for varicose ulcers

Wound Healing - Bioresorbable nanofibers may be drug delivery systems for wound healing

Yellow Fever Vaccine - Fibrinogen, CRP, and IL-6 responses to yellow fever vaccine vary

Youth Sports - Iraq sending officials to international meeting on youth sports

Zoology - European common frog found to use novel mating strategy

Zoonosis - Characteristics of M. succiniciproducens may be exploited for industry

Zoonosis - New malaria vector species discovered in Africa

Zoonosis - WHO discusses disease response strategies

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