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Health and Medicine Week

Susan Hasty, Publisher

Table of Contents . . . October 18th, 2004

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Health and Medicine Week | Other Publications

Addiction Medicine - Caffeine withdrawal recognized as a disorder

Aging - Mental health problems in assisted living residents higher than expected

Epidemiology - Study: World's poorest young women overlooked by public health campaigns

Geriatrics - Use of growth hormone for delaying aging questioned

Health Promotion - Study explores marital partners' perspectives of health-related exchanges

AIDS/HIV Diagnosis - Rapid and conventional testing methods for HIV screening compared

AIDS/HIV Research - Classic AIDS diagnosed in sooty mangabey after an 18-year natural infection

AIDS/HIV Vaccine - HLA class I serotypes important in vaccine efficacy assessments

AIDS/HIV Vaccine - Parenteral and mucosal DNA vaccination enhances SHIV infection control

AIDS/HIV Vaccine - Site mapping in HIV genome may provide new approach to vaccine design

Abdominopelvic Actinomycosis - IUD often a concomitant factor in tumoral syndrome due to bacterial infection

Accreditation - ActiveHealth receives URAC disease management accreditation

Acute Otitis Media - Mastoidectomy during cochlear implant does not reduce ear infections

Addiction Medicine - Full enrollment reached in phase II trial of CYT002-NicQb for nicotine addiction

Addiction Medicine - Smoking and methadone use together are factors in neonatal abstinence syndrome

Adenovirus Vaccine - Simian virus-tainted adenovirus vaccine does not increase cancer risk

Adolescent Health - Study adds to evidence supporting sports, positive sexual behavior/health link

Advanced Cancer - HGS-ETR2 trials demonstrate safety, tolerability in advanced cancer patients

Adverse Drug Events - Fasting during Ramadan could cause problems for Muslim patients

African Sleeping Sickness - Enrollment completed for clinical trial of DB289 in African sleeping sickness

Aging - Combination of Mediterranean diet, healthy lifestyle means longer life

Air Pollution - Exposure-response functions indicate increases in respiratory symptoms

Airway Obstruction - Microdebrider more effective at treating pediatric airway

Alcoholic Cardiomyopathy - Review summarizes the role of acetaldehyde in alcoholic cardiomyopathy

Alcoholism - Alcohol-induced genetic changes identified in individual human brains

Alcoholism - Excess drinking shortens life by 30 years

Alcoholism - Parental involvement can help prevent underage drinking

Alcoholism - Simple interventions for ER patients could help reduce excessive drinking

Alcoholism - Younger drinkers more prone to problem behavior later

Allergies - New wheat-free cookbook reinvents author's favorite recipes

Alternative and Complementary Medicine - Health-Mat shown to stimulate T cell proliferation in blood samples

Alzheimer Disease - AD disease is not accelerated aging

Alzheimer Disease - Brightly colored cups, plates spur consumption in advanced AD patients

Alzheimer Disease - Cholesterol-lowering statin drugs emerge as having Alzheimer application

Alzheimer Disease - Hospital reports increase in number of people with mild, consistent memory loss

Alzheimer Disease - Human blood sample bank launches Alzheimer disease genetic collection

Alzheimer Disease - Promoter polymorphism in FGF1 gene increases risk of Alzheimer disease

Alzheimer Disease - Report: Alzheimer disease up in black community, but fewer seek treatment

Alzheimer Disease - Technology to be used in groundbreaking studies of neurological disease

Alzheimer Disease - Tyrosine gated electron transfer toxic mechanism key of Alzheimer beta-amyloid

Alzheimer Disease - World Alzheimer's Day marked with awareness events

Alzheimer Disease - Zinc-binding agonists affect recognition of beta-amyloid epitopes

Anemia - Aranesp approved for extended dosing by European Commission

Angiology - Carotid artery stenting has not proven its safety or efficacy

Angiology - Endarterectomy operative techniques for carotid stenosis are described

Angiology - Lymphangiogenesis can occur in the absence of preexisting vascular beds

Angiology - Novel culture system simulates vascular microenvironment

Angiology - Older subjects exhibited decreased dynamic vasoconstriction

Angiology - Stenting reduces restenosis in small coronary arteries as well as larger ones

Angiology - Stents can be used as adjunct to balloon angioplasty with low complication rates

Angiology - Vasa vasorum architecture is already tree-like in newborn pigs

Angioplasty - CE Mark granted, European launch set for AngioSculpt catheter

Animal Studies - Crossbred mice buoy the study of gene deletion in major organs

Anthrax - Enzyme images reveal secrets of antibiotic resistance, suggest new drug design

Anthrax Vaccine - DNA vaccine protects mice against challenge anthrax STI spores

Anti-Infectives - Fosfomycin inhibits gentamicin-induced lipid peroxidation

Antibiotic Resistance - Antibiotics sold without prescription add to growing resistance problem

Antidepressants - FDA warning on pediatric antidepressants result is significant reduction in use

Antimicrobial - Combination antimicrobials do not reduce mortality in Gram-negative bacteremia

Antimicrobial Resistance - Using antimicrobials to which MRSA strains are resistant perpetuate the outbreak

Antiviral Therapy - The p38 signaling pathway influences the response of hepatitis C to interferon

Aortic Stenosis - Clinical and ECG variables can stratify risk of aortic valve dysfunction

Arrhythmias - Benchmark treatment for heart disorders safe for children of all ages

Arthritis - Artelon CMC-I Spacer cleared by FDA for thumb arthritis

Arthritis - Data presented on anti-inflammatory compounds

Arthritis - Humana members using Vioxx to be notified of Merck recall

Arthritis - Joint implant receives FDA approval

Artificial Heart - Medical device company implants artificial heart as part of CE Mark trial

Aspergillus - Assay to differentiate Aspergillus from other yeasts developed

Assisted Living - Tips offered on selecting living, care arrangements for the aging or ill

Assisted Reproduction - Animal preimplantation development studies will highlight human embryogenesis

Asthma - AT-101 device shows usefulness in experimental asthma, CPR

Asthma - Researchers identify T cell that relieves asthma in mice

Astronomy - Mars orbiter sees rover tracks among thousands of new images

Atherosclerosis - APOA4 T347S variant linked to reduced plasma TAOS in diabetic patients

Atherosclerosis - Gene clusters predict atherosclerosis severity, susceptibility

Atherosclerosis - Inhibition of MAP kinases by antioxidant treatment may be a therapeutic strategy

Atherosclerosis - Results suggest a mechanism for generation of a proatherogenic form of HDL

Atherosclerosis - Results suggest critical involvement of betacellulin in vascular remodeling

Atherosclerosis - Synthetic HDL caused significant regression of coronary atherosclerosis

Atopic Dermatitis - Phase III clinical trial for Desilux begins

Atrial Fibrillation - Antiarrhythmic drugs in atrial fibrillation reviewed

Atrial Fibrillation - Cavo-tricuspid isthmus radiofrequency ablation produces positive outcomes

Atrial Fibrillation - Study investigated trends in atrial fibrillation admissions to U.S. hospitals

Atrial Flutter - Catheter ablation of atrial flutter has high acute efficacy, important risk

Automotive Safety - Detroit Institute of Ophthalmology becomes affiliate of Motor Vehicle Lighting Council

Avian Influenza - Health officials downplay flu fears after death in Thailand

Avian Influenza - Thai bird flu cases raise concern over human transmission

Avian Influenza - Thai bird flu spread is "one-alarm" fire

Awards - $1 million awarded by foundation for healthcare innovations

Awards - Biopharmaceutical firm named one of fastest growing Texas tech companies

Awards - Health products company named among 100 best for working mothers

Awards - Hutchinson, Baucus, McClellan receive awards for support of research on aging

Awards - MIT Magazine of Innovation names scientist Erik Scher a 'Top Young Innovator'

Awards - Pharma firm recognized as a best employer for working mothers

Awards - San Diego Telecom Council names Innovators In Telecommunication

Bacteria - Lipases have limited use in industry due to the cost of their production

Bacterial Infections - Doctors worry as drug-resistant staph infects more healthy people

Bacteriology - LspA1 and LspA2 protein expression by H. ducreyi required for virulence

Bartonella - Population genetic analysis of Bartonella bacilliformis performed

Behcet Disease - Study examines plasma homocysteine concentration and endothelial injury

Benign Prostatic Hyperplasia - Pharma company expands product pipeline, announces study results

Benign Prostatic Hyperplasia - Study shows microwave treatment is as good as open surgery for enlarged prostate

Biochemistry - Estradiol derivatives are versatile reagents for estrogen conjugate preparation

Bioinformatics - Web-based tool sets design vector-based siRNA and siRNA cassettes

Biomarkers - Tumor-associated macrophages and blood factor prognosticate colorectal cancer

Biopharmaceuticals - Centrifugal Bioreactor technology advances into applied development phase

Bioproducts - Production of bioproducts via transgenic animal models may soon be a reality

Biotechnology - Antiemetic action of dexamethasone elucidated

Biotechnology - Business and marketing publication launches

Biotechnology - Effects of tacrine and physostigmine characterized in OB rats

Bioterrorism - Company gets contract for development of new vaccine adjuvants for biodefense

Bioterrorism - Reactive skin decontamination lotion available to U.S. first responder market

Bipolar Disorder - Seroquel more effective than placebo for rapid-cycling bipolar disorder

Bladder Cancer - Enrollment started in non-invasive bladder cancer diagnostic study

Bladder Cancer - Health Canada approves marketing of diagnostic test for bladder cancer

Blood Cleansing - Technology shows potential as countermeasure against bioterrorism

Blood Donations - Groups launch national blood donation campaign

Blood Vessels - Cocaine HCl may inhibit Ca2+ influx and/or intracellular release

Blood Volume - New Jersey-based hospital acquires BVA-100 Blood Volume Analyzer

Body Composition - Polymorphism in glucocorticoid receptor gene linked to good body composition

Bone Grafting - FDA grants approval for new type of bone graft material

Bone Grafting Model - A new bone-graft substitute has osteoinductive and biodegradable properties

Bone Implants - Electrostatic interactions can predict osteoblast attachment to biomaterials

Bone Implants - Hydroxyapatite particles stimulate human monocytes IL-18 production in vitro

Bone Implants - The Ti-15Zr-4Nb-4Ta alloy releases low amounts of metal into rat tibia

Bone Regeneration - Hyaluronic acid in biomatrices protects against common orthopaedic pathogens

Bone Regeneration - Researchers prepare composites that allow for guided bone regeneration

Bone Resorption - Osteoclastic bone resorption stimulated in regucalcin rats with increasing age

Brain Abscess - PPAR-gamma agonist reduces S. aureus-induced microglial activation

Brain Cancer - Cannabinoids have several means for controlling glioma growth

Brain Cancer - MR imaging during brain surgery improves tumor removal

Brain Cancer - Research collaboration aims to identify multi-target drugs for brain cancer

Brain Cancer - Study results offer hope for non-toxic cancer therapy in future

Breast Cancer - Agreement signed for exclusive sale of CT Laser Mammography System in China

Breast Cancer - Blood test provides window into treatment of metastatic cancer

Breast Cancer - Breast MRI gains support as important diagnostic tool

Breast Cancer - CCND1 overexpression common in male patients

Breast Cancer - Combining radiation therapy and tamoxifen helps prevent cancer recurrence

Breast Cancer - Danish HRT users increased risk of cancer with various prognostic indicators

Breast Cancer - Genetic markers of breast tumor estrogen/progesterone receptors identified

Breast Cancer - MR is better than mammography for detecting additional disease in patients

Breast Cancer - MastaScope commercialization expands into Middle-Eastern territories

Breast Cancer - Medical device company received FDA clearance for MammoSite balloon catheter

Breast Cancer - NMP66 breast cancer detection results presented at conference

Breast Cancer - Number of positive sentinel nodes may predict nonsentinel node metastasis

Breast Cancer - Obese women with early stage breast cancer have increased mortality risk

Breast Cancer - Phosphorylation of Y845 mediates binding to the mitochondrial protein

Breast Cancer - Photodynamic agent hypericin has antimetastatic activity in darkness

Breast Cancer - Prediction model breast MRI analysis comparable to expert radiologist

Breast Cancer - Research agreement signed to ID early biomarkers for breast cancer

Breast Cancer - Small proportion of women appear eligible for preventive use of tamoxifen

Breast Cancer - Technology company offers software to ease transition to digital mammography

Breast Cancer - Turkish version of the CHBMS found adequately reliable, valid in Turkish women

Breast Cancer - Types of dietary fatty acids have differing effects on disease risk

Breast Cancer - Wide use of tamoxifen to prevent of breast cancer is unlikely, study indicates

Breast Cancer - Women's critical health issues were focus at seventh annual symposium

Breast Implants - Study finds no connection to development of connective tissue disorders

Brucella - 16S rRNA gene sequencing used for rapid identification of Brucella

Business & Finance - Biopharma company names U.S. VP sales and marketing, provides business update

Business & Finance - Biopharmaceutical company provides financial updates

Business & Finance - Blackstone Group completes major investment in acute care hospitals company

Business & Finance - Companies' stock purchase agreement closes, Dacogen license agreement effective

Business & Finance - Dental-products company raises cash dividend by 14%

Business & Finance - Drug-delivery technology company files for IPO

Business & Finance - Health system releases update in anticipation of actual bond offering

Business & Finance - Medical technology group creates financing arm

Business & Finance - Merrill Lynch adds company to Nanotechnology Index

Business & Finance - Pharmaceutical developer announces positive Q1 financial results

Business & Finance - Prospectus submitted to Polish Securities and Exchange Commission

Business & Finance - RBX maker inks agreements in China, reports record Q3 2004 earnings

Business Solutions - DBOS life sciences application architecture announced

Business Update - Agreement inked to sell NeedleZap in Pakistan and UAE

Business Update - Australian nanotechnology firm spins out diagnostics company

Business Update - Beaumont, Royal Oak opens new inpatient and surgical addition

Business Update - Biopharm company raises $47 million, acquires North American rights to Myocet

Business Update - Biopharmaceutical outsourcing company introduces PAREXEL consulting

Business Update - Cancer Treatment Centers of America expands to east coast

Business Update - Cardinal Health to cut jobs, delays filing annual report again

Business Update - Cardiovascular surgery device manufacturer alters focus, corporate structure

Business Update - CellTracks AutoPrep Systems and CellSpotter Analyzers shipped to Japan

Business Update - Centene buys two profitable health plans

Business Update - Clinical development specialist targeting India as potential growth area

Business Update - Commercial solutions provider enters agreement with pharmaceutical company

