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Health and Medicine Week

Susan Hasty, Publisher

Table of Contents . . . December 6th, 2004

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Health and Medicine Week | Other Publications

Addiction Medicine - Prenatal alcohol exposure has effects far beyond fetal alcohol syndrome

Aspirin Resistance - Collaboration for aspirin-resistance testing announced

Hypertension Epidemiology - Adult hypertension in United States on the increase

Urinary Tract Infection - Genetic "switch" may enable bacteria to survive stressful conditions

Weight Loss - Low-fat diets better long-term

AIDS/HIV Pathogenesis - CD4+ T cell depletion in HIV occurs predominantly in gastrointestinal tract

AIDS/HIV Pathogenesis - HIV linked to depletion of CD4+ T cells from effector sites in GI tract

AIDS/HIV Vaccine - Novel and promiscuous CTL epitopes in conserved regions of Gag identified

AIDS/HIV Vaccine - Therapeutic HIV vaccines reviewed

AIDS/HIV Vaccine - Vaccine provides T-cell-mediated protection in monkeys after SIV challenge

Abortion - Corrections being made to Louisiana abortion brochure

Actinomycetoma Vaccine - IgM protects mice from actinomycetoma infection by Nocardia brasiliensis

Acute Lung Injury - High von Willebrand factor levels linked to poor outcome

Acute Lymphoblastic Leukemia - Oral etoposide has a cytoreductive effect in relapsed ALL

Acute Myeloid Leukemia - L-ascorbic acid represses NF-kappa B/COX-2 expression in acute myeloid leukemia

Addiction Medicine - Cocaine pharmacology and pharmacotherapies for its abuse reviewed

Addiction Medicine - Company licenses oral drug to treat impulse control disorder

Addiction Medicine - Imaging study finds a structural difference in the brains of cocaine addicts

Adenovirus - Nuclear localization of adenovirus E4orf4 protein correlates with cell death

Adrenoceptors - New scheme for identifying alpha1A -adrenoceptor splice variants is proposed

Adverse Drug Effects - Cyclosporine A exposure in utero linked to adulthood kidney problems, high BP

Adverse Drug Effects - Dinitrophenol-related fatality reported

Adverse Drug Effects - Long-term use of depo-provera contraceptive injection may cause osteoporosis

Adverse Drug Effects - Minor behavioral deficits seen in rats exposed prenatally to synthetic estrogen

Adverse Drug Effects - Retinoic acid exposure in utero alters cranial neural crest gene expression

Adverse Drug Events - New worries tarnishing arthritis drugs

Adverse Side Effects - Rare cutaneous reactions arise following hepatitis B vaccine immunization

Aesthetic Medicine - New platform design launched for company's aesthetic systems

African Sleeping Sickness - Study patients clear African sleeping sickness parasite in DB289 phase IIb trial

Aging - Scientists successful in "death clock" gene hunt

Agriculture Research - Company contributes funds to SIUE National Corn-To-Ethanol Research Center

Alcohol Abuse - Changes in cannabinoid brain receptor play role in alcoholism relapse

Alcoholic Liver Disease - Intracellular SAH removal may be therapeutic option in alcoholic liver disease

Alcoholism - Brain-derived neurotrophic factor appears to modify elements of alcoholism

Allergy Medicine - Clinical trial study for PreHistin to begin

Allergy Medicine - Parenteral immunization to beta-lactoglobulin modifies intestinal structure

Alzheimer Disease - CE Mark issued for AlzheimAlert Test Kit making it available in European Union

Alzheimer Disease - Compound in apples may help fight neurodegenerative disorders

Alzheimer Disease - Cytokines/GSTO genetic polymorphisms do not play major role in Alzheimer disease

Alzheimer Disease - Immune responses to A-beta vaccine are different in C57BL/6 and B6D2F1 mice

Alzheimer Disease - Inhibitors of A-beta oligomerization identified

Alzheimer Disease - Melatonin inhibits amyloid beta-induced apoptosis

Alzheimer Disease - Pharma companies collaborate on Alzheimer and Parkinson disease candidates

Alzheimer Disease - Taking statin slowed progression of Alzheimer disease, new study shows

Amino Acid Supplementation - Branched-chain amino acid supplementation does not alter performance in the heat

Amyotrophic Lateral Sclerosis - ALS drug candidate Myogane gets U.S. FDA Fast Track designation

Anemia - Study: FG-2216 increases endogenous EPO production in humans

Anesthesia - Consider the effect of anesthesia when measuring circulating blood elements

Anesthesia - Consider the presence of anesthetics when studying control of heart rate

Anesthesia - Target-controlled propofol infusions characterized

Angina - Earlier cardiac catheterization reduces risk of mortality in high-risk patients

Angina - Vasopressin and platelet-activating factor interact to provoke ischemia

Angiology - ERK played a role in mediating H2S-induced apoptosis of smooth muscle cells

Angiology - Genomic response to adrenoceptor activation determined in aortic smooth muscle

Angiology - High glucose levels impair nitric oxide-related VEGF synthesis

Angiology - Hypoxia and erythropoietin cause endothelial cells to generate nitric oxide

Angiology - Kininogen-deficient developed increased cholesterol without plaque formation

Angiology - Outflow location on ventricular assist devices may affect patient response

Angiology - Study demonstrated concurrent entrainment of all carotid baroreflex measurements

Angiology - Vascular endothelial growth factor mediates the response of c-Myc to hypoxia

Angiophototherapy - Preclinical data of Antrin to treat vulnerable plaque presented at AHA

Anthrax - Company completes first phase of ThraxVax design

Anthrax Vaccine - Mass value for IgG in standard anthrax reference serum assigned

Anti-Inflammatories - Anti-inflammatory compounds in middle age may decrease CV events in aging

Antibiotic Resistance - Molecular technique shows promise in destroying drug resistance in bacteria

Antibody Selection - New technology promises to cut time in discovery of antibody drugs

Antimicrobials - C-terminal heptapeptide has key role in maintaining GGN4 pore-forming activity

Antisense Technology - GAD 67KD antisense leaves colon cancer cells susceptible to cancer therapy

Antitumor Activity - Intratumoral CCL5 overexpression delays tumor growth

Aortic Valves - Novel element in mock circulation may be helpful for investigating heart valves

Apoptosis - Mitochondrial pathway may be involved in myocyte apoptosis in the heart

Apoptosis - NF-kappa B activation by API2/MALT1 fusions inhibits p53 dependant apoptosis

Apoptosis - SOD and/or IL-10 may decrease hyperoxic lung injury by decreasing apoptosis

Arterial Occlusion - Safety and efficacy of subintimal angioplasty reviewed

Aspergillosis - CpG oligodeoxynucleotides modulate airway inflammation in aspergillosis model

Assisted Reproduction - Poland: Multiple embryo implantation blamed for high neonatal mortality in ART

Asthma - Female sex, education and income levels are risk factors for hospitalization

Asthma - Neighborhoods near heavily traveled border crossings have high asthma incidence

Asthma - Patients experience asthma variability, despite strict adherence to guidelines

Asthma - QVAR in patented Easi-Breathe inhaler launches in United Kingdom

Asthma - Skin tests important in severe asthma patients

Asthma - Study: Inhaled corticosteroid use not cause of higher fracture risk in children

Astronomy - "Dark" hydrogen found

Atherosclerosis - Estrogen-associated COX-2 pathways may explain heart disease protection

Atherosclerosis - Metalloproteinases could influence arterial remodeling in hemodialysis patients

Atopic Disease - Epinastine hydrochloride is marketed as having few CNS-depressant side effects

Atrial Arrhythmia - Incidence and effects of for-field R wave oversensing in implants determined

Atrial Flutter - Chronic atrial flutter is marked by prolonged counter-clockwise conduction times

Atrophic Vaginitis - Vaginal dryness can be treated for menopausal women who suffer from condition

Autism - Evaluation of early intervention in autism

Autoimmune Diabetes - Diabetes is prevented when costimulatory molecules are down-regulated in mice

Autoimmune Diseases - IRH data presented at International Congress on Autoimmune Diseases

Autoimmune Hemolytic Anemia - High incidence of autoimmune hemolytic anemia complicating SCT in children

Autonomic Responses - Heat stress does not modify the vestibulosympathetic reflex

Avian Influenza - Domestic ducks could pose new avian influenza threat

Awards - Aetna Group Insurance presents award for excellence in research

Awards - Arc of Dauphin & Lebanon Counties names Highmark Blue Shield employer of year

Awards - Cancer reference laboratory named to Deloitte's Fast 500 list

Awards - Fluid diagnostics company receives award

Awards - Generic drug maker named Best Overall Pharmaceutical Products Manufacturer

Awards - Hematologist receives prestigious NIH merit award

Awards - Patient monitoring system wins Innovations 2005 Design and Engineering Honors

Awards - Scott Hawley named American Cancer Society research professor, awarded $300,000

Awards - Technology Council names biotech company early stage company of the year

Bacteremia - Enrollment complete for Cubicin's phase III endocarditis/bacteremia trial

Bacterial Isolation - Enterobacteriaceae isolated from powdered infant milk formulas

Bacteriology - Community living causes bacteria to diversify

Behavior - Amount of violence in nursery rhymes 10 times greater than British TV

Behavior - Good intentions vs. bad habits: why the old ways win out

Beta Blockers - PF9404C and nitroglycerin show different profiles in causing vasodilation

Biological Therapies - Plasma elements deem VEGF a biomarker for intestinal cancer transformation

Biological Therapy - Type-1 innate and acquired immunity play crucial roles in tumor immunotherapy

Biotechnology - CRO names VP of project management, Joseph Parks

Biotechnology - Copolymer microsphere system devised for amino acid seperation

Biotechnology - Pharma companies will look to public institutions for productivity help in 2005

Birth Defects - Folic-acid supplementation can prevent 70% of spina bifida cases

Bladder Cancer - Promising data presented on phase 2 trial drug for superficial bladder cancer

Blood Pressure - Lipopolisaccharide treatment leads to down-regulation of cholinergic connections

Blood Safety - Anti-infective technologies company receives NASDAQ noncompliance notification

Blood Testing - Automated blood tests faster, safer

Bone Density - Depo-Provera adds black box warning about bone density loss

Bone Marrow Storage - Glycerol plus polyvinylpyrrolidone optimally preserves frozen bone marrow cells

Bone Marrow Transplantation - Novel technique isolates/tracks rare lymphoid stem cell that facilitates BMT

Bone Neoplasms - Trisacryl gelatin microspheres effective for preoperative embolization

Brain Cancer - Post-therapy damage in medulloblastoma patients can be mistaken for new tumors

Brain Injury - Neuro-monitoring system to measure cerebral blood flow to launch

Breast Cancer - "Knowledge management" system could "revolutionize" treatment

Breast Cancer -  GATA3 mutations identified in breast tumors

Breast Cancer - Accelerated partial breast irradiation new option for breast cancer patients

Breast Cancer - Apoptotic response of tamoxifen-resistant breast tumor cells clarified

Breast Cancer - Breast cancer study examines new radiofrequency ablation assisted lumpectomy

Breast Cancer - Chemotherapies have varied effects on menopausal symptoms of cancer patients

Breast Cancer - Data on radiation dose from digital mammography reported from large study

Breast Cancer - Elizabeth Edwards's diagnosis encourages others to get check-ups

Breast Cancer - Endogenous BRCA1-IRIS may influence DNA replication initiation machinery

Breast Cancer - Enhancing cancerous area on MR mammography compared with pathological exam

Breast Cancer - Genes linked to breast tumor progression and/or metastasis identified

Breast Cancer - HER2-positive disease invades organs due to fatal chemical attraction

Breast Cancer - Hierarchical clustering of breast tumor immunomarkers has high prognostic value

Breast Cancer - In BRCA1/2 mutation carriers, cancer may mimic benign lesions on mammogram

Breast Cancer - New surgical technique determines if cancer has spread

Breast Cancer - Obesity, lymph node status, and prognosis in breast cancer explored

Breast Cancer - Patients receiving taxane-based chemotherapy not at higher risk of pneumonitis

Breast Cancer - Phage display library from lymph nodes of breast cancer patients constructed

Breast Cancer - Plasma prolactin levels associated with increased postmenopausal disease risk

Breast Cancer - Private practice in Munich, Germany, selects mammography system

Breast Cancer - Saudi Arabia: National guidelines on breast cancer management needed

Breast Cancer - Topoisomerase II alpha is a prognostic indicator in breast cancer

Breast Cancer - Trial evaluates supplemental screening sonography in dense breasts

Breast Cancer - Women willing to deal with negative aspects of screening to gain benefit

Breast Enlargement - Plastic surgeons: Breast enhancement pills unlikely to work, could be dangerous

Business & Finance - Biopharma reports third quarter 2004 results, clinical achievements

Business & Finance - Biopharmaceutical company reports third quarter financial, operating results

Business & Finance - Biopharmaceuticals company announces third quarter results, progress made

Business & Finance - Biotech company announces restructured agreement for cancer drug

Business & Finance - Biotech company reports loss of $0.03 per share

Business & Finance - Company reports Q3 results, provides MS-325 regulatory update

Business & Finance - Company reports increase in income and revenue; discusses Inveresk merger

Business & Finance - Company reports third quarter results, Chrysalin product activities

Business & Finance - Dermatology pharmaceutical company announces financing, new hires

Business & Finance - Developer of surgical and diagnostic products announces financial results

Business & Finance - Imaging services company reports on acquisition, EMR software development

Business & Finance - Managed care company announces third quarter results up 261%

Business & Finance - Microcatheter systems developer receives notice from Nasdaq regarding bid price

Business & Finance - Newborn health company reports third quarter revenue and earnings

Business & Finance - Pharmaceutical company reports fourth quarter loss of $0.28 per share

Business & Finance - Pharmaceutical firm reports loss of $0.18 per share

Business & Finance - Prochieve maker provides Q3 report, updates PROTERM study

Business Trends - Pharmaceutical sector looks to improve cash management and reduce risk

Business Update - ARICEPT maker launches marketing sub in India

Business Update - BIOPRO expands sales force into Australia

Business Update - Biotech establishes new business units for pain and oncology

Business Update - Biotechnology company enters strategic marketing agreement with Body Blue

Business Update - Bristol-Myers Squibb carries out promised job cuts

Business Update - Celgene shares slide on report of patient deaths during drug test

