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Eating Disorder

A KCNN3 gene polymorphism may heighten susceptibility to anorexia nervosa

Published in Health and Medicine Week, January 3rd, 2005

A KCNN3 gene polymorphism may heighten susceptibility to anorexia nervosa.

According to a study from Israel, "tThe human small-conductance Ca2+-activated potassium channel gene KCNN3 has been involved in mechanisms underlying neuronal function and plasticity. A multiallelic CAG repeat polymorphism within the KCNN3 has been associated with schizophrenia and bipolar disorder. We have previously reported in a family-based study that longer CAG repeats are preferentially transmitted to patients with anorexia nervosa (AN)."

"The present study extends the analysis of KCNN3 allele distribution to a larger series of AN female patients and control groups,...

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