Gene Therapy
Strategies to enhance tumor visibility improve cancer immunotherapy
Published in Health and Medicine Week, June 20th, 2005
"Strategies that generate tumor antigen (Ag)-specific effector cells do not necessarily cure established tumors. We hypothesized that the relative efficiency with which tumor-specific effector cells reach the tumor is critical for therapy," researchers in the United States report.
"We demonstrate in this study that activated T cells respond to the chemokine CCL3, both in vitro and in vivo, and we further demonstrate that expression of CCL3 within tumors increases the effector T cell infiltrate in those tumors," wrote M. Gough and colleagues, Providence Portland Medical...
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