Business Update - ComfortScan agreements inked in Canada, Italy, and Russia

Business Update - Company raises over $25M, announces CCP Worldwide merger

Business Update - CryoCath enters exclusive global partnership

Business Update - Defibrillator maker ranked as fourth fastest growing technology company

Business Update - Dendrite inks reseller agreement

Business Update - Digital radiography technology company signs OEM agreement in Spain

Business Update - Dow invests in new facilities to support Asia growth

Business Update - European drug developer awards $1.4M study to ECG services company

Business Update - Examinetics completes move to new corporate headquarters

Business Update - Healthaxis signs contract with informational service company

Business Update - Hundreds rally to save troubled Los Angeles County hospital's trauma unit

Business Update - IPC to provide ER coverage, inpatient hospitalist services at Illinois hospital

Business Update - IPRO to perform reconsiderations of denied Medicare fee-for-service claims

Business Update - IUN and Theragenics Corporation sign 3-year strategic alliance agreement

Business Update - Indian hospital plans cuts in Albuquerque clinic

Business Update - Invacare signs exclusive technology/economic agreement with Vyatek Sports

Business Update - Marketing contract announced for Secure Balance, wireless gas alarm products

Business Update - Molecular diagnostics company announces expansion of diagnostic pipeline

Business Update - New company to develop, produce patient-specific cancer vaccines

Business Update - Patient recruitment firm reports 33% increase in patient panel

Business Update - Pharmacy services provider selects regulation solution, acquires pharmacy

Business Update - Provider of microfluidic analytical systems announces sales partnership

Business Update - Siemens and Holy Redeemer Health System enter 10-year agreement

Business Update - Sigma-Aldrich catalog, safety data available in integrated software database

Business Update - Two West Virginia hospitals seek permission for outpatient surgery

Cancer Genetics - BRCA1 missense variant thwarts transcriptional activity

Cancer Genetics - Clinical studies needed to evaluate role of BRCA1 in chemotherapy response

Cancer Genetics - SOCS1 and 2 genes suppress growth of ovarian and breast carcinoma cells

Cancer Immunoprevention - Fused cell vaccination and CpG oligodeoxynucleotides reject tumor recurrence

Cancer Management - Standardized reviews of glioblastoma vascular patterns assist treatment choice

Cancer Research - Vascular targeting agent, radiation reduces tumor growth by 98% in animals study

Cancer Risk Factor - Hepatitis C infection encourages liver cancer recurrence after resection

Cancer Screening - OC Auto Micro 80 analyzer detects blood in stool samples

Cancer Screening - Program to implement required Pap interpretation proficiency testing announced

Cancer Suppression - p21Waf1 gene transfer via gene gun technology limits esophageal cancer growth

Cancer Therapy - European cancer organization offers guidelines for treating anemia

Cancer Therapy - Radiation therapy systems selected to supply Wave 7 of UK Cancer Plan

Cancer Therapy - Skin cancer study using MedPulser Electroporation Therapy system begins

Cancer Therapy - VELCADE gets fast track status for relapsed and refractory mantle cell lymphoma

Cancer Vaccine -  Listeria-based cancer vaccines segregate immunogenicity from toxicity

Cancer Vaccine - Dendritic cells boost antitumor activity of adoptively transferred T cells

Cancer Vaccine - Expression of the cell surface mucin gene family in adenocarcinomas reported

Cancer Vaccine - IL-13 antagonist and Pseudomonas toxin fusion protein is anticancer

Cancer Vaccine - Tumor vaccine therapy reviewed

Cancer Vaccines - Interleukin-15 transfection plus CD8+ T cells cause colon cancer rejection

Cardiac Arrhythmias - Eligible women less likely than men to receive implantable defibrillators

Cardiac Arrhythmias - Freezor MAX obtains FDA approval in the U.S.

Cardiac Care - Montgomery County, Maryland, to require defibrillators in health clubs

Cardiac Energetics - Review focuses on transgenesis and cardiac energetics

Cardiac Markers - Regression equation can provide guidance on equivalence between cardiac markers

Cardiac Myocites - Technique may represent a novel therapeutic strategy for heart failure

Cardiac Myocytes - Scientists have discovered several novel potent NCX inhibitors

Cardiac Research - Enzyme, inflammation have role in formation of vulnerable plaque, study shows

Cardiac Surgery - Low adverse events incidence with sirolimus-eluting coronary stent, study shows

Cardiology -  Mef2c gene is a direct target of Foxh1 transcription factor

Cardiology - Burn trauma may contribute to cardiac contractile dysfunction

Cardiology - Changes in isozyme activities, CaM concentration may affect muscle contractility

Cardiology - Company says implantable defibrillators are cost-effective treatment for heart failure patients

Cardiology - Company updates preclinical findings for synthetic vascular graft

Cardiology - Findings may provide insight into long-term effects of alpha1 -AR antagonists

Cardiology - Microvolt T-wave alternans tested in non-ischemic patient population

Cardiology - PTH1R-mediated mechanisms may protect against CV stress-induced responses

Cardiology - Pharmaceutical company announces results of heart disease risk study

Cardiology - Pharmaceutical company comments on results of coronary artery disease study

Cardiology - Pharmaceutical company reports on atherosclerosis clinical trail

Cardiology - Research shows generic statin drugs produce same results as brand-name counterparts

Cardiology - Review summarizes advances made on the regulation of cardiac ion channels

Cardiology - Review summarizes knowledge about arrhythmic disorders that cause sudden death

Cardiology - Selective delipidation process used to help remove cholesterol from cells

Cardiology - Simultaneous activation of JNK and p38 by MLK7 may affect cardiac decompensation

Cardiology - Study shows benefits of blood pressure treatment

Cardiology - Study shows differences in cardiovascular risk among cox-2 inhibitors

Cardiology - Superoxide dismutase activity was enhanced in the heart cytosol of rats

Cardiology - Tethering of protein kinase A may be essential for cardiac muscle contraction

Cardiology - TnT may contribute to the higher tolerance of slow muscles to stress conditions

Cardiology - Xenon anesthesia impairs partial rebreathing-based cardiac output assessment

Cardiology & Renal Disease - Atorvastatin is safe, effective for dyslipidemia in hemodialysis patients

Cardiopulmonary Bypass - Postoperative fibrinolysis in pericardial cavity characterized

Cardiovascular Care - WonderLab museum exhibit alerts mom to son's heart condition

Cardiovascular Devices - Non-critical pacemaker-induced interference in video capsule endoscopy reported

Cardiovascular Devices - Thrombogenic effects of novel continuous flow axial pump determined

Cardiovascular Disease - Addition of INTEGRILIN provides superior platelet inhibition with stenting

Cardiovascular Disease - Angiotensin II-responsive genes identified in adrenocortical cells

Cardiovascular Disease - Data confirms enzyme's potential as a target for cardiovascular diagnosis

Cardiovascular Disease - Nanobacterial link to abnormal calcification described in newly released book

Cardiovascular Disease - Protein is an independent risk marker for kidney and cardiovascular disease

Cardiovascular Disease - Utility of drug-eluting stents reviewed

Cardiovascular Diseases - Study analyzes weather patterns and hospitalizations

Cardiovascular Health - Walnuts show multiple new heart health benefits

Cardiovascular Regulation - Urantide should be considered a low efficacy partial agonist

Cell Biology - Biopharma company's cell cycle inhibitor work published in Science

Cell Biology - By impounding iron, FHC foils cell suicide, fuels inflammation

Cell Biology - Mechanisms of chaperone-mediated autophagy reviewed

Cell Biology - Microarray-based high-throughput telomerase assay developed

Cell Biology - Millennium, German pharma will work together on cell line development

Cell Biology - New evidence found for cancer stem cells

Cell Biology - New tool highlights activity of key cellular signal

Cell Biology - Scientists uncork fountain of youth for HIV-fighting cells

Cell Biology - Sec15 acts as effector for Rab11 GTPase

Cell Biology - Single water molecule acts as gate keeper

Cell Research - Amino acid fluxes have a role in long-term volume regulatory processes

Central Nervous System - Deep brain stimulation introduced as treatment of neurological disorders

Central Nervous System - Phase 2 attention deficit hyperactivity disorder study completed

Cerebral Palsy - Gross mechanical efficiency can be used to evaluate changes in motor function

Cervical Cancer - Chemoradiation with gemcitabine an alternative for patients with renal failure

Cervical Cancer - Clinical trial investigates food supplement's preventive effects

Cervical Cancer - HPV 16 infection a risk factor for disease progression in younger women

Cervical Cancer - Small cell neuroendocrine carcinomas of the uterine cervix characterized

Cervical Cancer - Study says Ireland's high death rate is due to lack of screening program

Cervical Cancer - Study: Shorter, more aggressive treatments better control disease

Chemoresistance - Interleukin-1 beta-mediated blast survival may contribute to chemoresistance

Chemotherapy - IMPAC announces support for CMS quality of care assessment in chemotherapy

Childhood Obesity - Four Osceola County, Florida, schools use South Beach Diet for student lunches

Childhood Obesity - Kentucky lawmakers consider options for dealing with child obesity

Childhood Obesity - Magazine spotlights Fairhope, Alaska, teacher's fight against child obesity

Cholera Vaccine -  Vibrio cholerae amino acid sequence induces protective antibodies

Chronic Lymphocytic Leukemia - Primary endpoint achieved in phase 3 trial of genasense plus chemotherapy

Chronic Obstructive Pulmonary Disease - COPD afflicts three times the number of adults than previously estimated

Chronic Obstructive Pulmonary Disease - Corticosteroids are effective in reducing serum CRP levels in patients with COPD

Chronic Obstructive Pulmonary Disease - Smoking cessation can improve survival among severe COPD patients, study shows

Claims Processing - FCG launches FirstPAS, hosted solution to automate claims pends

Climate Change - Grape-picking records help scientists learn about warming trends

Climate Change - Tropical birds sensitive to environmental cues that affect breeding

Clinical Trials - Report: Clinical trial inefficiencies cost drug companies millions

Cochlear Implants - Role of spectral and temporal cues in voice gender discrimination clarified

Cognition - Immunization may have long-term effects on cognitive performance

Cold Autoinflammatory Syndrome - Study yields effective treatment for fever syndrome caused by cold exposure

Colitis - Ulcerative colitis product report receives gastroenterology society award

Collaborations - Aetna signs contract with Baptist Health Services

Collaborations - Affitech, Peregrine expand collaboration to develop new fully human antibodies

Collaborations - Agreement signed to codevelop Tandabs

Collaborations - Anti-cancer vaccine R&D agreement signed

Collaborations - Biopharma delivers candidate, achieves research milestone with Organon

Collaborations - Biopharma, consortium collaborate to treat brain cancer patients

Collaborations - CROs announce strategic partnership agreement

Collaborations - Companies combine technologies to search for cancer-fighting compounds

Collaborations - Companies introduce solid support product for manufacture of oligonucleotides

Collaborations - DNA sequencing company enters into strategic partnership with SeqWright

Collaborations - DNA-based diagnostics company, biotech products provider announce partnership

Collaborations - Diagnostics company, Vanderbilt combine fluorescence reader, lab-on-chip assays

Collaborations - Dyax announces antibody discovery collaboration

Collaborations - Global deal signed for surgical cryotherapy treatment for atrial fibrillation

Collaborations - Manufacturing agreement signed for pharmaceutical siRNA

Collaborations - Nanotechnology companies ink broad cross-licensing pact

Collaborations - Nonprofit tissue banking organizations form partnership to benefit community

Collaborations - Phage display license added to company's genes-to-electronics portfolio

Collaborations - PharmaCare selected as preferred PBM

Collaborations - Pharmaceutical companies enter collaboration to develop digestive enzymes

Collaborations - Research software deal signed for new materials characterization software

Collaborations - Service agreement signed with Lexicon Pharmaceuticals

Colon Cancer - ELOXATIN approved for colon cancer treatment following surgery

Colon Cancer - Genetic markers of tumorogenic aberrant crypt foci identified

Complementary & Alternative Medicine - Tennessee Senator plans to make legal medical marijuana a top priority

Complementary and Alternative Medicine -  Agaricus blazei extract halts cancer and metastasis in tumor models

Complementary and Alternative Medicine - Defibrillator discharge reported after consuming weight loss supplement

Complementary and Alternative Medicine - Pediatricians wary about recommending complementary therapies

Compliance - Cleveland Clinic selects Sentillion to help meet authentication compliance

Compliance - Non-compliance reported to cause 125,000 hospital, nursing home deaths annually

Compliance - Visually impaired find medicine labels, information too small to read

Computerized Tomography - Medical device company installs 64-slice CT scanner at Boston medical center

Congestive Heart Failure - Congestive heart failure survival associated with 2 sets of diagnostic criteria

Congestive Heart Failure - Implanted defibrillators cut heart patients' death risk

Congestive Heart Failure - Uncoupling proteins may cause emergency deficiency in human heart

Consumer-Driven Healthcare - Elan to process cards for HealthEquity's HSAs

Consumer-Driven Healthcare - Great-West Healthcare teams with Mellon Financial to launch HSA

Consumerism - Poll: Consumers doubt bonus pay will improve physician performance

Contraception - Clinical testing of transdermal contraceptive spray begins

Coronary Artery Bypass - Additional results reported from phase III PRIMO-CABG trial

Coronary Artery Bypass - Aprotinin reduced bleeding in bypass surgery patients on anti-platelet drugs

Coronary Artery Disease - Data on coronary artery disease presented at AHA sessions

Coronary Artery Disease - Evaluate C. pneumoniae IgG antibodies in cases of coronary artery disease

Coronary Artery Disease - Norvasc study reports fewer major CV events in coronary artery disease patients

Coronary Artery Stenosis - Renin-angiotensin system is associated with forming of coronary artery stenosis

Correctional Health - Inmates trained to assist prison nurses in new state program

Crohn Disease - Crohn disease study published in leading journal

Crohn Disease - Lipoxin may provide a promising new oral treatment for Crohn disease

Crosslinking - SR proteins involved in export of general intronless and spliced mRNAs

Cryptococcus Outbreak -  Cryptococcus neoformans outbreak at Vancouver Hospital between 1997-2002

Cryptococcus Vaccine - Immunoglobulin against Cryptococcus glucuronoxylomannan is protective