Business Update - Cosmetic doctors give TV peers poor ratings, survey shows

Business Update - DTCA, HTZ, and ZT realign under one corporate umbrella

Business Update - Device maker expands into new corporate headquarters

Business Update - Environmental groups, biolab reach settlement agreement

Business Update - Enzyme company announces ISO certification

Business Update - Filtration, separations and purification company founder dies

Business Update - Florida insurer reports increased enrollment

Business Update - Galapagos splits drug-discovery, target-discovery services

Business Update - Grey Healthcare Group wins worldwide business for EXUBERA

Business Update - HealthAmerica/HealthAssurance enter long-term relationship with UPMC

Business Update - Herceptin manufacturing agreement announced

Business Update - IPC expands practice into Las Vegas; names local executive director

Business Update - Invitrogen Corporation announces licensing agreements

Business Update - Lab design company awarded federal contract for hematology, urinalysis inventory

Business Update - Medical device company extents marketing and sales agreement for catheters

Business Update - Medical technology company medical director passes away

Business Update - Memorial Healthcare System expands phone, Internet customer services with Beryl

Business Update - Merge eFilm completes 32 FUSION RIS, PACS, or RIS/PACS customer installations

Business Update - Model N Medicaid Claims Processing announced

Business Update - Mohave Community College gets new health building

Business Update - Northern Colorado to get rehabilitation hospital

Business Update - Nutritional supplements firm purchases additional space

Business Update - Pharmaceutical company reports on potential divestiture of Israeli operations

Business Update - Pharmaceutical company to manufacture Hepalean products for Organon Canada

Business Update - Pharmaceutical conference to discuss issues facing pharma companies

Business Update - Sucanon maker opens Latin American sales office in Mexico City

Business Update - Valley Hospital located in Minneapolis acquired by management company

Business Update - Wesley Medical Center considers opening clinic in Jones County, Mississippi

Cancer - High level of hope positively related to coping in cancer patients

Cancer - Kadian marketed in U.S. for cancer-associated pain

Cancer - Wellness/image booklet helps women undergoing, recovering from cancer therapy

Cancer Diagnosis - New sequence involved in DNA replication timing may aid in cancer detection

Cancer Genetics - Janus kinase 2 modulation in ovarian cancer cells may depend on p53

Cancer Prevention - Actress urges adding cancer screening to women's healthcare

Cancer Prevention - Ban smoking in public places and save lives, says cancer charity

Cancer Prognosis - VEGF signals the probability of breast cancer progression

Cancer Research - Biopharmaceutical company begins phase 1 trial of anticancer agent

Cancer Research - Pharma company announces clinical trial for anticancer compound initiated

Cancer Research - Pharma company releases data from phase 1 for nonHodgkin's B-cell lymphomas

Cancer Research - Pharmaceutical company submits IND for novel anticancer agent Tarvacin

Cancer Research - Positive results reported for Alchemia anticancer compound

Cancer Research - Trials for tumor-blocking pancreatic cancer drug plus chemotherapy promising

Cancer Risk Factor - A gene variant raises liver cancer risk in alcoholic cirrhosis patients

Cancer Screening - Preventive healthcare can overcome barriers of race, socioeconomic status

Cancer Therapeutics - Biopharmaceutical company's therapeutics candidates highlighted at conference

Cancer Therapeutics - Virulizin study results published

Cancer Therapy - Alimta approved in the European Union for two cancer indications

Cancer Therapy - Anti-cancer drug CP-4055 shows promise of efficacy in phase I clinical study

Cancer Therapy - Belgian researchers explore revolutionary approach to angiogenesis

Cancer Therapy - Chemical derived from vitamin E shows early promise as cancer drug

Cancer Therapy - Clinical study of microwave ablation for lung cancer to begin at RI hospital

Cancer Therapy - Clinicians highlight cancer therapy clofarabine at European meetings

Cancer Therapy - Effects of HsEg5 inhibitor monastrol on tumor cells characterized

Cancer Therapy - Efficacy and safety for cancer immunotherapy preclinical results published

Cancer Therapy - Installation of 17 gauge IceRod technology completed at Columbia Presbyterian

Cancer Therapy - National Cancer Institute awards grant for evaluation of mda-7/IL-24

Cancer Therapy - Phase II SBIR grant to be used for next-generation cancer therapeutics

Cancer Therapy - Piperine enhances (-)-epigallocatechin-3-gallate bioavailability in mice

Cancer Therapy - The cytostatic effect of TNP-470 involves cyclin D1

Cancer Treatment - Genetic test signals who will benefit from brain cancer drug

Cancer Treatment - Volunteers give cancer patients free makeovers

Cancer Vaccine - Antitumor responses promoted by bone marrow from immunized donors

Cancer Vaccine - Clinical trial initiated for novel therapeutic DNA cancer vaccine

Cancer Vaccine - Dendritic cell vaccine enhances IFN gene therapy for malignant glioma

Cancer Vaccine - Dendritic cells partially protect against intracerebral viral challenge

Cancer Vaccine - HSP70 expression in apoptotic cells correlates with antitumor efficacy

Cancer Vaccine - Heat shock protein tumor vaccine enhances immune responses

Cancer Vaccine - Poor immunogenicity of tumor antigen due to peptide-MHC-I instability

Cancer Vaccine - Tumor lysate-pulsed cells safe and effective for urological cancers

Cancer Vaccine Development - Killing malignant not normal B cells important for vaccine development

Carcinogenesis - KAT-681 prevents the formation of primary liver cancer in rodents

Cardiac Arrest - Cardiac researchers make surprising find

Cardiac Arrest - FDA OKs defibrillator without prescription

Cardiac Arrest - New system would vastly improve heart defibrillation

Cardiac Disease - Study: Human bone marrow stem cells may effectively treat heart attacks

Cardiac Hypertrophy - A switch to hi-FGF-2 accumulation would exacerbate hypertrophy

Cardiac Hypertrophy - Calcineurin-inhibitory strategies may lead to therapeutic approaches

Cardiac Hypertrophy - Integrin and growth factor signaling pathways may function togther in the heart

Cardiac Hypertrophy - Report describes inflammatory cytokine and renin-angiotensin system interactions

Cardiac Hypertrophy - Researchers describe negative receptors of cardiac hypertrophy

Cardiac Hypertrophy - Signaling pathways have been implicated in cardiac hypertrophy

Cardiac Remodeling - Evidence suggests some Ang II-induced effects are mediated via indirect actions

Cardiac Stents - Clinical trials show millions of U.S. women could benefit from drug-coated stent

Cardiac Surgery - Sleep disturbance occurs before and after cardiac surgery

Cardiology - Acetyl-CoA carboxylation determines malonyl-CoA concentration in the heart

Cardiology - Antibodies to PF4/heparin are a strong predictor of myocardial infarction

Cardiology - Benefits of spironolactone seen in RALES extended to participants not in a trial

Cardiology - Beta-catenin/TCF/Lef transcription is involved in heart cushion formation

Cardiology - Bidirectional modulated parasystole model developed

Cardiology - Carvedilol decreased neurohumoral activation and symptoms

Cardiology - Corin requires frizzled 1 domain and LDLR repeats 1-4 to recognize pro-ANP

Cardiology - Data highlight a mechanism for survival advantage in cardiac fibroblasts

Cardiology - Device closure of patent foramen ovale is a safe, day-case procedure

Cardiology - Effects of a potent mu-opioid receptor agonist are investigated

Cardiology - Methods to measure left ventricular function in diabetes compared

Cardiology - NCX is regulated by Ca2+ during excitation-contraction coupling

Cardiology - Neural crest cells may have role in differentiating cardiac conduction systems

Cardiology - No relation was shown between inflammation and cardioversion outcome

Cardiology - Physicians need additional information on the biological variability of BNP

Cardiology - Proangiogenic gene therapy shows promise for treating cardiovascular disease

Cardiology - Randomized trial of an alternative to heparin in cardiac surgery is encouraging

Cardiology - Researchers review current information on ultrasound thrombolysis

Cardiology - Shorter duration of tirofiban therapy related to impaired myocardial perfusion

Cardiology - Study demonstrates the expression of BNP the rat heart during growth

Cardiology - Study identifies possible gender-related factors in cardiac function

Cardiology - Sympathetic activity could play a role in ventricular tachyarrhythmias in RA

Cardiology - U.S. FDA clears constant voltage EP-4 Stimulator

Cardiomyopathy - Calcineurin-NFAT and MAPK signaling pathways are interdependent

Cardioprotection - Succinate dehydrogenase is a component of mitoKATP as part of super-complex

Cardiopulmonary Bypass - Surface-warming device enables safe limited rewarming

Cardiovascular Care - Tiny implant promises to prevent strokes caused by irregular heartbeat

Cardiovascular Devices - Bone cutter useful for removal of pulse generator header leads

Cardiovascular Devices - Modified ICD arrhythmia detection algorithm has improved specificity

Cardiovascular Devices - Pacemaker upgrade feasible in young patients

Cardiovascular Disease - Animal models provide insights into vascular complications of diabetes

Cardiovascular Disease - Positive phase I results announced for intravenous formulation of MC-1

Cell Biology - ATF4 is translationally regulated by hypoxic stress

Cell Biology - Culture conditions strongly influence gene expression in senescent cells

Cell Biology - GMAP-210 activity required for Golgi ribbon formation

Cell Biology - Molecular motor implicated in tissue remodeling

Cell Biology - NOBOX gene expression is crucial to postnatal follicle formation

Cell Biology - The new gene fad158 regulates fat cell differentiation

Cell Research - IMM-targeted antioxidants may be beneficial in treatment of aging

Cell Research - Shear force-dependent inhibition provides insights into vasoprotective effects

Central Nervous System - Biotechnology company announces partnership with ImClone Systems

Central Nervous System - Central nervous system disorder therapy developer names CEO

Central Nervous System - Pharma company announces acquisition of rights to commercialize tetrabenazine

Central Nervous System - VEGF-A stabilizes neovascularization in the murine brain

Cerebellar Disease - Conditioned postural reflex is difficult for cerebellar patients

Cerebrovascular Autoregulation - Two-breath technique detected dependence of the CO2 response on PCO2

Cervical Cancer - ACOG clarifies recommendations on screening in adolescents

Cervical Cancer - Chemotherapeutic potential of plumbagin investigated

Cervical Cancer - PCR more HPV-sensitive than signal amplified in situ hybridization

Cervical Cancer - Surgical technique described for locally progressive advanced disease

Cervical Laminoplasty - A titanium plate can maintain canal expansion in cervical laminoplasty

Chagas Disease - Genes involved in cardiac mitochondrial dysfunction identified

Chagas Disease - High-resolution satellite imagery assists hunt for infectious "kissing bugs"

Chemoresistance - Upregulation of BH3-only protein circumvents melanoma drug resistance

Chemotherapy - Scopadulciol-related molecules are weak mediators of cancer gene therapy

Child Abuse - Japanese child abuse cases soar to record high

Childhood Immunizations - Researchers and policy makers asked to "fast track" access to childhood vaccines

Childhood Obesity - Adiponectin level increases after weight loss in obese children

Childhood Obesity - Serum tumor necrosis factor-alpha levels higher in obese adolescents

Childhood Obesity - Shape It Up program teaches New Jersey children about risks of obesity

Chiropractic Care - Aspen DC elected president of the Colorado Chiropractic Association

Chlamydia - Women in mid-to-late teens 43% more likely to test positive for Chlamydia

Chorioretinopathy -  H. pylori may be related to idiopathic central serous chorioretinopathy

Chronic Heart Failure - Low-frequency power may aid in stratifying the risk of sudden death

Chronic Heart Failure - Muscle chemoreflex inputs to cardiovascular control need multiple measurements

Chronic Hepatitis B - The COBAS AM assay is better suited for detecting low hepatitis B virus levels

Chronic Obstructive Pulmonary Disease - Deletion allele is associated with quadriceps strength in obstructive disease

Clinical Trials - Advice on how to find trials of experimental drugs

Clinical Trials - Registry push could ease patients' hunt for drug

Coagulation Therapy - Heparin effect can be quantified by endogenous thrombin potential

Cognition - Gender plays no role in the association between the 5HTT gene and neuroticism

Collaboration - M.D. Anderson, MEMS join to develop portable bio-chemical analyzers

Collaborations - Agreement signed for development of generic drugs

Collaborations - Companies announce collaboration agreement on PDE4 inhibitor for asthma, COPD

Collaborations - Deal signed to study genetic variations associated with myoclonic epilepsy

Collaborations - Deal signed with Korean partners for TB drug development

Collaborations - Elinc enters strategic collaboration with image-management company

Collaborations - Fletcher/CSI and Tracer Analytics form strategic partnership

Collaborations - Genomics companies collaborate to deliver systems biology tools

Collaborations - German, French companies collaborate in the field of infectious diseases

Collaborations - Licensing agreement signed for pimecrolimus for drug-eluting stents

Collaborations - Low-carb diet firm joins forces with educators to combat pediatric obesity

Collaborations - Merck partnering with Nastech on nasal spray obesity drug

Collaborations - Nanobody maker, Genencor form oncology alliance

Collaborations - Promising anti-obesity drug leads acquired by Biovitrum

Collaborations - Rights granted to more than 80 new patents, applications from Caltech

Collaborations - Therapeutic antibody deal signed to develop gastrointestinal cancer therapies

Collaborations - Vendor program partners with pharmaceutical company

Colon & Breast Cancer - New assay can measure capecitabine and its metabolites in plasma

Colon Cancer - Eloxatin to receive expanded indication in Europe for early-stage colon cancer

Colon Cancer - Expression of IAP family proteins is associated with colon cancer

Colorectal Cancer - Acne-like rash linked to effectiveness of new targeted cancer treatment

Colorectal Cancer - Cancer screening tools widely underused

Colorectal Cancer - Prostaglandin EP receptors targets for colorectal cancer treatment/prevention

Complementary and Alternative Medicine - Caraway and caper are potential anti-hyperglycemic plants for diabetes

Complementary and Alternative Medicine - New Mexico employers can enrich health benefits through complementary coverages

Complementary and Alternative Medicine - Vitamin supplements no benefit against gastro-intestinal cancer

Compliance - Respiratory-products maker receives quality manufacturing systems certification

Computer Vision Syndrome - Computer keyboards offer relief from computer eye strain in the workplace

Contraception - Efficacy of anti-fertility vaccine compared in male animals

Contraception - FV Leiden polymorphism probably doesn't contraindicate birth control pill

Cord Blood - New cord blood somatic SCs has intrinsic pluripotent differentiation potential

Cord Blood - Umbilical cord blood is a legitimate source of mesenchymal stem cells

Coronary Artery Bypass Grafting - Expanded PTFE surgical membrane does not increase mediastinitis risk

Coronary Artery Bypass Grafting - Hematological response in off-pump CABG characterized

Coronary Artery Disease - Metricath System to be distributed in six European countries

