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Health and Medicine Week

Susan Hasty, Publisher

Table of Contents . . . January 24th, 2005

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Health and Medicine Week | Other Publications

Antioxidants - Oral antioxidants have mixed effects on UV-induced skin damage

Diabetes Therapy - Severe hypo-alpha-lipoproteinemia reported during rosiglitazone therapy

Migraine Therapy - Cost of prophylactic migraine treatments outlined

Obesity Pathogenesis - Adiponectin linked to increased weight gain in small infants

Obesity Surgery - Studies advance knowledge in obesity surgery research

Telemedicine - International Space Station uses telemedicine technology

AIDS/HIV Vaccines - New findings in the area of AIDS/HIV vaccines described

Acute Lymphocytic Leukemia - Unrelated cord blood transplantation is an option for children with ALL

Acute Myelogenous Leukemia - Clinical outcome not affected in pediatric AML patients with PTPN11 mutations

Acute Myeloid Leukemia - 57.9% of elderly acute myeloid leukemia study patients respond to chemotherapy

Acute Radiation Syndrome - Biotechnology company responds to U.S. HHS Request for Information

Addiction Medicine - Ghrelin and glucagon-like peptide studied, role of cannabinoids revealed

Addiction Medicine - Study in rats finds no connection between anxiety and alcohol use

Adenovirus - Antihexon antibody model neutralizes adenovirus

Adenovirus - Cidofovir effectively treats adenoviral hemorrhagic cystitis in HSCT patients

Adolescent Health - Study reveals high infection rate in teens for virus linked to cervical cancer

Adult T-Cell Leukemia - Adult T-cell leukemia cells down-regulate CD26 antigens via epigenetic machinery

Adverse Drug Effect - Statins induce apoptosis in rat and human myotube cultures

Adverse Drug Events - Consumer Group: Drug industry volunteer reporting plan falls short

Adverse Drug Events - Doctors must consider potentially inappropriate meds when treating elderly

Adverse Drug Events - Long-term use of NSAIDs causes severe intestinal damage

Adverse Drug Events - U.S. FDA gives scientist permission to publish Vioxx safety data

Adverse Drug Reaction - Collaborative to study unanticipated serious adverse drug events using enTRUST

Adverse Drug Reaction - EMEA to review celecoxib studies' results

Adverse Drug Reaction - Markers implicated in fatal side effects of schizophrenia drug identified

Advocacy - AIDS group to call for ban on consumer drug advertising

Aging - Activation of AMPK by in vivo hypoxia is slower than in vitro

Aging - Food intake in elderly rats studied, ineffectiveness of orexin-A revealed

Aging - Study compared isometric contractions of young and old men and women

Agriculture - Consumers benefit from organic potato breakthrough

Air Pollution - Several hazardous air pollutants exceed cancer risk level in Portland

Alcohol Use - Bipolar alcoholics helped by seizure drug

Alcohol Use - College attendance influences alcohol drinking patterns in young females

Alcohol Use - Taurine not involved in pharmacological effects of ethanol in rats

Alginate - Alginate from Sargassum spp obtained and cadmium binding studied

Allergy & Immunology - Asthma study analysis sends wrong messages, cleaning group says

Allergy & Immunology - Hay fever treatment shown to reduce symptoms by 37%

Allergy and Immunology - Thymalfasin augments the immune system's response to disease

Alzheimer Disease - Healthy cleavage: How statins protect against AD

Alzheimer Disease - Method for screening beta-amyloid secretion inhibitors developed

Alzheimer Disease - New research in the area of Alzheimer disease detailed

Alzheimer Disease - Phosphorylated eukaryotic translation factor 4E heightened in Alzheimer brain

Alzheimer Disease - Results of clinical trial of GABA(B) receptor antagonist SGS742 reported

Alzheimer Disease - Scientists develop split green for tagging protein

Alzheimer Disease - Synaptic targeting by AD-related amyloid beta oligomers provide disease clues

Alzheimer Disease - Women bear a double burden with Alzheimer disease, says resource center report

Amyotrophic Lateral Sclerosis - Neuroprotection offered by antibiotics

Anal Fissures - U.S. FDA issues not approvable letter for Cellegesic

Anemia - Anemia prevalent in cancer patients, European Cancer Anaemia Survey shows

Anesthesia - Propofol not recommended for long-term sedation of critically ill

Angiology - Beta arrestin activity studied, need for angiotensin receptor revealed

Angiology - Correlates of carotid artery stiffness in young adults reported

Angiology - H2 S produces relaxant response of resistance arteries

Angiology - Mef2c mediates vascular gene expression during endothelial cell development

Angiology - Physiological roles of angiotensin-converting enzyme 2 reviewed

Angiology - Researchers describe findings in angiology studies

Angiology - Structure of angiotensin I-converting enzyme revealed

Angiology - Thrombosis and infarction associated with collagen receptor polymorphism

Angiology - VEGF isoforms reveal a time-related response to hypoxia in the knee joint

Angiology - Vascular smooth muscle viability is pertinent to tumor biology

Angioplasty - 18 New Jersey hospitals seek permission for new heart service

Ankylosing Spondylitis - U.S. FDA approves REMICADE for patients with ankylosing spondylitis

Anthrax - Breakthrough could lead to anthrax antidote

Antibacterial Agents - Bacterial killing studied, dual role of phagocytic NADPH oxidase revealed

Antibiotics - Binding of an aminoacridine derivative to a GAAA RNA tetraloop revealed

Antifungal Activity - Chitinase from E. coli carrying Streptomyces gene is antifungal

Antimicrobials - Antimicrobial and antioxidant activities of medicinal plants reviewed

Antimicrobials - Treatment of dialysis catheter-related bacteremia reviewed

Anxiety - Stanford study shows hypnosis helps kids undergoing difficult procedure

Apoptosis - Apoptosis analyzed, resistance in regenerating hepatocytes demonstrated

Apoptosis - Fibroblast cell lines derived from LEC rats are highly susceptible to heat

Apoptosis - Pancreatic hypoplasia studied, induction and influence of nitric oxide revealed

Apoptosis - Tumor necrosis factor-alpha induces apoptosis in adrenocortical cells

Argemone Oil - Argemone oil is genotoxic

Arrhythmia - Reductions in Cx43 are associated with increased arrhythmias

Arthritis - A key signaling molecule in osteoarthritis is identified

Arthritis - Erythrocyte sedimentation rate adjusted for hematocrit and hemoglobin levels

Arthritis - Laser therapy is an alternative to VIOXX for arthritis sufferers

Arthritis - Renal amyloidosis complicating rheumatoid arthritis treated with etanercept

Aspergillus - Intake of rice with Aspergillus and polybrominated diphenylethers studied

Assisted Reproduction - Biopharmaceutical company receives CE Mark for Cumulase

Assisted Reproduction - Estradiol and testosterone levels in follicular fluid predict oocyte maturity

Assisted Reproduction - Genes expressed during ovarian hyperstimulation may not affect implantation

Assisted Reproduction - Growth differentiation factor gene fragments treat porcine ovarian dysfunction

Asthma -  S. mansoni-infected asthma patients produce lower levels of Th2 cytokines

Asthma - Indiana health agency plans 5-year attack on asthma

Astrocytoma - Chromosomal aberrations identified in diffuse astrocytomas

Astronomy - Scientists observe largest explosion in space

Atheroscerlosis Risk Factors - Caloric restriction significantly improves insulin sensitivity

Atherosclerosis - Atherogenic Western diet enhances intestinal MTP gene expression

Atherosclerosis - COX-2-derived prostacyclin confers atheroprotection on female mice

Atherosclerosis - Cholesterol acyltransferase 2 have opposite atherosclerotic potential

Atherosclerosis - HB-EGF can play an integral role in atherogenesis

Atherosclerosis - Hepatic lipase can have a variable effect on atherosclerosis

Atherosclerosis - Reduced progression of plaques tied to statin drugs

Atherosclerosis - Stent-based gene therapies offer a strategic way to treat arterial disease

Atherosclerosis - Studies add new findings to atherosclerosis body of knowledge

Atopic Dermatitis - EWGAD issues clinical guidance on use of topical calcineurin inhibitors

Atrial Fibrillation - CE Mark clearance granted for the surgical ablation system

Atrial Fibrillation - Clinical trial enrollment announced for radiofrequency ablation technology

Atrial Fibrillation - Dual-chamber pacemakers worth extra cost, study finds

Atrial Fibrillation - Study investigated mechanism of atrial dilatation during fibrillation

Atrial Fibrillation - Ximelagatran is as effective as warfarin for stroke prevention

Autism - Mayo Clinic study suggests no link between autism and immunizations

Autism - Wealthier school systems more likely to diagnose autistic kids

Autoimmune Diseases - Positive results reported in phase I/II trial with HuMax-Inflam/MDX-018

Awards - Disease management company wins Best Disease Management Program: Medicare award

Awards - Shanghai chemistry R&D services company recognized for excellence by government

Awards - WaterHealth inventor receives $50,000 Affymatrix award for potable water device

Awards - Winners of 2004 Life Science Industry Awards announced

Bacteriology - Effect of oxalic acid on bacterial regrowth in drinking water studied

Bacteriology - Modeling of therapies targeted at bacterial quorum sensing described

Bacteriology - Molecular aspects of Corynebacterium glutamicum urea uptake revealed

Bacteriology - Polychlorinated biphenyls degraded by newly isolated aerobic bacterium

Bacteriology - Secretion of bacterial effectors studied, raft-mediated triggering revealed

Bacteriology - Spectroscopic quantification of bacteria using neural networks reported

Behavior - Two self-fulfilling prophecies are stronger, and more harmful, than one

Benzene - Xenobiotic metabolism and mechanism of benzene toxicity reviewed

Beryllium Disease - Sensitized people should be monitored for eventual granulomatous disease.

Bile Ducts - Ligated bile duct secretion modulated by alpha-1 adrenergic receptor agonists

Biochemistry - Study examined effects of surfactants on acid phosphatase denaturation

Biological Therapy - DNA decontamination protocols will enhance the value of cell and gene therapies

Biomarkers - Biomarkers valuable for risk assessment in molecular epidemiology of cancer

Biomedical Engineering - Companies sign process development and manufacturing agreement for blood enzyme

Biomedical Engineering - Matrix-bound ligand boosts local neovascularization

Biomedical Engineering - Medical device company introduces tapered stem hip system

Biomedical Engineering - Stem cell-focused company targets cardio patients for adult stem cell therapy

Biomedical Engineering - Whole genome amplification kit introduced by life sciences high tech company

Biotechnology - Modular protein tolerance to alteration of internal repeats clarified

Biotechnology - Novel microspheres can reversibly transform into vesicles

Biotechnology - Simultaneous tether extraction stabilizes neutrophil rolling under high stress

Bioterrorism - Bacterial biomarkers identified by chromatography correlate with Gram stain

Birth Defects - January 24-30, 2005 is Folic Acid Awareness Week

Birth Defects - Maternal nutritional status affects fetal risk of developing orofacial cleft

Bladder Cancer - No association between inorganic arsenic concentration and bladder cancer risk

Blood Supply - Blood donations needed for winter months

Body Composition - Body fat values from anthropometric methods and impedance compared

Bone Repair - Hydrolysis treatment improves anionic collagen scaffolds for bone repair

Botany - Scientists crack secret PIN controlling plant development

Bovine Spongiform Encephalopathy - Canada, U.S. safeguards provide protection against BSE, USDA official says

Bovine Spongiform Encephalopathy - Farm Bureau funds full seat on meat export board

Bovine Spongiform Encephalopathy - Mad cow case poses no public health threat, Canadian minister says

Brain Injury - Group lauds vehicle safety leadership efforts in 2004

Breast Cancer - Adenosine is a breast carcinoma cell mitogen

Breast Cancer - Adjuvant HT or chemotherapy choice should be offered to women with ER+ tumors

Breast Cancer - Angiogenic profiles of breast carcinomas expose leukocyte penetration

Breast Cancer - Anti-aromatase coumarin derivative characterized

Breast Cancer - Breast cancer may be uniquely sensitive to inhibitors of PI3K pathway

Breast Cancer - CT laser mammography distributor selected for Czech Republic

Breast Cancer - Chemotherapy and long-term outcome compared between lobular and ductal disease

Breast Cancer - Drugs induce superinvasive phenotype in breast cancer cells

Breast Cancer - Insulin receptor substrate is involved in mammary tumor metastasis

Breast Cancer - Mammograms probably don't cause much more biological damage than hard X-rays

Breast Cancer - Mammography archived at Univ. of Pennsylvania Health System

Breast Cancer - More frequent mammography for women on HRT suggested

Breast Cancer - New findings in breast cancer described

Breast Cancer - New findings in the area of breast cancer described

Breast Cancer - New research in the area of breast cancer detailed

Breast Cancer - Pharma company updates breast cancer research results from 2004 symposium

Breast Cancer - RT-PCR detects disseminated epithelial cells in BM of breast cancer patients

Breast Cancer - Radiotherapy, susceptibility may increase risk after childhood Hodgkin disease

Breast Cancer - Reports describe recent advances in breast cancer research

Breast Cancer - Researchers call for new approach to clinical trials in postgenomic era

Breast Cancer - Statins may have anticarcinogenic effects in older women

Breast Cancer - Studies describe new findings in breast cancer research

Breast Cancer - U.S. FDA clears use of automated scanning system for PathVysion DNA

Breast Reconstruction - Tissue expander colonization not linked to capsular contracture

Bronchopulmonary Dysplasia - Survivors of BPD go on to develop chronic airflow obstruction

Burkholderia - Patterns of genomic variation in Burkholderia species identified

Burns - Cement burns may have resulted from insufficient information, warnings

Business & Finance - Cell based technologies market research study released

Business & Finance - Concurrent Pharmaceuticals changes name, secures $34 million in financing

Business & Finance - Genelabs gets $1.25M for amendment to DNA amplification technology license

Business & Finance - Guilford completes sale and leaseback; receives $19.4M in net proceeds

Business & Finance - HIPAA alters pharmaceutical company rep strategy

Business & Finance - HIV test maker sees Q4 revenue, margin gains; 140% increase in HIV product sales

Business & Finance - Health insurer donates $100,000 to tsunami relief efforts

Business & Finance - Institutional pharmacy provider commented on proxy statement

Business & Finance - Medical software company added to American Stock Exchange, names board members

Business & Finance - Medical technology company closes public offering, appoints directors

Business & Finance - Microelectronics company receives NASDAQ noncompliance notice

Business & Finance - Near-infrared instruments developer announces financing

Business & Finance - Pain management company provides financial guidance for 2005

Business & Finance - Pharma company provides support to relief effort in Asia

Business Update - Abbott and Genentech ranked among top 10 pharmaceutical sales forces

Business Update - Autologous platelet rich plasma preparation system launched

Business Update - Biopharmaceutical firm announces relocation

Business Update - Biopharmaceutical firm announces result of meeting

Business Update - Biotech company completes European Mutual Recognition Procedure

Business Update - Biotechnology company announces sale and leaseback transactions

Business Update - Box Elder County in Utah might sell nursing home

Business Update - Catholic health systems plan to integrate laboratory services

Business Update - Children's hospital enters agreement for blood pressure monitoring technology

Business Update - Company announces favorable rulings in stent patent infringement case

Business Update - Company expands mite rearing, processing facility

Business Update - Contract research organization signs agreement for clinical monitoring services

Business Update - Cosmetic dentistry laboratory launches new Web site

Business Update - DENTSPLY acquires a compound for protection of tooth structure

Business Update - Device firm announces phase II of its productivity initiative

Business Update - Disintegrator needle-destruction device commences global distribution

Business Update - Fixed-site laser vision correction services provider opens Utah center

Business Update - ForHealth Technologies transitions manufacturing of IntelliFill i.v.