Cystic Fibrosis - Research with red tide toxin yields potential therapies for lung disease

Cytomegalovirus - CMV UL84 insertion mutant is defective for viral DNA synthesis and growth

Cytomegalovirus - Cytomegalovirus inhibits cytokine-induced macrophage differentiation

DNA Analysis - A novel method estimates allele frequencies in pooled DNA samples

DNA Vaccine - DNA vaccines induce epitope-specific CTLs against histocompatibility antigens

Dementia - Challenging jobs lessen risk of dementia

Dementia - Frequent hospital admission for depression may increase risk of dementia

Dengue Virus - Dengue viral infections reviewed

Densitometry - Dosimetric properties of improved GafChromic films characterized

Depression - Brain's nicotine receptors also target for antidepressants

Depression - Common antidepressant may affect youths' bone development

Depression - Electroconvulsive therapy feasible in patients with implanted cardiac devices

Depression - Survey finds global rise in antidepressants prescribed to children

Dermatology - T-oligos trigger anticancer activity in melanoma cells

Development - Triplets not as cognitively advanced at 1 year as singletons, twins

Developmental Biology - Researchers discover molecular timekeeper in bone development

Developmental Neurology - Intrauterine infection can cause increased Th1 cytokine levels in fetal brain

Diabetes - Company presents data supporting early detection of diabetic retinopathy

Diabetes & Hypertension - Diabetics with hypertension may benefit significantly from a newer beta-blocker

Diabetes Complications - Carnitine deficiency found in children with type 1 diabetes

Diabetes Genomics and Genetics - ABCG5 and ABCG8 gene polymorphisms linked to insulin sensitivity

Diabetes Genomics and Genetics - HFE gene linked to diabetic nephropathy in type 2 diabetes

Diabetes Genomics and Genetics - Pathogenic Delta mtDNA induced deafness but not diabetic phenotypes

Diabetes Pathogenesis - Calpain-related diseases reviewed

Diabetes Pathogenesis - Ceramide synthesis and protein kinase C play role in insulin resistance

Diabetes Pathogenesis - Diabetogenic T cells escaping near death have enhanced pathogenicity

Diabetes Pathogenesis - Enzyme-to-enzyme channeling in glycolysis in pancreatic islets examined

Diabetes Pathogenesis - Expression of TREK-2 in insulin-secreting MIN6 cells described

Diabetes Pathogenesis - IL-1 reduces fusion of insulin granules in pancreatic beta cells

Diabetes Pathogenesis - Immunokinetics of autoreactive CD4 T cells in blood reviewed

Diabetes Pathogenesis - Insulin resistance changes amino acid metabolism in diabetic fatty rats

Diabetes Pathogenesis - Insulin resistance prevented by inhibition of nuclear factor kappa B

Diabetes Pathogenesis - Mild nephrogenic diabetes insipidus caused by Foxa1 deficiency

Diabetes Pathogenesis - Role of caveolae and caveolins in health and disease reviewed

Diabetes Pathogenesis - Src tyrosine kinase regulates insulin-induced protein kinase C delta

Diabetes Research - Atomic structure of enzyme HSD-1 reported, use in diabetes treatment studied

Diabetes Therapy -  Nigella sativa extract exerts insulin-sensitizing action

Diabetes Therapy -  Psidium guajava extract exerts hypoglycemic effect in diabetic rats

Diabetes Therapy - Bis(quercetinato)oxovanadium(IV) conjugate is insulin enhancing

Diabetes Therapy - Insulin-releasing substance isolated from Gynostemma pentaphyllum

Diabetes Therapy - Novel substrates with insulin-like activity identified

Diabetes Therapy - Therapy of patients with diabetes and advanced kidney disease reviewed

Diabetic Cardiomyopathy - Left ventricular function impaired in elderly with type 2 diabetes

Diabetic Cardiomyopathy - Regulation of aminopeptidase in cardiomyocytes examined

Diabetic Nephropathy - ACE inhibitor/diuretic combination protects obese rat kidneys

Diabetic Nephropathy - Early onset of cisplatin nephrotoxicity reported in diabetic rats

Diabetic Nephropathy - Tranilast reduces mesenteric vascular collagen deposition in diabetes

Diabetic Neuropathy - Diabetic neuropathy accelerated in axons without neurofilaments

Diabetic Retinopathy - Cyclooxygenase-2 inhibition lowers prostaglandin levels in diabetic rat retinas

Diabetic Retinopathy - Prorenin levels linked to microvascular complications in diabetes

Diagnostic Imaging - Computed tomography can identify HSV-related hepatitis in pregnant women

Diagnostic Imaging - Medical technology company releases new diagnostic ultrasound system

Diagnostics - Diagnostics products company announces reagent for common respiratory viruses

Diagnostics - Indian pharmaceutical company launches new cancer diagnostic product

Diagnostics - Multiplex RT-PCR assay detects balanced translocations in leukemia patients

Diagnostics - Novel chemiluminescent immunosensor assay detects serum CA19-9 levels

Diagnostics - Nuclear imaging offers possibility for early detection of heart disease

Diagnostics - Protocol for evaluation of oral fluid collectors developed

Diagnostics - Real-time PCR with FRET probes genotypes HLA-B27 faster than other methods

Diagnostics - Universal microarray detects the severe acute respiratory syndrome coronavirus

Diet and Nutrition - Grapefruit juice has anticlastogenic effects in mice

Diet and Nutrition - Women in study ate 800 fewer calories daily and were satisfied

Dietary Supplements - Nature Made vitamin maker calls for balanced reporting on vitamin E analysis

Diphtheria Vaccine - Respiratory epithelial cells internalize Corynebacterium diphtheriae

Disease Associations - Childhood trauma and dissociative experiences in OCD/TTM patients are linked

Disease Associations - Genetics of HLA-associated disease reviewed

Disease Associations - New study addresses link between protein folding and factory construction

Disease Associations - Tissue expression of IL-18 may be associated with the pathogenesis of GVHD

Disease Associations - Venesection improves bilirubin in a Dubin-Johnson syndrome and hepatitis C case

Disease Investigation - Low tissue factor mice offer a way to study hemostasis and vascular integrity

Disease Management - BlueCross BlueShield of Tennessee to use predictive modeling solution

Disease Prevention - African leaders, health activists push for money to fight disease

Disease Prevention - Communicable disease treatment exempt from Proposition 200

Disease Prevention - Global health alert network now scans for disease reports in seven languages

Disease Prevention - Lack of reliable death tolls worldwide makes curing the sick even tougher

Disease Prevention - Women often neglect health when prevention is most important

Disease Transmission - Case of vertically transmitted HSV-2 infection resembled calcified myocarditis

Doctor Incentives - Businesses, insurers offering incentives to doctors, hospitals

Drug Delivery - Celecoxib-loaded chitosan microspheres effective for joint delivery

Drug Delivery - Kinetics of paclitaxel release from blended-polymer microspheres evaluated

Drug Delivery - Microvolumetric pump improves continuous drug infusion

Drug Delivery - Novel agent enhances colon drug delivery

Drug Delivery - Pharmaceutical company announces distribution agreement in Korea

Drug Delivery - Promising study results presented for Captisol

Drug Delivery - Pullulan nanoparticles transport drugs and genes into cells

Drug Delivery - Rapid release tablet formulation of micronized danazol powder developed

Drug Delivery - Research agreement forged to study nasal delivery for diabetes and Alzheimer

Drug Delivery - Sugary ingredients help Olive Branch pharmacy make the medicine go down easier

Drug Development - Autoradioluminography useful to find tritium-labeled drug candidates

Drug Development - Bristol-Myers expects to file two additional new drug applications by year end

Drug Development - Cervical cancer's image as a niche market hinders drug development

Drug Development - Dietary fiber supplement can reduce drug use for high cholesterol, study shows

Drug Development - Elderly cancer patients significantly underrepresented in cancer trials

Drug Development - Immunosuppressant to enter clinical trials

Drug Development - Native American project: increasing access to clinical trials

Drug Development - New partnership for high performance drug discovery announced

Drug Development - Novartis picks drug for development from protein kinase research collaboration

Drug Development - Phase I thought leader involvement pays off

Drug Development - Two outsourcing specialists announce new partnership

Drug Development - U.S. company to test use of obesity/smoking pill for heart disease

Drug Development - WHO develops priorities for drug research, including expected flu vaccines

Drug Discovery - Drug discovery company announces new technology for targeting proteins

Drug Dispensing - Robotic dispensing system to support Kerr vials

Drug Handling - CyTwo-Fer Needle launched for safe reconstitution of hazardous drugs

Drug Therapy - Hyperpolarization and relaxation decline with hypertension and aging

Drug Therapy - Proarrhythmia is a potentially dangerous side effect of drug therapy

Drug Therapy - Study examines the interactions of atorvastatin and sildenafil

Dysmenorrhea - High stress doubles risk of painful periods

Ebola Virus - Disulfide bonds of Ebola-virus-secreted glycoprotein SGP assigned

Echocardiography - Medical device company introduces echocardiography systems at AHA sessions

Echocardiography - Transesophageal ECG allowed for reliable monitoring of segmental wall motion

Education - Geisinger consolidates compliance training with Pathlore

Electrocardiography - Electrocardiography has evolved to a mainstay of cardiovascular medicine

Electronic Medical Records - Bloomington Hospital selects McKesson to build electronic health record

Embryogenesis - GRIM-19 is essential for assembly and function of mitochondrial complex I

Embryonic Stem Cell Research - 5-Azacytidine reverses differentiation of embryonic stem cells

Embryonic Stem Cell Research - Core enhancer regulates gene expression in embryonic and neural stem cells

Embryonic Stem Cells - Microscopy technique characterizes growth stages of embryonic stem cells

Emergency Medicine - Patients who are intubated prior to hospital arrival fare worse

Emergency Medicine - Urban hospitals bear the brunt of motorcycle injuries

Emotional Health - Posture found to communicate fear

Encephalomyelitis - ICAM-1 upregulation in allergic encephalomyelitis depends on TNF-alpha

Endangered Species - Family ties give hope to beat butterfly blues

Endocrinology - Alpha1 -adrenergic receptor subtypes differentially regulate cell cycle

Endocrinology - Estrogen uses PAF-mediated NF-kappaB to stimulate angiogenesis

Endometriosis - Recent advances in endometriosis highlighted

Environmental Health - U.S. Army developing plan to burn buildings with toxins

Environmental Health - Updated government study finds mercury levels in women, children 'not a concern'

Environmental Toxins - Effects of ozone on mortality in 23 European cities

Environmental Toxins - Government group to develop new RNAi library to help fight disease

Environmental Toxins - Safety of bismuth bullets questioned

Enzyme Immunoassays - Enzyme immunoassay tests to detect Mycoplasma antibodies assessed

Enzymology - A novel in vitro assay measures the cleavage efforts of DNA repair enzyme

Enzymology - Cyclooxygenase-2 supports angiogenic growth in malignant fibrous histiocytomas

Enzymology - Lipophilicity influences polyphenol interactions with CYP3A4

Enzymology - Monomeric CYP 3A4 characterized in nanoscale membrane bilayer

Enzymology - PinX1 may regulate telomere length in human hepatocellular carcinoma

Epilepsy - Size of seizure-inducing epileptic foci elucidated

Erectile Dysfunction - Female sexual function improves with treatment of male partner

Evolutionary Biology - Jogging drives evolution

Exercise - UCP3 gene -55 C/T polymorphism not linked to athletic performance

Exercise Stress Testing - Review examines the prognostic value of cardiopulmonary exercise stress testing

Eye Disease - New study reaffirms progress toward eliminating blinding trachoma

Facial Deformities - Foundation helps fund surgery, care for children with facial deformities

Facilities - Univ. of South Dakota students will help cover cost of new med school building

Finance - Allergy company announces significant debt-to-equity conversion

Finance - Behavioral health services provider reports record revenue for first quarter

Finance - Biological products developer announces first quarter fiscal 2005 results

Finance - Biological technology company reports pleasing first quarter results

Finance - Biomaterials company reports third quarter results

Finance - Biopharm company focused on protein-deficiency disease reports Q3 results

Finance - Biopharmaceutical company announces reduction of net loss in third quarter

Finance - Biopharmaceutical company announces third quarter 2004 financial results

Finance - Biopharmaceutical company reports third quarter 2004 results

Finance - Biopharmaceutical company reports third quarter financial results

Finance - Biopharmaceutical firm reports income of $0.17 per share

Finance - Biotech company focused on immune system disease reports Q3 2004 financials

Finance - Biotech company reports loss of $0.15 per share

Finance - Biotech company reports loss of $0.17 per share

Finance - Biotech firm raises $7.3M in series B financing

Finance - Biotechnology company closes private placement for $940,500

Finance - Biotechnology company reports improved third quarter results

Finance - CDN $6.9M funding available for 16 projects from cancer to heart disease

Finance - Canadian biotech enters into a bought deal financing for $10 million

Finance - Cardiac device firm reports 19% revenue increase

Finance - Caremark announces strong third quarter results, raises guidance for 2004

Finance - Chemed declares quarterly dividend of 12 cents

Finance - Compliance software provider reports third quarter 2004 financial results

Finance - Contract research, development firm reports record revenues, profitability

Finance - Cytyc announces investment in endometriosis-focused company

Finance - Daou Systems reports 44% increase in net losses during Q3

Finance - Dermatology drug maker reports loss of $0.47 per share

Finance - Developer of medical devices reports third quarter financial results

Finance - Device firm reports 67% increase in sales of Kidz-Med products

Finance - Device firm reports net earnings tripled on 19% revenue gain

Finance - Diagnostics company releases third quarter financial results

Finance - Diagnostics company reports 34% increase in Q1 revenues

Finance - Diagnostics company reports 8% increase in revenues

Finance - Diagnostics firm reports net earnings growth of 43%

Finance - Digital imaging technologies company reports fiscal 2005 Q2 results

Finance - Disease management company announces terms of proposed private share placement

Finance - Drug discovery company announces improved third quarter results

Finance - Drug discovery company reports income of $0.09 per share

Finance - EMS company reports Q1 revenue up 13% to $21.7 million

Finance - Endocrine-focused biopharmaceutical company reports third quarter financials

Finance - Essure maker reports on Q3; year-to-date net sales up 47%

Finance - European therapeutics company reports interim results for first 9 months 2004