Coronary Vasodilation - Coronary vasodilation induced by amiodarone highly depends on nitric oxide

Cosmetic Surgery - Many American adults are having some type of cosmetic surgery

Creutzfeldt-Jakob Disease - Causal link behind BSE and Creutzfeldt-Jakob disease has scientific basis

Creutzfeldt-Jakob Disease - Large-scale tonsilectomy study would quantify U.K. CJD prevalence

Critical Care Medicine - Closed tracheal suctioning system lowers gastric-bronchial cross-contamination

Critical Care Medicine - Effects of laryngoscopy and tracheal intubation on pulse pressure determined

Critical Care Medicine - Xenon improves recovery from myocardial stunning in dogs

Croup - Study suggests steroid for kids with croup

Cryptosporidiosis - Cryptosporidiosis occurrence found in patients in hospital in Brazil

Cystic Fibrosis - CF-KO murine model useful for study of altered drug clearance

Cystic Fibrosis - Principal investigator announced for phase I trials in cystic fibrosis

Cystic Fibrosis - Temporal temperature gradient gel electrophoresis detects CFTF gene mutations

Cytology - Study: Nasal respiratory epithelium is an ovarian steroid target

Cytomegalovirus Vaccine - Cytomegalovirus immune evasion proteins do not prevent T-cell response

DNA Research - Solid-phase preparation of DNA oligonucleotides described

DNA Research - Suppression of MCM10 and TopBP1 involved in UV-induced DNA damage

DNA Vaccine - TLR9- and TLR9+ mice display similar immune responses to DNA vaccine

Deep Vein Thrombosis - SonoLysis phase I/II clinical trial initiated in deep vein thrombosis

Dementia - Regular physical activity associated with better mental function in older women

Dementia - Walking associated with reduced risk of dementia in older men

Dengue Virus Vaccine - Homotypic interaction domain of core protein of dengue virus identified

Dental Implants - Researchers verify a functionally graded interphase between cementum and dentin

Dentistry - Research team to study whether cleaning teeth reduces risk of heart disease

Depression - Approval granted to market citalopram in Spain

Depression - E.U. scientific committee recommends approval of duloxetine

Depression - FDA to study suicide risks in adults

Depression - Genaissan acquires rights to vilazodone antidepressant

Dermatology - Intense pulsed light safe and effective for permanent hair removal

Dermatology - Skin care company expands Asia-Pacific distribution

Dermatology - VEGF-A signals may encourage persistent inflammation

Di-Peptide Manufacturing - Novel manufacturing process developed for di-peptides

Diabetes - Economic analysis indicates use of Diachrome for diabetes could offer savings

Diabetes - MedicAlert and ADA to increase informational access for people with diabetes

Diabetes - Medical device company expands options for diabetic peripheral neuropathy

Diabetes - President of India inaugurates new biotech park

Diabetes Genomics and Genetics - Germline mosaicism for KCNJ11 gene mutation linked to neonatal diabetes

Diabetes Insipidus - Features of patients with congenital diabetes insipidus described

Diabetes Pathogenesis - Effects of thioacetamide on pancreatic islet B-cell function described

Diabetes Pathogenesis - Hexoses exert differential effects on insulin and glucagon release

Diabetes Pathogenesis - Mice expressing TNDM locus have impaired glucose homeostasis

Diabetes Pathogenesis - New animal model for studying diabetes described

Diabetes Prevention - Prevention of type 1 diabetes reviewed

Diabetes Risk Factor - Possible mechanism of arsenic-induced diabetes proposed

Diabetes Risk Factor - Type 1 diabetes risk defined by leukocyte antigen class II genotype

Diabetes Survival and Mortality - Kidney disease increases mortality risks in patient with diabetes

Diabetes Therapy - Advances in insulin sensitizers reviewed

Diabetes Therapy - Complete response submitted to FDA for Symlin for glucose control

Diabetes Therapy - Fibrates in metabolic syndrome and diabetes reviewed

Diabetes Therapy - Glucocorticoid antagonists offer therapy option for type 2 diabetes

Diabetes Therapy - Glycemic control in patients at community health centers examined

Diabetes Therapy - Telmisartan improves plasma lipids in hypertensive, diabetic patients

Diabetic Glomerular Hypertrophy - No protective role found for estrogen receptor alpha in diabetic nephropathy

Diabetic Nephropathy - Adiponectin levels affected by renal function and diabetes duration

Diabetic Nephropathy - Diabetes is major cause of kidney disease in China

Diabetic Retinopathy - Glutamate receptor expression in retina diabetic rats examined

Diagnostic Imaging - Positron emission tomography grants a noninvasive look at transgene activity

Diagnostics - A new, rapid immunochromatographic assay detects botulinum neurotoxin type B

Diagnostics - An HPLC method can detect lisinopril in human plasma and urine

Diagnostics - An automated method quantitatively determines SCH 201781 in human plasma

Diagnostics - Automated method can determine piperaquine in capillary blood

Diagnostics - Buccal cells from mouthwash are a source of mRNA for molecular analysis

Diagnostics - Cancer diagnostics company launches automated staining instrument

Diagnostics - Company introduces new FDA-approved and CE-marked ELISA product line

Diagnostics - DNA microarray method to identify bacteria in fecal samples developed

Diagnostics - Diagnostics tests measure metastatic breast cancer circulating tumor cells

Diagnostics - Efficient magnetic cell labeling for cellular MRI accomplished

Diagnostics - Gene-specific PCR provides rapid detection of E. coli clonal group

Diagnostics - Method can measure clozapine and its metabolites in schizophrenics' plasma

Diagnostics - Nanoparticles serve as fluorescence probes in the determination of nucleic acids

Diagnostics - Near-infrared instruments developer's product launched by licensee

Diagnostics - Novel rapid PCR field assay detects E. coli O157:H7 and L. monocytogenes

Diagnostics - Novel solution can eliminate background in film-based applications

Diagnostics - PCR assay can identify some E. coli strains in food and water

Diagnostics - Real-time PCR is standard for quantitative CMV viremia assessment in transplants

Diagnostics - Shipment begins of CLIA-waived AST test for monitoring drugs' liver effects

Diagnostics - TaqMan hepatitis C virus RNA analyte-specific reagent has wide-ranging uses

Diagnostics - Telemedicine company extends ECG contract with Nevada corrections department

Diagnostics - Variables affect substance P measurement in heart, lung, and skin tissue

Diet & Nutrition - CER scores associated with body fatness, not other measures of dieting in women

Diet & Nutrition - Salad before a meal helps women reduce calorie intake

Diet & Nutrition - Unrecognized iron deficiency can impair immunity in older women

Diet Trends - Research confirms early theories of Dr. Robert C. Atkins

Diet and Nutrition - Folate regulates the way Hox genes influence the skeletal phenotype

Diet and Nutrition - High-fat diet affects protein expression in muscle, adipose tissue, and liver

Diet and Nutrition - Marriott offers "Fit for You" program for diverse dietary lifestyles, needs

Diphtheria Vaccine - Diptheria toxin expressed in Streptococcus fails to neutralize toxicity

Disease Associations - Leprosy susceptibility and Parkinson disease share similar genomics

Disease Management - GHI introduces diabetes-management initiative: Bingo

Disease Management - Pharmaceutical company's disease management programs receive NCQA certification

Disease Prevention - Antiretroviral therapy of HIV+ moms who breastfeed may protect infants

Domestic Abuse - Elder abuse a hidden tragedy

Dracunculiasis - Eradication program has almost wiped out parasitic disease

Drug Benefits - CMS extends helping hand to low-income beneficiaries

Drug Delivery - Certain dendrimers based on melamine may be candidate vehicles for drug delivery

Drug Delivery - Company successfully completes second phase of topical ENT-103 formulation

Drug Delivery - FDA grants Vitrase 3-year market exclusivity

Drug Delivery - Nanoparticle-containing adriamycin increases distribution of the drug

Drug Delivery - Optimal coating agents determined for oral drug delivery system

Drug Delivery - Pfizer purchases Meridica Limited from consulting company

Drug Delivery - Pharma company initiates human study of Xanax lingual spray

Drug Delivery - Phase III trials for Micropump formulation of a GlaxoSmithKline product begin

Drug Development -  Plasmodium vivax hexose transporter characterized

Drug Development - Amiodarone does not affect ximelagatran pharmacokinetics

Drug Development - Anti-VEGF antibody and interleukin-12 staunch tumor growth in murine models

Drug Development - Arundic acid shows promise for treatment of stroke

Drug Development - Biopharmaceuticals company updates anidulafungin regulatory status

Drug Development - Clinical trials involving children are needed

Drug Development - Companies collaborate to develop, market genomic purification applications

Drug Development - Companies enter new marketing agreement for Vitrase

Drug Development - Compound eradicates brain tumor in preclinical cancer model

Drug Development - Confocal and fluorescence microscopy useful for study of liquid bioadhesion

Drug Development - Flavin-dependent thymidylate synthase activity characterized

Drug Development - Grape-derived alkaloids have potent antioxidant activity

Drug Development - Group submits formal input to FDA on Critical Path Initiative

Drug Development - HTG's gene-expression technology to support company's pharmaceutical research

Drug Development - LC/MALDI assay suitable for membrane proteome analysis

Drug Development - Novel Akt inhibitors reduce drug resistance in leukemic cells

Drug Development - Phosphatidylinositol ether lipid analogues induce apoptosis in cancer cells

Drug Development - Positive results in preliminary phase 3 rheumatoid arthritis drug trial reported

Drug Development - Revaprazan hydrochloride safe and effective for gastric acid inhibition

Drug Development - Software can help with decision-making in the biopharmaceutical industry

Drug Development - Study of drug for advanced pancreatic cancer shows significant survival benefit

Drug Development - Using dried blood spots in discovery stage pharmacokinetics is feasible

Drug Development - Vanilla may have a future as a sickle cell treatment, research shows

Drug Discovery - Biopharmaceutical company completes second performance milestone

Drug Discovery - Collaboration to discover, develop up to 50 antibody products over 10 years

Drug Discovery - Inexpensive thermal shift assay developed

Drug Discovery - NIH awards grant for development of novel antibacterials

Drug Discovery - Research organization obtains nonexclusive license to ProxiQuant technology

Drug Discovery - Saline perfusion not needed for rat brain penetration studies

Drug Discovery - Shipments started of a new instrument platform for flow cytometry analysis

Drug Discovery - Software provider to complete release of modeling, simulation tools for Linux

Drug Discovery - Study of application of TRAP drug discovery technology published

Drug Importation - Kentucky could save on Canada Drugs

Drug Importation - Study estimates large job loss in Michigan if drug importation is adopted

Drug Monitoring - Non-invasive phenytoin monitoring feasible with reverse iontophoresis

Drug Resistance - HIV-1 K103N mutation present in antiretroviral therapy-naive patients

Drug Resistance - Higher amprenavir plasma minimal concentration associated with lower resistance

Drug Resistance - Increased drug resistance reported in Streptococcus pneumoniae isolates

Drug Resistance - Publication challenges clinical significance of aspirin resistance

Drug Safety - Intelligence initiative launched to combat illegal Internet pharmacies

Drug Therapy - Medication errors frequently occur with anticoagulant therapy in hospitals

Drug resistance - DNA microarray identifies beta-lactamases that confer antimicrobial resistance

Earth Science - Scientists report increased thinning of West Antarctic glaciers

Eating Disorders - Neuroticism, BMI, gender, and age factors for ED in physically active students

Eating Disorders - Officials see more eating disorders in men

Eating Disorders - Researchers conducting study of anorexia treatments

Echocardiography - Combined probe offers effective cardioversion with low energy levels

Echocardiography - Consider gender and racial differences in BP response in dobutamine testing

Echocardiography - Myocardial performance index can reliably diagnose RV infarction

Echocardiography - New endocardial boundary detector overcomes problems in clinical applications

Echocardiography - Patients with 'lone' atrial fibrillation may have atrial abnormalities

Echocardiography - TEE transducer transmits at a lower frequency and receives a second frequency

Eczema - Phase I/II trials to begin for NF-KB Decoy in eczema

Edema - Studies: ProAlgaZyme reduces edema in lab animals

Electrocardiography - Method improves denoising in ECG signals

Electronic Medical Records - Buyer's guide helps medical practices evaluate electronic medical record systems

Electronic Medical Records - Duke University Health System completes first phase of wireless access

Electronic Medical Records - Galvanon and Kryptiq form alliance to unite self-service solutions with EMR

Electronic Medical Records - Study finds point of care technology plays key role in U.S. health care system

Embryonic Research - Methylation fluctuations are critical to vertebrate development

Emergency Medicine - Obese trauma patients more likely to die of their injuries

Employee Health - Freddie Mac opens free, on-site health center for employees

Encephalomyelitis - Amino acid copolymers amerliorate encephalomyelitis

Encephalomyelitis - T cells specific for onconeuronal antigen mediate encephalomyelitis

Endocrinology - Cre recombinase transgenic mice will expedite human adult thyroid analysis

Endocrinology - Estrogen-responsive genes identified in novel pituitary cell line

Endocrinology - Maternal hypo- or hyperthyroidism may cause infants' impaired vision processing

Endocrinology - Treating even mild hyperthyroidism makes for stronger bones, muscles in women

Endometriosis - Report: Disease's "market" will be affected by drug patent expirations

Enteric Disease - A mutation assay detects ciprofloxacin-resistant Campylobacter jejuni

Enterobacter Outbreak - Source of Enterobacter aerogenes outbreak in pediatric unit not elucidated

Environmental Health - Effects of Cold War nuclear tests on Idaho residents presented to panel

Environmental Health - Fungal burden monitored for 2 years in a Florentine hematology ward

Environmental Health - Genotoxic effects of N-nitrosomorpholine clarified

Environmental Health - Novel LC/MS assay used to evaluate CYP-mediated DCE metabolism

Environmental Health - Risk assessment strategies for drugs in aquatic environments compared

Environmental Toxins - Children's exposure to air pollutants most influenced by air in the home

Environmental Toxins - Children's exposure to common plasticizers linked to asthma, allergies

Environmental Toxins - Cigarette smoke causes breaks in DNA and defects to a cell's chromosomes

Environmental Toxins - Genetic mutations linked to the practice of burning coal in homes in China

Environmental Toxins - Study: sprawl linked to chronic ailments

Enzymology - Macrophages generate cytokines that stimulate breast cancer invasion

Enzymology - The hepatitis C virus NS5B C-21 domain has multifunctional properties

Epidemiology - Socio-biological parameters of pregnant, Maltese drug abusers assessed

Epilepsy - Childhood epilepsy diagnostic licensed for marketing in North America, Japan

Epilepsy - Remote video camera system used for epilepsy monitoring

Epilepsy - Valacyclovir reduces seizure susceptibility in HSV-1-infected mice

Erectile Dysfunction - Erectile function in diabetes not linked to aminoguanidine timing