Business Update - Four Rivers Software announces six distribution partners

Business Update - Generic pharmaceutical company announces filing of ANDA with U.S. FDA

Business Update - GeoPharma shares launch strategy for Mucotrol

Business Update - Gordian wins 22 contracts in 6 months

Business Update - Government services provider awarded pharmacy services contract

Business Update - Growers planting Pioneer brand Sorghum Hybrids win 10 categories in NGSP contest

Business Update - HealthSouth signs settlement agreement regarding Medicare billing practices

Business Update - Healthy foods company introduces new CEO, discusses growth plans in 2005

Business Update - Horizon Health leases Laurelwood Hospital of Ohio

Business Update - ICL Fertilizer to change sources of phosphate rock to improve profitability

Business Update - IDX Carecast earns second SCP certification

Business Update - IPC-The Hospitalist Company expands practice into North Carolina

Business Update - Light-based devices manufacturer announced 150th shipment of Lumenis

Business Update - Medical device company consolidates manufacturing capabilities

Business Update - Medical devices component provider extends agreement with St. Jude Medical, Inc.

Business Update - Medical heart-assist device company announces status of U.S. SEC filing

Business Update - Nashville selects provider for Public Access Defibrillation program

Business Update - Natural skin care products company begins manufacturing core offerings in Canada

Business Update - Nonprofit hospitals in Brownsville, Pennsylvania, weigh in on hospital proposal

Business Update - Norak Biosciences changes name

Business Update - Orthopedic device company signs 3-year contract with hospital supply group

Business Update - PROCLEIX ULTRIO Assay approved for use with PROCLEIX TIGRIS System

Business Update - Patient services company consolidates corporate offices

Business Update - Pharma firm to divest its plasma products business to U.S. investors

Business Update - Pharmaceutical firm adopts renewed shareholder rights plan

Business Update - Pharmaceutical group selects software company's quality management system

Business Update - Report shows high-content screening market not dominated by any one company

Business Update - Reports indicate Bristol-Myers may sell its consumer drug line

Business Update - Research on CO2 flux system presented at conference

Business Update - State approves expansion of south Georgia hospital

Business Update - Subsidiary granted marketing rights for Neovastat

Business Update - Technology company awarded five contracts for mental health management services

Business Update - U.S. EPA to use chemogenomics platform to predict potential chemical toxicity

Business Update - Weight loss clinic opens in Texas

Business and Finance - White paper issued on measuring accountability of hospital marketing

Cadmium Exposure - Increased cadmium exposure may influence occurrence of disease

Cancer Genetics - Loss of BRCA1 function associated with sensitivity to DNA-damaging chemotherapy

Cancer Genetics - Recent findings in cancer genetics provide new insights

Cancer Risk - Elevated glucose levels and diabetes associated with risk for cancer

Cancer Surgery - Complications of free flap head and neck reconstruction reviewed

Cancer Survival - Reduced health care access and ability to pay decrease cancer survival

Cancer Therapy - Additional information provided to U.S. FTC for melanoma treatment

Cancer Therapy - Angiogenesis inhibitors antagonize lymphoma proliferation

Cancer Therapy - Breast cancer patients boost quality of life with vaginal moisturizer

Cancer Therapy - Brochures help cancer patients make informed treatment decisions

Cancer Therapy - Cancer coalition donates medical goods

Cancer Therapy - Clolar wins FDA approval for common pediatric leukemia

Cancer Therapy - Data on successful treatments for lymphoma with few side effects presented

Cancer Therapy - Free makeovers at Alabama hospital boost spirits of cancer patients

Cancer Therapy - IND filed with U.S. FDA for AP5346

Cancer Therapy - Imaging study of dogs offers insight into 9/11 resulting cancers

Cancer Therapy - New treatment for cancer of the larynx at available at medical center

Cancer Therapy - Protein arginine methyltransferase complexes regulate tumor suppressor genes

Cancer Therapy - Quinolones enhance antitumor activity of ultrasonic irradiation

Cancer Therapy - Research in cancer therapy provides new insights

Cancer Therapy - Researchers detail new studies and findings in the area of cancer therapy

Cancer Therapy - Researchers publish new studies and findings in the area of cancer therapy

Cancer Therapy - Residual tumor cells are a barrier to targeted cancer therapeutics

Cancer Therapy - Study examines target for blocking new lymphatic growth

Cancer Therapy - Trial: IRESSA failed to significantly prolong survival in comparison to placebo

Cancer Therapy - Tumor cells resistant to hemiasterlin analogue characterized

Cancer Vaccines - Biopharmaceutical company announces survival data of trial with cancer vaccine

Cancer Vaccines - Findings advance knowledge in cancer vaccines research

Cancer Vaccines - Reports add new data to cancer vaccines research

Cancer Vaccines - Researchers' findings advance cancer vaccines research

Cancer Vaccines - Studies add new findings to cancer vaccines body of knowledge

Cancer Vaccines - Studies advance knowledge in cancer vaccines research

Candidemia - Antifungal medicine VFEND receives U.S. FDA approval for blood infection

Candidiasis - CaMIT1 inactivation reduces Candida albicans virulence

Carcinogenesis - Reports describe recent advances in carcinogenesis research

Cardiology - "Annexin A5 resistance" is a mechanism for thrombosis in aPL syndrome

Cardiology -  TrxR2 plays a pivotal role in both hematopoiesis and heart function

Cardiology - Anatomic factors influence slow pathway conduction

Cardiology - Compensated hypertrophy is associated w/ preserved myocardial function

Cardiology - Early aortic remodeling in hypertensive rats may have genetic origins

Cardiology - Effects of junctin overexpression on Ca2+ vary with age

Cardiology - Endogenous inhibitory factor NCXIF is a reasonably potent blocker

Cardiology - Findings describe new data in cardiology research

Cardiology - Findings in cardiology provide new insights

Cardiology - Incubation of aorta produces reduction in agonist-evoked contraction

Cardiology - Mechanisms of reduced cardiac function after brain death are reviewed

Cardiology - Model reproduces experimental results for Ca2+ handling in myocytes

Cardiology - New data illuminates research in cardiology

Cardiology - New findings in the area of cardiology described

Cardiology - New research in the area of cardiology detailed

Cardiology - Oxidative stress plays a role in clomipramine-induced cardiotoxicity

Cardiology - Postprocedural creatinine increase was a predictor of late mortality

Cardiology - Preconditioned hearts may inhibit F0 1 ATP synthase activity

Cardiology - Report describes perioperative diagnosis of cardiac risk patients

Cardiology - Researchers detail new studies and findings in the area of cardiology

Cardiology - Researchers provide details of new studies and findings in the area of cardiology

Cardiology - ST-segment depression is associated with the magnitude of ischemia

Cardiology - Structures may elucidate mechanisms of volvatoxin A2 and Cyt toxins

Cardiology - Study fails to demonstrate myocardial protective effects of clevidipine

Cardiology - Study investigated PKC isoforms in ischemic preconditioning

Cardiology - Study tested whether treatment with tedisamil affects cardiac growth

Cardiology - Superoxide dismutase protected endothelium in ischemia-reperfusion

Cardiology - Synaptic dysfunction may be an early marker for neuronal cell death

Cardiology - Tirofiban reduced the risk for death, MI, and refractory ischemia

Cardiology - Transplanted bone marrow cells generate angiogenic factors in the heart

Cardiomyopathy - Medical device company announces results of study in hypertrophic cardiomyopathy

Cardioprotection - Cardioprotection of erythropoietin is linked with apoptosis inhibition

Cardioprotection - Report describes mechanisms of cardioprotection afforded by K/Mg + DZX

Cardiopulmonary Bypass - Miniaturized extracorporeal circulation system reduces morbidity

Cardiopulmonary Bypass - Surgeon can test occlude to identify vessel to be ligated

Cardiovascualr Research - Hyperosmolality regulates atrial myocytic ANP release

Cardiovascular Disease - Complication risk with coronary catheterization low in moderate obesity

Cardiovascular Disease - Position article on cardiac surgery risk models released

Cardiovascular Research - Ang II-mediated pressor responses are mediated via V1 receptors

Cardiovascular Research - Decrease in preload during recovery may be prevented by CV mechanisms

Cardiovascular Research - Genetic background affects features of breathing during sleep

Cardiovascular Research - H+ stimulates acid-sensing ion channels to evoke reflex response

Cardiovascular Research - Heliox breathing improves high-intensity exercise endurance capacity

Cardiovascular Research - Higher BP was associated with high risk of severe white matter lesions

Cardiovascular Research - Increased BP suggests increased vascular resistance during feeding

Cardiovascular Research - Losartan effects on fetal CV regulation differ by brain region

Cardiovascular Research - Midodrine improves the recovery of beat-to-beat BP after exercise

Cardiovascular Research - Ouabain and Na pump interact in the caveolar domain

Cardiovascular Research - Pioglitazone attenuates collagen type I synthesis in fibroblasts

Cardiovascular Research - Stress response is induced by decompression sickness

Cardiovascular Research - Study investigated effects of hyperhomocysteinemia

Cardiovascular Research - Study investigated muscle sympathetic nerves during orthostatic stress

Cardiovascular Research - Study investigated selective muscle mechanoreceptor activation

Cardiovascular Research - Study supports evidence of gating-induced changes in Phe656 side chains

Carotid Artery Disease - Pros, cons of endarterectomy considered in women with symptomatic ICA stenosis

Carpal Tunnel Syndrome - Workers with repetitive-motion problem find relief with night-time splinting

Cartilage Repair - Biphasic scaffold developed for cartilage tissue engineering

Cation Transporter - Organic cation transporter hOCT1 analyzed, regulation revealed

Cell Biology - Binding site for antimitotic peptides identified on beta-tubulin

Cell Biology - Interferon-gamma and interferon-alpha have opposing effects on stellate cells

Cell Biology - Proteomic gate-keepers regulate the outcomes of senescent cells

Cell Biology - Research yields cellular snapshot of protein flux

Cell Biology - Researchers discover how serum factors prevent TRAIL-induced apoptosis

Cell Biology - Researchers tease out one critical role of tumor-suppressor gene

Cell Biology - Study of hypoxia and new gene reveals early-stage action of p53 gene

Cell Biology - VEGF increases the availability of channels used for paracellular transport

Cell Differentiation - Claudin localization is regulated in developing by fetal alveolar epithelia

Cell Research - C-terminally truncated Cx43K258stop mice lack functions of Cx43

Cell Research - E2F-1 is a potential target in treatment of myoblast hypertrophy

Cell Research - Model predicts that cell growth rate relates to surface area at birth

Cell Research - Results suggest dimerization mechanism for mitochondrial ATP synthase

Cell Research - Study investigated fluctuations in mitochondrial membrane potential

Cerebrovascular Disease - Genes delivered following cerebral infarction improve neurological outcomes

Cerebrovascular Disease - Homeobox D3 gene delivery initiates cerebral angiogenesis in mice

Cervical Cancer - Exposure to secondhand smoke increases risk of developing cervical tumors

Cervical Cancer - January 2005 is Cervical Cancer Screening Month

Cervical Cancer - Recent studies add new data to cervical cancer research

Cervical Cancer - Reports advance knowledge in cervical cancer research

Chagas Disease -  Trypanosoma cruzi gene structure does not sway drug susceptibility

Chlamydia - Candidate NAD+ transporter in bacterial symbiont identified

Chlamydia trachomatis - Hematopoietic cells needed to initiate specific CD8+ T-cell response

Cholesterol - Cholesterol drug co-administered with fenofibrate study results reported

Cholesterol - Other lipids besides LDL-C influence cardiovascular health

Chromatin - Condensation of chromatin studied, role of cations clarified

Chronic Liver Disease - Angiotensin II receptor antagonist treats nonalcoholic steatohepatitis

Chronic Pain - U.S. FDA approves ziconotide intrathecal infusion for severe chronic pain

Cirrhosis - Research offers hope of new treatments for liver damage "plague"

Climate Change - Antarctic iced over because of greenhouse gases - not ocean currents

Clinical Trails - Phase II trial of HyCAMPTM initiated for colorectal cancer

Clinical Trials - Company provides update on cancer and HIV clinical-development programs

Clinical Trials - DATATRAK to provide technology solutions for clinical trials

Clinical Trials - Race may influence the response to recombinant HIV-1 gp120 vaccines

Clinical Trials - Results of autoimmune therapy in healthy volunteers study released

Clinical Trials - Synthetic antibodies manufacturer announces phase 1 trial

Coagulation - Coagulation factor Va analyzed, enhanced cleavage by protein C revealed

Cochlea - Noise perception of mice analyzed, role of spiral ganglion responses revealed

Collaborations - ActiveHealth Management works with Aetna on chronic care program

Collaborations - Agreement signed for transdermal treatment for major depressive disorder

Collaborations - Alliance formed for Canvaxin for melanoma

Collaborations - Blue Cross Blue Shield of Georgia joins Anthem Blue Cross and Blue Shield

Collaborations - Companies agree to terminate dormant joint venture

Collaborations - Companies to commercialize INTERCEPT system for plasma in Asian region

Collaborations - Deal signed for development of osteoporosis and bone loss therapy

Collaborations - Device company forms partnership with TDC Medical

Collaborations - Device firm strengthens presence in Southeast Asia, China

Collaborations - Discovery program launched to combine antibody technologies

Collaborations - Drug discovery company announces collaborations

Collaborations - GPC Biotech announces achievement of milestones totaling $1.2M

Collaborations - Joint venture formed to develop fixed-dose combination of three HIV medicines

Collaborations - Library deal signed with Sanofi-Synthelabo Recherche

Collaborations - Neugene antisense deal signed with Walter Reed Army Institute of Research

Collaborations - New anti-angiogenesis program added to collaborative agreement

Collaborations - Pharmaceutical firm acquires exclusive rights to Nordette

Collaborations - Pharmaceutical firm signs supply agreement with Ceph International

Collaborations - Pharmaceutical firms team up to develop diabetes treatments

Collaborations - Research alliance formed to develop compounds for metabolic disease

Collaborations - Supplier agreement signed with Bausch & Lomb for viscoelastic products

Collaborations - Trisenox financing agreement signed

Colon Cancer - Breakthrough cancer treatment Avastin approved in Switzerland

Colon Cancer - CHOP regulates ER stress-induced apoptosis by enhancing DR5 expression

Colon Cancer - Integrated therapies show promise for treating colorectal cancer

Colon Cancer - Long-term consumption of red and processed meat linked with cancer risk

Colon Cancer - System detects colon polyps in colons previously obscured by fluid

Colorectal Cancer - APAF-1 gene dysfunction from allelic imbalance increases with tumor progression

Colorectal Cancer - Colorectal cancer detected by quantitative fluorescence of stool DNA

Colorectal Cancer - Data advance knowledge in colorectal cancer research

Colorectal Cancer - HNPCC predictive genetic testing does not cause adverse psychological outcomes

Colorectal Cancer - High dietary intake of magnesium may help reduce women's risk

Complementary & Alternative Medicine -  Tinospora cordifolia restores antioxidant function in diabetic organs

Complementary & Alternative Medicine - Chamomile tea: New evidence supports health benefits

