Diabetes Pathogenesis
Increased albumin excretion in diabetes not related to charge selectivity
Published in Health and Medicine Week, January 31st, 2005
According to a study from Sweden, "The urinary albumin excretion rate is increased at the time of diagnosis of diabetes. We investigated whether this is caused by change in pore size or charge selectivity in the glomerular basement membrane. Urine excretion of immunoglobulins (IgG2, IgG4), glycosaminoglycans (GAG), and albumin was analyzed during the first 20 days after diagnosis of diabetes in children aged 4-15 years; 36 diabetic and 24 age-matched apparently healthy children were included."
"The excretion of albumin was significantly...
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