Stem Cells Research
Alginate bead culture system differentiates MSC into articular chondrocytes
Published in Health and Medicine Week, January 31st, 2005
"Chondrogenesis involves the recruitment of mesenchymal cells to differentiate into chondroblasts, and also the cells must synthesize a cartilage-specific extracellular matrix. There were two representative culture systems that promoted the chondrogenic differentiation of human mesenchymal stem cells.
"These systems were adaptations of the 'pellet' culture system, which was originally described as a method for preventing the phenotypic modulation of chondrocytes, and the 'alginate bead' culture system, which was used to maintain encapsulated cells at...
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