Complementary & Alternative Medicine - Green tea flavonoid may lower the invasive potential of prostate cancer

Complementary & Alternative Medicine - HealthSaver offers discounts on alternative health care products

Complementary & Alternative Medicine - Natural tea supplement viable option for slowing Alzheimer disease

Complementary & Alternative Medicine - Research shows omega-3 fats feed the human brain, not the hips

Congestive Heart Failure - Collaboration to develop AAV-based gene therapies for congestive heart failure

Congestive Heart Failure - First U.S. implantation of a biventricular pacemaker for the AVAIL CLS/CRT study

Congestive Heart Failure - Heart failure registry shows differences in Hispanic Americans' health status

Congestive Heart Failure - Study pinpoints protein's role in heart failure prevention

Contraception - Getting pregnant while on the pill: another health hazard of being overweight

Coronary Artery Disease - Trial to evaluate skin sterol values and new coronary artery disease markers

Coronary Heart Disease - Middle-aged women with relatively high heme iron intake have increased CHD risk

Coronary Heart Disease - Report: Catheters set to play an expanding role in interventional cardiology

Correction - Medifast to purchase Xerox's DocuColor iGen3 Digital Production Press

Correctional Health - Inmate infections spreading, officials warn of public health risk

Correctional Health - Many Minnesota state prisoners have "meth mouth"

Cosmetic Surgery - Clear Channel criticized over contest that granted breast surgery

Cosmetic Surgery - Cosmetic procedures are gaining popularity among men

Critical Care Medicine - Bonfils fiberscope effective for management of difficult intubation

Critical Care Medicine - Laryngeal tube insertion not feasible during manual in-line neck stabilization

Critical Care Medicine - Microbial keratitis may be occupational hazard for ITU staff

Crohn's Disease - Serum and local levels of sRANKL and OPG are increased in CD

Crosslinking - Carbodiimide-crosslinked HA/collagen membrane safe and effective antiadhesive

Cryptosporidium - Cyclospora oocysts are not ingested by the nematode Caenorhabditis elegans

Cystectomy - Robotic radical cystectomy for managing bladder cancer reviewed

Cystic Fibrosis - Airway prostasin is therapeutic target in cystic fibrosis

Cystic Fibrosis - Biopharma company announces phase 1 study for PTC124

Cystic Fibrosis - Golf tournament raises money for cystic fibrosis foundation

Cystic Fibrosis - Results help to interpret nasal potential differences in animal models

Cytomegalovirus - Initiation of HCMV lytic replication involves transcriptional activation

Cytoplasmic Body Myopathy - Cytoplasmic body myopathy analyzed, similarity to motor neuron disease revealed

DNA - DNA molecules have increased binding affinity for human prourokinase

DNA Research - Mitochondrial transcription factor A maintains human mitochondrial DNA

DNA Research - Novel bleomycin conjugates cleave double-stranded DNA

DNA Research - Processive DNA methylation occurs preferentially at hemimethylated target sites

DNA Research - Telomere damage and shortening rate in fibroblasts reduced by L-carnosine

DNA Transcription - RNA polymerase mutant deficient in DNA melting useful in study of activation

Dairy Science - Skeletal tissue growth rates increased in prepubertal dairy heifers

Defibrillation - Virtual electrodes do not explain mechanism of defibrillation

Dementia - Weight loss may be an early sign of dementia in the elderly

Depression - Doctor's death calls attention to depression

Depression - European drug review group meets on paroxetine and other SSRIs

Depression - U.S. FDA grants ANDA for generic citalopram hydrobromide tablets for depression

Dermatology - Antikeratin monoclonal antibody generated

Dermatology - Communications provider invests in beauty

Dermatology - Company receives CE Mark for new cosmetic dermal filler

Dermatology - Genetic characterization of epidermolysis bullosa should improve diagnoses

Dermatology - Genomic response to asiaticoside in fibroblasts clarified

Dermatology - Keratinocyte growth and differentiation factors guide drug investigation

Dermatology - Non-healing ulcers signal the possibility of factor V Leiden mutation

Dermatology - Non-viral gene therapy may help patients with skin disorders

Dermatology - Novel keratinocyte protein linked to wound healing

Dermatology - Phase II trial of AVAC fails to meet the primary efficacy endpoint

Dermatology - Researchers' work adds to dermatology body of knowledge

Dermatology - Semaphorin 3F prohibits melanoma metastasis

Developmental Biology - Zebrafish may hold key to understanding human nerve cell development

Diabetes Complications - Lipid lowering agents may reduce the risk for diabetes-related vision loss

Diabetes Complications - No blind mice, thanks to stem cell scientists

Diabetes Complications - Pancreatic islets from type 2 diabetic patients have functional defects

Diabetes Complications - TNF-alpha release negatively associated with apolipoprotein B

Diabetes Genomics and Genetics - Biethnic comparisons of autosomal genomic scan for loci linked to adiponectin

Diabetes Genomics and Genetics - Insulin-like growth factor-II receptor gene linked to type 1 diabetes

Diabetes Genomics and Genetics - Lymphoid tyrosine phosphatase locus associated with type 1 diabetes

Diabetes Genomics and Genetics - Mutations in KCNJ11 gene rare in type 1 diabetes diagnosed before 2 years

Diabetes Genomics and Genetics - Protein tyrosine phosphatase polymorphisms linked to glucose homeostasis

Diabetes Genomics and Genetics - Variation in NCB50R does not contribute to nonautoimmune diabetes

Diabetes Pathogenesis - Biological importance of peptides of calcitonin family examined

Diabetes Pathogenesis - Fas deficiency prevents type 1 diabetes via T-cell hyporesponsiveness

Diabetes Pathogenesis - Findings describe new data in diabetes pathogenesis research

Diabetes Pathogenesis - Hyperglycemia induces vagally mediated increase in C-peptide secretion

Diabetes Pathogenesis - PPAR-gamma overexpression suppresses insulin secretory capacity in islets

Diabetes Pathogenesis - Phosphatidylinositol 3-kinase inhibitors reveal enhanced insulin secretion

Diabetes Pathogenesis - Platelet-derived growth factor stimulates glucose transport in muscles

Diabetes Pathogenesis - Research in diabetes pathogenesis provides new insights

Diabetes Pathogenesis - Researchers publish new studies and findings in the area of diabetes pathogenesis

Diabetes Pathogenesis - Serine phosphorylation promotes insulin resistance

Diabetes Pathogenesis - Studies advance knowledge in diabetes pathogenesis research

Diabetes Research - Agreement signed to secure embryonic stem cell technology for diabetes research

Diabetes Risk Factors - Gamma-glutamyltransferase predicts risk of type 2 diabetes

Diabetes Therapy - Activated protein C preserves islet mass after intraportal transplantation

Diabetes Therapy - Affinity chromatography of insulin with heptapeptide ligand reported

Diabetes Therapy - Amylase inhibitor from kidney beans has hypoglycemic activity

Diabetes Therapy - Dual-wave bolus feature in insulin pumps better at controlling hyperglycemia

Diabetes Therapy - Free radical scavenger protects against glucose-induced cell dysfunction

Diabetes Therapy - Glibenclamide treatment effective in permanent neonatal diabetes

Diabetes Therapy - Glycoinsulins possess prolonged blood-sugar-lowering activity

Diabetes Therapy - New findings in diabetes therapy described

Diabetes Therapy - Phloridzin improves hyperglycemia but not hepatic insulin resistance

Diabetes Therapy - Pioglitazone restores impaired glucose-stimulated insulin secretion

Diabetes Therapy - Proteins released by islets affect islet engraftment in type 1 diabetes

Diabetes Therapy - Reports describe recent advances in diabetes therapy research

Diabetes Therapy - Short gastric veins unsuitable for pancreatic islet transplantation

Diabetes Therapy - Simvastatin restores vasoconstriction via effects on oxidizing metabolism

Diabetes Therapy - Synthetic polymer stimulates insulin release from RINm5F insulinoma cells

Diabetes Type 2 Complications - Obesity and metabolic syndrome powerful predictors of diabetes type 2

Diabetic Ketoacidosis - Transcriptome and proteome expression in activated T lymphocytes described

Diabetic Nephropathy - Kidneys from nonobese diabetic mice analyzed in non-diabetic stage

Diabetic Nephropathy - New findings in the area of diabetic nephropathy detailed

Diabetic Neuropathy - Alpha-lipoic acid provides neuroprotection in diabetic rats

Diabetic Neuropathy - Hyperglycemia attenuates nerve conduction velocity in male rats

Diabetic Neuropathy - Venlafaxine provides complete pain relief in acute diabetic neuropathy

Diabetic Retinopathy - Combined risk factors accelerate vision complications in diabetics

Diagnostics - Anemia self-screening kit now available

Diagnostics - Antimicrobial exposure suitable for diagnosis of surgical site infections

Diagnostics - Catholic University in Rome receives CTLM system

Diagnostics - Company chosen to launch thyroid disease detection device

Diagnostics - Delphi Medical will manufacture vision-testing equipment

Diagnostics - Diagnosis and monitoring of syncope reviewed

Diagnostics - FDA 510(k) clearance granted for BioZ Dx

Diagnostics - Fluorescent ligation detection assay identifies leukemia translocations

Diagnostics - Hair analysis divulges the ingestion of toxic weight loss products

Diagnostics - Homogeneous competitive-type immunoassay for insulin developed

Diagnostics - Methods to analyze irradiated spicy vegetables described

Diagnostics - Microarray system cleared by U.S. FDA

Diagnostics - Neural networks used as statistical tools in epidemiological studies

Diagnostics - Niris System receives market clearance from U.S. FDA

Diagnostics - Photoswitchable cyan fluorescent protein developed for protein tracking

Diagnostics - Radiation sensitivity of Aspergillus flavus in beef jerky reported

Diagnostics - Tandem-repeated DNA probe based amplification simplifies gene detection

Diagnostics - U.S. FDA clears standalone APTIMA test to detect chlamydia trachomatis

Diagnostics - Universal procedure exposes DNA and RNA targets in whole blood

Dialysis - Dialysis company inks contract in Romania

Diet & Nutrition - Clinical trials planned for new dietary supplement candidates

Diet & Nutrition - Company ships natural diet products to GNC for 2005 diet season

Diet & Nutrition - Diets higher in dairy, fruits, and vegetables may address pediatric hypertension

Diet & Nutrition - Don't count on vitamin C to boost your exercise performance

Diet & Nutrition - Elementary school awarded 3-A-Day of Dairy Nutrition Education Grant

Diet & Nutrition - How much water is enough during exercise?

Diet & Nutrition - Magazine names Seattle fittest city; Houston fattest

Diet & Nutrition - Man who lost more than 450 pounds scheduled to go home

Diet & Nutrition - New Hanover schools to end fried foods, serve healthier lunches

Diet & Nutrition - New ebook discusses alternative therapy to reverse chronic disease

Diet & Nutrition - Research forecasts low-carbohydrate market surge in first quarter of 2005

Diet & Nutrition - Survey shows New Year's resolutions focus on wellness over weight loss

Diet & Nutrition - Survey shows adults face obstacles in getting nutritious, good-tasting meals

Diet & Nutrition - Survey shows women are striving for balance in their diet

Diet & Nutrition - Univ. of Massachusetts study aims at keeping middle school students slim

Diet & Nutritoin - Weight loss strategies work in people with prediabetes

Diet and Nutrition - Dietary fiber from barley possesses anti-mutagenic activity

Diet and Nutrition - Mechanism of olive oil's protective effect against breast cancer determined

Diet and Nutrition - Plasma glucose doesn't alter food restriction-induced hepatic gene expression

Diet and Nutrition - Review finds slim data on diet plans

Diet and Nutrition - Study finds eating fruits, vegetables doesn't reduce breast cancer risk

Diphtheria - Proteins required for biosynthesis of diphthamide identified

Disaster Relief - Catholic Healthcare West contributes $250,000 to tsunami relief

Disaster Relief - Company donates water purification tablets for earthquake/tsunami disaster

Disaster Relief - Nonprofit supplier sends medical emergency kits to disaster areas in Asia

Disaster Relief - U.S. HHS to lead emergency public health, medical response for major disasters

Disease Associations - CRP levels appear only marginally associated with dietary, lifestyle factors

Disease Associations - Hypothyroidism is common in Turner syndrome

Domestic Violence - Prevalence among pregnant women found higher upon midwife enquiry

Down Syndrome - Physicians often fall short when delivering diagnosis, mothers report

Down Syndrome - Synaptic structural abnormalities identified in murine model

Drug Delivery - 6-Ketocholestanol improves skin permeation of 5-aminolevulinic acid

Drug Delivery - Characteristics of water-soluble phospholipid polymer hydrogels described

Drug Delivery - Glucose-targeted niosomes may deliver VIP to brain

Drug Delivery - Needle-free injection device made for use with insulin in India

Drug Delivery - Sweet basil essential oils enhance transdermal drug delivery

Drug Development -  Emblica officinalis extract reduces DMBA genotoxicity in mice

Drug Development - Animal study results point to ATL1102's potential as an inhaled asthma drug

Drug Development - AstraZeneca withdraws application to market lung cancer drug

Drug Development - Biophosphonates for bone metastases pain is potentially lucrative market

Drug Development - Cardiome's pivotal AF study achieves primary endpoint

Drug Development - Chemical microarray identifies FVIIa-binding compounds

Drug Development - Companies enter partnership to commercialize functional human protein arrays

Drug Development - Company launches the HCS Reader 2004 Upgrade

Drug Development - Company provides EVOscreen to Institut Pasteur Korea

Drug Development - EU expands approval of Advate for use in children with hemophilia A

Drug Development - Effects of novel anxiolytic AF-5 on monoamine neurotransmitters determined

Drug Development - Executives meet in Baltimore to discuss region's biotechnology growth

Drug Development - FDA grants approval for Enjuvia for vasomotor symptoms

Drug Development - First patient enrolled into phase II trial of Phenoptin for PKU

Drug Development - Genetic modifications increase antibiotic yields from microbes

Drug Development - Genetically engineered animals in drug development reviewed

Drug Development - Innovative R&D strategies are key to developing new drugs, according to study

Drug Development - Investigational new drug application submitted for cancer candidate

Drug Development - Ion exchange membranes capture vector-borne virus

Drug Development - Medicinal and pharmaceutical uses of seaweed natural products reviewed

Drug Development - Meeting with U.S. FDA completed for amoxicillin Pulsys phase III trial

Drug Development - Molecular diversity management schemes for compound screening outlined

Drug Development - NDA for Retaane submitted to U.S., European regulatory authorities

Drug Development - Novel centrally acting thyrotropin-releasing hormone analogues designed

Drug Development - Novel docetaxel analogues with high tubulin activity synthesized

Drug Development - Optimized freeze-drying keeps nonviral vectors stable during storage

Drug Development - Pharma company licenses Ingenuity Pathways Analysis application

Drug Development - Pharmaceutical company announces collaboration plans on NRP104

Drug Development - Pharmaceuticals company presents data on potency of antifungal, antibiotic drugs

Drug Development - Pharmacokinetics, safety, and tolerability of Oritavancin analyzed

Drug Development - Reactivation of beta-galactosidase by glutathione is tunable

Drug Development - Results reported from phase III study of alvimopan for postoperative ileus

Drug Development - Third performance milestone in Genentech Alliance announced

Drug Fatalities - Prescription drug deaths skyrocket in Virginia's coal region

Drug Importation - Canada considering ban of Internet pharmacy prescription drug trade

