Cell Biology

New tool highlights activity of key cellular signal

Published in Health and Medicine Week, December 6th, 2004

Scientists at Johns Hopkins and the University of Texas Medical Branch have created a new tool that easily reveals when and where a key cellular signal is active.

The development, described in the November 15, 2004, online edition of the Proceedings of the National Academy of Sciences, should speed identification of the signal's triggers and effects in normal processes and in conditions such as asthma, allergy, inflammation, lung disease and heart disease.

The tool - a special fluorescent protein - probes the activity of cyclic AMP in living cells and represents biology's growing application of a fluorescent phenomenon to study the molecular...

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Source: Health and Medicine Week (2004-12-06)

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