Ethical Issues - U.K. council ponders issues surrounding prolonging life of ill fetuses, newborn

Ethics - Ethics, candor seen as key elements to rebuilding public trust in healthcare

Ethics - Future of cosmetic neurology debated

Exercise - Even low fitness level reduces cardiovascular morbidity and mortality

Exercise - Exercise normalizes overexpression of TNF-alpha in knockout mice

Exercise - Role of oxygen in phosphocreatine onset kinetics determined

Eye Health - Study reveals 90% of children prefer photochromic eyeglasses

Eye Health - Vision care company receives fourth patent of 2004

Facilities - Children's, Univ. Pennsylvania Medical Center agree on costs of new complex

Fall Prevention - Ingen Technologies, Medicore sign marketing contract for Secure Balance program

Fibromyalgia - Study supports hypothesis that FM is a depression spectrum disorder

Finance - Alliance HealthCard announces record third quarter profit

Finance - American Stock Exchange lists common stock of medical device firm

Finance - American stock exchange lists common stock of drug delivery company

Finance - Australian biotech firm raises $4M

Finance - Australian oncology firm lists on Frankfurt exchange

Finance - Biopharm company exchanges series A warrants, terminates rights agreement

Finance - Biotech company issues revised financial guidance

Finance - Biotech firm delays sale-leaseback of Baltimore facility

Finance - Biotechnology company announces exchange price in stock transaction

Finance - Contract clinical research organization reports first quarter financial results

Finance - DSM Venturing invests in company that develops genetic tests

Finance - Dental implants company secures $12.5M in equity financing

Finance - Device company revises guidance for third quarter and remainder of 2004

Finance - Device firm reports 18% increase in sales

Finance - Device maker reports 67% increase in second quarter earnings per share

Finance - Diagnostics company's common stock to continue Nasdaq listing

Finance - Diagnostics maker reports 16th consecutive quarterly dividend

Finance - Doctors' earnings remain flat, lag behind cost of living increases, survey shows

Finance - Early stage life sciences fund raises $26M

Finance - Financial analyses, intelligence company for life science launches LSI 100 Index

Finance - Forstmann prices secondary offering of remaining Community Health Systems shares

Finance - Frovatriptan maker reports interim results for the 6 months ended 30 June 2004

Finance - Genomics company ends $4.1 million second round of financing to grow U.S. market

Finance - Health Care REIT, Inc., issues $50 million in senior unsecured notes

Finance - Health-products maker declares $2 special, 40% increase in quarterly, dividend

Finance - Hospital group completes 9-3/4% tender offer for senior subordinated notes

Finance - Hospital system announces fiscal 2004 annual and fourth quarter results

Finance - Indiana life sciences gets $1.2M grant for workforce training

Finance - Liquid-bandage maker revises 2004 financial outlook

Finance - Medical device company raises $16 million in series C financing

Finance - Medical devices maker closes series D financing, reports significant milestones

Finance - Medical equipment company announces revenues of $3,274,281 in first half of FY04

Finance - Medical instruments manufacturer announces record first quarter revenue

Finance - Medical products supplier declares quarterly dividend

Finance - Medical technology company reports record third quarter net sales

Finance - Oncology company files registration statement with SEC

Finance - Pharmaceutical company announces pricing of $500 million offering

Finance - Pharmaceutical company reports increases in revenue, net income

Finance - Pharmaceutical firm approved for listing on AMEX

Finance - Pharmaceuticals company announces closing of convertible note exchange

Finance - Polymer technology company announces record revenues

Finance - Provider to industry revises third and fourth quarter outlook

Finance - Supplier to life sciences lowers expectations for 2004, acts on compliance

Finance - U.S. government to invest up to $35 million in interdisciplinary PhD programs

Finance - UT Southwestern receives $1.78 million grant for obesity research

Finance - VEGF-2-focused company completes private placement and closing on loan facility

Finance - Wound care company focuses on maximizing revenues

Fitness - Calcium intake and vigorous daily exercise necessary to build bone density

Fitness - Promoting walking, cycling as an alternative to using cars: what works?

Fitness & Wellness - After exporting organic products abroad, Mexico spreads healthy eating at home

Fitness & Wellness - As waistlines expand, fat-fighting efforts increase

Fitness & Wellness - Health benefits, medical cost savings associated with some dietary supplements

Fitness & Wellness - Multivitamin smoothie introduced by franchising company

Fitness & Wellness - Ohio stand teens navigate corn maze to curb tobacco use among peers, others

Fitness & Wellness - Organic milk may be a way to save dairy farms

Fitness & Wellness - Schools add a dash of nutrition to lunch

Fitness & Wellness - Schools weigh changes to combat obesity

Fitness & Wellness - Seniors taking up mind-body exercise classes like tai chi, yoga

Fitness & Wellness - Suburan sprawl linked to chronic ailments; may be lack of opportunities to walk

Fitness & Wellness - Vitamin B12 taken nasally can stave off anemia after weight reduction surgery

Food Allergy - Epicutaneous exposure to food may induce systemic immunoglobulin E sensitization

Food Safety - Federal agencies sign agreement with NASDA to make food supply more secure

Food Safety - Seneca Foods recalling canned beets due to contamination worries

Food-Borne Illness -  Salmonella and E. coli may grow in oranges meant for juice

Food-Borne Illness - Phage spraying optimized to reduce Listeria on honeydew melon

Food-Borne Illness - Sulfite recalls and reported adverse events reviewed

Foot-and-Mouth Disease - U.K. management of foot-and-mouth disease outbreak in 2001 still controversial

Fragile X Syndrome - Non-invasive hair test suitable for FRAXA diagnosis

Funding - New Mexico gets grant to offset health costs

Funding - University of Wyoming gets $13M from U.S. National Institutes of Health

Fundraising - Communications group sponsors Portland's Susan G. Komen Race for the Cure

Fundraising - Food retailer raises $2.3 million for Muscular Dystrophy Association campaign

GB Virus C - GB virus C viremia associated with increased quality of life in HIV infection

Gastric Cancer - Curing Helicobacter pylori infection does not prevent all gastric cancers

Gastric Cancer - Study results validate ZNRD1 as a potential therapeutic target in gastric cancer

Gastric Ulcer - Pharma company files IND with FDA to initiate trial for chronic pressure ulcers

Gastroenterology - Wound repair and angiogenesis is altered in inflammatory bowel disease

Gastrointestinal Disease - Interleukin-10 gene therapy ameliorates colitis in murine models

Gender-Based Medicine - Men, women more different than thought

Gene Analysis - Whole genome amplification secures enough DNA for typing HLA variants

Gene Inhibition - Synthetic curcumin analogs curtail genes related to angiogenesis

Gene Profiling - Scientists decipher genome of ancient pathogen used in biological weapons

Gene Suppression - Small interfering RNA gene silencing is conserved in mammalian cells

Gene Transfer - Immunoporation provides stable cell line transfection

Gene Transfer - SV40 pseudovirions are efficient gene vectors

Generic Drugs - Court vacates stay on gabapentin capsules launch

Generic Drugs - Pharma company approved to manufacture loratadine and pseudoephedrine tablets

Generic Drugs - Pharma company receives tentative approval of generic Ultracet

Genetic Disorder - A sibling with UROS homozygosity for erythropoietic porphyria remains healthy

Genetic Testing - Far more men than women favor routine paternity testing at birth

Genetics - Businessman forms self-titled genetic institute

Genetics - Cytidine deaminase recruited to S regions by the transcriptional machinery

Genetics - Researchers find soybean plant that lacks allergy-causing protein

Genomics - A new HCV beacon assay more accurately monitors chronic hepatitis C patients

Genomics - Agreement signed offering U.S. NIH access to genomics software

Genomics - DNA sequencing software developer releases updates

Genomics - Gene-synthesis company awarded NIH-NHGRI gene-synthesis grant

Genomics - Genome company awarded National Human Genome Research Institute grant

Genomics - Inaccurate probes hamper the accuracy of microarray-based gene analysis

Genomics - Sprouty1 may serve as an intrinsic mediator governing ventricular remodeling

Genomics and Genetics - Comprehensive mapping of cartilage transcripts to human genome achieved

Genomics and Genetics - Novel potentially defective CYP2C9 alleles identified

Genomics and Genetics - Pooled DNA suitable for microarray genotyping

Genomics and Genetics - Regression method used to identify cis-regulatory motifs

Geriatrics - Health officials halt admissions to nursing home after finding deficiencies

Geriatrics - Legal issues related to practice of anti-aging medicine reviewed

Geriatrics - Nursing home operator pulls out of Oklahoma

Geriatrics - Three charged in connection with death at Rhode Island nursing home

Glaucoma - Approvable letter issued for Extravan

Glycohemoglobin - Worldwide standardization of HbA1c determination promoted

Graft-Versus-Host Disease - Infliximab well tolerated/effective for steroid-resistant acute GVHD treatment

Graft-Versus-Host Disease - Monocyte/macrophage dysfunction has major role in pathophysiology of GvHD

Grants - Federal grant will increase testing of newborns in U.S. heartland

Grants - U.S. Health and Human Services Secretary announces $35.7M in health grants

Gulf War Syndrome - Veterans have damage in specific, primitive portion of nervous system

Gynecologic Cancer - Data gathered and reported during gynecologic cancer awareness month

Gynecologic Cancers - Concurrent ovarian and endometrial cancers highlight diagnostic difficulties

Gynecologic Cancers - Study validates Sexual function-Vaginal changes Questionnaire

Gynecology - Double-modified adenovirus transfers genes to cervical cancer in vivo

HIPAA - Notice of HIPAA elimination of grace period for updating codes discussed

HIV Diagnostics - MiraWell Rapid HIV Tests shipped to Caribbean distributor

HIV Diagnostics - VScan HIV rapid test kits shipped to Indonesia

HIV/AIDS - Nonexclusive license relating to immunoassay for the detection of HIV announced

HIV/AIDS Coinfection - High frequency of HIV/HBV coinfection in Cote d'Ivoire

HIV/AIDS Epidemiology - Act now to avoid a major HIV/AIDS epidemic in Western Pacific region, WHO says

HIV/AIDS Epidemiology - HIV-1 CTL escape mutants frequently transmitted in HLA-A24-positive Japanese

HIV/AIDS Epidemiology - Population genetics of HIV-1 group O estimates radiation from 1890 to 1940

HIV/AIDS Gene Therapy - Hammerhead and hairpin ribozymes effective against various HIV-1 target sites

HIV/AIDS Prevention - Bono urges British lawmakers to fight AIDS, poverty in Africa

HIV/AIDS Prevention - New Mexico shifts AIDS education

HIV/AIDS Prevention - Pope again stresses chastity to fight AIDS' spread

HIV/AIDS Prevention - Texas city sues prostitute to curb HIV infections

HIV/AIDS Prognostics - Total lymphocyte count not a substitute for CD4 cell count in HIV management

HIV/AIDS Research - APOBEC3G encapsidated through direct interaction with HIV-1 Gag

HIV/AIDS Research - Apolipoprotein E has antioxidant properties against HIV-1 Tat-induced toxicity

HIV/AIDS Research - Backbone dynamics of HIV-1 RT RNase H domain similar under all conditions

HIV/AIDS Research - Cleavage of HIV-1 GagPol precursor by activated protease occurs intramolecularly

HIV/AIDS Research - ERK-2 regulates viral assembly and release by phosphorylating HIV-1 p6(Gag)

HIV/AIDS Research - HIV mRNA nuclear export elements regulate protein function and virion assembly

HIV/AIDS Research - HIV proviruses genetically diverse within an infected cell

HIV/AIDS Research - HIV-1-specific CD4+ T cells directly contribute to antiviral immunity

HIV/AIDS Research - Mitochondrial DNA not a marker of toxicity in HAART-treated patients

HIV/AIDS Research - NHEJ DNA repair pathway has role in completion of HIV-1 DNA integration process

HIV/AIDS Research - Packaging HIV vectors with FIV is viable alternative to HIV structural proteins

HIV/AIDS Research - RNA interference against PARP-1 efficiently suppresses HIV-1 replication

HIV/AIDS Research - Single-LTR HIV-1 vector is optimized for functional genomics applications

HIV/AIDS Research - Unpaired nucleotides facilitate HIV-1 RT displacement synthesis via duplex RNA

HIV/AIDS Screening - South African sales of new rapid result HIV tests begin

HIV/AIDS Therapy - Agreement between Samoa and UC Berkeley could help search for AIDS cure

HIV/AIDS Therapy - Amprenavir-ritonavir is a viable option for twice-daily or daily HIV therapy

HIV/AIDS Therapy - Drug resistance mutations in HIV-1 RT increase template-switching frequency

HIV/AIDS Therapy - HIV-1 viral fitness targeted as a therapeutic strategy

HIV/AIDS Therapy - Lopinavir/ritonavir plus phenytoin results in a two-way drug interaction

HIV/AIDS Therapy - Phenotypic susceptibility predictive of HIV-1 RNA response in PI users

HIV/AIDS Therapy - Scientists successfully target key HIV protein

HIV/AIDS Therapy - Spirodiketopiperazine-based CCR5 inhibitor active against HIV-1

HIV/AIDS Transmission - N-9-containing lubricants may enhance rectal transmission of HIV and other STDs

HIV/AIDS Treatment - Few patients have good virological response after 2 years treatment interruption

HIV/AIDS Treatment - HIV vaccine trial moving to enroll last cohort of volunteers

HIV/AIDS Treatment - Therapeutic drug monitoring useful tool in treatment of HIV-1-infected children

HIV/AIDS-Associated Cancer - Cancer registry data useful resource for monitoring HIV-associated cancers

HIV/AIDS-Associated Insulin Resistance - Novel insulin receptor activator prevents PI-induced insulin resistance

HIV/AIDS-Associated Lymphoma - T- and B-cell lymphoma demographics/immunology in HIV-infection characterized

Hantavirus - Hantavirus outbreak in Brazil via occupational exposure to infected rodents

Head and Neck Cancer - Amyloid precursor protein is a prognostic marker for oral carcinogenesis

Head and Neck Cancer - Curcumin regulates nuclear factor kappa B to suppress cancer cell growth

Head and Neck Cancer - History of smoking significantly reduces survival in cancer patients

Head and Neck Cancer - Immunological aspects of head and neck cancer reviewed

Head and Neck Cancer - Nitric oxide accelerates regression in head and neck cancer

Health Care - Children's Medical Center of Central Texas receives $25M matching grant

Health Care - PacifiCare expands its Secure Horizons Medicare+Choice plan in Colorado

Health Education - Hospitals group launches Spanish-language site for pregnant women, new mothers