Drug Importation - Savings from purchasing drugs from Canada fell last year

Drug Importation - Trade group speaks out on drug supply chain safety

Drug Importation - Two governors complain to President Bush about Canadian drugs

Drug Research - Prospective allometric scaling is suboptimal for estimating clearance

Drug Resistance - ABC transporters have multiple functions in drug resistance

Drug Resistance - CDC issues public reminder about proper antibiotic use

Drug Resistance - Curcumin I most effective multidrug resistance modulator among curcuminoids

Drug Resistance - Genetic resistance to nevirapine emerging in pregnant HIV+ women

Earth Science - Outer layers of Earth contain solids heavily irradiated by solar ions

Eating Disorders - Core beliefs of eating disordered patients with anxiety need to be identified

Eating Disorders - Endorphin self-addictive model may apply to eating disorders

Eating Disorders - New data illuminates research in eating disorders

Electronic Medical Records - Companies compete in Medical Record Institute's ePrescribing challenge

Electronic Medical Records - Medical database provider upgrades to meet JCAHO patient safety compliance goals

Electrophoresis - Novel PDMS microchip has improved heat dissipation

Embryonal Brain Tumor - Notch1 and Notch2 can have opposite effects on single tumor type growth

Embryonic Stem Cell Research - Cryopreservation technique increases ESC viability and reduces differentiation

Embryonic Stem Cell Research - ESC gene profiles show more highly expressed genes than adult cells

Emergency Contraception - Study: Readily available EC doesn't increase unprotected intercourse, STI risk

Emergency Contraception - U.S. ob/gyn group: Study findings put spotlight on controversial FDA OTC ruling

Emergency Medicine - Insulin treatment in critically ill trauma patients normalizes glucose

Endocarditis - Elevated troponin I may be a reflection of myocardial involvement

Endocrinology - Activation of nuclear factor by hyperglycemia regulated by aldose reductase

Endocrinology - Affect of exogenous progestagens on the human breast remains controversial

Endocrinology - Cofilin suppresses glucocorticoid receptor activity in hormone-resistant cells

Endocrinology - Diabetes in pregnancy appears to imprint glucocorticoid regulation in fetus

Endocrinology - Expression of mini-proinsulin in Pichia pastoris improved

Endocrinology - GnRHA, TGF-beta influence fibronectin expression in endometrial cells

Endocrinology - Growth hormone prompts endocrine or paracrine activity during spermatogenesis

Endocrinology - Insulin acts via protein kinase phosphorylation in blastocysts

Endocrinology - Link found between mitochondrial efficiency and insulin resistance

Endocrinology - Microenvironmental factors guide glucocorticoid influence in the thymus

Endocrinology - Novel microbead system facilitates isolation of specialized cell types

Endocrinology - Scientists identified role of genes in corpus cardiacum morphogenesis

Endocrinology - Sesame lignans augment vitamin E activity in lipid peroxidation systems

Endocrinology - Specific hormone and growth factor mediated activation revealed

Endoplasmic Reticulum - Varied activation of endoplasmic reticulum stress-responsive elements revealed

Environmental Health - Cleveland, Ohio, combats childhood lead poisoning

Environmental Health - Component of plastic stimulates growth of certain prostate cancer cells

Environmental Health - People exposed to asbestos show early signs of autoimmunity

Environmental Health - Secondhand smoke linked to cognitive declines in children

Environmental Health - Synthetic musks may enhance the effects of toxic compounds

Environmental Health - U.S. NIST/EPA study aims at healthy indoor climate

Environmental Health - Validity of a food-frequency questionnaire reported and verified

Environmental Health - Waste minimization plans affect U.S. medical waste management

Enzymology - Aldoxime dehydratase studied, residues needed in triple bond synthesis revealed

Enzymology - Cyclooxygenase-2 studied, expression in H4 human neuroglioma cells revealed

Enzymology - Expression level of GGPS is regulated through splicing of intron 4b

Enzymology - Matrix metalloproteinases govern capillary tube formation differentially

Enzymology - Metal ions direct prostasin activity

Enzymology - Researchers' work adds to enzymology body of knowledge

Enzymology - Residues in factor Xa critical to interaction with Na+, factor Va

Enzymology - Sp1 mediates lysozyme activation in epithelial cells

Enzymology - Two-step activation manages gene expression in skeletal muscles

Epidemiology - Hepatitis E virus common among pregnant women in small study from India

Epidemiology - Molecular studies predict higher rates of liver cancer in the United States

Epidemiology - Results of HIV prevalence survey among general population in Niger released

Epidermal Growth Factor - Esophageal keratinocyte migration studied, role of signaling pathway revealed

Epilepsy - Chronic epilepsy decreases brain cell production in critical learning center

Epilepsy - Clonazepam may use alternate control routes in genetic absence epilepsy rats

Epilepsy - New clues to the genetics of epilepsy

Erythropoiesis - CPEC induces erythroid differentiation through CTP depletion and p38 MAP kinase

Escherichia Coli -  E. coli metabolism studied, role of transcription factor revealed

Escherichia Coli - Ozone treatment alternative to pasteurization

Escherichia coli - High incidence of ESBLs among outpatient clinical E. coli isolates

Esophageal Variceal Bleeding - FDA issues approvable letter for Sanvar for esophageal variceal bleeding

Estrogen - Estradiol-induced induction does not require direct MAPK/ERK activation

Ethics - NIH whistleblower says government bungled AIDS study in Uganda

Ethics - Study describes physicians' response to religious conflicts in medicine

Evolutionary Biology - Great tits show how differences can flourish

Evolutionary Biology - Holes in fossil shells show effects of competition and evolution

Fetal Medicine - New system may help babies avoid brain damage

Finance - ASP closes private placement

Finance - Agriculture produces company announces dividend

Finance - Antibody-focused biopharmeceutical company reports Q03 2004 financial results

Finance - Baby products manufacturer announces financial results

Finance - Biopharma focused on oral drug delivery secures $20M equity commitment

Finance - Biotech firm increases financing to $12,570,000

Finance - Biotherapeutic company announces financial results

Finance - Cancer-focused biopharmaceutical company files registration for proposed IPO

Finance - Cancer/inflammation-focused biopharma announces $14M private placement

Finance - Cell-based company executive adopts Rule 10b5-1 prearranged stock sales plan

Finance - China-focused company revises guidance, issues preliminary Q3 results

Finance - Clinical research organization reports second quarter financial results

Finance - Commercial health benefits company announces pricing for tender offers

Finance - Company announces closing of $60M private placement of common stock

Finance - Company's stock delisted, per its demand, from Berlin-Bremen stock exchange

Finance - Cryosurgical technology company closes second-round investment

Finance - DCI parent reports Q2 sales of approximately $3,172,000

Finance - DNA-focused company announces third quarter 2004 financial results

Finance - Dental Select buys out stock of shareholder

Finance - Device company closes $2.735M private placement

Finance - Device firm reports second quarter EPS up 50% to $0.09

Finance - Device maker to restate some historical financial statements

Finance - Diagnostics company reports loss of $0.12 per share

Finance - Drug development company raised third round of financing

Finance - Drug discovery company announced private placement

Finance - Emisphere agrees to new terms for note repayment

Finance - Female condom company reports Q4 2004 results

Finance - Food safety company announces financial results

Finance - Four teams awarded inaugural translational cancer research grants

Finance - Funding available to build behavioral health service system

Finance - Games for Health project receives major funding

Finance - Genetics-focused biopharmaceutical company reports Q3 2004 financial results

Finance - Health Care REIT, Inc., announces gross investments of $584.9M for 2004

Finance - Health care venture capital investments increase 23% in 2004, publisher reports

Finance - Health discount company announces stock transfer

Finance - Health management company pays to save

Finance - HearUSA reports 16% increase in December revenues

Finance - Hearing aid developer, manufacturer announces acceleration of option vesting

Finance - Hospice care provider expands credit facility to $50 million

Finance - Hospital company announces expected fourth quarter earnings shortfall

Finance - Imaging technology services provider reports third quarter 2004 results

Finance - InSightec parent announces completion of self-tender offer

Finance - Individual disability, group insurer files shelf registration statement

Finance - Laboratory files shelf registration statement

Finance - Medical device company announces record annual revenues, reports Q4 2004 results

Finance - Medical device company closes $26 million in financing

Finance - Medical device company closes Series B funding round

Finance - Medical imaging software company announces record revenue in third quarter 2004

Finance - Michigan insurer offers grants for community health projects

Finance - Michigan insurer provides grant to improve men's health

Finance - Nanotech company named to Merrill Lynch index

Finance - Nevada Cancer Institute gets $25 million "challenge grant"

Finance - Note exchange offer by hospital operator expires

Finance - Oncology-focused medical device company announces third quarter 2004 results

Finance - Online medical services provider reports third quarter 2004 results

Finance - Online secure medical services provider completes $20 million private placement

Finance - Owner of senior living facilities signs venture agreement with JPMorgan Fleming

Finance - Pharma announces pricing of $65M of 2.50% convertible subordinated debentures

Finance - Pharma company provides financial update

Finance - Pharmaceutical company announces results for fiscal 2005 first quarter

Finance - Pharmaceutical firm announces $12.5M private placement financing

Finance - Pharmaceutical firm closes $11.6M financing

Finance - Pharmaceutical firm reports loss of $0.09 per share

Finance - Pharmaceutical firm reports loss of $2.06 per share

Finance - Pharmaceutical firm sells $283M of senior convertible notes

Finance - Protein-focused biopharmaceutical company reports Q3 2004 financial results

Finance - Protein-misfolding-focused company closes on $16M round of funding

Finance - Regional Pennsylvania hospital association releases year-end financial report

Finance - Science-based growth company completes private bridge loan

Finance - Science-based pharmaceutical company reports third quarter 2004 financials

Finance - Secure healthcare information company begins trading under symbol SCUI

Finance - Service provider to morbidly obese patients reports third quarter 2004 results

Finance - South Broward Hospital District awards $50 million investment mandate

Finance - Technology company closes on $4.0 million private placement financing

Finance - Theranostics company closes private offering

Fitness & Wellness - Inflatable wedge holds door open for those looking to get in shape

Fitness & Wellness - Olympic gold medallist Kristine Lilly leads kids in action pilot program

Fitness and Wellness - British marathoner releases DVD and video on power walking off the pounds

Fitness and Wellness - Health club group predicts over 10 million Americans will join club in 2005

Fitness and Wellness - Minnesota yoga instructor's 'YogaLift' program wins 'Best of Fitness' honors

Food Contamination - F-specific coliphages detected by PCR in fresh market-ready produce

Food Safety - Emerging trends of foodborne illness surveillance and prevention analyzed

Food Safety - Food safety company's germicidal product passes U.S. EPA Protocal testing

Food Safety - Genome comparison of four Campylobacter strains yields genetic markers

Food Safety - Listeria food poisoning cases rose in '03

Food-Borne Disease - Lysozyme augments antimicrobial activity of chitosan films

Foot-and-Mouth Disease - Method to detect foot-and-mouth virus antibodies developed

Gallstone Disease - Eating nuts is associated with lower risk of gallstones in men

Gastric Bypass Surgery - Teen twins undergo controversial gastric bypass surgery

Gastric Cancer Diagnostics - LOH genotyping may be independent prognostic indicator in gastric carcinoma

Gastroenterology - Findings describe new data in gastroenterology research

Gastroenterology - Interferon-alpha and antisense K-ras RNA suppress pancreatic cancer cell growth

Gastroenterology - Synergy between acid and pepsin affects posterior laryngeal tissues

Gastroesophageal Reflux Disease - New method of measuring esophago-gastric junction competence developed

Gastrointestinal Stromal Tumor - Double-balloon enteroscopy aids in diagnosis of gastrointestinal stromal tumor

Gene Research - WDR25 gene is widely expressed in human tissues

Gene Silencing - Retroviral driven transfer of short hairpin RNA analyzes gene function

Gene Transfer - Jet injection and electroporation deliver plasmids to large muscles

Gene Transfer - Nucleotides targeting anti-apoptosis protein bind to erythroleukemia cells

Generic Drugs - Company announces the first approval of Ciclopirox Cream

Generic Drugs - Company launches Halobetasol Cream 0.05% (Rx), and Ointment 0.05% (Rx)

Generic Drugs - Pharma company receives approval for generic Accupril

Generic Drugs - Research: Generics provide consumers more savings than price controls

Generic Drugs - Spain to suspend reference-price system, support generics

Genetic Disorders - Dendritic cells made to express intereukin-12 prevent atopic disorders

Genomics - New research in the area of genomics detailed

Genomics - Varied recombination rates may bias gene mapping studies

Genomics and Genetics - ChIP assay used to identify glucocorticoid receptor target genes

Genomics and Genetics - Effects of tetrodotoxin exposure on human glial cells clarified

Genomics and Genetics - Gene expression in cochlea and kidney characterized

Genomics and Genetics - Growth arrest pathway genes also regulate metabolism and mitochondria

Genomics and Genetics - Novel statistical system improves study of gene coexpression dynamics

Genomics and Genetics - PCR use assessed in high surface-to-volume ratio SiO2 microstructures

Genomics and Genetics - Robust toolkit developed for functional profiling of yeast genome

Geriatrics - Aging-focused pharmaceutical company opens new research labs in North Carolina

Geriatrics - Data: Florida nursing home residents receive higher quality of care than in 2002

Geriatrics - Psychosocial intervention aids patients with age-related macular degeneration

Geriatrics - Rhode Island proposes nursing home reform

Geriatrics - Study of diuretics in elderly people says the benefits outweigh the risks

Gestational Diabetes - Oxidative stress involved in pathogenesis of gestational diabetes

Glioma - Diffusion-weighted imaging values highlight brain tumor invasion

Glioma - IFNgamma's inhibitory effect on COX-2 expression relevant to glioma therapy?

