Cardiology
Acetyl-CoA carboxylation determines malonyl-CoA concentration in the heart
Published in Health and Medicine Week, October 18th, 2004
According to a study from the United States, "The goal of [our] study was to test the relationship between malonyl-CoA concentration and its turnover measured in isolated rat hearts perfused with NaH13CO3 ."
A.E. Reszko and colleagues of Case Western Reserve University explained, "This turnover is a direct measurement of the flux of acetyl-CoA carboxylation in the intact heart. It also reflects the rate of malonyl-CoA decarboxylation, i.e., the only known fate of malonyl-CoA in the heart."
"Conditions were...
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