Health Management - Blue Cross launches comprehensive health management program

Health Savings Accounts - Ascent Assurance to offer HSA compatible high deductible health plans

Healthcare & Politics - Washington medical group explains differences between healthcare initiatives

Healthcare Access - California state prisons should mirror federal prison healthcare, senators say

Healthcare Access - Drug shortages negatively affecting patient safety, costs of care

Healthcare Access - Drugstores look to expand consultations, and charge for them

Healthcare Access - Home healthcare services company accredited by community health program

Healthcare Access - Innoviant develops specialty pharmacy network for members

Healthcare Access - Twenty of Baltimore's 39 high schools lack nurses

Healthcare Costs - As health premiums keep soaring, smaller firms try new approaches

Healthcare Coverage - Advocates want new Connecticut healthcare program delayed again

Healthcare Coverage - Clinic celebrates 20 years of local Alaska Native health service

Healthcare Coverage - Consumer group says Americans worse off in terms of healthcare

Healthcare Coverage - Fletcher Allen to extend benefits to workers on duty in National Guard

Healthcare Coverage - Florida Chamber of Commerce honors insurance company

Healthcare Coverage - Health insurance premiums outpace pay in West Virginia

Healthcare Coverage - Healthcare transaction service signs connectivity agreement with insurer

Healthcare Coverage - Legislative leaders say they can improve Kentucky health plan

Healthcare Coverage - Maryland state employee healthcare costs to increase

Healthcare Coverage - Medical software company signs 2-year contract with Brazilian insurance group

Healthcare Coverage - Mississippi city notifies 45 retired workers they must pay for health insurance

Healthcare Coverage - Open enrollment season is time to review healthcare coverage

Healthcare Coverage - Opportunities in the PPO sector to be discussed at conference

Healthcare Coverage - Payment for mental healthcare unclear in TennCare proposal

Healthcare Coverage - Pharma care company provides case management services for retirees

Healthcare Coverage - Private health plan introduced for children in central Texas

Healthcare Coverage - Software empowers patients to take charge of medical expenses

Healthcare Coverage - Some hospitals reject federal program for illegal immigrants

Healthcare Coverage - Sprint to offer workers domestic partner benefits

Healthcare Coverage - Survey finds women feel health plans critical to ensuring financial future

Healthcare Coverage - Teachers, school employees protest state health insurance plan

Healthcare Coverage - U.S. children's health insurance programs won't face cuts

Healthcare Coverage - What is a health savings account and what are its benefits?

Healthcare Disparities - White/black gap narrowing among elderly patients' access to medical tests

Healthcare Fraud - Developer fined $7,500, put on probation for healthcare fraud

Healthcare Incentives - Insurer pays doctors extra for preventative care

Heart Attack - Morning commuters' stress may heighten risk for heart attack, stroke

Heart Attack - Positive results of TP10 phase II study published

Heart Disease - Diabetic cardiomyopathy reviewed

Heart Disease - Taste genetics affects oral sensation, dietary behaviors, and disease risk

Heart Disease Risk - Exercise test predicts heart events in high-risk asymptomatic men

Heart Disease Risk Factor - Apolipoprotein A-I alterations raise triglyceride levels in mice

Heart Disease Risk Factor - Cardiovascular disease risk estimated in metabolic syndrome

Heart Disease Risk Factor - Dehydroepiandrosterone effect on heart disease risk is modest

Heart Disease Therapy - Sarpogrelate possesses cardiovascular and renal clinical potential

Heart Failure - First European orders placed for Ab5000 Circulatory Support System

Heart Failure Management - Reviews describes current recommendations for anticoagulation

Heart Surgery - Pharmacokinetics of argatroban during PCI determined

Heart Valve Replacement - ReValving System trial to begin in Siegburg, Germany

Hematology - Age and genetics are among factors that influence TGF-beta2 activity

Hematology - Contrast agent does not compromise therapeutic bone marrow-derived cells

Hematology - Cyclin D2 grants myeloid progenitors the ability to minimize cytopenia

Hematology - Heme triggers the nuclear export of Bach in order to regulate gene expression

Hematology - Myeloid growth factor increases marrow vascularity in children with neutropenia

Hematology - Reactions with haptoglobin-hemoglobin complex modulate NO reaction products

Hematology - Trends in anticoagulant therapy reviewed

Hemodialysis - Nosocomial transmission of hepatitis C virus plagues Tunisian dialysis patients

Hemoglobin - Marked differences noted in NO reactivity between human and rat hemoglobin

Hemophilia - Companies specializing in hemophilia partner to present symposium

Hemorrhagic Fever - Crimean-Congo hemorrhagic fever virus outbreak in Turkey confirmed by testing

Heparin Neutralization - Trial confirmed the safety and effectiveness of recombitant platelet factor 4

Hepatitis - Biotechnology company names clinical advisory board

Hepatitis - Diagnostics company enters hepatitis testing sector through new agreements

Hepatitis A Virus - Austrian butcher shop ordered shut after outbreak of hepatitis A

Hepatitis B - WHO stresses importance of childhood immunization against hepatitis B

Hepatitis B Vaccine - Hepatitis B vaccination effective in intravenous drug users

Hepatitis B Vaccine - Practical difficulties in managing hepatitis B in Asia-Pacific reported

Hepatology - CYP3A promotes endotoxemic liver injury through oxidative stress

Hepatology - Cellular disposition of arabinogalactan in hepatocytes determined

Hepatology - Main cytochrome P450 enzymes involved in safrole 1'-hydroxylation identified

Herbal Medicine - Committee on Herbal Medicinal Products holds inaugural meeting

Herpesvirus - (S)-MCT prodrug inhibits HSV-1 TK-transduced osteosarcoma cell growth

Herpesvirus Vaccine - Herpesvirus induces IFN-alpha via Toll-like receptor pathways

Hip Fracture Repair - The talon hip compression screw is effective in some unstable fractures

Hormone Replacement Therapy - ACOG issues state-of-the-art guide to HRT

Hormone Replacement Therapy - Menopause experts update position statement on estrogen and progestogen use

Hormone Replacement Therapy - Short-term impairment of gallbladder emptying associated with HRT

Human Coronavirus - Coronavirus 229E binds to CD13 in rafts and enters the cell through caveolae

Human Papillomavirus - Effects of HPV-18 proteins on keratinocyte gene expression determined

Human Papillomavirus Vaccine - DNA vaccine targeting HPV type 16 oncoprotein E6 developed

Human Papillomavirus Vaccine - Human papillomavirus in cervical cancers in Mozambique genotyped

Hypercholesterolemia - Fluvastatin well tolerated in renal-compromised, hypercholesterolemia patients

Hyperlipidemia - Sultosilate decreased concentration of small, dense, atherogenic LDL particles

Hypertension - Aggressive treatment of elevated BP is an essential part of transplant care

Hypertension - Angiotensinogen mRNA-stabilizing protein blockade lowers rodent blood pressure

Hypertension - Pharma company expands Diovan production at Swiss manufacturing site

Hypertension - Ultrasound method identifies conditions that may underly hypertensive myocardium

Hypertension - Unknown vegetable oil factors affect survival in spontaneous hypertension

Hypertension Therapy - Nifedipine prevents cardiac events as well as ACE inhibitor in diabetes

Hypertension Therapy - Valsartan with spironolactone prevents cardiac aldosterone escape in rats

Hypertension Vaccine - Vaccine elicits anti-angiotensin I antibodies in hypertensive subjects

Imaging - Research institute opens clinical imaging research lab in Canada

Imaging - Swedish regulatory authorities to approve novel imaging drug Hexvix

Imaging Technology - Confocal laser scanning microscope used in study of trophoblasts

Immune Activation - Monocyte activation differs between leprosy and TB in terms of IL-12 secretion

Immunization - Montana chicken pox vaccination rate well below national average

Immunology - C5a receptor essential for optimal generation of antiviral CD8+ T cell response

Immunology - Company initiates phase III clinical trial for FavId

Immunology - CpG DNA-mediated immune response may counteract pulmonary gene therapy

Immunology - E2 drives materno-fetal tolerance by expanding regulatory T cell compartment

Immunology - Gene transfer makes T-cell tolerance to transgene products possible

Immunology - Low T-cell receptor diversity associates with CTL escape in chronic hepatitis C

Immunology - Novel mAbs used to elucidate T-cell RANKL expression

Immunology - Oxidant stress links necroinflammation to fibrogenesis in autoimmune hepatitis

Immunology - Stress for newborns could weaken immune system later in life

Immunology - TaqMan RT-PCR assay sensitive/specific for respiratory syncytial virus detection

Immunology - Tonsillar tissue cultures preserve their structure for a limited time

Immunology - Trafficking of anti-complement receptor antibody investigated

Immunology - Two new HLA-DRB1 alleles have been discovered

Immunology - gp120/gp120 mAB/CCL5/CL12 do not alter DC activation and maturation processes

Immunotherapy - FDA accepts sBLA for expanded use of BEXXAR; decision expected by January 2005

Infection Control - Hand hygiene in NHS hospitals are out of date according to research

Infection Control - Infection control practices minimize nosocomial infection risk for GI endoscopy

Infection Control - Tissue bank to provide sterile soft tissue allografts using gamma irradiation

Infectious Disease -  Leishmania glycosomal protein import elucidated

Infectious Disease - Immunological effects of Rho GTPase degradation by CNF1 clarified

Infertility - Cancer scientists make unexpected discovery on sperm development

Influenza - Association launches flu-shot locator

Influenza - Blue Cross and Blue Shield of North Carolina offers free flu shots to members

Influenza - Highmark flu immunization campaign reduces care costs by an estimated $6.4M

Influenza - Importance of influenza vaccination as season opens stressed by U.S. officials

Influenza - Influenza A virus outbreak in Israel infected primarily neonates and infants

Influenza - NIH grant awarded for development of cell culture-based influenza vaccine

Influenza - New Mexico says it is time to get your flu shot

Influenza - Newest recommendations highlight the urgency for childhood influenza vaccination

Influenza - Vaccines are first line of defense for flu prevention, antivirals can play role

Influenza Vaccination - Nurses' association opposes mandatory flu vaccination policy

Influenza Vaccine - Virus-immunoglobulin complexes involved in early virus elimination

Influenza Virus - Active NF-kappa B signaling is prerequisite for influenza infection

Information Technology - American TeleCare recognized by Deloitte

Information Technology - Automation technology launched for genomics, proteomics labs

Information Technology - Bronx-Lebanon Hospital selects pharmacy IV automation technology

Information Technology - Cancer center quality diagnostics on every physician's computer via web tool

Information Technology - Century City Doctors Hospital to go digital with Siemens help

Information Technology - Companies form alliance to automate HIPAA transaction processing

Information Technology - Company announces voluntary recall of software application card

Information Technology - Consulting company launches regulations-focused program for life science clients

Information Technology - Consulting firm chosen to perform assessment of hospital information systems

Information Technology - Daou wins contract to build physician portal at Salem Hospital

Information Technology - Data management software that synchronizes databases installed for DermSergery

Information Technology - Enhancements announced for Performance Expert clinical decision support system

Information Technology - Government pushes to launch national electronic health information system

Information Technology - HIPAA deadline generates interest in technology company's security templates

Information Technology - Healthcare IT company announces $1.2 million contract with mail-order pharmacy

Information Technology - IT company forms physician advisory board to support growth in healthcare market

Information Technology - Information technology company automates University of Iowa Hospitals

Information Technology - Managed care company chooses payer software application

Information Technology - Order management system installed at medical center to improve patient safety

Information Technology - Pharmaceutical company signs $1.9 million software and services agreement

Information Technology - Premier Purchasing Partners awards contract to information technology company

Information Technology - Soarian IT system for healthcare providers installed at medical centers

Information Technology - Texas healthcare delivery company named one of most innovative users of IT

Information Technology - University of Utah center selects drug test system for sports lab

Information Technology - Voice communication software system for healthcare enterprises launched

Information Technology - Web-based software for analysis, reporting on raw DNA microarrays available

Information Technology - Wireless devices improve efficiency, but costs, other factors hinder acceptance

Injury Prevention - Big cities and small towns at similar risk of gun death

Insulin - Flamel announces termination of license agreement for long-acting insulin

Insulin Resistance - Role of renal natriuretic and depressor systems in hypertension studied

Insulin Sensitivity - Growth hormone enhances insulin sensitivity in young healthy adults

Irritable Bowel Syndrome - Biomedical food supplements product research featured in consumer publication

Irritable Bowel Syndrome - Depression co-morbidity associated with poor sleep, more severe IBS symptoms

Irritable Bowel Syndrome - Trial appears to validate finger-stick food-intolerance test

JC Virus - JC virus agnoprotein inhibits DNA repair after DNA damage

Kaposi Sarcoma-Associated Herpesvirus - KSHV ORF57 protein interacts with REF protein and acts as RNA export factor

Keratoacanthoma - Telomerase activity and COX-2 may be potential markers for certain cancers

Kidney Disease - Renagel REACH program expands access for Medicare beneficiaries

Kidney Disease - Studies strengthen kidney and heart disease link

Kleptomania - Researchers encouraged by early study results of drug to treat kleptomania

Knee & Ankle Kinematics - Physiological coxa varus-genu valgus may affect knee and ankle joint moments

Knee Replacement - Causes and treatment of postoperative stiffness reviewed

Lab Devices - FDA approves manufacture of Pyrotell Single Test Vials at new facility

Lab Tools - Flow cytometry system for clinical diagnostics released

Laparotomy - Data published from Entereg (alvimopan) phase III clinical trial

Learning - $36.5 million will fund centers to explore how humans, animals, machines learn

Legal Issues - Bennington hospital settles lawsuit involving missing patient records

Legal Issues - Court upholds ruling against insurer in tainted drinking water case

Legal Issues - Employee fired in 2002 sues Los Alamos lab

Legal Issues - Health Department says four employees inappropriately received money

Legal Issues - Judge dismisses jaw implant lawsuit against LSU

Legal Issues - Physicians fear district attorney's interpretation of fetal protection law

Legal Issues - Senator asks Stumbo to investigate health insurance contracts

Legal Issues - U.S. Government to collect $11.3M for expenses from silicone breast implants

Legal Issues - West Virginia attorney general sues Huntington nursing home

Legal Issues - Woman sues manufacturers of heartworm medicine

Legislative Issues - Survivors, physicians stress need for gynecologic cancer awareness bill

Leishmania - Chemokines play key role in Leishmania infections; scientists seek a model

Leishmaniasis - Research on trypanothione could lead to drug for three tropical diseases.