Global Health - International commission would coordinate global relief efforts

Global Health - Science should be at center of decision making for developing nations

Gonadotropins - Gonadotropin subunit structure studied, role of disulfide bridges revealed

Graft-Versus-Tumor Effect - Graft-versus-tumor effect following ASCT generated against solid tumors

Grants - Nevada Cancer institute receives $25 million matching-funds grant

Grants - Univ. of Oklahoma Health Center sees grant increases

Group B Streptococcal Infection - Effects of intrapartum penicillin prophylaxis studied in infants

Gynecologic Surgery - Women need less morphine after hysterectomies with new treatment

Gynecology - Company reports 2005 Medicare payment value for cryoablation therapy

Gynecology - Doppler flow studies don't differentiate leiomyomas from leiomyosarcomas

Gynecology - SU5416 controls enzyme signals to block ovarian cancer angiogenesis

Gynecology - Transcriptional switches initiate estrogen-regulated endometrial growth

HIV/AIDS Epidemiology - Surveillance needed to track epidemiology of HIV among Mexican migrants in US

HIV/AIDS Healthcare - Education positively associated with awareness of HIV/AIDS-related services

HIV/AIDS Healthcare - Point-of-care rapid HIV testing may improve entry into healthcare

HIV/AIDS Prevention - Acceptability of HIV prevention strategies in central Tanzania explored

HIV/AIDS Prevention - Comprehensive response to HIV could prevent 10 million AIDS deaths in Africa

HIV/AIDS Prevention - German pharmaceutical company continues commitment to HIV/AIDS community

HIV/AIDS Prevention - Indian media to boost government efforts in combating AIDS

HIV/AIDS Prevention - Misconceptions about medical advances may lead to risky sex practice

HIV/AIDS Prevention - Multifaceted intervention strategy associated with lower HIV rates

HIV/AIDS Prevention - One in five HIV-positive men knowingly put sexual partners at risk

HIV/AIDS Prevention - Policy policies analyzed that affect HIV prevention in Mexican migrants

HIV/AIDS Prevention - U.S. NIH overlooked problems in Uganda AIDS study, whistleblower says

HIV/AIDS Research - Anti-termination by SIV Tat requires flexibility of nascent TAR structure

HIV/AIDS Research - HIV-1 Vpr-mediated G(2) arrest requires Rad17 and Hus1

HIV/AIDS Research - Reports add new data to HIV/AIDS research

HIV/AIDS Research - Researchers publish new studies and findings in the area of HIV/AIDS

HIV/AIDS Risk - Scientists discover key genetic factor in susceptibility to HIV/AIDS

HIV/AIDS Therapy - AIDS Drug Assistance Program of Utah selects prescription benefit service

HIV/AIDS Therapy - Acute interstitial nephritis associated with protease inhibitor atazanavir

HIV/AIDS Therapy - Clinical cutoffs for TYPE HIV-1 resistance test established

HIV/AIDS Therapy - Deferring HAART initiation until CD4 cells drop below 200mm3 is detrimental

HIV/AIDS Therapy - NNRTI capravirine reduces HIV-1 viral load in phase 1 study

HIV/AIDS Therapy - New therapeutic vaccine for HIV/AIDS eliminates needles and excessive toxicity

HIV/AIDS Therapy - Reports advance knowledge in HIV/AIDS therapy research

HIV/AIDS Therapy - Researchers describe findings in HIV/AIDS therapy studies

HIV/AIDS-Associated Infection - Saquinavir & miconazole synergistic against C. albicans & C. neoformans

HIV/AIDS-Related Disease - Tumid lupus erythematosus uncovered following HAART-related immune restoration

HIV/AIDS-Related Nutrition - Vitamins C and E protect against AZT-induced oxidative stress

Haemophilus Influenzae - Study shows higher incidence of H. influenzae type b than previously known

Hair Studies - Forkhead gene Foxe1 required for hair follicle morphogenesis

Health Education - Cancer support talk radio show now heard via Internet and satellite

Health Education - U.S. young people's views of sexual terms undergo big changes

Health Promotion - Blue Shield of California pays members for healthy behavior

Health Promotion - Cigna behavioral health doubles online coaching program

Health Promotion - Kids dental program named one of five national models

Health Promotion - Medicare will help beneficiaries quit smoking

Health Promotion - Minnesota partnership for smoking cessation offers QUITPLAN services

Health Promotion - National Parent Leadership month to be observed in February

Health Promotion - Online resource for expectant parents helps pregnant women to quit smoking

Health Promotion - Prevention organization comments on Medicare coverage of smoking cessation

Health Promotion - Programs support employee wellness

Health Promotion - VoiceAmerica Network airs "The Gary Null Show"

Health and Politics - Post-apartheid cultural politics of HIV/AIDS in South Africa analyzed

Healthcare Access - Alaska clinics hope to improve patient satisfaction and cut no-shows

Healthcare Access - Barriers to infectious disease care among lesbians identified

Healthcare Access - Cherokee Nation to build Muskogee clinic in Oklahoma

Healthcare Access - Coalition reaches consensus on priorities for improving healthcare quality

Healthcare Access - Healthy Finds helps Americans make educated decisions about health care

Healthcare Access - New burn center celebrated at biosciences conference

Healthcare Access - PA Governor announces agreement on nursing home assessment

Healthcare Costs - Americans have variety of domestic options for savings on drugs

Healthcare Costs - California health insurance premiums continue double-digit increases

Healthcare Costs - Regulators approve rate increase for Parkersburg, West Virginia, hospital

Healthcare Costs - Report shows Wisconsin school districts could save with health insurance plan

Healthcare Costs - West Virginia faces mental health care crisis

Healthcare Coverage - AHIP launches unique online resource on health savings accounts

Healthcare Coverage - Arkansas Governor discusses healthcare

Healthcare Coverage - California leader calls for more taxes to protect schools, healthcare

Healthcare Coverage - Drug store chain stops accepting Ohio state employee prescriptions under plan

Healthcare Coverage - Financial corporation enters agreement to provide health savings plans

Healthcare Coverage - GI societies call for insurance coverage for colorectal cancer screening

Healthcare Coverage - Gevity announces 2005 workers' compensation program

Healthcare Coverage - Humana adds Newport Beach hospital to its ChoiceCare Network

Healthcare Coverage - Humana adds out-of-pocket cost data as a consumer-focused enhancement

Healthcare Coverage - Insurance company announces new product for health care providers

Healthcare Coverage - Lawmakers look to help needy children, adults receive healthcare

Healthcare Coverage - New DirigoChoice enrollees tout state health plan in Maine

Healthcare Coverage - Pharmacy group offers tips to boost pharmacy drug benefits lingo

Healthcare Coverage - Program launched to help uninsured with sleep disorders

Healthcare Coverage - Simply Secure healthcare savings program to launch first quarter 2005

Healthcare Coverage - U.S. HHS issues final regulation on access to group health coverage

Healthcare Coverage - Unions bargain away healthcare for same-sex partners in New York town

Healthcare Coverage - World leaders vow to work together to help tsunami victims

Heart Disease Mortality - Depression tied to higher risk of heart disease death

Heart Disease Risk Factors - Adiponectin reduced in acromegaly and normalized by growth hormone correction

Heart Disease Risk Factors - Endothelial dysfunction in women with PCOS related to insulin resistance

Heart Failure - Nursing professor wins prize for arteriosclerosis , heart failure report

Heart Surgery - Study: Mortality risk doesn't differ between sexes after PCI

Heart Surgery - Transesophageal echocardiography unreliable for cardiac output assessment

Heat Shock Proteins - Structure of small heat shock proteins changed in response to pH

Heathcare Costs - Missouri sees $7.7 Million in mental health services savings

Helicobacter pylori -  Helicobacter pylori may play role in conjunctival MALT lymphoma

Hematology - Novel assay enables simultaneous analysis of specific platelet antibodies

Hematology - Novel ligand display technology transduces hematopoietic cells

Hematology - PECAM-1 mediates platelet aggregation on irradiated endothelial cells

Hematology - Prenatal gene therapy corrects hemophilia B in immunocompetent mice

Hematology - Proangiogenic protein protects multiple myeloma from apoptosis

Hematology - Tests detect occult hepatitis B in North American hemodialysis patients

Hematopoiesis - Follistatin and follistatin-related gene have distinct hematopoietic functions

Hematopoietic Malignancy - Blocking constitutive STAT5 activation may treat hematopoietic malignancies

Hemoglobinuria -  Clostridium septicum mutants used to diagnose hemoglobinuria

Hepatitis B Therapy - Peg-IF monotherapy effective in over one-third of patients

Hepatitis B Virus - Thymalfasin has the potential to treat patients with chronic hepatitis B

Hepatitis C Therapy - Company reports results from phase Ia/Ib studies of Actilon for hepatitis C

Hepatitis C Virus - A HCV IRES-mediated translation initiation model clarifies domain function

Hepatitis C Virus - Ampligen clinical program initiated in HIV patients with or without HCV

Hepatitis C Virus - CD4+CD25+ regulatory T lymphocytes encourage hepatitis C virus persistence

Hepatitis C Virus - Man infected with hepatitis C during test dies

Hepatitis C Virus - Positive results from study of oral protease inhibitor for hepatitis C reported

Hepatitis C Virus - Testing for hepatitis C should be routine for persons at increased risk

Hepatitis C Virus - Vial from Cardinal Health pharmacy part of hepatitis probe

Hepatitis Therapy - DHEA reduces hepatic inflammation in hepatitis models

Hepatoblastoma - Single-agent cyclophosphamide ineffectual in refractory, relapsing HB patients

Hepatocellular Carcinoma - Risk of delirium after liver resection for hepatocellular carcinoma studied

Hepatocytes - Some gene activities in hepatocytes do not require growth factor receptor

Hereditary Antithrombin Deficiency - Company provides ATryn program update

Herpes Risk Factors - Study finds herpes virus in 98% of healthy participants

Herpes Simplex Virus - Herpes simplex virus studied, activity of alpha-helical peptides revealed

Hormone Replacement Therapy - Adding methyltestosterone to esterified estrogen improves lipoprotein profile

Hormone Replacement Therapy - Overall risk of developing hypertension during HRT is low

Hormone Replacement Therapy - Review supports link between HRT and stroke

Human Genome - Laboratory devises technique to explain patterns of gene regulation

Human Papillomavirus - CDK inhibitor inhibits HPV-16 E7-induced numerical centrosome anomalies

Human T Cell Leukemia Virus - HTLV-1 Tax ubiquitination modulates its activity

Human T-Cell Leukemia Virus - Stable ubiquitination of HTLV-1 tax required for proteasome binding

Hyperglycemia - VEGF and high glucose levels mediate placenta growth factor activity

Hypertension - Calcium channel blockers boost women's risk of CVD death than other treatments

Hypertension - DETA/NO has potent blood pressure lowering effects

Hypertension - Gene mapping supports a relationship between the Add1 gene and blood pressure

Hypertension - Genes don't explain higher blood pressures among African Americans

Hypertension - New findings in the area of hypertension described

Hypertension - New findings in the area of hypertension detailed

Hypertension - Sodium intake influences vasoconstriction in cold-induced hypertensive rats

Hypertension - TDI analysis could detect precocious LV global diastolic dysfunction

Hypertension - Transfer function to calculate aortic from upper limb pressure validated

Hypodermoclysis - Vitrase launches in the United States

Hypogonadism - Companies announce approval of Tostrex gel in first European country

Hypothyroidism - Adjusting pre-conception L-T4 dose may yield adequate maternal thyroid function

Imaging - Gonad capsule effective method for blocking radiation to testes from scan

Imaging - Knowledge of ECG artifacts during high-field MRI is essential

Imaging - LV strain is not uniformly distributed over the wall

Imaging - MRI deconstructs brain's complex network

Imaging - MRI technique is integrated for deformation field reconstruction

Imaging - Method accurately segments vessels from MRA data

Imaging - Study determines commonly used contrast agent safe for "universal use" in CT

Imaging - Technique provides detailed tomographic images of the inner organs

Immunology - Active subgroup of small intestinal intraepithelial lymphocytes identified

Immunology - Beta-casein (1-28) exerts mitogenic effect on T and B lymphocytes

Immunology - Drm/Gremlin and Dan interact with Slits and inhibit monocyte chemotaxis

Immunology - Researchers provide details of new studies and findings in the area of immunology

Immunology - Researchers report details of new studies and findings in the area of immunology

Immunology - Studies add new findings to immunology body of knowledge

Immunology - Studies advance knowledge in immunology research

Immunosuppression - Leflunomide protects the liver from T-cell-mediated injury

Infant Mortality - Cuba says its infant mortality rate for 2004 was lowest in Latin America

Infection - Inhibition of human and Leishmania donovani topoisomerases revealed

Infections - Growth of Escherichia coli O157:H7 inhibited in vitro by colicin

Infectious Disease - Poly(ADP-ribose) polymerase-1 inhibition disrupts the chlamydial life cycle

Inflammatory Bowel Disease - Coinfection with CMV frequent in IBD patients on immunosuppressive therapy

Influenza - Flu activity picking up in Colorado; vaccine restrictions lifted

Influenza Vaccine - Alabama health officials expand list of people who can get flu shots

Influenza Vaccine - Flu vaccine to be more widely available in New Mexico

Influenza Vaccine - Missouri relaxes guidelines for flu vaccine

Influenza Vaccine - More adult flu vaccine available in Florida

Influenza Vaccine - New Jersey eases restrictions on influenza vaccine

Influenza Vaccine - New York relaxes flu shot restrictions

Information Technology - American TeleCare selected to participate in VA's telehealth program

Information Technology - Cameras and computers enable U.S. doctors to watch over patients from afar

Information Technology - Caritas Christi Health Care's network deploys security platform

Information Technology - Clinical information software provider announces go-live at Mississippi hospital

Information Technology - Company awards $4.6 million for studies of cardiac safety monitoring services

Information Technology - Company launches consultancy to provide healthcare-related wireless service

Information Technology - Electronic medical records company ranked lead provider by IT advisory service

Information Technology - Florida insurer upgrades online resource for uninsured Floridians

Information Technology - Georgia Chiropractic Association chooses payment processing system

Information Technology - Health information company launches enhanced health news channel

Information Technology - InFORM Radiology Information System to add billing function

Information Technology - Internet-based company launches life sciences information channel

Information Technology - Medical web site to provide health-related content on Earthlink start page

Information Technology - Pharma firm adopts MDL Isentris platform to boost R&D

Information Technology - Rhode Island hospital implements emergency department information system

Information Technology - Software company launches new practice management system

Information Technology - Software delivers real-time electronic device history record solution

Information Technology - Technology company launches data collection software

Information Technology - Technology company to install IT infrastructure for Wockhardt Pharmaceuticals

Information Technology - University health system selects communications protection software suite

Information Technology - Updated commerce-optimization software released

Information Technology - Voluntary health organizations, publishers announce information initiative

Information Technology - Wireless healthcare making money for technology companies, report analyst says

Injury Prevention - Children at risk from unexploded military material

Injury Prevention - Injury toll in U.S. homes tops 12 million yearly

Injury Prevention - Most alcohol-related plane crashes occur at night, in bad weather

Injury Prevention - Parents more likely to follow advice if they trust their children's doctors

Injury Prevention - Snowy roads lead to more crashes

Insemination -  Apis mellifera insemination can produce different sperm survival

Interstitial Cystitis - IC is more prevalent in managed care population than previously thought

Irritable Bowel Syndrome - Study of pro-motility agent shows improved work productivity in women with IBS

Ischemia - Neuroprotection analyzed, role of fructose-1,6-bisphosphate revealed

Ischemia - Reports describe recent advances in ischemia research

Ischemia - Researchers' findings advance ischemia research

Ischemia/Reperfusion - Studies describe new findings in ischemia/reperfusion research

Kaposi Sarcoma-Associated Herpes Virus - Small GTPase Rac1 links KSHV vGPCR to cytokine secretion and paracrine neoplasia

Kaposi Sarcoma-Associated Herpesvirus - Fetal mesencyhmal stem cells susceptible to KSHV infection

Kaposi Sarcoma-Associated Herpesvirus - Findings describe new data in kaposi sarcoma-associated herpesvirus research

Kearns-Sayre Syndrome - Deleted mitochondrial DNAs reduced by ketogenic treatment

Kidney Disease - Altered podocyte-derived VEGF assembly may precipitate diabetic glomerulopathy

Kidney Infection - Sexual behavior, genetic factors increase risk in women under 50

Knee Replacement - Factors determining wear in Press-Fit Condylar modular system identified

Knee Replacement - Mini-midvastus approach improves TKA outcome

Knee Replacement - Risks of bilateral total knee replacement elucidated

Knee Replacement - Two-stage reimplantation of infected TKA has high long-term success rate

Lab Technology - Brand perceptions of scientific instrumentation suppliers established

Lactation - Breast milk samples from different donors contain similar oligonucleotides

Language - Spanish whistles get brain's language center ticking

Lead Poisoning - Low levels of lead affect proliferation and differentiation of embryonic NSCs

