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Anti-infectives
Biodegradable antibiotic-releasing catheter polymer developed
June 13th, 2005
A biodegradable, antibiotic-releasing polymer has been developed as a catheter material. Scientists in South Korea devised "a biodegradable polymer that releases an antibiotic (nalidixic acid) slowly and continuously, for prevention of catheter-induced infection during drainage of cerebrospinal fluid." In their study, S.Y. Han and coauthors at Ajou University "investigated the in vitro antibiotic releasing characteristics and bacterial killing effects of the new polymer against E. coli." "The novel fluoroquinolone polymer was prepared using diisopropylcarbodiimide, poly (e-caprolactone) diol, and nalidixic acid," the...
Source: Health & Medicine Week (2005-06-13)
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