Leishmaniasis Therapy - Macrophage-specific drug delivery for leishmaniasis developed

Leishmaniasis Vaccine - Current status of leishmaniasis vaccine development reviewed

Leishmaniasis Vaccine - Progress in vaccine research for visceral leishmaniasis reviewed

Leptin Studies - Leptin regulates hypothalamic alpha-melanocyte-stimulating hormone

Leptin Studies - Role of leptin in farm animals reviewed

Leptin Studies - Thyrotropin-releasing hormone reduces leptin levels in children and adolescents

Leukemia - Arsenic could be suitable as first-line treatment in type of leukemia

Leukemia - Data demonstrates potential role for QUADRAMET in acute myeloid leukemia

Leukemia - Evidence builds for potential new cancer drug target

Leukemia Vaccine - Leukemia-derived dendritic cells become cells that stimulate T cells

Licensing Agreement - Genaissance Pharmaceuticals licenses vilazodone, an SSRI

Lipid Studies - Atorvastatin improves diabetic dyslipidemia

Lipid Studies - C/EBP gene replacement stimulates mitochondrial biogenesis in fat cells

Lipid Studies - Interleukin-15 directly regulates lipolysis in primary pig adipocytes

Lipid Studies - Intramuscular and liver triglycerides are increased in elderly adults

Lipid Studies - Study investigates heart fatty acid-binding protein

Lipid Studies - VLDL apolipoprotein increases with body weight and insulin resistance

Liver Disease - Scientists combine experimental therapies to fight gene disorders

Liver Transplantation - Cell line has potential application towards development of bioartificial liver

Liver Transplantation - HCV etiology of liver disease strongly associated with early acute rejection

Liver Transplantation - VEGF and its receptor mediate macrophage action in small-for-size liver grafts

Low-Carb Diet - Low carb dieters dismayed by rapid weight gains

Lung Cancer - Drug exposure may enhance in vitro invasiveness of lung cancer cell line

Lung Cancer - Genetic markers of heightened NSCLC metastasis risk identified

Lung Cancer - Novel candidate genes for systemic metastasis identified

Lung Cancer Vaccine - Peptides eliciting multiple responses in lung cancer identified

Lung Carcinoma - Peroxiredoxins seem to influence lung cancer progression

Lung Tumors - TTF-1 expression is specific for lung primary in typical and atypical carcinoids

Lyme Disease - Lyme disease levels off in northern New England

Lyme Disease - Tick bites in western Switzerland carry low risk of infection

Lymphoma - SGN-30 phase 2 clinical trial for cutaneous lymphoma initiated

Lymphoma Vaccine - EBNA1-specific CD4+ T cells are key for control of Burkitt lymphoma

Macular Degeneration - Pfizer, Eyetech and partner provide regulatory update on Macugen

Magnetic Resonance Imaging - Heart center, developer collaborate to research uses of MRI in cardiac care

Magnetic Resonance Imaging - Powerful MRI machine for decoding human brain unveiled at Illinois University

Magnetic Resonance Imaging - World's first open bore, 1.5 Tesla MRI system installed at Mayo Clinic

Malaria - Inflammatory cytokines increased in pregnant women with P. falciparum

Malaria - Role of Plasmodium falciparum genes in malaria in pregnancy reviewed

Malignant Melanoma - Ceplene trial in advanced malignant melanoma fails to meet primary endpoint

Management Systems - Florida healthcare system installs analytical management, productivity system

Market Analysis - Quality is key to success in selling antibodies

Medicaid - Lawsuit, lawmaker call for restoring Medicaid benefits in Mississippi

Medicaid - Mississippi attorney general intervening in lawsuit, trying to delay Medicaid cuts

Medicaid - Tennessee's Medicaid reforms could be national model

Medical Devices - Bioscience announces supply agreement with Resurrection Medical Center

Medical Devices - Franek to protect biomedical research instrumentation at medical school

Medical Devices - Hospital uses carotid stent device to open blocked arteries in the neck

Medical Devices - Medical device company launches instrument for soft-tissue cutting, coagulation

Medical Devices - Medical imaging software company shops U.S. FDA-cleared diagnostic software

Medical Devices - Nashville surgeons perform endoscopic bypass surgery without stopping the heart

Medical Devices - Noninvasive blood pressure monitoring device tested at children's hospital

Medical Devices - Vessel closure devices introduced at transcatheter cardiovascular meeting

Medical Education - "Hidden" curriculum of humiliation in medical school described

Medical Education - Is academic medicine not innovative enough?

Medical Technology - Life sciences company receives drug approval for ICG-PULSION in E.U. countries

Medical Technology - Study show optimizing patient fluid levels during surgery reduces hospital stays

Medical Training - Simulator training boosts confidence and skills for surgical residents

Medicare - Maryland General Hospital in compliance for Medicare

Medication Access - Accord on better access to essential medicines for poor reached at WHO meeting

Melanoma - Enrollment completed in phase III trial of Canvaxin

Melanoma - Pamidronate, zoledronate inhibit proliferation of human melanoma cells

Melanoma - U.S. FDA authorizes start of phase 2 clinical trial on melanoma vaccine

Melanoma Vaccine - Immune responses to peptide epitope in melanoma patients described

Memory - Brain-scanning life's memories yields new insights

Memory - Hippocampus damage determines effect on spatial and recognition memory

Meniere Disease - Inner ear gentamicin perfusion can provide long-term vertigo control

Meningitis - Parents encouraged to schedule missed vaccine doses of Prevnar for children

Meningococcal Disease - FDA panel recommends licensure of Menactra vaccine

Meniscus Repair - The Contour Meniscus Arrow is superior to the first-generation arrow

Menstruation - Menstrual cycle as a vital sign of health addressed at scientific forum

Mental Health - Analysis of children's risks spurs follow-up study on depressed adults

Mental Health - Biotech company closes series A financing, awarded grant for anxiety research

Mental Health - Polymorphisms in the serotonin 2C receptor are not linked to suicide risk

Mental Health - Storm stress mounts; experts see rising suicides and violence

Mental Health - The L/L genotype of catechol-O-methyltransferase correlates with panic disorder

Mental Health - Variations in the glucocorticoid receptor gene may alter emotional stability

Mergers & Acquisitions - Acquisition of Delaware biotech firm completed

Mergers & Acquisitions - Biotech companies announce definitive merger agreement

Mergers & Acquisitions - Edwards acquires percutaneous heart-valve technology company

Mergers & Acquisitions - Endocardial Solutions, Inc. acquired by cardio-focused medical devices company

Mergers & Acquisitions - Gambro expands into the emerging market for liver support

Mergers & Acquisitions - Global Medicine, Cryptic Afflictions merge

Mergers & Acquisitions - Silicone compounds manufacturer acquires Simethicone products

Mergers and Acquisitions - LivHOME, Inc., announces acquisition of AdvoLife, Inc.

Mergers and Acquisitions - Silipos, Inc., to be acquired for $15.5M

Mesothelioma - Diffuse malignant mesothelioma of the peritoneum and pleura studied

Metabolic Syndrome - Gender affects the incidence of metabolic syndrome in type 2 diabetic patients

Metabolic Syndrome - Nicotinic acid effective for managing lipids in patients with metabolic syndrome

Metabolic Syndrome - Nutritional aspects of cause and management of metabolic syndrome reviewed

Metabolic Syndrome - Statins are effective for management of metabolic syndrome

Metabolism Research - Nicholson Metabolic Pathways Charts to be developed, published in print, online

Metastases - Succinct interactions trigger interleukin-8 in invasive breast cancer

Metastasis - Molecular switch found that allows cancer cells to become mobile

Microarray - Device maker launches MAUI Mixer M4 for microarray hybridization

Microarrays - DNA microarrays have wide applications for genomewide expression analysis

Microbial Genetics - Clonal heterogeneity is seen in primary Mycobacterium tuberculosis cultures

Microbial Genomics - HLP gene expression in C. glabrata may play a role in hemolysin production

Microbial Resistance - Potent beta-lactam selection possible through integron-mediated resistance

Microencapsulation - Catalase encapsulated in polyelectrolyte microspheres characterized

Microencapsulation - Encapsulated oral enterotoxigenic E. coli vaccine developed

Microencapsulation - Microspheres induce adult-like CD8+ cytotoxic T cell responses

Microencapsulation - pH-triggered microparticles for peptide vaccination developed

Migraine Headache - Compound has been found to be efficacious in relief of acute attacks of migraine

Migraine Headache - Imitrex Tablets demonstrate rapid onset of pain relief in studies

Migration - Biologists show lizard migration is traced to Florida

Misconduct - Nurse arrested in slashing of nursing home feeding tubes

Molecular Biology - VEGF is a selective Down syndrome critical region I gene expression activator

Monoclonal Antibodies - Monoclonal antibodies and therapeutics reviewed

Mood Enhancement - New timed-released version of St. John's Wort available

Mucocutaneous Bleeding - New study confirms 80% of bleeding classifications from previous VWD study

Mucosal Immunization - Effect of particle size on transport across nasal mucosa studied

Mucosal Immunization - Improving M cell mediated transport across mucosal barriers reviewed

Mutagenesis - FSHD-linked mutants are responsible for severe phenotypes in Chinese patients

Mutagenesis - Homozygous myotonic dystrophy type 2 mutations produce more subtle phenotypes

Myasthenia Gravis - Asymptomatic type of disease also adversely affects pregnancy and birth

Mycobacteria - Genomic analysis distinguishes Mycobacterium africanum

Myelodysplastic Syndromes - EMEA accepts marketing authorization application for Vidaza for review

Myocardial Hypertrophy - Researchers caution care in modulation of myocardial growth

Myocardial Hypertrophy - Review delineates signaling pathways involved in aspects of cardiac hypertrophy

Myocardial Infarction - Edaravone before reperfusion was associated with smaller enzymatic infarcts

Myocardial Infarction - Garlic oil modulates lipid peroxidation and enhances enzyme systems

Myocardial Infarction - Guideline is a practical tool for providing care for patients with UA/NSTEMI

Myocardial Infarction - Left ventricular morphology and function studied in rabbit MI model

Myocardial Infarction - Little evidence supports systematic primary angioplasty over thrombolysis

Myocardial Infarction - No difference in results between enzyme inhibitors and receptor blockers

Myocardial Ischemia - Vasodilation may result from remodeling in response to plaque accumulation

Myocardial Perfusion - Marathon running does not cause marked change in cardiac function in healthy men

Nanotechnology - Autonomous nanomachine: a DNA fragment moves along a self-organized DNA track

Nanotechnology - Researchers develop silica-coated nanoparticles

Nanotechnology - Researchers find "on-off switch" for buckyball toxicity

Nanotechnology - Self-assembling nanotubes change colors, form "nanocarpet," even kill bacteria

Neck Pain Model - A novel rodent neck pain model is developed to evaluate persistent pain

Nerve Agents - Canadian government expands support for counter-terrorism antidote

Nerve Regeneration Model - Thyroxine and spermidine may enhance neural regeneration by a common mechanism

Neurodegeneration - Presenilin 1 gene mutations may be linked to early-onset Alzheimer disease

Neurology - Neuroradiology system enables real-time monitoring of entrance skin dose

Neurology - Pregnancy is a risk factor for restless legs syndrome

Neuroscience - Genetically engineered neural precursor cells treat murine spinal cord injury

Neuroscience - L-arginine induces differential NO production in rat hippocampus and striatum

Neuroscience - Magnocellular neuron gene expression determined in supraoptic nucleus

Neuroscience - Mechanisms of synaptic regulation by BDNF elucidated

Neuroscience - Pyrethroids modulate hippocampal acetylcholine release in rats

Neuroscience - Tissue plasminogen activator expression characterized in human CNS

Newborn Health - Study finds no deaths related to traditional infant bedding

Nocardia - PCR method developed for rapid identification of Nocardia farcinica

Non-Hodgkin Lymphoma - Marqibo to be reviewed by FDA Oncologic Drugs Advisory Committee

Non-Hodgkin Lymphoma - NHL patients do not receive full dose of chemo, study shows

Nosocomial Infection - Catheter removal recommended for patients with bloodstream infections

Nosocomial Infections - FDA grants Aurexis fast track designation

Nutrition - Benefits of omega-3s are good news for health-conscious consumers

Nutrition - Buyer beware: Product labels don't always measure up

Nutrition - Cinnamon water extract supplement for diabetics launched

Nutrition - Food company comments on study examining calcium and folic acid supplements

Nutrition - Group urges government to give consumers realistic nutrition advice

Nutrition - Powdered oils producer launches 3 OmegasT fatty acid

Nutrition - Study links low chromium levels to heart disease in men with diabetes

Nutrition - Testimony on dietary guidelines asserts negative messages are not effective

Obese Elderly - Michigan insurers offer grants for programs to reduce obesity

Obesity - Specific gene mutations bump up weight in obesity

Obesity Pathogenesis - Dosiinpartner has regulatory effect on high-fat diet-induced obesity

Obesity Pathogenesis - Inactivation of mutated melanocortin receptor linked to obesity

Obesity Pathogenesis - JIP1 scaffold protein essential for JNK activation in adipose tissue

Obesity Pathogenesis - Obesity and cardiovascular diseases reviewed

Obesity Pathogenesis - Role of arachidonate cascade during changes in adipocyte life cycle described

Obesity Surgery - Bone mineral content changes after surgical treatment of morbid obesity

Obesity Surgery - Inflammatory mediators normalize with weight loss in morbidly obese patients

Obesity Surgery - Preoperative upper endoscopy for laparoscopic gastric bypass is necessary

Obesity Therapy - Fasting-induced adipose factor increased by fenofibrate treatment

Obesity Therapy - Herbal formulation has anti-obesity effect on rats fed high-fat diet

Obesity and Diabetes - Adipocytes of obese subjects exhibit impaired activation of protein kinase C

Obesity and Diabetes - Chronic hyper-resistinemia results in abnormal glucose homeostasis

Obesity and Diabetes - Ginseng prevents onset of high-fat diet induced hyperglycemia and obesity

Obesity and Diabetes - Obesity, visceral fat, and poor glycemic control stimulate gluconeogenic flux

Obstetrics - Beta2 -agonist treatment enhances OTR mRNA expression in pregnant rats

Obstetrics - Case reported of postpartum sacral fracture presenting as lumbar radiculopathy

Obstetrics - Celecoxib no better than placebo for pruritis in cesarean-section patients

Obstetrics - Early data on remifentanil/propofol-based general anesthesia technique reported

Obstetrics - Effect of prenatal care on birth outcome assessed in Taiwan

Obstetrics - Laparoscopy can be useful for guiding D&C in angular pregnancy

Obstetrics - Left lateral and supine, wedged positions yield similar spinal block results

Obstetrics - Marijuana use could cause tubal pregnancies, murine study suggests

Obstetrics - Maternal nutrition affects fetal and neonatal reproductive development