Legal Issues - Augsburg flu shot case referred to federal prosecutors

Legal Issues - Hypnotist reaches plea deal over charges of sex with patients

Legal Issues - Indiana seeks probation for nursing home

Legal Issues - Jury finds for Utah women in diet drug fen-phen verdict with $2.1 million award

Legal Issues - Lilly denies report of missing Prozac documents

Legal Issues - New health law sometimes poses problem for police

Legal Issues - Newspaper reviews human services system privatization

Legal Issues - Payments settle allegations over free vaccines

Legal Issues - Pfizer sued over painkiller

Legal Issues - Settlement reached in brain harvesting lawsuit

Legal Issues - South Carolina hospitals join to fight lawsuits

Legal Issues - Special prosecutor appointed in brain harvest probe

Legal Issues - U.S. Attorney reports guilty plea in kick-back case

Legal Issues - U.S. court upholds patent infringement suit against generic antibiotic maker

Legionella pneumophila -  Legionella pneumophila genomes have high plasticity

Leishmania Diagnostics - Real-time RT-PCR and PCR-ELISA quantifies L. infantum from tissue biopsies

Leishmaniasis - Drug company receives regulatory approval in Germany for leishmaniasis therapy

Leishmaniasis - New findings in the area of leishmaniasis described

Leptin Studies - Leptin levels are dependent on sleep duration

Lesch-Nyhan Disease - Novel mutations involved in HPRT deficiency identified

Leukemia - Chemotherapy drug combination shows promise for leukemia treatment

Leukemia - Girl in remission after leukemia diagnosis, twin sister's organ donation

Leukemia - Higher BMI associated with increased risk of AML, but not CLL in older women

Leukemia - Isolated extramedullary relapse appears common after Chemo-DLI

Lipid Studies - Hazelnut oil reduces aortic cholesterol accumulation

Lipid Studies - Novel FA2H gene encodes a fatty acid 2-hydroxylase

Lipoprotein - Lipoprotein related enzymes studied, role of high density lipoprotein revealed

Liposomal Delivery - Production of TGF-beta studied, role of a kinase and liposomes revealed

Listeria - Epidemic L. monocytogenes dairy farm strain causes sporadic human illness

Liver Cancer - Genes with prognostic value in hepatocellular carcinoma identified

Liver Cancer - Quercetin induces selective growth inhibition/apoptosis in hepatic tumor cells

Liver Cirrhosis - Neuropsychiatric test developed for subclinical hepatic encephalopathy

Liver Disease - Action plan released addressing burden of liver disease

Liver Disease - CYP2E1 inhibitors oppose liver injury

Liver Disease - NIH action plan charts future challenges for research

Liver Disease - Nuclear import of proinflammatory transcription factor fuels liver cell death

Liver Fibrosis - A dual reporter gene transgenic mouse aids hepatic fibrogenic investigation

Liver Fibrosis - Antioxidant boosters staunch fibrosis in rodent livers

Low Back Pain - Tool identifies low back pain patients who will benefit from spinal manipulation

Lung Cancer - PI3-kinase pathway involved in early progression

Lung Research - Technique allows lung-specific delivery of reagents

Lung Transplant - Living-related lobar lung transplants may increase donor availability

Lysosomal Storage Disease - Alpha-N-acetylglucosaminidase replacement treats Sanfilippo syndrome models

Lysozyme - Lysozyme activity analyzed, effects of Ni2+ revealed

Lysteria monocytogenes -  L. monocytogenes attachment to alfalfa sprouts leads to irrigation changes

Machado-Joseph Disease - Cell death plays a role in the pathogenesis of Machado-Joseph disease

Macular Degeneration - Study shows drug effectively treats neovascular age-related macular degeneration

Malaria - Travelers to Dominican Republic should take prophylaxis

Male Infertility - Sperm-sorting machine electronically filters healthy sperm for IVF

Malignant Mesothelioma - MM cells expressing Slug have increased resistance to chemotherapeutic agents

Market Analysis - What is driving the rise in over-the-counter drugs?

Mastitis - Calcium inhibits bap-dependent multicellular behavior in Staphylococcus

Medical Device - Opsonization of wear particles regulates macrophage responses

Medical Device - Robotic pyeloplasty reviewed

Medical Device Reimbursement - ExacTrac X-Ray 6D technology now eligible for reimbursement

Medical Devices - Capture detection in cardiac pacing reviewed

Medical Devices - Counterpulsation algorithm devised for moving-actuator type pulsatile LVAD

Medical Devices - Dynamic characteristics of VentrAssist implantable rotary blood pump determined

Medical Devices - Highly integrated sphincter prosthesis developed

Medical Devices - Internet-based home care monitoring system developed

Medical Devices - Medical device company gets IDE for embolic protection filters in clinical trial

Medical Devices - Optimum placement of ports in robotic urinary tract surgery outlined

Medical Devices - Valve-specific parameters for mechanical heart valve cavitation determined

Medical Errors - Deadly drug mistakes spike at the start of each month

Medical Errors - New medication management products, consulting services launched

Medical Errors - Robot mixes medications, prepares syringes

Medical Errors - Surgeon who left patient on operating table to pay $1.25 million settlement

Medical Imaging - First magnetic resonance imaging applications lab to be built in Oxford, U.K.

Medical Imaging - Flat detectors increasingly replacing x-ray film, company reports

Medical Imaging - IT company awarded 3-year medical center contract for digital imaging services

Medical Imaging - Ultrasound systems company introduces zone sonography ultrasound platform

Medical Malpractice - Group of doctors says medical reform bill should become law

Medical Malpractice - U.S. President pushes for lawsuit limits in county dubbed 'judicial hellhole'

Medicare - Company's managed care coverage for Medicare beneficiaries expanded by U.S. CMS

Melanoma - Order of treatment critical for avoiding toxicity

Meningiomas - Galectin-3-binding sites, S100B may affect atypical meningioma aggressiveness

Menopause - Anti-mullerian hormone is promising predictor of menopausal transition.

Mental Health - Effects of lithium on neuronal growth cone behavior determined

Mental Health - Effects of oral hormone receptor antagonist studied in a primate stress paradigm

Mental Health - Hundreds of disaster survivors seek counseling

Mental Health - Money issues leading cause of holiday stress for Americans

Mental Health - New treatment for depression approved in Europe

Mental Health - Quetiapine elevates noradrenaline and dopamine release in rat prefrontal cortex

Mental Health - Rgs2 is a quantitative trait gene for anxiety in mice

Mergers & Acquisitions - A4 Health Systems acquires Canopy Systems

Mergers & Acquisitions - AXIA Health Management launched, merges with HealthCare Dimensions

Mergers & Acquisitions - American Red Cross Transplantation Services tissue banking assets to be acquired

Mergers & Acquisitions - Biotech company puts merger plans with Panacos Pharmaceuticals on hold

Mergers & Acquisitions - California company acquires BestCare

Mergers & Acquisitions - Company acquires four dialysis facilities

Mergers & Acquisitions - DTLL, Inc., closes on acquisition

Mergers & Acquisitions - Definitive agreement to sell optical retail chain announced

Mergers & Acquisitions - Developers of Health Data Focus merge

Mergers & Acquisitions - Dragon extends share purchase agreement in connection with proposed acquisition

Mergers & Acquisitions - Ecolab acquires water-care company

Mergers & Acquisitions - Embryo Development Corp. discusses potential merger

Mergers & Acquisitions - Eye Care International acquires N-CAM

Mergers & Acquisitions - French contract research organization acquired

Mergers & Acquisitions - Health curriculum provider acquired by healthcare marketing firm

Mergers & Acquisitions - HealthCare Partners merges with Harriman Jones Medical Group

Mergers & Acquisitions - IMV Ltd. acquires AuntMinnie.com business

Mergers & Acquisitions - Independence Holding Company acquires Health Plan Administrators, Inc.

Mergers & Acquisitions - Institutional pharmacy provider acquires UniScripts, Inc.

Mergers & Acquisitions - Letter of intent issued to acquire Synova Healthcare

Mergers & Acquisitions - Medical device maker enters into agreement to acquire stent developer

Mergers & Acquisitions - Medical hand-held device company postpones acquisition of Israeli company

Mergers & Acquisitions - Medical transcription technology company acquires Avicis, formerly HealthScribe

Mergers & Acquisitions - Momentum Computer, Inc., acquired by computer company

Mergers & Acquisitions - Nanotechnology company merges with C Sixty

Mergers & Acquisitions - Oral care product development business acquired for EUR 8M

Mergers & Acquisitions - Pharma company to acquire ProBio International

Mergers & Acquisitions - Pharmaceutical company merger approved

Mergers & Acquisitions - Therapeutics company acquires interest in Alzheimer-focused Ellipsis

Mergers and Acquisitions - Medical closure system company to sell drug delivery business

Metabolic Syndrome - Growth hormone and placental lactogen genes linked to metabolic syndrome

Metabolic Syndrome - Hepatic lipase mRNA, protein, and enzymes increased in insulin resistance

Metabolic Syndrome - Research shows metabolic syndrome drug market to increase by 2013

Metabolic Syndrome - Studies add new findings to metabolic syndrome body of knowledge

Metabolic Syndrome - Weight, fitness and lifestyle important contributors to metabolic syndrome

Metabolic Syndrome - von Willebrand factor does not predict development of metabolic syndrome

Metabolism - Energy expenditure in elderly investigated

Metalloproteins - Alpha-helical coiled coil peptide that binds Ni(II) and Cu(II) designed

Metastases - Scientists study how cancer cells get out of control

Metastatic Melanoma - Taxanes may be treatment option for metastatic melanoma

Microbiology - Involvement of linear plasmids in aerobic biodegradation of vinyl chloride

Migraine - Handout focuses on menstrual migraine

Molecular Biology - Protein transformation gives new twist to medical research

Molecular Biology - Research-products provider introduces pre-poured Agar plates for bacteria growth

Molecular Biology - Researchers report on carbohydrate-carbohydrate interactions in cell recognition

Molecular Biology - tRNA global structure varies more than had been supposed

Molecular Diagnostics - Multiplexed RT-PCR valuable for high throughput screening applications

Monoclonal Antibody - Analysis of myeloma cell lines for antibody production conducted

Monoclonal Antibody - System to select cells producing glycosylated single-chain Fv developed

Movement - Exploring the brain's internal stopwatch

Mucosal Immunization - Research add new data to mucosal immunization body of knowledge

Multiple Myeloma - Cancer drug study results indicate potential for treating multiple myeloma

Multiple Sclerosis - Alpha lipoic acid has implications as a therapy for multiple sclerosis

Multiple Sclerosis - Software selected to support multiple sclerosis research partnership

Mutagenesis - Electrochemiluminescence assay shows point mutations in cancer samples

Mutagenesis - Researchers' data advance mutagenesis research

Mutagenesis - Topoisomerase inhibitors pursue chromatin to alter paternal chromosomes

Myelodysplastic Syndrome - MoDCs in MDS have abnormalities that contribute to defective immune response

Myocardia - PPARalpha may mediate mitochondrial response to thyroid hormone

Myocardial Infarction - AB5000 ventricle patient supported for more than 37 days

Myocardial Infarction - Cord blood cells limit heart attack damage in animal study

Myocardial Infarction - Normal LV wall motion does not exclude myocardial infarction

Myocardial Infarction - RV involvement in MI should be detected as early as possible

Myocardial Infarction - Working while ill boosts heart-attack risk

Myopathy - Gene mutations associated with congenital myopathies produce varying effects

Nanoparticles - Biomolecular interaction between biotin and streptavidin detected

Nanotechnology - Nanotechnology company introduces new product line

Nanotechnology - New protein holds promise for use in medicine and nanoscience

Nanotechnology - Research shows nanomaterials are establishing commercial presence in U.S.

Natural Medicine -  Phyllanthus amarus extract reduces HIV replication

Neoplasia - Bcl-2-related genes important in tumor initiation/progression/therapy response

Neovascularization - Ex vivo murine aorta cultures model angiogenesis

Neovascularization - Mast cell-derived angiopoietin-1 promotes plasmacytoma growth

Neurodegeneration - Beta-synuclein gene transfer protects mice from nervous system degeneration

Neurodegeneration - Geranylgeranylation inhibition mediates HMG-CoA reductase inhibitors

Neurodegeneration - New findings in neurodegeneration described

Neurodegenerative Disease - Cell-specific patterns of tau-dependent process formation identified

Neurodegenerative Disease - Protein stability unaffected by polyglutamine expansion in ataxin-3

Neurofibromatosis - Brain tumor study reveals why treatment efforts fail in genetic disorder

Neurology - Genetic and epigenetic events highlight the etiology of autism

Neurology - Inositol monophosphatase 2 expression is implicated in bipolar disorder

Neuroscience - Coding and decoding of spatial position by nervous system elucidated

Neuroscience - Effects of PVN spider venom on blood-brain barrier permeability clarified

Neuroscience - Effects of fluoxetine on locus coeruleus in early protein deprivation assessed

Neuroscience - Effects of microtubule-stabilizing agent Taxol in rat hippocampus characterized

Neuroscience - Estradiol uses a receptor-dependent mechanism to protect hippocampal neurons

Neuroscience - Hepatic glucose responses to electro-acupuncture characterized in rats

Neuroscience - Hepatocyte growth factor revitalizes memory function after cerebral ischemia

Neuroscience - Human alpha-synuclein impairs neurogenesis in mice

Neuroscience - Increasing attention has provided information about social phobia

Neuroscience - Ligation preconditioning protects the rodent brain from hypoxia-induced injury

Neuroscience - Mab35 immunoreactivity characterized in rat magnocellular neurons

Neuroscience - New findings in the area of neuroscience detailed

Neuroscience - New research in the area of neuroscience detailed

Neuroscience - Novel ALS2-derived somatodendritic marker for neurons identified

Neuroscience - Novel assay ATP release in molluscan central nervous system

Neuroscience - Online microdialysis-CE system used to monitor rat D-serine dynamics

Neuroscience - Recent findings in neuroscience described

Neuroscience - Recent findings in neuroscience provide new insights

Neuroscience - Representation of sound intensity in rat auditory cortex characterized

Neuroscience - Researchers detail new studies and findings in the area of neuroscience

Neuroscience - The Wilms tumor gene is overexpressed in primary astrocytic tumors

Neuroscience - Vitronectin regulates Ih current in mouse hippocampal neurons

Neutropenic Sepsis - Infusion of G-CSF may reduce duration, severity of neutropenia

Nitric Oxide - Endogenous NO modulates aldosterone synthesis in humans

Nitric Oxide - NO synthesis inhibition affects physiological response to mental stress

Nitric Oxide - Review explores the causes of nitric oxide insufficiency

Non-Hodgkin Lymphoma - Pesticide exposure may be associated with increased risk of NHL among women

Non-Small Cell Lung Cancer - Cancer vaccine trial data updated

Nosocomial Infections - Isolation of ICU patients with MRSA does not prevent cross-infection

Nutrition - Dynamic rheology of gelatine-sugar composites measured during aging

Nutrition - Infant formula quality studied, role of specific saccharide ratio revealed

Nutritional Supplements - Alliance calls for donation of children's vitamins for Asian tsumani victims

Obesity - Frequent fast food meals increase weight, diabetes risk

Obesity - Insufficient sleep associated with overweight and obesity

Obesity - Maker of handheld mobile devices introduces applications for weight management

Obesity Genomics and Genetics - Mutation in PPAR-gamma promoter linked to partial lipodystrophy