Finance - Eye care company reports Q3 and Q4 financials

Finance - First Health provides Q3 update, reports dip in income

Finance - Former controlling shareholder sells pharma's common stock

Finance - Functional somatic syndomes-focused company announces Q3 income of $376,000

Finance - GLIADEL Wafer maker reports Q3 net loss of $14.5 million

Finance - GR-system developer reports Q3 net loss of $6.7 million

Finance - Ganite maker announces Q3 revenues of $1.4 million

Finance - Genetic analysis company reports 190% increase in product sales in Q3

Finance - Ginseng supplier reports increased revenue in Q3

Finance - Grants awarded for antibody research related to angiogenesis

Finance - HFC announces 76.7% increase in third-quarter results

Finance - Hospital system reports fiscal 2005 first quarter results, updates acquisitions

Finance - INTERCEPT maker reports Q3 revenue of $3.5 million

Finance - Imaging systems provider reports 22% increase in fourth quarter revenues

Finance - Immune-focused company announces Q3 net loss of $4M

Finance - Immunoassay maker reports 18.5% decrease in net sales

Finance - Integrated systems biology company announces increase in third quarter revenues

Finance - Investment research firm announces opinion on physician practice management company

Finance - Japanese pharmaceutical company announces continued financial growth

Finance - Lab chip maker reports quarterly loss of $0.17 per share

Finance - Life science products company reports revenue growth of 37% in third quarter

Finance - Life sciences company reports 26% increase in third quarter revenues

Finance - Life sciences-focused biotech company declares quarterly cash dividend

Finance - Long-term care company reports quarterly results, sale of medical supply firm

Finance - Managed care company reports 21st consecutive quarter of increased profitability

Finance - Market research budgets rise as drugs reach phase II testing

Finance - Medical device company reports 38% increase in sales

Finance - Medical device firm reports agreement for $8M private placement

Finance - Medical device venture capital firm closes on $55M fund

Finance - Medical diagnosis and therapy systems company reports 9-month results

Finance - Medical diagnostics company reports 34% revenue increase over third quarter

Finance - Medical imaging company reports third quarter financial results

Finance - Medical manufacturing company reports 78% increase in third quarter sales

Finance - Medical research company reports 14% increase in net sales during first quarter

Finance - Microalgae company reports Q2 sales of $2,998,000, net income of $121,000

Finance - MyVax maker announces Q3 net loss of $6.7 million

Finance - Neurotherapeutics company raises CDN$6 million in series A financing

Finance - NeutroSpec maker reports first quarter fiscal year 2005 results

Finance - Nutrition supplements company reports first quarter fiscal 2005 results

Finance - Nutritional supplements company retains firm for investor relations support

Finance - Offer made to skin care company shareholders to raise funds for clinical trials

Finance - Oncology company adopts stockholder rights plan

Finance - Oncology company announces effectiveness of S-3 Registration Statement

Finance - Oncology company receives approval for AMEX listing

Finance - Oncology-focused biopharmacology company reports third quarter financials

Finance - Ophthalmic company reports improved third quarter financial results

Finance - Optics company announces first quarter results

Finance - Orthobiologics company reports 9% increase in third quarter sales

Finance - PainCare reports third quarter results, 2005 guidance

Finance - Personal products, nutrionals company declares quarterly dividend of $0.08

Finance - Pharmaceutical company announces U.S. expansion

Finance - Pharmaceutical company announces pricing of stock offering

Finance - Pharmaceutical company announces stock repurchase plan

Finance - Pharmaceutical company completes private placement to accredited investors

Finance - Pharmaceutical company reports 3Q results, highlighted by launch of lead product

Finance - Pharmaceutical company reports 70% increase in third quarter revenues

Finance - Pharmaceutical company reports improved results for fiscal second quarter 2005

Finance - Pharmaceutical company reports record 3Q revenues of $18.1M

Finance - Pharmaceutical company reports third quarter 2004 financial results

Finance - Pharmaceutical company reports third quarter revenue increase of 58%

Finance - Pharmaceutical distributor reports best-ever quarterly sales

Finance - Pharmaceutical firm raises $25.7M in series C financing

Finance - Pharmaceutical firm reports 10% grow in sales

Finance - Pharmaceutical firm reports 13% increase in product sales

Finance - Pharmaceutical firm reports earnings of $0.49 per share

Finance - Pharmaceutical firm reports earnings per share of $0.38

Finance - Pharmaceutical firm reports loss of $1.63 per share

Finance - Pharmaceutical firm reports quarterly loss of $6.2M

Finance - Powerlink maker reports positive third-quarter results

Finance - Product-based biopharmaceutical company reports first quarter 2005 financials

Finance - Provider of Western products to China reports 30% revenue increase

Finance - QUADRAMET maker reports increased revenues

Finance - Radiographic systems maker reports increased sales and revenues

Finance - Research products maker reports 7% increase in sales

Finance - Respiratory care product maker has profitable first quarter

Finance - Selective drug discovery company completes third round financing

Finance - Software systems, services provider announces 5.3% growth in year revenues

Finance - Specialty pharmaceutical company reports third quarter financial results

Finance - Stretta system maker reports increased year-to-year sales

Finance - Therapeutics developer announces third quarter 2004 financial results

Finance - Transdermal drug delivery pharmaceutical reports third quarter EPS of $0.11

Finance - Transdermal drug delivery pharmaceutical reports third quarter financial results

Finance - Transdermal drug delivery technology company reports Q3 financial results

Finance - Vaccine company adopts shareholder rights plan

Finance - Vaccine maker reports Q3 revenues of $69,000

Finance - eTag System maker reports loss of $0.11 per share

Finances - Bridge financing for phase 2 trial on blood substitute set, phase 3 funds sought

Fitness - Study points to relationships between TV viewing, snacking and weight gain

Fitness & Wellness - Boutique pharmacy, Saks Department Store Group form business relationship

Fitness & Wellness - Bowflex recalls nearly 800,000 fitness machines

Fitness & Wellness - Nutrition products company finalizes agreement with Wellness Watchers Systems

Fitness & Wellness - Physical therapists offer tips to prevent holiday aches and pains

Fitness & Wellness - Tai Chi practitioners travel to China to compete and learn

Flexible Spending Accounts - Conexis launches employee-focused flexible benefits awareness program

Food Safety - Lateral flow strip for the detection of mycotoxins in grain introduced

Food Safety - Law requiring country of origin to be on food labels may be repealed

Food Safety - New test to detect hazardous toxins in grains, wine, nuts and coffee introduced

Forensics - Company helps police department use DNA to track burglary suspects

Fundraising - Travel agency launches program to benefit Milford Regional Medical Center

Gastric Cancer - IM and gastric adenocarcinoma may share the same genetic alterations

Gastric Cancer - Novel genes linked to 5-FU resistance identified in gastric tumor cells

Gastroenterology - Cytotoxic gene therapy is selective for human pancreatic cancer cells

Gastroenterology - Graft survival is lower in live donor liver transplant recipients

Gastroenterology - Specificity proteins are linked to the angiogenesis of pancreatic cancer

Gastroenterology - Spontaneous calcium signaling in bladder characterized

Gastroenterology - Spontaneous depolarization characterized in intestinal interstitial cells

Gastroenterology - Volume contrast ultrasound provides superior gallbladder imaging

Gastroesophageal Reflux Disease - New diagnostic approach to gastroesophageal reflux disease is a challenge

Gastroesophageal Reflux Disease - Two-year follow-up data released from Enteryx procedure clinical trial

Gender and Health - Study emphasizes importance of women in cardiac research

Gene Delivery - Steroids and cholesterol enhance liposomal transfection of breast cancer cells

Gene Expression - Company introduces new platform for gene-expression studies

Gene Expression - RhoA inactivation potentiates axon regeneration

Gene Profiling - DNA microarray of human sequence data available for life science researchers

Gene Profiling - U.S. Patent Office reissues patent for in vivo optical imaging for whole animals

Gene Research - Mutations in TBX1 are not involved in the cardiac phenotype of del22q11 patients

Gene Silencing - Silenced heat shock protein 27 discourages prostate cancer progression

Gene Testing - Licensing deal announced for MODY gene testing in Europe

Gene Therapy - Antibody-drug conjugate collaboration expanded

Gene Transfer - PEGylated polymers in lipiodolized emulsions garner support as gene vectors

Gene Vectors - Cytotoxicity and immunostimulation complicate lipoplex-mediated gene delivery

Gene Vectors - DOPE conjugation augments the work of DHP-12 lipoplex-based transfection

Generic Drugs - Combating generics: Early action protects market share

Genetic Disorders - Patients reveal a novel form of interleukin-12/IL-23 receptor beta 1 deficiency

Genetics & Genomics - Collaborative thrombophilia-markers study complete

Genetics & Genomics - Increased IL-10 might control inflammatory responses induced by vessel damage

Genetics & Genomics - Primary care clinicians and geneticists will collaborate

Genetics & Genomics - United Nations approves first international standard for human genetic test

Genomics - Completion of Haloarcula marismortui genome sequencing announced

Genomics - Horizontal gene transfer necessitates codon usage compatibility

Genomics Research - Virginia Tech, research institute sign memorandum to conduct genomics research

Genomics and Genetics - Quantitative trait loci for steady-state platelet count identified in mice

Genomics and Genetics - TfR1 mRNA downregulated in placenta of hepcidin transgenic embryos

Geriatric Care - Univ. of North Dakota center gets more money to study American Indian health

Geriatrics - Advocates speak about nursing home care in Rhode Island

Geriatrics - Report recommends $34 million to reform Texas elder care program

Gestational Diabetes - Fungi isolated from pregnant diabetic women have lower phosphatase activity

Gestational Diabetes - No link found between gene polymorphism and GDM in a Taiwanese population

Glaucoma - Heavy computer use linked with glaucoma in short-sighted people

Glioma - Selective targeting of VR1 by AEA: A promising area for research

Grants - Aetna, chief executive give $3.5 million to UConn for health programs

Grants - Louisiana State University dental school gets $10.7M for oral health research

Gulf War Syndrome - British unofficial inquiry says Gulf War syndrome is real

Gynecology - Hyaluronan synthase 1 expression associates with ovarian cancer progression

Gynecology - Sindbis viral vectors detect and suppress advanced ovarian cancer xenografts

HIPPA - Company announces preparedness for 2005 HIPAA security deadline

HIV Diagnostics - Company to begin shipping HIV-1 incidence test

HIV Therapy - Interim results reported from tipranavir RESIST-1 phase III study

HIV Treatment - Monoclonal antibody among HIV therapies discussed at human virology meeting

HIV/AIDS Behavior - Men and women equally distressed by sexual infidelity within the context of AIDS

HIV/AIDS Care - Family home AIDS care in rural sub-Saharan Africa is a minimal burden

HIV/AIDS Care - Level of HIV/AIDS patient care better if health facility funded by CARE Act

HIV/AIDS Cost - Household costs attributable to AIDS in Chad are devastating

HIV/AIDS Drug Adherence - HAART adherence shifts during HIV infection course for women caring for children

HIV/AIDS Economics - Expenditure more sensitive indicator of economic impact of HIV/AIDS than income

HIV/AIDS Epidemiology - Most recent common ancestor of HIV subtype C appeared in mid to late 1960s

HIV/AIDS Healthcare - HIV/AIDS patients in Malawi seek hospital healthcare as a last resort

HIV/AIDS Infection - HIV-1 DNA burden stable in monocytes and CD4 cells after ART resumption

HIV/AIDS Prevention - Gay sex workers play important role as sex educators on the Internet

HIV/AIDS Prevention - Russian government lacks will to combat spread of HIV/AIDS, experts say

HIV/AIDS Prevention - STD/HIV prevention website navigation tools not helpful enough for teenagers

HIV/AIDS Psychology - Internet is a viable recruitment tool for reaching HIV at-risk individuals

HIV/AIDS Research - Complement mediates HIV binding to erythrocytes

HIV/AIDS Research - Distinct mechanisms of HIV-1 Nef action in different populations of target cells

HIV/AIDS Research - Entry/transcription key determinants of CD4 T-cell permissiveness to HIV-1

HIV/AIDS Research - Fluorescent-labeled HIV-1 developed to investigate interaction with live cells

HIV/AIDS Research - Novel method targeting HIV-1-Ag-SCs identifies latently HIV-1-infected CD4 cells

HIV/AIDS Research - Prostratin antagonizes HIV latency by NF-kappa B activation

HIV/AIDS Research - Prostratin inhibits infection/reactivates latent HIV in PBLs/lymphoid tissue

HIV/AIDS Research - Raft-promotion of virion-associated cholesterol determines HIV-1 infectivity

HIV/AIDS Research - Riboswitch regulates RNA dimerization and packaging in HIV-1 virions

HIV/AIDS Research - Vpr nuclear localization crucial for efficient HIV-1 replication in CD4 cells

HIV/AIDS Risk - Online choice for sex-seeking among gay males varies with education level

HIV/AIDS Risk - Risky sex behavior among men associated with alcohol/drug use and other factors

HIV/AIDS Risk - Synchronous online interviews inherently unsuitable for exploring HIV risk

HIV/AIDS Screening - Diagnostics-focused biotech company receives U.S. FDA CLIA waiver for HIV test

HIV/AIDS Symptoms - Measuring validity of self-reported symptoms among people with HIV

HIV/AIDS Treatment - Antiretroviral use differs by sociodemographic differences

HIV/AIDS Treatment - Canadian HIV partnership lends financial support to phase 2 clinical drug trials

HIV/AIDS Treatment - Clinical study results build case for expanded use of FUZEON

HIV/AIDS Treatment - Data involving Combivir presented at recent meeting

HIV/AIDS Treatment - HIV CCR5 antagonist GW-873140 shows potent activity against primary isolates

HIV/AIDS Treatment - Novel HIV-1 mutation associated with resistance to nevirapine

HIV/AIDS Treatment - Racivir phase II HIV study initiated

HIV/AIDS Vaccine - Role of gastrointestinal T cells in HIV pathogenesis reviewed

HIV/AIDS Wasting - Custom-built facial implants helpful for patients with facial wasting syndrome

HIV/AIDS-Related Dementia - Discreet species of gp41 high-MW aggregates present in HIV-related dementia