Obstetrics - Maternal thyroid problems may cause very preterm delivery

Obstetrics - Monitoring technology for safer births studied at Kaiser Permanente

Obstetrics - Partnership aims to stop the invisible epidemic of maternal deaths

Obstetrics - Photo report follows six women during pregnancy and childbirth

Obstetrics - Study: Methimazole isn't safe during pregnancy

Obstetrics - Sublingual vs. vaginal misoprostol compared prior with first-trimester abortion

Obstetrics - Survey shows women unaware of infertility risk factors

Obstetrics - Term placentas from high-altitude pregnancies don't suffer hypoxic stress

Obstetrics - Two paracervical block techniques compared in first-trimester abortion

Obstetrics - pH-self measurement and immediate treatment helps prevent premature birth

Obstructive Sleep Apnea - At-home diagnostic test for sleep disorder developed

Obstructive Sleep Apnea - Dental appliances effective in treating sleep disorder

Occupational Health - Respirable coal dust modifies cytochrome expression in rat alveolar cells

Occupational Safety - Occupational safety institute published hazardous drug exposure report

Oncogenesis - Angiogenic restraint is lost as myeloma progresses

Oncology - Midkine promoter-driven gene therapy strikes down immortalized and tumor cells

Oncology - Pharmaceutical company announces developments in oncology program

Oncology - VEGF165 antagonizes semaphorin 3B-initiated apoptosis in cancer cells

Ophthalmologic Surgery - U.S. FDA approves device for separating corneal tissue during surgery

Ophthalmology - Researchers identify "light meter" that controls pupil constriction

Opportunistic Infection -  P. carinii CBK1 gene may function in signaling pathways for cell growth/mating

Oral Cancer - Saliva plays role in development of oral cancer

Orthopedic Surgery - Norian SRS injectable bone cement effective in tibial plateau fractures

Orthopedic Surgery - Utility of hip arthrodesis reviewed

Orthopedics - NSAID use, cigarette smoking not linked to aseptic loosening around THA

Orthopedics - Nazareth Hospital unveils new medical office building to serve community

Orthopedics - Orthopedics company names member to board, releases back bracing system

Orthopedics - Percutaneous gene transfer meets the challenge of treating nonhealing fractures

Orthopedics - Provider of human bone and bone connective tissue names senior vice president

Orthopedics - Tissue repair technology company receives patent for fiber-reinforced scaffolds

Osteomalacia - Bone densitometry useful in follow-up osteomalacia treatment

Osteomyelitis - FDA gives nod to additional phase II trial of INFECTON

Osteoporosis - BMD helps predict nonspine fracture risk in black women and white women

Osteoporosis - Exercise in the years preceding puberty increases bone mass for life

Osteoporosis - HA-coated screws decrease fixation failure incidence of trochanteric fractures

Osteoporosis - Lasofoxifene NDA submission earns pharmaceutical company $2M milestone payment

Osteoporosis - Orthopedists okay locking compression plates for osteoporotic forearm fractures

Osteoporosis - Osteogenesis around titanium implants affects bone turnover

Osteoporosis - Osteoporosis treatment submitted to European authorities for approval

Osteoporosis - Strontium ranelate is effective therapy with novel mechanism of action

Osteoporosis - Study compares weekly dosing efficacies of Fosamax and Actonel

Osteosarcoma - Enzyme maintaining chromosome ends is linked to cancer recurrence

Osteosarcoma Model - Mechanical strain can alter tissue-factor activity in rat osteosarcoma cells

Otitis Media - Inaugural Pulsys phase III trial to begin

Ovarian Cancer - Chemotherapy helps women with localized disease

Ovarian Cancer - Gene amplification is one mechanism for hK6 overexpression in ovarian cancer

Ovarian Cancer - Phase II trial data on carboplatin/paclitaxel/gemcitabine regimen reported

Ovarian Tumors - Case reported of late recurrence of juvenile granulosa cell tumor of the ovary

Pain - FDA approves ANDA for Oxycodone Hydrochloride Controlled Release Tablets, 80mg

Pain Control - Injectable microparticle-gel system provides prolonged local lidocaine release

Pain Management - Canadian pharmaceutical company realigns product pipeline

Pain Management - Neuropathic pain market growth predicted in report

Pain Management - Survey finds one in three Connecticut adults experience pain on a daily basis

Pain Management - Survey finds only 6% of adults recognize symptoms of nerve pain

Pain Management - ThermaCare launches heat wrap for knee pain

Pain Management - Understand your prescription painkillers, advises foundation report

Pain Medicine - Bupivacaine-loaded microcapsules provide durable analgesia

Pain Medicine - Chronic opiate use may raise vulnerability to stress

Pain Medicine - Imagery reduces children's postoperative pain

Pain Medicine - Phase III trial begins for analgesic Bicifadine

Pain Medicine - Temporal characteristics of descending inhibitory control vary by gender

Pancreatic Cancer - Neurobiological gene therapy company signs license agreement for enzymes

Panic Disorder - Mismanagement of panic disorder argues for mental health professionals in EDs

Parkinson Disease - Depression also a problem in patients with Parkinson disease

Parkinson Disease - Discovery of gene-expression changes leads to advancement in Parkinson research

Parkinson Disease - Hand-movements can be predicted in patients with Parkinson disease

Parkinson Disease - Nasal powder program expanded with new production capability

Parkinson Disease - Study finds limited role for DJ1 in PD susceptibility

Patents - Biopharmaceutical company announces European patent developments

Patents - Companies win patents supporting Alzheimer disease immunotherapy treatments

Patents - Company awarded patent on human P2Y4 receptor

Patents - Company receives European patents on its encapsulation technology

Patents - Company receives U. S. patent for de-identified patient encryption process

Patents - Company receives notice of allowance for MEDI-SAVER patent

Patents - Composition-of-matter patent issued covering A.G.E. Crosslink Breakers

Patents - Court overturns cord blood patent infringement verdict, denies injunction

Patents - Early trial set in patent infringement lawsuit against Schering-Plough

Patents - Gen-Probe settles patent dispute

Patents - Genomics company receives international patents

Patents - Patent granted for InFORM Radiology Workflow Solution

Patents - Patent issued for wireless capability on infusion system

Patents - Rights obtained to polymer drug delivery patents

Pathogen Coding - PathoGene is a web-based pathogen coding and analysis resource

Pathogen Detection - Companies to co-develop automated system to identify airborne pathogens

Patient Monitoring - Company offers turnkey cardiac ion channel assays, in vivo CVD assessments

Patient Protection - New Jersey Committee approves measure to protect patients

Patient Safety - ShrinkSafe paralytic identification bands launched for high-alert medications

Pediatric Cancer - Researchers report on professional collaboration with cancer patients, families

Pediatric Leukemia - FDA Oncologic Drugs Advisory Committee to review clofarabine

Pediatric Obesity - New DVDs to help combat childhood obesity

Percutaneous Coronary Intervention - Angiox approved in Europe

Percutaneous Coronary Intervention - Company gets E.C. approval to market anticoagulant for PCI patients in Europe

Percutaneous Coronary Intervention - Strategies are proposed to increase use of percutaneous coronary intervention

Peri-implantitis - Er:YAG laser can disrupt osteoblast mitochondria activity

Personnel - AMN Healthcare Services appoints chief financial officer

Personnel - Adamson to remain as CEO of Medical Staffing Network Holdings

Personnel - Andrea Natale joins device company's medical advisory board

Personnel - Andrew K.W. Powell named VP and general counsel to dental/derma-focused company

Personnel - Anesthesia company appoints Ann Showan to oversee mid-Atlantic clinical affairs

Personnel - Arthur B. Modell to head board of governors for new heart institute

Personnel - Biopharm company names new VPs of business development, intellectual property

Personnel - Biopharmaceutical company CFO retires, successor named

Personnel - Biopharmaceutical company announces appointment of chief scientific officer

Personnel - Biopharmaceutical company announces formation of scientific advisory board

Personnel - Biopharmaceutical company announces medical director

Personnel - Biotech company appoints board members

Personnel - Catherine Kniker named VP of corporate strategic development at device firm

Personnel - Clinical research organization names Dr. Elizabeth Bonomo VP

Personnel - Clinical research organizations appoints director of global product development

Personnel - Company specializing in stem cells announces new CEO

Personnel - Contract research organization announces vice president, human resources

Personnel - Coventry CEO Allen F. Wise retires; CFO Dale B. Wolf named as successor

Personnel - Crdentia appoints Vicki Smith as interim CFO

Personnel - Dawn Lepore appointed CEO and chairman of the board of drugstore.com

Personnel - Dean Haubrich, PhD, named head of project management for TB organization

Personnel - Deborah Jorn, Stephen Farrand named to new posts at science-based drug company

Personnel - Device company appoints Martin Joyce as chief financial officer

Personnel - Diagnostic imaging services announces resignation of chief executive officer

Personnel - Diversity in U.S. healthcare professions is separate, unequal, commission says

Personnel - Dr. Kimberley Forbes-McKean named SVP, chief technical science officer

Personnel - Drug discovery company names vice president finance

Personnel - Drug-sampling solutions provider names executive director, business development

Personnel - Dunton and Wenzinger appointed to biopharmaceutical company's board of directors

Personnel - Edmund Mickunas named VP regulatory and clinical affairs

Personnel - Gene technology company appoints new member to board of directors

Personnel - Genomics company names new chairman, president

Personnel - George Mark Children's House appoints new executive director

Personnel - Glen A. Fine named new executive VP of standards institute

Personnel - HealthSouth appoints Mark Tarr president of inpatient division

Personnel - Healthcare company appoints chief scientific officer

Personnel - Healthcare system responds to Illinois governor's facility board appointments

Personnel - Ion channel drug discovery company appoints vice president, discovery

Personnel - Joe W. Smith named to board of directors at surgical device company

Personnel - Life sciences-focused legal firm hires two expert biotech patent attorneys

Personnel - McGovern Institute at MIT announces new director

Personnel - Medical and wipes company names product manager

Personnel - Medical device manufacturer names chief science officer

Personnel - Merial announces retirement of executive chairman

Personnel - NDCHealth announces organizational change

Personnel - New Jersey Biotechnology Council elects new officers, expands leadership team

Personnel - New president appointed at biotech firm

Personnel - Newborn health company makes personnel announcements

Personnel - Nonprofit pharmaceutical company announces new board member, senior staff

Personnel - Oncology company appoints Michael Kishbauch to its board of directors

Personnel - Outsourced sales and marketing company names executive VP human resources

Personnel - Pharmaceutical company announces new board member

Personnel - Pharmaceutical company announces new personnel appointments

Personnel - Pharmaceutical company appoints Paul Hamelin as president, COO

Personnel - Pharmaceutical company names Les Paul as VP, medical affairs

Personnel - Pharmaceutical company names vice president, product development

Personnel - Pharmaceutical company promotes Terry Prime to VP of marketing

Personnel - Richard K. Whitney joins laboratories board, former director resigns

Personnel - Scott Borland named vice president of engineering by drug delivery company

Personnel - Scott Dustin named VP of sales and marketing, Global Med Technologies

Personnel - Specialty pharmaceutical company announces management appointments

Personnel - Susan Harris named president of labor relations firm's healthcare division

Personnel - Takashi Nakamura joins GeneEd's business advisory board

Personnel - Thomas P. Russo joins DNA-focused company as executive VP and CFO

Personnel - Walter Singleton named vice president, clinical and regulatory affairs

Personnel - Worker's compensation and liability assistance company names president

Pertussis - Nine Cascade County residents diagnosed with whooping cough

Pharmacy Management - Ellipticare to manage Clarian Health Partners' outpatient pharmacies

Pharmacy Services - Automation persuades pharmacy to implement new IT

Philanthropy - Dell supplying computers for U.S. CDC emergency response center

Philanthropy - Vermont couple donate $2.5 million to Fletcher Allen

Physical Activity - Exercise increases anti-oxidation in liver of obese Zucker rats

Physical Activity - Role of physical education in promoting youth physical activity reviewed

Physiology - Effects of training and detraining on muscle satellite cells determined

Physiology - Neuropeptide Y antagonism lowers reflex cutaneous vasoconstriction

Polio Vaccine - Simian virus-tainted polio vaccine does not raise childhood cancer risk

Polycystic Ovary Syndrome - Metformin being evaluated for improving PCOS symptoms

Polymerase Chain Reaction - Device company launches OpenArray Transcription Analysis system

Preeclampsia - Cellular endothelial compartment increase may play pathologic role

Preeclampsia - Preventive effect from aspirin depends on early treatment of sufficient dose

Prenatal Genetic Diagnosis - Microarray analysis of fetal DNA in amniotic fluid identifies sex, aneuploidy

Prescription Drug Cost - Up to 53% of users of foreign prescription drug sites are U.S. seniors

Prescription Drugs - Allergan psoriasis treatment tazarotene denied approval by FDA

Prescription Drugs - Drug maker warned sales reps to keep quiet about suicide risk

Prescription Drugs - Health group proposes bills to cut drug costs in Maryland

Prescription Drugs - Program to help poor in New Mexico get medications

Procurement - Broadlane announces procurement services for healthcare providers

Product Distribution - Medical devices company picks distributor for rapid skin anesthesia product

Product Licensing - Corgentech licenses peptide-delivery system to use with TF Decoys

Product Licensing - Flamel licenses Micropump technology for lansoprazole

Product Licensing - GTC Biotherapeutics grants license for Protexia

Product Licensing - GTG grants genetic-testing license agreement

Product Licensing - Licensing agreement reached for oral formulation of human growth hormone

Product Licensing - U.S. FDA grants tentative approval for generic antihistamine HCL tablets

Professional Education - Nursing schools turning students away

Professional Standards - The terms "plastic surgery" and "cosmetic surgery" are perceived differently

Prognostics - Prognostic markers determined for renal failure severity in PUUV infection

Prostate Cancer - A glass of red wine a day may keep prostate cancer away

Prostate Cancer - Combination trial to study MDX-010 with GVAX prostate cancer vaccine

Prostate Cancer - Cottonseed drug is cancer treatment booster - patient trials now planned

Prostate Cancer - Elderly African American men less likely to undergo prostate cancer screening

Prostate Cancer - Gene expression in androgen independent disease characterized

Prostate Cancer - Lycopene slows human prostate tumor growth in mice

Prostate Cancer - Patient enrollment commences in U.S. prostate cancer study of Modrenal

Prostate Cancer - Report on prostate cancer frames debates on treatment

Prostate Cancer - Serum PSA screens have high sensitivity in Finnish population

Prostate Cancer - Trial to assess if Zyflamend prevents prostate cancer

Prostate Cancer Vaccine - Antigen-derived peptides induce CTLs in prostate cancer patients

Prostate Cancer Vaccine - DNA vaccine elicits immune response in patients with prostate cancer