Obesity Pathogenesis - Brain region-specific forms of obesity linked to agouti expression

Obesity Pathogenesis - IL-6 regulates adipose tissue lipid metabolism and leptin production

Obesity Pathogenesis - New data illuminates research in obesity pathogenesis

Obesity Surgery - Gastric bypass successful in obese patient with myasthenia gravis

Obesity Surgery - Gastric outlet obstruction caused by total band erosion

Obesity Surgery - Silicone tube of gastric band causes small bowel

Obesity Therapy - Findings advance knowledge in obesity therapy research

Obesity and Diabetes - Age has independent effect on insulin sensitivity and beta-cell function

Obesity and Diabetes - Beta-cell function and insulin sensitivity associated with body fatness

Obesity and Diabetes - Ciliary neurotrophic factor decreases weight and improves metabolism

Obesity and Diabetes - Free fatty acid levels modulate microvascular function

Obesity and Diabetes - Intranasal insulin reduces body fat in men but not in women

Obesity and Diabetes - Mitochondrial remodeling in adipose tissue associated with obesity

Obesity and Diabetes - Phosphatidylinositol/AKT/atypical PKC pathway improves insulin sensitivity

Obesity and Diabetes - c-Cb-deficient mice have reduced adiposity and improved insulin action

Obstetric Anesthesia - General anesthesia used in about 20% of cesarean sections in Singapore hospital

Obstetric Anesthesia - U.S. medical center conducts retrospective analysis of anesthesia failures

Obstetric Nursing - "Kangaroo care" treats young woman's grief, anxiety, perinatal problems

Obstetrics - Birth simulator helps identify least forceful way to manage problem deliveries

Obstetrics - Cerebral hemodynamic changes present in women who develop preeclampsia

Obstetrics - Conditional month difference, imputed month midpoint better for timing events

Obstetrics - Higher dose of clomiphene doesn't appear to increase risk of poor outcome

Obstetrics - Intrauterine inflammation increases with prolonged latency after PPROM

Obstetrics - Nearly half of extremely premature babies have significant disabilities later

Obstetrics - New findings in obstetrics described

Obstetrics - Newer antidepressants don't appear to adversely effect pregnancy outcome

Obstetrics - University Hospitals examines screening of babies for drugs

Occupational Health - Welding fumes suppress lung defense responses after bacterial infection

Olfaction - Dopaminergic phenotype analyzed, olfactory differentiation revealed

Oncogenesis - Hepatitis C virus transfection produces liver cell growth and tumorigenesis

Oncogenesis - Research in oncogenesis provides new insights

Oncology - Chromosome changes are prognostic indicators in multiple myeloma patients

Oncology - Integrin signals link survival elements in recurrent prostate cancer

Oncology - Interleukin-10 may enable liver cancer to evade immune response mechanisms

Oncology - Paclitaxel halts angiogenesis at similar rates despite dissimilar scheduling

Oncology - Putative HOX11 target genes identified

Oncology - Researchers provide details of new studies and findings in the area of oncology

Oncology - SPRY2 activity in presence of wild-type and mutant BRAF clarified

Oncology - Studies advance knowledge in oncology research

Oncology - T cell type cancer predominates in Korean primary hepatic lymphoma cases

Oncology - Thrombin is involved in tumor invasion

Oncology - Ultrasonography accurately detects lymph-node invasion

Ophthalmology - Educating employees about eye safety can protect their vision

Oral Cancer - Dietary zinc affects cox-2 expression and esophageal and tongue carcinogenesis

Oral Cancer - Finding abnormal p16 methylation pattern may aid in early oral cancer detection

Oral Health - Midland, Texas, child youngest ever to have wisdom teeth pulled

Orthopedics - Bone specialists develop high-tech answer to patient care

Orthopedics - Tool to examine bone quality for space, earth-based diagnosis

Osteoporosis - Bone response to PTH and high-dose E2 involves patterned gene regulation

Osteoporosis - Effects of alendronate last longer after discontinuation than estrogen

Osteoporosis - Findings advance knowledge in osteoporosis research

Osteoporosis - Hip fracture estimated to comprise 0.1% of global burden of disease in 1990

Osteoporosis - Research add new data to osteoporosis body of knowledge

Osteoporosis - Researchers' findings advance osteoporosis research

Osteoporosis - Studies add new findings to osteoporosis body of knowledge

Osteoporosis - Studies describe new findings in osteoporosis research

Osteoporosis - Wyeth selects drug targets in osteoporosis collaboration with Belgium company

Otorhinolaryngology - Across- and within-channel envelope interactions characterized

Otorhinolaryngology - Clinical features of temporal arteritis reviewed

Otorhinolaryngology - Cochlear implant magnet migration reported

Otorhinolaryngology - Functional effects of esophageal caustic strictures determined in children

Ovarian Cancer - Assay combination has potential to double response rate to chemotherapy

Ovarian Cancer - Cell lines analyzed using array-based comparative genomic hybridization

Ovarian Cancer - Company enrolls, initiates reviews phases of clinical trials for cancer drug

Ovarian Cancer - Progesterone signaling appears to influence disease risk

Pain Medicine - Novel encapsulation method improves efficacy of intrathecal chromaffin cells

Pain Medicine - Outcomes of anesthetic-delivery device following mastectomy reported

Pancreatic Surgery - Management of inflammatory arrosion hemorrhage described

Parkinson Disease - Parkinson disease affects well being of patients' adolescent and adult children

Patents - Anesthetic delivery system developer announces new patent protection

Patents - Biotech company acquires gene encoding patent from Akademikliniken AB of Sweden

Patents - Company gets patent for differentiating hESCs into neural cells

Patents - Company secures license to SirT2 and SirT3 patents from University of California

Patents - Diagnostics products developer announces patent issuance

Patents - European patent granted for learning and memory compound

Patents - Medical device maker acquires intellectual property portfolio

Patents - Patent approved in Canada for bone graft material

Patents - Patent granted for detecting environmentally toxic dioxin-like chemicals

Patents - Patent infringement lawsuit filed against Insmed for growth hormone treatment

Patents - Remote ICU monitoring technology company challenges Visicu's patent rights

Patents - Surgical technology company announces patent for bladeless tip technology

Patents - Telemedicine patent granted in Australia

Patents - U.S. patent allowed for stabilized hydroxyvitamin D2 products

Patient Care - Nonprofit group takes photos of ailing kids

Patient Compliance - Compliance is compromised when patients are treated with multiple pills

Patient Safety - AIG Healthcare joins forces with patient group

Patient Safety - Forum for chief nursing officers emphasizes role of nurses in patient safety

Patient Safety - Quality measurement tools used for adult hospitals can apply to children's

Pediatric Cardiology - Nine-month-old girl receives nonsurgical heart valve replacement

Pediatric Oncology - Auto company retailers help raise $1 million for pediatric cancer research

Pediatrics - Incidence of surgeries in children with childhood orthopedic diagnoses studied

Pediatrics - Narrow measures govern neurogenetic models of ADHD etiology

Pediatrics - New clinical guidelines advise when to treat flat feet in children

Pediatrics - Obesity rising among U.S. preschoolers

Pediatrics - Vision system effective in detecting preverbal children's vision deficits

Peptide Signaling - Chemotaxis triggering studied, synergistic effect of two regulators revealed

Perception - How does the brain tune out odors?

Perception - Scents and emotions linked by learning

Peripheral Blood - Recombinant IL-2 analog induces proliferation of unstimulated T cells

Personnel - Agriculture processing company announces retirement of president

Personnel - Allergy-focused company appoints Deborah A. Smeltzer as CFO

Personnel - Arkansas leader appointed to U.S. House committee covering energy health issues

Personnel - Biopharma company announces vice president, general counsel and secretary

Personnel - Biopharma company names CEO

Personnel - Biopharma company names new board member

Personnel - Biopharmaceutical company names director of pharmaceutical development

Personnel - Biotech company announces promotions, appointments

Personnel - Biotech company names Thomas E. Shenk to board of directors

Personnel - Biotechnology company appoints director of regulatory affairs

Personnel - Biotechnology company names vice president, worldwide sales

Personnel - Brain monitoring technology firm names David W. Feigal Jr. to board

Personnel - Byproducts company announces board addition, president and CEO

Personnel - California controller names Philip Pizzo, MD, to stem-cell oversight committee

Personnel - Cardiologist elected Society for Women's Health Research board chair

Personnel - Charles B. O'Keeffe named to board of Florida-based pharmaceutical company

Personnel - Charles Craig named president of BIO's Georgia affiliate

Personnel - Children's Hospital of Pittsburgh names new president and CEO

Personnel - Dental services company announces reorganization

Personnel - Digital surgical device company names Robin Blackstone, MD, to board

Personnel - Dow AgroSciences executive joins Indiana life sciences initiative

Personnel - Dr. Goran Ando joins board of directors

Personnel - Drug development company names science and technology advisors

Personnel - Eclipsys names John A. Adams as executive VP and chief administrative officer

Personnel - Former Massachusetts governor Jane Swift appointed to health insurer's board

Personnel - Glen Tullman, CEO, named to leadership council of clinical software provider

Personnel - Health minister, battling cancer, says he likely will resign

Personnel - Health performance measurement company announces addition to board

Personnel - Healthcare marketing research consultancy announces appointments in Europe

Personnel - Hythiam names vice president of scientific affairs

Personnel - Lab chip maker names Thomas T. Higgins chief financial officer

Personnel - Leslie J. Williams named president, CEO of pharmaceuticals company

Personnel - Maclyn McCarty, MD, genetic research pioneer, dies at 93

Personnel - Medical device company announces board member addition

Personnel - Medical device company announces new board members

Personnel - Medical device company appoints member to board

Personnel - Medical device firm announces management expansion

Personnel - Medical technology company appoints vice president of business development

Personnel - New York City hospitals chief leaving post for private-sector job

Personnel - Pain-management company announces executive appointments

Personnel - Pharmaceutical firm appoints Robert Roe to board of directors

Personnel - Plant technology company appoints director of finance and administration

Personnel - Prescription savings company names Mark Chamness VP of pharmacy networks

Personnel - President names former Virginia Secretary of Health domestic policy adviser

Personnel - Richard C. Williams named interim CEO of specialty biopharmaceutical company

Personnel - Therapeutics company names member to board

Personnel - Vijay Sondhi appointed chief financial officer by pharmaceutical company

Personnel - West Virginia leader signals departure from Health agency

Personnel - William Nuerge named CEO of women's health and urology focused drug company

Personnel - William Siart resigns from board of dental-products company

Personnel - Wyoming leader plans to step down as health director

Personnel - Wyoming leader to chair Senate health committee

Pheromones - Enhancement of pheromone response in yeast reported

Philanthropy - Antibiotics valued at $50M donated to AmeriCares

Philanthropy - Florida philanthropist Alexander W. Dreyfoos gives Scripps Institute $1 million

Philanthropy - GPI to help bring medical aid to South Asia

Philanthropy - ING Vysya Foundation, Sev Mandir to support water harvesting project in India

Philanthropy - Pharmaceutical company contributes $300K, products to tsunami relief efforts

Philanthropy - Records show $1 billion donated to faith-based groups

Phosphatase - Expression, characterization, and analysis of purple acid phosphatase reported

Physiology - Caveolin-1 analyzed, functional form necessary for alpha-hemolysin assembly

Physiology - Increased uterine flow impedance found in older pregnant women

Physiology - Organ of corti potentials and the motion of the basilar membrane revealed

Physiology - Potassium channel subunit and aquaporin-4 are localized to cerebellar pinceau

Physiology - Study evaluated effects of nutritional stress on AMPK activity in vivo

Physiology - Study examined fatty acyl CoA synthetase from Antarctic fishes

Plague - Virulence factor expression in Yersinia pestis characterized

Plant-based Medicine - Tea tree oil's antimicrobial activity studied in Staph. aureus-infected wounds

Platelets - rFVIIa results in activation of FIX to form additional tenase complexes

Pneumococcal Vaccines - Recent findings in pneumococcal vaccines described

Pneumonia - Procalcitonin a prognostic marker for outcome in pneumonia

Pompe Disease - Company files for European approval of Myozyme for Pompe disease

Porphyromonas Gingivalis - Oxidative damage repair studied in Porphyromonas gingivalis

Positron Emission Tomography - Application demonstrated new radiotracer to be safe and useful

Pre-eclampsia - Researchers find protein predicts pregnancy complication

Preeclampsia - Protein in urine may warn of preeclampsia risk

Premature Birth - Outlook is bleak for the smallest premature babies: 80% have impairment

Preventive Medicine - 20M smokers resolve to quit in 2005 again

Preventive Medicine - Medical Reserves Corps offers Heart Healthy Firefighter program

Product Licensing - Biopharmaceutical company licenses human protein BPI to Zephyr Sciences, Inc.

Product Licensing - CAD, 3-D imaging companies announce licensing agreement for computed tomography

Product Licensing - CTI licenses Lisofylline and related portfolio for development in diabetes

Product Licensing - Company inks licensing agreement in Mexico for Decapeptyl Depot, Decapeptyl LA

Product Licensing - HEALTHPOINT enters licensing agreement for two late-stage topical analgesics

Product Licensing - License agreement for glioblastoma multiforme treatment candidate signed

Product Licensing - License rights for gene targeting technologies granted to Johnson & Johnson

Product Licensing - Pharmaceutical companies finalize license agreement for common cold therapeutic

Professional Education - Former house speaker to present at health care congress

Prostate Cancer - Calcitriol induces prostate-derived factor expression in tumor cells

Prostate Cancer - Company reaches milestone in development of prostate cancer classification test

Prostate Cancer - Experience with Vattikuti Institute prostatectomy reported

Prostate Cancer - Modified yeast assay improves detection of p53 abnormalities in prostate cancer

Prostate Cancer - More precise radiation therapy lets patients avoid erectile dysfunction

Prostate Cancer - Researchers report on case of spinal cord metastasis from prostate cancer

Prostate Cancer - Retinol, lycopene not significantly related to prostate cancer risk in study

Protein Folding - Wild-type spectrin domains of the same stability vary kinetically

Protein Methylation - Stable HeLa cell protein methylation produced by adenosine dialdehyde treatment

Protein Structure - Predictive models for protein crystallization developed

Proteins - Heart, tooth germ, and kidney are sites of P-B expression

Proteolysis -  Xenopus laevis egg envelope hardening studied, role of proteolysis revealed

Proteomics -  Escherichia coli MntH studied, importance of acidic residues revealed

Proteomics - Activation and activity of protein kinase isoforms of a bivalve mollusk studied

Proteomics - Application of mass spectrometry data to proteomics research described

Proteomics - Bone morphogenetic proteins are secreted early during embryonic development

Proteomics - Desensitization of activated sphingosine-1-phosphate receptors revealed

Proteomics - Lipid activation of beta 2-chimaerin analyzed, structural mechanism revealed

Proteomics - Mediation of protein sorting to the mitochondrial intermembrane space revealed

Proteomics - Melanocortin receptor subtypes studied, preference to specific peptides revealed

Proteomics - Nonspecific interaction between cytochromes b(5) and P450 revealed

Proteomics - Novel peptide array enables efficient kinome analysis

Proteomics - Peptic cleavage of bovine beta-casein studied, peptides characterized

Proteomics - Phospholipase C-epsilon studied, activation mechanism revealed

Proteomics - Photoperiod-regulated expression of gene encoding a CO/COL homolog studied

Proteomics - Properties of mutant alpha-tropomyosin were compared to wild protein