Head and Neck Cancer - Advexin with chemotherapy promotes head and neck cancer cell death in studies

Health Education - Univ. of Tennessee opposing East Tennessee's bid to start pharmacy school

Health Outcomes - Promoting the health of the young will improve the health of people of all ages

Healthcare & Politics - Bush wants malpractice verdict limits, greater consumer role in healthcare

Healthcare & Politics - New institute looks at healthcare in the second Bush administration

Healthcare & Politics - Scottish Health and Safety Commission calls for 50 additional inspectors

Healthcare & Politics - U.S. Congress recognizes National Nurse Practitioner Week

Healthcare Access - Canyonville, Oregon, health clinic closing January 1

Healthcare Costs - GHI introduces new health insurance options for employer groups

Healthcare Costs - Study proposes aid for catastrophic care costs

Healthcare Coverage - Alabama Legislature approves governor's health insurance plan

Healthcare Coverage - Biotech company comments on CMS Remodulin reimbursement change

Healthcare Coverage - Gaps in pharmaceutical research and innovation can be closed, says WHO report

Healthcare Coverage - Harvard Pilgrim/Guardian to offer side-by-side health and dental coverage

Healthcare Coverage - Healthcare corporation subsidiary applies for HMO license in state of Georgia

Healthcare Coverage - Huge employer drops group health coverage

Healthcare Coverage - Humana Inc. launches SmartExpress for small business owners

Healthcare Coverage - Humana Military Healthcare Services completes TRICARE South Region transition

Healthcare Coverage - Legislative board considering request to lift premiums for some in Oregon plan

Healthcare Coverage - Medicaid doctors may have to 'clinically justify' some drugs

Healthcare Coverage - North Carolina awards state pharmacy benefit program in 4-year agreement

Healthcare Coverage - Official says 'modernizing' Medicaid could improve care, lower costs

Healthcare Coverage - Program offers lower-income adults and children access to medications

Healthcare Coverage - Senate chief says cut number of Massachusetts's uninsured in half by 2006

Healthcare Coverage - Senior private duty home care group offers client outcome benchmarking

Healthcare Coverage - Study finds almost 90% of Americans expect serious health condition in 5 years

Healthcare Coverage - TennCare advocates back off court wins in effort to save program

Healthcare Coverage - U.S. veterans give VA top healthcare rating for 5 years in a row

Healthcare Coverage - Workshop to be held to standardize pay-for-performance principles

Healthcare Delivery - Healthcare service enables patient to pick time, place for no-wait appointment

Healthcare Expense - New Mexico retiree group seeks budget help from lawmakers

Healthcare Facilities - URAC renews accreditation of disease management programs care services company

Healthcare Financing - Can poor countries help rich countries contain drug costs?

Healthcare Financing - Diabetes among older adults imposed an estimated $133.5 billion cost in 1990s

Healthcare Fraud - Urologist pleads guilty to healthcare fraud

Healthcare Management - Company introduces new anesthesia workstation

Healthcare Management - Medical staffing firm announces new Web site and results of a nurse satisfaction survey

Healthcare Management - Over-the-counter medications can provide financial benefits

Healthcare Management - Pennsylvania diabetes report reinforces need for healthy lifestyles

Healthcare Reform - Survey indicates voters have new vision of healthcare reform

Hearing Disorder - Virus-mediated gene transfer is a candidate for treating hearing loss

Heart Disease - Etiology must determine surgical treatment for sudden cardiac death in children

Heart Disease - Hedgehog pathway restores cardiac function in preclinical models of heart attack

Heart Disease - U.S. FDA allows qualified health claim regarding risk of coronary heart disease

Heart Disease - Ultrasound exam helps identify patients at risk for cardiovascular disease

Heart Disease - VHI offers hospital mortality information on cardiac care

Heart Disease Risk - As obesity increases in diabetics, so does risk of cardiovascular disease

Heart Disease Risk Factor - Angiotensin-induced vasoconstriction is increased in upper body obesity

Heart Failure - Both ischemic and dilated myocardium showed increased IL-18 receptor levels

Heart Failure - Data from heart-failure drug-discovery program presented at AHA meeting

Heart Failure - Heart failure clinics with nurse intervention should be an integral part of care

Heart Failure - Patient celebrates 1-year anniversary supported by Thoratec HeartMate II

Heart Failure - Positive trial results reported on cardiac support device

Heart Mitochondria - Review covers particular aspects of the emerging field of mitochondrial medicine

Heart Monitoring - Imaging company awarded U.S. National Institutes of Health grant

Heart Pumps - First DeBakey VAD implanted for destination therapy

Helathcare Coverage - Health plan to manage radiology services for Health Net

Helicobacter Vaccine - Mechanisms of vaccine-induced protection against H. pylori reviewed

Hematology - Effects of turbulent stresses on mechanical hemolysis determined

Hematology - Late thrombosis reported in drug-eluting coronary stent recipients

Hematopoiesis - Nitric oxide is a regulator of hematopoietic stem cell activity

Hemodialysis - Improved water quality reduces inflammation

Hemorrhagic Fever - Signal peptide of arenavirus glycoprotein forms mature G1-G2 complex subunit

Heparin - Results support a 'double bridge' mechanism for HCII inhibition of thrombin

Hepatic Cancer - Phase I data evaluating BAY 43-9006 plus conventional chemo released

Hepatitis B - Positive results reported from phase I/II trial of ANA380 (LB80380)

Hepatitis C - Data on HCV protease inhibitor drug candidates presented at AASLD meeting

Hepatitis C Virus - Payment received from GlaxoSmithKline relating to HEV vaccine

Hepatitis C Virus - Pharmaceuticals advances to phase 1b trial for drug treatment of hepatitis C

Hepatocellular Carcinoma - Improved dose calculation method devised for yttrium-90 microspheres

Hepatology - NO-mediated S-nitrosylation inhibits flavin-containing monooxygenase

Hepatology - The clinical viability of liver gene therapy is still unresolved

Herpesvirus - Early expression of HSV-1 ICP27 transcript not critical for replication

Hip Replacement - Corrosion of cemented titanium femoral stems characterized

Hip Replacement - Risk factors for perioperative blood transfusion identified

Hip System - Fully automated lab-on-a-chip system launched for research

Hormone Therapy - Oxidative metabolism of estrogen modulates ERT/HRT response in older women

Human Papillomavirus - Factors associated with HPV-16 seropersistence in Costa Rican women identified

Human Papillomavirus - Inflammatory responses in cervical neoplasia suppressed in HIV-positive women

Human Papillomavirus - Methods of identifying new antigenic epitopes of HPV 16 developed

Human Papillomavirus - Prevalence of HPV infection differs for men and women

Human Papillomavirus Vaccine - Dendritic cell-based vaccines effective against HPV-associated tumors

Human T Lymphotropic Virus - Novel SNP in human perforin gene associated with outcome of HTLV-1 infection

Hypercholesterolemia - A chocolate snack can lower cholesterol levels

Hyperplasia - Study explored methylprednisolone administration to suppress hyperplasia

Hypertension - Abdominal aorta and kidney may be targets for antihypertensive dipeptide

Hypertension - Poll shows hypertensives are hard on their hearts during winter holidays

Hypertension - Regulatory review process for bosentan in final stage in Japan

Hypertension - Study mimicked a high salt diet in mice

Hypertension Therapy - Conjugated linoleic acid prevents hypertension in hypertensive rats

Hysteroscopic Myomectomy - Immersion Medical introduces educational Hysteroscopic Myomectomy CD

Imaging - Computer reads heart condition from X-ray images

Imaging - Local fuzzy fractal dimension provides information for segmenting ECGs

Imaging Technology - Digital slot-scan mammography may reduce X-ray dose, improve image quality

Immunization - Accelerated hepatitis B vaccine schedules protect prisoners better

Immunization - Continuous antigenic stimulation is new immunization strategy

Immunology - B subunit of E. coli enterotoxin induces apoptosis in CD8+ T cells

Immunology - B1b lymphocytes confer T cell-independent long-lasting immunity

Immunology - Chemokine receptor-mediated delivery induces protective immunity in vivo

Immunology - Dendritic cells require bcl-xL expression for in vivo survival

Immunology - Functional microtubules needed for APC antigen processing

Immunology - Heat shock protein suicide gene-based tumor vaccine provokes antitumor activity

Immunology - Intestinal epithelial antigen induces mucosal CD8 T cell tolerance

Immunology - KIRs modulate T cell activation through DAP12-dependent/independent mechanisms

Immunology - LFA-1 on CD4+ T cells required for optimal antigen-dependent activation

Immunology - MDS-derived T-cell line is cytotoxic to CD34+ stem cells

Immunology - Nondepleting CD4 antibody induces immunological tolerance in baboons

Immunology - Oligosaccharides may influence lymphocyte maturation in breastfed newborns

Immunology - Role of IgG2b in mucosal tolerance induction investigated

Immunology - SNAP-25 present in rat mast cells

Immunology - TLRs differentially expressed in distinct regions of female reproductive tract

Immunosuppressive Therapy - Drug selection has little impact on hepatitis C severity after liver grafts

Immunotherapy - Dendritic-like cells derived from t(9;22) ALL blasts may be useful immunotherapy

Implantable Cardioverter Defibrillator - ICD therapy poses unique issues for women

Infection - Methicillin resistance did not affect mortality of patients with VAP

Inflammation - Gene-modified macrophages recognize apoptotic cells

Influenza - NIAID launches influenza genome sequencing project

Influenza - Neugene antisense drugs reported to suppress influenza A virus

Influenza - Take steps to minimize risk if getting the flu even without shot, expert says

Influenza - WHO says flu vaccine coming within year

Influenza Outbreak - Flu season starts in Oregon

Influenza Vaccine - Alabama nursing homes still waiting for flu shots

Influenza Vaccine - Chiron asks British regulators to inspect flu vaccine facility

Influenza Vaccine - HHS head Thompson announces contract to support egg supply for flu vaccines

Influenza Vaccine - Hawaii opens flu shot clinics for chronically ill

Influenza Vaccine - Ineffective vaccine given to about 300 in Arkansas, health official says

Influenza Vaccine - Senator says money for new flu vaccine research probably on the

Influenza Vaccine - Utah lifting flu shot restrictions

Influenza Vaccine - Vermont to hold 17 flu shot clinics

Information Technology - Brotman Medical Center connects cardiac physicians to TCS Symphony

Information Technology - Computer systems, software developers launch DNA sequencing, management system

Information Technology - Drug Web sites foster doctor and patient loyalty

Information Technology - Educational healthcare web site wins medical marketing industry award

Information Technology - Epocrates Essentials clinical reference suite available for pocket PC devices

Information Technology - HIPPA-compliant AdvancedMD v4.2 software released

Information Technology - Healthcare information provider announces availability of 2004 HPD

Information Technology - High-tech company joins medical experts to commercialize technology

Information Technology - Indiana heart center adopts integrated cardiology software system

Information Technology - Information systems provider partners with healthcare software developer

Information Technology - Missouri healthcare group to use computer information predictive modeling system

Information Technology - National health plan showcases online health programs during open enrollment

Information Technology - Next of Kin Project picks wireless phone company to propagate Next of Kin law

Information Technology - Physician benchmarking module launched

Information Technology - Solucient delivers data using software from healthcare information company

Information Technology - Support of cordless hand scanner for Windows XP Notebook and Tablet released

Information Technology - UCLA Medical Group to deliver healthcare online to patients in reimbursed plans

Injury Prevention - Hands-free cell phones dangerously distract drivers' attention

Insulin Resistance - IKK-beta inhibitor ameliorates obesity-linked insulin resistance

Insulin Resistance - Insulin receptor serine phosphorylation linked to insulin resistance

Insulin Resistance - Phosphorylation of insulin receptor increased in obese rats

Ischemia - An NO-dependent mechanism mediates sex difference in [Na+]i regulation

Ischemia - Hemodilution worsened neurological function, increased cerebral infarct volume

Ischemia - Positive effects of isoflurane during ischemia depend upon PKC activation

Ischemia/Reperfusion - PKC contributes to the cardioprotection afforded by intermittent hypoxia

Ischemic Preconditioning - Study investigates effect of beta-adrenoreceptor antagonists on preconditioning

Isocapnic Hyperpnoea - Post-hyperventilation hyperpnoea, when present, is a strong, lasting phenomenon

Isocapnic Hypoxia - Cerebral vasculature fails to react to hypoxia during sleep

Joint Replacement - Long-term survival of silastic metacarpophalangeal replacement determined

Kaposi Sarcoma-Associated Herpesvirus - Herpesvirus saimiri ORF73 modulates tumor suppressor proteins p53 and pRb

Kaposi Sarcoma-Associated Herpesvirus - KSHV LANA up-regulates hTERT promoter transcription through Sp1 interaction

Kidney Disease - Angiotensin II type 1A receptor deletion does not sway renal disease

Kidney Disease - BMP-7 reverses vascular calcification in a preclinical model of chronic kidney disease

Kidney Disease - Company reports beneficial effects of seliciclib in models of kidney disease

Kidney Disease - E.U. approves treatment for chronic kidney disease complication

Kidney Disease - IDEXX Laboratories announces Urine P:C Ratio for VetTest Chemistry Analyzer

Kidney Transplantation - Anti-MHC-class-II antibody delays rejection, but triggers CMV activation

Kidney Transplantation - Calcineurin inhibitor-free immunosuppression improves graft outcome

Knee Replacement - High-dose antibiotic-loaded cement spacers safe

Knee Replacement - Patient preferences in knee prostheses determined

Lab Tools - Biotech company introduces TrialVial for screening experiments

Laboratory Methods - Study investigated methods of euthanasia for mouse fetuses and neonates

Laser Treatment - Company announces Medicare/Medicaid reimbursement for EVLT

Lead Poisoning - Recommendations of a task force on lead poisoning

Left Ventricular Hypertrophy - Enlarged heart can lead to heart attacks even after blood pressure goes down

Legal Issues - Ablation and vacuum-technology company resolves class-action litigation

Legal Issues - Biosurgical-device company reports settlement of cases

Legal Issues - Former National Century executive admits conspiracy

Legal Issues - Judge temporarily blocks Florida's new amendment on bad doctors

Legal Issues - Pharmaceutical's former employees challenge benefits move in division spin-off