Prostate Cancer Vaccine - Gene-based therapy in prostate cancer reviewed

Prosthetic Dentistry - Parallel guiding planes increase stability of removable partial dentures

Protein Regulation - Variations in poly(A)-binding protein-interacting protein 2 sway angiogenesis

Protein Signaling - Structural differences identified in transmembrane of mouse, human NKG2D

Proteomics - Apo E has isoprotein-specific effects on many biological processes and diseases

Proteomics - Foxo1 is an essential element of vascular development

Proteomics - Function of S. cerevisiae Yaf9p protein clarified

Proteomics - HMGA1-mediated gene regulation is tissue-specific

Proteomics - Microenvironment has a strong bearing on the activity of syndecan-1

Proteomics - Neuroglycan C is a member of the neuregulin family

Proteomics - Novel assay facilitates analysis of NK cell microsomal proteins

Proteomics - Photo-CIDNP NMR methods for protein fold imaging reviewed

Proteomics - Platelet factor 4 uses several avenues for angiogenesis suppression

Pseudomonas Aeruginosa - Surface plasmon resonance can detect P. aeruginosa on gold

Psoriasis - Enrollment completed for phase II trial for Psoraxine

Psoriasis - Marketing authorization for psoriasis drug granted by European Commission

Psychology - Preadolescents' body image concerns need attention

Public Health - Customizable information delivery system for HIV/AIDS community launched

Public Health - Mexican American communities offer health benefits to long-time residents

Public Health - Professor: Local health campaigns not reaching adults with bad habits

Public Health - Rural veterans face lower quality of life than urban counterparts

Public Health - Socioeconomic status is a significant predictor in understanding an outbreak

Pulmonary Hypertension - Endothelin ETA receptor antagonist reverses pulmonary hypertension

Pulmonary Medicine - Forced inspiratory flow reference values determined for school-aged children

Pulmonary Research - Ascribing function to specific ion channels in the human lung is soon possible

Pulmonary Tuberculosis - Late diagnosis of pulmonary tuberculosis led to community outbreak

Pulse Oximetry - Flexistat Oximetry Sensors receive U.S. FDA approval

Quality Assurance - Cigna HealthCare makes gains in healthcare quality

Quality Assurance - Draft standards for health plans address issues in consumer directed healthcare

Quality Assurance - Health plan named to top 10 by National Committee for Quality Assurance

Quality Assurance - Hospital considers changing practices for patient follow up

Quality Assurance - New York finds incomplete data in incidence reports

Quality Assurance - Pennsylvania hospital mortalities down, readmissions up

Rabies - More than 100 in Minnesota town require rabies shots

Radiation Therapy - Companies partner to distribute OneDose patient dosimetry system

Rankings - Express Scripts named to the Information Week 500

Rankings - LIMS provider named to Deloitte Technology Fast 50 Program for Delaware Valley

Receptor Studies - Green-fluorescent-protein-based assay characterizes G-protein-coupled receptors

Receptors - Review focuses on interaction between beta-AR and OPR in the heart

Receptors - Understanding receptors will provide a better approach to treating heart failure

Rectal Cancer - Immunohistochemical markers of poor prognosis identified

Regulatory Issues - Amendment to PMA-S submitted to FDA in response to not-approvable letter

Regulatory Process - Company reiterates Enhanze SC NDA timeline

Renal - ADPKD disease pathways elucidated

Renal Cancer - SU5416 treats metastatic kidney cancer in a von Hippel-Lindau syndrome patient

Reproductive Biology - Altered LH receptor splicing not involved in luteolysis

Reproductive Biology - Circadian Clock mutation disrupts estrous cyclicity, maintenance of pregnancy

Reproductive Biology - Coagulation factor function differs between pregnancy and platelet formation

Reproductive Medicine - Sperm-specific enolase characterized

Reproductive Physiology - Late gestation estradiol secretion required for respiratory response to hypoxia

Research Funding - Agriculture secretary announces grants to promote healthier children

Respiratory Distress - Cytokine release after esophagus resection suggests subclinical lung injury

Respiratory Medicine - Nonanatomical Dexter model suitable for endoscopic dexterity training

Respiratory Syncytial Virus - Recombinant respiratory syncytial viruses characterized

Respiratory Syncytial Virus - V beta 14+ T cells mediate disease induced by RSV G glycoprotein

Retinal Regeneration - First derivation of retinal cells from embryonic stem cells; may treat blindness

Retinitis Pigmentosa - Degeneration status conveys transduction efficiency in mice with retinopathy

Retinoblastoma - Long-term efficacy of electron beam radiotherapy determined

Retinopathy of Prematurity - Limited hyperoxia therapy could help some newborns without harming their eyes

Retrovirus - NC structural interactions with other Gag domains necessary for Psi RNA binding

Retrovirus - Retroviruses spread by induction of virological synapses

Rheumatology - Cyclooxygenase inhibitors block enzymes that promote rheumatoid arthritis

Rosacea - Rosula NS medicated pads launched

SARS Coronavirus - Pivotal role of SARS coronavirus E protein in viral budding elucidated

SARS Epidemiology - SARS rates vary among three categories of hospital workers in Hong Kong

Schistosomiasis - Parasite detection abilities compared between MAb dipstick test and microscopy

Sedation - Phase III clinical trials of AQUAVAN Injection begin

Sexual Desire Disorder - FDA grants priority review to testosterone transdermal system for HSDD

Sexual Dysfunction - Positive results reported on phase II study of LibiGel

Sexual Health - Moffitt Cancer Center in Florida adds sexual medicine service

Shingles - New guideline evaluates treatments for post-herpetic neuralgia

Shoulder Injuries - Overhead athletes may have muscle imbalances in the dominant arm

Shoulder Replacement - Utility in four-fragment proximal humerus fractures determined

Sinusitis - Severe complications from acute sinusitis will affect young males in late winter

Skin Cancer - American Academy of Dermatology awards 2004 Shade Structure Grants

Skin Diseases - Cytochrome P450 play a role in drug metabolism

Sleep Apnea - Obstructive sleep apnea did not elicit overnight changes in natriuretic peptides

Sleep Disorders - Palatal implants provide effective snoring relief

Smallpox - FDA clinical hold for ACAM2000 removed, BLA submission planned

Smoking Cessation - New drug-free smoking cessation product introduced

Smoking Cessation - Statewide smoking cessation line helps Ohioans quit

Social Psychology - Wealth does not create happiness and it doesn't build a strong country, either

Spinal Cord Injury - Controlled release of NT-3 from fibrin gels used for spinal cord injury

Spinal Cord Injury - Protective effects of anti-CD11d antibody clarified

Spinal Cord Injury - Structure of Nogo-A protein characterized

Sports-Related Injuries - Motion DNA launches high school sports testing programs

Staffing - New VISTA staffing unit offers temporary oncologist staffing

Staphylococcus Aureus - Drug-resistant bacteria increasingly causing infections in healthy people

Stem Cell Research - CCR7 expression on BM-derived dendritic cells is indication of cell maturity

Stem Cell Research - Endothelial progenitor cells may hold the key to tissue regeneration

Stem Cell Research - Indian hedgehog genes hone the hematopoietic support ability of stromal cells

Stem Cell Research - Model transforms stem cells to express breast cancer estrogen receptor

Stem Cell Research - NIH grants new money for more research into Alzheimer, spinal cord injuries

Stem Cell Research - Nestin expression lost in neural stem cells through proteasome/Notch signaling

Stem Cell Research - Neural progenitor cell lines inhibit tumor growth

Stem Cell Research - Neural stem cells improve sensorimotor deficits in brains with focal ischemia

Stem Cell Research - Newly generated neurons evidenced in the olfactory bulb

Stem Cell Research - Notch signaling important for primitive to definitive neural SC differentiation

Stem Cell Research - PGE2 produced by COX-2 increases BMP-2 expression via binding the EP4 receptor

Stem Cell Research - STAT6 deficiency increases bone marrow-committed myeloid progenitors

Stem Cell Research - Skin-derived stem cells differentiate into neural lineages

Stem Cell Research - Slow-dividing fraction of SCs may be associated with primitive function

Stem Cell Research - Stem cells have potential to regenerate damaged inner ear

Stent Coatings - Tetrahedral amorphous carbon may be effective for vascular stent coatings

Stock Market - Changes to stock market index fund announced

Streptococcus Vaccine - Group A Streptococcus strains causing epidemics analyzed

Stress - Americans had strong need for spiritual support following 9/11 attacks

Stress - Vietnam veterans had higher death rates after discharge than other veterans

Stroke - New Jersey hospital to offer newly approved stent device to prevent stroke

Stroke - Synthetic drug used to break up clots based on bat saliva

Stroke - Umbilical cord blood-derived stem cells given intravenously reduce stroke damage

Student-Athletes Health - Preparticipation Physical Evaluation updated for student-athletes screening

Substance Abuse - New study shows hope for treating inhalant abuse

Sudden Hearing Loss - MRI identifies causes of sudden deafness

Surgical Techniques - Company demonstrates end-to-side surgery tool for reconnecting tissue

Surgical Techniques - Patient dies after surgery telecast live to medical meeting

Systemic Lupus Erythematosus - Detoxification deficiency linked to increased oxidative stress in SLE etiology

Telecommunications - Cingular Wireless assists HealthNet Community Health Centers

Testicular Dysgenesis Syndrome - Hypospadias, cryptorchidism, and testicular cancer have common risk factors

Therapeutic Cloning - Creator of Dolly the sheep applies for license to clone human cells for research

Thrombocytopenia - Low-molecular-weight and unfractionated heparins contraindicated in HIT patients

Thrombolysis - Cardiac functional status after rapid thrombolysis for acute MI studied

Thrombosis - Lepirudin prevents lethal effects of Shiga toxin in dogs

Timothy Syndrome - Researchers determine genetic cause of cardiac disorder

Tissue Engineering - Engineered chondrocytes reconstruct fibrocartilage zone at bone-tendon junction

Tissue Engineering - U.S. Army evaluating recombinant human fibrinogen product

Tobacco Use - Nicotine metabolism characterized in subjects with CYP2A6 deletion

Tobacco Use - The lung may act as a short-term depot for nicotine

Total Hip Arthroplasty - Cement microcracks occur more often in femoral component thin-mantle regions

Toxicology - Perchlorate exposure not harmful to newborns, pregnant women, other adults

Transfusion Medicine - Blood alternative reduces risk of disease

Transfusion Medicine - Many blood donors in southern Taiwan harbor the D/H strains of SEN virus

Transgenics - Mutant mice reveal the characteristics of pseudogenes

Transplant Medicine - CMV match is a key factor for survival following heart and lung transplantation

Transplant Medicine - Genetic signatures profile kidney transplant rejection status

Transplant Medicine - Interferon-gamma infusion prepares recipients for genetically modified cells

Transplant Medicine - Metabolite assays detect 6-mercaptopurine toxicity after liver transplantation

Transplant Medicine - New protocols in kidney-pancreas transplantation produces better results

Transplant Medicine - Reducing exposure to calcineuron inhibitors may reduce renal insufficiency

Transplant Medicine - Renal transplantation results from DCD and DBD donors are equivalent

Trichomoniasis - Xenostrip-Tv is rapid and accurate test for Trichomonas vaginalis

Tuberculosis - CDC funding to be used for development of TB vaccine trial sites in India

Tuberculosis - Doctor wants more funding for tuberculosis

Tuberculosis - Medical Services invited to participate in tuberculosis study

Tuberculosis Diagnosis - ESAT-6 and CFP-10 protein peptides used to detect M. tuberculosis

Tuberculosis Transmission -  Mycobacterium tuberculosis transmitted via lung transplantation

Tuberculosis Vaccine - DNA vaccine activates CD8+ cells and reduces lung injury in TB

Tumor Suppression - The combretastatin OXI4503 boosts tumor vessel collapse via apoptosis

Tumor Therapy - Antisense drug targeting STAT-3 demonstrates significant antitumor activity

Type 2 Diabetes - British civil servants with lower employment grade have more diabetes risk

Type 2 Diabetes - Millions of Asian Americans and Pacific Islanders at increased risk

Urinary Tract Infection - A glass of cranberry juice a day may keep bladder infection away

Urinary Tract Infection - Gatifloxacin regimens as effective as oral ciprofloxacin for UTI

Urinary Tract Infection - Proquin XR New Drug Application accepted for review by U.S. FDA

Urology - Bladder-to-urethral reflexes in urinary continence mechanisms studied in rats

Utilization - Sociologists to map disease, death by analyzing prescription drugs

Vaccine Adjuvant - Coding sequence optimization enhances enterotoxin expression in tobacco

Vaccine Development - Antigen injection into anterior chamber activates splenic CD8+ cells

Vaccine Efficacy - Effect of freezing rate and excipient on vaccine infectivity compared

Vaccine Efficacy - Pseudovirus encoding IL-2 restores immune responses to vaccines

Vaccine Vector - Modified vaccinia virus induces moderate activation of dendritic cells

Vasculitis - Antiviral therapy helps manage polyarteritis nodosa in hepatitis B patients

Vasoconstriction - Findings should lead to the design of new, potent, and selective analogues

Vector Development - Lambda phages display enhanced transduction capabilities upon modification

Vector Development - Novel human artificial chromosomes facilitate gene delivery

Ventricular Myocytes - A long intracellular loop may be involved in inhibition of NCX1 by amiodarone

Vessel Stenosis - A new stent can grow as the child grows

Viral Proteomics - Hepatitis C virus F protein and core protein are dissimilar

Virology - A new assay uses a single platform to analyze hepatitis C virus RNA

Virology - Coliphage PR772 evaluated for use in virus filter performance testing

Virology - Genetically modified adenoviruses show promise for treating gliomas

Virology - Transfected liver cancer cells offer a new venue for exploring hepatitis B

Virology Vaccine - Progress on vaccine strategies against viral infections reported

Vitiligo - Combined calcipotriene and corticosteroid can repigment vitiligo

Vulvar Cancer - Diagnosis and treatment of relatively rare gynecologic cancer discussed

Water-Borne Illness - New arsenic drinking water standard may still be toxic

Water-borne Disease - Non-biological sequential disinfection system developed

Waveforms - Analysis of untransformed radial waveforms produces smaller errors

Weight Loss - Researchers link citrus to weight loss, reduced heart disease and cancer

West Nile Virus - New West Nile virus infection in Mobile County, Alabama

West Nile Virus - Recovery at 1 year is poor in elderly persons with West Nile virus infection

West Nile Virus - Second Illinoisan dies of West Nile virus

West Nile Virus - Two new cases of West Nile reported

West Nile Virus - West Nile virus spread rapidly throughout the U.S.

Wilms Tumor - Shorter course of chemotherapy beneficial for children with Wilms tumor

Wound Healing - Transforming growth factor-beta 3 may not promote wound healing

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