Proteomics - Protection techniques foster the construction of oligonucleotide constructs

Proteomics - Proteins with fullerol studied, detection by light scattering determined

Proteomics - Rapid analysis of large protein-protein complexes using NMR developed

Proteomics - Real-time organelle analysis performed using surface plasmon resonance

Proteomics - Reports advance knowledge in proteomics research

Proteomics - Researchers report details of new studies and findings in the area of proteomics

Proteomics - STA1 expression in yeast studied, role of Swi/Snf complex clarified

Proteomics - Scaffolding protein regulates NMDA channel gating and surface expression

Proteomics - Shape changes in Arf1 linked to nucleotide exchange and loss of binding sites

Proteomics - Structural basis of cellular redox regulation by human TRP14 described

Proteomics - Study investigated determinants of PIP2 interaction with HERG

Proteomics - Zinc-finger protein TIS11b destabilizes angiogenic cytokine

Pseudomonas - MucA-mediated coordination of secretion in Pseudomonas investigated

Psoriatic Arthritis - U.S., European submissions made for Humira

Public Health - Gangrene, pneumonia, and risk of malaria in some tsunami refugee camps

Pulmonary Hypertension - Results from STRIDE-4 released

Pulmonary Hypertension - U.S. FDA approves Ventavis for pulmonary arterial hypertension

Pulmonary Hypertension - Vasoactive mediators from smoke exposure provoke pulmonary artery changes

Quality Assurance - Consultants present long list of fixes for Los Angeles hospital

Quality Assurance - Methods may help in designing methods of quality control for interviews

Quality Assurance - Oregon nursing homes improve as a result of quality initiative

Quality Assurance - Vermont hospitals file new reports with state detailing services provided

RNA Research - DNA and RNA surveillance are linked to mRNA export

RNA Research - Fourier transform infrared spectroscopy discerns RNA bulge structures

RNA Research - Mullerian duct analyzed, altered matrix metalloprotein mRNA expression revealed

RNA Research - RNA polymerase II-dependent promoter derivatives expand the potential of siRNA

Rabies - First rabies survivor without vaccination leaves hospital

Radiotherapy - Risk estimation made of hereditary effects due to radiation therapy

Receptor Studies - Entrapment of membrane-bound receptors in silica reported

Receptor Studies - Opioid receptor blockade helps mice escape Fas-induced hepatitis

Receptor Studies - Quantitative analysis of drug-protein binding conducted

Receptor Studies - Toll-like receptors may be targets for treating chronic inflammatory diseases

Receptors - VPAC(1) receptors studied, inverse antagonism revealed

Recombinant Research - Heat shock proteins used to produce recombinant proteins in E. coli

Reconstructive Microsurgery - Peripheral nerve regeneration within nerve conduit characterized

Regulatory Issues - Discount health plans crackdown by state stops false and misleading advertising

Regulatory Issues - Treating individuals: How generalizable are trial data?

Renal Cancer - Angiogenesis inhibitors help patients with advanced renal cell carcinoma

Renal Cell Carcinoma - Use of retinoids in the treatment of renal cell carcinoma may be a futile effort

Renal Disease - Chloride channel Kb gene mutations direct renal tube cell calcium handling

Renal Disease - Company partners with ADDNET consortium

Renal Disease - Kidney disease in Arima syndrome resembles disease in other disorders

Renal Disease - Renal complications in Fabry disease associate with a unique gene variant

Reproductive Biology - Blocked and non-blocked 2-cell stage embryos are susceptible to culture effects

Reproductive Biology - Changes in NO production cause uterine quiescence in pregnancy, start of labor

Reproductive Biology - Genetic selection of mouse male germline stem cells demonstrated

Reproductive Biology - Mechanism of VEGF-induced uterine venous hyperpermeability elucidated

Respiratory Medicine - Bronchoalveolar lavage fluid tests do not reflect pulmonary fibrinolysis

Respiratory Medicine - Interferon benefits patients with recurrent respiratory papillomatosis

Respiratory Medicine - Phase II trial initiated to study aerosolized antibiotic for pneumonia

Respiratory Medicine - Vitamin D receptor gene polymorphisms links to asthma and allergy studied

Retinopathy - Upregulated VEGF in RPE cells does not produce choroidal neovascularization

Rheumatic Heart Disease - Mannose-binding lectin may cause complement activation that leads to RHD

Rheumatoid Arthritis - Long-term outcome of posterior-cruciate-retaining TKA clarified

Rhodopsin - Rhodopsin crystallized; native, altered and heavy atom forms studied

Rhodopsin - Rhodopsin signaling and organization studied in knockout mice

Ribosomes - Small ribosomal subunit changes shape during translocation

Rounded Atelectasis - Researchers report on asbestos-exposed worker with rounded atelectasis

SARS - An unusual RNA structure in the SARS virus offers a promising target

SARS - Assay for studying mutations of SARS virus protease developed

SARS - Geographic information system offered real-time tracking of SARS spread

SARS - Polyprotein cleavage and chemical modification of SARS proteinase reported

SARS Coronavirus - Reports describe recent advances in SARS coronavirus research

SARS Prevention - Knowledge level regarding SARS transmission associated with formal education

Salla Disease - Mutations in transporter protein shed light on neurodegenerative diseases

Salmonella - B12 -adenosyl transferase encoded within Salmonella enterica operon

Salmonella - Lack of YggX results in chronic oxidative stress in Salmonella

Salpingitis - New bacterial phylotypes found in Fallopian-tube specimens

Sarcoidosis - North Carolina researchers look for link to disease behind White's death

Scabies Diagnostics - Asymptomatic S. scabiei infestation revealed by serology of Caprinae hosts

Sexual & Reproductive Health - New drug application submitted for premature ejaculation

Sexual and Reproductive Health - Diet does not influence reproductive outcomes in mice lacking the Socs-2 gene

Sexual and Reproductive Health - Murine scans identify genes associated with oocyte maturation

Sexual and Reproductive Health - Primary follicles are stockpiled in polycystic ovary syndrome

Skin Cancer - Melanocortin 1 receptor variants affect skin cancer susceptibility

Small Bowel Transplantation - Nitric oxide production in epithelial cells is synergistically stimulated

Smallpox Vaccines - Recent findings in smallpox vaccines provide new insights

Smooth Muscle Cells - Epidermal growth factor receptor involved in vascular smooth muscle growth

Social Stress - During social stress, catecholamines play role in blood-leukocyte redistribution

Sociological Research - Report describes issues regarding the typology of maritally violent men

Soft Tissue Sarcoma - Licensed oncology drug for soft tissue sarcoma in clinical trials at Wayne State

Spinal Cord Compression - Researchers report on vertebroplasty for tumor-related spinal cord compression

Spinal Cord Injury - BMTs provide tissue protection/axon guidance after contusive spinal cord injury

Spinal Cord Injury - Federal grant to be used for cell therapy research

Staffing - Healthcare officials say man worked as nurse without license

Staffing - Maker of contrast agent renews contract with Canadian Union

Staffing - Nursing shortage may be hurt by new State Department practice

State Medicaid - Florida Medicaid renews contract with HMS for revenue recovery services

State Medicaid - Iowa Governor says raise cigarette tax to help fund Medicaid

State Medicaid - Mississippi's top lawmaker worries Medicaid shortfall could grow

State Medicaid - New state Medicaid reform proposals released in New Hampshire

Statins - Consumers, pharmacists are more positive than doctors about OTC statins

Stem Cell Research - CD19+/CD20+ cells efficiently separated via magnetic cell separation technique

Stem Cell Research - CXCR4 important for mediating specific migration of MSCs to bone marrow

Stem Cell Research - Criticism of new $3 billion California stem cell agency mounts

Stem Cell Research - Delayed TNF-alpha exposure increases yield of CD83+ dendritic cells

Stem Cell Research - FGF6 role in maintenance of reserve pool of progenitor cells in skeletal muscle

Stem Cell Research - Hematopoietic stem cell expansion is a plausible clinical goal

Stem Cell Research - MMG disrupts collagen I/integrin signaling during osteoblastic differentiation

Stem Cell Research - Mesangioblasts transdifferentiate into satellite cells in myogenic environment

Stem Cell Research - Mesenchymal progenitor cells are present in the umbilical cord

Stem Cell Research - Microfabricated platform studies stem cell fates

Stem Cell Research - Non-muscle stem cells do not regenerate normal muscle tissue

Stem Cell Research - Nucleostemin plays important role in self-renewal of cancer cells

Stem Cell Research - Oct4 required for primordial germ cell survival

Stem Cell Research - Physical defect repair enhanced by implanting MSC cultured with TGF-beta 3

Stem Cell Research - SKPs can be isolated from skin during embryogenesis and persist into adulthood

Stem Cell Research - StemCells Inc. seeks trial of stem cells in Batten disease

Stem Cell Research - Trabecular bone fragment alternative source of mesenchymal stem cells

Stem Cell Research - hEBs generated from ESC suspensions within 3D porous alginate scaffolds

Stem Cell Transplantation - GVHD still a major limitation to successful hematopoietic SCT

Stem Cell Transplantation - HD radiochemotherapy followed by ASCT improves survival in follicular lymphoma

Stem Cell Transplantation - Non-myeloablative SCT safer than myeloablation for autoimmune diseases

Stenosis - NT pro-BNP is a useful marker for evaluating aortic stenosis

Stents - Researchers prefer stenting for SA obstructive lesions

Stents - Study evaluated effects of beta-irradiation for in-stent restenosis

Stress - Mothers in the workplace held to stricter standards, study suggests

Stress - Study suggests women suffer more stress than men and handle it differently

Stress Induction - Multiple stress signals induce p73 beta accumulation

Stroke - HealthEast hospitals earn Joint Commission Primary Stroke Center Certification

Stroke - Heavy drinking linked to higher stroke risk

Stroke - Ischemic stroke review provides data on hypertension and hyperlipidemia

Stroke - Risk is greater for migraine sufferers, especially those on oral contraceptives

Stroke - Specific gene variations may pose a risk for ischemic stroke

Substance Abuse - Australian group calls for revised guidelines on alcohol during pregnancy

Substance Abuse - CDC grant enables research on alcohol-exposed pregnancies to continue

Sudden Infant Death Syndrome - Repeated unexpected infant deaths most likely to be from natural causes

Surgical Devices - Guidewire can be useful tool in treatment of chronic total occlusions

Surgical Devices - Study assessed patient tolerance and utility of using closure device

Surgical Technology - Adipose-derived stem cells for repairing human skull defects reported

Surgical Technology - Axial femorotibial rotation after TKA characterized

Surgical Technology - Carter-Thomason CloseSure System XL launches in the United States

Surgical Technology - Collegium announces licensing agreement for two late-stage products

Surgical Technology - Company reports first major peer-reviewed clinical article on PARSUS technology

Surgical Technology - Conference to highlight developments in cosmetic surgery

Surgical Technology - Evolution of robotic urologic surgery reviewed

Surgical Technology - FDA issues 510(k) clearance for CardioPAT surgical blood salvage system

Surgical Technology - High-flexion knee arthroplasty design replicates healthy motion

Surgical Technology - Image-based computer-assisted TKA has lower coronal alignment variability

Surgical Technology - Imaging center announces noninvasive procedure for uterine fibroids

Surgical Technology - Long-term efficacy of unicompartmental knee replacement determined

Surgical Technology - Morselized bone grafts stabilize cementless acetabular revisions

Surgical Technology - Outcome of different TKA configurations evaluated

Surgical Technology - Percutaneous treatment of renal artery stenosis effective in children

Surgical Technology - Polyethylene bearing mobility preserved in posterior stabilized TKA

Surgical Technology - Report looks at European market for bone morphogenic proteins in spine fusion

Surgical Technology - Report published examining forecast in eight major surgical specialties

Surgical Technology - TVAC is a promising device to protect microcirculation in reperfusion

Systemic Lupus Erythematosus - U.S. FDA grants epratuzumab Fast Track Product designation

Tangier Disease - Cassette transporter A1 requires a specific motif for several activities

Thrombin - Lung barrier function studied, differential thrombin regulation revealed

Thyroid Hormone - Na, K-ATPase activity and expression studied, role of two kinases revealed

Tobacco Use - American Lung Association gives Oregon poor grades

Tobacco Use - Nicotine increases blood-brain barrier permeability in vivo

Toxicology - Cell sorting techniques are not genotoxic to spermatozoa

Toxicology - Method for in vivo bioluminescent monitoring of toxicity developed

Toxicology - Synthesized compounds immobilize cadmium or lead toxins

Toxicology - Tool to study oxidative stress and inhalation toxicokinetics developed

Transcription Factors - R-dependent transcription factor activity studied, different mechanisms revealed

Transfection - Researchers detail new studies and findings in the area of transfection

Transitional Cell Carcinoma - Researchers report on transitional cell carcinoma in renal transplant recipients

Transplant Medicine - Donor-derived, alloreactive natural killer cells may interfere with immunity

Transplant Medicine - Researchers provide details of new studies and findings in the area of transplant medicine

Trichomonas vaginalis -  T. vaginalis inhibits proinflammatory cytokines via NF-kappa B supression

Trypanosoma - Plant arginine decarboxylase gene expressed in Trypanosoma cruzi

Tuberculosis - Companies sign agreement to assess potential of tuberculosis testing technology

Tuberculosis - Concepts of gender, culture, and TB explored among uninfected Indian population

Tuberculosis - Woman died of tuberculosis in November, health officials say

Tuberculosis Diagnosis - Simple sputum test useful to confirm childhood tuberculosis

Tumor Suppression - Cdk inhibitor p21 has tumor suppressor function in colon

Type 1 Diabetes - Intracellular stress signaling pathways activated during islet preparation

Type 1 Diabetes - Sources for new pancreatic beta cells in adult life outlined

Type 1 Diabetes Screening - Simple test for autoantibodies to glutamic acid decarboxylase developed

Type 2 Diabetes - 7-Hydroxystaurosporine inhibits Akt Thr308) not Ser473 phosphorylation

Type 2 Diabetes - Hepatic production of VLDL1 but not VLDL2 related to insulin resistance

Type 2 Diabetes - Stage-matched intervention promotes exercise in patients with type 2 diabetes

Ulcerative Colitis - Management of postoperative pouchitis reviewed

Urinary Tract Infections - Drug-resistant UTI outbreak likely caused by contaminated food

Urogenital Research - Feline urogenital junction studied, morphology and innervation pattern reported

Urology - Pelvic floor reconstruction reviewed

Uterine Fibroids - Interim assessment of 1-month data from uterine fibroid therapy released

Vaccine Development - Dendritic cell expansion potentiates the immunogenicity of plasmid DNA vaccine

Vaginal Infection - Mannose binding lectin and C3 act as recognition molecules for pathogens

Viral Genomics - Findings advance knowledge in viral genomics research

Virology - Aromatic cations eradicate viral infection in cells destined for cloning

Virology - DNA aptamer prevents influenza infection

Virology - New research in the area of virology detailed

Virology - Post-transcriptional RNA processing characterized in HSV-infected cells

Virology - Researchers' data advance virology research

Wilson Disease - Copper metabolism in Wilson disease clarified using proteomic analysis

Wound Care - Ethylene oxide is best method to sterilize chitosan wound dressings

Wound Care - Hydrogels as wound-dressing materials investigated

Zoonoses - Novel immunoassay suitable for diagnosis of porcine Nipah virus infection

von Willebrand Disease - Novel von Willebrand factor mutation causes skipping of nonadjacent exons

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