Legal Issues - Wyoming leader calls for law against bodily fluid attacks

Leishmaniasis Vaccine -  Leishmania major exogenous antigens protects against infection

Leishmaniasis Vaccine - Central memory T cells mediate long-term immunity to Leishmania major

Leishmaniasis Vaccine - T cells mediate immunity to Leishmania major in absence of parasites

Lentivirus - Cell-free systems compare capsid assembly of genetically diverse lentiviruses

Lentivirus - Lentivirus clone SIVmac239 does not complete capsid assembly in cell-free system

Lentivirus - Self-inactivating lentiviral vectors resist proviral methylation

Leptin Studies - Hyperleptinemia prevents lipotoxic cardiomyopathy in transgenic mice

Leptin Studies - Leptin circadian phase difference in android and gynoid obesity found

Leptin Studies - Leptin, thyroid hormones determined in obese women after energy deficit

Leptin Study - Leptin inhibits norepinephrine efflux from the hypothalamus in vitro

Leukemia Vaccine - Leukemic cells have high B7-H1 and B7.1 expression and resist lysis

Lipid Disorders - FDA grants approval for new formulation of TriCor

Lipid Studies - Lipid level relation to heart disease in type 2 diabetes examined

Lipogenesis - Cholesterol-synthesizing machinery is well developed in premature infants

Lipoprotein - ApoE increases the rate of phospholipid and triacylglycerol hydrolysis in rHDL

Listeria Vaccine -  Listeria monocytogenes aro mutants show promise as vaccine candidates

Liver Disease - Company presents new immunomodulatory research at liver disease conference

Liver Failure - Bioartificial liver preclinical data show it increased survival in animals

Liver Pathology - Histopathologic findings of acute rejection after liver grafts can be wrong

Liver Transplant - Positive HIV status is not a strict contraindication for liver transplantation

Liver Transplantation - Sirolimus is suited for patients given liver transplants due to liver cancer

Low Birth Weight - Affluent countries should embrace "kangaroo" care

Lumbar Spinal Stenosis - Spinal disorders-focused company receives U.S. FDA notice on for LSS device

Lung Cancer - Cancer vaccine helped patients in phase IIb trial survive 4.4 months longer

Lung Cancer - Genes overexpressed in NSCLC identified

Lung Cancer - New protein identified in development of lung cancer

Lyme Disease -  Borrelia burgdorferi changes antigens based on host immune response

Lyme Disease - Receptor identified in tick guts

Lymphoma - NCI scientists create model that predicts follicular lymphoma survival

Lymphoma - Prostatic acid phosphatase is marker for intravascular large B-cell lymphoma

MMR Vaccine - Differential immune responses to MMR vaccine in Israeli children documented

Macular Degeneration - Study shows stem cells can preserve vision

Magnet Resonance Imaging - Medical device company ships 100th 1.5 Tesla MRI system

Malaria - Cytokine levels in Malian children with severe malaria determined

Malaria - Fine specificity of merozoite antibodies linked to malaria resistance

Malaria Vaccine -  Plasmodium yoelii proteins enhance protection against malaria

Malaria Vaccine - Anatomy of Plasmodium falciparum MSP-1 epitope mapped

Malaria Vaccine - Antigenic drift in Plasmodium vivax protein confers antibody resistance

Malaria Vaccine - Immunogenicities of Plasmodium vivax protein fragments compared

Malaria Vaccine - Merozoite protein protects against lethal malaria parasite challenge

Malignancies - HGS-TR2J, TRAIL-R2 preclinical study results presented at 29th Congress of ESMO

Mammography - Poland's leading cancer institute selects CT laser mammography system

Market Analysis - Aggressive marketing, manageable side effects to aid migraine drug market

Market Analysis - Overall healthiness in U.S. slowing dramatically

Market Analysis - Report details progress in the leukemia therapeutics market

Maternal Mortality - Skilled attendants vital to saving lives of mothers and newborns

Measles Vaccine - Measles vaccination rate in developed world

Medical Devices - Artificial vasculature device may provide better coronary perfusion than VADs

Medical Devices - Biology instruments maker places molecular analyzer at Sinai School of Medicine

Medical Devices - Medical device company announces results of hemodiafilter study

Medical Devices - New products help detect heart problems sooner and avoid invasive procedures

Medical Devices - Syringe maker announces sales, distribution partnership with Chinese producer

Medical Education - South Florida cancer center seeks students for summer intern program

Medical Equipment - Medical device company signs 3-year catheter contract with Premier

Medical Facilities - Michigan health system dedicates Fred and Lena Meijer Heart Center

Medical Fraud - Agents search medical business seeking evidence of fraud

Medical Malpractice - Number of malpractice payments declines, size of payments soars

Medical Malpractice - Rising malpractice premiums affecting entire Maryland economy, analysis finds

Medical Profession - Survey suggests majority of female surgeons satisfied in their profession

Medical Records - New program provides quicker access to medical information

Medical Research - Quality of science more important to physicians than sponsorship, study shows

Medicare Coverage - Company focused on morbidly obese comments on Medicare coverage determinations

Medicare/Medicaid Coverage - Physical therapy company helps physicians deal with new Medicare PT ruling

Melanoma - Data updates from phase 2 trial for metastatic melanoma drug presented

Melanoma Vaccine - Quiescent phenotype of tumor-specific CD8+ T cells following immunization

Meningitis Epidemiology -  Haemophilus influenzae incidence in South Korean children reported

Meningitis Vaccine - Protection against N. meningitidis found without bactericidal activity

Meningococcal Vaccine - Distribution of protein variants among meningococci aids vaccine design

Meningococcal Vaccine - Intranasal immunization with liposomes plus meningococcal proteins studied

Mental Health - Agency finds 48% increase in involuntary commitments since law changed

Mental Health - Long-term transdermal nicotine treatment can improve mood and sleep

Mental Health - New Jersey Governor begins tenure with push for mental health protections

Mercury - Inorganic mercury accumulated in the brains of offspring

Mergers & Acquisitions - Acquire VISX acquisition to create comprehensive ophthalmic medical device company

Mergers & Acquisitions - Agreement to entered for purchase of infant formula manufacturing facility

Mergers & Acquisitions - Biotechnology company amends merger agreement with HIV-focused pharm firm

Mergers & Acquisitions - Biotechnology holding company signs agreement to acquire Portage Biomed

Mergers & Acquisitions - Broadlane acquires National Oncology Alliance

Mergers & Acquisitions - Cell therapy developer completes acquisition of Opexa Pharmaceuticals

Mergers & Acquisitions - Company amends merger agreement with V.I. Technologies

Mergers & Acquisitions - Company sells medical product businesses and brands to Aspen Surgical Products

Mergers & Acquisitions - Healthcare corporation agrees to sell California hospital to CHA Medical Group

Mergers & Acquisitions - MTA provider acquires NoInk Communications

Mergers & Acquisitions - Medical transcription company acquired by equity firms in recapitalization move

Mergers & Acquisitions - Surgery center owner and operator acquires two centers in Alabama

Mergers & Acquisitions - Suturing device company updates proposed merger with Millenium, evaluates option

Mergers & Acquistions - Plant, soil product provider acquires VAMTech Inc.

Mergers and Acquisitions - DNA Research Innovations, Ltd., acquisition announced

Metabolic Syndrome - Hormone therapy improves risk factors in postmenopausal women

Metabolic Syndrome - Lipoprotein transport in metabolic syndrome investigated

Metabolism - Physical activity, gender affect lipid metabolism

Metabolism - To weigh less, eat more

Metastatic Lung Cancer - Positive results reported from INGN 401 studies in metastatic lung cancer

Military Healthcare - U.S. VA officials say mental health of soldiers a top priority

Mitral Valve - Percutaneous mitral valve repair shows favorable preliminary results

Molecular Pharmacology - Inhibitors may have therapeutic potential for ischemic disease, arrhythmias

Morbid Obesity - Action of cisatracurium in morbidly obese women investigated

Multiple Myeloma - Anti-alpha4 integrin antibody inhibits tumor cell growth and osteolysis

Multiple Sclerosis - Antegren 1-year data from phase III AFFIRM study showed compelling results

Multiple Sclerosis - Country music star attends multiple sclerosis leadership conference

Multiple Sclerosis - Rebif redesigned for easier administration for multiple sclerosis patients

Muscular Dystrophy - Research focuses on early mechanisms of neuromuscular disease

Mutagenesis - A new transfection protocol improves the study of hepatitis B virus mutants

Myocardial Infarction - Consider bypass in conjunction with repair of posinfarct mechanical complication

Myocardial Infarction - Method developed to replicate stem cells from the heart

Myocardial Infarction - Unexpectedly high levels of depression seen in young women after heart attacks

Myocardial Revascularization - Choice of operative technique is not associated with reduced renal morbidity

Nanotechnology - Nanoparticles could aid medical diagnosis, therapy in fraction of previous time

Nanotechnology - Nanotechnology conference explores innovation and opportunity

Natural Products - Anticancer effects are increased with increased levels of alliin in garlic

Neonatology - Premature infants may continue to need replacement substance to ease breathing

Nephrology - Endothelin A receptor antagonism and ACE inhibition are a promising combination

Nephropathy - U.S FDA grants orphan drug designation for CR002 in IgA nephropathy indication

Neural Stem Cell Research - Akt-1 expression level regulates CNS precursors

Neural Stem Cell Research - Thyroid hormone participates in the regulation of neural stem cells

Neural Stem Cell Research - p107 regulates neural precursor cells in the brain

Neurodegeneration - Neuroprotection and Parkinson disease programs presented at meeting

Neurodegeneration - TWEAK induces neuronal cell death and is involved in neurodegeneration

Neurodegenerative Dementia - Results do not support the view that ApoE is a biochemical marker for dementia

Neurodegenerative Disease - Transient cerebral ischemia induces site-specific tau hyperphosphorylation

Neuroendocrinology - ER-alpha in cholinergic neurons of aged female mice respond to estrogen changes

Neuroendocrinology - Ovariectomy-associated memory deficits in mice improve by estropausal age

Neurogenesis - Aging results in deficits in fine olfactory discrimination

Neurology - Beckley doctor believes brain can control robots

Neurology - Companies announce agreement for technology used in clinical trials of stroke treatment

Neurology - Company present efficacy data on retinitis pigmentosa treatment

Neurology - Pharmaceutical company receives license for new stroke treatment

Neuropathy - Immunization protocols for motor axonal neuropathy rabbit model compared

Neuroscience - CXCR4 involved in migration of neural precursor cells

Neuroscience - Improved serotonin transporter imaging agent developed

Neuroscience - Integrin-associated proteins are important for dendritic outgrowth

Neuroscience - Laser probe simultaneously records multiple thalamic field potentials

Neuroscience - Neurotensin inhibits dopamine-dependent locomotion and stereotypy

Neuroscience - Novel syntaxin-1-binding protein identified

Neuroscience - Real-time synchrony map of visual cortex developed

Neuroscience - Rodent brains respond to acute oxygen imbalances with capillary formation

Neuroscience - Role of PTP-BL tyrosine phosphatase elucidated

Neuroscience - S-100b protein useful as biomarker of ischemic brain injury

Newborn Screening - California's selects mass spectrometry system for expanded newborn screening

Nicotine Addiction - Grant to study why teens smoke

Nicotine Addiction - Smoking is in the genes

Nitrite Inhalant - Macrophage IL-1 beta production inhibits caspase-1 after nitrite inhalation

Non-Hodgkin Lymphoma - Marqibo NDS filed with TPD of Health Canada for non-Hodgkin lymphoma

Non-Hodgkin Lymphoma - Yttrium 90-labeled ibritumomab effective for NHL patients

Nutrition - Active people can make mistakes in their diet

Nutrition - Cancer experts comment on new diet-cancer study

Nutrition - Concord grape juice increases HDL, lowers inflammatory markers

Nutrition - Dietary supplements manufacturer endorses dietary supplement act

Nutrition - Malnutrition in early years leads to low IQ and later antisocial behavior

Nutrition - New research studies confirm safety of chromium picolinate

Nutrition - Portion control, not sweetness, is issue, says food think tank

Nutrition - Vegetable lovers should be viewed as different from fruit aficionados

Obesity - Low-fat beats low-carb for keeping pounds off, study suggests

Obesity - New obesity survey reveals vastly differing viewpoints by nationality

Obesity - Society for Study of Obesity, diabetes association fight twin epidemics

Obesity - Study links sleep deprivation, greater weight

Obesity - U.S. fast food chain introduces new mega-calorie Monster Thickburger

Obesity Genomics and Genetics - Regulation of nitric oxide system in human adipose tissue reviewed

Obesity Risk Factor - Morbillivirus used to investigate viral-induced obesity

Obesity Surgery - Gastric bypass works for GERD and obesity in patients with prior surgery

Obesity Therapy - Activity of potential anti-obesity compounds optimized

Obstetrics - Certain intrauterine infections may cause trophoblast apoptosis through TLRs

Obstetrics - Folic acid supplements during pregnancy reduce whole blood coagulability

Obstetrics - Leptin signals probably not a key factor in preeclampsia pathogenesis

Obstetrics - Mechanisms of hypoxia-induced fetal growth restriction studied

Obstetrics - Night work linked to increased risk of late pregnancy loss

Obstetrics - Premies' infections increase risk for mental, physical problems

Obstetrics - Survey results prompt improved obstetric care in Mali

Obstetrics - U.S. FDA adds new warnings to mifepristone labeling

Obstetrics - U.S. sees steep rise in elective cesarean deliveries

Occupational Health - Occupational health and gorilla conservation in Rwanda

Occupational Health - Stress at work contributes to musculoskeletal disorders

Oncogenesis - Aged mice develop protective antitumor immune responses with costimulation

Oncogenesis - Hepatitis C virus infection elevates one's risk for non-Hodgkin lymphoma

Oncogenesis - Nuclear factor-kappa B rules the malignant phenotype of squamous cell carcinoma

Oncology - $10 million grant to evaluate lifestyle changes on breast cancer patients

Oncology - Angiopoietin-2 is a prognostic marker for non-small cell lung cancer

Oncology - Bcl-xL knockdown strengthens TRAIL-induced death in prostate cancer cells

Oncology - Bevacizumab reduces tumor progression in patients with metastatic renal cancer

Oncology - Combined chemotherapy and immunotherapy generates tumor rejection

Oncology - Ets-1 transcription factors are involved in human breast cancer metastasis

