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Gastroenterology

Interferon-alpha and antisense K-ras RNA suppress pancreatic cancer cell growth

Published in Health and Medicine Week, January 24th, 2005

Interferon-alpha and antisense K-ras RNA suppress pancreatic cancer cell growth.

According to a study from Japan, "interferon alpha (IFN-alpha) is used worldwide for the treatment of a variety of cancers. For pancreatic cancer, recent clinical trials using IFN-alpha in combination with standard chemotherapeutic drugs showed some antitumor activity of the cytokine, but the effect was not significant enough to enlist pancreatic cancer as a clinically effective target of IFN-alpha."

"In general, an improved therapeutic effect and safety are expected for cytokine therapy when given in a gene therapy context, because the technology would allow increased...

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