Oncology - Occult neoplastic cells predict recurrence in node-negative breast cancer

Oncology - Pharmaceutical company announces Phase I clinical trial for myeloma treatment

Oncology - Plasma from pregnant rats has antitumoral activity

Oncology - STAG1 is a chief intermediary of the p53-dependent pro-apoptotic pathway

Oncology - The Shc protein is involved in a continuum leading to liver cancer

Oncology - Tumor MGC4175 expression linked to taxol and doxorubicin resistance

Oncology - Xcytrin data prsented at Chemotherapy Foundation Symposium XXII

Oncology Research - Survivor, patient advocacy group started to support cancer advancements

Ophthalmic Laser - Company launches new photocoagulator at AAO meeting

Ophthalmic Surgery - Clinical guidelines released for new Intralase FS laser therapeutic applications

Ophthalmic Surgery - Orbital myiasis in patient with a exposed hydroxyapatite implant described

Ophthalmology - Lens company reports third quarter results

Ophthalmology - Manufacturing agreement announced for ophthalmic digital imaging systems

Ophthalmology - Researchers identify genetic cause of rare eye disease in Utah family

Ophthalmology - Scientists develop "electronic eye" for the blind

Opioid Receptor - Study examines effects of kappa-opioid receptor on neonatal ventricular myocytes

Opthalmic Surgery - Longer discontinuance of rigid contact lens use before LASIK surgery recommended

Oral Health - Proinflammatory cytokines in dental fibroblasts invite tissue destruction

Oral Health - The market for betel quid is increasing despite risk to oral health

Orthopedics - Data shows benefits of quadriceps-sparing knee surgery

Orthopedics - Effort examines androgen's role in bone loss

Orthopedics - Oral contraceptives improve knee-joint stability

Osteoporosis - Beneficial effects of alendronate or exercise lost when therapy is stopped

Osteoporosis - Body composition changes with age have gender-specific impacts on BMD

Osteoporosis - Daily and intermittent oral ibandronate normalizes bone turnover

Osteoporosis - Glabridin acts similarly to estradiol-17beta and may modulate bone health

Osteoporosis - Hyperhomocysteinemia due to low folate associated with low BMD in Iranian study

Osteoporosis - IL-6 promoter polymorphism associated with bone quality in postmenopausal women

Osteoporosis - Low calcium intake, inactivity, older age are risk factors in Thai women

Osteoporosis - Moderate-to-vigorous exercise needed to improve skeletal status of young people

Osteoporosis - NPY signal gene polymorphism may benefit postmenopausal femoral neck BMD

Osteoporosis - Postmenopausal ER loss diminishes estrogen's anti-nociceptive action

Osteoporosis - Study: Elderly women with distal radial fracture have low hip, lumbar spine BMD

Osteosarcoma - Cytogenetic profile of tumor cells clarified

Otology - Smoking not linked to hearing loss

Ovarian Cancer - 42-bp deletion within ERCC1 5' UTR can affect therapeutic cisplatin response

Ovarian Cancer - Focal adhesion kinase may be important therapeutic target

Ovarian Cancer - Gene expression profiling aids in ovarian cancer prognosis

Ovarian Cancer - Hypermethylation is a common, relatively early event in ovarian tumorigenesis

Ovarian Cancer - Loss of beta-catenin associated with poor survival

Ovarian Cancer - Study: Urinary incontinence, abdominal pain are key early warning signs

Ovarian Cancer - Trial compares docetaxel to paclitaxel for first-line treatment of cancer

Ovarian Cancer - p53 deficiency alone doesn't prompt ovarian epithelial tumorigenesis in mice

Ovarian cancer - SFRP1 gene is inactivated by promoter methylation in human ovarian cancers

Oxygen Uptake - Priming exercise does not influence time constant of VO2 response

Pacemakers - Strain Doppler imaging is useful to predict the efficacy of biventricular pacing

Pain Medicine - Generic anti-inflammatory drug causes fewer gastrointestinal complications

Pain Medicine - Overdose in patient with intrathecal drug delivery system reported

Pain Medicine - Role of cholecystokinin in pain elucidated

Pain Medicine - Spinal cholinergic activity increases after aspirin treatment in rats

Pain Medicine - Survey: Doctors cautiously supportive of COX-2 drugs in wake of Vioxx withdrawal

Pain Medicine - Transdermal fentanyl compared to IV PCA morphine after gynecologic surgery

Pain Medicine - Transdermal fentanyl reduces pain and cortisol levels in non-cancer patients

Pain Relief - First Medicare coverage of ON-Q PainBuster announced

Paleontology - Dinosaurs sported armor similar to today's bullet-proof vests

Pancreatic Cancer - Photothermal assay detects nicotine-induced tumor cell apoptosis

Pancreatic Exocrine Insufficiency - Pharmaceutical company, Novozymes sign agreement to develop pancreatic enzymes

Pancreatic Islets - Cross-talk between kinases mediates survival of isolated human islets

Papillomatosis - HLA alleles regulate disease severity in recurrent respiratory papillomatosis

Parkinson Disease - Biosciences company enters license agreement with Almirall for Parkinson

Parkinson Disease - L-DOPA with CGS 21680 may open new therapeutic avenues for Parkinson disease

Parvovirus Therapy - Sequestration of receptor by NS2 mutations regulates parvovirus fitness

Patents - Anticancer drug receives Candian patent

Patents - Canada-based biotechnology company receives U.S. patent for vaccine production

Patents - Collagen Infusion Delivery System receives U.S. patent

Patents - Genospectra takes a commercial license to bead patents

Patents - SomatoKine granted European patent for treatment of diabetes

Patient Care - Hospitals turning to medical interpreters to avoid 'charades'

Patient Care - Remote-control robots help doctors save time, see more patients

Patient Confidentiality - Woman sues over display of medical file in breast cancer awareness

Patient Education - HOPE celebrates 6th anniversary of the diabetes education program in Hangzhou

Patient Safety - Survey helps hospitals measure and improve safety culture

Pediatric Cancer - U.S. NCI pediatric program established under contract to research hospital

Pediatric Oncology - Gene therapy promoters should be inspected for their effects in local tissues

Pediatrics - Breastfeeding best for preventing misaligned baby teeth

Pediatrics - California social services announces 'surrendered baby' awareness campaign

Pediatrics - Conference explored the evolution of academic general pediatrics

Pediatrics - Mother-infant relationship studied in cases of triplets

Pediatrics - Nation's largest study tracks children's health

Pediatrics - Pediatric nutrition company lists steps to keep families well during flu season

Pediatrics - Prosthetics forms strategic alliances in six states

Peptide Synthesis - German company selects CEM for medicinal chemistry research

Peptide Synthesis - Synthetic peptidyl ligands are used for isolating plasminogen activators

Percutaneous Coronary Intervention - Company reports first hospital sales of Angiox in Europe

Pericardium - Review describes the pericardium and dynamic interactions with the heart

Peripheral Arterial Disease - Phase 2 clinical data in peripheral arterial disease presented at AHA sessions

Personnel - Additions to staff ensure leadership in oncology clinical research

Personnel - Alabama mental health commissioner to retire February 1

Personnel - Alan Sheppard named head of generics business in Europe

Personnel - Allina Hospitals & Clinics board of directors names Edson W. Spencer, Jr.

Personnel - Backoff promoted to senior general manager by Florida hospice care group

Personnel - Biopharmaceutical company names new chief executive officer

Personnel - Biopharmaceutical company president to resign

Personnel - Biotech company reports organizational changes

Personnel - Biotech oral health company names new business development leader

Personnel - Bone tissue company appoints new board members

Personnel - COO Tom Mills leaves home healthcare provider, Frank Powers joins firm as VP

Personnel - Cardiology company adds employees with expansion of cell transplantation trials

Personnel - Centura Health names chief medical officer

Personnel - Christy Beaudin named Fellow for foundation's leadership program

Personnel - Cigna HealthCare appoints Frank Monahan as general manager

Personnel - Clinical research company announces new regulatory affairs leader

Personnel - CompONE names new chief executive and financial officers

Personnel - Coventry Health Care elects Dale B. Wolf to board of directors

Personnel - Craig A. Dionne named foundation's executive VP of research and therapeutics

Personnel - Dave Carlucci named CEO, David Thomas remains executive chairman of market group

Personnel - Denise Fletcher named CFO of DaVita

Personnel - Device maker announces senior management addition

Personnel - Diabetes device supplier expands executive management

Personnel - Diabetic Treatment Centers of America hires Dr. Sherman B. Johnson, MD

Personnel - E. Michael Prater resigns as director of drug-development company

Personnel - Flu vaccine maker names Jack Goldstein interim COO, Anne Hill VP of HR

Personnel - Former AT&T, IBM executive Earley named president, COO of health insurance group

Personnel - Former Colorado Univ. department chair asks court for his job back

Personnel - Former Tennessee mental health commissioner James Brown is dead

Personnel - Full service consultancy names president

Personnel - Haig takes over from father as chairman of the board

Personnel - Health alliance president David J. McIntyre named to USO Board of Governors

Personnel - Health care company announces executive management appointments

Personnel - Healthcare private equipty firm names Pratik Shah, PhD, new venture partner

Personnel - James Caggiano named VP sales and marketing; will focus on Provenge

Personnel - Lab technology company expands executive management team

Personnel - Life sciences firm expands board of directors

Personnel - Martin Kaplan, U.N. scientist and former head of Pugwash, dies at 89

Personnel - Medical device company confirms appointment of non-executive director

Personnel - Medical device company names new director and officer

Personnel - Medical device firm changes research, development department

Personnel - Neurotechnology company adds director and finance VP

Personnel - Oncology-focused company names Dr. Gloria Lee VP of clinical R&D

Personnel - Oncology-focused pharmaceutical names new heads of biologics, regulatory affairs

Personnel - Perry Habib named VP marketing at eye care company

Personnel - Petillo named president, Univ. of Medicine and Dentistry of New Jersey

Personnel - Pharmaceutical firm promotes Mary Kay Ladone to VP of investor relations

Personnel - PhotoCure strengthens its management team

Personnel - Proteomics company appoints new member to scientific advisory board

Personnel - Serono announces appointment of new chief financial officer

Personnel - Timothy E. Morris appointed vice president and CFO of pharmaceutical company

Personnel - Wound management/infusion company taps McConnell and Prior as CEO, COO

Pertussis - Closing schools can't contain whooping cough outbreak

Pharmaceutical Sales - Survey finds increase in turnover of pharma sales reps

Pharmacology - Cytochrome P450 4F11 characterized

Philanthropy - Foundation arranges 7,200 free eye consultations in India

Physical Activity - Regular exercise and high calcium intake optimizes bone density

Physiology - Increased maternal prepro-orexin mRNA expression may affect energy metabolism

Physiology - Markedly higher myogenin protein content found in older sedentary muscle

Physiology - Stress-related genomic responses during heat acclimation characterized

Plastic Surgery - Company announces clinical trial results for permanent injectable wrinkle filler

Pneumococcal Vaccine -  Streptococcus pneumoniae protects against fatal pneumococcal challenge

Pneumococcal Vaccine - Multiplex opsonophagocytosis assay useful to monitor pneumococcal vaccine

Pneumocystis Pneumonia - Neutrophils and ROS do not contribute to lung tissue damage in mice

Pneumonectomy - Changes in volume density estimated by CT scan parallel morphometric analyses

Pneumonia - IND submitted for aerosolized antibiotic

Pneumonia - Seniors in South Carolina urged to get pneumonia shots

Policy - Poor communities should decide their own priorities for aid

Poliomyelitis - U.N. says African conflicts, funding gap threaten polio eradication

Postpartum Depression - Recent immigration, lack of partner support, preeclampsia are risk factors

Premenstrual Dysphoric Disorder - Study finds venlafaxine an efficacious and well-tolerated treatment

Prescription Drugs - Organizations announce support for prescription drug assistance program

Prescription Drugs - Radio tags to vouch for drugs' legitimacy

Preventive Medicine - Despite setbacks, strong growth seen in $7 billion vaccine market

Primary Biliary Cirrhosis - URSO Forte launched in the U.S.

Primary Care - Most seniors switch doctors only if forced

Product Licensing - Biotech company obtains patent for key target involved in chronic pain

Product Licensing - U.S. Patent issued for nucleic acid amplification device for biological research

Product Licensing - U.S. patent granted for technology to detect nucleic acid sequences

Production Facilities - Diabetes-focused pharmaceutical company expands production in China

Professional Development - Survey suggests majority of women surgeons satisfied in their profession

Programmed Cell Death - Autocrine secreted Fas ligand promotes tumor escape mechanisms

Prostate Cancer - CD40 expression in prostate cancer is a potential diagnostic, therapeutic molecule

Prostate Cancer - HRT patches prevent the side effect of osteoporosis during cancer treatment

Prostate Cancer - Ultrasound therapy to treat prostate cancer announced by British company

Protein Kinase - Tribbles control the extent and specificity of MAPK kinase activation of MAPK

Protein Regulation - Amyloid peptides use fibroblast growth factor to activate angiogenesis

Protein Regulation - The N-terminal A domain of hepatitis B virus X protein is a negative regulator

Protein Signal - TGFbeta-related protein induces feedback regulators at poles of egg cylinder

Proteomics - A complex relationship among proteins may govern cardiac contractile performance

Proteomics - Atomistic model devised for prediction of transcription factor binding sites

Proteomics - Electroacupuncture, somatothermal stimulation can attenuate ischemic injury

Proteomics - Hedgehog signals are a prerequisite for vascular tube formation

Proteomics - Heme binding and protein stability linked in cytochrome b5

Proteomics - Recognition residues on cohesin surface mapped

Prothrombin Time Monitoring - Home PT monitoring requires sound patient selection, training, quality control

Psoriasis - Corneodesmosin gene SNP associated with psoriasis across diverse ethnic groups

Psoriasis - New breakthrough announced in "gene hunt" for skin disease

Psoriasis - Therapeutic mechanisms of efalizumab elucidated

Psychiatry - Electroconvulsive study challenged

Psychosis - Cognitive deficits are core symptoms in psychotic disorders in adolescents

Public Health - New book celebrates the nation's health workers

Pulmonary Alveolar Proteinosis - Survival rates for PAP patients has increased over 4 decades

Pulmonary Fibrosis - Th2CC chemokines play a central role in pathogenesis of pulmonary fibrosis.

Pulmonary Medicine - Dynamic elements define vascular remodeling in the pulmonary airway

Pulmonary Medicine - VEGF inactivation in the lungs launches emphysema-like findings in mice

Purchasing - Regional healthcare organization networks offer standardized supply purchasing

Quality Assurance - Computer vignette to be effective way to measure quality of physician practice

Quality Assurance - Study faults medical school for poor patient care at Dallas hospital

Quality of Life - New WHO study asks, "How happy are you with your lot in life?"

Quality of Life - WHOQOL-HIV field test instrument promising for HIV/AIDS QOL assessment

RNA Synthesis - A novel construct of the hairpin ribozyme displays RNA cleavage activity

Rankings - Nonprofit pharmaceutical company recognized by science magazine

Receptor Studies - Peripheral benzodiazepine receptor deregulation increases tumorigenicity

Recombinant Research - Tissue factor pathway inhibitor aids the antiangiogenic effects of tinzaparin

Reconstructive Surgery - Adequate venous drainage crucial for successful free jejunal transfer

Reconstructive Surgery - VEGF-C gene therapy restores lymphatic function to incisional wounds

Regulatory Issues - Pharmacists share concerns about relaxation of drug importation laws

Reimbursement - Imaging company comments on final APC rates for 2005

Renal Artery Stenosis - When renal artery stenosis is considered, high accuracy requires source images

Renal Cancer - Dendritic cell-tumor fusion vaccines being developed for renal cell carcinoma

Renal Cancer - Utility of radiofrequency ablation reviewed

Renal Disease - Data show FOSRENOL maintains bone health status during end-stage renal disease

Renal Disease - Hepatitis C treatment receives new indication in Europe

Renal Tumors - Wake Forest University completes ablate and resect study of renal tumors

Renal-Cell Cancer - Allogeneic stem-cell transplantation for renal-cell cancer reviewed

Reproductive Biology - Sperm enzyme is essential for male fertility, study shows

Reproductive Health - Studies of effectiveness of interventions with private providers are weak

Reproductive Medicine - Key oocyte-specific genes identified with novel cDNA library

Reproductive Medicine - Testis MCP expression characterized in rats

Research Funding - Wisconsin Governor unveils $750 million plan to support scientific research

Research and Markets - Avoidance of negative factors linked to mammalian cell culture technology

Respiratory Medicine - BAC-containing albuterol still dispensed in the Bronx

Respiratory Syncytial Virus - Signaling via prostaglandin receptor protects against RSV

Respiratory Syncytial virus - Respiratory syncytial virus associated with lipid-raft Hep2 cells in infection

Restenosis - Final results reported from Resten-NG AVAIL trial

Restenosis - Researchers find cilostazol may prevent restenosis in diabetics after stenting

Rheumatoid Arthritis - Study shows drug induced remission in rheumatoid arthritis patients

Rituximab - Novel assay identifies compounds that enhance rituximab anti-lymphoma activity

Rotary Blood Pumps - Physiologic control systems should ensure adequate perfusion, avoid occlusion

SARS Coronavirus - Novel SARS-CoV entry inhibitor may be a viable candidate therapy for SARS

SARS Virus - Native form of recombinant SARS coronavirus spike glycoprotein characterized

Salmonella Vaccine - Attenuated Salmonella mutants cause fatal infections in mice

Salmonella Vaccine - B7 costimulatory molecules play role in antibody responses to Salmonella

Salmonella Vaccine - Delta yej Salmonella mutants induce superior CD8+ T-cell responses

Salmonella Vaccine - Live Salmonella vaccine protects against Salmonella enteritidis

Schistosomiasis Vaccine - Vaccine protects against tetanus and schistosomiasis in mice

Secondhand Smoke - Dispute over secondhand smoke crucial in $280 billion trial

Sepsis - Cells linked to asthma and eczema also help cure deadly illness in mice

Septic Shock - FLICE-like inhibitory protein protects cells from bacterial endotoxin

Sexual and Reproductive Health - Sexual quality of life lower for the obese

Sexual and Reproductive Health - Sperm enzyme is essential for male fertility

Sick Sinus Syndrome - Atrioventricular synchronous pacing can increase ventricular load

Simian Immunodeficiency Virus - CD3/MHC-I/MHC-II/Ii surface expression modulation insufficient for SIV virulence

Simian Immunodeficiency Virus - Real-time PCR independently samples single SIV genomes from range of viral loads

Simian Immunodeficiency Virus - SIV-induced blood-brain barrier activation requires cell-associated virus

Sinusitis - All chronic sinusitis is not created equal

Skin Cancer - Learning to cover up reduces risk of skin cancer

Skin Cancer - Oxidative stress may play key role in arsenic carcinogenesis

Skin Cancer Marker - HLA A11 is marker for nonmelanomatous skin cancer risk after renal transplant

Smoking Ban - Groups plan 2006 anti-smoking initiative

Smoking Ban - Limited smoking ban gains support in Nevada

Smoking Ban - Portugal prepares to impose ban on smoking in public places

Smoking Cessation - HHS launches new initiatives to help Americans quit smoking

Smooth Muscle Cells - Ferulic acid was involved in the mitogen-activated protein kinases pathway

Spinal Cord Injury - Intrathecal baclofen-clonidine infusion system shows promise

Sports Medicine - Maximal lactate steady-state prediction must be verified by a constant-load test

Sports Medicine - U.S. FDA clears technology designed to simplify common sports-related surgery

Squamous Cell Cancer - TP53 mutations detected in squamous-cell carcinomas of conjunctiva

Staffing - Tide of new nurses rises, but shortages still loom large

Staffing Issues - Nursing journal salary survey shows continued gains for nurses nationwide

Staphylococcus - Sigma factor B required for virulence in Staphylococcus aureus

Staphylococcus Aureus - Ceftobiprole (BAL5788) moves into phase III trial

Staphylococcus Aureus - Clinical, economic challenges of Staphylococcus aureus infections demonstrated

Stem Cell Research - Angiopoietins facilitate the stages of postnatal neovascularization

Stem Cell Research - BMP signaling may control duplication of intestinal stem cells

Stem Cell Research - Btk modulates signaling in erythroid progenitor cells to enhance its expansion

Stem Cell Research - Functional liver cells developed from bone marrow-derived stem cells

Stem Cell Research - Judi R. Lum appointed CFO and VP of finance by stem cell-focused biotech company

Stem Cell Research - Louisiana Baptists affirm disapproval of gay marriage, stem cell research

Stem Cell Research - Pax5-/- progenitors differentiate into CD4+CD8+ alphabeta and gammadelta T cells

Stem Cell Research - Researchers find clues to muscle regeneration

Stem Cell Research - Stored hematopoietic stem cells can be used for a wide range of applications

Stem Cell Research - c-fos overexpression augments development/proliferation of peritoneal B cells

Stem Cell Transplantation - Impaired neuromotor function after cancer treatment can improve, study shows

Stem Cell Transplantation - Intraparenchymal NSC transplant reconstructs myelin in dysmyelinated brains

Stock Market - Antiaging products company announces delisting from NASDAQ, restructuring plans

Stock Market - Healthcare services provider announces private placement of securities

Stock Market - Pharmaceutical company announces proposed public offering, reports finances

Streptococcus Vaccine - IgA important in protecting against Streptococcus pneumoniae

Stroke - Ultrasound-aided therapy better than stroke drug alone

Substance Abuse - 2004 survey shows decline in teen drug use continues

Substance Abuse - Anti-obesity pill might fight drug abuse

Substance Abuse - Immunological changes associated with prolonged marijuana smoking

Substance Abuse - Rate of mental illness combined with drug abuse up by more than 60% in 5 years

Suicide - $6.6M grant made to support suicide prevention hotline

Surgical Menopause - Data presented on testosterone gel for surgically menopausal women

Surgical Technology - Cleaning efficacy of laparoscopic devices determined

Surgical Technology - Minnesota medical device company announces change in distributor

Surgical Technology - Technique for percutaneous catheterization of long bones developed

Survival and Mortality - Glioma gene expression profiles predict patient survival

Tardive Dyskinesia - Upswing in metoclopramide use linked with neurologic symptoms

Technology - Generic biosensor platform enables contact-free vital signs, other measurement

Technology - New family of HPLC columns for life science chromotography research introduced

Technology & Business - Market research group says U.S. biochip demand to reach $2.1 billion in 2008

Teenage Pregnancy - U.S. births to youngest teens reaches lowest level since 1946

Tetanus - Case report of tetanus in immunized, healthy adult and no point of entry

Thrombotic Thrombocytopenic Purpura - Rituximab effective in patients with refractory TTP

Thyroid Cancer - CD82 may serve as a prognostic marker of metastasis in thyroid cancer

Thyroid Cancer - Combination treatment helps thyroid cancer patients live longer

Thyroid Surgery - Etiology and diagnosis of postoperative vocal cord failure reviewed

Tirofiban - Ultrafiltration is effective for elimination of therapeutic levels of tirofiban

Tobacco Use - Federal report shows number of Iowa smokers drops

Tobacco Use - Oregon groups seek to reinstate cigarette tax

Transplant Medicine - Biopsies done a year after liver transplantation predict fibrosis progression

Transplant Medicine - Four transplants done under living kidney donor registry

Transplant Medicine - Review describes a resurgence of interest in NHBD liver transplantation

Transplant Medicine - Salvage liver transplants aid patients without proven residual liver cancer

Trauma - Language barrier increases risk of unnecessary intubation

Traumatic Brain Injury - Progesterone/allopregnanolone reduce inflammatory cytokines after TBI

Treatment - Cypher stent featured in more than 25 studies at the AHA meeting

Treatment - VNS maker reports Q2 results, makes sales targets

Tuberculosis - Pulmonary tuberculosis associated with diabetes

Tuberculosis - Tuberculosis and HIV co-infection is a symbiotic relationship

Tuberculosis Therapy - Researchers find a shorter, stable cure for murine tuberculosis

Tuberculosis Therapy - Risk factors for early relapse of tuberculosis described

Tuberculosis Vaccine - BCG can subvert monocyte differentiation into dendritic cells

Tuberculosis Vaccine - CD8 T cell activation protects against pulmonary tuberculosis

Tuberculosis Vaccine - Guidelines for latent tuberculosis testing and treatment released

Tuberculosis Vaccine - Lipoarabinomannan antibody prolongs survival of mice with tuberculosis

Tumor Suppression - GST-MDA-7 fusion protein selects for and destroys cancer cells

Tumor Suppression - Monoclonal antibody targeting kininogen domain 5 halts tumor angiogenesis

Type 1 Diabetes - Health system to develop new approaches to islet cell transplants

Type 2 Diabetes - Exenatide LAR data support initiation of phase II multidose study in 2005

Type 2 Diabetes - Pioglitazone shown to reverse thickening of carotid artery wall

Type 2 Diabetes - Western diet linked to type 2 diabetes in women

Urinary Bladder Dysfunction - Nerve growth factor gene therapy may improve diabetic cystopathy

Urological Oncology - Bladder tumors respond to non-viral tumor necrosis factor-alpha gene transfer

Urology - Diamonds are a urologist's best friend

Urology - Survivin down-regulation blocks the growth of bladder cancer cells

Uterine Leiomyomas - U.S. FDA approves new device to treat uterine fibroids

Vaccine Adjuvant - Association of antigens to ISCOMATRIX adjuvant improves CTL responses

Vaccine Adjuvant - Cannabinoid is an adjuvant and in vivo chemoattractant for dendritic cells

Vaccine Adjuvant - Vaccines that facilitate antigen entry into dendritic cells reviewed

Vaccine Development - HER-2 Protein AutoVac starts phase II trial in breast cancer

Vaccine Development - Promoters are important elements in the design of DNA vaccines

Vaccine Development - U.S. HHS buys new anthrax vaccine for stockpile

Vaccine Development - Vaccinia vector with antigen-linked calreticulin elicits an antitumor response

Vaccine Development - Vectors expressing hepatitis C virus E1 proteins display antigenicity

Vaccine Safety - Childhood vaccine finance and safety issues reviewed

Vaccinia Virus - Vaccinia virus mutants fail to initiate morphogenesis

Varicella-Zoster Virus - Epidemiology of severe varicella-zoster infection in Spain reported

Vector Development - Anionic dendrimers convey antisense oligonucleotides to cancer cell targets

Vector Development - Novel biodegradable polycation DEDA-PU gives transfection with low toxicity

Vector Development - Porcine adenoviral vectors are effective vehicles for gene delivery

Ventricular Function - Tagged MRI can be used to assess regional and global left ventricular function

Ventricular Repolarization - Routine ECGs of deaf children for repolarization anomalies may be unnecessary

Viral Vectors - Biological and physical titers should be counted in virus-based gene therapy

Viral Vectors - Modified adeno-associated virus vectors may treat Duchenne muscular dystrophy

Virology - Alternate strategies thwart the immune system's response to viral gene vectors

Virology - Forced selection of HIV-1 variant uses a non-self tRNA primer for RT

Virology - Internal controls enhance the detection of waterborne enteric viruses

Virology - Kaposi sarcoma-associated herpesvirus drives endothelial cell differentiation

Virology - Recurrent HCV does not worsen fibrosis in living donor liver graft recipients

Water Safety - Hach now testing drinking-water monitoring technology

Weight Loss - Thermogenic effect of bupropion characterized

Weight Loss - Very low-carbohydrate diets work for men and upper body fat

West Nile Virus - CDC expects mild season for mosquito-borne virus

West Nile Virus - Netherlands Vaccine Institute signs agreement to produce West Nile vaccine

Whiplash - Seat tests find poor whiplash prevention

Wilms' Tumor Gene Vaccine - Wilms' tumor gene peptide vaccine causes cancer regression

Women's Health - More aid needed to reach U.N.'s aim of reducing maternal deaths

Women's Health - Report rates health of North Dakota women

Women's Health - Report says South Carolina one of worst states for women

Women's Health - Vermont ranks No. 1 on list of best states for women

Wound Care - Cutaneous gene therapy provides wound coverage and blocks microbial growth

Wound Care - Transforming growth factor-beta antisense may prevent chronic wounds

Wound Healing - Diabetes reduces survival of random flaps in diabetes

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